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Mucosal thickness

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https://www.readbyqxmd.com/read/29769429/mechanisms-involved-in-the-development-of-the-small-intestine-mucosal-layer-in-postnatal-piglets
#1
T H Skrzypek, W Kazimierczak, H Skrzypek, J L Valverde Piedra, M M Godlewski, R Zabielski
The use of complementary visualization and measurement techniques allowed accurate description and quantification of changes in the intestinal mucosal architecture and provided a comprehensive outlook on the dynamics of remodelling and maturation processes of the mucosal layer taking place in the small intestine of piglets from birth to weaning. The aim of the study was to examine the early postnatal development of the small intestine in pigs. Three techniques were used: scanning electron microscopy (measurements of villus density and shape, height of enterocytes and microvilli, cell exfoliation, and location of extrusion zones), optical microscopy (cross section, measurement of structures: villus length and width; crypt depth; mucosal thickness), and confocal microscopy (cell localization, apoptosis, exfoliation and migration)...
February 2018: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/29765955/pediatric-multiple-endocrine-neoplasia-type-2b-clinicopathological-correlation-of-perilimbal-mucosal-neuromas-and-treatment-of-secondary-open-angle-glaucoma
#2
Ta Chen Chang, Kingsley C Okafor, Kara M Cavuoto, Sander R Dubovy, Carol L Karp
Ocular findings of multiple endocrine neoplasia type 2B (MEN 2B) include prominent corneal nerves, mucosal neuromas of the conjunctiva, glaucoma, and dry eyes. A 15-year-old girl with MEN 2B presents with advanced secondary open-angle glaucoma and bilateral perilimbal masses. High-resolution optical coherence tomography (HR-OCT) of the perilimbal lesions showed normal epithelial thickness and subepithelial lobular areas of mixed reflectivity, which correlates well with histopathologic findings of benign mucosal neuromas...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29760785/monitoring-crohn-s-disease-activity-endoscopy-fecal-markers-and-computed-tomography-enterography
#3
Susana Lopes, Patrícia Andrade, Joana Afonso, Rui Cunha, Eduardo Rodrigues Pinto, Isabel Ramos, Guilherme Macedo, Fernando Magro
Background: The treatment goal of Crohn's disease (CD) has moved towards achieving mucosal healing, resolution of transmural inflammation, and normalization of biomarkers. The purpose of this study was to evaluate how well computed tomography enterography (CTE) and fecal calprotectin (FC) correlated with endoscopic activity in newly diagnosed patients with CD and after 1 year of therapy. Methods: Consecutive patients with newly diagnosed CD were evaluated by endoscopy, CTE, and FC at diagnosis and 12 months after beginning immunosuppression...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29757464/ultrasonography-for-non-invasive-and-real-time-evaluation-of-peri-implant-tissue-dimensions
#4
Hsun-Liang Chan, Khaled Sinjab, Junying Li, Zhaozhao Chen, Hom-Lay Wang, Oliver D Kripfgans
AIM: Existing methods for evaluating marginal bone loss and tissue biotype around dental implants present with many limitations. The aim of this study was to examine the accuracy of high-resolution, 3-dimensional ultrasound to measure peri-implant tissue dimensions. MATERIAL AND METHODS: A 25-MHz ultrasound probe prototype was used to scan peri-implant tissues of 17 implants from 7 fresh human cadavers. Four ultrasonic measurements were made: the marginal bone level/thickness, and mucosal level/thickness...
May 14, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29756244/helical-intensity-modulated-radiotherapy-with-concurrent-chemotherapy-for-oropharyngeal-squamous-cell-carcinoma-a-prospective-investigation-of-acute-swallowing-and-toxicity-patterns
#5
Laura B Moroney, Jennifer Helios, Elizabeth C Ward, Jane Crombie, Anita Pelecanos, Clare L Burns, Ann-Louise Spurgin, Claire Blake, Lizbeth Kenny, Benjamin Chua, Brett G M Hughes
BACKGROUND: Conformal radiotherapy modalities may minimize treatment toxicities. The purpose of this study was to document the extent and timing of dysphagia and related toxicities during helical intensity-modulated radiotherapy (IMRT) with chemotherapy for oropharyngeal squamous cell carcinoma (SCC). METHODS: We conducted a prospective study of 76 patients with oropharyngeal SCC undergoing helical IMRT with chemotherapy. Dysphagia and acute toxicity data were collected weekly during treatment and at 2, 4, and 12 weeks posttreatment using the Functional Oral Intake Scale, diet descriptors, and Common Terminology Criteria for Adverse Events (CTCAE) version 4...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29753524/short-bowel-mucosal-morphology-proliferation-and-inflammation-at-first-and-repeat-step-procedures
#6
Annika Mutanen, Meredith Barrett, Yongjia Feng, Jouko Lohi, Raja Rabah, Daniel H Teitelbaum, Mikko P Pakarinen
BACKGROUND: Although serial transverse enteroplasty (STEP) improves function of dilated short bowel, a significant proportion of patients require repeat surgery. To address underlying reasons for unsuccessful STEP, we compared small intestinal mucosal characteristics between initial and repeat STEP procedures in children with short bowel syndrome (SBS). METHODS: Fifteen SBS children, who underwent 13 first and 7 repeat STEP procedures with full thickness small bowel samples at median age 1...
April 17, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29750729/posterior-lamellar-reconstruction-of-the-lower-eyelid-with-a-gingivoalveolar-mucosal-graft
#7
Yahya Baltu
The anterior and posterior lamellae should be simultaneously reconstructed to repair the upper and lower eyelid's full thickness defects after resection of a malignant tumor. The author described a gingivoalveolar mucosal graft for posterior lamellar reconstruction of the lower eyelid. Between November 2014 and September 2017, 11 patients (6 women, 5 men; mean age 62.7 years) with 13 posterior lamellar defect of lower eyelid underwent reconstruction with gingivoalveolar mucosal graft. The defects ranged from 10 x 8 mm to 20 x 10 mm...
May 10, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29746316/the-clinical-significance-of-kit-mutations-in-melanoma-a-meta-analysis
#8
Hui Z Gong, He Y Zheng, Jun Li
This study aimed to evaluate the association of KIT mutations with clinicopathologic features of melanomas using a meta-analysis and to identify differences between Asian and White populations using subgroup analyses. We selected 32 studies from the literature including 5224 patients. The pooled data were combined, and odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Heterogeneity and publication bias were also determined. KIT mutations were reported in 497 (9.5%) of 5224 patients with melanomas, and were associated significantly with age, clinical melanoma subtype, anatomic location, and chronic sun-damage (CSD), but not with sex, histological type, Breslow thickness, ulceration, mitotic rate, or tumor stage...
May 9, 2018: Melanoma Research
https://www.readbyqxmd.com/read/29707180/accuracy-of-guided-surgery-via-stereolithographic-mucosa-supported-surgical-guide-in-implant-surgery-for-edentulous-patient-a-systematic-review
#9
REVIEW
Cheongbeom Seo, Gintaras Juodzbalys
Objectives: The purpose of the present study is to systematically review the accuracy of implant placement with mucosa-supported stereolithographic surgical guide and to find out what factors can influence the accuracy. Material and Methods: An electronic literature search was performed through the MEDLINE (PubMed) and EMBASE databases. The articles are including human studies published in English from October 2008 to October, 2017. From the examination of selected articles, deviations between virtual planning and actual implant placement were analysed regarding the global apical, global coronal, and angulation position...
January 2018: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29696734/pediatric-helicobacter-pylori-gastropathy-demonstrates-a-unique-pattern-of-gastric-foveolar-hyperplasia
#10
Sadaf Saghier, Steven M Schwarz, Virginia Anderson, Raavi Gupta, Amin Heidarian, Simon S Rabinowitz
OBJECTIVES: Helicobacter pylori (Hp) are the most common agents causing gastric mucosal injury worldwide. Foveolar hyperplasia is a key component of the stomach's reaction to injury. This study examines histopathologic characteristics associated with Helicobacter pylori and with non- Helicobacter pylori-associated gastropathy in children and adolescents, and compares the prevalence of foveolar hyperplasia among these disease subgroups and normal control subjects. METHODS: Eighty-one gastric antral and corpus biopsies from subjects 2-19 years of age were studied...
April 25, 2018: Helicobacter
https://www.readbyqxmd.com/read/29694333/effect-of-taste-masking-technology-on-fast-dissolving-oral-film-dissolution-rate-and-bioavailability
#11
Ying Zhu, Xinru You, Keqing Huang, Faisal Raza, Xin Lu, Yuejian Chen, Arvind Dhinakar, Yuan Zhang, Yang Kang, Jun Wu, Liang Ge
Fast dissolving oral film is a stamp-style drug loaded polymer film with rapid disintegration and dissolution. This new kind of drug delivery system has harsh requirements on the taste-masking technology. Suspension intermediate and liposome intermediate were prepared respectively for the formulation of two kinds of fast dissolving oral films with aim of studying the effect of taste masking technology on bioavailability of oral films and loratadine was selected as the model drug. The surface pH of films was close to neutral without oral mucosal irritation or side effects...
April 25, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29692527/gangrenous-cholecystitis-analysis-of-imaging-findings-in-histopathologically-confirmed-cases
#12
Binit Sureka, Archana Rastogi, Amar Mukund, Shalini Thapar, Ajeet Singh Bhadoria, Tushar Kanti Chattopadhyay
Purpose: To study the imaging findings in gangrenous acute cholecystitis. Materials and Methods: Retrospective analysis of imaging findings in 31 histopathologically confirmed cases of gangrenous cholecystitis was done. The following imaging findings were analyzed: wall thickness, gallbladder distension, intraluminal membranes, mural striation, edema, wall enhancement, gallstones, gas, pericholecystic fluid, stranding, hemorrhage, hyperaemia in adjacent liver, mucosal/wall irregularity, complications...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29692508/comparison-of-the-efficiency-and-complications-of-lumenis-and-wolf-morcellators-after-holmium-laser-enucleation-of-the-prostate
#13
Pankaj N Maheshwari, Vinayak G Wagaskar, Reeta P Maheshwari
Introduction: Holmium laser enucleation of the prostate (HoLEP) is a recognized option for the surgical management of benign prostatic hyperplasia. While the laser parameters and enucleation techniques have been widely studied, the morcellation techniques still remain under-evaluated. The current study evaluates the two commonly used morcellation devices for their in vivo efficiency and patient safety. Materials and Methods: A total of 222 patients who underwent HoLEP at two medical centres between January 2011 to December 2013 by a single surgeon were included...
April 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29686919/grinspan-s-syndrome-a-rare-case-with-malignant-transformation
#14
Numan Kökten, Lokman Uzun, Ayşe Serap Karadağ, Tülay Zenginkinet, M Tayyar Kalcıoğlu
Aim: Oral lichen planus (OLP) is one of the common chronic inflammatory, noninfectious, and precancerous oral mucosal diseases that affect the stratified squamous epithelium in adults. Grinspan et al. reported an association of OLP with diabetes mellitus and vascular hypertension and called that Grinspan's syndrome in 1966. We aim to present a case of Grinspan's syndrome with malignant transformation. Case Presentation: A 60-year-old man who presented with a ten-year history of OLP diagnosed clinically and histologically was referred to our otolaryngology department with a painless swallowing in the left buccal mucosa for 3 months...
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29682624/non-exposed-endoscopic-wall-inversion-surgery-for-gastrointestinal-stromal-tumor
#15
Takashi Mitsui, Hiroharu Yamashita, Susumu Aikou, Keiko Niimi, Mitsuhiro Fujishiro, Yasuyuki Seto
Laparoscopic and endoscopic cooperative surgery (LECS) is an accepted method of laparoscopic wedge resection, which is minimally invasive, for gastrointestinal stromal tumors (GISTs). We established a type of LECS achieving a full-thickness resection, non-exposed endoscopic wall-inversion surgery (NEWS), in an effort to prevent exposure of the peritoneal cavity to gastric intraluminal contents. We employed this surgical technique in 28 gastric GIST patients. We failed to complete NEWS in the initial two patients and in one patient with a large tumor (40 mm × 35 mm), but otherwise carried out the procedure successfully...
2018: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29673584/a-30-minutes-supraceliac-aortic-clamping-in-the-rat-causes-death-due-to-an-inflammatory-response-and-pulmonary-lesions
#16
Antoine Monnot, Anaïs Dumesnil, Sylvanie Renet, Marie Laurence Roquet, Vincent Richard, Didier Plissonnier
BACKGROUND: The treatment of thoraco-abdominal aortic aneurysms through an open approach has general and pulmonary consequences of multiple etiologies. Our assumption was that the supraceliac aortic clamping needed for this operation causes a systemic inflammatory response associated with a pulmonary attack. MATERIAL AND METHODS: We developed a model of 30 min supraceliac aortic clamping in Wistar rats weighing 300 g. After 90 min of reperfusion the rats were sacrificed...
April 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29666926/segmental-reversal-of-distal-small-intestine-in-short-bowel-syndrome-a-study-on-the-influence-on-postoperative-weight-and-intestinal-topography-in-piglets
#17
Pernille Kock Grave, Sabrina Valentin Thomsen, Pia Susanne Clark, Gunvor Iben Madsen, Niels Qvist, Mark Bremholm Ellebæk
PURPOSE: The objective of the present study was to investigate the effect of segmental reversal of the distal 20 cm of the small intestine in piglets with induced SBS compared to controls with SBS alone. Primary endpoint was postoperative weight change over a period of 1 month. Secondary endpoints were the influence on cell proliferation and mucosal architecture shown by histological analysis. METHODS: Sixteen piglets underwent a 60% resection of the distal small intestine and were randomized into two groups...
April 17, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29665060/combined-caudal-superficial-epigastric-axial-pattern-flap-and-full-thickness-buccal-mucosa-graft-for-single-stage-preputial-reconstruction-in-six-dogs
#18
F Massari, V Montinaro, P Buracco, G Romanelli
OBJECTIVE: To describe the use of a caudal superficial epigastric flap in combination with a full-thickness oral mucosal/submucosal graft for single-stage reconstruction of extensive preputial defects in dogs. MATERIALS AND METHODS: Medical records of dogs with extensive preputial defects either of traumatic origin or derived from tumour excision were reviewed. In all dogs, the prepuce was reconstructed using a full-thickness oral mucosal/submucosal graft combined with a caudal superficial epigastric axial pattern flap during a single surgical procedure...
April 17, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29650914/-surgical-procedure-of-buccal-mucosal-carcinoma-reconstruction-of-mouth-angle
#19
Aya Yoshino, Takahiro Kanno, Masaaki Karino, Teruaki Iwahashi, Joji Sekine
Surgical resection of the buccal mucosal carcinoma often induces soft tissue defect. The treatment plan should be considered to preserve oro-facial function and morpho-esthetics. This retrospective study reports the surgical reconstruction procedures in buccal mucosal carcinoma patients. We evaluated 4 cases(2 men, 2 women, mean age: 81.8 year-old)treated in Department of Oral and Maxillofacial Surgery, Shimane University Hospital between June 2007 and January 2017. The average size of primary tumor was 4.9 cm2...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29625238/infection-genetic-and-virulence-characteristics-of-porcine-epidemic-diarrhea-virus-in-northwest-china
#20
Xing-Ye Wang, Cheng-Jie Ji, Xue Zhang, De-Peng Xu, De-Li Zhang
From September 2015 to May 2016, epidemic outbreaks of a diarrheal disease caused severe economic losses to the swine industry in northwest China. Typical clinical symptoms of the disease included severe diarrhea, vomiting, dehydration and death. In order to identify the pathogen, 27 intestinal samples were collected from dead piglets in Shaanxi, Gansu and Qinghai provinces and from Ningxia Hui Autonomous Region. All samples were tested using RT-PCR to detect rotavirus (RV), porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV)...
April 3, 2018: Infection, Genetics and Evolution
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