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https://www.readbyqxmd.com/read/28626372/acute-appendicitis-caused-by-previous-endoscopic-submucosal-dissection-for-an-adenoma-adjacent-to-the-appendiceal-orifice
#1
Ryo Kato, Keita Harada, Kei Harada, Daisuke Takei, Yuusaku Sugihara, Shiho Takashima, Toshihiro Inokuchi, Masahiro Takahara, Sakiko Hiraoka, Yasushi Omura, Wakako Oda, Hiroyuki Okada
Endoscopic submucosal dissection (ESD) is a groundbreaking treatment for tumors adjacent to the appendiceal orifice that are difficult to remove by conventional endoscopic mucosal resection, and successful cases are increasingly reported. However, little is known about the subsequent complications, especially long-term complications. A female in her early 70s with a 15-mm cecal tumor adjacent to the appendiceal orifice - discovered incidentally during a screening colonoscopy - underwent hybrid ESD of the lesion...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28600969/prognostic-factors-and-treatment-outcomes-in-444-patients-with-mucosal-melanoma
#2
Markus V Heppt, Alexander Roesch, Benjamin Weide, Ralf Gutzmer, Friedegund Meier, Carmen Loquai, Katharina C Kähler, Anja Gesierich, Markus Meissner, Dagmar von Bubnoff, Daniela Göppner, Max Schlaak, Claudia Pföhler, Jochen Utikal, Lucie Heinzerling, Ioana Cosgarea, Jutta Engel, Renate Eckel, Alexander Martens, Laura Mirlach, Imke Satzger, Gabriele Schubert-Fritschle, Julia K Tietze, Carola Berking
BACKGROUND: Mucosal melanoma (MM) is a rare but diverse cancer entity. Prognostic factors are not well established for Caucasians with MM. PATIENTS AND METHODS: We analysed the disease course of 444 patients from 15 German skin cancer centres. Disease progression was determined with the cumulative incidence function. Survival times were estimated with the Kaplan-Meier method. Prognostic parameters were identified with multivariate Cox regression analysis. RESULTS: Common anatomic sites of primary tumours were head and neck (MMHN, 37...
June 7, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28598449/clinicopathological-study-of-malignant-melanoma-at-tertiary-care-centre
#3
S Thapa, A Ghosh, D Ghartimagar, T Prasad, R Narasimhan, O Talwar
INTRODUCTION: Malignant melanoma, which causes three fourth of all deaths related to skin cancer, is more common in Caucasian population compared to Asian population. There is no reliable information about malignant melanoma in Nepal hence an effort has been made to assess the clinical and pathological features of melanoma patients. METHODS: This was a retrospective hospital based study done in the department of Pathology. All cases of malignant melanoma diagnosed on biopsy during a period of 13 years were retrieved, reviewed and collated...
January 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28593788/a-complication-following-a-biopsy-sample-in-eosinophilic-esophagitis
#4
Antonio Cerezo Ruiz, Encarnación Parras Mejías, José María Martos Becerra
We present a case of a young 16 year old patient that had an esophageal perforation in the context of eosinophilic esophagitis. The esophagus showed vertical lacerations and mucosal thickness on endoscopy, thus a biopsy was performed in the proximal section which resulted in profuse bleeding due to a deep mucosal tear. A subsequent computed tomography scan revealed a perforation. Due to the absence of symptoms the patient was managed conservatively. The patient was discharged within 48 hours after admission...
June 8, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28576521/the-effect-of-caffeic-acid-phenethyl-ester-cape-on-tympanosclerosis
#5
İbrahim Ağrı, Arzu Erdal Ağrı, Mehmet Eser Sancaktar, Asude Ünal, Erkan Can, Mustafa Bakırtaş, Fatih Yılmaz, Mehmet Derya Demirağ, Recep Ünal
OBJECTIVE: To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis. MATERIALS AND METHODS: Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into their middle ears. Myringotomies were repeated for 5 weeks. Intraperitoneal (i...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28573173/ex-vivo-experimental-study-on-the-thulium-laser-system-new-horizons-for-interventional-endoscopy-with-videos
#6
Gian Eugenio Tontini, Helmut Neumann, Alessandro Rimondi, Sara Vavassori, Barbara Bruni, Gregorio Cattignoli, Ping-Hong Zhou, Luca Pastorelli, Maurizio Vecchi
BACKGROUND AND STUDY AIMS:  The Thulium laser system (TLS) is an emerging interventional tool adopted in many surgical specialties. Its 2.0-μm wavelength allows precise coagulation (0.2 - 0.4 mm in depth) and cutting, limiting the possibilities of collateral injuries. We tested the impact of the TLS for gastric endoscopic submucosal dissection (ESD) and per oral endoscopic myotomy (POEM) ex vivo in pigs. MATERIALS AND METHODS:   Ex vivo porcine stomach and esophagus models underwent 2 POEMs, and 3 ESDs (mean diameter 3...
June 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28545905/resveratrol-alleviates-oxidative-damage-in-enteric-neurons-and-associated-gastrointestinal-dysfunction-caused-by-chemotherapeutic-agent-oxaliplatin
#7
Elizabeth L Donald, Lily Stojanovska, Vasso Apostolopoulos, Kulmira Nurgali
Oxaliplatin is a first-line chemotherapeutic agent used for the treatment of colorectal cancer. Its use is associated with severe gastrointestinal (GI) side-effects, associated with oxidative damage and neurotoxicity to the enteric neurons. Resveratrol is a potent anti-oxidant that has been shown to protect against oxidative damage and neurotoxicity in other neurons and could therefore prevent oxaliplatin-induced damage to enteric neurons. We determined whether co-administration of resveratrol with oxaliplatin alleviates enteric neuron toxicity and GI dysfunction in mice...
May 17, 2017: Maturitas
https://www.readbyqxmd.com/read/28543798/mucosal-melanoma-clinical-histological-and-c-kit-gene-mutational-profile-of-86-french-cases
#8
E Cinotti, J Chevallier, B Labeille, F Cambazard, L Thomas, B Balme, M T Leccia, M D'Incan, P Vercherin, C Douchet, P Rubegni, J L Perrot
BACKGROUND: Mucosal melanomas are rare and highly aggressive tumors. Few studies evaluated mucosal melanomas of locations other than the head and neck region, and other than those of the Asian population. OBJECTIVES: The objective of this study was to analyze the clinical and histological features, as well as the mutational status of c-kit and b-raf gene of mucosal melanoma in any localization in a French series. METHODS: We investigated clinical (sex, age, performance status, survival, treatment of the patients and lack of pigmentation of the tumors) and histopathologic features (ulceration, Breslow's index, mitotic rate), as well as the mutational status of c-kit and b-raf of 86 mucosal melanomas diagnosed in 15 years in four French University Hospitals...
May 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28489125/severe-hypoproteinemia-as-a-harbinger-of-m%C3%A3-n%C3%A3-trier-s-disease-in-autoimmune-pancreatitis
#9
Julio Maria Fonseca Chebli, Liliana Andrade Chebli, Tarsila Campanha da Rocha Ribeiro, Pedro Duarte Gaburri
Ménétrier's disease is an extremely rare disease of unknown etiology causing gastric mucosal hypertrophy and protein-losing gastropathy. Rare cases of this condition have been reported in patients with autoimmune diseases. However, to the best of our knowledge, Ménétrier's disease associated with autoimmune pancreatitis (AIP) has never been reported. We described a case of severe hypoproteinemia as a harbinger of Ménétrier's disease associated with AIP. The patient was successfully treated with octreotide and high-protein diet, which led to symptomatic remission and significant improvement in serum levels of albumin and recovery of the nutritional status...
March 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28479684/redefining-epithelial-characterization-in-oral-submucous-fibrosis-using-morphometric-analysis
#10
Ajit Singh Rathore, Amit Gupta, Devi Charan Shetty, Kiran Kumar, Raghu Dhanapal
BACKGROUND: Oral submucous fibrosis (OSMF) is a chronic oral mucosal disease characterized by progressive deposition of collagen in subepithelial connective tissue and epithelial atrophy. The present study was conducted to evaluate the changes in epithelial thickness and cellular and nuclear morphometric characteristics of parabasal and spinous compartments of the epithelium in various stages of OSMF in comparison to normal epithelium. MATERIALS AND METHODS: Sample included 30 cases of OSMF of various stages and five cases of normal buccal mucosa...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28473890/evaluation-of-the-morphological-features-of-the-uterine-tubes-during-postnatal-development-in-west-african-dwarf-goats-capra-hircus
#11
Clifford Nwabugwu Abiaezute, Innocent Chima Nwaogu, Udensi Maduabuchi Igwebuike
The objective of this study was to highlight the postnatal development of the uterine tubes of the West African Dwarf goat from birth to 28 weeks of age by gross examination and light microscopy. There was a caudal migration of the paired uterine tubes from behind the paired kidneys at birth to the pelvic inlet at week 8 of age. Each uterine tube exhibited three segments namely; infundibulum, ampulla and isthmus. A marked flexure, the utero-tubal junction, was the point at which the uterine tubes joined the uterine horns...
2017: Veterinary Research Forum
https://www.readbyqxmd.com/read/28455798/internal-anal-sphincter-achalasia-data-from-a-nationwide-survey-of-allied-disorders-of-hirschsprung-s-disease-in-japan
#12
Satoshi Obata, Suguru Fukahori, Minoru Yagi, Makoto Suzuki, Shigeru Ueno, Kosuke Ushijima, Tomoaki Taguchi
PURPOSE: To investigate the incidence and treatment of internal anal sphincter achalasia (IASA) in Japan based on an analysis of data from a nationwide retrospective cohort study of the allied disorders of Hirschsprung's disease. METHODS: Five cases of definitive IASA were collected from a nationwide retrospective cohort study conducted from 2001 to 2010 and a search of the Japanese literature. RESULTS: Symptoms developed during the neonatal period in two patients, during early childhood in two, and at school age in one...
April 28, 2017: Surgery Today
https://www.readbyqxmd.com/read/28446013/the-in-vivo-effect-of-ytterbium-doped-fiber-laser-on-rat-buccal-mucosa-as-a-simulation-of-its-effect-on-the-urinary-tract-a-preclinical-histopathological-evaluation
#13
Songzhe Piao, Yue Wang, Young Ju Lee, Seungsoo Hong, Yoonchan Jeong, Seung-June Oh
PURPOSE: The aim of this study was to perform a histological analysis of the effect of a ytterbium-doped fiber (YDF) laser on oral buccal mucosa tissue in vivo to simulate its effect on the mucosa of the lower urinary tract. METHODS: A total of 90 8-week-old Sprague-Dawley rats were anesthetized with urethrane (1.2 g/kg intraperitoneally). A prespecified inner buccal mucosal site was irradiated with a YDF master-oscillator power amplifier (MOPA) system for 60 seconds, with output power settings of 0...
April 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28440238/thermal-ablation-of-pancreatic-cyst-with-a-prototype-endoscopic-ultrasound-capable-radiofrequency-needle-device-a-pilot-feasibility-study
#14
Maria Moris, Mustafa Atar, Abdurrahman Kadayifci, Murli Krishna, Ariston Librero, Eugene Richie, William Brugge, Michael B Wallace
BACKGROUND AND OBJECTIVES: Pancreatic cysts are evaluated by endoscopic ultrasound and fine needle aspiration (EUS). The only accepted treatment is pancreatectomy, which is associated with morbidity and mortality. This study evaluated the optimal thermal dosimetry of a novel radiofrequency ablation device using a standard electrosurgical unit in ex vivo cyst models. METHODS: A modified EUS 22-gauge monopolar needle prototype with a tip electrode connected to a standard electrosurgical unit (Erbe USA, Marietta, GA, USA) was used to induce a subboiling point temperature...
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28440007/spectrophotometric-analysis-of-fluorescent-zirconia-abutments-compared-to-conventional-zirconia-abutments-a-within-subject-controlled-clinical-trial
#15
Daniel S Thoma, Felix B Gamper, Vítor M Sapata, Giuseppe Voce, Christoph H F Hämmerle, Irena Sailer
BACKGROUND: Zirconia abutments are frequently used for implant-supported single crowns. Even though demonstrating esthetic benefits compared to metal abutments, zirconia abutments lead to an increased brightness of the peri-implant mucosa compared to natural teeth and are not ideal from an esthetic point of view. PURPOSE: To test whether or not a fluorescent hybrid zirconia abutment offers superior esthetics compared to a non-fluorescent one-piece zirconia abutment based on spectrophotometric analysis...
April 24, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28430334/chondro-keratoprosthesis-an-alternative-to-ookp
#16
Louis Hoffart, Laurent Guyot
PURPOSE: To evaluate the use of cartilage as a potential graft material toward osteo-odontal tissue replacement in keratoprosthesis surgery. METHODS: We describe a modification of the osteo-odonto-keratoprosthesis surgery that involves the use of autologous auricular conchal cartilage graft (ACCG). In stage 1a, a full-thickness cheek mucosa graft was performed over the ocular surface. In stage 1b, ACCG was harvested via a retroauricular approach. An optical polymethyl-methacrylate cylinder was embedded into a double-layered fragment of cartilage and secured by cyanoacrylate glue...
April 4, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28424911/long-term-outcomes-of-endoscopic-resection-of-gastric-gists
#17
Changji Yu, Guobin Liao, Chaoqiang Fan, Jing Yu, Xubiao Nie, Shiming Yang, Jianying Bai
OBJECTIVE: Although the endoscopic treatment of gastric stromal tumors is a recently accepted therapy, the long-term outcomes of this approach remain unknown. The aims of this study were to assess the long-term effectiveness and safety of endoscopic resection for gastric GISTs. METHODS: A total of 60 consecutive patients undergoing endoscopic resection of gastric GISTs were enrolled in a retrospective single-center study. Clinical data, perioperative complications, histopathologic characteristics of the tumors, and long-term outcomes were recorded...
April 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28421421/sphenoid-sinus-mucosal-thickening-in-the-acute-phase-of-pituitary-apoplexy
#18
Mueez Waqar, Robert McCreary, Tara Kearney, Konstantina Karabatsou, Kanna K Gnanalingham
PURPOSE: In pituitary apoplexy (PA), there are preliminary reports on the appearance of sphenoid sinus mucosal thickening (SSMT). SSMT is otherwise uncommon with an incidence of up to 7% in asymptomatic individuals. The aim of this study was to evaluate the incidence and clinical significance of SSMT in patients with PA and a control group of surgically treated non-functioning pituitary adenomas (NFPAs). METHODS: Retrospective review of clinical and imaging variables in PA and NFPA patients...
April 18, 2017: Pituitary
https://www.readbyqxmd.com/read/28400698/laparoscopic-rectopexy-with-urinary-bladder-xenograft-reinforcement
#19
Aradhana Mehta, Rami Afshar, David L Warner, Amy Gardner, Ellen Ackerman, Jared Brandt, Kent C Sasse
BACKGROUND AND OBJECTIVES: Rectal prolapse is often repaired laparoscopically, frequently with the use of reinforcement material. Both synthetic and biologically derived materials reduce recurrence rate compared to primary suture repair. Synthetic mesh introduces potential complications such as mesh erosion, fibrosis, and infection. Urinary bladder matrix (UBM) represents a biologically derived material for reinforcement of rectal prolapse repair with the potential to improve durability without risks of synthetic materials...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28385296/17%C3%AE-estradiol-prevents-mesenteric-injury-induced-by-occlusion-of-the-proximal-descending-aorta-in-male-rats
#20
Paulo Thales Rocha de Sousa, Ana Cristina Breithaupt-Faloppa, Cristiano de Jesus Correia, Raif Restivo Simão, Sueli Gomes Ferreira, Alfredo Inácio Fiorelli, Luiz Felipe Pinho Moreira, Paulina Sannomiya
OBJECTIVE: In surgical aortic repair or cardiac surgery with aorta occlusion, the occurrence of mesenteric ischemia and bowel injury has been associated with higher short-term mortality. The vascular protection of estrogens has been investigated and is mainly mediated by increasing the availability of nitric oxide (NO). Therefore, this study investigated the role of 17β-estradiol on visceral ischemia-reperfusion (I/R) injury after descending aorta occlusion in male rats. METHODS: Mesenteric ischemia was induced in male Wistar rats by placing a 2F Fogarty arterial embolectomy catheter (Edwards Lifesciences, Irvine, Calif) in the descending aorta, which remained occluded for 15 minutes, followed by reperfusion for up to 2 hours...
April 3, 2017: Journal of Vascular Surgery
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