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Mehmet Emin Adin, David Mark Yousem
No abstract text is available yet for this article.
June 19, 2018: Radiology
V Schininà, F Albarello, M Cristofaro, F Di Stefano, N Fusco, G Cuzzi, S M Arend, D Goletti, E Busi Rizzi
BACKGROUND: Hepatic tuberculosis (TB) shows non-specific symptoms, and liver imaging may provide diagnostic clues. Here we describe a series of patients with hepatic TB showing characteristic radiological findings. METHODS: Single-centre retrospective evaluation of patients with hepatic TB diagnosed over a period of 16 years who underwent ultrasound, computed tomography (CT) and/or magnetic resonance imaging (MRI). Hepatic lesions were classified as miliary, nodular, serohepatic or cholangitis...
July 1, 2018: International Journal of Tuberculosis and Lung Disease
Paolo Ciancarella, Fabio Fazzari, Valentina Montano, Marco Guglielmo, Gianluca Pontone
A 21 year old male with no relevant medical history presented to our Institution for further assessments of a right paracardiac mass founded on a chest X-ray. Chest computed tomography revealed a wide median defect of the diaphragm at the level of xiphoid process of the sternum, with the herniation of omental fat tissue in the mediastinum. Cardiac magnetic resonance confirmed the presence of a huge hernia originating from the foramen of Morgagni (sterno-costal hiatus), displacing the heart leftwards and posteriorly and compressing the right ventricle (RV), giving to it a tubular shape...
April 2018: Journal of the Saudi Heart Association
Jian Zheng, Hong Zhang, Chun Wang
BACKGROUND: Intradiploic epidermoid cyst (IEC) concurrent with chronic epidural hematoma (CEDH) has never been reported in the literature. We report a unique case of IEC concurrent with anatomically close associated CEDH. CASE DESCRIPTION: A 54-year-old man presented with one week history of headache, confusion and drowsiness. Computed tomography (CT) exposed large extraaxial mixed density lesions with bone destruction and substantial mass effect in the left fronto-temporal region...
June 14, 2018: World Neurosurgery
N Dusi, V De Carlo, G Delvecchio, M Bellani, J C Soares, P Brambilla
BACKGROUND: Bipolar disorder (BD) is a severe and disabling mental illness, which is characterized by selective gray matter (GM) and white matter (WM) brain alterations, as observed by several imaging studies. However, the clinical course of the disease is uncertain and can vary across BD patients, with some having a benign course and others a severe disability. In this perspective, magnetic resonance imaging (MRI) can help identifying biological markers of worse prognosis. METHODS: The present selected review aimed at summarizing structural MRI (sMRI) studies exploring the correlation between brain morphology and features of clinical outcome, which could include treatment response, cognitive impairment and global functioning...
June 1, 2018: Journal of Affective Disorders
Kutsi Tuncer, Emine Izgi, Bahar Cankaya, Hayri Ogul, Mecit Kantarci
Osteochondroma is the most common benign bone tumor but it rarely arises from the scapula. Scapulothoracic bursitis is quite rare and osteochondroma is one of the unusual causes of this condition. Synovial chondromatosis may occur extremely uncommonly in this bursa. We reported an unusual case of scapulothoracic bursitis with synovial chondromatosis which is caused by osteochondroma. To the best of our knowledge, there is no defined chondromatosis in the scapulothoracic bursa secondary to scapular osteochondroma in the literature...
June 13, 2018: American Journal of Physical Medicine & Rehabilitation
Matteo Paoletti, Ana Bacila, Anna Pichiecchio, Lisa Maria Farina, Elisa Rognone, Riccardo Cremascoli, Simona Fanucchi, Raffaele Manni, Stefano Bastianello
Common postictal MRI findings include transient cortical T2 hyperintensity, restricted diffusion, and gyral and/or adjacent leptomeningeal contrast enhancement. In certain uncommon pathological conditions, other signal abnormalities can be present, suggesting a different underlying pathogenic mechanism. We report the case of a 66-year-old man, recently diagnosed with diabetes mellitus type 2, presenting with new-onset visual and auditory hallucinations, "absence" seizures, and repeated peaks of hyperglycaemia without hyperketonaemia or increased serum osmolarity...
June 15, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
Lorenzo Carnevale, Valentina D'Angelosante, Alessandro Landolfi, Giovanni Grillea, Giulio Selvetella, Marianna Storto, Giuseppe Lembo, Daniela Carnevale
Aims: Hypertension is one of the main risk factor for dementia. The subtle damage provoked by chronic high blood pressure in the brain is usually evidenced by conventional magnetic resonance imaging (MRI), in terms of white matter (WM) hyperintensities or cerebral atrophy. However, it is clear that by the time brain damage is visible, it may be too late hampering neurodegeneration. Aim of this study was to characterize a signature of early brain damage induced by hypertension, before the neurodegenerative injury manifests...
June 12, 2018: Cardiovascular Research
Sadanandvalli R Chandra, Rita Christopher, Mane M Daryappa, Rashmi Devaraj
Introduction: Phenyl ketonuria is an inborn error of amino acid metabolism resulting in excessive phenyl alanine levels in blood resulting in a spectrum of neurological defects. Patients and Methods: We retrospectively went through the records of patients diagnosed as Phenyl ketonuria in the last nine years in our team and patients who's data could be accessed were analyzed in detail. Details of laboratory tests, imaging clinical features, course were recorded. Observation: A total of 32 patients were identified in nine years of which data was available only for 15 patients...
January 2018: Journal of Pediatric Neurosciences
Mirian Ecay-Torres, Ainara Estanga, Mikel Tainta, Andrea Izagirre, Maite Garcia-Sebastian, Jorge Villanua, Montserrat Clerigue, Ane Iriondo, Iratxe Urreta, Arantzazu Arrospide, Carmen Díaz-Mardomingo, Miia Kivipelto, Pablo Martinez-Lage
OBJECTIVE: To investigate the cognitive profile of healthy individuals with increased Cardiovascular Risk Factors, Aging and Dementia (CAIDE) dementia risk score and to explore whether this association is related to vascular burden and CSF biomarkers of amyloidosis and neurodegeneration. METHOD: Cognitively normal participants (mean age 57.6 years) from the Gipuzkoa Alzheimer Project study were classified as having high risk (HR; n = 82) or low risk (LR; n = 293) for dementia according to a CAIDE score cutoff of 9...
June 13, 2018: Neurology
Yue Liu, Nady Braidy, Anne Poljak, Daniel Ky Chan, Perminder Sachdev
BACKGROUND: Cerebral small vessel disease (CSVD) comprises a variety of disorders affecting small arteries and microvessels of the brain, manifesting as white matter hyperintensities (WMHs), cerebral microbleeds (CMBs), and deep brain infarcts. In addition to its contribution to vascular dementia (VaD), it has also been suggested to contribute to the pathogenesis of Alzheimer's disease (AD). METHOD: A systematic review of the literature available on Medline, Embase and Pubmed was undertaken, whereby CSVD was divided into WMHs, CMBs and deep brain infarcts...
June 10, 2018: Ageing Research Reviews
Xin Xu, Yuanyuan Gao, Renyuan Liu, Lai Qian, Yan Chen, Xiaoying Wang, Yun Xu
Both white matter hyperintensities (WMHs) and lacunar infarctions (LIs) are magnetic resonance imaging (MRI) markers of cerebral small vessel disease (SVD). However, the association between WMH and LI remains unclear. In this study, we asked whether WMH progression is related to LI occurrence using retrospective data. Overall, 8475 WMH patients with at least two MRI images were screened, and 187 patients were included in the final study; 76 patients had WMH with LI (WL), and 111 patients had WMH without LI (WOL)...
June 2018: Aging and Disease
M Kawaguchi, H Kato, Y Hatano, N Mizuno, T Furui, K Morishige, A Hara, S Goshima, M Matsuo
AIM: To perform radiology-pathology correlation of the inchworm sign on diffusion-weighted imaging (DWI) in patients with endometrial cancer. MATERIALS AND METHODS: Consecutive patients (345) with histopathologically proven endometrial cancer who underwent preoperative magnetic resonance imaging (MRI), including DWI images, and hysterectomy were included in the present study. The inchworm sign was defined as a hypointense stalk between hyperintense endometrial cancer and hypointense myometrium on DWI images...
June 9, 2018: Clinical Radiology
Erkan Acar, Zeynep Ozdemir, Hatem Hakan Selcuk, Eda Coban, Aysun Soysal
Atrial myxoma is a rare cause of stroke. In this report we present the case of a 52-year-old female patient who went to hospital suffering from a headache. Her neurological examination was normal except for a positive Babinski sign on the left. In the superolateral of the right, a Sylvian fissure consistent with a thrombosed aneurysm was detected using computerised tomography (CT). Diffusion MRI showed an acute infarction on the right MCA area. Transthorasic Echocardiography and ECG were normal. A -16×4 mm-sized fusiform perpendicular aneurysm on the M2 segment Sylvian curve of right MCA and a -6×4 mm-sized dissecting aneurysm on P3 segment of the left posterior cerebral artery (PCA) were observed in cerebral angiography...
March 30, 2018: Ideggyógyászati Szemle
Nicola M Payton, Grégoria Kalpouzos, Debora Rizzuto, Laura Fratiglioni, Miia Kivipelto, Lars Bäckman, Erika J Laukka
BACKGROUND: Cognitive and biological markers have shown varying degrees of success in identifying persons who will develop dementia. OBJECTIVE: To evaluate different combinations of cognitive and biological markers and identify prediction models with the highest accuracy for identifying persons with increased dementia risk. METHODS: Neuropsychological assessment, genetic testing (apolipoprotein E -APOE), and structural magnetic resonance imaging (MRI) were performed for 418 older individuals without dementia (60-97 years) from a population-based study (SNAC-K)...
June 4, 2018: Journal of Alzheimer's Disease: JAD
Sung Bin Park, Min-Jeong Kim, Kyoung Ho Lee, Yousun Ko
OBJECTIVE: To retrospectively evaluate the clinical, pathological, and imaging features of ovarian serous surface papillary borderline tumors (SSPBTs). METHODS: Imaging features were analyzed, including the tumor size, laterality, tumor spread and the presence of ascites. Morphological nature (encased normal ovary, characteristics on MRI) and contrast enhancement (increased flow on Doppler US) were also evaluated. Clinical and pathological features, such as tumor markers (CA 125), treatment methods, outcomes on follow-up, and surgical staging, were analyzed...
June 11, 2018: British Journal of Radiology
Mohamed Badri, Ghassen Gader, Kamel Bahri, Ihsen Zammel
Background: Intracranial dermoid cysts are uncommon lesions with characteristic imaging appearances. Symptomatic clinical presentation usually occurs in one of two ways: mass effect or rupture. Radiologically, dermoid cysts typically present as low density masses on computed tomography (CT) scan and are generally hyperintense on T1-weighted magnetic resonance imaging (MRI) sequences with variable signal on T2-weighted sequences. Case Description: We present the case of a 35-year-old female presented with symptoms of increased intracranial pressure...
2018: Surgical Neurology International
Deborah A Hall, Avram Fraint, Rima Dafer
Background: Fragile-X associated tremor/ataxia syndrome (FXTAS) is commonly associated with T2 hyperintensity in the middle cerebellar peduncles (MCP) on magnetic resonance imaging (MRI). However, ischemic stroke in the MCP in a patient with FXTAS has not previously been described. Case Description: A 61-year-old man with hypertension, sleep apnea, obesity, and FXTAS presented to the emergency department with 2 days of worsening balance and nausea which began 2 days after chiropractic neck manipulation. Examination revealed new nystagmus and worsening dysmetria...
2018: Frontiers in Genetics
Nidhi Prabhakar, Chirag K Ahuja, Niranjan Khandelwal
Bilateral basal ganglia lesions are a common non-specific finding seen in many diseases. One of the differential diagnoses for it, in a child, is kernicterus occurring due to hyperbilirubinemia. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common cause of severe hyperbilirubinemia. A 1-year old child presented to the hospital with history of generalized dystonia in the previous 3 days. MRI showed evidence of symmetrical lesions in bilateral globus pallidus, which were hyperintense on T2/FLAIR and isointense on T1...
April 2018: Annals of Neurosciences
Marco Duering, Marek J Konieczny, Steffen Tiedt, Ebru Baykara, Anil Man Tuladhar, Esther van Leijsen, Philippe Lyrer, Stefan T Engelter, Benno Gesierich, Melanie Achmüller, Christian Barro, Ruth Adam, Michael Ewers, Martin Dichgans, Jens Kuhle, Frank-Erik de Leeuw, Nils Peters
BACKGROUND AND PURPOSE: Neurofilament light chain (NfL) is a blood marker for neuroaxonal damage. We assessed the association between serum NfL and cerebral small vessel disease (SVD), which is highly prevalent in elderly individuals and a major cause of stroke and vascular cognitive impairment. METHODS: Using a cross-sectional design, we studied 53 and 439 patients with genetically defined SVD (Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy [CADASIL]) and sporadic SVD, respectively, as well as 93 healthy controls...
May 2018: Journal of Stroke
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