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https://www.readbyqxmd.com/read/28717201/cognitive-brain-responses-during-circadian-wake-promotion-evidence-for-sleep-pressure-dependent-hypothalamic-activations
#1
Carolin F Reichert, Micheline Maire, Virginie Gabel, Antoine U Viola, Thomas Götz, Klaus Scheffler, Markus Klarhöfer, Christian Berthomier, Werner Strobel, Christophe Phillips, Eric Salmon, Christian Cajochen, Christina Schmidt
The two-process model of sleep-wake regulation posits that sleep-wake-dependent homeostatic processes interact with the circadian timing system to affect human behavior. The circadian timing system is fundamental to maintaining stable cognitive performance, as it counteracts growing homeostatic sleep pressure during daytime. Using magnetic resonance imaging, we explored brain responses underlying working memory performance during the time of maximal circadian wake-promotion under varying sleep pressure conditions...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28714081/combining-two-model-systems-of-psychosis-the-effects-of-schizotypy-and-sleep-deprivation-on-oculomotor-control-and-psychotomimetic-states
#2
Inga Meyhöfer, Maria Steffens, Eliana Faiola, Anna-Maria Kasparbauer, Veena Kumari, Ulrich Ettinger
Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. Schizophrenia patients, high schizotypes, and sleep-deprived subjects are known to share deficits in oculomotor biomarkers. Here, we aimed to further validate the schizotypy and sleep deprivation models and investigated, for the first time, their interactive effects on smooth pursuit eye movements (SPEM), prosaccades, antisaccades, predictive saccades, and measures of psychotomimetic states, anxiety, depression, and stress...
July 17, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28713258/relationship-of-topology-multiscale-phase-synchronization-and-state-transitions-in-human-brain-networks
#3
Minkyung Kim, Seunghwan Kim, George A Mashour, UnCheol Lee
How the brain reconstitutes consciousness and cognition after a major perturbation like general anesthesia is an important question with significant neuroscientific and clinical implications. Recent empirical studies in animals and humans suggest that the recovery of consciousness after anesthesia is not random but ordered. Emergence patterns have been classified as progressive and abrupt transitions from anesthesia to consciousness, with associated differences in duration and electroencephalogram (EEG) properties...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28712995/investigations-into-within-and-between-subject-resting-state-amplitude-variations
#4
Janine Bijsterbosch, Samuel Harrison, Eugene Duff, Fidel Alfaro-Almagro, Mark Woolrich, Stephen Smith
The amplitudes of spontaneous fluctuations in brain activity may be a significant source of within-subject and between-subject variability, and this variability is likely to be carried through into functional connectivity (FC) estimates (whether directly or indirectly). Therefore, improving our understanding of amplitude fluctuations over the course of a resting state scan and variation in amplitude across individuals is of great relevance to the interpretation of FC findings. We investigate resting state amplitudes in two large-scale studies (HCP and UK Biobank), with the aim of determining between-subject and within-subject variability...
July 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28712431/the-mediating-role-of-sleep-related-metacognitive-processes-in-trait-and-pre-sleep-state-hyperarousal-in-insomnia-disorder
#5
Laura Palagini, Jason C Ong, Dieter Riemann
OBJECTIVE: Trait predisposition to hyperarousal and pre-sleep state hyperarousal are considered key factors in insomnia, but research also supports the role of cognitive and metacognitive processes. Therefore, the aim of this study was to evaluate the relationship between unhelpful sleep-related beliefs, sleep-related metacognition and trait/pre-sleep state arousal in insomnia disorder. METHOD: Sixty-eight subjects with insomnia disorder (DSM-5) and 36 good sleepers were evaluated with a set of questionnaires that included Dysfunctional Beliefs about Sleep scale (DBAS), Metacognitions Questionnaire - Insomnia (MCQI), Arousal Predisposition Scale (APS), and Pre-sleep Arousal Scale (PSAS)...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28711192/predictors-of-anxiety-in-early-stage-parkinson-s-disease-results-from-the-first-two-years-of-a-prospective-cohort-study
#6
Sonja Rutten, Peter M van der Ven, Daniel Weintraub, Gregory M Pontone, Albert F G Leentjens, Henk W Berendse, Ysbrand D van der Werf, Odile A van den Heuvel
AIM: Anxiety has a negative impact on daily functioning and quality of life in patients with Parkinson's disease (PD). This study aims at assessing which sociodemographic and clinical characteristics predict the course of anxiety in early PD. METHODS: The participants of this two-year prospective cohort study were recently diagnosed PD patients not receiving psychiatric medications or dopamine replacement therapy at baseline. Assessments were performed annually after baseline...
July 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28710215/a-study-protocol-for-an-observational-cohort-investigating-cognitive-outcomes-and-wellness-in-survivors-of-critical-illness-the-cogwell-study
#7
M Elizabeth Wilcox, Andrew S Lim, Mary P McAndrews, Richard A Wennberg, Ruxandra L Pinto, Sandra E Black, Karolina D Walczak, Jan O Friedrich, Michael S Taglione, Gordon D Rubenfeld
INTRODUCTION: Up to 9 out of 10 intensive care unit (ICU) survivors will suffer some degree of cognitive impairment at hospital discharge and approximately half will have decrements that persist for years. The mechanisms for this newly acquired brain injury are poorly understood. The purpose of this study is to describe the prevalence of sleep abnormalities and their association with cognitive impairment, examine a well-known genetic risk factor for dementia (Apolipoprotein E ε4) that may allow for genetic risk stratification of ICU survivors at greatest risk of cognitive impairment and determine if electroencephalography (EEG) is an independent predictor of long-term cognitive impairment and possibly a candidate intermediate end point for future clinical trials...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709508/the-national-sleep-foundation-s-sleep-health-index
#8
Kristen L Knutson, Julie Phelan, Michael J Paskow, Anita Roach, Kaitlyn Whiton, Gary Langer, D Sunshine Hillygus, Michael Mokrzycki, William A Broughton, Sudhansu Chokroverty, Kenneth L Lichstein, Terri E Weaver, Max Hirshkowitz
OBJECTIVES: A validated survey instrument to assess general sleep health would be a useful research tool, particularly when objective measures of sleep are not feasible. Thus, the National Sleep Foundation spearheaded the development of the Sleep Health Index (SHI). DESIGN: The development of the SHI began with a task force of experts who identified key sleep domains and questions. An initial draft of the survey was created and questions were refined using cognitive testing and pretesting...
August 2017: Sleep Health
https://www.readbyqxmd.com/read/28708737/factors-associated-with-sexual-health-and-well-being-in-older-adulthood
#9
Maria Kleinstäuber
PURPOSE OF REVIEW: To provide an update of recent studies on factors associated with sexual well being in older people with a special focus on sexual activity, satisfaction and function. RECENT FINDINGS: Most recent studies confirmed the relationship between mental health status, especially negative affect and depressive symptoms, and sexual health in older adulthood. However, when this relationship is investigated more deeply, it seems that in fact positive psychological well being (positive affect and quality of life) accounts for sexual activity rather than the lack of depressive symptoms...
July 13, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28708425/reference-values-for-the-pediatric-quality-of-life-inventory-and-the-multidimensional-fatigue-scale-in-adolescent-athletes-by-sport-and-sex
#10
Alison R Snyder Valier, Cailee E Welch Bacon, R Curtis Bay, Eileen Molzen, Kenneth C Lam, Tamara C Valovich McLeod
BACKGROUND: Effective use of patient-rated outcome measures to facilitate optimal patient care requires an understanding of the reference values of these measures within the population of interest. Little is known about reference values for commonly used patient-rated outcome measures in adolescent athletes. PURPOSE: To determine reference values for the Pediatric Quality of Life Inventory (PedsQL) and the Multidimensional Fatigue Scale (MFS) in adolescent athletes by sport and sex...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28707310/sleep-deprivation-in-interventional-cardiology-implications-for-patient-care-and-physician-health
#11
Yader Sandoval, Angie S Lobo, Virend K Somers, Kenneth Rosenfield, Steven M Bradley, Paul Sorajja, Peter Tajti, Emmanouil S Brilakis
The burden and impact of sleep deprivation on both patient care and on the health of interventional cardiologists is not well understood. Due to the nature of emergent procedures occurring in the cardiac catheterization laboratory, interventionalists are prone to suffer from acute and/or chronic sleep deprivation. Sleep deprivation has been associated with numerous adverse effects, such as impaired performance, cognitive deficits, reduced psychomotor vigilance, and workplace errors and injuries, among many others...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28701732/alpha-power-predicts-persistence-of-bistable-perception
#12
Giovanni Piantoni, Nico Romeijn, German Gomez-Herrero, Ysbrand D Van Der Werf, Eus J W Van Someren
Perception is strongly affected by the intrinsic state of the brain, which controls the propensity to either maintain a particular perceptual interpretation or switch to another. To understand the mechanisms underlying the spontaneous drive of the brain to explore alternative interpretations of unchanging stimuli, we repeatedly recorded high-density EEG after normal sleep and after sleep deprivation while participants observed a Necker cube image and reported the durations of the alternating representations of their bistable perception...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28700954/cognitive-and-motor-reaction-times-in-obstructive-sleep-apnea-syndrome-a-study-based-on-computerized-measures
#13
Maria Devita, Sonia Montemurro, Andrea Zangrossi, Sara Ramponi, Maurizio Marvisi, Daniele Villani, Maria Clara Raimondi, Paola Merlo, Maria Luisa Rusconi, Sara Mondini
Obstructive Sleep Apnea Syndrome (OSAS) is mainly associated with executive dysfunction. Although delayed reaction times (RTs) in patients with OSAS have been reported, sensitivity of processing speed has not been adequately assessed. This study suggests sensitive and reliable measures to clarify whether different components of information processing speed, i.e. cognitive and motor responses, are equally impaired in OSAS. Thirty-three patients with OSAS were compared with thirty healthy controls. The MoCA test was administered to assess participants' global neuropsychological profile...
July 9, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28699777/caring-for-an-individual-with-mild-cognitive-impairment-a-qualitative-perspective-of-health-related-quality-of-life-from-caregivers
#14
Noelle E Carlozzi, Carey W Sherman, Kaley Angers, Mitchell P Belanger, Amy M Austin, Kelly A Ryan
OBJECTIVES: Little is known regarding the effect that caring for an individual with Mild Cognitive Impairment (MCI) has on health-related quality of life (HRQOL). We sought to identify the most important aspects of HRQOL related to caring for an individual with MCI. METHODS: Six focus groups were conducted with caregivers of individuals with MCI (n = 32). Qualitative frequency analysis was used to analyze the data. RESULTS: Findings indicated that caregivers most frequently discussed social health, including changes in social roles and an increased need for social support (51...
July 12, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28697489/subjective-sleep-disturbance-in-chinese-adults-with-epilepsy-associations-with-affective-symptoms
#15
Yeru Shen, Mengmeng Zhang, Yu Wang, Lanlan Wang, Xiangjun Xu, Gairong Xiao, Jing Chen, Ting Zhang, Nong Zhou
BACKGROUND: As well as being a very common neurological disease worldwide, epilepsy significantly impairs patients' emotional, behavioral, and cognitive functioning. Sleep disturbances are the most frequent complaint in patients with epilepsy. The present study assesses the impact of a range of affective symptoms on subjective sleep quality and sleep disturbances in Chinese adults with epilepsy. METHODS: Adults with epilepsy who visited our epilepsy clinic from July 2015 to March 2016 were enrolled in our study...
July 1, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28695399/the-long-term-effects-of-mandibular-advancement-splint-on-cardiovascular-fitness-and-psychomotor-performance-in-patients-with-mild-to-moderate-obstructive-sleep-apnea-a-prospective-study
#16
Ashutosh Gupta, Arvind Tripathi, Piyush Sharma
BACKGROUND: Obstructive sleep apnea (OSA) manifests as a reduction or complete cessation of airflow despite an ongoing inspiratory effort, leading to hypoxemia and hypercapnia. The inability to maintain normal breathing reduces the oxygen saturation in blood leading to a cycle of various systemic implications. Hence, a prospective single arm study was planned to evaluate the long-term (2 years) effect of oral appliance on cardiovascular fitness and psychomotor performance in patients with mild to moderate obstructive sleep apnea...
July 10, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28694772/connexin-dependent-neuroglial-networking-as-a-new-therapeutic-target
#17
REVIEW
Mathieu Charvériat, Christian C Naus, Luc Leybaert, Juan C Sáez, Christian Giaume
Astrocytes and neurons dynamically interact during physiological processes, and it is now widely accepted that they are both organized in plastic and tightly regulated networks. Astrocytes are connected through connexin-based gap junction channels, with brain region specificities, and those networks modulate neuronal activities, such as those involved in sleep-wake cycle, cognitive, or sensory functions. Additionally, astrocyte domains have been involved in neurogenesis and neuronal differentiation during development; they participate in the "tripartite synapse" with both pre-synaptic and post-synaptic neurons by tuning down or up neuronal activities through the control of neuronal synaptic strength...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28686520/mindfulness-based-interventions-for-women-with-breast-cancer-an-updated-systematic-review-and-meta-analysis
#18
Heidemarie Haller, María M Winkler, Petra Klose, Gustav Dobos, Sherko Kümmel, Holger Cramer
BACKGROUND: The aim of this meta-analysis was to systematically update the evidence for mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) in women with breast cancer. MATERIAL AND METHODS: In October 2016, PubMed, Scopus, and Central were searched for randomized controlled trials on MBSR/MBCT in breast cancer patients. The primary outcome was health-related quality of life. Secondary outcomes were fatigue, sleep stress, depression, anxiety, and safety...
July 7, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28684245/assessment-of-neuroinflammation-in-patients-with-idiopathic-rapid-eye-movement-sleep-behaviour-disorder-a-case-control-study
#19
Morten Gersel Stokholm, Alex Iranzo, Karen Østergaard, Mónica Serradell, Marit Otto, Kristina Bacher Svendsen, Alicia Garrido, Dolores Vilas, Per Borghammer, Joan Santamaria, Arne Møller, Carles Gaig, David J Brooks, Eduardo Tolosa, Nicola Pavese
BACKGROUND: Findings from longitudinal follow-up studies in patients with idiopathic rapid-eye-movement sleep behaviour disorder (IRBD) have shown that most patients will eventually develop the synucleinopathies Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy. Neuroinflammation in the form of microglial activation is present in synucleinopathies and is a potential therapeutic target to halt or delay the neurodegenerative process. We aimed to investigate whether neuroinflammation is present in patients with IRBD and its possible relation to nigrostriatal dopamine function...
July 3, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28683833/effectiveness-of-skin-to-skin-contact-versus-care-as-usual-in-mothers-and-their-full-term-infants-study-protocol-for-a-parallel-group-randomized-controlled-trial
#20
Kelly H M Cooijmans, Roseriet Beijers, Anne C Rovers, Carolina de Weerth
BACKGROUND: Twenty-to-forty percent of women experience postpartum depressive symptoms, which can affect both the mother and infant. In preterm infants, daily skin-to-skin contact (SSC) between the mother and her infant has been shown to decrease maternal postpartum depressive symptoms. In full-term infants, only two studies investigated SSC effects on maternal depressive symptoms and found similar results. Research in preterm infants also showed that SSC improves other mental and physical health outcomes of the mother and the infant, and improves the quality of mother-infant relationship...
July 6, 2017: BMC Pediatrics
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