keyword
https://read.qxmd.com/read/38537227/presentation-of-wernicke-encephalopathy-in-patient-secondary-to-one-anastomosis-gastric-bypass-case-report-and-literature-review
#1
JOURNAL ARTICLE
Luis F Zorrilla-Núñez, Luis Tamez-Pedroza, Patricio Durán-Moreno, Gerardo E Muñoz-Maldonado
Wernicke encephalopathy, which is caused by a thiamine deficiency, occurs in 0.8-2% of the population. Only 16% present the typical triad of this disease: nystagmus, confusion and ataxia. We present the case of a postoperative patient with a one anastomosis gastric bypass with reoperation undergoing a Roux-en-Y gastric bypass that begins with confusion and nystagmus on her third postoperative day. The diagnosis of Wernicke encephalopathy is made by imaging, and vitamin B1 is administered with total improvement of nystagmus and altered state of consciousness (lethargy, bradypsychia, bradylalia)...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38493062/temperature-management-in-acute-brain-injury-a-narrative-review
#2
REVIEW
Eva Esther Tejerina Álvarez, José Ángel Lorente Balanza
Temperature management has been used in patients with acute brain injury resulting from different conditions, such as post-cardiac arrest hypoxic-ischaemic insult, acute ischaemic stroke, and severe traumatic brain injury. However, current evidence offers inconsistent and often contradictory results regarding the clinical benefit of this therapeutic strategy on mortality and functional outcomes. Current guidelines have focused mainly on active prevention and treatment of fever, while therapeutic hypothermia (TH) has fallen into disuse, although doubts persist as to its effectiveness according to the method of application and appropriate patient selection...
March 15, 2024: Medicina intensiva
https://read.qxmd.com/read/38452930/venous-congestive-encephalopathy-secondary-to-arteriovenous-fistula-aggravated-by-cerebrospinal-fluid-shunt
#3
Juan Casado Pellejero, Silvia Vázquez Sufuentes, Laura Beatriz López López, Rosario Barrena Caballo
We present a unique clinical case of venous congestive encephalopathy in the context of a cerebral arteriovenous fistula with clinical worsening secondary to valvular overdrainage. ICP monitoring, the different pressure settings of the programable CSF shunt and the detailed clinical description that is carried out offer us enough data to understand that this case provides important pathophysiological knowledge to a little-known disease.
March 5, 2024: Neurocirugía (English Edition)
https://read.qxmd.com/read/38331678/motor-cognitive-and-behavioural-outcomes-after-neonatal-hypoxic-ischaemic-encephalopathy
#4
JOURNAL ARTICLE
María Montesclaros Hortigüela, Miriam Martínez-Biarge, David Conejo, Cristina Vega-Del-Val, Juan Arnaez
INTRODUCTION: The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift of severe pathology towards mild motor disorders and emotional problems. The aim of this study was to analyse neurodevelopmental outcomes in a cohort of neonates with HIE at age 3 years. PATIENTS AND METHOD: Multicentre observational study of neonates born at 35 or more weeks of gestation with moderate to severe HIE in 2011-2013 in 12 hospitals in a large Spanish region (91 217 m2 ), with the recruitment extended through 2017 in the coordinating hospital...
February 7, 2024: Anales de pediatría
https://read.qxmd.com/read/38278413/fatigue-in-patients-with-acquired-brain-damage
#5
REVIEW
A Juárez-Belaúnde, E Orcajo, S Lejarreta, P Davila-Pérez, N León, A Oliviero
Fatigue is a complex, multidimensional syndrome that is prevalent in patients with acquired brain damage and has a negative impact on the neurorehabilitation process. It presents from early stages after the injury, and may persist over time, regardless of whether sequelae have resolved. Fatigue is conditioned by upper neuronal circuits, and is defined as an abnormal perception of overexertion. Its prevalence ranges from 29% to 77% after stroke, from 18% to 75% after traumatic brain injury, and from 47% to 97% after brain tumours...
January 24, 2024: Neurología
https://read.qxmd.com/read/37827820/steroid-responsive-encephalopathy-associated-with-autoimmune-thyroiditis-as-a-cause-of-acuteencephalopathy
#6
JOURNAL ARTICLE
Milan Maretta, Alexandra Lacková, Hedviga Wagnerová, Eva Feketeová, Zuzana Gdovinová
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), known as Hashimoto's encephalopathy (HE), represents a heterogeneous group of neurological and neuropsychiatric symptoms associated with a presence of antithyroid antibodies in case of other causes of encephalopathy were excluded. Clinical symptoms most commonly includes acute onset of encephalopathy, behaviour changes and cognitive dysfunction, epileptic seizures as well as cerebellar and extrapyramidal symptoms. Corticoids provides rapid and sustained therapeutic benefit in most patients and only a few patients require other immunosuppressive therapy such as plasmapheresis, intravenous immunoglobulins, or others...
2023: Vnitr̆ní Lékar̆ství
https://read.qxmd.com/read/37740612/preocupaciones-sobre-la-atenci%C3%A3-n-sanitaria-en-progenitores-de-ni%C3%A3-os-con-diferentes-encefalopat%C3%A3-as-epil%C3%A3-pticas-gen%C3%A3-ticas-del-desarrollo-un-estudio-cualitativo
#7
JOURNAL ARTICLE
Domingo Palacios-Ceña, Javier Güeita-Rodríguez, Antonio Gil-Nagel, Carmen Jimenez-Antona, Cristina García-Bravo, Juan Francisco Velarde-García, Juan Nicolas Cuenca-Zaldivar, Ángel Aledo-Serrano
No abstract text is available yet for this article.
September 23, 2023: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/37714125/-developmental-and-epileptic-encephalopathy-what-is-new
#8
REVIEW
Jorge Vidaurre
It is not the intend of this article to present a detailed description of each developmental and epileptic encephalopathy, but to discuss recent changes in the terminology and diagnostic criteria of specific disorders, based on an updated review of the last 10 years. Important changes in the definitions of specific syndromes and new treatments that have shown efficacy in the management of seizures in these patients are analyzed. In conclusion: New gene modulation therapy will likely improve not only seizure frequency, but also cognitive outcome and therefore quality of life...
September 2023: Medicina
https://read.qxmd.com/read/37714119/-neonatal-hypoxic-ischemic-encephalopathy-progress-and-new-treatments-according-to-the-pathophysiological-basis-of-the-injury
#9
REVIEW
Edgard Andrade
Neonatal hypoxic ischemic encephalopathy (HIE) is a type of injury caused by lack of oxygen in the brain during the neonatal period. It is a clinical syndrome clearly recognizable in term and premature newborns secondary to asphyxia at the time of delivery. HIE is estimated to occur at a frequency of 1-3 for each 1000 alive newborns per year in developed countries. In countries of low or medium income, the incidence is up to 10-20 times higher, equivalent to 1-8 alive newborns per each 1000. The social and economic impact has been estimated near US$ 50...
September 2023: Medicina
https://read.qxmd.com/read/37647908/nonalcoholic-wernicke-encephalopathy-with-petechial-hemorrhage-in-the-tectal-region
#10
JOURNAL ARTICLE
Gabriel de Deus Vieira, Augusto Celso Scarparo Amato Filho, Alfredo Damasceno
No abstract text is available yet for this article.
August 2023: Arquivos de Neuro-psiquiatria
https://read.qxmd.com/read/37490689/clinical-and-molecular-heterogeneity-in-cdlk5-disorders
#11
JOURNAL ARTICLE
José J Vázquez-Montante, Paola Márquez-Rojo, Berenice Saavedra-Milán, Cristina Hernández-Medrano, Antonio Bravo-Oro
BACKGROUND: CDKL5 deficiency syndrome is caused by pathogenic variants in the CDKL5 gene, with a variable clinical spectrum ranging from patients with characteristics of autism spectrum disorder to early-onset epilepsy refractory to treatment. Initially, until the gene was discovered, it was considered an atypical form of Rett syndrome. This study aimed to describe the clinical and molecular heterogeneity in CDLK5 disorders among three female patients with CDKL5 pathogenic variants. CASE REPORTS: We reported three unrelated Mexican female patients evaluated for global developmental delay and epilepsy...
2023: Boletín Médico del Hospital Infantil de México
https://read.qxmd.com/read/37487550/anti-inflammatory-strategies-for-hepatic-encephalopathy-preclinical-studies
#12
JOURNAL ARTICLE
Rafaela Pinto Coelho Santos, Eliana Cristina de Brito Toscano, Milene Alvarenga Rachid
Hepatic encephalopathy (HE) is a potentially reversible neuropsychiatric syndrome. Often, HE causes cognitive and motor dysfunctions due to an acute or chronic insufficiency of the liver or a shunting between the hepatic portal vein and systemic vasculature. Liver damage induces peripheral changes, such as in the metabolism and peripheral inflammatory responses that trigger exacerbated neuroinflammation. In experimental models, anti-inflammatory strategies have demonstrated neuroprotective effects, leading to a reduction in HE-related cognitive and motor impairments...
July 24, 2023: Arquivos de Neuro-psiquiatria
https://read.qxmd.com/read/37164809/-hypertension-as-a-common-element-of-renal-transplantation-with-pressor-kidney-and-posterior-reversible-encephalopathy-syndrome
#13
F Roca Oporto, A Luna Aguilera, G Montilla Cosano, C Andrades Gómez
Secondary arterial hypertension accounts for only 5-10% of cases of arterial hypertension, hence the importance of its clinical suspicion for diagnosis. One of the most common causes of secondary hypertension is renovascular hypertension, caused by renal hypoperfusion and activation of the renin-angiotensin-aldosterone system. In addition to arterial hypertension being one of the most prevalent cardiovascular risk factors in the population, its poor control can cause acute neurological disorders such as Posterior Reversible Leukoencephalopathy syndrome (PRES), being characteristic the appearance of visuals alterations...
May 8, 2023: Hipertensión y Riesgo Vascular
https://read.qxmd.com/read/37127462/current-vision-on-diagnosis-and-comprehensive-care-in-hepatic-encephalopathy
#14
F Higuera-de-la-Tijera, J A Velarde-Ruiz Velasco, R H Raña-Garibay, G E Castro-Narro, J M Abdo-Francis, R Moreno-Alcántar, J L Pérez-Hernández, A Torre, R Contreras-Omaña, A Cano-Contreras, M Castillo-Barradas, J Pérez-Escobar, J M Aldana-Ledesma, E Cerda-Reyes, N J Fernández-Pérez, J Meza-Cardona, N C Flores-García, M Reyes-Bastidas, J E Lira-Vera, E S García-Jiménez, D Santana-Vargas, V M Páez-Zayas, N C Chávez-Tapia, E Márquez-Guillén
The first clinical guidelines on hepatic encephalopathy were published in 2009. Almost 14 years since that first publication, numerous advances in the field of diagnosis, treatment, and special condition care have been made. Therefore, as an initiative of the Asociación Mexicana de Gastroenterología A.C., we present a current view of those aspects. The manuscript described herein was formulated by 24 experts that participated in six working groups, analyzing, discussing, and summarizing the following topics: Definition of hepatic encephalopathy; recommended classifications; epidemiologic panorama, worldwide and in Mexico; diagnostic tools; conditions that merit a differential diagnosis; treatment; and primary and secondary prophylaxis...
2023: Revista de Gastroenterología de México
https://read.qxmd.com/read/36774619/-nonalcoholic-wernicke-s-encephalopathy
#15
JOURNAL ARTICLE
Jair Nova, Sofía Quiles, Benjamín Maldonado, Sergio Herrando, Martín Dobarro, Magalí Álvarez
No abstract text is available yet for this article.
2023: Medicina
https://read.qxmd.com/read/36621570/posterior-reversible-encephalopathy-syndrome-in-critical-covid-19-patients-report-of-2-cases
#16
J J Tortajada Soler, M P Tauler Redondo, M Garví López, M B Lozano Serrano, J López-Torres López, M L Sánchez López
Posterior reversible encephalopathy syndrome is an acute neurological disorder characterized by variable symptoms and radiological images characteristic of vasogenic parietal-occipital edema. It is associated with clinical conditions such as high blood pressure, infection/sepsis, or cytotoxic/immunosuppressive drugs, among others. It is characterized pathophysiologically by endothelial damage with breakdown of blood-brain barrier, cerebral hypoperfusion, and vasogenic edema. The cases are presented on 2 critical COVID-19 patients who were admitted to pneumonia requiring mechanical ventilation and who, after removing sedation, developed acute and reversible neurological symptoms consisting of epilepsy and encephalopathy, associated with hyperintense subcortical lesions on brain magnetic resonance imaging compatible with posterior reversible encephalopathy syndrome...
January 2023: Revista española de anestesiología y reanimación
https://read.qxmd.com/read/36571524/clinical-and-genetic-study-of-developmental-and-epileptic-encephalopathy-in-argentinean-pediatric-patients
#17
JOURNAL ARTICLE
Matías Juanes, Mariana Loos, Gabriela Reyes, Gabriel Veneruzzo, Francisco Martín García, Giovanna Aschettino, Silvana Calligaris, María Eugenia Martín, María Eugenia Foncuberta, Cristina N Alonso, Roberto H Caraballo
INTRODUCTION: The aim of this study was to extend our knowledge of the genetic background of Argentinean pediatric patients with developmental and epileptic encephalopathy (DEE) applying a next generation sequencing (NGS) panel. METHODS: Thirty one patients with DEE were studied, including these phenotypes: Dravet syndrome (n:7), Dravet like syndrome (n:3), West syndrome (WS) (n:6), WS that evolved to Lennox-Gastaut syndrome (LGS) (n:4), epilepsy of infancy with migrating focal seizures (n:2), continuous spikes and waves during slow sleep evolving to LGS (n:1), LGS (n:1), myoclonic status in non-progressive encephalopathy (n:1), myoclonic atonic epilepsy (n:1), epileptic encephalopathy with multifocal spikes (n:1) and unclassified epileptic encephalopathy (n:4)...
2022: Medicina
https://read.qxmd.com/read/36535294/progressive-encephalopathy-due-to-chronic-exposure-to-lead
#18
JOURNAL ARTICLE
Bárbara Cristina Vieira de Aquino, Agábio Diógenes Pessoa Neto, Mariana Galvão de Lima Martins Freire, Emanuela Coriolano Fidelix, Paulo Santiago de Morais Brito, Manuel Moreira Neto, Rodrigo Alencar E Silva, Clécio de Oliveira Godeiro Junior
No abstract text is available yet for this article.
October 2022: Arquivos de Neuro-psiquiatria
https://read.qxmd.com/read/36440748/intranasal-disulfiram-induced-encephalopathy-clinical-and-neuroimage-findings
#19
A Matas-García, A Téllez, S Fernández, E Salgado, P Castro
INTRODUCTION: Disulfiram-induced-encephalopathy is a rare complication that has been well described in adults. Although it usually occurs in acute intoxication with high doses of disulfiram, late onset encephalopathy has also been reported. Some authors propose the inhibition of dopamine beta-hydroxylase mediated by toxic metabolites of disulfiram as the main responsible, but the exact mechanism remains unclear. The aim of this report was to describe the clinical and neuroimaging findings in an unusual case of acute encephalitis due to disulfiram toxicity associated to chronic intranasal consume...
December 1, 2022: Revista de Neurologia
https://read.qxmd.com/read/36357057/neuraxial-block-anesthetic-technique-in-a-patient-with-scn8a-encephalopathy-case-report
#20
Eric Guimar Es Machado, Isis da Rocha Costa Bill, Mariana Moraes Pereira das Neves Ara Jo, Jos Francisco Nunes Pereira das Neves, Gilson Lorena Mau S, Marco Felipe Bouzada Marcos, Fernando de Paiva Ara Jo
Mutations in SCN8A gene lead to changes in sodium channels in the brain, which are correlated with severe epileptic syndrome. Due to the rarity, there are few studies that support anesthesia in that population. The present study aims to report alternatives to inhalation anesthesia at epileptic encephalopathy. CASE REPORT: Male, 4 years old, with SCN8A encephalopathy with surgical indication of orchidopexy. Neuroaxis block was performed and dexmedetomidine was used as a pre-anesthetic and sedation. The anestheticsurgical act was uneventful...
November 2022: Brazilian Journal of Anesthesiology
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