keyword
MENU ▼
Read by QxMD icon Read
search

pregnancy related disorder

keyword
https://www.readbyqxmd.com/read/29775803/assisted-reproductive-technologies-and-imprinting-disorders-results-of-a-study-from-a-french-congenital-malformations-registry
#1
Audrey Uk, Sophie Collardeau-Frachon, Quentin Scanvion, Lucas Michon, Emmanuelle Amar
INTRODUCTION: Assisted Reproductive Technologies (ART) is increasingly used to help infertile couples to have children around the world. A number of studies have been published reporting an increased risk of major malformations in children born following ART, especially an increased incidence of epigenetic diseases (ED). This study aimed to assess the incidence of epigenetic diseases with affected imprinting genes in infants or children from pregnancies obtained through IVF/ICSI compared to infants or children from pregnancies obtained spontaneously...
May 15, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29773648/ten-eleven-translocation-2-demethylates-the-mmp9-promoter-and-its-down-regulation-in-preeclampsia-impairs-trophoblast-migration-and-invasion
#2
Xiaoliang Li, Chunlian Wu, Ying Shen, Ke Wang, Li Tang, Mi Zhou, Ming Yang, Tianying Pan, Xinghui Liu, Wenming Xu
Preeclampsia is the most common clinical disorder in pregnancy and might result from disordered uterine environments caused by epigenetic modifications, including deregulation of DNA methylation/demethylation. Recent research has indicated that 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC) via oxidation by ten-eleven translocation (TET) enzymes, is involved in DNA methylation-related plasticity. Here, we report that TET2 expression and 5hmC abundance are significantly altered in the placentas from preeclampsia patients...
May 17, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29766818/cell-free-fetal-dna-a-novel-biomarker-for-early-prediction-of-pre-eclampsia-and-other-obstetric-complications
#3
Naina Kumar, Amit Kant Singh
Hypertensive disorder of pregnancy, especially Pre-eclampsia is one of the major causes of increased maternal and perinatal morbidity and mortality all over the world. Early prediction of pre-eclampsia is the need of modern obstetrics, as this can timely prevent the progress of disease as well as related fetal and maternal morbidity and mortality. In addition to the screening of fetal aneuploidies, Rhesus-D status, fetal sex, single gene disorders, the cell-free fetal Deoxyribonucleic acid (DNA) quantification has emerged out as a promising biomarker for prediction of pre-eclampsia...
May 16, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29764405/urinary-iodine-concentration-and-thyroid-volume-of-pregnant-women-attending-antenatal-care-in-two-selected-hospitals-in-ashanti-region-ghana-a-comparative-cross-sectional-study
#4
Daniel Gyamfi, Yaw Amo Wiafe, Kwabena Owusu Danquah, Ernest Adankwah, Gertrude Akua Amissah, Angela Odame
BACKGROUND: Iodine deficiency is a major public health problem affecting people worldwide, particularly pregnant women. Iodine requirements increase substantially during pregnancy making pregnant women vulnerable to iodine deficiency and its disorders such as abortions, stillbirths and pregnancy goitre as well as congenital abnormalities, cretinism and mental retardation in their children. The primary aim of this study was to evaluate the prevalence of iodine deficiency and goitre among pregnant women attending antenatal sessions at two selected hospitals in Ashanti region, Ghana...
May 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29758115/antepartum-care-of-women-who-are-obese-during-pregnancy-systematic-review-of-the-current-evidence
#5
REVIEW
Nicole S Carlson, Sharon Lynn Leslie, Alexis Dunn
INTRODUCTION: Nearly 40% of US women of childbearing age are obese. Obesity during pregnancy is associated with multiple risks for both the woman and fetus, yet clinicians often feel unprepared to provide optimal antepartum care for this group of women. We collected and reviewed current evidence concerning antepartum care of women who are obese during pregnancy. METHODS: We conducted a systematic review using PRISMA guidelines. Current evidence relating to the pregnancy care of women with a prepregnancy body mass index of 30kg/m2 or higher was identified using MEDLINE databases via PubMed, Embase, and Web of Science Core Collection between January 2012 and February 2018...
May 14, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29756588/toward-a-shared-care-model-of-relapsing-remitting-multiple-sclerosis-role-of-the-primary-care-practitioner
#6
Jiwon Oh, Marie-Sarah Gagné-Brosseau, Melanie Guenette, Catherine Larochelle, François Lemieux, Suresh Menon, Sarah A Morrow, Laurence Poliquin-Lasnier, Chantal Roy-Hewitson, Carolina Rush, Anne-Marie Trudelle, Paul S Giacomini
The objective of this study was to develop a shared-care model to enable primary-care physicians to participate more fully in meeting the complex, multidisciplinary healthcare needs of patients with multiple sclerosis (MS). DESIGN: The design consisted of development of consensus recommendations and a shared-care algorithm. PARTICIPANTS: A working group of 11 Canadian neurologists involved in the management of patients with MS were included in this study. MAIN MESSAGE: The clinical management of patients with multiple sclerosis is increasing in complexity as new disease-modifying therapies (DMTs) become available, and ongoing safety monitoring is required...
May 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29753283/relation-of-bmi-and-weight-suppression-to-eating-pathology-in-undergraduates
#7
C Blair Burnette, Courtney C Simpson, Suzanne E Mazzeo
Weight suppression (WS), the difference in one's highest and current adult weight excluding pregnancy, is associated with eating disorder (ED) symptom onset and maintenance. There is increasing evidence that WS is related to ED symptoms in non-clinical samples, but there are no known studies examining the interaction of WS and current body mass index (BMI) in this group. History of overweight is common in those with EDs, and higher weight status often delays identification and treatment. This study examined the interaction of WS and current BMI on body dissatisfaction and eating pathology in undergraduate men and women...
May 5, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29750675/maternal-pre-pregnancy-weight-status-and-adolescent-eating-disorder-behaviors-a-longitudinal-study-of-risk-pathways
#8
Nadia Micali, Rhian M Daniel, George B Ploubidis, Bianca L De Stavola
BACKGROUND: Maternal characteristics and childhood growth have been identified as risk factors for eating disorders. Most studies to date have been unable to investigate these factors prospectively while accounting for their interdependencies. We address this by investigating whether the association of maternal pre-pregnancy body mass index (ppBMI) with adolescent eating disorder behaviors can be explained by childhood growth and/or a concurrent environmental pathway captured by maternal eating habits...
May 10, 2018: Epidemiology
https://www.readbyqxmd.com/read/29744644/an-epigenetic-association-of-malformations-adverse-reproductive-outcomes-and-fetal-origins
#9
Mark Lubinsky
VACTERL, the prototype for associated congenital anomalies, also has connections with functional issues such as pregnancy losses, prematurity, growth delays, perinatal difficulties, and parental subfertility. This segues into a broader association with similar connections even in the absence of malformations. DNA methylation disturbances in the ovum are a likely cause, with epigenetic links to individual components and to folate effects before conception, explaining diverse fetal and placental findings and providing a link to fetal origin hypothesis-related effects...
May 9, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29741798/a-pilot-rct-of-an-internet-intervention-to-reduce-the-risk-of-alcohol-exposed-pregnancy
#10
Karen Ingersoll, Christina Frederick, Kirsten MacDonnell, Lee Ritterband, Holly Lord, Brogan Jones, Lauren Truwit
BACKGROUND: Preventing alcohol-exposed pregnancies (AEPs) could reduce the incidence of fetal alcohol spectrum disorders. Previous face-to-face interventions significantly reduced risk for AEP, but a scalable intervention is needed to reach more women at risk. METHODS: This study compared a 6 Core automated, interactive, and tailored Internet intervention, the Contraception and Alcohol Risk Reduction Internet Intervention (CARRII), to a static patient education (PE) website for its effect on AEP risk...
May 9, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29739273/angiogenic-dysregulation-in-pregnancy-related-hypertension-a-role-for-metformin
#11
Nerolen Soobryan, Saravanakumar Murugesan, Arunagiri Pandiyan, Jagidesa Moodley, Irene Mackraj
In the face of escalating maternal and fetal health threats, hypertensive pregnancy disorders (HPDs) is one of the leading cause of maternal and fetal morbidity and mortality. The range of HPDs include white-coat hypertension, chronic hypertension, gestational hypertension, mild-to-moderate and severe preeclampsia and eclampsia. Current evidence implicates an imbalance of circulating anti- and angiogenic factors in HPDs emanating from the placental vasculature, impacting on angiogenesis. Delivery of the fetus is thus far the only curative measure, albeit with increased risk...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29738988/use-of-mobile-applications-and-blogs-by-pregnant-women-in-turkey-and-the-impact-on-adaptation-to-pregnancy
#12
Sultan Özkan Şat, Şengül Yaman Sözbir
OBJECTIVES: This study aimed to demonstrate how the use of mobile applications and blogs impacts on a woman's pregnancy. DESIGN: This was a descriptive study. A questionnaire and the Prenatal Self Evaluation Questionnaire (PSEQ) were administered to collect the data. The PSEQ was developed to evaluate a woman's adaptation to pregnancy before labour and contained seven subscales: acceptance of pregnancy, identification of a motherhood role, relationship with her mother, relationship with her husband, preparation for labour, prenatal fear of helplessness and loss of control in labour and concern for the well-being of self and baby...
April 11, 2018: Midwifery
https://www.readbyqxmd.com/read/29738852/altered-maternal-immune-networks-are-associated-with-adverse-child-neurodevelopment-impact-of-alcohol-consumption-during-pregnancy
#13
Tamara S Bodnar, Charlis Raineki, Wladimir Wertelecki, Lyubov Yevtushok, Larisa Plotka, Natalya Zymak-Zakutnya, Gordon Honerkamp-Smith, Alan Wells, Matthieu Rolland, Todd S Woodward, Claire D Coles, Julie A Kable, Christina D Chambers, Joanne Weinberg
Cytokines and chemokines are potent modulators of brain development and as such, dysregulation of the maternal immune system can result in deviations in the fetal cytokine balance, altering the course of typical brain development, and putting the individual on a "pathway to pathology". In the current study, we used a multi-variate approach to evaluate networks of interacting cytokines and investigated whether alterations in the maternal immune milieu could be linked to alcohol-related and alcohol-independent child neurodevelopmental delay...
May 5, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29737941/are-congenital-urinary-tract-abnormalities-linked-to-maternal-methylenetetrahydrofolate-reductase-polymorphisms-in-fetuses-of-intentionally-terminated-pregnancies-with-oligo-or-anhydramnios
#14
M Sinan Beksac, Alp Tuna Beksac, Melek Buyukeren, Atakan Tanacan, Hatice Bektas, Safak Gucer
OBJECTIVE: We aimed to evaluate fetuses of terminated pregnancies with oligo-or anhydramnios (OAH) to further investigate the association between maternal methylenetetrahydrofolate reductase (MTHFR) polymorphisms and fetal urinary tract malformations. MATERIALS AND METHODS: This retrospective study included 16 pregnancies with OAH (with normal fetal karyotype) that were intentionally terminated before 22nd gestational week. Fetal autopsy was performed in all cases...
May 8, 2018: Fetal and Pediatric Pathology
https://www.readbyqxmd.com/read/29737550/the-association-of-the-placental-caspase-3-gene-polymorphisms-and-preeclampsia-susceptibility-and-in-silico-analysis
#15
Batool Teimoori, Atefeh Yazdi, Mahnaz Rezaei, Abbas Mohammadpour-Gharehbagh, Danial Jahantigh, Saeedeh Salimi
Preeclampsia is a pathologic complication of pregnancy, associated with increased apoptosis in the cytotrophoblasts as the main cause of this disorder. Caspase-3 is a key apoptosis-related enzyme that both mitochondrial and death receptor apoptotic pathways can activate. In this study, we aimed to investigate the effect of placental CASP-3 rs4647602 and rs4647610 polymorphisms on PE susceptibility. The placentas of 106 PE women and 115 normotensive pregnant women were collected. Genomic DNA was extracted from the placenta...
May 8, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29734128/obstetric-and-perinatal-health-outcomes-related-to-schizophrenia-a-national-register-based-follow-up-study-among-finnish-women-born-between-1965-and-1980-and-their-offspring
#16
Laura Simoila, Erkki Isometsä, Mika Gissler, Jaana Suvisaari, Erja Halmesmäki, Nina Lindberg
BACKGROUND: This national register-based study assesses obstetric and perinatal health outcomes in women with schizophrenia and their offspring. METHODS: Using the Care Register for Health Care, we identified Finnish women who were born in 1965- 1980 and diagnosed with schizophrenia. For each case, five age- and place-of-birth- matched controls were obtained from the Central Population Register of Finland. They were followed from the day when the disorder was diagnosed in specialized health-care (the index day) until 31...
May 4, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29730937/familiality-of-psychiatric-disorders-and-risk-of-postpartum-psychiatric-episodes-a-population-based-cohort-study
#17
Anna E Bauer, Merete L Maegbaek, Xiaoqin Liu, Naomi R Wray, Patrick F Sullivan, William C Miller, Samantha Meltzer-Brody, Trine Munk-Olsen
OBJECTIVE: Postpartum psychiatric disorders are common and morbid complications of pregnancy. The authors sought to evaluate how family history of psychiatric disorders is associated with postpartum psychiatric disorders in proband mothers with and without a prior psychiatric history by assessing degree of relationship, type of disorder, and sex of family members. METHOD: The authors linked Danish birth and psychiatric treatment registers to evaluate familial risk of postpartum psychiatric episodes in a national population-based cohort...
May 7, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29730877/evaluation-of-the-decision-making-capacity-of-two-cases-planning-to-undergo-uterine-evacuation
#18
Ali Ercan Altınöz, Altan Eşsizoğlu, Mustafa Sercan, Didem Yiğit, Sinan Yıldız
Psychiatric disorders in the perinatal period can lead to a deterioration in one's judgment and decision-making ability. These disorders may cause sensitive and complex legal and ethical issues relating to psychiatric, obstetric, and neonatal care. Clinicians should ethically respect the autonomy of the individual, but at the same time, they must assess the individual's decision-making process with the use of forensic psychiatric and consultation-liaison psychiatric practice. While the literature related to mental disorders in pregnancy has been increasing, there is limited information regarding the medico-legal and ethical aspects of this topic...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29729708/expression-of-extracellular-matrix-and-adhesion-proteins-in-pelvic-organ-prolapse
#19
Monica Cecati, Alessandra Corradetti, Davide Sartini, Valentina Pozzi, Stefano R Giannubilo, Franca Saccucci, Andrea Ciavattini, Monica Emanuelli
Pelvic organ prolapse (POP) is a common disorder in women. It is characterized by the descent of the vaginal wall with consequent drop of pelvic organs. Pregnancy, labour and childbirth seem to be important events leading to the development of POP, since they are associated with prolonged stretch and mechanical stress of muscles, ligaments and connective tissue supporting pelvic organs. In pubocervical fascia, we explored the expression level of extracellular matrix and adhesion molecules. Tissue samples were obtained from twenty patients with POP who underwent cystocele repair, and from twenty control subjects during hysterectomy surgery...
April 30, 2018: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/29722084/the-effects-of-maternal-risk-factors-during-pregnancy-on-the-onset-of-sleep-difficulties-in-infants-at-3-months-old
#20
Isabel Morales-Muñoz, Outi Saarenpää-Heikkilä, Anneli Kylliäinen, Pirjo Pölkki, Tarja Porkka-Heiskanen, Tiina Paunio, E Juulia Paavonen
Sleep problems in young children are among the most common concerns reported to paediatricians. Sleep is thought to have important regulatory functions, and sleep difficulties in early childhood are linked to several psychosocial and physiological problems. Moreover, several prenatal factors have been found to influence infants' sleep. Among them, most of the studies have been focused on maternal prenatal depression and/or anxiety as potential risk factors for sleep problems in childhood, whereas other relevant psychological factors during pregnancy have not received as much attention...
May 2, 2018: Journal of Sleep Research
keyword
keyword
45261
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"