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https://www.readbyqxmd.com/read/28530345/-functional-somatic-syndromes-among-ethiopian-immigrants-in-israel
#1
Nimrod Grisaru, Danny Budowski, Seffefe Ayecheh, Eliezer Witztum
INTRODUCTION: The psychiatric classifications of disease (DSMIV; ICD-10) relate to a family of high incidence somatoform disorders whose use isn't uniform and cannot be measured. DSM-5 presents the term "cultural conceptualization of distress", which attempts to describe the cultural construct and its influences on mental distress and symptom presentation. Somatization among immigrants poses a diagnostic, treatment and research challenge due to cultural differences such as wrong understanding of their symptoms that may lead to misdiagnosis and to prescribing wrong and possibly harmful treatment and unnecessary hospitalization...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28528584/autism-risk-following-antidepressant-medication-during-pregnancy
#2
A Viktorin, R Uher, A Reichenberg, S Z Levine, S Sandin
BACKGROUND: Previous studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have been conflicting. METHODS: In a population-based cohort of 179 007 children born in 2006 and 2007 and followed through 2014 when aged 7 and 8, we estimated relative risks (RRs) of ASD and 95% confidence intervals (CIs) from Cox regression in children exposed to any antidepressant medication during pregnancy, and nine specific antidepressant drugs...
May 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28522560/the-effect-of-long-term-maternal-smoking-on-the-offspring-s-lung-health
#3
Suporn Sukjamnong, Yik Lung Chan, Razia Zakarya, Sonia Saad, Pawan Sharma, Rachana Santiyanont, Hui Chen, Brian G G Oliver
Maternal smoking during pregnancy contributes to long-term health problems in offspring, especially respiratory disorders which can manifest in either childhood or adulthood. Receptors for advanced glycation end-products (RAGE) are multi-ligand receptors abundantly localized in the lung, capable of responding to by-products of reactive oxygen species and pro-inflammatory responses. RAGE signalling is a key regulator of inflammation in cigarette smoking-related pulmonary diseases. However, the impact of maternal cigarette smoke exposure on lung RAGE signalling in the offspring is unclear...
May 18, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28520809/antenatal-coffee-and-tea-consumption-and-the-effect-on-birth-outcome-and-hypertensive-pregnancy-disorders
#4
Timothy van der Hoeven, Joyce L Browne, Cuno S P M Uiterwaal, Cornelis K van der Ent, Diederick E Grobbee, Geertje W Dalmeijer
BACKGROUND AND OBJECTIVE: Coffee and tea are commonly consumed during pregnancy. While several of their components, like caffeine, have strong pharmacological effects, the effect on the unborn fetus remains unclear. Caffeine intake has been associated with abortion, preterm birth and fetal growth restriction, but a general consensus on caffeine restriction is still lacking. We aimed to investigate antenatal coffee, tea and caffeine consumption and the effect on birth weight and length, gestational age at birth and hypertensive disorders in pregnancy...
2017: PloS One
https://www.readbyqxmd.com/read/28514021/an-update-systematic-review-of-fetal-death-congenital-anomalies-and-fertility-disorders-among-health-care-workers
#5
REVIEW
Charline Warembourg, Sylvaine Cordier, Ronan Garlantézec
BACKGROUND: Health care workers (HCWs) are occupationally exposed to various hazards, some associated with adverse pregnancy outcomes in previous reviews. This systematic review aims at synthesizing the recent literature on occupational exposures among HCWs related to fetal death, congenital anomalies, and fertility disorders. METHODS: We searched the Medline database from 2000 to 2015 for articles about all potential occupational exposures of women and men working in this sector...
June 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28513285/hypertensive-disorders-of-pregnancy-increase-the-risk-for-chronic-kidney-disease-a-population-based-retrospective-study
#6
Maika Oishi, Kaori Iino, Kanji Tanaka, Kana Ishihara, Yoshihito Yokoyama, Ippei Takahashi, Hideki Mizunuma
Hypertensive disorders of pregnancy (HDP) and chronic kidney disease (CKD) are well-known risk factors for cardiovascular disease (CVD) in later life. However, few studies have investigated the association of HDP with CKD. Moreover, these studies utilized either registry- or clinical-based data and did not include subclinical CKD patients. To address this gap in the literature, we investigated whether HDP is related to CKD, diagnosed based on the estimated glomerular filtration rate (eGFR), in later life. We designed a population-based, retrospective study, and reviewed the results of blood and physiological examinations as well as the results of pregnancy data available in patients' Maternity Health Record Books for 312 women...
May 17, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28511722/use-of-rapid-ascertainment-process-for-institutional-deaths-rapid-to-identify-pregnancy-related-deaths-in-tertiary-care-obstetric-hospitals-in-three-departments-in-haiti
#7
Andrew T Boyd, Erin N Hulland, Reynold Grand'Pierre, Floris Nesi, Patrice Honoré, Reginald Jean-Louis, Endang Handzel
BACKGROUND: Accurate assessment of maternal deaths is difficult in countries lacking standardized data sources for their review. As a first step to investigate suspected maternal deaths, WHO suggests surveillance of "pregnancy-related deaths", defined as deaths of women while pregnant or within 42 days of termination of pregnancy, irrespective of cause. Rapid Ascertainment Process for Institutional Deaths (RAPID), a surveillance tool, retrospectively identifies pregnancy-related deaths occurring in health facilities that may be missed by routine surveillance to assess gaps in reporting these deaths...
May 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28511458/maternal-and-cord-blood-plasma-seng-and-tgf-%C3%AE-1-in-patients-with-hypertensive-disorders-of-pregnancy-a-pilot-study-in-a-south-indian-population
#8
Vickneshwaran Vinayagam, Zachariah Bobby, Syed Habeebullah, Latha Chaturvedula, Shruthi K Bharadwaj
INTRODUCTION: Hypertensive Disorders of Pregnancy (HDP) are one of the most widespread complications of pregnancy that affects both mother and foetus. It has been observed that in Preeclampsia, the release of soluble angiogenic factors from the ischemic placenta into maternal plasma plays a crucial role in the pathogenesis. AIM: To assess the plasma Soluble Endoglin (sEng) and Transforming Growth Factor (TGF-β1) levels in various types of HDP and to correlate the levels of these markers with the pregnancy outcome...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508879/oxidative-stress-and-male-infertility
#9
REVIEW
Shilpa Bisht, Muneeb Faiq, Madhuri Tolahunase, Rima Dada
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts, and telomeres and, therefore might provide a common underlying aetiology of male infertility and recurrent pregnancy loss, in addition to congenital malformations, complex neuropsychiatric disorders, and childhood cancers in children fathered by men with defective sperm cells. Spermatozoa are highly vulnerable to oxidative stress owing to limited levels of antioxidant defence and a single, limited DNA-damage detection and repair mechanism...
May 16, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/28507767/post-traumatic-stress-in-pregnant-women-with-primary-cytomegalovirus-infection-and-risk-of-congenital-infection-in-newborns
#10
Francesco Vadini, Elisa Tracanna, Ennio Polilli, Monica Tontodonati, Elena Ricci, Francesca Santilli, Giustino Parruti
BACKGROUND: Substantial evidence indicates that perinatal mental disturbances are associated with the risk for negative maternal-newborn outcomes. A neuroendocrine brain-placenta interaction has been described to explain the association between prenatal stress-related disorders and placental abnormalities. Whether these mechanisms may affect the likelihood of mother-to-child transmission (MTCT) of infections has never been investigated. AIMS: To evaluate the role of psychological factors in cytomegalovirus (CMV) MTCT in pregnant women with primary CMV infection...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/28504561/sexual-violence-and-intimate-partner-violence-in-college-women-with-a-mental-health-and-or-behavior-disability
#11
Amy Bonomi, Emily Nichols, Rebecca Kammes, Troye Green
OBJECTIVES: We address questions about (1) how college women with a disability experience sexual violence (SV) and intimate partner violence (IPV) across partners, including disability-specific abuse and (2) how SV/IPV impacts psychological, behavioral, physical, and academic life domains. METHODS/DESIGN: Twenty-seven female college students (mean age, 21.2; 66.6% white; 66.6% heterosexual) were randomly sampled from university registrar records. To be eligible for the study, students had to have at least one experience of SV/IPV since age 18 and a disability (88...
May 15, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28501654/urinary-organophosphate-insecticide-metabolite-concentrations-during-pregnancy-and-children-s-interpersonal-communication-repetitive-and-stereotypic-behaviors-at-8-years-of-age-the-home-study
#12
Marisa E Millenson, Joseph M Braun, Antonia M Calafat, Dana Boyd Barr, Yen-Tsung Huang, Aimin Chen, Bruce P Lanphear, Kimberly Yolton
BACKGROUND: Prenatal exposure to organophosphate insecticides may be associated with autism spectrum disorders and related behaviors. This association may be modified by single nucleotide polymorphisms in the paraoxonase (PON1) enzyme. OBJECTIVE: We examined the relationship of prenatal organophosphate insecticide biomarkers with reciprocal social, repetitive, and stereotypic behaviors in 8-year old children, and modification of this relationship by child PON1 polymorphisms...
May 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28500780/prognostic-factors-of-maternal-near-miss-events-and-maternal-deaths-in-a-tertiary-healthcare-facility-in-india
#13
Tabassum Khan, Poonam Laul, Anish Laul, Mohammed Ramzan
OBJECTIVE: To study maternal near miss (MNM) and maternal mortality to identify rectifiable risk factors. METHODS: The present cross-sectional retrospective study included pregnant women who experienced acute life-threatening pregnancy-related adverse events at Deen Dayal Upadhyay hospital, New Delhi, India, between September 1, 2009, and August 31, 2011. Patient data were analyzed to investigate factors associated with MNM events and maternal deaths. RESULTS: There were 369 patients included, and 302 MNM events and 67 maternal deaths were recorded...
May 13, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28497091/restless-leg-syndrome-in-chronic-hemodialysis-patients-in-mashhad-hemodialysis-centers
#14
Niloufar Zadeh Saraji, Maryam Hami, Reza Boostani, Mohammad Javad Mojahedi
Introduction: Restless leg syndrome (RLS) is a sensory motor disorder. Patients with this syndrome have serious and uncontrollable desire to move their legs, which is mostly due to an uncomfortable feeling intensified when they are motionless. It may be a genetic disorder or secondary to iron deficiency, neurodegenerations, pregnancy, some drugs and severe kidney diseases. Objectives: This study was designed to find out the prevalence and its risk factors of RLS in hemodialysis patients. Patients and Methods: This multicenter cross-sectional study was done on 260 hemodialysis patients...
2017: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/28495514/neurobehavioral-risks-of-ssris-in-pregnancy-comparing-human-and-animal-data
#15
REVIEW
Asher Ornoy
During the last twenty years, in spite of extensive literature regarding the use of SSRIs in pregnancy, confusion still exists as to possible long-term risks of these drugs on the offspring. Possible negative effects relate to neurodevelopmental outcome and association with Autism Spectrum Disorder (ASD). Most neurodevelopmental follow up studies did not find significant cognitive impairment except from some apparently transient, gross motor delay and slight impairment of language abilities. The literature on the possible association of SSRIs with ASD is inconsistent, and if an association exists it is apparently throughout pregnancy...
May 8, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28493861/maternal-pre-pregnancy-obesity-and-neuropsychological-development-in-pre-school-children-a-prospective-cohort-study
#16
Maribel Casas, Joan Forns, David Martínez, Mònica Guxens, Ana Fernandez-Somoano, Jesus Ibarluzea, Nerea Lertxundi, Mario Murcia, Marisa Rebagliato, Adonina Tardon, Jordi Sunyer, Martine Vrijheid
BACKGROUND: Maternal pre-pregnancy obesity may impair infant neuropsychological development, but it is unclear if intrauterine or confounding factors drive this association. METHODS: We assessed whether maternal pre-pregnancy obesity was associated with neuropsychological development in 1,827 Spanish children. At 5 years, cognitive and psychomotor development was assessed using McCarthy Scales of Children's Abilities, attention deficit hyperactivity disorder (ADHD) symptoms using the Criteria of Diagnostic and Statistical Manual of Mental Disorders, and autism spectrum disorder symptoms using the Childhood Asperger Syndrome Test...
May 11, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28491125/indirect-maternal-deaths-uk-and-global-perspectives
#17
Manisha Nair, Catherine Nelson-Piercy, Marian Knight
Indirect maternal deaths outnumber direct deaths due to obstetric causes in many high-income countries, and there has been a significant increase in the proportion of maternal deaths due to indirect medical causes in low- to middle-income countries. This review presents a detailed analysis of indirect maternal deaths in the UK and a perspective on the causes and trends in indirect maternal deaths and issues related to care in low- to middle-income countries. There has been no significant decrease in the rate of indirect maternal deaths in the UK since 2003...
March 2017: Obstetric Medicine
https://www.readbyqxmd.com/read/28485834/profile-and-outcomes-of-women-with-pregnancy-related-acute-kidney-injury-requiring-dialysis-at-a-center-in-ethiopia
#18
Delayehu Bekele, Momina Ahmed, Ahmed Ibrahim, Seman Kedir, Grace Chan
OBJECTIVE: To describe the clinical profile and outcomes of women with pregnancy-related acute kidney injury (AKI) undergoing dialysis at Saint Paul's Hospital Millennium Medical College, Addis Ababa, where the first publicly funded large-scale dialysis service in Ethiopia was established. METHODS: In a hospital-based retrospective study, clinical records were reviewed for all women with pregnancy-related AKI attending the hemodialysis unit at the study center between August 2013 and July 2015...
May 9, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28485733/maternal-immune-activation-results-in-complex-microglial-transcriptome-signature-in-the-adult-offspring-that-is-reversed-by-minocycline-treatment
#19
D Mattei, A Ivanov, C Ferrai, P Jordan, D Guneykaya, A Buonfiglioli, W Schaafsma, P Przanowski, W Deuther-Conrad, P Brust, S Hesse, M Patt, O Sabri, T L Ross, B J L Eggen, E W G M Boddeke, B Kaminska, D Beule, A Pombo, H Kettenmann, S A Wolf
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of developing psychiatric pathologies in later life. This link may be bridged by a defective microglial phenotype in the offspring induced by MIA, as microglia have key roles in the development and maintenance of neuronal signaling in the central nervous system. The beneficial effects of the immunomodulatory treatment with minocycline on schizophrenic patients are consistent with this hypothesis. Using the MIA mouse model, we found an altered microglial transcriptome and phagocytic function in the adult offspring accompanied by behavioral abnormalities...
May 9, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28480843/prognostic-risk-of-obstetric-and-perinatal-complications-in-pregnant-women-with-thyroid-dysfunction
#20
N Morchiladze, B Tkeshelashvili, T Gagua, D Gagua
Maternal thyroid pathology takes important role in obstetric and peri-neonatal morbidity structure. Despite of the number of studies conducted in the field of thyroid disorders of pregnant females, the definition of influence of thyroid gland dysfunction on maternal and neonatal health still remains actual. The mentioned topics draw specific interest in the aspect of prognosticaiton of complications and unfavorable outcome. Aim of the study - to define the specificities of gestation period and determine the prognostic risk of obstetric and perinatal complications in pregnant females with thyroid pathology...
March 2017: Georgian Medical News
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