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Ida Steen, Sandra S Waehrens, Mikael A Petersen, Morten Münchow, Wender L P Bredie
The present study aimed to investigate coffee flavour perception and release as function of serving temperature to support standardisation in the specialty coffee branch. The coffee cultivar Bourbon Caturra was evaluated at six serving temperatures ranging from 31°C to 62°C. Coffee samples were analysed by dynamic headspace sampling gas chromatography-mass spectrometry and descriptive analyses using sip-and-spit tasting. The release of volatiles followed mostly the van't Hoff principle and was exuberated at temperatures above 40°C...
March 15, 2017: Food Chemistry
M Stavel, J Wong, Z Cieslak, R Sherlock, M Claveau, P S Shah
OBJECTIVE: To determine the effect of concomitant administration of prophylactic indomethacin and early enteral feeds on the risk of spontaneous intestinal perforation (SIP) in extremely low-birth-weight (ELBW) infants, and to describe the variation in prophylactic indomethacin use in Canada. STUDY DESIGN: A retrospective cohort study of 4268 ELBW infants born at <30 weeks' gestation admitted to Canadian neonatal units between 2010 and 2014 was conducted. Prophylactic indomethacin (I+ or I-, administered within 24 h) and early feeding (E+ or E-, initiated in the first 2 days) exposures were studied concurrently and independently...
October 20, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Ji-Yong An, Zhu-Hong You, Xing Chen, De-Shuang Huang, Guiying Yan, Da-Fu Wang
Self-interacting proteins (SIPs) play an essential role in cellular functions and the evolution of protein interaction networks (PINs). Due to the limitations of experimental self-interaction proteins detection technology, it is a very important task to develop a robust and accurate computational approach for SIPs prediction. In this study, we propose a novel computational method for predicting SIPs from protein amino acids sequence. Firstly, a novel feature representation scheme based on Local Binary Pattern (LBP) is developed, in which the evolutionary information, in the form of multiple sequence alignments, is taken into account...
October 19, 2016: Molecular BioSystems
Thomas B Brunner, Ursula Nestle, Sonja Adebahr, Eleni Gkika, Rolf Wiehle, Dimos Baltas, Anca-Ligia Grosu
OBJECTIVE: Stereotactic radiotherapy near serial organs at risk (OAR) requires special caution. A novel intensity-modulated radiotherapy (IMRT) prescription concept termed simultaneous integrated protection (SIP) for quantifiable and comparable dose prescription to targets very close to OAR is described. MATERIALS AND METHODS: An intersection volume of a planning risk volume (PRV) with the total planning target volume (PTV) defined the protection volume (PTVSIP)...
October 18, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Birju A Shah, Alison Migliori, Itsuka Kurihara, Surendra Sharma, Yow-Pin Lim, James Padbury
OBJECTIVE: To examine circulating levels of inter-alpha inhibitor protein (IaIp) in infants with necrotizing enterocolitis (NEC), spontaneous intestinal perforation (SIP), and matched controls to assess the diagnostic accuracy of IaIp to differentiate NEC from SIP and to compare receiver operating characteristics of IaIp for NEC with C-reactive protein (CRP). STUDY DESIGN: A prospective, nested case-control study of infants with feeding intolerance was carried out...
October 10, 2016: Journal of Pediatrics
Ji-Yong An, Zhu-Hong You, Xing Chen, De-Shuang Huang, Zheng-Wei Li, Gang Liu, Yin Wang
Self-interacting Proteins (SIPs) play an essential role in a wide range of biological processes, such as gene expression regulation, signal transduction, enzyme activation and immune response. Because of the limitations for experimental self-interaction proteins identification, developing an effective computational method based on protein sequence to detect SIPs is much important. In the study, we proposed a novel computational approach called RVMBIGP that combines the Relevance Vector Machine (RVM) model and Bi-gram probability (BIGP) to predict SIPs based on protein sequence...
October 8, 2016: Oncotarget
Yuki Kawata, Takahiro Yamamoto, Hideyuki Kihara, Yasuhisa Yamamura, Kazuya Saito, Kohji Ohno
Colloidal composites consisting of polymer-brush-afforded silica particles (P-SiPs) and a nematic liquid crystal (LC) exhibited three gel states with distinct viscoelastic and/or optical properties depending on temperature: (1) opaque hard gel, (2) translucent hard gel, and (3) translucent soft gel. We demonstrated that the transitions of the optical property and the hardness of the gels were due to the phase transition of the LC matrix and the glass transition of the grafted polymers of P-SiPs, respectively...
October 11, 2016: ACS Applied Materials & Interfaces
Atousa Abdollahi, Anita Eng, Liisa M Jantunen, Lutz Ahrens, Mahiba Shoeib, J Mark Parnis, Tom Harner
This study aimed to characterize the uptake of organophosphate esters (OPEs) by polyurethane foam (PUF) and sorbent-impregnated polyurethane foam (SIP) disk passive air samplers (PAS). Atmospheric OPE concentrations were monitored with high-volume active air samplers (HV-AAS) that were co-deployed with passive air samplers. Samples were analyzed for tris(2-chloroisopropyl) phosphate (TCIPP), tri(phenyl) phosphate (TPhP), tris(2-chloroethyl) phosphate (TCEP), and tris(2,3-dichloropropyl) phosphate (TDCIPP). The mean concentration of ∑OPEs in air was 2650 pg/m(3) for the HV-AAS...
October 7, 2016: Chemosphere
Kai Oliver Jensen, Leonhard Held, Andrea Kraus, Frank Hildebrand, Philipp Mommsen, Ladislav Mica, Guido A Wanner, Peter Steiger, Rudolf M Moos, Hans-Peter Simmen, Kai Sprengel
BACKGROUND: Although under discussion, induced hypothermia (IH) is an established therapy for patients with cardiac arrest or traumatic brain injuries. The influences on coagulopathy and bleeding tendency in severely injured patients (SIP) with concomitant traumatic brain injury are most widely unclear. Therefore, the aim of this study was to quantify the effect of mild IH in SIP with concomitant severe traumatic brain injuries on transfusion rate and mortality. METHODS: In this retrospective multi-centre study, SIP from three European level-1 trauma centres with an ISS ≥16 between 2009 and 2011 were included...
October 6, 2016: European Journal of Medical Research
Cang Zhao, Yu Qiao
The scanning electron microscope (SEM) has revealed a colorful three-dimensional world due to its great depth of field. However, the abundance of structural information imposes tough challenges to quantitative image analysis. In the current investigation, we developed a SEM-image polishing (SIP) based quantitative SEM-image analysis (QSIA) technique. As an example, QSIA was employed to characterize nanoporous silica. The results confirmed that the nanoporous silica samples, processed via sol-gel methods, were single-parameter, with the pore size being the only variable...
October 14, 2016: Nanoscale
Karen Müller Ramalho, Lárissa Marcondes Paladini de Souza, Isabel Peixoto Tortamano, Carlos Alberto Adde, Rodney Garcia Rocha, Carlos de Paula Eduardo
This randomized placebo-blind study aimed to evaluate the effect of laser phototherapy (LPT) on pain caused by symptomatic irreversible pulpitis (SIP). Sixty patients diagnosed with SIP were randomly assigned to treatment groups (n = 15): G1 (control), G2 (laser placebo-sham irradiation), G3 (laser irradiation at 780 nm, 40 mW, 4 J/cm(2)), and G4 (laser irradiation at 780 nm, 40 mW, 40 J/cm(2)). Spontaneous pain was recorded using a VAS score before (T0), immediately after (T1), and 15 min after treatment (T2)...
October 1, 2016: Lasers in Medical Science
Ngor Side Diagne, Massaman Camara, Abou Sy, Ousmane Cissé, Amadou Koura Ndao, Amadou Gallo Diop, Mouhamadou Mansour Ndiaye
OBJECTIVE: Therefore, the aim of our study was to determine risk factors for poor quality of life by considering disability after stroke in its multidimensional aspects but also to see the impact of each risk factor on the dimensions of quality of life. MATERIAL/PATIENTS AND METHODS: A prospective study of stroke patients confirmed, followed by neurovascular consultation at Fann Hospital in Dakar has been achieved. Quality of life was evaluated by the 65 Sikness Impact Profile (SIP 65), the depression by the scale of Beck...
September 2016: Annals of Physical and Rehabilitation Medicine
Philippine Dassonville, Stuart Nash, Valérie Servajean, Monique Sanchez, Stéphanie Mazza, Pascale Colliot, Sophie Jacquin-Courtois, Evelyne Klinger, Anne-Marie Schott, Laure Huchon, Laura Mechtouff, Laurent Derex, Norbert Nighoghossian, Tae-Hee Cho, Gilles Rode
OBJECTIVE: Describe cognitive impairments and their impact on activities of daily living after a minor stroke in the context of a "pilote" consultation done in hospices civils de Lyon between vascular neurology and physical and rehabilitation services. MATERIAL/PATIENTS AND METHODS: Thirty patients (21-67 years old) who have cognitive difficulties 6 months after minor stroke were included in the study. All patients received an assessment of complaints and cognitive performances (Montreal cognitive assessment scale, verbal span, 16 items free and cued recall, doors test, rey figure, symbol digit modalities test, verbal fluences, trail making test and the virtual action planning-supermarket test)...
September 2016: Annals of Physical and Rehabilitation Medicine
Etienne Savard
OBJECTIVE: Dysimmune encephalitis are neurologic diseases that are more and more diagnosed. Most of patients are young and active. Cognitive and behavior troubles can delay the diagnosis and can cause disability. Functional outcome is not routinely assessed. The aim of this study is to describe the activities and participation several months after the onset. MATERIALS/PATIENTS AND METHODS: Four cases have been handled in the same multidisciplinary rehabilitation unit...
September 2016: Annals of Physical and Rehabilitation Medicine
Amandine Chenet, Alexandra Gosseaume, Sandrine Wiertlewski, Brigitte Perrouin-Verbe
OBJECTIVE: Cognitive impairment in multiple sclerosis (MS) is common, present in 40 to 60% of patients, and is under diagnosis. Currently, there is no effective drug and non-pharmacological treatments that are developed. We propose to evaluate the effectiveness of exercise training (ET) on cognitive impairment. MATERIALS/PATIENTS AND METHODS: The study included patients from University Hospital of Nantes with an EDSS of between 3 and 4.5. They followed an exercise therapy program during 8 weeks, in groups, including aerobic physical activity (Nordic walking, gymnastics and exercise of balance) and recreational activities (billiards and boccia)...
September 2016: Annals of Physical and Rehabilitation Medicine
T Brunner, U Nestle, S Adebahr, E Gkika, R Wiehle, A Grosu
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Mara V Galmarini, Anne-Laure Loiseau, Michel Visalli, Pascal Schlich
Though the gastronomic sector recommends certain wine-cheese associations, there is little sensory evidence on how cheese influences the perception of wine. It was the aim of this study to dynamically characterize 4 wines as they would be perceived when consumed with and without cheese. The tasting protocol was based on multi-intake temporal dominance of sensations (TDS) coupled with hedonic rating. In the 1st session, 31 French wine and cheese consumers evaluated the wines (Pacherenc, Sancerre, Bourgogne, and Madiran) over 3 consecutive sips...
October 2016: Journal of Food Science
Lenette L Lu, Amy W Chung, Tracy R Rosebrock, Musie Ghebremichael, Wen Han Yu, Patricia S Grace, Matthew K Schoen, Fikadu Tafesse, Constance Martin, Vivian Leung, Alison E Mahan, Magdalena Sips, Manu P Kumar, Jacquelynne Tedesco, Hannah Robinson, Elizabeth Tkachenko, Monia Draghi, Katherine J Freedberg, Hendrik Streeck, Todd J Suscovich, Douglas A Lauffenburger, Blanca I Restrepo, Cheryl Day, Sarah M Fortune, Galit Alter
While a third of the world carries the burden of tuberculosis, disease control has been hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective vaccine. In many infectious diseases, antibodies (Abs) are powerful biomarkers and important immune mediators. However, in Mycobacterium tuberculosis (Mtb) infection, a discriminatory or protective role for humoral immunity remains unclear. Using an unbiased antibody profiling approach, we show that individuals with latent tuberculosis infection (Ltb) and active tuberculosis disease (Atb) have distinct Mtb-specific humoral responses, such that Ltb infection is associated with unique Ab Fc functional profiles, selective binding to FcγRIII, and distinct Ab glycosylation patterns...
October 6, 2016: Cell
Seth A Cohen, Zaid Chaudhry, Janine L Oliver, Evgeniy I Kreydin, My-Linh T Nguyen, Steven A Mills, A Lenore Ackerman, Ja-Hong Kim, Christopher M Tarnay, Shlomo Raz
INTRODUCTION AND OBJECTIVE: There is currently a national shortage of indigo carmine. In efforts to identify the most efficient aide for visualizing ureteral efflux intra-operatively, we wanted to investigate the time to excretion of phenazopyridine versus a newly identified alternative, sodium fluorescein. METHODS: We analyzed prospectively collected data from a cohort of women who underwent pelvic reconstructive surgery in 2015. Per provider preference patterns, a number of patients were administered 200 mg phenazopyridine orally with a sip of water, 1 hour prior to start of operative time...
September 21, 2016: Journal of Urology
Sonwabile Dzanibe, Peter V Adrian, Sheila Z Kimaro Mlacha, Shabir A Madhi
Group B Streptococcus (GBS) is a major cause of invasive disease in young infants and also in older immunocompromised individuals, including HIV-infected persons. We compared naturally acquired antibody titres to GBS polysaccharide and surface protein antigens in HIV-uninfected and HIV-infected children aged 4-7 years. A multiplex Luminex immunoassay was used to measure IgG concentrations against GBS capsular polysaccharides (CPS) for serotypes Ia, Ib, III and V; and also extracellular localizing proteins which included cell-wall anchored proteins: Fibrinogen binding surface Antigen (FbsA), GBS Immunogenic Bacterial Adhesin (BibA), Surface immunogenic protein (Sip), gbs0393, gbs1356, gbs1539, gbs0392; and lipoproteins gbs0233, gbs2106 and Foldase PsrA...
October 17, 2016: Vaccine
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