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https://www.readbyqxmd.com/read/29775017/-study-on-the-relationship-between-nasal-and-eye-symptoms-and-psychological-status-in-patients-with-allergic-rhinitis
#1
X He, Y Y Dong, Y Feng, B Q Wang
Objective: The aim of this study is to analysis the correlation between nasal and eye symptom and psychological status in patients with allergic rhinitis, in order to provide a basis for improving the mental health of patients. Method: The nasal symptom score scale, eye symptom score scale and Kessler 10 were used in the study, and the survey data was analyzed. Result: At least one of 147 patients had a nasal symptom at a rate of 100% (147/147); at least one ocular symptom was 86.4% (127/147). Of the 147 patients, 29 had K10 scores more than 21...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29774022/acute-zika-virus-infection-in-an-endemic-area-shows-modest-proinflammatory-systemic-immunoactivation-and-cytokine-symptom-associations
#2
Jéssica Barletto de Sousa Barros, Paulo Alex Neves da Silva, Rosemary de Carvalho Rocha Koga, Patrícia Gonzalez-Dias, José Rodrigues Carmo Filho, Patrícia Resende Alo Nagib, Verônica Coelho, Helder I Nakaya, Simone Gonçalves Fonseca, Irmtraut Araci Hoffmann Pfrimer
An early immune response to Zika virus (ZIKV) infection may determine its clinical manifestation and outcome, including neurological effects. However, low-grade and transient viremia limits the prompt diagnosis of acute ZIKV infection. We have investigated the plasma cytokine, chemokine, and growth factor profiles of 36 individuals from an endemic area displaying different symptoms such as exanthema, headache, myalgia, arthralgia, fever, hyperemia, swelling, itching, and nausea during early-phase infection...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29772618/-a-case-of-metastasis-of-cholangiocarcinoma-to-the-bladder
#3
Akiou Okumura, Akihiro Morii, Kiyoshi Takagawa, Hiroshi Kitamura
The patient was an 88-year-old male. He was referred to the Department of Internal Medicine because of total body itching and jaundice in July 2011. The serum bilirubin level was elevated, and the serum CA19-9 level was also elevated to 266. 6 U/ml. Computed tomography (CT) and endoscopic retrograde cholangiopancreatography (ERCP) revealed a solid tumor between the hepatic hilus and common bile duct, and choler cytodiagnosis was class V ; adenocarcinoma. The patient was diagnosed with hilar cholangiocarcinoma and received conservative treatment with endoscopic nasobiliary drainage (ENBD) due to his advanced age...
April 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29772565/safety-of-iohexol-administration-to-measure-glomerular-filtration-rate-in-different-patient-populations-a-25-year-experience
#4
Flavio Gaspari, Surabhi Thakar, Fabiola Carrara, Annalisa Perna, Matias Trillini, Maria Carolina Aparicio, Olimpia Diadei, Silvia Ferrari, Antonio Cannata, Nadia Stucchi, Piero Ruggenenti, Giuseppe Remuzzi, Norberto Perico
BACKGROUND/AIM: In clinical research setting, accurate and precise measurement of glomerular filtration rate (GFR) is essential to overcome the limitations of GFR estimation with equations, which are often unreliable. In recent decades, a method for measuring GFR by plasma clearance of iohexol, a non-ionic radiocontrast agent, was developed. To evaluate the safety of the procedure, we aimed to review all immediate adverse reactions that could be related to iohexol administration in our group's 25 years worth of experience...
May 17, 2018: Nephron
https://www.readbyqxmd.com/read/29771941/efficacy-of-ivermectin-mass-drug-administration-to-control-scabies-in-asylum-seekers-in-the-netherlands-a-retrospective-cohort-study-between-january-2014-march-2016
#5
Dorien T Beeres, Sofanne J Ravensbergen, Annelies Heidema, Darren Cornish, Machiel Vonk, Leonie D Wijnholds, Jessica J H Hendriks, Johanneke Kleinnijenhuis, Till F Omansen, Ymkje Stienstra
Scabies is a skin infestation with the mite Sarcoptes scabiei causing itch and rash and is a major risk factor for bacterial skin infections and severe complications. Here, we evaluated the treatment outcome of 2866 asylum seekers who received (preventive) scabies treatment before and during a scabies intervention programme (SIP) in the main reception centre in the Netherlands between January 2014 and March 2016. A SIP was introduced in the main national reception centre based on frequent observations of scabies and its complications amongst Eritrean and Ethiopian asylum seekers in the Netherlands...
May 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29767259/silencing-of-mir%C3%A2-155-suppresses-inflammatory-responses-in-psoriasis-through-inflammasome-nlrp3-regulation
#6
Quan Luo, Jingxin Zeng, Wei Li, Ling Lin, Xin Zhou, Xin Tian, Weiyu Liu, Lidan Zhang, Xibao Zhang
Psoriasis is a dermatosis with the major clinical symptoms of scale, erythema and itching, and it has a long disease course. In addition, it is easily recurrent and refractory, greatly affecting the physical and mental health of patients. In the present study, it was hypothesized that the function of miR‑155 increases psoriasis‑induced inflammation and that its expression may be dependent on inflammasome activation. miR‑155 expression was examined by gene chip array and quantitative polymerase chain reaction analysis...
May 14, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29765930/effect-of-fennel-on-the-health-status-of-menopausal-women-a-systematic-and-meta-analysis
#7
Talat Khadivzadeh, Mona Najaf Najafi, Leila Kargarfard, Masumeh Ghazanfarpour, Fatemeh Rajab Dizavandi, Imaneh Khorsand
Objectives: The aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females. Methods: A search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare , and menopause. Results: Fennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29762208/prevalence-of-atopic-dermatitis-and-pattern-of-drug-therapy-in-malaysian-children
#8
Yi-Yeong Goh, Fazlollah Keshavarzi, Yik Ling Chew
BACKGROUND: Atopic dermatitis (AD) is a chronic relapsing, noncontagious skin inflammation characterized by dry skin and itch. Mutation in filaggrin gene leads to defective skin barrier, allowing entry of allergen and eliciting immunological response. OBJECTIVES: The aims of this study were to investigate the prevalence of AD in Malaysian children and to understand the pattern of drug therapy. Such information could be useful to establish the relationship between ethnicity and family history of atopy and the development of associated signs and symptoms...
May 2018: Dermatitis
https://www.readbyqxmd.com/read/29760622/skin-and-mucous-membranes-manifestations-of-dermatological-diseases-within-the-genital-area-in-females
#9
Katarzyna Plagens-Rotman, Renata Przybylska, Zygmunt Adamski, Magdalena Czarnecka-Operacz
Introduction: Lichen sclerosus et atrophicus (LSA) and an inversed type of psoriasis belong to a group of benign dermatoses usually located within the region of female external genitalia. The most common subjective symptoms reported by patients are itching, pain and changes in the color and structure of the skin. Aim: This paper presents 3 cases of patients suffering from selected dermatoses located within the external female genitalia treated at the Department of Dermatology, Poznan University of Medical Sciences...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29760615/stress-itch-and-quality-of-life-in-chronic-urticaria-females
#10
Alicja Ograczyk-Piotrowska, Zofia Gerlicz-Kowalczuk, Anna Pietrzak, Anna M Zalewska-Janowska
Introduction: Chronic urticaria (CU) belongs to a group of psychodermatological disorders, thus stress can play a significant role in this dermatosis onset and/or exacerbation. On the other hand, the disease itself accompanied by itch, may be a source of distress and could worsen patients' quality of life (QoL). Aim: The first goal of our study was to compare stress intensity between CU subjects and the control group. The second aim was to investigate the relationships between disease-related parameters (CU severity, itch) and psychological variables (stress and QoL) in CU patients...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29760570/plasma-rich-in-growth-factors-eye-drops-to-treat-secondary-ocular-surface-disorders-in-patients-with-glaucoma
#11
Ronald M Sánchez-Avila, Jesus Merayo-Lloves, Maria Laura Fernández, Luis Alberto Rodríguez-Gutiérrez, Pedro Pablo Rodríguez-Calvo, Andres Fernández-Vega Cueto, Francisco Muruzabal, Gorka Orive, Eduardo Anitua
Purpose: To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) eye drops in patients with glaucoma with secondary ocular surface disorders (OSDs) due to surgeries and topical hypotensive drugs use. Materials and methods: A retrospective case-series study design was used including six patients (eight eyes) diagnosed with glaucoma who received surgical (nonpenetrating deep sclerectomy and/or trabeculectomy) and medical treatments (hypotensive eye drops) to control intraocular pressure (IOP) and who developed secondary OSDs, unresponsive to conventional treatments...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29757564/-re-operation-treatment-in-uremic-patients-complicated-with-persistent-secondary-hyperparathyroidism-after-parathyroidectomy-with-autotransplantation
#12
Shao Jun Bo, Xian Fa Xu, Chuan Ya Qiu, Tian Tian Wang, Yu Dong Ning, Hong Yue Li
Objective: To analyze the clinical profile and therapeutic effect of re-operation treatment in uremic patients complicated with persistent secondary hyperparathyroidism(SHPT)after parathyroidectomy with autotransplantation. Method: Twelve persistent SHPT patients who were treated with reoperation of paramyroidectomy(PTX)were enrolled in this study during the period from Jan 2014 to Jul 2017 in our hospital.We evaluated the location of the remaining parathyroid glands by ultrasonography,dual-phase 99 Tcm-sestamibi scintigraphy,CT and MR imaging of the neck before the operation...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29756157/influence-of-itch-and-pain-on-sleep-quality-in-patients-with-hidradenitis-suppurativa
#13
Karolina Kaaz, Jacek C Szepietowski, Łukasz Matusiak
There is a lack of data evaluating the influence of hidradenitis suppurativa-related subjective symptoms on sleep quality. The aim of this study was to assess the influence of itch and pain on sleep quality in 108 patients with hidradenitis suppurativa compared with 50 controls. The Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate a spectrum of sleep disturbances. Mean ± standard deviation AIS and PSQI scores among patients with hidradenitis suppurativa vs. controls were assessed as 5...
May 14, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29754528/canadian-patients-preferences-in-topical-psoriasis-care-insights-from-the-propel-surveys
#14
Ronald Vender, Melinda J Gooderham, Lyn C Guenther, Dimitrios Kyritsis, Jaggi Rao, Alice Kowalczyk, John Ashkenas
BACKGROUND: Patients with psoriasis of all severities employ topical treatment, either alone or in combination. Promoting Patient Engagement at the Leading Edge of Topical Psoriasis Treatment (PROPEL) surveyed Canadian dermatologists and their patients about their attitudes toward topical care. OBJECTIVES: To identify gaps between patients and dermatologists regarding the burden of psoriasis, the burden of treatment, and priorities for topical care to Canadian patients with psoriasis...
May 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29753452/exploring-the-acceptability-of-using-low-friction-bedding-for-patients-with-burns-qualitative-results-from-the-silkie-study
#15
K Whale, J C Ingram, S George, F Spickett-Jones, A Sack, A E Young
BACKGROUND: Skin grafts following deep burns are needed to ensure healing. Grafts that fail and require re-grafting cause significant distress to patients and additional costs for the NHS. Shearing, which leads to graft loss, may be reduced through the use of low-friction bedding. A feasibility study was conducted to assess proof of concept for the use of low-friction bedding for patients with burns. Patient, parent and staff views on the acceptability of this material were explored through semi-structured interviews...
May 9, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29752810/a-prospective-study-of-female-genital-chronic-graft-versus-host-disease-symptoms-signs-diagnosis-and-treatment
#16
Eva Smith Knutsson, Yvonne Björk, Anna-Karin Broman, Lotti Helström, Malin Nicklasson, Mats Brune, Karin Sundfeldt
INTRODUCTION: Female genital chronic graft-versus-host disease (cGvHD) is a complication of allogeneic hematopoietic cell transplantation (alloHCT) for blood malignancies. Unattended inflammation and fibrosis in the vulva and vagina may lead to total vaginal stenosis. The course and treatment of genital cGvHD was observed in this population-based prospective study. MATERIAL AND METHODS: Women (n = 41) receiving alloHCT in 2005-2010 were examined before and at 3, 6, 9, 12, 18, 24, 30, and 36 months post-transplant...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29750047/skin-acceptability-of-a-cosmetic-moisturizer-formulation-in-female-subjects-with-sensitive-skin
#17
Stephanie J Nisbet
Purpose: This 3-week, open-label, noncomparative clinical study evaluated the skin acceptability of a cosmetic moisturizer in subjects with sensitive skin, by monitoring adverse events (AEs) and cutaneous discomfort related to normal usage. Materials and methods: Female subjects aged between 18-60 years, with Fitzpatrick phototype classification I-IV and sensitive skin, verified by a positive reaction on the stinging test at screening, were included. Subjects applied the moisturizer to their face and body twice daily for 21±2 days at home and recorded study product usage and feelings of cutaneous discomfort (eg, dryness, prickling, stinging, and itching) in a diary; any AEs were reported to the clinic...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29747232/efficacy-and-safety-of-ixekizumab-in-a-randomized-double-blinded-placebo-controlled-phase-3b-study-of-patients-with-moderate-to-severe-genital-psoriasis
#18
C Ryan, A Menter, L Guenther, A Blauvelt, R Bissonnette, K Meeuwis, J Sullivan, J C Cather, G Yosipovitch, A B Gottlieb, J F Merola, K Callis Duffin, S Fretzin, O O Osuntokun, R Burge, A N Naegeli, F E Yang, C-Y Lin, K Todd, A Potts Bleakman
BACKGROUND: Genital psoriasis (GenPs) is a common, debilitating, and difficult to treat manifestation of plaque psoriasis. However, few controlled, interventional studies of GenPs exist. OBJECTIVE: To determine the efficacy of ixekizumab versus placebo in patients with moderate-to-severe GenPs with BSA≥1%. METHODS: Subjects with moderate-to-severe GenPs (defined as a baseline static Physician's Global Assessment of Genitalia [sPGA-G] score of ≥3) with BSA≥1% were randomized 1:1 to receive placebo (N=74) or the recommended dosing of ixekizumab (N=75)...
May 10, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29745452/efficacy-of-a-shower-cream-and-a-lotion-with-skin-identical-lipids-in-healthy-subjects-with-atopic-dry-skin
#19
Enzo Berardesca, Susan Mortillo, Norma Cameli, Marco Ardigo, Maria Mariano
BACKGROUND: Atopic dermatitis is a chronic, pruritic inflammatory skin disease that adversely affects quality of life. AIMS: The current study evaluates the efficacy of a shower cream and a lotion, each with skin-identical lipids and emollients, in the treatment of atopic dry skin of subjects with a history of atopic condition. METHODS: In all, 40 healthy females with clinically dry skin on the lower legs were enrolled in the study and underwent 4 weeks of daily use of the shower cream and 2 additional weeks of both the shower cream and the body lotion...
May 10, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29740719/properties-of-zinc-oxide-nanoparticles-and-their-activity-against-microbes
#20
REVIEW
Khwaja Salahuddin Siddiqi, Aziz Ur Rahman, Tajuddin, Azamal Husen
Zinc oxide is an essential ingredient of many enzymes, sun screens, and ointments for pain and itch relief. Its microcrystals are very efficient light absorbers in the UVA and UVB region of spectra due to wide bandgap. Impact of zinc oxide on biological functions depends on its morphology, particle size, exposure time, concentration, pH, and biocompatibility. They are more effective against microorganisms such as Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Sarcina lutea, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Pseudomonas vulgaris, Candida albicans, and Aspergillus niger...
May 8, 2018: Nanoscale Research Letters
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