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https://www.readbyqxmd.com/read/27922026/percutaneous-gastrostomy-device-for-the-treatment-of-class-ii-and-class-iii-obesity-results-of-a-randomized-controlled-trial
#1
Christopher C Thompson, Barham K Abu Dayyeh, Robert Kushner, Shelby Sullivan, Alan B Schorr, Anastassia Amaro, Caroline M Apovian, Terrence Fullum, Amir Zarrinpar, Michael D Jensen, Adam C Stein, Steven Edmundowicz, Michel Kahaleh, Marvin Ryou, J Matthew Bohning, Gregory Ginsberg, Christopher Huang, Daniel D Tran, Joseph P Glaser, John A Martin, David L Jaffe, Francis A Farraye, Samuel B Ho, Nitin Kumar, Donna Harakal, Meredith Young, Catherine E Thomas, Alpana P Shukla, Michele B Ryan, Miki Haas, Heidi Goldsmith, Jennifer McCrea, Louis J Aronne
OBJECTIVES: The AspireAssist System (AspireAssist) is an endoscopic weight loss device that is comprised of an endoscopically placed percutaneous gastrostomy tube and an external device to facilitate drainage of about 30% of the calories consumed in a meal, in conjunction with lifestyle (diet and exercise) counseling. METHODS: In this 52-week clinical trial, 207 participants with a body-mass index (BMI) of 35.0-55.0 kg/m(2) were randomly assigned in a 2:1 ratio to treatment with AspireAssist plus Lifestyle Counseling (n=137; mean BMI was 42...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27921217/don-t-make-me-angry-you-wouldn-t-like-me-when-i-m-angry-volitional-choices-to-act-or-inhibit-are-modulated-by-subliminal-perception-of-emotional-faces
#2
Jim Parkinson, Sarah Garfinkel, Hugo Critchley, Zoltan Dienes, Anil K Seth
Volitional action and self-control-feelings of acting according to one's own intentions and in being control of one's own actions-are fundamental aspects of human conscious experience. However, it is unknown whether high-level cognitive control mechanisms are affected by socially salient but nonconscious emotional cues. In this study, we manipulated free choice decisions to act or withhold an action by subliminally presenting emotional faces: In a novel version of the Go/NoGo paradigm, participants made speeded button-press responses to Go targets, withheld responses to NoGo targets, and made spontaneous, free choices to execute or withhold the response for Choice targets...
December 5, 2016: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/27921192/actual-10-year-survivors-after-resection-of-hepatocellular-carcinoma
#3
Jian Zheng, Deborah Kuk, Mithat Gönen, Vinod P Balachandran, T Peter Kingham, Peter J Allen, Michael I D'Angelica, William R Jarnagin, Ronald P DeMatteo
BACKGROUND: Resection of hepatocellular carcinoma (HCC) offers a chance of cure, but recurrence is common and survival is often limited. The clinical and pathological characteristics of long-term survivors have not been well studied. METHODS: We retrospectively reviewed 212 patients who underwent partial hepatectomy for HCC with curative intent from 1992 to 2006. Fifty patients who survived beyond 10 years were compared with 109 patients who died of recurrence within 10 years...
December 5, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27921166/outcome-in-unresectable-glioblastoma-mgmt-promoter-methylation-makes-the-difference
#4
Niklas Thon, Jun Thorsteinsdottir, Sabina Eigenbrod, Ulrich Schüller, Jürgen Lutz, Simone Kreth, Claus Belka, Jörg-Christian Tonn, Maximilian Niyazi, Friedrich Wilhelm Kreth
In 2011, we reported a predominant prognostic/predictive role of MGMT promoter methylation status on progression-free survival (PFS) in unresectable glioblastoma patients undergoing upfront radiotherapy plus concomitant and maintenance temozolomide (RTX/TMZ → TMZ). We, here, present the final results of this prospective study focussing on the prognostic/predictive value of MGMT promoter methylation status for death risk stratification. Overall, 56 adult patients with unresectable, biopsy proven glioblastoma were prospectively assigned to upfront RTX/TMZ → TMZ treatment between March 2006 and August 2008...
December 5, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27921123/local-control-and-intermediate-term-cosmetic-outcome-following-imrt-for-nasal-tumors-an-update
#5
Yuki Mukai, Stefan Janssen, Christoph Glanzmann, David Holzmann, Gabriela Studer
OBJECTIVE: This study aims to evaluate local control and intermediate-term cosmetic outcome in patients with cancer of the nose treated with intensity-modulated radiotherapy (IMRT). METHODS: From June 2008 to September 2015, 36 consecutive patients presenting with nasal cavity, ala of the nose, or nasal vestibule tumors were treated at the Department of Radiation Oncology, University Hospital Zurich either postoperatively (n = 14; 3/14 with nasal ablation) or with definitive IMRT (n = 22)...
December 5, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27921099/thermoresponsive-microgels-containing-trehalose-as-soft-matrices-for-3d-cell-culture
#6
Małgorzata Burek, Sylwia Waśkiewicz, Anna Lalik, Sebastian Student, Tadeusz Bieg, Ilona Wandzik
A series of thermoresponsive glycomicrogels with trehalose in the cross-links or with trehalose in the cross-links and as pending moieties was synthesized. These materials were obtained by surfactant-free precipitation copolymerization of N-isopropylacrylamide and various amounts of trehalose monomers. The resultant particles showed a spherical shape and a submicrometer hydrodynamic size with a narrow size distribution. At 25 °C, glycomicrogels in solutions with physiological ionic strength formed stable colloids, which further gelled upon heating to physiological temperature forming a macroscopic hydrogel with an interconnected porous structure...
December 6, 2016: Biomaterials Science
https://www.readbyqxmd.com/read/27921002/intention-for-cesarean-section-versus-vaginal-delivery-among-pregnant-women-in-isfahan-correlates-and-determinants
#7
Zahra Shams-Ghahfarokhi, Farideh Khalajabadi-Farahani
BACKGROUND: Iran has the second highest rate of cesarean section in the world. the corresponding rate in the third metropolitan city of Iran, Isfahan, is even higher. This paper aimed to assess correlates and determinants of intention for cesarean section versus normal vaginal delivery (NVD) among pregnant women in Isfahan. METHODS: A study was conducted among 400 pregnant women aged 18-38 years, with gestational age of 24-40 weeks who attended labor clinics of nine hospitals in Isfahan during June and July 2014...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27920978/network-interactions-underlying-mirror-feedback-in-stroke-a-dynamic-causal-modeling-study
#8
Soha Saleh, Mathew Yarossi, Thushini Manuweera, Sergei Adamovich, Eugene Tunik
Mirror visual feedback (MVF) is potentially a powerful tool to facilitate recovery of disordered movement and stimulate activation of under-active brain areas due to stroke. The neural mechanisms underlying MVF have therefore been a focus of recent inquiry. Although it is known that sensorimotor areas can be activated via mirror feedback, the network interactions driving this effect remain unknown. The aim of the current study was to fill this gap by using dynamic causal modeling to test the interactions between regions in the frontal and parietal lobes that may be important for modulating the activation of the ipsilesional motor cortex during mirror visual feedback of unaffected hand movement in stroke patients...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27920618/analysis-and-adjustment-of-vertebral-subluxation-as-a-separate-and-distinct-identity-for-the-chiropractic-profession-a-commentary
#9
REVIEW
John Hart
OBJECTIVE: The purpose of this paper is to discuss various statements related to chiropractic identity from(1) D. D. Palmer(2); selected chiropractic organizations, associations, and colleges; and(3) attitudes and perceptions of chiropractic from chiropractic students, practitioners, and patients. DISCUSSION: For comparison purposes, identity statements and perceptions from the various chiropractic associations and colleges, as well as from students and patients, were explored...
December 2016: Journal of Chiropractic Humanities
https://www.readbyqxmd.com/read/27920615/spinal-health-the-backbone-of-chiropractic-s-identity
#10
Richard A Brown
OBJECTIVES: The purpose of this commentary is to explore the concepts underpinning professional identity, assess their relevance to chiropractic, and propose a model by which a strong identity for the chiropractic profession may be achieved. DISCUSSION: The professional identity of chiropractic has been a constant source of controversy throughout its history. Attempts to establish a professional identity have been met with resistance from internal factions divided over linguistics, philosophy, technique, and chiropractic's place in the health care framework...
December 2016: Journal of Chiropractic Humanities
https://www.readbyqxmd.com/read/27920416/re-evaluating-the-inhibition-of-stress-erosions-revise-a-protocol-for-pilot-randomized-controlled-trial
#11
Waleed Alhazzani, Gordon Guyatt, John C Marshall, Richard Hall, John Muscedere, Francois Lauzier, Lehana Thabane, Mohammed Alshahrani, Shane W English, Yaseen M Arabi, Adam M Deane, Tim Karachi, Bram Rochwerg, Simon Finfer, Nick Daneman, Nicole Zytaruk, Diane Heel-Ansdell, Deborah Cook, On Behalf Of
INTRODUCTION: Clinicians routinely administer stress ulcer prophylaxis to mechanically ventilated patients in the intensive care unit (ICU), most commonly prescribing proton pump inhibitors (PPIs). However, the incidence of gastrointestinal (GI) bleeding from stress ulceration is low and recent observational studies suggest these agents may increase infections. Therefore, a large randomized clinical trial (RCT) is needed to inform modern practice. The aim of this multicenter pilot trial is to determine the feasibility of performing a large RCT to investigate the efficacy and safety of withholding intravenous pantoprazole...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27920357/use-of-a-bogus-pipeline-to-detect-men-s-underreporting-of-sexually-aggressive-behavior
#12
Emily Strang, Zoë D Peterson
Researchers rely on men's self-reports of sexually aggressive behavior to identify the prevalence and correlates of men's perpetration (i.e., their use of verbal or physical coercion to obtain sex from a nonconsenting partner). However, results from research based on men's self-reported sexual perpetration are suspect because men may intentionally conceal their sexually aggressive behavior. The current study used a Bogus Pipeline (BPL) methodology to determine whether young, community men (N = 93) intentionally underreport their use of sexually aggressive strategies on two self-report measures of perpetration...
December 4, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/27919972/clinical-burden-of-c-reactive-protein-albumin-ratio-before-curative-surgery-for-patients-with-gastric-cancer
#13
Yuji Toiyama, Tadanobu Shimura, Hiromi Yasuda, Hiroyuki Fujikawa, Yoshiki Okita, Minako Kobayashi, Masaki Ohi, Shigeyuki Yoshiyama, Jyunichiro Hiro, Toshimitsu Araki, Yasuhiro Inoue, Yasuhiko Mohri, Masato Kusunoki
To assess the relationship of C-reactive protein/albumin ratio (CAR) to outcomes and surgical site infection (SSI) in gastric cancer (GC) treated with curative intent, we retrospectively assessed 384 patients with GC for CAR, SSIs, disease-free survival (DFS), overall survival (OS) and other factors. We found SSIs in 42 patients (10.9%). Pathological T-stage, TNM classification, body mass index, duration of surgery, blood loss and preoperative CAR were significantly associated with SSIs; in multivariate analyses, CAR [hazard ratio (HR)=2...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919941/ectopic-myoglobin-expression-is-associated-with-a-favourable-outcome-in-head-and-neck-squamous-cell-carcinoma-patients
#14
Sebastian Meller, Anne VAN Ellen, Heidrun Gevensleben, Anne Bicker, Thomas Hankeln, Thomas A Gorr, Verena Sailer, Freya Dröge, Friederike Schröck, Friedrich Bootz, Andreas Schröck, Sven Perner, Dimo Dietrich, Glen Kristiansen
BACKGROUND/AIM: Ectopic myoglobin (MB) expression, mediated by alternative and hypoxia-inducible transcription, has recently been demonstrated in several epithelial tumours. This study aimed to examine the expression of MB in hormone-independent head and neck squamous cell carcinomas (HNSCCs). PATIENTS AND METHODS: Using imunohistochemistry, ectopic MB expression was analyzed on tissue microarrays (TMAs) of 524 patients with localized and locally advanced primary and recurrent HNSCC who had undergone surgical treatment with curative intent...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919404/individualized-metacognitive-therapy-for-delusions-a-randomized-controlled-rater-blind-study
#15
Christina Andreou, Charlotte E Wittekind, Martina Fieker, Ulrike Heitz, Ruth Veckenstedt, Francesca Bohn, Steffen Moritz
BACKGROUND: Theory-driven interventions targeting specific factors that contribute to delusions are receiving increased interest. The present study aimed to assess the efficacy of individualized metacognitive therapy (MCT+), a short manualized intervention that addresses delusion-associated cognitive biases. METHODS: 92 patients with current or past delusions were randomized to receive 12 twice-weekly sessions of either MCT+ or a control intervention within a randomized controlled rater-blind design...
November 29, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27919400/a-novel-concept-for-integrating-and-delivering-health-information-using-a-comprehensive-digital-dashboard-an-analysis-of-healthcare-professionals-intention-to-adopt-a-new-system-and-the-trend-of-its-real-usage
#16
Keehyuck Lee, Se Young Jung, Hee Hwang, Sooyoung Yoo, Hyun Young Baek, Rong-Min Baek, Seok Kim
OBJECTIVE: To introduce a new concept of medical dashboard system called BESTBoard. Such a system was implemented in all wards in a tertiary academic hospital to explore the development process, core designs, functions, usability and feasibility. METHODS: The task-force team made user interface designs for 6 months based on a need analysis. Hardware configuration and software development was carried out for 3 months. We conducted a survey of 383 physicians and nurses to determine the usability and feasibility of the system...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27919381/consumer-choice-of-on-demand-mhealth-app-services-context-and-contents-values-using-structural-equation-modeling
#17
Euehun Lee, Semi Han, Sang Hyun Jo
OBJECTIVE: As smartphone penetration increases and the technology advances, various mobile services have reached the market. mHealth Applications are specifically highlighted for phenomena such as global aging & well-being, but the technology-driven mHealth services have not been successful in the market because consumer needs have not been reflected in the services properly. This study developed a research model consisting of context/contents values to explain the intention of consumers over the age of 40 in using mHealth Applications...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27919261/caf%C3%A3-a-multicomponent-audit-and-feedback-intervention-to-improve-implementation-of-healthy-food-policy-in-primary-school-canteens-a-randomised-controlled-trial
#18
Sze Lin Yoong, Nicole Nathan, Luke Wolfenden, John Wiggers, Kathryn Reilly, Christopher Oldmeadow, Rebecca Wyse, Rachel Sutherland, Tessa Delaney, Peter Butler, Lisa Janssen, Sarah Preece, Christopher M Williams
BACKGROUND: The implementation of nutrition policies in schools has been recommended as a strategy to improve child dietary intake. Internationally, research suggests that the majority of schools do not implement these policies. In New South Wales (NSW), Australia, the NSW Healthy School Canteen Policy requires that school canteens prohibit the sale of 'red' foods (i.e. foods that are typically nutrient poor and high in energy, such as confectionary and deep-fried foods) and 'banned'drinks (i...
December 5, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27919239/psychosocial-determinants-of-parental-human-papillomavirus-hpv-vaccine-decision-making-for-sons-methodological-challenges-and-initial-results-of-a-pan-canadian-longitudinal-study
#19
Samara Perez, Ovidiu Tatar, Gilla K Shapiro, Eve Dubé, Gina Ogilvie, Juliet Guichon, Vladimir Gilca, Zeev Rosberger
BACKGROUND: HPV vaccination decision-making is a complex process that is influenced by multiple psychosocial determinants. Given the change in policy recommendation to include males in routine HPV vaccination, our goals were to assess the HPV vaccination uptake in Canada, to understand where Canadian parents were situated in the HPV vaccine decision-making process for their son, how they changed over time and which psychosocial determinants were relevant for this process. METHODS: We used an online survey methodology and collected data from a nationally representative sample of Canadian parents of boys aged 9-16 at baseline (T1, February 2014) and at 9 months' follow-up (T2)...
December 5, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27919206/differences-and-similarities-in-therapeutic-mode-use-between-occupational-therapists-and-occupational-therapy-students-in-norway
#20
Tove Carstensen, Tore Bonsaksen
BACKGROUND: The Intentional Relationship Model (IRM) is a new model of the therapeutic relationship in occupational therapy practice. Two previous studies have focused on therapist communication style, or 'mode' use, but to date no group comparisons have been reported. AIM: To explore differences between occupational therapists and occupational therapy students with regard to their therapeutic mode use. METHODS: The study had a cross-sectional design, and convenience samples consisting of occupational therapists (n = 109) and of second-year occupational therapy students (n = 96) were recruited...
December 5, 2016: Scandinavian Journal of Occupational Therapy
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