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https://www.readbyqxmd.com/read/29791435/immunogenicity-and-efficacy-following-sequential-parenterally-administered-doses-of-salmonella-enteritidis-cops-flic-glycoconjugates-in-infant-and-adult-mice
#1
Scott M Baliban, Brittany Curtis, Deanna Toema, Sharon M Tennant, Myron M Levine, Marcela F Pasetti, Raphael Simon
In sub-Saharan Africa, invasive nontyphoidal Salmonella (iNTS) infections with serovars S. Enteritidis, S. Typhimurium and I 4,[5],12:i:- are widespread in children < 5 years old. Development of an efficacious vaccine would provide an important public health tool to prevent iNTS disease in this population. Glycoconjugates of S. Enteritidis core and O-polysaccharide (COPS) coupled to the homologous serovar phase 1 flagellin protein (FliC) were previously shown to be immunogenic and protected adult mice against death following challenge with a virulent Malian S...
May 23, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29791278/specificity-of-postural-control-comparing-expert-and-intermediate-dancers
#2
Jörn Munzert, Jelena Müller, Michael Joch, Mathias Reiser
The expert-novice approach is inappropriate for studying postural control in sport and dance when novices are completely unable to perform relevant postural tasks and experts cannot demonstrate specific skills on everyday postural tasks. We tested expertise-specific differences on 6 static everyday and 5 dynamic dance-like postural tasks of varying difficulty in 13 professional and 12 intermediate nonprofessional dancers. Results showed a clear expert advantage on sway area for dance-like postural tasks, but not for static everyday tasks...
May 23, 2018: Journal of Motor Behavior
https://www.readbyqxmd.com/read/29786465/trunk-stability-enabled-by-non-invasive-spinal-electrical-stimulation-after-spinal-cord-injury
#3
Mrinal Rath, Albert H Vette, Shyamsundar Ramasubramaniam, Kun Li, Joel Burdick, Victor Reggie Edgerton, Yury Gerasimenko, Dimitry Sayenko
Electrical neuromodulation of spinal networks improves the control of movement of the paralyzed limbs after spinal cord injury (SCI). However, the potential of non-invasive spinal stimulation to facilitate postural trunk control during sitting in humans with SCI has not been investigated. We hypothesized that transcutaneous electrical stimulation of the lumbosacral enlargement can improve trunk posture. Eight participants with non-progressive SCI, C3-T9, AIS A or C, performed different motor tasks during sitting...
May 22, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29785097/inter-gender-differences-of-balance-indicators-in-persons-60-90-years-of-age
#4
Ewa Puszczalowska-Lizis, Przemyslaw Bujas, Slawomir Jandzis, Jaroslaw Omorczyk, Marek Zak
Introduction: Precision of movements responsible for maintaining balance deteriorates with age due to natural involutionary processes, thus prompting a research question whether the values of gender-related stability indicators might differ significantly among the study subjects over 60 years of age. Methods: The study group comprised 136 seniors (89 women, 47 men; aged 60-90 years). The CQ-Stab 2P 2-platform posturograph was used as the main research device, whereas the Mann-Whitney U -test was used to evaluate the gender-related differences in the average level of variables...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29782218/postural-control-and-physiological-responses-to-a-simulated-match-in-u-20-judo-competitors
#5
Luis Santos, Javier Fernández-Río, Eliseo Iglesias-Soler, Miguel Blanco-Traba, Markus Due Jakobsen, Vicente González-Díez, Emerson Franchini, Carlos Gutiérrez, Xurxo Dopico-Calvo, Eduardo Carballeira-Fernández, William Amonette, Oscar Suman
The aim was to evaluate the effects of judo combat on the athletes' postural control (PC) and physiological loading before, during and after a simulated match. Seventeen under-20 regional and national level athletes completed one modified 7-min match. At baseline, during the combat (3rd and 7th minutes) and 2-min post-match centre of pressure (CoP) parameters were assessed. Heart rate (HR), blood lactate (BLa) and rating of perceived exertion (RPE) and local RPE (LRPE) were collected. Significant increments were observed in CoP mean positioning and velocity at 3rd and 7th minutes, but the CoP deviation in both axes was unaffected...
May 21, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29780476/trends-in-activity-for-the-oxygen-evolution-reaction-on-transition-metal-m-fe-co-ni-phosphide-pre-catalysts
#6
Junyuan Xu, Junjie Li, Dehua Xiong, Bingsen Zhang, Yuefeng Liu, Kuang-Hsu Wu, Isilda Amorim, Wei Li, Lifeng Liu
Transition metal phosphides (TMPs) have recently emerged as a new class of pre-catalysts that can efficiently catalyze the oxygen evolution reaction (OER). However, how the OER activity of TMPs varies with the catalyst composition has not been systematically explored. Here, we report the alkaline OER electrolysis of a series of nanoparticulate phosphides containing different equimolar metal (M = Fe, Co, Ni) components. Notable trends in OER activity are observed, following the order of FeP < NiP < CoP < FeNiP < FeCoP < CoNiP < FeCoNiP, which indicate that the introduction of a secondary metal(s) to a mono-metallic TMP substantially boosts the OER performance...
April 14, 2018: Chemical Science
https://www.readbyqxmd.com/read/29774606/nitrogen-doped-cop-electrocatalysts-for-coupled-hydrogen-evolution-and-sulfur-generation-with-low-energy-consumption
#7
Qingwen Zhou, Zihan Shen, Chao Zhu, Jiachen Li, Zhiyuan Ding, Peng Wang, Feng Pan, Zhiyong Zhang, Haixia Ma, Shuangyin Wang, Huigang Zhang
Hydrogen production is the key step for the future hydrogen economy. As a promising H2 production route, electrolysis of water suffers from high overpotentials and high energy consumption. This study proposes an N-doped CoP as the novel and effective electrocatalyst for hydrogen evolution reaction (HER) and constructs a coupled system for simultaneous hydrogen and sulfur production. Nitrogen doping lowers the d-band of CoP and weakens the H adsorption on the surface of CoP because of the strong electronegativity of nitrogen as compared to phosphorus...
May 17, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29772030/correction-gestational-dietary-protein-is-associated-with-sex-specific-decrease-in-blood-flow-fetal-heart-growth-and-post-natal-blood-pressure-of-progeny
#8
Juan H Hernandez-Medrano, Katrina J Copping, Andrew Hoare, Wendela Wapanaar, Rosalie Grivell, Tim Kuchel, Giuliana Miguel-Pacheco, I Caroline McMillen, Raymond J Rodgers, Viv E A Perry
[This corrects the article DOI: 10.1371/journal.pone.0125694.].
2018: PloS One
https://www.readbyqxmd.com/read/29770907/sit-still-and-pay-attention-using-the-wii-balance-board-to-detect-lapses-in-concentration-in-children-during-psychophysical-testing
#9
Pete R Jones
During psychophysical testing, a loss of concentration can cause observers to answer incorrectly, even when the stimulus is clearly perceptible. Such lapses limit the accuracy and speed of many psychophysical measurements. This study evaluates an automated technique for detecting lapses based on body movement (postural instability). Thirty-five children (8-11 years of age) and 34 adults performed a typical psychophysical task (orientation discrimination) while seated on a Wii Fit Balance Board: a gaming device that measures center of pressure (CoP)...
May 16, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29763813/age-and-gymnastic-experience-effects-on-sensory-reweighting-processes-during-quiet-stand
#10
Albert Busquets, Silvia Aranda-Garcia, Blai Ferrer-Uris, Michel Marina, Rosa Angulo-Barroso
BACKGROUND: The relative contribution of sensory inputs to control balance while standing is dynamically adjusted. These sensory reweighting processes could be impacted by age and sport expertise capabilities, especially when the sport emphasizes equilibrium like artistic gymnastics. RESEARCH QUESTION: The aim of this study was to explore the sensory reweighting processes to adjust standing posture in children and adults with different gymnastic expertise (gymnasts, G, and non-gymnast, NG)...
May 8, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29762620/m-x-p-m-co-ni-carbon-core-shell-nanoparticles-embedded-in-3d-cross-linked-graphene-aerogel-derived-from-seaweed-biomass-for-hydrogen-evolution-reaction
#11
Wentong Zhao, Xiaoqing Lu, Manickam Selvaraj, Wei Wei, Zhifeng Jiang, Nabi Ullah, Jie Liu, Jimin Xie
Low-cost electrocatalysts play an important role in the hydrogen evolution reaction (HER). Particularly, transition metal phosphides (TMPs) are widely applied in the development of HER electrocatalysts. To improve the poor electrochemical reaction kinetics of HER, we introduce a facile way to synthesize carbon core-shell materials containing cobalt phosphide nanoparticles embedded in different graphene aerogels (GAs) (CoP@C-NPs/GA-x (x = 5, 10 and 20)) using seaweed biomass as precursors. The synthesized CoP@C-NPs/GA-5 exhibits efficient catalytic activity with small overpotentials of 120 and 225 mV at current densities of 10 mA cm-2, along with the low Tafel slopes of 57 and 66 mV dec-1, for HER in acidic and alkaline electrolytes, respectively...
May 15, 2018: Nanoscale
https://www.readbyqxmd.com/read/29759653/kinematics-and-kinetics-of-the-shoe-during-human-slips
#12
Arian Iraqi, Rakié Cham, Mark S Redfern, Natasa S Vidic, Kurt E Beschorner
This paper quantified the heel kinematics and kinetics during human slips with the goal of guiding available coefficient of friction (ACOF) testing methods for footwear and flooring. These values were then compared to the testing parameters recommended for measuring shoe-floor ACOF. Kinematic and kinetic data of thirty-nine subjects who experienced a slip incident were pooled from four similar human slipping studies for this secondary analysis. Vertical ground reaction force (VGRF), center of pressure (COP), shoe-floor angle, side-slip angle, sliding speed and contact time were quantified at slip start (SS) and at the time of peak sliding speed (PSS)...
April 25, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29758971/effects-of-dancesport-on-walking-balance-and-standing-balance-among-the-elderly
#13
Jeehoon Sohn, Sung-Ha Park, Sukwon Kim
BACKGROUND: Dancesport is a popular activity among older adults who look for fun and fitness in Korea. Studies reported positive sociological and psychological effects of dancesport. But, little studies were performed to evaluate the effects of dancesport on balance performances. OBJECTIVE: The objective of the present study was to evaluate the effects of dancesport for 15 weeks on walking balance and standing balance of older adults. METHODS: Older adults regularly participated in the dancesport program 3 times a week for 15 weeks...
May 4, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29757620/separation-of-protactinium-employing-sulfur-based-extraction-chromatographic-resins
#14
Tara Mastren, Benjamin W Stein, T Gannon Parker, Valery Radchenko, Roy Copping, Allison Owens, Lance E Wyant, Mark Brugh, Stosh A Kozimor, F Meiring Nortier, Eva R Birnbaum, Kevin D John, Michael Ernst-Heinrich Fassbender
Protactinium-230 (t1/2 17.4 d) is the parent isotope of 230U (t1/2 20.8 d), a radionuclide of interest for targeted alpha therapy (TAT). Column chromatographic methods have been developed to separate no-carrier-added 230Pa from proton irradiated thorium targets and accompanying fission products. Results reported within demonstrate the use of novel sulfur bearing chromatographic extraction resins for the selective separation of protactinium. The recovery yield of 230Pa was 93 ± 4 % employing a R3P=S type commercially available resin and 88 ± 4 % employing a DGTA (diglycothioamide) containing custom synthesized extraction chromatographic resin...
May 14, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29757412/development-of-a-provincial-initiative-to-improve-glucose-control-in-critically-ill-patients
#15
Peter Dodek, Shari McKeown, Eric Young, Vinay Dhingra
Objective: To describe the development, implementation and initial evaluation of an initiative to improve glucose control in critically ill patients. Design: Glucose control in critically ill patients was chosen by critical care leaders as a target for improvement. This was an observational study to document changes in processes and measures of glucose control in each intensive care unit (ICU). ICU nurse educators were interviewed to document relevant changes between April 2012 and April 2016...
May 11, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29755105/current-and-potential-future-seasonal-trends-of-indoor-dwelling-temperature-and-likely-health-risks-in-rural-southern-africa
#16
Thandi Kapwata, Michael T Gebreslasie, Angela Mathee, Caradee Yael Wright
Climate change has resulted in rising temperature trends which have been associated with changes in temperature extremes globally. Attendees of Conference of the Parties (COP) 21 agreed to strive to limit the rise in global average temperatures to below 2 °C compared to industrial conditions, the target being 1.5 °C. However, current research suggests that the African region will be subjected to more intense heat extremes over a shorter time period, with projections predicting increases of 4⁻6 °C for the period 2071⁻2100, in annual average maximum temperatures for southern Africa...
May 10, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29751592/does-type-1-diabetes-modify-sexuality-and-mood-of-women-and-men
#17
Ewelina Bak, Czeslaw Marcisz, Sylwia Krzeminska, Dorota Dobrzyn-Matusiak, Agnieszka Foltyn, Agnieszka Drosdzol-Cop
BACKGROUND: Sexual disorders occurring in women and men with type 1 diabetes have not been sufficiently investigated and described until now. This study attempts to evaluate sexuality in women and men. METHODS: Altogether, the study comprised 115 patients with type 1 diabetes and 105 healthy people constituting the control group. All the studied persons underwent survey studies determining sexuality using the Female Sexual Function Index (FSFI-19) in women and the International Index of Erectile Function (IIEF-15) in men, and the occurrence of depression using the Beck Depression Inventory...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29744927/the-effect-of-bearing-friction-torques-on-the-primary-stability-of-press-fit-acetabular-cups-a-novel-in-vitro-method
#18
Jahnke Alexander, Schroeder Stefan, Fonseca Ulloa Carlos Alfonso, Ahmed Gafar Adam, Ishaque Bernd Alexander, Rickert Markus
Aseptic loosening is the main reason for revision of total hip arthroplasty, and relative micromotions between cementless acetabular cups and bone play an important role regarding their comparatively high loosening rate. Therefore, the aim of the present study was to analyze the influence of resulting frictional torques on the primary stability of press-fit acetabular cups subjected to two different bearing partners. A cementless press-fit cup was implanted in bone-like foam. Primary stability of the cup was analyzed by determining spatial total, translational and rotational interface micromotions by means of an eddy current sensor measuring system...
May 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29742322/targeted-delivery-of-dna-au-nanoparticles-across-the-blood-brain-barrier-using-focused-ultrasound
#19
Ramon Vilar, Tiffany G Chan, Sophie V Morse, Matthew J Copping, James J Choi
Nanoparticles have been widely studied as versatile platforms for in vivo imaging and therapy. However, their use to image and/or treat the brain is limited as they are often unable to cross the blood-brain barrier (BBB). To overcome this problem, herein we report the use of focused ultrasound in vivo to successfully deliver DNA-coated gold nanoparticles to specific locations in the brains of mice.
May 9, 2018: ChemMedChem
https://www.readbyqxmd.com/read/29740634/effectiveness-of-a-nintendo-wii-balance-board-exercise-programme-on-standing-balance-of-children-with-cerebral-palsy-a-randomised-clinical-trial-protocol
#20
Valeska Gatica-Rojas, Ricardo Cartes-Velásquez, Eduardo Guzmán-Muñoz, Guillermo Méndez-Rebolledo, Alex Soto-Poblete, Ana Carolina Pacheco-Espinoza, Carlos Amigo-Mendoza, M Eliana Albornoz-Verdugo, Edith Elgueta-Cancino
Background: Patients with cerebral palsy (CP) typically receive limited physical therapy services. However, the Nintendo Wii system offers a simple and affordable mode of virtual reality therapy. There are no clinical trials assessing the Nintendo Wii balance board for improving standing balance in CP. Methods: This randomised clinical trial will evaluate the effectiveness of an 18-session/six-week protocol using Wii therapy (W-t) compared with conventional therapy (C-t) in Chilean CP patients...
June 2017: Contemporary Clinical Trials Communications
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