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https://www.readbyqxmd.com/read/28813923/a-real-time-and-reduced-complexity-approach-to-the-detection-and-monitoring-of-static-joint-overloading-in-humans
#1
Wansoo Kim, Jinoh Lee, Nikos Tsagarakis, Arash Ajoudani
This paper proposes a novel technique for the real-time estimation of the joint torques variations in humans while performing heavy manipulation tasks. To achieve this, the method is based on the deviations of the Centre of Pressure (CoP) and Ground Reaction Force (GRF) in the presence of interaction forces. The CoP and GRF variations are calculated from the difference between the estimated values (assuming no interaction forces) using a pre-identified statically equivalent serial chain (SESC) and the measured ones (with the effect of interaction forces) using an external device...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813801/therapeutic-effects-of-an-anti-gravity-locomotor-training-alterg-on-postural-balance-and-cerebellum-structure-in-children-with-cerebral-palsy
#2
A H Rasooli, P M Birgani, Sh Azizi, A Shahrokhi, M M Mirbagheri
We evaluated the therapeutic effects of anti-gravity locomotor treadmill (AlterG) training on postural stability in children with Cerebral Palsy (CP) and spasticity, particularly in the lower extremity. AlterG can facilitate walking by reducing the weight of CP children by up to 80%; it can also help subjects maintain an appropriate posture during the locomotor AlterG training. Thus, we hypothesized that AlterG training, for a sufficient period of time, has a potential to produce cerebellum neuroplasticity, and consequently result in an effective permanent postural stability...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811904/concurrence-of-nivolumab-induced-interstitial-lung-disease-and-cancer-invasion
#3
Osamu Kanai, Koichi Nakatani, Kohei Fujita, Misato Okamura, Tadashi Mio
Nivolumab improves overall survival rates of patients with advanced or recurrent non-small-cell lung cancer (NSCLC). Among immune-related adverse events caused by nivolumab, interstitial lung disease (ILD) is a clinically serious and potentially life-threatening toxicity, for which appropriate treatment is needed immediately. However, ILD is sometimes difficult to distinguish from invasive lung adenocarcinoma using only computed tomography (CT) findings. A 71-year-old man was diagnosed with advanced lung adenocarcinoma...
November 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28811573/simultaneous-separation-of-actinium-and-radium-isotopes-from-a-proton-irradiated-thorium-matrix
#4
Tara Mastren, Valery Radchenko, Allison Owens, Roy Copping, Rose Boll, Justin R Griswold, Saed Mirzadeh, Lance E Wyant, Mark Brugh, Jonathan W Engle, Francois M Nortier, Eva R Birnbaum, Kevin D John, Michael E Fassbender
A new method has been developed for the isolation of (223,224,225)Ra, in high yield and purity, from a proton irradiated (232)Th matrix. Herein we report an all-aqueous process using multiple solid-supported adsorption steps including a citrate chelation method developed to remove >99.9% of the barium contaminants by activity from the final radium product. A procedure involving the use of three columns in succession was developed, and the separation of (223,224,225)Ra from the thorium matrix was obtained with an overall recovery yield of 91 ± 3%, average radiochemical purity of 99...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810909/a-multi-center-randomized-controlled-open-label-trial-evaluating-the-effects-of-eosinophil-guided-corticosteroid-sparing-therapy-in-hospitalised-patients-with-copd-exacerbations-the-cortico-steroid-reduction-in-copd-cortico-cop-study-protocol
#5
Pradeesh Sivapalan, Mia Moberg, Josefin Eklöf, Julie Janner, Jørgen Vestbo, Rasmus Rude Laub, Andrea Browatzki, Karin Armbruster, Jon Torgny Wilcke, Niels Seersholm, Ulla Møller Weinreich, Ingrid Louise Titlestad, Helle Frost Andreassen, Charlotte Suppli Ulrik, Uffe Bødtger, Thyge Lynghøj Nielsen, Ejvind Frausing Hansen, Jens Ulrik Stæhr Jensen
BACKGROUND: The most commonly applied treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is a 5-day course of high-dose systemic corticosteroids. However, this treatment has not been shown to reduce mortality and can potentially have serious side effects. Recent research has shown that, presumably, only a subgroup of COPD patients identifieable by blood eosinophil count benefit from a rescue course of prednisolone. By applying a biomarker-guided strategy, the aim of this study is to determine whether it is possible to reduce the use of systemic corticosteroids in AECOPD without influencing the outcome...
August 15, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28809939/a-cross-sectional-study-comparing-lateral-and-diagonal-maximum-weight-shift-in-people-with-stroke-and-healthy-controls-and-the-correlation-with-balance-gait-and-fear-of-falling
#6
Margaretha M van Dijk, Sarah Meyer, Solveig Sandstad, Evelyne Wiskerke, Rhea Thuwis, Chesny Vandekerckhove, Charlotte Myny, Nitesh Ghosh, Hilde Beyens, Eddy Dejaeger, Geert Verheyden
Impaired balance is common post stroke and can be assessed by means of force-platforms measuring center of pressure (COP) displacements during static standing, or more dynamically during lateral maximum weight shift (MWS). However, activities of daily life also include diagonal MWS and since force platforms are nowadays commercially available, investigating lateral and diagonal MWS in a clinical setting might be feasible and clinically relevant. We investigated lateral and diagonal MWS while standing in patients with stroke (PwS) and healthy controls (HC), evaluated MWS towards the affected and the non-affected side for PwS and correlated MWS with measures of balance, gait and fear of falling...
2017: PloS One
https://www.readbyqxmd.com/read/28809814/yerba-mat%C3%A3-ilex-paraguariensis-metabolic-satiety-and-mood-state-effects-at-rest-and-during-prolonged-exercise
#7
Ahmad Alkhatib, Roisin Atcheson
Yerba Maté (YM), has become a popular herb ingested for enhancing metabolic health and weight-loss outcomes. No studies have tested the combined metabolic, satiety, and psychomotor effects of YM during exercise. We tested whether YM ingestion affects fatty acid oxidation (FAO), profile of mood state score (POMS), and subjective appetite scale (VAS), during prolonged moderate exercise. Twelve healthy active females were randomized to ingest either 2 g of YM or placebo (PLC) in a repeated-measures design. Participants rested for 120 min before performing a 30-min cycling exercise corresponding to individuals' crossover point intensity (COP)...
August 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28802428/changes-in-trunk-sway-of-quay-crane-operators-during-work-shift-a-possible-marker-for-fatigue
#8
Bruno Leban, Gianfranco Fancello, Paolo Fadda, Massimiliano Pau
This study investigated changes in task-induced trunk sway of quay crane operators during a four-hour shift performed in a dedicated simulator as an indicator of postural control system effectiveness. Using a pressure sensitive mat placed on the seat pan, center-of-pressure (COP) time series were acquired and processed to calculate sway area, path length and COP displacements and velocities. The results show a well-defined linear trend for sway path and area, with significant increases starting from 65 to 155 min of work respectively...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28802100/influence-of-il-6-il-33-and-tnf-%C3%AE-on-human-mast-cell-activation-lessons-from-single-cell-analysis-by-flow-cytometry
#9
Nathalie Cop, Didier G Ebo, Chris H Bridts, Jessy Elst, Margo M Hagendorens, Christel Mertens, Margaretha A Faber, Luc S De Clerck, Vito Sabato
BACKGROUND: Mechanisms that govern priming and degranulation of human mast cells (MCs) remain elusive. Besides, most of our knowledge is based on experiments from which data only reflect an average of all stimulated cells. This study aims at investigating the effects of proinflammatory cytokines IL-6, IL-33, and TNF-α on IgE-dependent and IgE-independent activation of individual MCs. METHODS: MCs were derived from CD34(+) progenitors isolated from 50 mL whole blood from 4 healthy controls and 5 birch pollen allergic patients...
August 12, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/28800501/learning-effects-of-dynamic-postural-control-by-auditory-biofeedback-versus-visual-biofeedback-training
#10
Naoya Hasegawa, Kenta Takeda, Moe Sakuma, Hiroki Mani, Hiroshi Maejima, Tadayoshi Asaka
Augmented sensory biofeedback (BF) for postural control is widely used to improve postural stability. However, the effective sensory information in BF systems of motor learning for postural control is still unknown. The purpose of this study was to investigate the learning effects of visual versus auditory BF training in dynamic postural control. Eighteen healthy young adults were randomly divided into two groups (visual BF and auditory BF). In test sessions, participants were asked to bring the real-time center of pressure (COP) in line with a hidden target by body sway in the sagittal plane...
August 2, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28799810/acute-effects-of-whole-body-vibration-on-balance-in-persons-with-and-without-chronic-ankle-instability
#11
Nicole K Rendos, Hyung-Pil Jun, Karen Lew Feirman, Kysha Harriell, Sae Yong Lee, Joseph F Signorile
Chronic ankle instability (CAI) is a common condition following ankle injury that is associated with compromised balance. Whole body vibration training (WBVT) programmes are linked with improved balance and function in athletic and non-athletic populations and may improve balance in CAI. Twelve healthy and seven CAI participants completed two randomly assigned interventions. Two Power Plate® platforms were attached back to back using a Theraband®. Participants stood on the active plate and inactive plate for WBVT and sham interventions, respectively...
August 11, 2017: Research in Sports Medicine
https://www.readbyqxmd.com/read/28799352/free-energy-landscape-and-molecular-pathways-of-gas-hydrate-nucleation
#12
Yuanfei Bi, Anna Porras, Tianshu Li
Despite the significance of gas hydrates in diverse areas, a quantitative knowledge of hydrate formation at a molecular level is missing. The impediment to acquiring this understanding is primarily attributed to the stochastic nature and ultra-fine scales of nucleation events, posing a great challenge for both experiment and simulation to explore hydrate nucleation. Here we employ advanced molecular simulation methods, including forward flux sampling (FFS), pB histogram analysis, and backward flux sampling, to overcome the limit of direct molecular simulation for exploring both the free energy landscape and molecular pathways of hydrate nucleation...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28797121/non-alcoholic-fatty-liver-disease-in-mice-with-heterozygous-mutation-in-tmed2
#13
Wenyang Hou, Swati Gupta, Marie-Claude Beauchamp, Libin Yuan, Loydie A Jerome-Majewska
The transmembrane emp24 domain/p24 (TMED) family are essential components of the vesicular transport machinery. Members of the TMED family serve as cargo receptors implicated in selection and packaging of endoplasmic reticulum (ER) luminal proteins into coatomer (COP) II coated vesicles for anterograde transport to the Golgi. Deletion or mutations of Tmed genes in yeast and Drosophila results in ER-stress and activation of the unfolded protein response (UPR). The UPR leads to expression of genes and proteins important for expanding the folding capacity of the ER, degrading misfolded proteins, and reducing the load of new proteins entering the ER...
2017: PloS One
https://www.readbyqxmd.com/read/28796836/colonizing-opportunistic-pathogens-cops-the-beasts-in-all-of-us
#14
Lance B Price, Bruce A Hungate, Benjamin J Koch, Gregg S Davis, Cindy M Liu
No abstract text is available yet for this article.
August 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28795934/strategies-for-developing-family-nursing-communities-of-practice-through-social-media
#15
Kris Isaacson, Wendy S Looman
This discussion article presents communities of practice (CoPs) and bridging social capital as conceptual frameworks to demonstrate how social media can be leveraged for family nursing knowledge, scholarship, and practice. CoPs require a shared domain of interest, exchange of resources, and dedication to expanding group knowledge. Used strategically and with a professional presence, mainstream social media channels such as Twitter, Facebook, and YouTube can support the family nurse in developing and contributing to CoPs related to family nursing...
February 2017: Journal of Family Nursing
https://www.readbyqxmd.com/read/28794630/probiotics-protect-mice-from-cocrmo-particles-induced-osteolysis
#16
Zhenheng Wang, Kaiwen Xue, Maosheng Bai, Zhantao Deng, Jingjing Gan, Gang Zhou, Hongbo Qian, Nirong Bao, Jianning Zhao
Wear particle-induced inflammatory osteolysis is the primary cause of aseptic loosening, which is the most common reason for total hip arthroplasty (THA) failure in the med- and long term. Recent studies have suggested an important role of gut microbiota (GM) in modulating the host metabolism and immune system, leading to alterations in bone mass. Probiotic bacteria administered in adequate amounts can alter the composition of GM and confer health benefits to the host. Given the inflammatory osteolysis that occurs in wear debris-induced prosthesis loosening, we examined whether the probiotic Lactobacillus casei could reduce osteolysis in a mouse calvarial resorption model...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28793888/does-structural-leg-length-discrepancy-affect-postural-control-preliminary-study
#17
Małgorzata Eliks, Wioleta Ostiak-Tomaszewska, Przemysław Lisiński, Paweł Koczewski
BACKGROUND: Leg-length inequality results in an altered position of the spine and pelvis. Previous studies on the influence of leg asymmetry on postural control have been inconclusive. The purpose of this paper was to investigate the effect of structural leg-length discrepancy (LLD) on the control of posture. METHODS: We studied 38 individuals (19 patients with structural LLD, 19 healthy subjects). The examination included measurement of the length of the lower limbs and weight distribution as well as a static posturography...
August 9, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28773917/correlation-factor-study-of-small-punch-creep-test-and-its-life-prediction
#18
Cheng Wen, Tong Xu, Kaishu Guan
A small punch test is one of the innovative methods that can be used to evaluate the properties of a material without destructive harm to the in-service component. Conventionally identifying material properties by a uniaxial test is widely applied to engineering. How the properties obtained from a small punch test can be applied with the same utility has been a goal. In 2006, European Code of Practice (CoP) of small punch tests was first released, in which the correlation factor, ksp, was introduced to bridge the gap between the above methods...
September 24, 2016: Materials
https://www.readbyqxmd.com/read/28772132/effect-of-hearing-aids-on-static-balance-function-in-elderly-with-hearing-loss
#19
Hossein Negahban, Mahtab Bavarsad Cheshmeh Ali, Gholamhossein Nassadj
While a few studies have investigated the relationship between hearing acuity and postural control, little is known about the effect of hearing aids on postural stability in elderly with hearing loss. The aim was to compare static balance function between elderly with hearing loss who used hearing aids and those who did not use. The subjects asked to stand with (A) open eyes on rigid surface (force platform), (B) closed eyes on rigid surface, (C) open eyes on a foam pad, and (D) closed eyes on a foam pad. Subjects in the aided group (n=22) were tested with their hearing aids turned on and hearing aids turned off in each experimental condition...
July 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28767021/the-limits-of-stability-in-patients-with-unilateral-vestibulopathy
#20
Rafael Alvarez-Otero, Nicolas Perez-Fernandez
OBJECTIVE: To characterize the stability limits and region in patients with unilateral vestibulopathy according to the side of the lesion and determine if that imposes any bias. To analyze if the stability limits and region depend on the functional deficit as evaluated in the sensory organization test. METHODS: Forty patients with chronic dizziness and without any vertigo spell for least 6 months prior to testing. In all of them, a unilateral vestibulopathy was diagnosed clinically and at vestibular testing...
October 2017: Acta Oto-laryngologica
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