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Hypertension in pregnancy

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https://www.readbyqxmd.com/read/29157196/perinatal-outcomes-of-hypertensive-disorders-in-pregnancy-at-a-tertiary-hospital-in-ghana
#1
Kwame Adu-Bonsaffoh, Michael Y Ntumy, Samuel A Obed, Joseph D Seffah
BACKGROUND: Hypertensive disorders in pregnancy remain a major global health issue not only because of the associated high adverse maternal outcomes but there is a close accompaniment of significant perinatal morbidity and mortality especially in Sub-Saharan Africa (SSA). However, the perinatal burden of HDP in Ghana has not been explored. We conducted this study to determine the perinatal outcomes of HDP at a tertiary hospital in Ghana. METHODS: A cross-sectional study conducted between January to February 2013 at Korle Bu Teaching Hospital (KBTH) in Accra, Ghana...
November 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29157099/the-association-of-first-trimester-uterine-arteries-doppler-velocimetry-with-different-clinical-phenotypes-of-hypertensive-disorders-of-pregnancy-a-longitudinal-study
#2
Tamara Stampalija, Lorenzo Monasta, Daniela D Di Martino, Mariachiara Quadrifoglio, Leila Lo Bello, Giuseppina D'Ottavio, Sara Zullino, Cristina Mastroianni, Daniela Casati, Valentina Signorelli, Eleonora Rosti, Vera Cecotti, Matteo Ceccarello, Enrico Ferrazzi
INTRODUCTION: Current classification of hypertensive disorders of pregnancy (HDP) is mostly based on temporal classification differentiating HDP according to early and late onset of the disease. However, epidemiological and clinical data suggest that there are two different clinical phenotypes of HDP that coexist at any gestational age: HDP associated to intrauterine growth restriction (HDP-IUGR) and HDP associated to appropriate for gestational age fetal growth (HDP-AGAf). The aim of the study was to evaluate the association of first trimester uterine arteries (UtA) by Doppler velocimetry, and maternal risk factors with HDP according to two different classifications: one based on gestational age at delivery (early- and late-HDP), and one based on longitudinal ultrasound evaluation of fetal growth (HDP-IUGR and HDP-AGAf), independently of the gestational age...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29155965/is-frozen-embryo-transfer-better-for-mothers-and-babies-can-cumulative-meta-analysis-provide-a-definitive-answer
#3
Abha Maheshwari, Shilpi Pandey, Edwin Amalraj Raja, Ashalatha Shetty, Mark Hamilton, Siladitya Bhattacharya
BACKGROUND: Initial observational studies and a systematic review published 5 years ago have suggested that obstetric and perinatal outcomes are better in offspring conceived following frozen rather than fresh embryo transfers, with reduced risks of preterm birth, small for gestational age, low birth weight and pre-eclampsia. More recent primary studies are beginning to challenge some of these findings. We therefore conducted an updated systematic review and cumulative meta-analysis to examine if these results have remained consistent over time...
November 13, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/29153690/time-course-of-angiotensin-ii-dependent-vascular-and-metabolic-effects-of-preeclampsia
#4
Paula Rosas, Cecilia Tufiño, Ismael Bracho Valdes, Rosa A Bobadilla Lugo
Pregnancy is characterized by a blunted pressor response to angiotensin II that is progressively lost during preeclampsia complicated pregnancies. Renin angiotensin system (RAS) plays a pivotal role in cardiovascular and renal function but its role in normal and pathological pregnancy is far from being clarified. It is not as clear if hypertension and particularly pregnancy-induced hypertension as the initial event, can trigger some of the metabolic syndrome components, and if these changes are angiotensin II mediated...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153689/changes-in-echocardiographic-parameters-and-hypertensive-disorders-in-pregnancies-of-women-with-aortic-coarctation
#5
Hiroshi Sato, Chizuko A Kamiya, Masami Sawada, Chinami Horiuchi, Mitsuhiro Tsuritani, Naoko Iwanaga, Hideo Ohuchi, Isao Shiraishi, Hajime Ichikawa, Jun Yoshimatsu
OBJECTIVES: Pregnancy can be well tolerated after the repair of aortic coarctation. However, a higher incidence of hypertensive disorders during these pregnancies was reported. We analyzed the perinatal changes in echocardiographic parameters in women with aortic coarctation and investigated the risk factors of gestational hypertension (GH). METHODS: We retrospectively identified 15 pregnancies in nine Japanese women with aortic coarctation between 1982 and 2015...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153686/progression-of-gestational-hypertension-to-pre-eclampsia-a-cohort-study-of-20-103-pregnancies
#6
Kuo-Hu Chen, Kok-Min Seow, Li-Ru Chen
OBJECTIVE: To investigate previously un-identified risk factors for the progression of gestational hypertension (GH) to pre-eclampsia (PE) by considering Grade III preterm placental calcification (PPC) and excessive weight gain (≧10kgw) at 28weeks gestation. METHODS: At a tertiary teaching hospital, obstetric ultrasonography was performed at 28weeks gestation to establish a diagnosis of grade III PPC. Weight gain during pregnancy was recorded at the same time...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153684/impact-of-maternal-serum-uric-acid-on-perinatal-outcome-in-women-with-hypertensive-disorders-of-pregnancy-a-prospective-study
#7
Naina Kumar, Amit Kant Singh, Bhavya Maini
INTRODUCTION: Worldwide hypertensive disorder of pregnancy is major cause of maternal and perinatal morbidity, mortality. AIM: To study impact of maternal serum uric acid on perinatal outcome in women with hypertensive disorder of pregnancy. METHODOLOGY: Present study was conducted in Obstetrics and Gynecology Department of rural tertiary care centre of Northern India over seven months (October 2016-May 2017). Total 110 pregnant women >-34weeks with hypertensive disorder of pregnancy were divided into three groups; Gestational hypertension (n = 35), Pre-eclampsia (n = 49), Eclampsia (n = 26)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153682/home-blood-pressure-measurement-in-women-with-pregnancy-related-hypertensive-disorders
#8
Patrick G Lan, Jon Hyett, Adrian G Gillin
OBJECTIVES: To determine if home blood pressure measurement (HBPM) provides comparable results to clinic blood pressure (BP) measurement. STUDY DESIGN: A prospective, single-centre study of 37 pregnant and early post-partum women with a hypertensive pregnancy or at high-risk of developing a hypertensive pregnancy were asked to perform HBPM for a minimum period of one week. This was subsequently compared to clinic BP measurement both before and after the period of home measurement...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153681/various-levels-of-circulating-exosomal-total-mirna-and-mir-210-hypoxamir-in-different-forms-of-pregnancy-hypertension
#9
Orsolya Biró, Bálint Alasztics, Attila Molvarec, József Joó, Bálint Nagy, János Rigó
INTRODUCTION: Hypertension is a common complication during pregnancy, affecting 10% of pregnant women worldwide. Several microRNA (miRNA) were shown to be involved in hypertensive disorders of pregnancy. In preeclampsia (PE), placental dysfunction causes the enhanced release of extracellular vesicle-derived miRNAs. The hypoxia-sensitive hsa-mir-210 is the most common PE-associated miRNA, but its exosomal profile has not been investigated. OBJECTIVES: Our aims were to measure exosomal total-miRNA concentration and to perform expression analysis of circulating exosomal hsa-miR-210 in women affected by chronic hypertension (CHT) gestational hypertension (GHT) or PE...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153679/hypertensive-disorders-of-pregnancy-in-women-with-gestational-diabetes-mellitus-from-rio-de-janeiro-brazil
#10
Luciana Lourenço Gomes Dos Santos da Silva, Cláudia Saunders, Aline Bull Ferreira Campos, Gabriella Pinto Belfort, Patricia de Carvalho Padilha, Rosangela Alves Pereira, Rita Guérios Bornia
Pregnant women with Gestational Diabetes Mellitus (GDM) have a greater chance of developing Hypertensive Disorders of Pregnancy (HDP) by the effect of insulin resistance in nitric oxide action.This study aims to describe factors associated with the development of HDP in pregnant women with GDM, assisted in a public maternity hospital in Rio de Janeiro, Brazil. This is a cross-sectional study including 292 pregnant adult women with GDM assisted at Maternidade Escola of the Universidade Federal do Rio de Janeiro...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153677/the-efficacy-of-peripartum-transthoracic-echocardiography-in-women-with-preeclampsia
#11
Sae Kyung Choi, Jong Chul Shin, Yong Gyu Park, In Yang Park, Ji Young Kwon, Hyun Sun Ko, Yeon Hee Kim
OBJECTIVE: To examine the features and efficacy of transthoracic echocardiography (TTE) in preeclampsia. METHODS: We retrospectively reviewed the medical records of 145 pregnant women with preeclampsia, who underwent TTE at Seoul St. Mary's Hospital between July 2006 and June 2016. We analyzed echocardiographic features in preeclampsia and the relationship between the severity of preeclampsia and TTE findings. Additionally, we examined the predictive echocardiographic factors of persistent hypertension and calculated the adjusted odds ratio (OR) and 95% confidence interval (CI) for multiple regression models by considering systolic and diastolic blood pressure and pre-pregnancy body mass index (BMI)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153674/labor-therapeutics-and-bmi-as-risk-factors-for-postpartum-preeclampsia-a-case-control-study
#12
Geraldine Skurnik, Shelley Hurwitz, Thomas F McElrath, Lawrence C Tsen, Stacey Duey, Aditi R Saxena, Ananth Karumanchi, Janet W Rich-Edwards, Ellen W Seely
OBJECTIVES: This study aims at identifying associations between therapeutics used during labor and the occurrence of postpartum preeclampsia (PPPE), a poorly understood entity. STUDY DESIGN AND MAIN OUTCOME MEASURES: This is a case-control study of women who received an ICD-9 code for PPPE (cases) during the years 2009-2011, compared to women with a normotensive term pregnancy, delivery and postpartum period until discharge (controls), matched on age (±1year) and delivery date (±3months)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153673/pregnancy-complications-and-later-vascular-ultrasound-measures-a-cohort-study
#13
Emily W Harville, Markus Juonala, Jorma S A Viikari, Mika Kähönen, Olli T Raitakari
OBJECTIVES: Pregnancy complications predict or even predispose to later cardiovascular disease in the mother. We examined whether pregnancy complications are associated with post-pregnancy measures of endothelial dysfunction and arterial stiffness. STUDY DESIGN: Prospective cohort; Data for 847 women female participants in the Cardiovascular Risk in Young Finns study were linked with the national birth registry. Preterm birth (<37weeks), low birthweight (<2500g), small-for-gestational-age (weight <10th percentile for gestational age), and hypertensive disorders of pregnancy were examined as predictors of later vascular measures...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153666/prevalence-risk-factors-and-associated-complications-of-postpartum-hypertension-in-rural-haiti
#14
Eleanor Kang, Rebekah Sugarman, Hadi Ramadan, Ariel Mueller, Sana Shahul, Joana Lopes Perdigao, David Jean Louis, Rulx Narcisse, Herriot Sannon, Laura Magee, Sarosh Rana
BACKGROUND: The prevalence of hypertensive disorders during pregnancy is high in developing countries such as Haiti, however little is known about postpartum hypertension (PPHTN). METHODS: This is a prospective study done at Hospital Albert Schweitzer in rural Haiti among pregnant women age 18 or older who were admitted for labor. Blood pressures were collected before and after delivery and medical charts were reviewed to gather delivery characteristics and fetal/neonatal outcomes...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153665/correlation-between-maternal-body-composition-and-haemodynamic-changes-in-pregnancy-different-profiles-for-different-hypertensive-disorders
#15
I Pisani, G M Tiralongo, D Lo Presti, G Gagliardi, D Farsetti, B Vasapollo, G P Novelli, A Andreoli, H Valensise
OBJECTIVES: To assess and correlate changes in body composition and haemodynamic function during pregnancy. To identify different haemodynamic profiles based on the onset of hypertensive diseases such as gestational hypertension and preeclampsia. METHODS: We enrolled 265 healthy, normotensive pregnant women throughout pregnancy (from 6+0 to 36+0weeks). They were subjected to assessment of body composition and haemodynamic function using non-invasive methods. We divided our population in three groups: group A with physiological pregnancy, group B with gestational hypertension and group C with preeclamptic patients...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153663/prognostic-model-for-chronic-hypertension-in-women-with-a-history-of-hypertensive-pregnancy-disorders-at-term
#16
V S Visser, W Hermes, J Twisk, A Franx, M G van Pampus, C Koopmans, B W J Mol, C J M de Groot
INTRODUCTION: The association between hypertensive pregnancy disorders and cardiovascular disease later in life is well described. In this study we aim to develop a prognostic model from patients characteristics known before, early in, during and after pregnancy to identify women at increased risk of cardiovascular disease e.g. chronic hypertension years after pregnancy complicated by hypertension at term. METHODS: We included women with a history of singleton pregnancy complicated by hypertension at term...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153660/fetal-size-and-growth-velocity-in-chronic-hypertension
#17
T Frusca, S Parolini, A Dall'Asta, W A Hassan, A Vitulo, A Gillett, D Pasupathy, C C Lees
OBJECTIVE: To investigate longitudinal fetal growth and growth velocity for commonly measured biometric parameters in women with chronic hypertension. METHODS: Two centre retrospective European study of women with chronic hypertension ascertained at pregnancy booking. Ultrasound measurements of head circumference (HC), abdominal circumference (AC) and femur length (FL) were used to derive longitudinal fetal growth charts derived using functional linear discriminant analysis (FLDA)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153659/a-simple-clinical-method-to-identify-women-at-higher-risk-of-preeclampsia
#18
Effie Viguiliouk, Alison L Park, Howard Berger, Michael P Geary, Joel G Ray
An outstanding issue is how to efficiently identify women at high risk of preeclampsia. This retrospective cohort study included 8672 pregnancies at a single centre in Toronto. We tested our simple method - presence vs. absence of≥1 major (pre-pregnancy BMI>30kg/m(2), chronic hypertension, pre-pregnancy diabetes mellitus and assisted reproductive therapy) or≥2 minor (prior stillbirth, age>40years, nulliparity, multifetal pregnancy, chronic kidney disease, and SLE) risk factors for PE. The RR of PE was 8...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153658/neurological-function-in-children-born-to-preeclamptic-and-hypertensive-mothers-a-systematic-review
#19
REVIEW
Ernesto A Figueiró-Filho, Lauren E Mak, James N Reynolds, Patrick W Stroman, Graeme N Smith, Nils D Forkert, Angelina Paolozza, Matthew T Rätsep, B Anne Croy
BACKGROUND: Offspring whose mothers developed preeclampsia (PE-F1s) show developmental effects that are now being identified, such as cognitive, behavioural, and mood differences compared to offspring from non-complicated pregnancies. We hypothesize that the progressive angiokine dysregulation associated with development of preeclampsia (PE) reflects gene dysregulation in pre-implantation conceptuses, and manifests in all developing fetal tissues rather than exclusively to the placenta...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29150215/lifestyles-guide-and-glaucoma-ii-diet-supplements-drugs-sleep-pregnancy-and-systemic-hypertension
#20
A Antón-López, J Moreno-Montañés, S Duch-Tuesta, P Corsino Fernández-Vila, J García-Feijoo, E Millá-Griñó, F J Muñoz-Negrete, L Pablo-Júlvez, I Rodríguez-Agirretxe, J L Urcelay-Segura, F Ussa-Herrera, M P Villegas-Pérez
PURPOSE: To establish evidence based guidelines to advise patients on the relationship between habits, diet, certain circumstances, diseases and glaucoma. METHODS: Review of all published articles on glaucoma and sports or other activities. The papers were classified according to the level of scientific evidence based on the Oxford Centre for Evidence-based Medicine classification. RESULTS: The evidence on the relationship between diet or supplements and the incidence or progression of glaucoma is insufficient to make a general recommendation for glaucoma patients...
November 14, 2017: Archivos de la Sociedad Española de Oftalmología
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