Yiyang Luo, Hailin Wang, Lijun Wang, Wei Wu, Jiale Zhao, Xueqing Li, Ruisi Xiong, Xueliang Ding, Ding Yuan, Chengfu Yuan
BACKGROUND: Non-coding RNA is a type of RNA that does not encode proteins, distributed among rRNA, tRNA, snRNA, snoRNA, microRNA and other RNAs with identified functions, where the Long non-coding RNA (lncRNA) displays a nucleotide length over 200. LncRNAs enable multiple biological processes in the human body, including cancer cell invasion and metastasis, apoptosis, cell autophagy, inflammation, etc. Recently, a growing body of studies has demonstrated the association of lncRNAs with obesity and obesity-induced insulin resistance and NAFLD, where MEG3 is related to glucose metabolism, such as insulin resistance...
October 19, 2023: Current Medicinal Chemistry