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Karl Jung

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https://www.readbyqxmd.com/read/28095900/post-stroke-dementia-a-comprehensive-review
#1
REVIEW
Milija D Mijajlović, Aleksandra Pavlović, Michael Brainin, Wolf-Dieter Heiss, Terence J Quinn, Hege B Ihle-Hansen, Dirk M Hermann, Einor Ben Assayag, Edo Richard, Alexander Thiel, Efrat Kliper, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee, Osman Sinanović, Deborah A Levine, Ilana Schlesinger, Gillian Mead, Vuk Milošević, Didier Leys, Guri Hagberg, Marie Helene Ursin, Yvonne Teuschl, Semyon Prokopenko, Elena Mozheyko, Anna Bezdenezhnykh, Karl Matz, Vuk Aleksić, DafinFior Muresanu, Amos D Korczyn, Natan M Bornstein
Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one third of stroke survivors. Various definitions of PSCI and PSD have been described. We propose PSD as a label for any dementia following stroke in temporal relation. Various tools are available to screen and assess cognition, with few PSD-specific instruments. Choice will depend on purpose of assessment, with differing instruments needed for brief screening (e.g., Montreal Cognitive Assessment) or diagnostic formulation (e...
January 18, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28094455/body-regions-have-an-impact-on-the-collagen-elastin-index-of-the-skin-measured-by-non-invasive-in-vivo-vertical-two-photon-microscopy
#2
Carolin Czekalla, Karl Heinz Schönborn, Nadine Döge, Sora Jung, Maxim E Darvin, Jürgen Lademann, Martina C Meinke
No abstract text is available yet for this article.
January 17, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28032815/the-digest
#3
Rachel Arnold, Angela Coppola, Thomas Curran, Lori Dithurbide, Karl Erickson, Mary Jung, Lindsay Kipp, Larkin Lamarche, Luc Martin, Kathleen Wilson
No abstract text is available yet for this article.
October 2016: Journal of Sport & Exercise Psychology
https://www.readbyqxmd.com/read/28026402/the-digest
#4
Rachel Arnold, Angela Coppola, Thomas Curran, Lori Dithurbide, Karl Erickson, Mary Jung, Lindsay Kipp, Larkin Lamarche, Luc Martin, Kathleen Wilson
No abstract text is available yet for this article.
August 2016: Journal of Sport & Exercise Psychology
https://www.readbyqxmd.com/read/28008226/preparation-and-physicochemical-characterization-of-spray-dried-and-jet-milled-microparticles-containing-bosentan-hydrate-for-dry-powder-inhalation-aerosols
#5
Hyo-Jung Lee, Ji-Hyun Kang, Hong-Goo Lee, Dong-Wook Kim, Yun-Seok Rhee, Ju-Young Kim, Eun-Seok Park, Chun-Woong Park
The objectives of this study were to prepare bosentan hydrate (BST) microparticles as dry powder inhalations (DPIs) via spray drying and jet milling under various parameters, to comprehensively characterize the physicochemical properties of the BST hydrate microparticles, and to evaluate the aerosol dispersion performance and dissolution behavior as DPIs. The BST microparticles were successfully prepared for DPIs by spray drying from feeding solution concentrations of 1%, 3%, and 5% (w/v) and by jet milling at grinding pressures of 2, 3, and 4 MPa...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27861524/factors-associated-with-worse-lung-function-in-cystic-fibrosis-patients-with-persistent-staphylococcus-aureus
#6
Sibylle Junge, Dennis Görlich, Martijn den Reijer, Bärbel Wiedemann, Burkhard Tümmler, Helmut Ellemunter, Angelika Dübbers, Peter Küster, Manfred Ballmann, Cordula Koerner-Rettberg, Jörg Große-Onnebrink, Eberhardt Heuer, Wolfgang Sextro, Jochen G Mainz, Jutta Hammermann, Joachim Riethmüller, Ute Graepler-Mainka, Doris Staab, Bettina Wollschläger, Rüdiger Szczepanski, Antje Schuster, Friedrich-Karl Tegtmeyer, Sivagurunathan Sutharsan, Alexandra Wald, Jerzy-Roch Nofer, Willem van Wamel, Karsten Becker, Georg Peters, Barbara C Kahl
BACKGROUND: Staphylococcus aureus is an important pathogen in cystic fibrosis (CF). However, it is not clear which factors are associated with worse lung function in patients with persistent S. aureus airway cultures. Our main hypothesis was that patients with high S. aureus density in their respiratory specimens would more likely experience worsening of their lung disease than patients with low bacterial loads. METHODS: Therefore, we conducted an observational prospective longitudinal multi-center study and assessed the association between lung function and S...
2016: PloS One
https://www.readbyqxmd.com/read/27746184/ck2%C3%AE-csnk2a1-phosphorylates-sirt6-and-is-involved-in-the-progression-of-breast-carcinoma-and-predicts-shorter-survival-of-breast-carcinoma-patients
#7
Jun Sang Bae, See-Hyoung Park, Urangoo Jamiyandorj, Kyoung Min Kim, Sang Jae Noh, Jung Ryul Kim, Hye Jeong Park, Keun Sang Kwon, Sung Hoo Jung, Ho Sung Park, Byung-Hyun Park, Ho Lee, Woo Sung Moon, Karl G Sylvester, Kyu Yun Jang
Recently, the roles of sirtuins (SIRTs) in tumorigenesis have been of interest to oncologists, and casein kinase 2 α1 (CSNK2A1) has been shown to be involved in tumorigenesis by phosphorylating various proteins, including SIRT1. Therefore, we evaluated the roles of CSNK2A1, SIRT6, and phosphorylated SIRT6 and their relationships in breast carcinoma. Nuclear expression of CSNK2A1 and SIRT6 predicted shorter overall survival and relapse-free survival by multivariate analysis. Inhibition of CSNK2A1 decreased the proliferative and invasive activity of cancer cells...
October 13, 2016: American Journal of Pathology
https://www.readbyqxmd.com/read/27720205/a-novel-conformal-superficial-high-dose-rate-brachytherapy-device-for-the-treatment-of-nonmelanoma-skin-cancer-and-keloids
#8
Clara Ferreira, Daniel Johnson, Karl Rasmussen, Clinton Leinweber, Salahuddin Ahmad, Jae Won Jung
PURPOSE: To develop a novel conformal superficial brachytherapy (CSBT) device as a treatment option for the patient-specific radiation therapy of conditions including superficial lesions, postsurgical positive margins, Dupuytren's contractures, keloid scars, and complex anatomic sites (eyelids, nose, ears, etc.). METHODS AND MATERIALS: A preliminary CSBT device prototype was designed, built, and tested using readily available radioactive seeds. Iodine-125 ((125)I) seeds were independently guided to the treatment surface to conform to the target...
October 3, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27705030/staff-perceptions-of-collaboration-on-a-new-interprofessional-unit-using-the-assessment-of-interprofessional-team-collaboration-scale-aitcs
#9
Dawn Prentice, Bonny Jung, Karyn Taplay, Karl Stobbe, Lisa Hildebrand
The aim of this study was to obtain baseline information on staff attitudes and perceptions of interprofessional collaboration on a newly formed interprofessional education unit. The Assessment of Interprofessional Team Collaboration Scale (AITCS) was administered to 54 interprofessional team members on a 30-bed medical interprofessional education (IPE) unit. We found that the team members respected each other but felt they needed more organisational support to further develop team skills. Additionally, team members noted that they did not have enough time for team reflection or to make changes to the team processes...
November 2016: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/27689917/generating-aptamers-interacting-with-polymeric-surfaces-for-biofunctionalization
#10
Christian Schulz, Jochen Hecht, Anne Krüger-Genge, Karl Kratz, Friedrich Jung, Andreas Lendlein
Common strategies for biofunctionalization of surfaces comprise the immobilization of bioactive molecules used as cell-binding ligands for cell recruitment. Besides covalent binding, multivalent noncovalent physical forces between substrate and ligand are an alternative way to equip surfaces with biomacromolecules. In this study, polymer binding ligands are screened by means of a DNA-based in vitro selection process. As candidate biomaterials poly(ether imide) (PEI), polystyrene, and poly[ethylene-co-(vinyl acetate)] are selected, due to their different chemical structure, but similar macroscopic interface properties, allowing physical interaction with nucleotide bases by varying valences...
December 2016: Macromolecular Bioscience
https://www.readbyqxmd.com/read/27554144/potential-transfer-of-extended-spectrum-%C3%AE-lactamase-encoding-gene-blashv18-gene-between-klebsiella-pneumoniae-in-raw-foods
#11
Yangjin Jung, Karl R Matthews
This study investigated the transfer frequency of the extended-spectrum β-lactamase-encoding gene (blaSHV18) among Klebsiella pneumoniae in tryptic soy broth (TSB), pasteurized milk, unpasteurized milk, alfalfa sprouts and chopped lettuce at defined temperatures. All transconjugants were characterized phenotypically and genotypically. KP04(ΔKM) and KP08(ΔKM) isolated from seed sprouts and KP342 were used as recipients in mating experiments with K. pneumoniae ATCC 700603 serving as the donor. In mating experiments, no transconjugants were detected at 4 °C in liquid media or chopped lettuce, but detected in all media tested at 15 °C, 24 °C, and 37 °C...
December 2016: Food Microbiology
https://www.readbyqxmd.com/read/27532207/comparative-genomics-and-metabolic-analysis-reveals-peculiar-characteristics-of-rhodococcus-opacus-strain-m213-particularly-for-naphthalene-degradation
#12
Ashish Pathak, Ashvini Chauhan, Jochen Blom, Karl J Indest, Carina M Jung, Paul Stothard, Gopal Bera, Stefan J Green, Andrew Ogram
The genome of Rhodococcus opacus strain M213, isolated from a fuel-oil contaminated soil, was sequenced and annotated which revealed a genome size of 9,194,165 bp encoding 8680 putative genes and a G+C content of 66.72%. Among the protein coding genes, 71.77% were annotated as clusters of orthologous groups of proteins (COGs); 55% of the COGs were present as paralog clusters. Pulsed field gel electrophoresis (PFGE) analysis of M213 revealed the presence of three different sized replicons- a circular chromosome and two megaplasmids (pNUO1 and pNUO2) estimated to be of 750Kb 350Kb in size, respectively...
2016: PloS One
https://www.readbyqxmd.com/read/27521557/-smoker-s-paradox-in-patients-with-cardiogenic-shock-complicating-myocardial-infarction-a-substudy-of-the-iabp-shock-ii-trial-and-registry
#13
Mohammed Saad, Georg Fuernau, Steffen Desch, Ingo Eitel, Christian Jung, Janine Pöss, Steffen Schneider, Gerhard Schuler, Karl Werdan, Uwe Zeymer, Holger Thiele
BACKGROUND: Several studies in patients with acute myocardial infarction (AMI) without cardiogenic shock (CS) indicate a better survival in smokers, the so called "smoker's paradox". For CS, this relationship has not been investigated so far in the primary percutaneous coronary intervention (PCI) era. METHODS: In a predefined substudy of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial and its accompanying registry including patients with CS complicating AMI we investigated differences in outcome of smokers compared to non-smokers...
November 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27488957/rhodococcus-jostii-rha1-tada-homolog-deletion-mutants-accumulate-less-polyhydroxyalkanoates-phas-than-the-parental-strain
#14
Karl J Indest, Jed O Eberly, Dawn E Hancock, Carina M Jung, Matthew R Carr, Gary A Blakeney
No abstract text is available yet for this article.
September 12, 2016: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/27378612/culprit-lesion-location-and-outcome-in-patients-with-cardiogenic-shock-complicating-myocardial-infarction-a-substudy-of-the-iabp-shock-ii-trial
#15
Georg Fuernau, Karl Fengler, Steffen Desch, Ingo Eitel, Franz-Josef Neumann, Hans-Georg Olbrich, Antoinette de Waha, Suzanne de Waha, Gert Richardt, Marcus Hennersdorf, Klaus Empen, Rainer Hambrecht, Christian Jung, Michael Böhm, Janine Pöss, Ruth H Strasser, Steffen Schneider, Taoufik Ouarrak, Gerhard Schuler, Karl Werdan, Uwe Zeymer, Holger Thiele
BACKGROUND: In myocardial infarction without cardiogenic shock (CS), the affected coronary vessel has significant influence on the final infarct size and patient prognosis. CS data on this relation are scarce. The objective of this study was to determine the prognostic relevance of the culprit lesion location in patients with CS complicating acute myocardial infarction. METHODS: In the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial patients with CS were randomized to therapy with intraaortic balloon pump or control...
December 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27301804/evaluation-of-biostimulation-and-bioaugmentation-to-stimulate-hexahydro-1-3-5-trinitro-1-3-5-triazine-degradation-in-an-aerobic-groundwater-aquifer
#16
Mandy M Michalsen, Aaron S King, Rebecca A Rule, Mark E Fuller, Paul B Hatzinger, Charles W Condee, Fiona H Crocker, Karl J Indest, Carina M Jung, Jack D Istok
Hexahydro-1,3,5-trinitro-1,3,5,-triazine (RDX) is a toxic and mobile groundwater contaminant common to military sites. This study compared in situ RDX degradation rates following bioaugmentation with Gordonia sp. strain KTR9 (henceforth KTR9) to rates under biostimulation conditions in an RDX-contaminated aquifer in Umatilla, OR. Bioaugmentation was achieved by injecting site groundwater (6000 L) amended with KTR9 cells (10(8) cells mL(-1)) and low carbon substrate concentrations (<1 mM fructose) into site wells...
July 19, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27280140/interprofessional-practice-in-health-care-an-educational-project-with-four-learning-sequences-for-students-from-six-study-programs
#17
Anna Christina Nowak, Kathrin Klimke-Jung, Thorsten Schäfer, Karl Reif
INTRODUCTION: In response to demographic changes and the growing complexity of healthcare demands, national and international organizations are requiring greater cooperation among the health professions. Implementation of interprofessional learning programs within study programs in medicine, midwifery, nursing, and therapy is still rare. The first projects are currently underway in Germany. This paper presents the experience gathered by the organizers as interprofessional courses for six study programs were implemented...
2016: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/27139938/solo-surgeon-retroauricular-approach-endoscopic-thyroidectomy
#18
Doh Young Lee, Seung-Kuk Baek, Kwang-Yoon Jung
BACKGROUND: This study aimed to evaluate the feasibility and efficacy of solo-surgeon retroauricular thyroidectomy. MATERIALS AND METHODS: For solo-surgery, we used an Endoeye Flex Laparo-Thoraco Videoscope (Olympus America, Inc.). A Vitom Karl Storz holding system (Karl Storz GmbH & Co.) composed of several bars connected by a ball-joint system was used for fixation of endoscope. A snake retractor and a brain-spoon retractor were used on the sternocleidomastoid...
January 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27033535/metagenomic-analysis-of-denitrifying-wastewater-enrichment-cultures-able-to-transform-the-explosive-3-nitro-1-2-4-triazol-5-one-nto
#19
Jed O Eberly, Karl J Indest, Dawn E Hancock, Carina M Jung, Fiona H Crocker
Removal of 3-nitro-1,2,4-triazol-5-one (NTO) was investigated in conjunction with heterotrophic and autotrophic denitrifying growth conditions by a microbial consortium from a wastewater treatment plant. Microcosms were supplemented with molasses, methanol, or thiosulfate. Cultures were passaged twice by transferring 10 % of the culture volume to fresh media on days 11 and 21. Rates of NTO removal were 18.71 ± 0.65, 9.04 ± 2.61, and 4.34 ± 2.72 mg/L/day while rates of nitrate removal were 20.08 ± 1...
June 2016: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/26956048/diagnostic-and-clinical-relevance-of-the-autophago-lysosomal-network-in-human-gliomas
#20
Lukas Jennewein, Michael W Ronellenfitsch, Patrick Antonietti, Elena I Ilina, Jennifer Jung, Daniela Stadel, Lisa-Marie Flohr, Jenny Zinke, Janusz von Renesse, Ulrich Drott, Peter Baumgarten, Anne K Braczynski, Cornelia Penski, Michael C Burger, Jean-Philippe Theurillat, Joachim P Steinbach, Karl-Heinz Plate, Ivan Dikic, Simone Fulda, Christian Brandts, Donat Kögel, Christian Behrends, Patrick N Harter, Michel Mittelbronn
Recently, the conserved intracellular digestion mechanism 'autophagy' has been considered to be involved in early tumorigenesis and its blockade proposed as an alternative treatment approach. However, there is an ongoing debate about whether blocking autophagy has positive or negative effects in tumor cells. Since there is only poor data about the clinico-pathological relevance of autophagy in gliomas in vivo, we first established a cell culture based platform for the in vivo detection of the autophago-lysosomal components...
April 12, 2016: Oncotarget
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