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Radiation bowel disease

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https://www.readbyqxmd.com/read/28203370/abdominal-adhesions-a-practical-review-of-an-often-overlooked-entity
#1
REVIEW
N Tabibian, E Swehli, A Boyd, A Umbreen, J H Tabibian
Formation of intra-abdominal adhesions is a common consequence of abdomino-pelvic surgery, radiation therapy, and inflammatory processes. In a small but clinically significant proportion of patients, adhesive disease may develop, wherein adhesions lead to a variety of chronic symptoms such as abdominal distension, pain, nausea, and abnormal bowel movement pattern which can be daily, intermittent, or episodic. Due to the chronic and troublesome nature of these symptoms, adhesive disease may be life-altering in many patients, particularly when not recognized and appropriately addressed, as is the case not infrequently...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28185689/imaging-of-acute-pelvic-pain-in-girls-ovarian-torsion-and-beyond-%C3%A2
#2
REVIEW
Lena Naffaa, Tejaswini Deshmukh, Shanthan Tumu, Chris Johnson, Kevin P Boyd, Arthur B Meyers
: Identifying the etiology of acute pelvic pain in girls is often clinically challenging. Particularly in young girls, it is often difficult to determine if acute pelvic symptoms are originating from a gynecologic source or from a genitourinary or gastrointestinal etiology based on the child's clinical examination alone. Therefore, imaging plays a key role in establishing a diagnosis and in directing medical and surgical treatment. Pediatric gynecologic conditions, which can present acutely with pain or mass or both include ovarian torsion, hematometrocolpos, pelvic inflammatory disease, inguinal hernias containing an ovary or the uterus or both, adnexal cysts, pregnancy, vaginal foreign bodies, and ovarian vein thrombosis...
December 21, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28158314/identifying-radiation-induced-survivorship-syndromes-affecting-bowel-health-in-a-cohort-of-gynecological-cancer-survivors
#3
Gunnar Steineck, Viktor Skokic, Fei Sjöberg, Cecilia Bull, Eleftheria Alevronta, Gail Dunberger, Karin Bergmark, Ulrica Wilderäng, Jung Hun Oh, Joseph O Deasy, Rebecka Jörnsten
BACKGROUND: During radiotherapy unwanted radiation to normal tissue surrounding the tumor triggers survivorship diseases; we lack a nosology for radiation-induced survivorship diseases that decrease bowel health and we do not know which symptoms are related to which diseases. METHODS: Gynecological-cancer survivors were followed-up two to 15 years after having undergone radiotherapy; they reported in a postal questionnaire the frequency of 28 different symptoms related to bowel health...
2017: PloS One
https://www.readbyqxmd.com/read/28129973/acute-toxicity-and-its-dosimetric-correlates-for-high-risk-prostate-cancer-treated-with-moderately-hypofractionated-radiotherapy
#4
Moses Arunsingh, Indranil Mallick, Sriram Prasath, B Arun, Sandip Sarkar, Raj Kumar Shrimali, Sanjoy Chatterjee, Rimpa Achari
AIMS: To report the acute toxicity and the dosimetric correlates after moderately hypofractionated radiotherapy for localized prostate cancer. METHODS: A total of 101 patients with localized prostate cancer were treated with image-guided intensity-modulated radiation therapy. Patients were treated to 65Gy/25Fr/5 weeks (n = 18), or 60Gy/20Fr/4 weeks (n = 83). Most (82.2%) had high-risk or pelvic node-positive disease. Acute toxicity was assessed using Radiation Therapy Oncology Group (RTOG) acute morbidity scoring criteria...
January 24, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28110975/a-prospective-study-of-health-related-quality-of-life-outcomes-for-patients-with-low-risk-prostate-cancer-managed-by-active-surveillance-or-radiation-therapy
#5
John S Banerji, Lauren M Hurwitz, Jennifer Cullen, Erika M Wolff, Katherine E Levie, Inger L Rosner, Timothy C Brand, James O LʼEsperance, Joseph R Sterbis, Christopher R Porter
INTRODUCTION: Patients with low-risk prostate cancer (PCa) often have excellent oncologic outcomes. However, treatment with curative intent can lead to decrements in health-related quality of life (HRQoL). Patients treated with radical prostatectomy have been shown to suffer declines in urinary and sexual HRQoL as compared to those managed with active surveillance (AS). Similarly, patients treated with external-beam radiation therapy (EBRT) are hypothesized to experience greater declines in bowel HRQoL...
January 19, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28105159/small-bowel-metastasis-from-pancreatic-cancer-in-a-long-term-survival-patient-with-synchronous-advanced-malignant-pleural-mesothelioma-a-case-report-and-literature-review
#6
Morena Fasano, Carminia Maria Della Corte, Giovanni Vicidomini, Valerio Scotti, Pier Francesco Rambaldi, Alfonso Fiorelli, Marina Accardo, Ferdinando De Vita, Mario Santini, Fortunato Ciardiello, Floriana Morgillo
Diffuse malignant pleural mesothelioma (MPM) is an aggressive tumor that originates from the surface of the pleura. Approximately 70% of cases are associated with chronic asbestos exposure. MPM is regarded as an incurable disease, with a median survival of ~2 years following intensive multimodality treatment. Pancreatic cancer is a malignancy also associated with a poor prognosis, with only 2% of patients surviving for 5 years. The majority of patients with pancreatic cancer are diagnosed with an advanced stage of disease and experience a poor response to therapy...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28049025/correction-of-vitamin-d-deficiency-using-sublingually-administered-vitamin-d2-in-a-crohn-s-disease-patient-with-mal-absorption-and-a-new-ileostomy
#7
REVIEW
Patrick McCullough, Robert Heaney
Vitamin D deficiency has been shown to be associated with many adverse health problems. Studies have shown that patients with Crohn's disease who have low vitamin D levels have a poorer quality of life than those with more adequate levels. It has also been shown that patients with mal-absorption problems have a difficult time achieving normal vitamin D levels in spite of aggressive supplementation, and that exposure to UVB radiation may be the most effective treatment option for these patients. We present a case in which 25-hydroxyvitamin D levels were normalized within 2 weeks in a severely vitamin D deficient patient with Crohn's disease with mal-absorption and a new ileostomy, utilizing sublingually administered vitamin D2...
December 31, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28018097/contraindications-for-video-capsule-endoscopy
#8
REVIEW
Dirk Bandorski, Niehls Kurniawan, Peter Baltes, Reinhard Hoeltgen, Matthias Hecker, Dominik Stunder, Martin Keuchel
Video capsule endoscopy (VCE) has been applied in the last 15 years in an increasing field of applications. Although many contraindications have been put into perspective, some precautions still have to be considered. Known stenosis of the gastrointestinal tract is a clear contraindication for VCE unless surgery is already scheduled or at least has been considered as an optional treatment modality. In patients with a higher incidence of stenosis, as in an established diagnosis of Crohn's disease, clinical signs of obstruction, prior radiation or surgical small bowel resection, a preceding test with the self-dissolving patency capsule can override this contraindication...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28001303/predictors-of-multidomain-decline-in-health-related-quality-of-life-after-stereotactic-body-radiation-therapy-sbrt-for-prostate-cancer
#9
Robert T Dess, William C Jackson, Simeng Suy, Payal D Soni, Jae Y Lee, Ahmed E Abugharib, Zachary S Zumsteg, Felix Y Feng, Daniel A Hamstra, Sean P Collins, Daniel E Spratt
BACKGROUND: Stereotactic body radiation therapy (SBRT) for localized prostate cancer involves high-dose-per-fraction radiation treatments. Its use is increasing, but concerns remain about treatment-related toxicity. The authors assessed the incidence and predictors of a global decline in health-related quality of life (HRQOL) after prostate SBRT. METHODS: From 2008 to 2014, 713 consecutive men with localized prostate cancer received treatment with SBRT according to a prospective institutional protocol...
December 21, 2016: Cancer
https://www.readbyqxmd.com/read/27943484/utility-of-mr-enterography-and-ultrasound-for-the-investigation-of-small-bowel-crohn-s-disease
#10
REVIEW
Gauraang Bhatnagar, Conrad Von Stempel, Steve Halligan, Stuart A Taylor
: Cross sectional Imaging plays an increasingly important role the diagnosis and management of Crohn's disease. Particular emphasis is placed on MRI and Ultrasound as they do not impart ionising radiation. Both modalities have reported high sensitivity for disease detection, activity assessment and evaluation of extra-luminal complications, and have positive effects on clinical decision making. International Guidelines now recommend MRI and Ultrasound in the routine management of Crohn's disease patients...
December 9, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27939180/long-term-morbidity-after-staging-laparotomy-for-hodgkin-s-lymphoma
#11
Inna Lobeck, Beth Rymeski, Karen Burns, Rajaram Nagarajan, Judy Correll, Debra Kent, Roshni Dasgupta
BACKGROUND: A large cohort of Hodgkin's lymphoma (HL) survivors exist. With patients transitioning from pediatric to adult care, practitioners should be aware of potential complications. The aim of this study was to describe the long-term complications of patients who had staging laparotomy for the treatment of HL. METHODS: After institutional review board approval, a retrospective review of hospital records at our institution was performed. Data extracted included demographics, treatment course and long-term postoperative complications...
December 2, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27920612/long-term-clinical-toxicity-of-radiation-therapy-in-prostate-cancer-patients-with-inflammatory-bowel-disease
#12
Matthew M Gestaut, Gregory P Swanson
AIM: The study's aim was to examine the clinical impact of radiation therapy (RT) on GI toxicity in Inflammatory Bowel Disease (IBD) patients. BACKGROUND: IBD has long been considered a risk factor for increased bowel toxicity from RT; however, minimal evidence exists on patients with prostate cancer (PC) and IBD. MATERIALS AND METHODS: The tumor registry was queried for patients with IBD and PC from the years 1990-2013. A retrospective review was conducted for patients who received RT...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27920469/role-of-ultrasound-in-colorectal-diseases
#13
REVIEW
Renáta Bor, Anna Fábián, Zoltán Szepes
Ultrasound is an undervalued non-invasive examination in the diagnosis of colonic diseases. It has been replaced by the considerably more expensive magnetic resonance imaging and computed tomography, despite the fact that, as first examination, it can usefully supplement the diagnostic process. Transabdominal ultrasound can provide quick information about bowel status and help in the choice of adequate further examinations and treatment. Ultrasonography, as a screening imaging modality in asymptomatic patients can identify several colonic diseases such as diverticulosis, inflammatory bowel disease or cancer...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27895640/%C3%AF-3-polyunsaturated-fatty-acids-as-immunomodulators-in-colorectal-cancer-new-potential-role-in-adjuvant-therapies
#14
REVIEW
Stefania Miccadei, Roberta Masella, Anna Maria Mileo, Sandra Gessani
Diet composition may affect the onset and progression of chronic degenerative diseases, including cancer, whose pathogenesis relies on inflammatory processes. Growing evidence indicates that diet and its components critically contribute to human health, affecting the immune system, secretion of adipokines, and metabolic pathways. Colorectal cancer (CRC) is one of the leading causes of death worldwide. Antineoplastic drugs are widely used for CRC treatment, but drug resistance and/or off-target toxicity limit their efficacy...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27856365/use-of-intestinal-ultrasound-to-monitor-crohn-s-disease-activity
#15
Torsten Kucharzik, Bianca M Wittig, Ulf Helwig, Norbert Börner, Alexander Rössler, Stefan Rath, Christian Maaser
BACKGROUND & AIMS: We performed a multicenter study to determine whether transabdominal bowel wall ultrasonography, a noninvasive procedure that does not require radiation, can be used to monitor progression of Crohn's disease (CD). METHODS: We performed a 12-month prospective, noninterventional study at 47 sites in Germany, from December 2010 through September 2014. Our study included 234 adult patients with CD who experienced a flare, defined as Harvey-Bradshaw index score of ≥7...
November 14, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27832710/radiation-exposure-in-patients-with-inflammatory-bowel-disease-and-irritable-bowel-syndrome-in-the-years-2001-2011
#16
Hanna Englund, Katarina Lidén K, Torbjörn Lind, Torbjörn Sundström, Pontus Karling
OBJECTIVES: To compare cumulative ionizing radiation in patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) for the years 2001-2011. To study how radiation exposure change over time in patients with newly diagnosed IBD and factors associated with radiation exposure. MATERIAL AND METHODS: All radiological investigations performed between 1 January 2001 and 31 December 2011 were retrospectively recorded in patients with Crohn's disease (CD) (n = 103), ulcerative colitis (UC) (n = 304) and IBS (n = 149)...
March 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27826994/diagnostic-efficacy-of-single-pass-abdominal-multidetector-row-ct-prospective-evaluation-of-a-low-dose-protocol
#17
Luigi Camera, Immacolata Liccardo, Federica Romano, Raffaele Liuzzi, Antonio Rispo, Massimo Imbriaco, Anna Testa, Gaetano Luglio, Simona De Fronzo, Fabiana Castiglione, Luigi Bucci, Arturo Brunetti
OBJECTIVE: To evaluate the diagnostic efficacy of single-pass contrast-enhanced multidetector CT (CE-MDCT) performed with a low-radiation high-contrast (LR-HC) dose protocol in selected patients with non-traumatic acute bowel disease. METHODS: 65 (32 males, 33 females; aged 20-67 years) consecutive patients with non-traumatic acute bowel disease underwent single-pass CE-MDCT performed 70-100 s after i.v. bolus injection of a non-ionic iodinated contrast medium (CM) (370 mgI ml(-1))...
February 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/27824535/update-on-the-management-of-intestinal-failure
#18
REVIEW
Shishira Bharadwaj, Parul Tandon, John M Rivas, Anne Furman, Lisa Moccia, Ashley Ratliff, Abdullah Shatnawei, Ezra Steiger, Donald F Kirby
Intestinal failure is a serious complication of conditions such as inflammatory bowel disease, mesenteric ischemia, and radiation enteritis--and of extensive bowel resection performed because of these diseases. Imbalances of fluids and electrolytes and poor nutritional status manifest as chronic diarrhea or increased ostomy output. Prompt referral to a center specializing in intestinal rehabilitation is key to achieving nutritional homeostasis and, in some cases, can help the patient return to oral food intake...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27816300/racial-variation-in-patient-reported-outcomes-following-treatment-for-localized-prostate-cancer-results-from-the-ceasar-study
#19
Mark D Tyson, JoAnn Alvarez, Tatsuki Koyama, Karen E Hoffman, Matthew J Resnick, Xiao-Cheng Wu, Matthew R Cooperberg, Michael Goodman, Sheldon Greenfield, Ann S Hamilton, Mia Hashibe, Lisa E Paddock, Antoinette Stroup, Vivien W Chen, David F Penson, Daniel A Barocas
BACKGROUND: Relatively little is known about the relationship between race/ethnicity and patient-reported outcomes after contemporary treatments for localized prostate cancer. OBJECTIVE: To test the hypothesis that treatment-related changes in urinary, bowel, sexual, and hormonal function vary by race/ethnicity. DESIGN, SETTING, AND PARTICIPANTS: The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study is a prospective, population-based, observational study that enrolled 3708 men diagnosed with localized prostate cancer in 2011-2012...
November 2, 2016: European Urology
https://www.readbyqxmd.com/read/27768579/the-prevalence-of-ostomy-related-complications-1-year-after-ostomy-surgery-a-prospective-descriptive-clinical-study
#20
Eva Carlsson, Jeanette Fingren, Anne-Marie Hallén, Charlotta Petersén, Elisabet Lindholm
Despite advancements in the creation and care of stomas, ostomy and peristomal skin complications are common immediately following surgery as well as in the months and years thereafter. A prospective study to determine the prevalence of ostomy and peristomal skin complications and the influence of ostomy configuration on such complications was conducted 1 year after ostomy surgery among all patients at a university hospital in Sweden. All participants received regular (10 to 14 days post discharge, 6 weeks, 3 months, 6 months, and 1 year post surgery) ostomy follow-up care by a wound ostomy continence (WOC) nurse...
October 2016: Ostomy/wound Management
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