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Maria Aslam, Mobasher Ahmad, Fizza Mobasher
OBJECTIVES OF THE STUDY: The aim of the study was to compare the efficacy and tolerability of different classes of antihypertensive drugs in diabetic and nondiabetic patients (NDPs) with essential hypertension. MATERIAL AND METHODS: The study was conducted in Mayo Hospital, Punjab Institute of Cardiology, and National Defence Hospital, Lahore, Pakistan, on 200 hypertensive patients with diabetes and 230 hypertensive patients without (Three hospitals) diabetes. Both male and female patients of age between 30 and 80 years with systolic blood pressure (SBP) above 130 mmHg and diastolic blood pressure (DBP) above 80 mmHg were enrolled in the study...
January 2017: Journal of Pharmacy & Bioallied Sciences
Jing Lu, Wen-Hui Zhou, Liang Ren, Yuan-Zhen Zhang
Preeclampsia is a pregnancy disorder with sudden onset of maternal hypertension and proteinuria, which is characterized by defective cytotrophoblast invasion, increased apoptosis in cytotrophoblast, and diminished syncytial differentiation. In this study, samples from 11 mild preeclamptic patients, 18 severe preeclamptic patients, and 21 normal pregnant women were collected. The expression level of CXCL12 and its two receptors (CXCR4 and CXCR7) in these samples and their relationship with apoptosis were investigated...
February 2016: Experimental and Molecular Pathology
Ismaila Raji, Pierre Mugabo, Kenechukwu Obikeze
BACKGROUND: Tulbaghia violacea Harv. (Alliaceae) is used to treat various ailments, including hypertension (HTN) in South Africa. This study aims to evaluate the contributions of muscarinic receptors and changes in plasma aldosterone levels to its anti-hypertensive effect. METHODS: In the acute experiments, methanol leaf extracts (MLE) of T. violacea (30-120 mg/kg), muscarine (0.16 -10 μg/kg), and atropine (0.02 - 20.48 mg/kg), and/or the vehicle (dimethylsulfoxide (DMSO) and normal saline (NS)) were respectively and randomly administered intravenously in a group of spontaneously hypertensive (SHR) weighing 300 to 350 g and aged less than 5 months...
2013: BMC Complementary and Alternative Medicine
No abstract text is available yet for this article.
May 1965: Klinicheskaia Meditsina
No abstract text is available yet for this article.
January 15, 1961: Minerva Chirurgica
E Agabiti Rosei
No abstract text is available yet for this article.
2003: Blood Pressure
K O Haustein
Diseases of the cardiovascular system such as coronary heart disease, hypertesion, peripheral occlusive arterial disease, and their final or lethal states (acute myocardial infarction, apoplectic stroke, congestive heart failure) occur 3 to 4 times more frequently than lung cancer in heavy smokers. Cigarette smoking impairs the courses of the microcirculation by an elevated viscosity of the blood or plasma, by a diminished deformability of the red blood cells, by elevated white cell counts, by activation of several blood clotting factors such as factor XIII and von Willebrand factor, by an elevated aggregability of the blood platelets, and by an increased uptake of fibrinogen into the endothelium of the blood vessels...
1999: Wiener Medizinische Wochenschrift
A La Manna, T Spagnoletti, G Galizia, L Ponticiello, R De Luca
The aim of this work is the recognition, if any, of connection of arterial hypertension and some risk factors in obese children. In the schools of two little towns of our Region 114 subjects were selected, 57 males and 57 females, aged between 6, 5 and 15 years, with a body weight superior to that corresponding to the 95th percentils in the same age class. The blood pressure values were related to age and height and it was decided to consider hypertese those children whose pressure values corresponded to 95th and 97, 5th, respectively in the same class of age and height...
March 15, 1982: Bollettino Della Società Italiana di Biologia Sperimentale
(no author information available yet)
No abstract text is available yet for this article.
January 1971: Health Bulletin
G Borello, P Dessy, P Russo, G Accatino, A Bellone, A Brocchi, A Rappelli, A Viara
The main coronary risk factors were estimated in a series of 287 myocardial infarct patients admitted to a coronary unit. Particular attention is drawn to smoking, arterial hypertesion, diabetes and hypercholesterolaemia in this respect. 24 cases in patients under 40 yr where cigarette smoking was by far the most important factor are examined more closely.
April 4, 1975: Minerva Medica
S N Orlov, N I Pokudin, Iu V Postnov
As compared to fatty tissue cells of animals with normal pressure, those of SHR rats were found to be characterized by a higher lipolytic response and a larger increase in the cAMP content on exposure to the effect of ACTH. As compared to the controls, adrenalectomized SHR rats had an increased basal cAMP content and an increased lipolytic response of the adipocytes following adrenaline administration. In inhibition of phosphodiesterase in the fatty cells of adrenalectomized rats with normal pressure, the cAMP content grew by 20% as compared to that in SHR rats subjected to the operation...
September 1978: Kardiologiia
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