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https://www.readbyqxmd.com/read/28529874/shared-and-disorder-specific-task-positive-and-default-mode-network-dysfunctions-during-sustained-attention-in-paediatric-attention-deficit-hyperactivity-disorder-and-obsessive-compulsive-disorder
#1
Luke J Norman, Christina O Carlisi, Anastasia Christakou, Ana Cubillo, Clodagh M Murphy, Kaylita Chantiluke, Andrew Simmons, Vincent Giampietro, Michael Brammer, David Mataix-Cols, Katya Rubia
Patients with Attention-Deficit/Hyperactivity Disorder (ADHD) and obsessive/compulsive disorder (OCD) share problems with sustained attention, and are proposed to share deficits in switching between default mode and task positive networks. The aim of this study was to investigate shared and disorder-specific brain activation abnormalities during sustained attention in the two disorders. Twenty boys with ADHD, 20 boys with OCD and 20 age-matched healthy controls aged between 12 and 18 years completed a functional magnetic resonance imaging (fMRI) version of a parametrically modulated sustained attention task with a progressively increasing sustained attention load...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28529361/prevalence-and-correlates-of-obsessive-compulsive-disorder-and-subthreshold-obsessive-compulsive-disorder-among-college-students-in-kerala-india
#2
T S Jaisoorya, Y C Janardhan Reddy, B Sivasankaran Nair, Anjana Rani, Priya G Menon, M Revamma, C R Jeevan, K S Radhakrishnan, Vineetha Jose, K Thennarasu
CONTEXT: There are scarce data on the prevalence of adult obsessive-compulsive disorder (OCD) in India. AIMS: The aim was to study the point prevalence of OCD and subthreshold OCD and its psychosocial correlates among college students in the district of Ernakulam, Kerala, India. SETTINGS AND DESIGN: A cross-sectional survey of 5784 students of the age range of 18-25 years from 58 colleges was conducted. MATERIALS AND METHODS: Students were self-administered the OCD subsection of the Clinical Interview Schedule-Revised, the Composite International Diagnostic Interview for obsessive-compulsive symptoms (OCSs), and other relevant instruments to identify OCD, subthreshold OCD, and related clinical measures...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28528596/face-and-object-perception-in-body-dysmorphic-disorder-versus-obsessive-compulsive-disorder-the-mooney-faces-task
#3
Wei Lin Toh, David J Castle, Susan L Rossell
OBJECTIVES: Body dysmorphic disorder (BDD) is characterized by repetitive behaviors and/or mental acts occurring in response to preoccupations with perceived defects or flaws in physical appearance. There are some similarities, but also important differences, between BDD and obsessive-compulsive disorder (OCD), not just in terms of core clinical symptoms, but possibly in the domain of perception. This study compared the nature and extent of perceptual anomalies in BDD versus OCD and health controls (HC), using a modified Mooney task...
May 22, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28528243/overvalued-ideation-in-adolescents-with-obsessive-compulsive-disorder
#4
Tania Borda, Fugen Neziroglu, William Taboas, Dean McKay, Leah Frenkiel
In Obsessive Compulsive Disorder (OCD), overvalued ideas (OVI) are considered poor prognostic indicators in adults. To date, OVI has not been studied in an adolescent population with OCD, nor has it been examined in relation to obsessive-compulsive beliefs. To investigate the relationship between OVI and specific cognitions, fifty-five adolescents with OCD (35 male; 20 female; age range 13-17 years; M=14.05 years, SD=1.75 years) participated. It was predicted that OVI would be associated with symptom severity and would moderate obsessive-compulsive beliefs and functional disability...
May 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28523977/the-application-of-deep-brain-stimulation-in-the-treatment-of-psychiatric-disorders
#5
Ilse Graat, Martijn Figee, Damiaan Denys
Deep brain stimulation (DBS) is a last-resort treatment for neurological and psychiatric disorders that are refractory to standard treatment. Over the last decades, the progress of DBS in psychiatry has been slower than in neurology, in part owing to the heterogenic symptomatology and complex neuroanatomy of psychiatric disorders. However, for obsessive-compulsive disorder (OCD) DBS is now an accepted treatment. This study first reviews clinical outcomes and mechanisms of DBS for OCD, and then discusses these results in an overview of current and future psychiatric applications, including DBS for mood disorders, Tourette's syndrome, addiction, anorexia nervosa, autism, schizophrenia, and anxiety disorders...
April 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28517947/intolerance-of-uncertainty-predicts-increased-striatal-volume
#6
M Justin Kim, Jin Shin, James M Taylor, Alison M Mattek, Samantha J Chavez, Paul J Whalen
Oversensitivity to uncertain future threat is usefully conceptualized as intolerance of uncertainty (IU). Neuroimaging studies of IU to date have largely focused on its relationship with brain function, but few studies have documented the association between IU and the quantitative properties of brain structure. Here, we examined potential gray and white-matter brain structural correlates of IU from 61 healthy participants. Voxel-based morphometric analysis highlighted a robust positive correlation between IU and striatal volume, particularly the putamen...
May 18, 2017: Emotion
https://www.readbyqxmd.com/read/28515196/cost-effectiveness-of-therapist-guided-internet-delivered-cognitive-behaviour-therapy-for-paediatric-obsessive-compulsive-disorder-results-from-a-randomised-controlled-trial
#7
Fabian Lenhard, Richard Ssegonja, Erik Andersson, Inna Feldman, Christian Rück, David Mataix-Cols, Eva Serlachius
OBJECTIVES: To evaluate the cost-effectiveness of a therapist-guided internet-delivered cognitive behaviour therapy (ICBT) intervention for adolescents with obsessive-compulsive disorder (OCD) compared with untreated patients on a waitlist. DESIGN: Single-blinded randomised controlled trial. SETTING: A research clinic within the regular child and adolescent mental health service in Stockholm, Sweden. PARTICIPANTS: Sixty-seven adolescents (12-17 years) with a Diagnostic and Statistical Manual of Mental Disorders Fifth Edition diagnosis of OCD...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28512441/mapping-the-paths-from-styles-of-anger-experience-and-expression-to-obsessive-compulsive-symptoms-the-moderating-roles-of-family-cohesion-and-adaptability
#8
Liang Liu, Cuilian Liu, Xudong Zhao
Previous research has shown strong connections of anger experience and expression with obsessive-compulsive (OC) symptoms. Additionally, studies have demonstrated links between family environment variables and obsessive-compulsive disorder (OCD). Our study aims to integrate the perspectives from these two literatures by exploring the moderating roles of family cohesion and family adaptability in the relationship between anger proneness and suppression and OCD symptoms. A total of 2008 college students were recruited from a comprehensive university in Shanghai, China between February and May 2016...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28509714/preventing-occupational-skin-disease-a-review-of-training-programs
#9
Bethany Zack, Victoria H Arrandale, D Linn Holness
Occupational contact dermatitis (OCD) is a common occupational disease that impacts a variety of worker groups. Skin protection and disease prevention training programs have shown promise for improving prevention practices and reducing the incidence of OCD. This review details the features of training programs for primary prevention of OCD and identifies gaps in the literature. Twelve studies were identified for in-depth review: many studies included wet workers employed in health care, hairdressing, cleaning, and food preparation; 1 program featured manufacturing workers...
May 2017: Dermatitis
https://www.readbyqxmd.com/read/28507136/ocd-candidate-gene-slc1a1-eaat3-impacts-basal-ganglia-mediated-activity-and-stereotypic-behavior
#10
Isaac D Zike, Muhammad O Chohan, Jared M Kopelman, Emily N Krasnow, Daniel Flicker, Katherine M Nautiyal, Michael Bubser, Christoph Kellendonk, Carrie K Jones, Gregg Stanwood, Kenji Fransis Tanaka, Holly Moore, Susanne E Ahmari, Jeremy Veenstra-VanderWeele
Obsessive-compulsive disorder (OCD) is a chronic, disabling condition with inadequate treatment options that leave most patients with substantial residual symptoms. Structural, neurochemical, and behavioral findings point to a significant role for basal ganglia circuits and for the glutamate system in OCD. Genetic linkage and association studies in OCD point to SLC1A1, which encodes the neuronal glutamate/aspartate/cysteine transporter excitatory amino acid transporter 3 (EAAT3)/excitatory amino acid transporter 1 (EAAC1)...
May 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28505489/anxiety-sensitivity-as-a-predictor-of-outcome-in-the-treatment-of-obsessive-compulsive-disorder
#11
Shannon M Blakey, Jonathan S Abramowitz, Lillian Reuman, Rachel C Leonard, Bradley C Riemann
BACKGROUND AND OBJECTIVES: To address the fact that not all individuals who receive cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD) exhibit complete symptom reduction, research has examined factors that predict outcome; however, no studies have examined anxiety sensitivity (AS) as a predictor of outcome of CBT for OCD. AS refers to the fear of anxious arousal that results from mistaken beliefs about the dangerousness of anxiety-related body sensations. It is important to understand whether AS influences OCD treatment outcome, considering that (a) some obsessions directly relate to AS, and (b) OCD patients with high AS may be reluctant to engage in anxiety-provoking components of CBT for OCD...
May 6, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28504027/epidemiology-and-comorbidity-of-obsessive-compulsive-disorder-in-late-adolescence-a-cross-sectional-study-in-senior-high-schools-in-greece
#12
Spyridon Politis, Konstantina Magklara, Petros Petrikis, Grigorios Michalis, Gregoris Simos, Petros Skapinakis
OBJECTIVE: The aim of this study was to examine the epidemiology, comorbidity and use of health services of obsessive-compulsive disorder (OCD) and subclinical obsessive-compulsive symptoms in late adolescence. METHODS: A total of 2427 adolescents attending senior high schools in Greece were selected for a detailed psychiatric interview using the revised clinical interview schedule (CIS-R). Use of alcohol, nicotine and cannabis, and several socio-demographic and socio-economic variables were also assessed...
May 15, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28500953/induced-not-just-right-and-incompleteness-experiences-in-ocd-patients-and-non-clinical-individuals-an-in%C3%A2-vivo-study
#13
Gertrudis Fornés-Romero, Amparo Belloch
No abstract text is available yet for this article.
May 5, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28499570/the-obsessive-compulsive-inventory-child-version-oci-cv-further-evidence-on-confirmatory-factor-analytic-structure-incremental-and-criterion-validity-in-italian-community-children-and-adolescents
#14
Andrea Pozza, Barbara Barcaccia, Davide Dèttore
Obsessive Compulsive Inventory-Child Version (OCI-CV) assesses six dimensions of OCD symptoms in childhood and adolescence. The current study used confirmatory methods to assess factor structure and reliability of the Italian OCI-CV in community children and adolescents. 1408 community children and adolescents completed the OCI-CV and a subgroup (n=855) completed measures of other anxiety and depression symptoms. A six correlated factor structure showed good fit. Reliability was excellent for total OCI-CV and for the other scales ranged from good to acceptable...
June 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/28498087/an-expert-opinion-on-pandas-pans-highlights-and-controversies
#15
Francesca Chiarello, Silvia Spitoni, Eric Hollander, Marco Matucci Cerinic, Stefano Pallanti
OBJECTIVES: 'Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections' (PANDAS) identified a unique subgroup of patients with abrupt onset of obsessive compulsive disorder (OCD) symptoms clinically related to Streptococcus infection and accompanied by neuropsychological and motor symptoms. After almost 20 years, PANDAS has not been accepted as distinct disorder and new criteria for paediatric acute-onset neuropsychiatric syndrome (PANS) have been replaced it, highlighting the fact that several agents rather than only Streptococcus might be involved...
February 13, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28496499/psychiatric-comorbidities-and-environmental-triggers-in-patients-with-chronic-daily-headache-a-lifestyle-study
#16
Fakhrudin Faizi, Abbas Tavallaee, Aboulfazl Rahimi, Masoud Saghafinia
Objective: Patients with chronic daily headache (CDH) suffer from several significant psychiatric comorbidities and have unhealthy lifestyle. We aimed at studying psychiatric comorbidities, environmental triggers, lifestyle factors, and intensity of CDH in patients referred by the department of neurology from 2011 to 2014. Method: Through medical and psychiatric interviews and using 0 to 10 visual analogue scale (VAS), we assessed patients with CDH, using a checklist, to elicit psychiatric comorbidities, intensity of CDH, environmental factors, and lifestyle derangement...
January 2017: Iranian Journal of Psychiatry
https://www.readbyqxmd.com/read/28496402/cortico-striatal-thalamic-loop-circuits-of-the-orbitofrontal-cortex-promising-therapeutic-targets-in-psychiatric-illness
#17
REVIEW
Peter Fettes, Laura Schulze, Jonathan Downar
Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex human behaviors such as evaluation, affect regulation and reward-based decision-making. Importantly, the medial and lateral OFC (mOFC and lOFC) circuits have functionally and anatomically distinct connectivity profiles which differentially contribute to the various aspects of goal-directed behavior. OFC corticostriatal circuits have been consistently implicated across a wide range of psychiatric disorders, including major depressive disorder (MDD), obsessive compulsive disorder (OCD), and substance use disorders (SUDs)...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28487007/unpacking-the-role-of-self-reported-compulsivity-and-impulsivity-in-obsessive-compulsive-disorder
#18
Luisa Prochazkova, Linden Parkes, Andrew Dawson, George Youssef, Gabriela M Ferreira, Valentina Lorenzetti, Rebecca A Segrave, Leonardo F Fontenelle, Murat Yücel
OBJECTIVE: We aimed to determine whether individuals with obsessive-compulsive disorder (OCD) and demographically matched healthy individuals can be clustered into distinct clinical subtypes based on dimensional measures of their self-reported compulsivity (OBQ-44 and IUS-12) and impulsivity (UPPS-P). METHODS: Participants (n=217) were 103 patients with a clinical diagnosis of OCD; 79 individuals from the community who were "OCD-likely" according to self-report (Obsessive-Compulsive Inventory-Revised scores equal or greater than 21); and 35 healthy controls...
May 10, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28485008/l-carnosine-as-an-adjuvant-to-fluvoxamine-in-treatment-of-obsessive-compulsive-disorder-a-randomized-double-blind-study
#19
Somaye Arabzadeh, Maryam Shahhossenie, Bita Mesgarpour, Farzin Rezaei, Mohammad Reza Shalbafan, Zahra Ghiasi, Shahin Akhondzadeh
BACKGROUND: Dysregulation of glutamate is implicated in the pathogenesis of obsessive-compulsive disorder (OCD). Consistently, glutamate-modulating agents, such as riluzole and memantine have been used in OCD treatment. Previous research has identified some neuroprotective role for L-carnosine potentially via its modulatory effect on glutamate. Here, we assessed the efficacy of L-carnosine as adjuvant to fluvoxamine in OCD treatment. METHODS: Forty-four patients diagnosed with moderate to severe OCD were recruited in a randomized double-blind trial...
May 8, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28483079/factor-analysis-of-y-bocs-checklist-and-severity-scale-among-patients-with-schizophrenia
#20
Sandeep Grover, Devakshi Dua, Subho Chakrabarti, Ajit Avasthi
AIM: To carry out factor analysis of YBOCS checklist and YBOCS severity scale among patients with schizophrenia. METHODOLOGY: 181 patients of schizophrenia were assessed on the Yale Brown Obsessive Compulsive Symptom (YBOCS) checklist, YBOCS severity scale and, positive and negative syndrome scale (PANSS). RESULTS: About one fourth (28.18%) of the patients fulfilled the diagnosis of current OCD and 29.83% of patients fulfilled the lifetime diagnosis of OCD...
April 2017: Asian Journal of Psychiatry
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