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https://www.readbyqxmd.com/read/28716021/missed-diagnoses-in-african-americans-with-obsessive-compulsive-disorder-the-structured-clinical-interview-for-dsm-iv-axis-i-disorders-scid-i
#1
Gregory S Chasson, Monnica T Williams, Darlene M Davis, Jessica Y Combs
BACKGROUND: Research on the utility of structured interviews in assessing OCD is scarce, and even more so, in its use for OCD in African Americans. The purpose of this study was to examine the utility of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) in detecting OCD in African Americans when used by well-trained, culturally competent clinicians. METHODS: Seventy-four African American adults with OCD were assessed with the SCID-I and additional measures of OCD...
July 17, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28715850/how-willing-are-you-willingness-as-a-predictor-of-change-during-treatment-of-adults-with-obsessive-compulsive-disorder
#2
Adam M Reid, Lauryn E Garner, Nathaniel Van Kirk, Christina Gironda, Jason W Krompinger, Brian P Brennan, Brittany M Mathes, Sadie Cole Monaghan, Eric D Tifft, Marie-Christine André, Jordan Cattie, Jesse M Crosby, Jason A Elias
OBJECTIVE: Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explore whether willingness to experience unpleasant thoughts, emotions, and bodily sensations during ERP was associated with improved treatment response. METHODS: Two hundred eighty-eight adults with OCD receiving residential ERP provided self-rated willingness and other exposure-related variables during each daily coached ERP session...
July 17, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28711583/incidence-of-symptomatic-osteochondritis-dissecans-lesions-of-the-knee-a-population-based-study-in-olmsted-county
#3
Ayoosh Pareek, Thomas L Sanders, Isabella T Wu, Dirk R Larson, Daniel Bf Saris, Aaron J Krych
OBJECTIVE: To (1) define the population-based incidence of OCD lesions of the knee using the population of Olmsted County, (2) examine trends over time, and (3) evaluate changes in the rate of surgical management. METHOD: The study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. The complete medical records were reviewed to confirm diagnosis and to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population...
July 12, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28711111/to-do-or-not-to-do-task-control-deficit-in-obsessive-compulsive-disorder
#4
Eyal Kalanthroff, Avishai Henik, Helen Blair Simpson, Doron Todder, Gideon E Anholt
Task control is an executive control mechanism that facilitates goal-directed task selection by suppressing irrelevant automatic "stimulus-driven" behaviors. In the current study, we test the hypothesis that less efficient task control in individuals diagnosed with obsessive-compulsive disorder (OCD) is associated with OCD symptoms, and specifically, with the inability to inhibit unwanted behaviors in OCD. Thirty-five healthy controls, 30 participants with OCD, and 26 participants with generalized anxiety disorder (GAD) completed the object-interference (OI) task to measure task control, the stop-signal task to measure response inhibition, and the arrow-flanker task to evaluate executive abilities not contingent upon task control...
September 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28710918/intolerance-of-uncertainty-in-eating-disorders-an-update-on-the-field
#5
REVIEW
Alice Kesby, Sarah Maguire, Rachel Brownlow, Jessica R Grisham
Pathological fear and anxiety regarding food, eating, weight and body shape are at the core of eating disorder (ED) psychopathology. To manage anxiety, patients develop complicated repertoires of ritualistic and repetitive behaviours, which can lead to total functional impairment. Yet the cognitive processes underlying anxiety, fear, and anxiety-driven behaviours in EDs remain poorly understood. Intolerance of Uncertainty (IU) is defined as a tendency to react negatively on an emotional, cognitive, and behavioural level to uncertain situations and events...
July 5, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28707590/combining-drug-and-psychological-treatments-for-obsessive-compulsive-disorder-what-is-the-evidence-when-and-for-whom
#6
Umberto Albert, Gabriele Di Salvo, Francesca Solia, Gianluca Rosso, Giuseppe Maina
BACKGROUND: serotonin reuptake inhibitors (SRIs) and cognitive-behavioral psychotherapy (CBT) are first-line treatments for obsessive-compulsive disorder (OCD). Since response is often inadequate, in recent years researchers investigated whether combining CBT and SRIs, either ab initio or sequentially, results in a greater reduction of obsessive-compulsive symptoms. OBJECTIVE: the aims of the present paper are to assess if combination treatment seems adding benefits as compared to either monotherapy alone and if sequential strategies may be effective in converting partial or non responders to a first-line treatment into responders...
July 12, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28707502/appraisal-of-the-psychiatric-diagnostic-screening-questionnaire-in-a-perinatal-cohort-the-apron-study
#7
Brenda Leung, Nicole Letourneau, Katherine Bright, Gerald F Giesbrecht, Henry Ntanda, Lisa Gagnon
BACKGROUND: Depression and anxiety are routinely screened as part of perinatal care. However, other Axis 1 disorders and specific anxiety disorders are less likely to be screened or assessed as part of obstetric care. The objective of this study was to determine whether the Psychiatric Diagnostic Screening Questionnaire (PDSQ) is a potentially useful tool to screen for psychiatric conditions in pregnant and postpartum women in a community setting. METHODS: We compared the prevalence of DSM Axis I disorders obtained on the PDSQ with: (1) the prevalence of these disorders reported in previous studies of pregnant and postpartum women, and (2) scores obtained on the Edinburgh Postpartum Depression Scale (EPDS) and the Symptom Checklist-90-Revised (SCL-90R) anxiety scale...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28706836/arthroscopic-treatment-of-capitellum-osteochondritis-dissecans-with-micronized-allogeneic-cartilage-scaffold
#8
Paul E Caldwell, Brett Auerbach, Sara E Pearson
Osteochondritis dissecans (OCD) of the capitellum is a common disorder that causes pain and functional limitation in the adolescent elbow. Although conservative management is the first line of treatment, surgical intervention is usually recommended for patients with persistent mechanical symptoms, loose bodies, or unstable lesions. Elbow arthroscopy has become the gold standard to evaluate and treat symptomatic OCD lesions. Arthroscopic debridement and bone marrow stimulation have been shown to yield good short-term results...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28705679/the-effects-of-cognitive-reappraisal-on-conditioned-disgust-in-contamination-based-ocd-an-analogue-study
#9
Bunmi O Olatunji, Hannah Berg, Rebecca C Cox, Amber Billingsley
Experimental research has shown that conditioned disgust is resistant to extinction, which may account for the slower habituation to disgust relative to fear in contamination-based obsessive-compulsive disorder (OCD). However, few studies have examined the efficacy of interventions that may attenuate conditioned disgust responses. Studies of cognitive reappraisal have demonstrated that reinterpreting a stimulus can alter emotional responding. This technique is based on cognitive theories which suggest that anxiety disorders arise from biased cognitions; therefore, changing a person's thoughts will elicit durable changes in emotional responses...
July 1, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28705162/the-effect-of-autologous-adipose-derived-mesenchymal-stem-cell-therapy-in-the-treatment-of-a-large-osteochondral-defect-of-the-knee-following-unsuccessful-surgical-intervention-of-osteochondritis-dissecans-a-case-study
#10
Julien Freitag, Kiran Shah, James Wickham, Richard Boyd, Abi Tenen
BACKGROUND: A prospective analysis of the effect of autologous adipose derived mesenchymal stem cell (MSC) therapy in the treatment of an osteochondral defect of the knee with early progressive osteoarthritis following unsuccessful surgical intervention of osteochondritis dissecans (OCD). CASE PRESENTATION: After failed conventional management of OCD a patient undergoes intra-articular MSC therapy. Patient outcome measures included the Numeric Pain Rating Scale (NPRS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee Injury and Osteoarthritis Outcome Score (KOOS)...
July 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28705096/autism-spectrum-disorders-in-adult-outpatients-with-obsessive-compulsive-disorder-in-the-uk
#11
Maheshi Wikramanayake, William Mandy, Sonia Shahper, Sukhwinder Kaur, Sangeetha Kolli, Selma Osman, Jemma Reid, Kiri Jefferies Sewell, Naomi Fineberg
BACKGROUND: Patients with obsessive compulsive disorder (OCD) frequently show traits of autism spectrum disorders (ASD). This is one of the first studies to explore the clinical impact of the overlap between OCD and ASD as a categorical diagnosis. METHODS: A cross-sectional survey in 73 adult outpatients with DSM-IV OCD. Autistic traits were measured using the Autism-Spectrum Quotient (AQ). A clinical estimate ASD diagnosis was made by interview using DSM-IV-TR criteria...
July 14, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28698817/the-fabrication-of-biomimetic-biphasic-can-pac-hydrogel-with-a-seamless-interfacial-layer-applied-in-osteochondral-defect-repair
#12
Jinfeng Liao, Taoran Tian, Sirong Shi, Xueping Xie, Quanquan Ma, Guo Li, Yunfeng Lin
Cartilage tissue engineering based on biomimetic scaffolds has become a rapidly developing strategy for repairing cartilage defects. In this study, a biphasic CAN-PAC hydrogel for osteochondral defect (OCD) regeneration was fabricated based on the density difference between the two layers via a thermally reactive, rapid cross-linking method. The upper hydrogel was cross-linked by CSMA and NIPAm, and the lower hydrogel was composed of PECDA, AAm and PEGDA. The interface between the two layers was first grafted by the physical cross-linking of calcium gluconate and alginate, followed by the chemical cross-linking of the carbon-carbon double bonds in the other components...
2017: Bone Research
https://www.readbyqxmd.com/read/28697487/predictors-of-illness-anxiety-symptoms-in-patients-with-obsessive-compulsive-disorder
#13
Lillian Reuman, Ryan J Jacoby, Shannon M Blakey, Bradley C Riemann, Rachel C Leonard, Jonathan S Abramowitz
Illness anxiety and OCD symptoms appear to overlap in their presentation as well as in other conceptually important ways (e.g., dysfunctional cognitions). Little research, however, has directly examined these putative relationships. The present study examined the extent to which illness anxiety symptoms were associated with OCD symptom dimensions and relevant cognitive factors in a large treatment-seeking sample of patients with OCD. Patients completed a battery of self-report measures of OCD and health anxiety symptoms and related cognitive biases...
July 5, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28691955/children-with-obsessive-compulsive-symptomology-in-the-general-population-different-subtypes
#14
Josjan Zijlmans, Reshmi Marhe, Jan van der Ende, Frank C Verhulst, Arne Popma, Henning Tiemeier, Odile A van den Heuvel
OBJECTIVE: Obsessive-compulsive disorder (OCD) is a moderately prevalent neurodevelopmental disorder, and many children suffer from subclinical obsessive-compulsive (OC) symptoms. The disorder is heterogeneous and has high comorbidity rates. In early disease stages of psychiatric disorders, symptoms are typically hard to attribute exclusively to specific disorders. The authors investigated whether profiles of neuropsychiatric symptoms can be distinguished within a large population-based study of school-aged children (7-10 years) scoring high on OC symptoms...
July 6, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28691550/relationships-between-obsessive-compulsive-disorder-depression-and-functioning-before-and-after-exposure-and-response-prevention-therapy
#15
Sarosh J Motivala, Maria Arellano, Rebecca Greco, David Aiken, Nathan Hutchenson, Reza Tadayonnejad, Joseph O'Neill, Jamie D Feusner
OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with impaired functioning and depression. Our aim was to examine relationships between OCD symptoms, depression, and functioning before and after exposure and response prevention (ERP), a type of cognitive-behavioral therapy for OCD, specifically examining whether functioning, depression and other cognitive factors like rumination and worry acted as mediators. METHODS: Forty-four individuals with OCD were randomized to four weeks of intensive ERP treatment first (n = 23) or waitlist then treatment (n = 21)...
July 8, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28691545/association-of-the-functional-serotonin-transporter-haplotype-with-familial-form-of-obsessive-compulsive-disorder-in-iranian-patients
#16
Fatemeh Sadat Rashidi, Ehsan Ahmadipour, Sepideh Shiravand, Abolhassan Ahmadiani, Sareh Asadi, Jamal Shams
OBJECTIVE: Several polymorphisms have been reported in the 5-HTTLPR of the serotonin transporter gene (SLC6A4). Family-based evidences for the association of 5-HTTLPR polymorphisms with OCD were previously reported but results were controversial. The present study investigated the possible correlation of SLC6A4 polymorphisms (5-HTTLPR, rs25532, rs25531) in Iranian OCD patients considering gender, age of onset, family history of psychiatric disorders, obsessive and compulsive subtypes and severities...
July 10, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28690014/psychiatric-symptoms-in-myoclonus-dystonia-syndrome-are-just-concomitant-features-regardless-of-the-sgce-gene-mutation
#17
Ji-Young Kim, Woong-Woo Lee, Chae Won Shin, Han-Joon Kim, Sung-Sup Park, Sun Ju Chung, Jin Whan Cho, Ho-Sung Ryu, Tae Ok Son, Beomseok Jeon
INTRODUCTION: Among myoclonus-dystonia syndrome (MD) patients, psychiatric disorders including depression, anxiety, alcohol dependence, obsessive-compulsive disorder (OCD) and panic disorder have been frequently reported to be related with the epsilon-sarcoglycan gene (SGCE) mutation. However, the rate of psychiatric disorders has not been compared between MD patients with the SGCE mutation (SGCE (+)) and without the SGCE mutation (SGCE (-)). We analyzed the psychiatric data in both SGCE (+) and SGCE (-) MD patients to determine the association of the SGCE mutation with psychiatric disorders in MD...
June 23, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28688007/how-is-patella-height-modified-after-total-knee-arthroplasty
#18
Jean Louis Prudhon, Jacques H Caton, Thierry Aslanian, Régis Verdier
INTRODUCTION: Since the first measurement method of patella height in 1929 (Janssen), more than 16 methods have been described. Most of these measures are not suitable to measure patella height after total knee arthroplasty (TKA). One of us (JC) modified the original Caton Deschamps (oCD), index with a new relative index called modified Caton Deschamps (mCD) index, by using new landmarks. The purpose of this study was to determine how patella height is modified after TKA. MATERIAL AND METHOD: Sixty primary TKAs were consecutively prospectively enrolled...
July 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28687862/no-superior-surgical-treatment-for-secondary-osteochondral-defects-of-the-talus
#19
REVIEW
Kaj T A Lambers, Jari Dahmen, Mikel L Reilingh, Christiaan J A van Bergen, Sjoerd A S Stufkens, Gino M M J Kerkhoffs
PURPOSE: The purpose of this systematic review was to identify the most effective surgical treatment for talar osteochondral defects after failed primary surgery. METHODS: A literature search was conducted to find studies published from January 1996 till July 2016 using PubMed (MEDLINE), EMBASE, CDSR, DARE and CENTRAL. Two authors screened the search results separately and conducted quality assessment independently using the Newcastle-Ottawa scale. Weighted success rates were calculated...
July 7, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28687447/repetitive-transcranial-magnetic-stimulation-of-the-supplementary-motor-area-in-treatment-resistant-obsessive-compulsive-disorder-an-open-label-pilot-study
#20
Young-Ji Lee, Bon-Hoon Koo, Wan-Seok Seo, Hye-Geum Kim, Ji-Yean Kim, Eun-Jin Cheon
Obsessive-compulsive disorder (OCD) is a severely distressing disorder represented by obsessions and compulsions. A significant proportion of OCD patients fail to improve with conventional treatment methods. Repetitive transcranial magnetic stimulation (rTMS) has been proposed as an alternative for OCD treatment. Functional neuroimaging studies indicate that OCD is associated with increased activity in the supplementary motor area (SMA), a region that plays an important role in the pathophysiology of this disorder...
July 4, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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