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https://www.readbyqxmd.com/read/28724339/influence-of-cerebrovascular-reactivity-on-outcome-of-the-patients-with-%C3%A2-50-symptomatic-unilateral-middle-cerebral-artery-stenosis
#1
Weiqing Zhang, Yanwei Yin, Yingqian Zhang, Fen Yang, Wenqian Shi, Dawei Chen, Chen Song, Huiping Shi, Xuanzhu Zhao, Jin Shi
Cerebrovascular reactivity (CVR) reflects the vasodilatory reserve of cerebral resistance vessels, which is an important marker for assessing cerebrovascular disease. The present study is to investigate whether CVR impairment increases adverse long-term outcome risk of patients with ≥ 50% symptomatic unilateral middle cerebral artery (MCA) stenosis (ischemic stroke (IS) or transient ischemic attack (TIA)). Digital subtraction angiography (DSA) was used to assess the degree of stenosis, and perfusion CT and 5% CO2 inhalation were adopted to evaluate CVR...
July 20, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28722300/digital-subtraction-angiography-dynavision-in-pretreatment-planning-for-embolization-of-dural-arterio-venous-fistulas
#2
Alex Botsford, Jai Jai Shiva Shankar
BACKGROUND AND PURPOSE: We have found DSA-Dynavision with multiplanar reconstruction very helpful in understanding the complex anatomy and planning of treatment of carotico-cavernous fistulas. The purpose of our study was to examine whether using DSA-Dynavision in pretreatment planning results in better outcome after endovascular treatment of dural arterio-venous fistulas (dAVFs). METHODS: Patients with dAVF treated with endovascular embolization were retrospectively identified from our interventional neuroradiology database...
July 19, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28716984/the-risk-of-ischemic-events-increased-in-patients-with-asymptomatic-carotid-stenosis-with-decreased-cerebrovascular-reserve
#3
Shulan Liu, Jing Cai, Fugui Ge, Wei Yue
Identifying high-risk patients with asymptomatic carotid stenosis (ACS) is necessary regardless of whether intensive medical therapy or aggressive treatment is applied. In order to assess the relationship between cerebrovascular reserve (CVR) measured by perfusion CT with inhalation of CO2 and the risk of ischemic events in ACS, this long-term follow-up study was conducted. Forty-five patients with ACS who underwent the examination of CVR measured by perfusion CT with inhalation of CO2 were collected and followed-up for at least 5 years...
July 17, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28713522/the-effect-of-motivational-interviewing-based-intervention-using-self-determination-theory-on-promotion-of-physical-activity-among-women-in-reproductive-age-a-randomized-clinical-trial
#4
Seyed Saeed Mazloomy Mahmoodabad, Nooshin Rouhani Tonekaboni, Rabiollah Farmanbar, Hossein Fallahzadeh, Tahereh Kamalikhah
BACKGROUND: Physical activity (PA) prevents chronic diseases. Self-determination theory (SDT) provides a useful framework to understand the nature of motivational interviewing (MI). OBJECTIVE: This study aimed to determine the effect of MI-based intervention using SDT on the promotion of PA among women in reproductive age. METHODS: Seventy women in reproductive age were selected by clustering sampling method for this randomized controlled trial...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28705443/-impact-of-sickle-cell-trait-on-arterial-stiffness-in-african-subjects
#5
V Ouédraogo, R Soleti, I Signolet, M Diaw, M Hallab, A Samb, R Andriantsitohaina, A Ba, G Lefthériotis
Sickle cell trait (SCT) is the benign condition of sickle cell disease. Often asymptomatic, the carriers of the sickle cell trait have hemorheological disturbances with increased oxidative stress compared to healthy subjects. These disturbances can lead to structural and functional changes in large vessels. The aim of the study was to measure arterial stiffness, an independent marker of subclinical atherosclerosis, SCT carriers compared to sickle cell anemia (SCA) subjects. Nine SCT carriers aged 32±9 years (7 men) were compared to 14 SCA subjects aged 29±9 years (2 men) and 22 control subjects aged 34±9 years (11 men) recruited by the National blood transfusion center (CNTS) in Dakar (Senegal)...
February 2017: J Med Vasc
https://www.readbyqxmd.com/read/28704454/indocyanine-green-kinetics-with-near-infrared-spectroscopy-predicts-cerebral-hyperperfusion-syndrome-after-carotid-artery-stenting
#6
Ichiro Nakagawa, Hun Soo Park, Shohei Yokoyama, Shuichi Yamada, Yasushi Motoyama, Young Su Park, Takeshi Wada, Kimihiko Kichikawa, Hiroyuki Nakase
BACKGROUND: Cerebral hyperperfusion syndrome (HPS) is a potentially life-threatening complication following carotid artery stenting (CAS) and carotid endoarterectomy (CEA). Early prediction and treatment of patients at risk for HPS are required in patients undergoing CAS because HPS occurs significantly earlier after CAS than CEA. Near-infrared spectroscopy (NIRS) is often used for monitoring, and indocyanine green (ICG) kinetics by NIRS (ICG-NIRS) can detect reductions in cerebral perfusion in patients with acute stroke...
2017: PloS One
https://www.readbyqxmd.com/read/28687350/clinical-response-to-long-term-tenofovir-monotherapy-in-korean-chronic-hepatitis-b-patients
#7
Eun-Hyung Yoo, Hyun-Jung Cho
BACKGROUND: Tenofovir disoproxil fumarate (TDF) is a potent nucleotide analogue recommended as first-line monotherapy for chronic hepatitis B (CHB). We investigated the clinical response to TDF monotherapy in Korean CHB patients. METHODS: A total of 90 CHB patients [55 hepatitis B e antigen (HBeAg)-positive and 35 HBeAg-negative] who received TDF monotherapy for >2year, were enrolled. Quantitative hepatitis B surface antigen (qHBsAg) levels, serum alanine aminotransferase (ALT), HBeAg, anti-HBe and HBV DNA levels were measured during treatment...
July 4, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28680872/validity-and-reliability-of-the-questionnaire-for-assessing-women-s-reproductive-history-in-azar-cohort-study
#8
Mohammad Zakaria Pezeshki, Atefeh Shadman, Mahasti Alizadeh, Sevil Hakimi, Fariba Heidari
This study was done to evaluate the validity and reliability of women's reproductive history questionnaire which will be used in Azar Cohort study; a cohort that is conducted by Tabriz University of Medical Science in Shabestar county for identifying risk factors of no communicable diseases. Content and face validity were evaluated by ten experts in the field and quantified as content validity index (CVI) and content validity ratio (CVR). To assess the reliability, using test-retest approach, kappa statistic was calculated for categorical variables and intra-class correlation coefficient (ICC) was used for the quantitative items...
June 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28674599/the-effect-of-betaine-on-nitrate-and-cardiovascular-response-to-exercise
#9
J Luke Pryor, S Tony Wolf, Gary Sforzo, Tom Swensen
Betaine (BT) supplementation improves selected markers of physical performance, however, the mechanism(s) by which this change occurs remains largely unknown. Some speculate that BT may increase circulating nitrate concentrations, improving physical performance by augmentation of endothelial nitric oxide production. The purpose of this study was to investigate the effects of acute BT supplementation and exercise on plasma nitrate levels and related cardiovascular response (CVR). Placebo and BT trials were administered in a cross-over, randomized, double-blind, and counterbalanced fashion...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28654646/developing-and-validating-a-scale-to-measure-food-and-nutrition-literacy-fnlit-in-elementary-school-children-in-iran
#10
Aazam Doustmohammadian, Nasrin Omidvar, Nastaran Keshavarz-Mohammadi, Morteza Abdollahi, Maryam Amini, Hassan Eini-Zinab
BACKGROUND: Food and nutrition literacy is an emerging term which is increasingly used in policy and research. Though research in this area is growing, progression is limited by the lack of an accepted method to measure food and nutrition literacy. The aim of this study is to develop a valid and reliable questionnaire to assess food and nutrition literacy in elementary school children in the city of Tehran. METHODS: The study was conducted in three phases. To develop Food and Nutrition Literacy (FNLIT) questionnaire, a comprehensive literature review and a qualitative study were initially performed to identify food and nutrition literacy dimensions and its components...
2017: PloS One
https://www.readbyqxmd.com/read/28653259/a-medication-assessment-tool-to-evaluate-prescribers-adherence-to-evidence-based-guidelines-in-bipolar-disorder
#11
Dalal M Al-Taweel, Mohammad Alsuwaidan
Background The goal of evidence-based clinical practice has led to an increased interest in the development of tools to measure adherence to national guidelines in different diseases. This aids in detecting and measuring inappropriate prescribing to specific patient groups by using quality standards extracted from evidence-based guidelines, and ultimately provide the basis of consistent standardized prescribing. Objective To design and validate a medication assessment tool to assess prescribers' adherence to international guideline recommendations in the management of bipolar disorder (MATBD)...
June 26, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28648106/pressure-autoregulation-measurement-techniques-in-adult-tbi-part-i-a-scoping-review-of-intermittent-semi-intermittent-methods
#12
Frederick Adam Zeiler, Joseph Donnelly, Leanne Calviello, David Menon, Peter Smieleweski, Marek Czosnyka
To perform a systematic, scoping review of commonly described intermittent/semi-intermittent autoregulation measurement techniques in adult TBI. Nine separate systematic reviews were conducted for each intermittent technique: Computed tomographic perfusion (CTP)/Xenon-CT (Xe-CT), positron emission tomography (PET), magnetic resonance imaging (MRI), arterio-venous difference in oxygen (AVDO2) technique, thigh cuff deflation technique (TCDT), transient hyperemic response test (THRT), orthostatic hypotension test (OHT), mean flow index (Mx) and transfer function ARI (TF-ARI)...
June 24, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28646892/effect-of-acupuncture-on-cerebrovascular-reserve-in-patients-with-acute-cerebral-infarction-protocol-for-a-randomized-controlled-pilot-study
#13
Shaosong Wang, Tingting Ma, Linpeng Wang, Lu Liu, Huilin Liu, Bin Li, Yuanbo Fu
BACKGROUND: The incidence of cerebral infarction has been growing year by year in China and around the world. According to clinical observation, acupuncture utilizing the "waking up the spirit" needling method is widely used in patients with cerebral infarction, though the underlying mechanisms remain unclear. Additionally, a number of studies have begun to focus on the relationship between cerebrovascular reserve (CVR) and cerebral infarction. The present study aims to investigate whether CVR is one of potential mechanisms underpinning this effect of acupuncture on patients with cerebral infarction...
June 24, 2017: Trials
https://www.readbyqxmd.com/read/28619533/-dyslipidemia-management-in-patients-with-high-cardiovascular-risk-in-spain-alma-study
#14
Xavier Pintó, Ferran Trias Vilagut, Joan Rius Taruella, Esther Mairal Sallán
OBJECTIVE: To assess the attitude of primary care (PCPs) and specialized care (SCPs) physicians towards the general set of patients with dyslipidemia, particularly those with cardiovascular risk factors. DESIGN: Observational, descriptive, multi-center study based on a survey. LOCATION: Different healthcare regions in Spain. PARTICIPANTS: 1,402 PCPs, and 596 SCPs. MAIN MEASUREMENTS: Physician's profile, routine practices in the management of patients with dyslipidemia...
June 12, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28619454/carvacrol-clay-hybrids-loaded-into-in-situ-gelling-films
#15
M Tenci, S Rossi, C Aguzzi, E Carazo, G Sandri, M C Bonferoni, P Grisoli, C Viseras, C M Caramella, F Ferrari
The aim of the present work was the development of polymer films loaded with a carvacrol (CVR)/clay hybrid (HYBD) for the delivery of CRV in infected skin ulcer treatment. Different clays were considered: montmorrilonite, halloysite and palygorskite (PHC). CRV incorporation in PHC reduced its volatility. HYBD showed 20% w/w CRV loading capacity and was able to preserve CRV antioxidant properties. HYBD was characterized by improved antimicrobial properties against S. aureus and E. coli and cytocompatibility towards human fibroblasts with respect to pure CRV...
June 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28615420/insulin-resistance-among-obese-middle-aged-is-associated-with-decreased-cerebrovascular-reactivity
#16
Olivia H Frosch, Po Lai Yau, Ricardo S Osorio, Henry Rusinek, Pippa Storey, Antonio Convit
OBJECTIVE: To evaluate differences in cerebrovascular reactivity (CVR) to mild hypercapnia in obese/overweight individuals with and without insulin resistance (IR) compared to comparable lean controls. METHODS: A total of 60 cognitively normal participants (20 lean controls and 24 obese/overweight individuals with and 16 without IR) were evaluated using a high spatial resolution arterial spin labeling MRI technique at rest and during mild hypercapnia. We analyzed group differences in CVR in cerebral cortex and ascertained the relationships between CVR, IR, and body mass index (BMI)...
July 18, 2017: Neurology
https://www.readbyqxmd.com/read/28597991/lack-of-linear-correlation-between-dynamic-and-steady-state-cerebral-autoregulation
#17
Daan L K de Jong, Takashi Tarumi, Jie Liu, Rong Zhang, Jurgen A H R Claassen
KEY POINTS: For correct application and interpretation of cerebral autoregulation (CA) measurements in research and in clinical care, it is essential to understand differences and similarities between dynamic and steady-state CA. The present study found no correlation between dynamic and steady-state CA indices in healthy older adults. There was variability between individuals in all (steady-state and dynamic) autoregulatory indices, ranging from low (almost absent) to highly efficient CA in this healthy population...
June 9, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28595170/clustered-cardiovascular-risk-factors-are-associated-with-inflammatory-markers-in-adolescents
#18
Carla Teixeira Silva, Ana Paula Carlos Cândido, Daniela Pala, Priscila Oliveira Barbosa, George Luiz Lins Machado-Coelho, Fernando Luiz Pereira de Oliveira, Ana Carolina Pinheiro Volp, Renata Nascimento de Freitas
BACKGROUND: Clusters of cardiovascular risk (CVR) factors are associated with an increased risk of developing cardiovascular diseases (CVDs). This cross-sectional study assessed the associations between classic CVR factor clusters and inflammatory markers in Brazilian adolescents. METHODS: Measurements included anthropometric, clinical and biochemical parameters and selected inflammatory markers in 487 adolescents (236 boys/251 girls; 12.06 ± 1.41 years). RESULTS: After stratifying the population by gender and adjusting for potential confounding variables, principal component analysis was performed and it produced 5 independent components in both genders: adiposity, glucose metabolism, blood pressure, high-density lipoprotein (HDL)/triacylglycerols (TG), and cholesterol/low-density lipoprotein...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28588426/effects-of-ramadan-fasting-on-platelet-reactivity-in-diabetic-patients-treated-with-clopidogrel
#19
W Bouida, H Baccouche, M Sassi, Z Dridi, T Chakroun, I Hellara, R Boukef, M Hassine, F Added, R Razgallah, I Khochtali, S Nouira
BACKGROUND: The effects of Ramadan fasting (RF) on clopidogrel antiplatelet inhibition were not previously investigated. The present study evaluated the influence of RF on platelet reactivity in patients with high cardiovascular risk (CVR) in particular those with type 2 diabetes mellitus (DM). METHODS: A total of 98 stable patients with ≥2 CVR factors were recruited. All patients observed RF and were taking clopidogrel at a maintenance dose of 75 mg. Clinical findings and serum lipids data were recorded before Ramadan (Pre-R), at the last week of Ramadan (R) and 4 weeks after the end of Ramadan (Post-R)...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28582393/high-correlation-between-framingham-equations-with-bmi-and-with-lipids-to-estimate-cardiovascular-risks-score-at-baseline-in-hiv-infected-adults-in-the-temprano-trial-anrs-12136-in-c%C3%A3-te-d-ivoire
#20
Calixte Ghehi, Delphine Gabillard, Raoul Moh, Anani Badje, Gérard Menan Kouamé, Eric Oouttara, Hugues Ahibo, Jean Baptiste N'Takpé, Jérôme Lecarrou, Serge Paul Eholié, Xavier Anglaret, Christine Danel
CONTEXT: Data on cardiovascular risk (CVR) score among HIV-infected patients in sub-Saharan Africa are scarce. Our first objective was to compare the CVR score of Framingham utilizing BMI and lipids at baseline, and secondary to assess evolution of CVR score over time at Month 30 in the Temprano trial. METHODS: HIV-infected adults with CD4 <800/mm3 without criteria for initiating ART were included and followed for 30 months in the Temprano trial, which assessed the benefits and risks of early antiretroviral treatment (ART) vs deferred ART...
2017: PloS One
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