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https://www.readbyqxmd.com/read/28619533/-dyslipidemia-management-in-patients-with-high-cardiovascular-risk-in-spain-alma-study
#1
Xavier Pintó, Ferran Trias Vilagut, Joan Rius Taruella, Esther Mairal Sallán
OBJECTIVE: To assess the attitude of primary care (PCPs) and specialized care (SCPs) physicians towards the general set of patients with dyslipidemia, particularly those with cardiovascular risk factors. DESIGN: Observational, descriptive, multi-center study based on a survey. LOCATION: Different healthcare regions in Spain. PARTICIPANTS: 1,402 PCPs, and 596 SCPs. MAIN MEASUREMENTS: Physician's profile, routine practices in the management of patients with dyslipidemia...
June 12, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28619454/carvacrol-clay-hybrids-loaded-into-in-situ-gelling-films
#2
M Tenci, S Rossi, C Aguzzi, E Carazo, G Sandri, M C Bonferoni, P Grisoli, C Viseras, C M Caramella, F Ferrari
The aim of the present work was the development of polymer films loaded with a carvacrol (CVR)/clay hybrid (HYBD) for the delivery of CRV in infected skin ulcer treatment. Different clays were considered: montmorrilonite, halloysite and palygorskite (PHC). CRV incorporation in PHC reduced its volatility. HYBD showed 20% w/w CRV loading capacity and was able to preserve CRV antioxidant properties. HYBD was characterized by improved antimicrobial properties against S. aureus and E. coli and cytocompatibility towards human fibroblasts with respect to pure CRV...
June 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28615420/insulin-resistance-among-obese-middle-aged-is-associated-with-decreased-cerebrovascular-reactivity
#3
Olivia H Frosch, Po Lai Yau, Ricardo S Osorio, Henry Rusinek, Pippa Storey, Antonio Convit
OBJECTIVE: To evaluate differences in cerebrovascular reactivity (CVR) to mild hypercapnia in obese/overweight individuals with and without insulin resistance (IR) compared to comparable lean controls. METHODS: A total of 60 cognitively normal participants (20 lean controls and 24 obese/overweight individuals with and 16 without IR) were evaluated using a high spatial resolution arterial spin labeling MRI technique at rest and during mild hypercapnia. We analyzed group differences in CVR in cerebral cortex and ascertained the relationships between CVR, IR, and body mass index (BMI)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28597991/lack-of-linear-correlation-between-dynamic-and-steady-state-cerebral-autoregulation
#4
Daan L K de Jong, Takashi Tarumi, Jie Liu, Rong Zhang, Jurgen A H R Claassen
The purpose of this study was to investigate the relationship between dynamic (dCA) and steady-state cerebral autoregulation (sCA). In 28 healthy older adults, sCA was quantified by a linear regression slope of proportionate (%) changes in cerebrovascular resistance (CVR) in response to proportionate (%) changes in mean blood pressure (BP) induced by stepwise sodium nitroprusside (SNP) and phenylephrine (PhE) infusion. Cerebral blood flow (CBF) was measured at the internal carotid (ICA) and vertebral (VA) artery and cerebral blood flow velocity (CBFV) at the middle cerebral artery (MCA)...
June 9, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28595170/clustered-cardiovascular-risk-factors-are-associated-with-inflammatory-markers-in-adolescents
#5
Carla Teixeira Silva, Ana Paula Carlos Cândido, Daniela Pala, Priscila Oliveira Barbosa, George Luiz Lins Machado-Coelho, Fernando Luiz Pereira de Oliveira, Ana Carolina Pinheiro Volp, Renata Nascimento de Freitas
BACKGROUND: Clusters of cardiovascular risk (CVR) factors are associated with an increased risk of developing cardiovascular diseases (CVDs). This cross-sectional study assessed the associations between classic CVR factor clusters and inflammatory markers in Brazilian adolescents. METHODS: Measurements included anthropometric, clinical and biochemical parameters and selected inflammatory markers in 487 adolescents (236 boys/251 girls; 12.06 ± 1.41 years). RESULTS: After stratifying the population by gender and adjusting for potential confounding variables, principal component analysis was performed and it produced 5 independent components in both genders: adiposity, glucose metabolism, blood pressure, high-density lipoprotein (HDL)/triacylglycerols (TG), and cholesterol/low-density lipoprotein...
June 9, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28588426/effects-of-ramadan-fasting-on-platelet-reactivity-in-diabetic-patients-treated-with-clopidogrel
#6
W Bouida, H Baccouche, M Sassi, Z Dridi, T Chakroun, I Hellara, R Boukef, M Hassine, F Added, R Razgallah, I Khochtali, S Nouira
BACKGROUND: The effects of Ramadan fasting (RF) on clopidogrel antiplatelet inhibition were not previously investigated. The present study evaluated the influence of RF on platelet reactivity in patients with high cardiovascular risk (CVR) in particular those with type 2 diabetes mellitus (DM). METHODS: A total of 98 stable patients with ≥2 CVR factors were recruited. All patients observed RF and were taking clopidogrel at a maintenance dose of 75 mg. Clinical findings and serum lipids data were recorded before Ramadan (Pre-R), at the last week of Ramadan (R) and 4 weeks after the end of Ramadan (Post-R)...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28582393/high-correlation-between-framingham-equations-with-bmi-and-with-lipids-to-estimate-cardiovascular-risks-score-at-baseline-in-hiv-infected-adults-in-the-temprano-trial-anrs-12136-in-c%C3%A3-te-d-ivoire
#7
Calixte Ghehi, Delphine Gabillard, Raoul Moh, Anani Badje, Gérard Menan Kouamé, Eric Oouttara, Hugues Ahibo, Jean Baptiste N'Takpé, Jérôme Lecarrou, Serge Paul Eholié, Xavier Anglaret, Christine Danel
CONTEXT: Data on cardiovascular risk (CVR) score among HIV-infected patients in sub-Saharan Africa are scarce. Our first objective was to compare the CVR score of Framingham utilizing BMI and lipids at baseline, and secondary to assess evolution of CVR score over time at Month 30 in the Temprano trial. METHODS: HIV-infected adults with CD4 <800/mm3 without criteria for initiating ART were included and followed for 30 months in the Temprano trial, which assessed the benefits and risks of early antiretroviral treatment (ART) vs deferred ART...
2017: PloS One
https://www.readbyqxmd.com/read/28566229/-cardiovascular-risk-and-cardiovascular-events-in-the-general-population-of-the-sanitary-area-of-toledo-ricarto-study
#8
G C Rodríguez-Roca, L Rodríguez-Padial, F J Alonso-Moreno, A Segura-Fragoso, A Villarín-Castro, M L Rodríguez-García, A Menchén-Herreros, G A Rojas-Martelo, J A Fernández-Conde, L M Artigao-Rodenas, J A Carbayo-Herencia, C Escobar-Cervantes, J Hernández-Moreno, J Fernández-Martín
INTRODUCTION: The main aim of this study is to ascertain the prevalence of cardiovascular risk factors (CVRF), target organ damage (TOD), cardiovascular disease (CVD), as well as life habits (physical exercise, alcohol consumption, and Mediterranean diet) in the population of a Health Area in Toledo, Spain, to assess cardiovascular risk (CVR). MATERIAL AND METHODS: Epidemiological and observational study that will analyse a sample from the general population aged 18 years or older, randomly selected from a database of health cards, and stratified by age and gender...
May 26, 2017: Semergen
https://www.readbyqxmd.com/read/28562210/lateral-sinus-dural-arteriovenous-fistulas-sinovenous-outflow-restriction-outweighs-cortical-venous-reflux-as-a-parameter-associated-with-hemorrhage
#9
Yong-Sin Hu, Chung-Jung Lin, Hsiu-Mei Wu, Wan-Yuo Guo, Chao-Bao Luo, Chih-Chun Wu, Wen-Yuh Chung, Kang-Du Liu, Huai-Che Yang, Cheng-Chia Lee
Purpose To investigate whether sinovenous outflow restriction (SOR) is more strongly associated with hemorrhage than cortical venous reflux (CVR) in patients with lateral sinus dural arteriovenous fistulas (DAVFs). Materials and Methods An institutional review board approved this retrospective study and waiver of informed consent was obtained. From 1995 to 2016, 163 cases of lateral sinus DAVFs were included and divided into hemorrhagic and nonhemorrhagic groups based on initial presentation. Their angiograms and magnetic resonance images were evaluated, with two evaluators independently grading CVR and SOR...
May 30, 2017: Radiology
https://www.readbyqxmd.com/read/28560160/application-of-calibrated-fmri-in-alzheimer-s-disease
#10
Isabelle Lajoie, Scott Nugent, Clément Debacker, Kenneth Dyson, Felipe B Tancredi, AmanPreet Badhwar, Sylvie Belleville, Yan Deschaintre, Pierre Bellec, Julien Doyon, Christian Bocti, Serge Gauthier, Douglas Arnold, Marie-Jeanne Kergoat, Howard Chertkow, Oury Monchi, Richard D Hoge
Calibrated fMRI based on arterial spin-labeling (ASL) and blood oxygen-dependent contrast (BOLD), combined with periods of hypercapnia and hyperoxia, can provide information on cerebrovascular reactivity (CVR), resting blood flow (CBF), oxygen extraction fraction (OEF), and resting oxidative metabolism (CMRO2). Vascular and metabolic integrity are believed to be affected in Alzheimer's disease (AD), thus, the use of calibrated fMRI in AD may help understand the disease and monitor therapeutic responses in future clinical trials...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28552207/clinical-perspective-on-antihypertensive-drug-treatment-in-adults-with-grade-1-hypertension-and-low-to-moderate-cardiovascular-risk-an-international-expert-consultation
#11
REVIEW
Alberto Morales Salinas, Antonio Coca, Michael H Olsen, Ramiro A Sanchez, Weimar K Sebba-Barroso, Richard Kones, Vicente Bertomeu-Martinez, Javier Sobrino, Luis Alcocer, Daniel J Pineiro, Fernando Lanas, Carlos A Machado, Fernando Aguirre-Palacios, Jose Ortellado, Gonzalo Perez, Rodrigo Sabio, Orlando Landrove, Delfin Rodriguez-Leyva, Alfredo Duenas-Herrera, Ayelen Rodriguez Portelles, Jose Z Parra-Carrillo, Daniel L Piskorz, Alfonso Bryce-Moncloa, Gabriel Waisman, Yuichiro Yano, Hector Ventura, Marcelo Orias, Dorairaj Prabhakaran, J Sundström, Jiguang Wang, Louise M Burrell, Alta E Schutte, Patricio Lopez-Jaramillo, Eduardo Barbosa, Josep Redon, Michael A Weber, Carl J Lavie, Agustin Ramirez, Pedro Ordunez, Salim Yusuf, Alberto Zanchetti
Hypertension is a leading risk factor for disease burden globally. An unresolved question is whether grade 1 hypertension (140-159/90-99mmHg) with low (cardiovascular mortality <1% at 10 years) to moderate (cardiovascular mortality ≥1% and <5% at 10 years) absolute total cardiovascular risk (CVR) should be treated with antihypertensive agents. A virtual international consultation process was undertaken to summarize the opinions of select experts. After holistic analysis of all epidemiological, clinical, psychosocial, and public health elements, this consultation process reached the following consensus in hypertensive adults aged <80 years: (1) The question of whether drug treatment in grade 1 should be preceded by a period of some weeks or months during which only lifestyle measures are recommended cannot be evidence based, but the consensus opinion is to have a period of lifestyle alone reserved only to patients with grade 1 "isolated" hypertension (grade 1 uncomplicated hypertension with low absolute total CVR, and without other major CVR factors and risk modifiers)...
July 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/28545471/decisional-balance-inventory-dbi-adolescent-form-for-smoking-psychometric-properties-of-the-persian-version
#12
Maryam Khazaee-Pool, Tahereh Pashaei, Ponnet Koen, Fatemeh Jafari, Rashin Alizadeh
BACKGROUND: One effective model for studying cigarette smoking cessation is the transtheoretical model (TTM). In order to assess to what degree interventions can make variations in individuals' behavior, several questionnaires have been developed based on the TTM. This study aims to describe the development of the Persian version of the Decisional Balance Inventory (DBI) for smoking cessation in Iran and to evaluate its psychometric properties. DESIGN AND METHODS: The forward-backward technique was used to translate the DBI from English into Persian...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28529871/subtle-alterations-in-cerebrovascular-reactivity-in-mild-cognitive-impairment-detected-by-graph-theoretical-analysis-and-not-by-the-standard-approach
#13
Carlos A Sánchez-Catasús, Gretel Sanabria-Diaz, Antoon Willemsen, Eduardo Martinez-Montes, Juan Samper-Noa, Angel Aguila-Ruiz, Ronald Boellaard, Peter De Deyn, Rudi A J O Dierckx, Lester Melie-Garcia
There is growing support that cerebrovascular reactivity (CVR) in response to a vasodilatory challenge, also defined as the cerebrovascular reserve, is reduced in Alzheimer's disease dementia. However, this is less clear in patients with mild cognitive impairment (MCI). The current standard analysis may not reflect subtle abnormalities in CVR. In this study, we aimed to investigate vasodilatory-induced changes in the topology of the cerebral blood flow correlation (CBFcorr) network to study possible network-related CVR abnormalities in MCI...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28502973/the-job-competency-of-radiological-technologists-in-korea-based-on-specialists-opinion-and-questionnaire-survey
#14
Chang-Seon Lim, Yang-Sub Lee, Yong-Dae Lee, Hyun-Soo Kim, Gye-Hwan Jin, Seong-Youl Choi, Yera Hur
Purpose: Although there are over 40,000 licensed radiological technologists (RTs) in Korea, job competency standards have yet to be defined. This study aims to clarify the job competency of Korean RTs. Methods: A task force team of 11 professional RTs were recruited in order to analyze the job competency of domestic and international RTs. A draft for the job competency of Korean RTs was prepared. A survey was then conducted sampling RTs and the attitudes of their competencies were recorded from May 21 to July 30, 2016...
May 11, 2017: Journal of Educational Evaluation for Health Professions
https://www.readbyqxmd.com/read/28495396/cardiovascular-risk-prediction-in-chronic-kidney-disease-patients
#15
Santiago Cedeño Mora, Marian Goicoechea, Esther Torres, Úrsula Verdalles, Ana Pérez de José, Eduardo Verde, Soledad García de Vinuesa, José Luño
INTRODUCTION: Scores underestimate the prediction of cardiovascular risk (CVR) as they are not validated in patients with chronic kidney disease (CKD). Two of the most commonly used scores are the Framingham Risk Score (FRS-CVD) and the ASCVD (AHA/ACC 2013). The aim of this study is to evaluate the predictive ability of experiencing a cardiovascular event (CVE) via these 2scores in the CKD population. MATERIAL AND METHODS: Prospective, observational study of 400 prevalent patients with CKD (stages 4 and 5 according the KDOQI; not on dialysis)...
May 8, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28487157/cerebrovascular-reactivity-measured-by-functional-magnetic-resonance-imaging-during-breath-hold-challenge-a-systematic-review
#16
REVIEW
Adam L Urback, Bradley J MacIntosh, Benjamin I Goldstein
Cerebrovascular reactivity (CVR) is the cerebral hemodynamic response to a vasoactive substance. Breath-hold (BH) induced CVR has the advantage of being non-invasive and easy to implement during magnetic resonance imaging (MRI). We systematically reviewed the literature regarding MRI measurement of BH induced CVR. The literature was searched using MEDLINE with the search terms breath-hold; and MRI or cerebrovascular reactivity. The search yielded 2244 results and 54 articles were included. Between-group comparisons have found that CVR was higher among healthy controls than patients with various pathologies (e...
August 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28472140/validation-of-a-diabetes-numeracy-test-in-arabic
#17
Hussah Alghodaier, Hoda Jradi, Najwa Samantha Mohammad, Amen Bawazir
BACKGROUND: The prevalence of diabetes Mellitus in Saudi Arabia is 24%, ranking it among the top ten Worldwide. Diabetes education focuses on self-management and relies on numeracy skills. Poor numeracy may go unrecognized and it is important to have an assessment tool in Arabic to measure such a skill in diabetes care. OBJECTIVES: To validate a 15-item Diabetes Numeracy Test (DNT-15) in the Arabic Language as a tool to assess the numeracy skills of patients with diabetes and to test its properties among Saudi patients with diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28440983/-detection-of-cardiovascular-risk-in-healthcare-workers-on-the-basis-of-who-jnc-7-atp-iii-criteria
#18
Roma Rubí Rodríguez-Reyes, José Eduardo Navarro-Zarza, Tania Leticia Tello-Divicino, Isela Parra-Rojas, Oscar Zaragoza-García, Iris Paola Guzmán-Guzmán
BACKGROUND: Anthropometric and blood pressure measurements are significant parameters in the assessment of cardiovascular risk (CVR). The aim was to establish the distribution of clinical-anthropometric parameters in health care workers according to the criteria established by WHO/JNC 7/ATP III. METHODS: Observational, cross-sectional study in 350 workers of a general hospital. Definitions of anthropometric alterations were made considering the criteria established by WHO and the Asian ATP III, while altered blood pressure was defined by criteria JNC 7 and ATP III...
May 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28438483/what-role-does-rheumatoid-arthritis-disease-activity-have-in-cardiovascular-risk
#19
Marco Aurelio Ramírez Huaranga, María Dolores Mínguez Sanchez, Miguel Ángel Zarca Diaz de la Espina, Pedro José Espinoza Pardos, Guillermo Romero Aguilera
Rheumatoid arthritis (RA) is associated with a 1.3 to 3-fold increase in mortality, being the major cause of death from cardiovascular complications (40%-50%). Therefore, the initial approach should include cardiovascular risk (CVR) assessment using algorithms adapted for this population. Although, SCOREM is an important advance, there are data indicating that subclinical atherosclerosis may be underdiagnosed. OBJECTIVE: To estimate the strength of association between carotid ultrasound and SCOREM in this population, as well as the implication of disease activity...
April 21, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28435625/developing-azeri-aphasia-screening-test-and-preliminary-validity-and-reliability
#20
Sousan Salehi, Ali Jahan, Najva Mousavi, Mazyar Hashemilar, Zohreh Razaghi, Maryam Moghadam-Salimi
Background: As there is no standard aphasia screening tool for Azeri language yet, the aim of this study was to develop an aphasia screening test with acceptable validity and reliability. Methods: The present study was conducted in two phases. In the first phase, by literature search, the screening test was designed and to obtain validity it was peer reviewed by expert panel. After collecting experts' ratings and comments, appropriate modifications were applied. For test-retest reliability in the second phase, edited test was administered in 32 patients with brain injuries, then the retest was performed two weeks later...
October 7, 2016: Iranian Journal of Neurology
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