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genitourinary tuberculosis

Reeta James, S Avudaiappan, A Assistant Professor, Kumar Natarajan, S Chandrasekaran
Multifocal Tuberculosis represents the many faces of an age old disease. It is characterized by the presence of large multifocal tuberculous areas in same or different organs. A 50 year old male patient, presented with features suggestive of renal failure, low grade fever and cough with mucoid expectoration. He was found to have pulmonary TB, genitourinary TB and tuberculous lymphadenitis. He was started on antituberculous treatment to which he showed good response.
September 2016: Journal of the Association of Physicians of India
James Benjamin Gleason, Basheer Tashtoush, Jinesh Mehta, Edward Savage, Felipe Martinez, Atul C Mehta
Extrapulmonary tuberculosis refers to Mycobacterium tuberculosis involving organs other than the lungs (eg, pleura, lymph nodes, genitourinary tract, abdomen, skin, joints and bones, or meninges). In non-HIV-endemic areas, where reactivation is the predominant mechanism of tuberculosis, pleural involvement occurs in 4% of cases. We present an extremely rare case of a 62-year-old immunocompetent patient with pleural tuberculosis confirmed by surgical pleural biopsies, who presented with a large mediastinal mass and evidence of pulmonary artery invasion on CT scanning and endobronchial ultrasonography imaging, highlighting a unique and malignant-like character of the disease...
October 2016: Chest
Sherly Abraham, Dora Ernestina Izaguirre Anariba, Kirandeep Dua, Mohammad Mir, Arvind Ankireddypalli
Genitourinary tuberculosis represents a form of extra-pulmonary tuberculosis that occurs in the kidneys, ureters, seminal vesicles, prostate, testis, vas deferens, and epididymis. Isolated testicular involvement is unusual, and differential diagnosis includes testicular tumor, acute infection, infarction, and granulomatous infection. We report a case of a 36-year-old Ecuadorian man residing in New York, New York, who presented with a painful scrotal mass, weight loss, and purulent discharge from ulcerated lesion in scrotal area 10 years following his immigration to the United States...
June 2016: Therapeutic Advances in Infectious Disease
Upasana Joneja, William R Short, Amity L Roberts
We describe a case of disseminated Mycobacterium tuberculosis (mTB) with prostatic abscess in a newly diagnosed HIV patient in the United States. The patient is a 34 year-old male who presented with respiratory symptoms and was diagnosed with HIV/AIDS complicated by disseminated mTB infection of the lungs, liver, and prostate. His prostate showed abscess formation on imaging that required drainage however he did not present with any genitourinary complaints. Our literature review revealed that prostatic involvement in mTB in the form of granulomatous prostatitis is uncommon; however, abscess formation is extremely rare and only few such cases have been published...
2016: IDCases
Geraldo Bezerra da Silva, Luiz David Salles Brito, Samia Thabida de Oliveira Rabelo, Zenar Maria Ribeiro Mendes de Saboia
Genitourinary tuberculosis (TB) is the third most common form of extrapulmonary TB. A 34-year-old man with severe kidney function loss secondary to renal TB initially presented with urinary symptoms, including dysuria and polacyuria. The diagnosis was based on clinical history and laboratory tests; the urinalysis revealed acid-fast bacilli. The patient's condition stabilized after beginning TB-specific treatment, but the right kidney function loss persisted. Renal TB can lead to irreversible loss of renal function...
May 2016: Revista da Sociedade Brasileira de Medicina Tropical
S Cherif, K Yoganathan, T Banks, R Abdulla
Worldwide, it is estimated that 14.8% of all new tuberculosis cases in adults are attributable to HIV infection. Genitourinary tuberculosis is a known complication and is considered to be a severe form of extrapulmonary tuberculosis. Isolated tuberculous epididymo-orchitis is rare. We report a Caucasian HIV-positive heterosexual male with a clinical diagnosis of testicular tumour for which he underwent a right orchidectomy. Tuberculous epididymo-orchitis was confirmed by histology. In this case, all Immune Reconstitution Inflammatory Syndrome (IRIS) criteria were met...
May 24, 2016: International Journal of STD & AIDS
K Dale, E Tay, P Trevan, J T Denholm
SETTING: The state of Victoria, Australia, is an industrialised setting with low tuberculosis (TB) incidence, universal health care and high levels of migration. OBJECTIVE: To assess case fatality rates (CFRs) and factors associated with death in a cohort of TB cases notified between 2002 and 2013. DESIGN: Retrospective cohort study. Cases who died untreated or during treatment were reviewed to determine whether TB was a primary cause of, contributed to or was unrelated to death...
April 2016: International Journal of Tuberculosis and Lung Disease
Avradip Santra, Falguni Mandi, Abhishek Bandyopadhyay
Genitourinary tuberculosis usually occurs in young adults and the middle-aged and is very uncommon in the paediatric population. It generally presents with haematuria, pyuria, irritative voiding symptoms and flank pain; presentation as a renal mass is highly unusual. We report a two-year-old girl who was referred to the Nil Ratan Sircar Medical College, Kolkata, India, in June 2014 with abdominal pain. Subsequent radiological investigations revealed a left renal hypoechoic mass lesion. A left nephroureterectomy was performed on suspicion of a Wilms' tumour...
February 2016: Sultan Qaboos University Medical Journal
Ankit Kumar Jitani, Jaya Mishra, Stephen L Sailo, Vandana Raphael
Primary lymphoma of the urinary bladder is a rare entity. It has a distinctively different presentation than the urothelial carcinoma, which is the most common form of bladder cancer, but might mimic inflammatory lesions such as tubercular cystitis, clinically as well as radiologically. We present a case of primary extranodal marginal zone lymphoma of the bladder, which was a close mimicker of tuberculosis, leading to delay in diagnosis. We highlight the role of biopsy in prompt diagnosis of these cases. We emphasize on the high index of suspicion required to identify such cases at an early stage, which has pronounced prognostic implications...
January 2016: Urology Annals
Sanjeet Kumar Singh, Anjana Singh, Anant Kumar
Genitourinary tuberculosis (TB) is a common form of extrapulmonary tuberculosis. The kidneys are usually affected by hematogenous seeding at the time of primary pulmonary infection. Genitourinary TB has non-specific clinical presentations and variable radiographic appearances. We are reporting a case of genitourinary TB presenting as bilateral renal mass. The patient underwent computed tomography-guided kidney biopsy that showed a granulomatous lesion. Then, the patient was put on anti-tuberculous treatment with a good response...
January 2016: Saudi Journal of Kidney Diseases and Transplantation
Shveta Narang, Anjali Solanki, Surender Kashyap, Lekha Rani
BACKGROUND: Fine needle aspiration cytology (FNAC) is a precise, cost-effective, and minimal invasive technique for diagnosis of extrapulmonary tuberculosis (EPTB). This study was aimed to analyze clinical and cytological characteristics of EPTB with particular emphasis on pathogenesis. METHODS: This was a retrospective study analyzing 237 cases of EPTB diagnosed on FNAC. Depending on the presence of necrosis and granulomas, cases were divided into three classes...
February 2016: Diagnostic Cytopathology
Subodh Kumar Regmi, Urvashi B Singh, Jai Bhagwan Sharma, Rajeev Kumar
OBJECTIVE: Male partners of infertile women with genital tuberculosis (TB) are often screened for genital TB. We aimed to evaluate the clinical significance of a positive screening semen polymerase chain reaction (PCR) for Mycobacterium tuberculosis test (TB-PCR) in asymptomatic men undergoing infertility evaluation and determine the need for a detailed investigation and treatment for TB. MATERIALS AND METHODS: Between March 2012 and January 2013, male partners of 15 infertile women with a diagnosis of genitourinary TB (GUTB) as the cause of infertility, tested positive either on semen PCR for TB (13 cases), or Mycobacterium Growth Indicator Tube-960 test (2 cases)...
July 2015: Journal of Human Reproductive Sciences
Mustafa Kadihasanoglu, Tekin Yildiz, Safak Atahan, Andrew Ausmus, Ozcan Atahan
Genitourinary tuberculosis (TB) is a common type of extrathoracic TB and can be found in isolation or associated with pulmonary TB. It contributes to 10-14% of extrapulmonary TB. Prostate TB is rare and usually found incidentally following transurethral resection of the prostate for treatment of benign prostatic obstruction as an isolated lesion in immunocompetant patient. The authors report a case of prostatic and pulmonary TB in animmunocompetant patient investigating for the positive positron emission tomography in lung and prostate...
July 2015: Journal of Cancer Research and Therapeutics
Michael W Sourial, Fadi Brimo, Ruth Horn, Sero Andonian
INTRODUCTION: Although tuberculosis (TB) is the most common cause of mortality from infectious diseases worldwide, genitourinary TB in North America is rare. We review 3 cases of genitourinary TB diagnosed within the last 5 years. CASES: The first case is that of a 76-year-old African-Canadian woman who was referred for percutaneous nephrolithotomy of right lower pole renal stones. Although renal TB was suspected, her initial urinary TB culture was negative. On follow-up imaging, she developed bilateral ureteral thickening and ureteroscopic biopsy confirmed necrotizing granulomata...
July 2015: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Seema Awasthi, Manoj Saxena, Faiyaz Ahmad, Ashutosh Kumar, Shyamoli Dutta
BACKGROUND: Abdominal tuberculosis (TB) is the sixth most common form of extra-pulmonary site of infection after lymphatic, genitourinary, bone and joint, miliary and meningeal TB with a rising incidence in recent years. TB can affect any part of the gastro-intestinal (GI) tract including anus, peritoneum and hepato-biliary system. The clinical manifestations of abdominal tuberculosis are non-specific and mimic various GI disorders and cause delay in diagnosis and management. AIM: To evaluate the various clinical, radiological and microbiological findings of abdominal tuberculosis and to define the role of histopathological examination in establishing the diagnosis in resource poor settings and to analyze the compliance and response to anti-tubercular treatment...
May 2015: Journal of Clinical and Diagnostic Research: JCDR
G Vithiya, T Rajendran, Mariappan, Hemant Kumar
Prostate tuberculosis is an infrequent manifestation of genitourinary tuberculosis Complications like prostate abscess, perineal fistula, sinus can occur in immunocompromised individuals. Various predisposing factors like diabetes, bladder outlet obstruction, chronic renal failure can lead to prostate abscess. TRUS (Transrectal USG) is one of the tools useful for the diagnosis of prostatic abscess. We present our case, 57 year man, ethanolic with features of chronic liver disease and pulmonary tuberculosis which disseminated to prostate, developed abscess presenting as pyrexia of unknown origin...
April 2015: Indian Journal of Tuberculosis
S Toccaceli, L Persico Stella, M Diana, A Taccone, G Giuliani, L De Paola, M Valvano, C De Padua, G Di Biasio, C Ranucci, E Orsi, F La Torre
Tuberculosis or TB (tubercle bacillus) remains a major public health problem in developing countries. Over the last decades extrapulmonary locations of the disease have become more frequent due to the increased prevalence of acquired immune deficiency syndrome and the increase number of organ transplants. The urogenital localization represents about 27% of all extra-pulmonary localizations of TB and may be due either to a disseminated infection or to a primitive genitourinary localization. The majority of patients, has pyuria, sometimes with hematuria...
March 2015: Il Giornale di Chirurgia
Hairong Chen, Yubo Liu, Dawei Wu
Genitourinary tuberculosis (GUTB) is difficult to diagnose in the earlier stage owing to the non-specific symptoms. Usually, renal tuberculous involvement is unilateral and the imaging finding is renal calcification, but associated calcifications of bilateral ureter and bladder are rare. We report a 66-year-old man who presented with diffuse calcification of the urinary system (including bilateral pelvicalyceal system, both ureters and bladder) and disseminated miliary tuberculosis due to GUTB. He had been misdiagnosed with urinary tract infection and urinary lithiasis for two years before the diagnosis of GUTB was confirmed by microbiological examination of the urine...
February 2015: Iranian Journal of Public Health
Rajan Gupta, Prabhjot Singh, Rajeev Kumar
OBJECTIVE: Infertility may be the sole manifestation of genitourinary tuberculosis (TB) and men with idiopathic obstructive azoospermia are often screened for TB using semen polymerase chain reaction (PCR) test. We assessed the benefits of such screening. DESIGN: Totally, 100 infertile men with idiopathic obstructive azoospermia were screened with a kit-based PCR for semen TB. Confirmatory tests for TB were performed in PCR positive men before administering anti-tubercular therapy (ATT) for 6 months...
January 2015: Journal of Human Reproductive Sciences
Santosh Kumar, Balchandra D Kashyapi, Shivadeo S Bapat
INTRODUCTION: Genitourinary tuberculosis contributes 15-20% of extra pulmonary tuberculosis. Prostatic tuberculosis is much less common than renal, vesico-seminal and epididymal TB. Predisposing factor include prior tubercular infection, immunocompromised status, previous BCG therapy. Nevertheless, isolated tuberculous prostatic abscess are uncommon especially in immunocompetent patient. PRESENTATION OF CASE: We report a case of tuberculous prostatic abscess in young, healthy immunocompetent patient, from India, who has initial presentation of pyrexia of unknown origin...
2015: International Journal of Surgery Case Reports
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