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Connective tissue graft

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https://www.readbyqxmd.com/read/29241962/engineering-and-repair-of-diaphragm-using-biosheet-a-collagenous-connective-tissue-membrane-in-rabbits
#1
Keisuke Suzuki, Makoto Komura, Kan Terawaki, Tetsuro Kodaka, Takumi Gohara, Hiroko Komura, Yasuhide Nakayama
BACKGROUND: Prosthetic patches can be used to repair large congenital diaphragmatic hernia defects but may be associated with infection, recurrence, and thoracic deformity. Biosheets (collagenous connective tissue membranes) have been used in regenerative medicine. We evaluated the efficacy of Biosheets in a rabbit model. METHODS: Biosheets were prepared by embedding silicone plates in dorsal subcutaneous pouches of rabbits for 4weeks. In group 1 (n=11), Gore-Tex® sheets (1...
November 21, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29240201/coronally-advanced-flap-with-site-specific-application-of-connective-tissue-graft-for-the-treatment-of-multiple-adjacent-gingival-recessions-a-3-year-follow-up-case-series
#2
Martina Stefanini, Giovanni Zucchelli, Matteo Marzadori, Massimo de Sanctis
The aim of this study was to evaluate the short- (1 year) and longer-term (3 years) effectiveness of a surgical procedure combining coronally advanced flap (CAF) with site-specific application of connective tissue graft (CTG) in the treatment of multiple gingival recessions (MGR). A total of 60 periodontally healthy subjects with esthetic complaints due to excessive tooth length presenting multiple (at least three) Miller Class I and II gingival recession defects (≥ 1 mm) affecting adjacent teeth in the maxilla and mandible were enrolled in the study...
January 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29240199/late-dental-implant-failures-associated-with-retained-root-fragments-case-reports-with-histologic-and-sem-analysis
#3
Marc L Nevins, Laureen Langer, Peter Schupbach
Interest has recently developed in the purposeful retention of root fragments with their periodontal apparatus to support bone and soft tissue at immediate implant sites in the esthetic zone. This methodology is designed to avoid bone grafting, connective tissue grafts, and the use of membranes and may have short-term benefits in terms of tissue preservation. However, it is not completely without long-term risks. At times, implants may be unintentionally placed into edentulous sites where root fragments remain...
January 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29235541/biodegradable-bisvinyl-sulfonemethyl-crosslinked-gelatin-conduit-promotes-regeneration-after-peripheral-nerve-injury-in-adult-rats
#4
Chien-Hsin Ko, Ming-You Shie, Jia-Horng Lin, Yi-Wen Chen, Chun-Hsu Yao, Yueh-Sheng Chen
In our previous study, we found that gelatin-based materials exhibit good conductivity and are non-cytotoxic. In this study, gelatin was cross-linked with bisvinyl sulfonemethyl (BVSM) to fabricate a biodegradable conduit for peripheral nerve repair. First, BVSM on the prepared conduit was characterized to determine its mechanical properties and contact angle. The maximum tensile strength and water contact angle of the gelatin-BVSM conduits were 23 ± 4.8 MPa and 74.7 ± 9°, which provided sufficient mechanical strength to resist muscular contraction; additionally, the surface was hydrophilic...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29229072/the-role-of-subepithelial-connective-tissue-graft-for-reconstruction-of-interdental-papilla-clinical-study
#5
Ena Sharma, Anuj Sharma, Kamaljit Singh
BACKGROUND: The ideal goal of periodontal therapy is regeneration of the lost periodontium. However regeneration of the lost interdental papilla has been elusive. Therefore the ability of rebuilding lost papillae in the maxillary segment has become one of the major challenges in periodontal plastic surgery. OBJECTIVES OF THE STUDY: To evaluate the success and predictability of surgical technique using a sub epithelial connective tissue graft interposed in a coronally displaced flap to reconstruct the lost interdental papillae...
December 2017: Singapore Dental Journal
https://www.readbyqxmd.com/read/29223663/patch-esophagoplasty-using-an-in-body-tissue-engineered-collagenous-connective-tissue-membrane
#6
Hiroomi Okuyama, Satoshi Umeda, Yuichi Takama, Takeshi Terasawa, Yasuhide Nakayama
AIM: Although many approaches to esophageal replacement have been investigated, these efforts have thus far only met limited success. In-body-tissue-engineered connective tissue tubes have been reported to be effective as vascular replacement grafts. The aim of this study was to investigate the usefulness of an In-body-tissue-engineered collagenous connective tissue membrane, "Biosheet", as a novel esophageal scaffold in a beagle model. METHODS: We prepared Biosheets by embedding specially designed molds into subcutaneous pouches in beagles...
November 13, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29209690/prosthetic-rehabilitation-involving-the-use-of-implants-following-a-fibula-free-flap-reconstruction-in-the-treatment-of-osteosarcoma-of-the-maxilla-a-case-report
#7
E Brauner, A Quarato, F De Angelis, G Pompa, S Jamshir, V Valentini, S Di Carlo
INTRODUCTION: Osteosarcoma is an aggressive primary bone tumor composed of connective tissue cells directly producing osteoid and bone. Prosthetic rehabilitations in post-oncological patients after bone reconstruction are not substantially different than those of patients affected by severe atrophy of upper or lower jaw after bone reconstruction. The treatment for patients with a malignant neoplasia of the oral cavity requires multidisciplinary approach by a team of different specialists that follow the patient through the phases of diagnosis, therapy and oral rehabilitation...
November 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29205140/autologous-fat-transplantation-for-secondary-breast-reconstruction-our-experience
#8
F Simonacci, M P Grieco, N Bertozzi, E Raposio
BACKGROUND: Autologous fat transplantation is used after breast reconstruction to improve the breast profile. There are a variety of different methods used for fat harvesting, preparation, and reinjection. This study describes the specific techniques we used in this series of autologous fat transplantations in breast reconstruction patients and reports their outcomes compared with other studies in the literature. PATIENTS AND METHODS: At the University Hospital of Parma between May 2012 and December 2016, we performed 53 autologous fat transplantations for secondary breast reconstruction patients with an average age of 49 years (range: 34-65 y)...
May 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29188700/dual-role-of-subepithelial-connective-tissue-grafting-in-regeneration-of-periodontal-attachment-apparatus
#9
Nettemu Sunil Kumar, Nettem Sowmya, Vijendra Pal Singh, Madhu B Verma
Periodontal plastic and aesthetic surgery are gaining significant momentum owing to the increasing aesthetic demands by patients. Along with the fulfilment of aesthetic needs, it is imperative that clinicians also enhance function. From these two important viewpoints, subepithelial connective tissue grafting remains an optimum treatment choice for periodontists when treating gingival recession defects accompanied by periodontal attachment apparatus breakdown. Clinical relevance: Subepithelial connective tissue grafting is a successful procedure in its dual role of gingival recession coverage and predictable periodontal regeneration...
May 2017: Dental Update
https://www.readbyqxmd.com/read/29146096/ten-year-review-of-isolated-spontaneous-mesenteric-arterial-dissections
#10
Courtney E Morgan, Neel A Mansukhani, Mark K Eskandari, Heron E Rodriguez
OBJECTIVE: Isolated spontaneous dissection of the superior mesenteric artery (SMA) and celiac artery (CA) remains a rare condition; however, it has been increasingly noted incidentally on diagnostic imaging. The purpose of this study was to examine the natural history and outcomes of patients presenting with isolated spontaneous mesenteric artery dissection (SMAD). We hypothesized that most SMADs can be treated nonoperatively. METHODS: This was a single-center retrospective review of patients presenting with the diagnosis of SMAD between 2006 and 2016...
November 13, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29133624/histopathological-histomorphometrical-and-radiological-evaluations-of-hydroxyapatite-bioactive-glass-and-fluorapatite-bioactive-glass-nanocomposite-foams-as-cell-scaffolds-in-rat-tibia-an-in-vivo-study
#11
Maryam Seyedmajidi, Sina Haghanifar, Karimollah Hajian-Tilaki, Seyedali Seyedmajidi
Bone defects are common and persistent problems in clinical orthopedics and dentistry. The development of synthetic reconstruction materials is essential owing to the restricted access to natural bone grafts, disease transmission risks, surgical costs, donor-site morbidity, infections, and immune response-related complications. Accordingly, the aim of the present study was to evaluate the histopathological, histomorphometrical, and radiological characteristics of composite foams containing hydroxyapatite/bioactive glass (HA/BG) and fluorapatite/bioactive glass (FA/BG) as cell scaffolds in rat tibia reconstruction...
November 14, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/29123002/peritoneal-dialysis-catheter-removal-post-transplant-a-rare-case-of-delayed-bowel-perforation
#12
Andrew P Maxted, Brian Davies, Daniel Colliver, Alun Williams, Andrew Lunn
Peritoneal dialysis (PD) is a well-established form of renal replacement therapy and the practice of leaving catheters in situ post-transplantation widely accepted. We present a rare complication: a child presenting with anal protrusion of the PD catheter.The patient is an 11-year-old boy with a background of renal dysplasia and congenital cutis laxa. Twenty-three weeks after dialysis was commenced, the patient underwent a renal transplant. Thirteen weeks post-transplant, the patient felt an unusual sensation after defecation...
November 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29115019/cell-laden-composite-suture-threads-for-repairing-damaged-tendons
#13
Raquel Costa-Almeida, Rui M A Domingues, Afsoon Fallahi, Huseyin Avci, Iman K Yazdi, Mohsen Akbari, Rui L Reis, Ali Tamayol, Manuela E Gomes, Ali Khademhosseini
Tendons have limited regenerative capacity due to their low cellularity and hypovascular nature, which results in poor clinical outcomes of presently used therapies. As tendon injuries are often observed in active adults, it poses an increasing socio-economic burden on healthcare systems. Currently, suture threads are used during surgical repair to anchor the tissue graft or to connect injured ends. Here, we created composite suture threads coated with a layer of cell-laden hydrogel that can be used for bridging the injured tissue aiming at tendon regeneration...
November 8, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29100829/prospective-and-randomized-evaluation-of-chronos-and-bio-oss-in-human-maxillary-sinuses-histomorphometric-and-immunohistochemical-assignment-for-runx-2-vascular-endothelial-growth-factor-and-osteocalcin
#14
João Paulo Bonardi, Rodrigo Dos Santos Pereira, Fernanda Brasil Jorge Daura Boos, Leonarod Perez Faverani, Geraldo Luiz Griza, Roberta Okamoto, Eduardo Hochuli-Vieira
PURPOSE: The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition to an autogenous bone graft in a 1:1 ratio in human maxillary sinus bone augmentation. MATERIALS AND METHODS: Thirty maxillary sinuses were divided in 5 groups: group 1 included 6 maxillary sinuses grafted with autogenous bone graft alone; group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ratio; group 4 included 6 maxillary sinuses grafted with Bio-Oss; and group 5 included 6 maxillary sinuses grafted with Bio-Oss and autogenous bone graft in a 1:1 ratio...
October 10, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29080078/blood-flow-changes-using-a-3d-xenogeneic-collagen-matrix-or-a-subepithelial-connective-tissue-graft-for-root-coverage-procedures-a-pilot-study
#15
Nikolaos Tatarakis, Nikolaos Gkranias, Ulpee Darbar, Nikolaos Donos
BACKGROUND: The study investigated the early healing process following the treatment of single Miller class I and II recessions with a 3D xenogeneic collagen matrix (CMX) or connective tissue graft (CTG). METHODS: This pilot investigation was designed as a single-center randomized controlled parallel trial. A total of eight subjects (four per group) were treated with either CMX or CTG in the anterior maxilla. Vascular flow changes were assessed by laser Doppler flowmetry (LDF) before and after surgery and at days 1, 2, 3, 7, 14, and 30 while clinical evaluations took place at baseline and at days 60 and 180...
October 27, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29064767/healing-at-the-interface-between-autologous-block-bone-grafts-and-recipient-sites-using-n-butyl-2-cyanoacrylate-as-fixation-histomorphometric-study-in-rabbits
#16
Enzo De Santis, Erick Ricardo Silva, Evandro Neto Carneiro Martins, Riccardo Favero, Daniele Botticelli, Samuel Porfirio Xavier
The aim of the present study was to describe the sequential healing in the interface between autologous bone grafts and recipient parent bone, fixed using an n-butyl-2-cyanoacrylate adhesive, with or without an additional titanium fixation screw. Bone grafts were collected from the calvaria and fixed to the lateral aspect of the mandible in 24 rabbits. The cortical layers of the recipient sites were perforated and the grafts were randomly fixed using an n-butyl-2-cyanocrylate adhesive, either alone or in conjunction with a titanium fixation screw...
October 24, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29058592/ureteral-reconstruction-using-a-tapered-non-vascularized-bladder-graft-an-experimental-study-in-a-canine-animal-model
#17
Lujia Zou, Shanhua Mao, Shenghua Liu, Limin Zhang, Tian Yang, Yun Hu, Qiang Ding, Haowen Jiang
BACKGROUND: Reconstruction of ureteral defects and strictures remains problematic for urologists. We aimed to investigate the possibility of a tapered non-vascularized bladder graft as a novel substitute for ureteral reconstruction. METHODS: This experimental study was conducted on nine beagles. Under general anesthesia, a full-thickness graft with 5-6 cm in length was disassociated from the anterior upper wall of the bladder, and tapered into 1/3 to 1/2 thickness, remaining the urothelial surface...
October 23, 2017: BMC Urology
https://www.readbyqxmd.com/read/29055380/piezoelectric-material-a-promising-approach-for-bone-and-cartilage-regeneration
#18
Namdev More, Govinda Kapusetti
Bone and cartilage are major weight-bearing connective tissues in human and possesses utmost vulnerability for degeneration. The potential causes are mechanical trauma, cancer and disease condition like osteoarthritis and osteoporosis, etc. The regeneration/repair is a challenging, since their complex structures and activities. Current treatment options comprise of auto graft, allograft, artificial bone substituent, autologous chondrocyte implantation, mosaicplasty, marrow stimulation and tissue engineering...
October 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29050128/-lung-transplantation-for-connective-tissue-disease-associated-interstitial-lung-disease-recipient
#19
J Zhang, B Wu, M Zhou, D Liu, L Fan, D Wei, H Yang, J Y Chen
Objective: To investigate the timing and complications of lung transplantation for the treatment of connective tissue disease-associated interstitial lung disease (CTD-ILD). Method: The clinical data of connective tissue-associated disease lung transplantation recipients from September, 2015 to February, 2017 were collected. Results: 11 patients with CTD-ILD were evaluated by lung transplantation and were treated with lung transplantation. Including 2 cases dermatomyositis/polymyositis and interstitial lung disease (PM/DM-ILD), 4 cases rheumatoid arthritis and interstitial lung disease (RA-ILD), 4 cases of primary Sjgren's syndrome and interstitial lung disease (pSS-ILD), 1 case of systemic sclerosis and interstitial lung disease (SSc-ILD)...
October 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29047409/novel-approach-to-gastric-mucosal-defect-repair-using-fresh-amniotic-membrane-allograft-in-dogs-experimental-study
#20
Haithem A Farghali, Naglaa A AbdElKader, Marwa S Khattab, Huda O AbuBakr
BACKGROUND: Gastric mucosal defect could result from several causative factors including the use of nonsteroidal anti-inflammatory drugs, Helicobacter pylori infection, gastrointestinal and spinal cord diseases, and neoplasia. This study was performed to achieve a novel simple, inexpensive, and effective surgical technique for the repair of gastric mucosal defect. METHODS: Six adult male mongrel dogs were divided into two groups (three dogs each). In the control positive group (C + ve), dogs were subjected to surgical induction of gastric mucosal defect and then treated using traditional medicinal treatment for such a condition...
October 18, 2017: Stem Cell Research & Therapy
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