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Connective tissue graft

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https://www.readbyqxmd.com/read/28214498/vasculitic-and-autoimmune-wounds
#1
REVIEW
Victoria K Shanmugam, Divya Angra, Hamza Rahimi, Sean McNish
OBJECTIVE: Chronic wounds are a major cause of morbidity and mortality. Approximately 20% to 23% of nonhealing wounds that are refractory to vascular intervention have other causes, including vasculitis, pyoderma gangrenosum, and other autoimmune diseases. The purpose of this article was to review the literature across medical and surgical specialties with regard to refractory chronic wounds associated with vasculitis and autoimmune diseases and to delineate clinical outcomes of these wounds in response to vascular and other interventions...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28209380/space-maintaining-management-in-maxillary-sinus-lifting-a-novel-technique-using-a-resorbable-polymeric-thermo-reversible-gel
#2
G Cossellu, G Farronato, D Farronato, G Ceschel, F Angiero
Several techniques have been proposed to achieve sinus floor elevation and the formation of new bone through the grafting of autologous, heterologous, or alloplastic materials. The grafted materials act as a scaffold for bone formation inside the maxillary sinus. This study investigated a non-graft sinus lifting procedure using a resorbable polymeric thermo-reversible gel. A space-maintaining approach to sinus lifting, using a resorbable polymeric thermo-reversible gel, was applied in 11 patients undergoing implant treatment in the atrophic posterior maxilla...
February 10, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28207598/newly-formed-bone-induced-by-recombinant-human-bone-morphogenetic-protein-2-a-histological-observation
#3
Azumi Hirata, Takaaki Ueno, Peter K Moy
PURPOSE: To observe, histologically, bone induced by recombinant human bone morphogenetic protein-2 (rhBMP-2) in onlay grafted and sinus lifted alveolaris. MATERIAL AND METHODS: Eighteen patients were treated with rhBMP-2 at concentration 1.5 mg/mL with an absorbable collagen sponge (ACS). The treated bone was harvested with small trephine bur at 5 or 7 months after surgery for the micro Computer Scanning (CT) and light microscopic observation. RESULTS: Micro CT showed clearly 3-dimensional trabecular bone structure...
February 14, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28203026/-histomorphometric-evaluation-of-ridge-preservation-after-molar-tooth-extraction
#4
Y L Zhan, W J Hu, T Xu, M Zhen, R F Lu
OBJECTIVE: To evaluate bone formation in human extraction sockets with absorbed surrounding walls augmented with Bio-Oss and Bio-Gide after a 6-month healing period by histologic and histomorphometric analyses. METHODS: Six fresh molar tooth extraction sockets in 6 patients who required periodontally compromised moral tooth extraction were included in this study. The six fresh extraction sockets were grafted with Bio-Oss particle covered with Bio-Gide. The 2.8 mm×6...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28196169/the-use-of-platelet-rich-fibrin-versus-subepithelial-connective-tissue-graft-in-treatment-of-multiple-gingival-recessions-a-randomized-clinical-trial
#5
Elif Öncü
The objective of this study was to evaluate the clinical effectiveness of platelet-rich fibrin (PRF) membrane used in combination with a modified coronally advanced flap (MCAF) and to compare it with the use of a subepithelial connective tissue graft (SCTG) in combination with a MCAF in treatment of Miller Class I and II bilateral multiple gingival recessions. A total of 20 patients with multiple Miller Class I and II maxillary gingival recession defects participated in this randomized, split-mouth, controlled study...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28196152/human-histologic-evidence-of-reosseointegration-around-an-implant-affected-with-peri-implantitis-following-decontamination-with-sterile-saline-and-antiseptics-a-case-history-report
#6
Paul Fletcher, Daniel Deluiz, Eduardo Mb Tinoco, John L Ricci, Dennis P Tarnow, Justine Monnerat Tinoco
The treatment of peri-implant disease is one of the most controversial topics in implant dentistry. The multifactorial etiology and the myriad proposed techniques for managing the problem make successful decontamination of an implant surface affected by peri-implantitis one of the more unpredictable challenges dental practitioners have to face. This article presents the first known published case report demonstrating human histologic evidence of reosseointegration using a plastic curette for mechanical debridement and dilute sodium hypochlorite, hydrogen peroxide, and sterile saline for chemical detoxification...
February 14, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28194536/the-role-of-vasculature-in-bone-development-regeneration-and-proper-systemic-functioning
#7
REVIEW
Joanna Filipowska, Krzysztof A Tomaszewski, Łukasz Niedźwiedzki, Jerzy A Walocha, Tadeusz Niedźwiedzki
Bone is a richly vascularized connective tissue. As the main source of oxygen, nutrients, hormones, neurotransmitters and growth factors delivered to the bone cells, vasculature is indispensable for appropriate bone development, regeneration and remodeling. Bone vasculature also orchestrates the process of hematopoiesis. Blood supply to the skeletal system is provided by the networks of arteries and arterioles, having distinct molecular characteristics and localizations within the bone structures. Blood vessels of the bone develop through the process of angiogenesis, taking place through different, bone-specific mechanisms...
February 13, 2017: Angiogenesis
https://www.readbyqxmd.com/read/28155051/a-review-on-animal-models-and-treatments-for-the-reconstruction-of-achilles-and-flexor-tendons
#8
Marta Bottagisio, Arianna B Lovati
Tendon is a connective tissue mainly composed of collagen fibers with peculiar mechanical properties essential to functional movements. The increasing incidence of tendon traumatic injuries and ruptures-associated or not with the loss of tissue-falls on the growing interest in the field of tissue engineering and regenerative medicine. The use of animal models is mandatory to deepen the knowledge of the tendon healing response to severe damages or acute transections. Thus, the selection of preclinical models is crucial to ensure a successful translation of effective and safe innovative treatments to the clinical practice...
March 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28117853/soft-and-hard-tissue-management-%C3%A2-in-the-treatment-of-a-discolored-%C3%A2-single-tooth-in-the-esthetic-zone
#9
David Garcia-Baeza, Ramon Garcia-Adamez, Carlos Saavedra
When treating the color of a single tooth in the esthetic zone, it is a complex task to achieve the same visual effect as the rest of the teeth. In addition to the problem of the clinical crown color, if the patient has a thin periodontal biotype it is necessary to manipulate both the hard and soft tissue to achieve a good esthetic result. To change the biotype, a connective tissue graft needs to be performed. The graft must be stabilized exactly where it is needed, and the recipient area modified. The tooth needs to receive an adequate preparation so as to make the restoration thick enough to naturally mask the treated tooth, while also ensuring long-term stability...
2017: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/28110458/experimental-evaluation-of-new-chitin-chitosan-graft-for-duraplasty
#10
M Pogorielov, A Kravtsova, G C Reilly, V Deineka, G Tetteh, O Kalinkevich, O Pogorielova, R Moskalenko, G Tkach
Natural materials such as collagen and alginate have promising applications as dural graft substitutes. These materials are able to restore the dural defect and create optimal conditions for the development of connective tissue at the site of injury. A promising material for biomedical applications is chitosan-a linear polysaccharide obtained by the deacetylation of chitin. It has been found to be nontoxic, biodegradable, biofunctional and biocompatible in addition to having antimicrobial characteristics. In this study we designed new chitin-chitosan substitutes for dura mater closure and evaluated their effectiveness and safety...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28107560/randomized-controlled-clinical-study-comparing-a-volume-stable-collagen-matrix-to-autogenous-connective-tissue-grafts-for-soft-tissue-augmentation-at-implant-sites-linear-volumetric-soft-tissue-changes-up-to-3-months
#11
Marco Zeltner, Ronald E Jung, Christoph H F Hämmerle, Jürg Hüsler, Daniel S Thoma
AIM: to test whether or not the use of a volume stable collagen matrix (VCMX) results in soft tissue volume increase at implant sites non-inferior to an autogenous subepithelial connective tissue graft (SCTG). METHODS: In 20 patients soft tissue augmentation at implant sites was performed using VCMX or SCTG. Casts obtained prior to augmentation (BL), at 30 (FU-30) and 90 days (FU-90) were digitized and transferred to stereolithography (STL) files. BL, FU-30 and FU-90 STL files were superimposed and linear volumetric changes evaluated in crestal and buccal regions of interest (ROI)...
January 20, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28097486/the-therapeutic-effectiveness-of-delayed-fetal-spinal-cord-tissue-transplantation-on-respiratory-function-following-mid-cervical-spinal-cord-injury
#12
Chia-Ching Lin, Sih-Rong Lai, Yu-Han Shao, Chun-Lin Chen, Kun-Ze Lee
Respiratory impairment due to damage of the spinal respiratory motoneurons and interruption of the descending drives from brainstem premotor neurons to spinal respiratory motoneurons is the leading cause of morbidity and mortality following cervical spinal cord injury. The present study was designed to evaluate the therapeutic effectiveness of delayed transplantation of fetal spinal cord (FSC) tissue on respiratory function in rats with mid-cervical spinal cord injury. Embryonic day-14 rat FSC tissue was transplanted into a C4 spinal cord hemilesion cavity in adult male rats at 1 week postinjury...
January 17, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28092776/periosteum-tissue-engineering-in-an-orthotopic-in%C3%A2-vivo-platform
#13
J G Baldwin, F Wagner, L C Martine, B M Holzapfel, C Theodoropoulos, O Bas, F M Savi, C Werner, E M De-Juan-Pardo, D W Hutmacher
The periosteum plays a critical role in bone homeostasis and regeneration. It contains a vascular component that provides vital blood supply to the cortical bone and an osteogenic niche that acts as a source of bone-forming cells. Periosteal grafts have shown promise in the regeneration of critical size defects, however their limited availability restricts their widespread clinical application. Only a small number of tissue-engineered periosteum constructs (TEPCs) have been reported in the literature. A current challenge in the development of appropriate TEPCs is a lack of pre-clinical models in which they can reliably be evaluated...
March 2017: Biomaterials
https://www.readbyqxmd.com/read/28076887/in-vivo-bone-tunnel-evaluation-of-nanoparticle-grafts-using-an-acl-reconstruction-rabbit-model
#14
Sheila A Grant, Sarah E Smith, Hilary Schmidt, Ferris Pfeiffer, Kei Kuroki, Seth Sherman, Richard White, David A Grant
Acellular human gracilis tendons conjugated with gold nanoparticles (AuNP) and hydroxyapatite nanoparticles (nano-HAp) were used as a graft in an anterior cruciate ligament (ACL) reconstruction rabbit model. The ACLs of 11 New Zealand rabbits were reconstructed using grafts conjugated without nanoparticles, with AuNP only, and with both AuNP and nano-HAp. Semi-quantitative histological scoring of bone tunnel portion of grafts was performed after 14 weeks. Bone tunnels were scored for graft degeneration, graft remodeling, percentage of new host fibrous connective, collateral connection, head-to-head connection, graft collagen fiber organization, new host fibrous connective tissue organization, and graft and interface vascularity...
January 11, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28050832/monitoring-vascular-regeneration-and-xylem-connectivity-in-arabidopsis-thaliana
#15
Charles W Melnyk
Plants have a remarkable ability to regenerate vascular tissue after damage or wounding. A striking example of this phenomenon is the cutting and rejoining of plants during the process of grafting, which humans have used for millennia. Here, I describe how to graft Arabidopsis seedlings and how to monitor the vascular reconnection process during wound healing using fluorescent dyes and fluorescent proteins. Furthermore, I describe how to visualize xylem formation during graft healing. These techniques are useful for studying how the vascular system regenerates and for better understanding the process of plant grafting...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28039700/extended-hepatectomy-using-the-bipolar-tissue-sealer-an-experimental-model-of-small-for-size-syndrome-in-pigs
#16
Antonios Athanasiou, Michael Kontos, Emmanouil Pikoulis, John Griniatsos, Apostolos Papalois, Eleftherios Spartalis, Demetrios Moris, Evangelos Felekouras, Theodoros Liakakos
PURPOSE: After liver transplantation with a small-for-size liver graft or after extensive hepatectomy for liver malignancies or other non malignant conditions with an insufficient liver volume, the survival of patients depends on liver regeneration. This study was carried out in order to create a new porcine model for the study of small-for-size syndrome (SFSS) after extensive hepatectomy. METHODS: In the present study we used 23 domestic Landrace pigs weighing 28...
November 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28026732/-spontaneous-tendon-ruptures-in-the-rheumatoid-hand
#17
J Pech, D Veigl, M Vlček
A spontaneous tendon rupture is a direct consequence of rheumatoid inflammation and can appear without any noticeable impact, often during sleep. The patient then presents with inability to flex or extend metacarpophalageal or interphalangeal joints. Multiple ruptures resulting in impaired function of several fingers can also occur and markedly limit the hand's grip strength. A tear may arise from either mechanical injury to the tendon along its course over bone or connective tissues, or by biochemical action of lysosomal enzymes, released during the inflammation process, on the connective tissue of the tendon...
2016: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28018069/bilateral-sequential-knee-dislocation-in-a-patient-with-connective-tissue-disorder-report-of-an-unusual-case-and-lessons-learnt
#18
Waheeb Al-Azzani, Konrad Wronka, James Lewis, Adel Ghandour, Angus Robertson
Tibiofemoral knee dislocation is a rare but serious limb-threatening injury. Without prompt recognition and management, amputation or long-term functional impairment may result. The authors present a case of bilateral sequential knee dislocation, secondary to low-energy trauma, in a patient with Systemic Lupus Erythematosus and antiphospholipid syndrome. Adequate stability was achieved on both occasions by reconstruction of the postero-lateral corner and MCL. During the first reconstruction, ipsi-lateral autograft, as well as hamstring tendons from the contra-lateral side, were used to strengthen the graft...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28005787/nasopalatine-island-advancement-flap
#19
Amin Rahpeyma, Saeedeh Khajehahmadi
BACKGROUND: Anterior maxilla is a high esthetic region of the mouth. Some flaps are introduced for bone graft coverage, mainly based on secondary epithelization of connective tissue-periosteal tissues. This article evaluates the versatility of a new mucoperiosteal flap for reproducible coverage in anterior maxilla. METHODS: In 5 mongrel dogs a 5 mm width mucosal defect in labial mucosa was created after extraction of upper jaw incisors. Nasopalatine island advancement flap was used for mucosal replacement...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005765/functional-reconstruction-in-mandibular-avulsion-injuries
#20
Yoav Leiser, Dekel Shilo, Amir Wolff, Adi Rachmiel
The present report describes the planning and surgery as well as pitfalls and management of a patient with a near total mandibular avulsion injury that was rehabilitated using three-dimensional (3D) laser printing of a titanium lower jaw. Laser-sintering involves zapping layers of powdered metal to recreate a 3D implantable skeletal defect. The process involves using either mirror imaging of the unaffected side or using archival image database of healthy individuals. A 25-year-old man presented with a gunshot injury that left him with a near total avulsed mandible...
November 2016: Journal of Craniofacial Surgery
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