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Connective tissue graft

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https://www.readbyqxmd.com/read/27922959/the-local-effect-of-puerarin-on-critical-sized-calvarial-defects
#1
Çiğdem Coşkun Türer, Akif Türer, Mustafa Cenk Durmuşlar, Mehmet Emin Önger
Pueraria, the root of Pueraria lobata, is a commonly used herb in alternative medicine. This study evaluates the effect of puerarin and autogenous graft material combination on bone regeneration in calvarial critical-sized bone defects. Twenty-four rats were randomly divided into 3 groups of 8 rats each. A 5-mm diameter critical-sized defect was created in the calvarium of each animal. In group C, defects were left unfilled and were allowed to heal spontaneously without the use of any grafting material. Critical-sized bone defect created in animals receiving no treatment...
December 5, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27912139/repair-of-calvarial-bone-defects-in-mice-using-electrospun-polystyrene-scaffolds-combined-with-%C3%AE-tcp-or-gold-nanoparticles
#2
Lisa Terranova, Diana Maria Dragusin, Romain Mallet, Eugeniu Vasile, Izabela-Cristina Stancu, Catherine Behets, Daniel Chappard
Non-biodegradable porous polystyrene (PS) scaffolds, composed of microfibers, have been prepared by electrospinning for the reconstruction of large bone defects. PS microfibers were prepared by incorporating β-TCP grains inside the polymer or grafting gold nanoparticles surface functionalized with mercaptosuccinic acid. Cytocompatibility of the three types of scaffolds (PS, β-TCP-PS and Au-PS) was studied by seeding human mesenchymal stem cells. Biocompatibility was evaluated by implanting β-TCP-PS and Au-PS scaffolds into a critical size (4mm) calvarial defect in mice...
November 8, 2016: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/27891301/how-far-have-we-come-in-the-field-of-nerve-regeneration-after-trigeminal-nerve-injury
#3
REVIEW
Annika Rosén, Arezo Tardast, Tie-Jun Shi
Patients suffering from nerve injury with sensory disturbances or orofacial pain have greatly reduced quality of life, and it is a big cost for the society. Abnormal sensations caused by trigeminal nerve injury often become chronic, severely debilitating, and extremely difficult to treat. In general, non-invasive treatment such as drug treatment has been insufficient, and there are currently few available effective treatments. Surgical interventions such as end-to-end connection or nerve grafting have disadvantages such as donor site morbidity or formation of neuroma...
2016: Current Oral Health Reports
https://www.readbyqxmd.com/read/27882310/minimal-invasive-horizontal-ridge-augmentation-using-subperiosteal-tunneling-technique
#4
Hyun-Suk Kim, Young-Kyun Kim, Pil-Young Yun
BACKGROUND: The goal of this study was to retrospectively evaluate the prognosis of minimal invasive horizontal ridge augmentation (MIHRA) technique using small incision and subperiosteal tunneling technique. METHODS: This study targeted 25 partially edentulous patients (10 males and 15 females, mean age 48.8 ± 19.7 years) who needed bone graft for installation of the implants due to alveolar bone deficiency. The patients took the radiographic exam, panoramic and periapical view at first visit, and had implant fixture installation surgery...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27873018/soft-tissue-augmentation-around-osseointegrated-and-uncovered-dental-implants-a-systematic-review
#5
REVIEW
Renzo G Bassetti, Alexandra Stähli, Mario A Bassetti, Anton Sculean
OBJECTIVES: The aim was to compile the current knowledge about the efficacy of different soft tissue correction methods around osseointegrated, already uncovered and/or loaded (OU/L) implants with insufficient soft tissue conditions. Procedures to increase peri-implant keratinized mucosa (KM) width and/or soft tissue volume were considered. MATERIALS AND METHODS: Screening of two databases: MEDLINE (PubMed) and EMBASE (OVID), and manual search of articles were performed...
November 21, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27859471/volumetric-changes-at-pontic-sites-with-or-without-soft-tissue-grafting-a-controlled-clinical-study-with-a-10-year-follow-up
#6
Stefan P Bienz, Irena Sailer, Ignacio Sanz-Martin, Ronald E Jung, Christoph H F Hämmerle, Daniel S Thoma
OBJECTIVE: to evaluate volumetric changes of soft tissues at pontic sites in patients treated with or without soft tissue grafting over an observation period of 10 years. MATERIALS AND METHODS: A total of 17 patients receiving a tooth-borne fixed dental prosthesis (FDP) were enrolled in this study. Nine patients received a subepithelial connective tissue graft at the pontic site (test). Eight patients continued without soft tissue grafting (control). Baseline impressions were taken after delivery of the final FDP and at 10 years...
November 17, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27834120/2-year-assessment-of-tissue-bioestimulation-with-low-level-laser-on-the-outcomes-of-connective-tissue-graft-in-the-treatment-of-single-gingival-recession-randomized-clinical-trial
#7
Mauro Pedrine Santamaria, Stephanie Botti Fernandes-Dias, Cassia Fernandes Araújo, Felipe Lucas da Silva Neves, Ingrid Fernandes Mathias, Naira Maria Rebelato Bechara Andere, Maria Aparecida Neves Jardini
BACKGROUND: Periodontal wound healing has been accelerated by different low-level laser therapy (LLLT) protocols. However, just few studies evaluated the use of this therapy as adjunctive for periodontal plastic surgery procedures. The present study shows a 2-year result of connective tissue graft associated with LLLT in the treatment of gingival recession defects. METHODS: Forty patients presenting Miller Class I and II gingival recessions were previously treated by: Connective tissue graft (Control group, n = 20) or Connective tissue graft + LLLT (Test group, n = 20)...
November 11, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27814265/the-versatile-subepithelial-connective-tissue-graft-a-literature-update
#8
B V Karthikeyan, Divya Khanna, Kamedh Yashawant Chowdhary, M Lv Prabhuji
Harmony between hard and soft tissue morphologies is essential for form, function, and a good esthetic outlook. Replacement grafts for correction of soft tissue defects around the teeth have become important to periodontal plastic and implant surgical procedures. Among a multitude of surgical techniques and graft materials reported in literature, the subepithelial connective tissue graft (SCTG) has gained wide popularity and acceptance. The purpose of this article is to acquaint clinicians with the current understanding of the versatile SCTG...
November 2016: General Dentistry
https://www.readbyqxmd.com/read/27783851/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-l-prf-part-a-intrabony-defects-furcation-defects-and-periodontal-plastic-surgery-a-systematic-review-and-meta-analysis
#9
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the regenerative potential of leucocyte- and platelet-rich fibrin (L-PRF) during periodontal surgery. MATERIALS AND METHODS: An electronic and hand search were conducted in three databases. Only randomized clinical trials were selected and no follow-up limitation was applied. Pocket depth (PD), clinical attachment level (CAL), bone fill, keratinized tissue width (KTW), recession reduction and root coverage (%) were considered as outcome. When possible, meta-analysis was performed...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27771828/immunoexpression-of-igf1-igf2-and-osteopontin-in-craniofacial-bone-repair-associated-with-autogenous-grafting-in-rat-models-treated-with-alendronate-sodium
#10
Paulo Roberto Camati, Allan Fernando Giovanini, Hugo Eduardo de Miranda Peixoto, Cassiana Majewski Schuanka, Maria Cecília Giacomel, Melissa Rodrigues de Araújo, João César Zielak, Rafaela Scariot, Tatiana Miranda Deliberador
OBJECTIVES: The aim of this study was to verify the likely influence of presurgical administration of low doses of alendronate sodium in craniofacial bone repair and correlate the histological frame found on reparative tissue to the immunohistochemical presence of IGF1, IGF2, and osteopontin (OP). MATERIALS AND METHODS: In total, 120 rats were randomly allocated into four groups: group C (control), group OA (autogenous bone), group B (bisphosphonates), and group OA-B (autogenous bone + bisphosphonates)...
October 22, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27770972/a-novel-multistep-method-for-chondroitin-sulphate-immobilization-and-its-interaction-with-fibroblast-cells
#11
Kadir Ozaltin, Marián Lehocký, Zdenka Kuceková, Petr Humpolíček, Petr Sáha
Polymeric biomaterials are widely used in medical applications owing to their low cost, processability and sufficient toughness. Surface modification by creating a thin film of bioactive agents is promising technique to enhance cellular interactions, regulate the protein adsorption and/or avoid bacterial infections. Polyethylene is one of the most used polymeric biomaterial but its hydrophobic nature impedes its further chemical modifications. Plasma treatment is unique method to increase its hydrophilicity by incorporating hydrophilic oxidative functional groups and tailoring the surface by physical etching...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27770633/polymer-fiber-based-models-of-connective-tissue-repair-and-healing
#12
Nancy M Lee, Cevat Erisken, Thomas Iskratsch, Michael Sheetz, William N Levine, Helen H Lu
Physiologically relevant models of wound healing are essential for understanding the biology of connective tissue repair and healing. They can also be used to identify key cellular processes and matrix characteristics critical for the design of soft tissue grafts. Modeling the various stages of repair post tendon injury, polymer meshes of varying fiber diameter (nano-1 (390 nm) < nano-2 (740 nm) < micro (1420 nm)) were produced. Alignment was also introduced in the nano-2 group to model matrix undergoing biological healing rather than scar formation...
January 2017: Biomaterials
https://www.readbyqxmd.com/read/27766032/a-metabolomic-approach-1-h-hrmas-nmr-spectroscopy-supported-by-histology-to-study-early-post-transplantation-responses-in-islet-transplanted-livers
#13
Kevin Vivot, Malika A Benahmed, Elodie Seyfritz, William Bietiger, Karim Elbayed, Elisa Ruhland, Allan Langlois, Elisa Maillard, Michel Pinget, Nathalie Jeandidier, Jean-Pierre Gies, Izzie-Jacques Namer, Séverine Sigrist, Nathalie Reix
Intrahepatic transplantation of islets requires a lot of islets because more than 50% of the graft is lost during the 24 hours following transplantation. We analyzed, in a rat model, early post-transplantation inflammation using systemic inflammatory markers, or directly in islet-transplanted livers by immunohistochemistry. (1)H HRMAS NMR was employed to investigate metabolic responses associated with the transplantation. Inflammatory markers (Interleukin-6, α2-macroglobulin) are not suitable to follow islet reactions as they are not islet specific...
2016: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/27762645/morphological-features-of-fascia-lata-in-relation-to-fascia-diseases
#14
Sylwia Szotek, Joanna Dawidowicz, Brian Eyden, Natalia Matysiak, Aleksander Czogalla, Grzegorz Dudzik, Anna Leśniewicz, Krzysztof Maksymowicz
Fascia lata is an important element of the fascial system, which forms the continuum of connective tissue throughout the body. This deep fascia envelops the entire thigh and hip area and its main function is to transmit mechanical forces generated by the musculoskeletal system of the lower extremities. Fascia lata is also known as a useful and easily harvested graft material. Despite its crucial role in lower extremity biomechanics and wide-ranging applications in plastic and reconstructive surgery, both the structure of fascia lata and particularly the cells populating this tissue are relatively unexplored and therefore poorly understood...
November 2016: Ultrastructural Pathology
https://www.readbyqxmd.com/read/27761392/periosteum-as-a-lateral-pedicle-graft-for-the-treatment-of-single-tooth-root-recession-a-novel-approach
#15
Avadhesh Kumar, Shalini Kaushal, Neelu Verma, Deepti Chandra
The treatment of gingival recession defects is indicated for esthetic and functional reasons to reduce root sensitivity, to remove muscle pull, to create or augment keratinized tissue, and to prevent disease progression. The presence of sufficient amount of periosteum adjacent to gingival recession defects makes it a suitable graft. The adult human periosteum is a highly vascular connective tissue with immense regenerative potential. It contains fibroblasts, osteogenic progenitor cells, and stem cells as a result of which it has the ability to differentiate into fibroblast, osteoblast, chondrocytes, adipocytes, and skeletal myocytes...
September 2016: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/27755395/an-anatomical-murine-model-of-heterotopic-periorbital-subunit-transplantation
#16
Bowen Gao, Qingxiong Yu, Feng Xie, Lingling Sheng, Xiyuan Mao, Qingfeng Li, Hainan Zhu
BACKGROUND: Conventional reconstructive methods fail to achieve satisfactory results in total eyelid defect cases. Vascularized composite tissue allotransplantation might provide both good appearance and function for these patients. The structure of the eyelid is exceptional because it simultaneously consists of skin, connective tissue, the striated muscle, fiber structure, aponeuroses, and mucosa. Thus, before clinical application of eyelid allotransplantation, more experiments are needed to clarify the impact of ischemia, immunal suppressive agents, and deinnervation effects on these sophisticated structures...
October 13, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27753539/volumetric-stability-of-fresh-frozen-bone-blocks-in-atrophic-posterior-mandible-augmentation
#17
Erick Silva, Emanuela Prado Ferraz, Evandro Carneiro Martins Neto, Liat Chaushu, Gavriel Chaushu, Samuel Porfirio Xavier
The aim of this prospective controlled study present study is to evaluate volumetric changes of newly created bone following reconstruction of the atrophic posterior mandible using FFB. Twenty consecutive patients presenting for reconstruction of posterior mandibular alveolar bone ridge width ≤ 6.0 mm and/or height≤ 6.0 who met all inclusion and exlusion criteria were included. FFB blocks were used. The main outcome variable investigated was bone volume dynamics. Vertical, horizontal and three-dimensional bone gain data was measured from computerized tomography scans...
October 18, 2016: Journal of Oral Implantology
https://www.readbyqxmd.com/read/27751731/use-of-scaffolding-tissue-biografts-to-bolster-vesicourethral-anastomosis-during-salvage-robot-assisted-prostatectomy-reduces-leak-rates-and-catheter-times
#18
Gabriel Ogaya-Pinies, Yash Kadakia, Hariharan Palayapalayam-Ganapathi, Tracey Woodlief, Cathy Jenson, Vipul Patel
BACKGROUND: One of the key factors contributing to morbidity associated with salvage radical prostatectomy is a significant vesicourethral anastomosis (VUA) disruption or postoperative tissue dehiscence in the region of the distal bladder neck that causes a large prolonged urinary leak, perineal pain, and delayed catheter removal. OBJECTIVE: To describe our surgical technique using a urinary bladder extracellular matrix (UB-ECM) scaffold incorporated into the base of the VUA and the distal bladder neck during salvage robot-assisted radical prostatectomy (sRARP) and to assess outcomes and safety...
October 14, 2016: European Urology
https://www.readbyqxmd.com/read/27747637/peri-implant-mucosal-dehiscence-coverage-with-a-modified-semilunar-coronary-positioned-flap-in-posterior-maxilla-a-case-report
#19
Daisuke Ueno, Jayanetti Asiri Jayawardena, Takashi Kurokawa
Soft tissue dehiscence around dental implant has frequently been observed and it may lead to poor oral hygiene, especially around crowns that exhibit contours with prominent convexity. The present case demonstrates a peri-implant mucosal dehiscence coverage with modified semilunar coronary positioned flap (CPF) in #15 and 16. A semilunar partial-thickness incision was performed 7-10 mm apical from the facial gingival margin. Then, intrasulcular partial-thickness incision was tunneled to the semilunar incision...
December 2015: Int J Implant Dent
https://www.readbyqxmd.com/read/27740651/soft-tissue-volume-augmentation-using-connective-tissue-grafts-via-apical-pouch-technical-considerations-and-case-reports
#20
Paul P Lin, Lewis Claman, Hua-Hong Chien
The success of dental implant therapy in the esthetic zone requires not only functional osseointegration but also favorable esthetic results. The greatest challenge in the esthetic zone is to establish harmony, balance, and continuity of gingival form between implant restorations and the adjacent natural teeth. In the esthetic zone, a localized ridge defect or loss of a peri-implant papilla is common and can be corrected via soft tissue augmentation. This case report describes a novel surgical technique using connective tissue grafts via an apical pouch to increase soft tissue volume over an alveolar ridge defect or around natural teeth or implants in the maxillary anterior area...
November 2016: International Journal of Periodontics & Restorative Dentistry
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