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Connective tissue graft

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https://www.readbyqxmd.com/read/28529011/the-effect-of-in-vivo-created-vascularized-neurotube-on-peripheric-nerve-regeneration
#1
Abdul Kerim Yapici, Yalcin Bayram, Hakan Akgun, Recep Gumus, Fatih Zor
INTRODUCTION: Creating vascularized nerve conduits for treatment of nerve gaps have been researched, however, these methods need microsurgical anastomosis thereby complicating the nerve repair process. Thus, the concept of vascularized nerve conduits has not popularized up till now. The aim of this study is to evaluate the effects of vascularized and non-vascularized biological conduits on peripheral nerve regeneration. MATERIAL AND METHODS: Following ethical board approval, 15 Sprague-Dawley rats were used in the study...
May 11, 2017: Injury
https://www.readbyqxmd.com/read/28512278/use-of-collagen-matrix-for-augmentation-of-the-peri-implant-soft-tissue-at-the-time-of-immediate-implant-placement
#2
Gregor-Georg Zafiropoulos, Gordon John
AIM: The aim of this study was to determine the treatment outcome of the use of a porcine monolayer collagen matrix (mCM) to augment peri-implant soft tissue in conjunction with immediate implant placement as an alternative to patient's own connective tissue. MATERIALS AND METHODS: A total of 27 implants were placed immediately in 27 patients (14 males and 13 females, with a mean age of 52.2 years) with simultaneous augmentation of the soft tissue by the use of a mCM...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28510331/isolation-of-ready-to-use-adipose-derived-stem-cell-asc-pellet-for-clinical-applications-and-a-comparative-overview-of-alternate-methods-for-asc-isolation
#3
Edoardo Raposio, Nicolò Bertozzi
Current literature does not offer a standardized method to isolate adipose-derived stem cells (ASCs) for clinical applications and hence clinical studies using ASCs often show inconsistent results. Most of these studies borrow laboratory or benchside-derived protocols, which are complex, time consuming, and involve the use of chemical, animal-derived reagents. In this unit we describe a relatively simple and faster isolation protocol that allows collection of a ready-to-use ASC pellet for clinical application...
May 16, 2017: Current Protocols in Stem Cell Biology
https://www.readbyqxmd.com/read/28494703/globule-leukocytes-and-other-mast-cells-in-the-mouse-intestine
#4
Peter Vogel, Laura Janke, David M Gravano, Meifen Lu, Deepali V Sawant, Dorothy Bush, Shuyu E, Dario A A Vignali, Asha Pillai, Jerold E Rehg
Only 2 major mast cell (MC) subtypes are commonly recognized in the mouse: the large connective tissue mast cells (CTMCs) and the mucosal mast cells (MMCs). Interepithelial mucosal inflammatory cells, most commonly identified as globule leukocytes (GLs), represent a third MC subtype in mice, which we term interepithelial mucosal mast cells (ieMMCs). This term clearly distinguishes ieMMCs from lamina proprial MMCs (lpMMCs) while clearly communicating their common MC lineage. Both lpMMCs and ieMMCs are rare in normal mouse intestinal mucosa, but increased numbers of ieMMCs are seen as part of type 2 immune responses to intestinal helminth infections and in food allergies...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28485490/label-free-relative-quantification-of-secreted-proteins-as-a-non-invasive-method-for-the-quality-control-of-chondrogenesis-in-bioengineered-substitutes-for-cartilage-repair
#5
Christel Henrionnet, Pierre Gillet, Didier Mainard, Jean-Baptiste Vincourt, Astrid Pinzano
Cartilage tissue engineering is making progress but the competing available strategies still leave room for improvement and consensual overviews regarding the best combinations of scaffolds and cell sources are limited by the capacity to compare them directly. In addition, because most strategies involve autologous cell transfer, once these will be optimized, the resulting implants require individual quality control prior to grafting in order to emphasize patient-to-patient differential responsiveness to engineering processes...
May 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28475086/timing-of-soft-tissue-management-around-dental-implants-a-suggested-protocol
#6
Mahdi Kadkhodazadeh, Reza Amid, Mehdi Ekhlasmand Kermani, Mahdieh Mirakhori, Sepanta Hosseinpour
Survival of dental implants depends on several factors; soft tissue (ST) management around dental implants is one of the foremost. Several studies have suggested techniques for ST management around dental implants, but none of them has discussed a suitable timetable for this process. This study aimed to review published articles related to the timing of ST management around dental implants and suggest a customized treatment protocol. A search of the PubMed database was conducted; the search was limited to English-language articles published from January 1995 to July 2015 with available full texts...
May 2017: General Dentistry
https://www.readbyqxmd.com/read/28465795/the-comparison-of-modified-semilunar-technique-in-conjunction-with-connective-tissue-and-subepithelial-connective-tissue-graft-for-root-coverage-a-randomized-controlled-trial
#7
Niloofar Jenabian, Nafiseh Khanjani, Ali Bijani
BACKGROUND: Gingival recession may result in aesthetically unfavourable effects, difficulty in plaque control, increased susceptibility to root caries, and dentin hypersensitivity. OBJECTIVE: The aim of this study was to compare the use of modified semilunar techniques with connective tissue and subepithelial connective tissue grafts (Langer) for denuded root surface coverage. METHODS: In this randomized clinical trial, fourteen localized recessions of Miller class I to II were treated in 5 subjects...
February 2017: Electronic Physician
https://www.readbyqxmd.com/read/28460577/connective-tissue-growth-factor-and-bone-morphogenetic-protein-2-are-induced-following-myocardial-ischemia-in-mice-and-humans
#8
Arkady Rutkovskiy, Julia Sagave, Gabor Czibik, Anton Baysa, Katarina Zihlavnikova Enayati, Vigdis Hillestad, Christen Peder Dahl, Arnt Fiane, Lars Gullestad, Jørgen Gravning, Shakil Ahmed, Håvard Attramadal, Guro Valen, Jarle Vaage
We aimed to study the cardiac expression of bone morphogenetic protein 2, its receptor 1 b, and connective tissue growth factor, factors implicated in cardiac embryogenesis, following ischemia/hypoxia, heart failure, and in remodeling hearts from humans and mice. Biopsies from the left ventricle of patients with end-stage heart failure due to dilated cardiomyopathy or coronary artery disease were compared with donor hearts and biopsies from patients with normal heart function undergoing coronary artery bypass grafting...
May 2, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28452622/histologic-evaluation-of-wound-healing-following-ridge-preservation-with-cortical-cancellous-and-combined-cortico-cancellous-freeze-dried-bone-allograft-a-randomized-controlled-clinical-trial
#9
Randy S Demetter, Blaine G Calahan, Brian L Mealey
BACKGROUND: Cortical and cancellous mineralized freeze-dried bone allografts (FDBA) are available for use in alveolar ridge preservation after tooth extraction. There are currently no data regarding the use of a combination 50/50% cortico-cancellous FDBA compared to a 100% cortical or 100% cancellous FDBA in ridge preservation. The primary objective of this study is to dimensionally and histologically evaluate healing following ridge preservation in non-molar sites using 50/50% cortico-cancellous FDBA versus 100% cortical and 100% cancellous FDBA...
April 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28429535/a-cross-circulated-bicephalic-model-of-head-transplantation
#10
Peng-Wei Li, Xin Zhao, Yun-Long Zhao, Bing-Jian Wang, Yang Song, Zi-Long Shen, Hong-Jun Jiang, Hai Jin, Sergio Canavero, Xiao-Ping Ren
AIMS: A successful cephalosomatic anastomosis ("head transplant") requires, among others, the ability to control long-term immune rejection and avoidance of ischemic events during the head transference phase. We developed a bicephalic model of head transplantation to study these aspects. METHODS AND RESULTS: The thoracic aorta and superior vena cava of a donor rat were anastomosed with the carotid artery and extracorporeal veins of a recipient rat by vascular grafts...
April 21, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28420425/acceleration-of-tendon-bone-healing-of-anterior-cruciate-ligament-graft-using-intermittent-negative-pressure-in-rabbits
#11
Zhengming Sun, Xiaoqing Wang, Ming Ling, Wei Wang, Yanhai Chang, Guang Yang, Xianghui Dong, Shixun Wu, Xueyuan Wu, Bo Yang, Ming Chen
BACKGROUND: The purpose of this study was to test effects of negative pressure on tendon-bone healing after reconstruction of anterior cruciate ligament (ACL) in rabbits. METHODS: Hind legs of 24 New Zealand White rabbits were randomly selected as negative pressure group and the contralateral hind legs as control. Reconstruction of the ACL was done. Joints of the negative pressure side were placed with drainage tubes connecting the micro-negative pressure aspirator...
April 18, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28402358/surgical-treatment-of-a-peripheral-ossifying-fibroma-and-reconstruction-with-a-porcine-collagen-matrix-a-case-report
#12
José González-Serrano, Rosa María López-Pintor, Ignacio Sanz-Sánchez, Víctor Manuel Paredes, Elisabeth Casañas, Lorenzo de Arriba, Gonzalo Hernández Vallejo
A 35-year-old woman was referred to the Department of Oral Medicine and Orofacial Surgery after several recurrences of an ossifying fibroma (OF) that affected the free and attached gingiva of the maxillary right central incisor. Surgery was performed with a complete excision of the lesion together with the surrounding healthy tissue up to the bone. To guide the healing of the anterior esthetic framework and the excised tissues, a porcine collagen matrix as an alternative to connective tissue graft was used...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28402353/peri-implant-soft-tissue-stability-after-single-implant-restorations-using-either-guided-bone-regeneration-or-a-connective-tissue-graft-a-randomized-clinical-trial
#13
Chiara D'Elia, Nicola Baldini, Edoardo Ferrari Cagidiaco, Giacomo Nofri, Cecilia Goracci, Massimo de Sanctis
The purpose of the present study was to compare two different surgical procedures, connective tissue graft and guided bone regeneration, when applied in conjunction with implant placement. Probing pocket depth and the recession depth were recorded at the implant site after crown placement (T₁) and at the 1-year follow-up (T₂), while the keratinized tissue height and the buccal mucosa thickness were recorded at three different time points: at the time of implant surgery (T₀), after crown placement, and at the 1-year follow-up...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28396887/comparison-of-enamel-matrix-derivative-emdogain-and-subepithelial-connective-tissue-graft-for-root-coverage-in-patients-with-multiple-gingival-recession-defects-a-randomized-controlled-clinical-study
#14
Angeliki Alexiou, Ioannis Vouros, Georgios Menexes, Antonis Konstantinidis
OBJECTIVE: The purpose of the present study was to compare the clinical efficiency of enamel matrix derivative (EMD) placed under a coronally advanced flap (CAF; test group), to a connective tissue graft (CTG) placed under a CAF (control group), in patients with multiple recession defects. METHOD AND MATERIALS: Twelve patients with multiple Miller's Class I or II gingival recessions in contralateral quadrants of the maxilla were selected. The primary outcome variable was the change in depth of the buccal recession (REC), at 6 months (T6) after surgery...
2017: Quintessence International
https://www.readbyqxmd.com/read/28370489/volumetric-changes-and-peri-implant-health-at-implant-sites-with-or-without-soft-tissue-grafting-in-the-esthetic-zone-a-retrospective-case-control-study-with-a-5-year-follow-up
#15
Stefan P Bienz, Ronald E Jung, Vitor M Sapata, Christoph H F Hämmerle, Jürg Hüsler, Daniel S Thoma
OBJECTIVES: To evaluate the volumetric changes and peri-implant health at implant sites with and without previous soft tissue grafting over a 5-year observation period. MATERIAL AND METHODS: In 18 partially edentulous patients, dental implants were placed in the esthetic zone (15-25) with simultaneous guided bone regeneration, followed by submerged healing. During the healing phase, eight patients (test) received a subepithelial connective tissue graft, whereas 10 patients (control) did not receive any soft tissue augmentation...
March 29, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28368130/a-novel-technique-in-root-coverage-procedures-the-fibrin-assisted-soft-tissue-promotion-concept
#16
Alexandre-Amir Aalam, Alina Krivitky Aalam, Joseph Choukroun
The goal of periodontal plastic surgery is to correct the soft-tissue deformities associated with the loss of attached and keratinized tissue. A variety of flap manipulations related to the use of subepithelial connective tissue grafts are described with great success in the literature but are linked with morbidity and harvesting-quality issues, inclining clinicians and researchers to find alternatives to such techniques. Advanced platelet-rich fibrin, which is widely used in medicine and oral therapy, represents a newer generation of blood-derived growth factors...
April 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28355311/enhancing-root-eminence-and-papilla-contour-using-single-contoured-subepithelial-connective-tissue-autografts-for-recession-coverage
#17
Donald E Lareau, James E Hinrichs, Georgios A Kotsakis
Current techniques using autogenous soft tissue in periodontal plastic surgery have limitations in the number of teeth that can be treated and may result in suboptimal esthetic results. The innovative use of single, contoured grafts reported in this article overcomes the drawbacks associated with these techniques by more efficient use of available donor tissue. Autogenous tissue is used to graft each individual tooth, leaving the interdental areas uncovered. Multiple teeth-in some cases an entire arch-can be treated in one session, providing consistent and predictable reestablishment of the normal scalloped gingival architecture and convex root eminence...
March 29, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28338039/coronally-advanced-flap-combined-with-connective-tissue-graft-treatment-of-choice-for-root-coverage-following-recession
#18
COMMENT
Ed Madeley, Brett Duane
Data sourcesMedline, The Cochrane Database Trials Register, Embase, supplemented by handsearching of five prominent periodontal journals, references from reviewed papers and contact with experts in the field of mucogingival surgery.Study selectionRandomised controlled trials (RCTs) with or without a split-mouth design, on human patients. RCTs had to compare at least two different surgical interventions on clearly specified recession defects, be over six months in duration and have clearly specified clinical measurements regarding root coverage...
March 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28314534/total-cavopulmonary-connection-with-a-new-bioabsorbable-vascular-graft-first-clinical-experience
#19
Leo A Bockeria, Oleg Svanidze, Alex Kim, Konstantin Shatalov, Vladimir Makarenko, Martijn Cox, Thierry Carrel
OBJECTIVES: To assess safety and clinical performance of a novel bioabsorbable vascular graft in pediatric patients with univentricular cardiac malformation who received surgical correction via an extracardiac cavopulmonary conduit. METHODS: The implanted graft material is designed to attract patient's own cells and proteins, which trigger a cascade of physiological events leading to endogenous tissue restoration. As the graft resorbs progressively after implantation, components of native tissue including collagen, endothelial lining, and capillary blood vessels develop and organize into a natural tissue...
February 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28300879/behavior-study-of-the-doped-castor-bean-polymer-rod-with-bioactive-glass-and-hidroxyapatite-in-mice-femur-medullary-canal
#20
Viviani Teixeira Dos Santos, Gilberto Gonçalves Facco, Hudman Cunha Ortiz, Iandara Schettert da Silva
Purpose To evaluate the polymer doped rods behavior with bioactive glass and hydroxyapatite for possible application as a fracture fixing method. Methods Twenty eight Rattus norvegicus Wistar underwent bone defect for access to the femoral medullary canal and distributed into three experimental groups: group A - doped castor bean polymer with bioactive glass; group B - castor bean polymer and; group C - castor bean polymer doped with bioactive glass and hydroxyapatite. After 15 and 60 evaluation days, the femurs were removed and sent for histology and scanning electron microscopy...
February 2017: Acta Cirúrgica Brasileira
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