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Connective tissue graft

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https://www.readbyqxmd.com/read/29649831/what-is-the-best-way-to-prepare-a-buccal-mucosa-graft-for-urethroplasty-a-histology-based-preliminary-report
#1
André G Cavalcanti, Carlos F Restrepo, Michele Simões, Waldemar S Costa, Francisco J B Sampaio, Diogo B de Souza
PURPOSE: To evaluate the histological characteristics of buccal mucosa samples prepared using different dissection techniques. METHODS: The buccal mucosae harvested from 9 men submitted to a substitution urethroplasty were used in this study. Biopsy specimens of buccal mucosae were grouped according to the macroscopic appearance after dissection: Group 1 - yellowish appearance (minimal dissection), Group 2 - whitish appearance (more aggressive dissection), and Group 3 - translucent appearance (ultra-aggressive dissection)...
April 12, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29649548/spontaneous-atopic-dermatitis-due-to-immune-dysregulation-in-mice-lacking-adamts2-and-14
#2
L Dupont, G Ehx, M Chantry, C Monseur, C Leduc, L Janssen, D Cataldo, M Thiry, C Jerome, J-M Thomassin, B Nusgens, J Dubail, F Baron, A Colige
Since its first description, ADAMTS14 has been considered as an aminoprocollagen peptidase based on its high similarity with ADAMTS3 and ADAMTS2. As its importance for procollagen processing was never experimentally demonstrated in vivo, we generated Adamts14-deficient mice. They are healthy, fertile and display normal aminoprocollagen processing. They were further crossed with Adamts2-deficient mice to evaluate potential functional redundancies between these two highly related enzymes. Initial characterizations made on young Adamts2-Adamts14-deficient animals showed the same phenotype as that of Adamts2-deficient mice, with no further reduction of procollagen processing and no significant aggravation of the structural alterations of collagen fibrils...
April 9, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29603026/wall-thickness-control-in-biotubes-prepared-using-type-c-mold
#3
Takeshi Terazawa, Takanori Nishimura, Tomohiro Mitani, Osamu Ichii, Teppei Ikeda, Keigo Kosenda, Eisuke Tatsumi, Yasuhide Nakayama
A type-C mold based on in-body tissue architecture was previously developed for preparing small-diameter biotube vascular grafts with a 2-mm diameter and approximately 1-mm wall thickness. In this study, the type-C mold was modified for preparing large-diameter biotubes with controlled wall thicknesses. Four types of molds were assembled by inserting silicone center rods (outer diameters 11, 13, 15, 17 mm) into stainless steel cages (inner diameter 19 mm) and surgically embedded in the abdominal subcutaneous pouches of Holstein cows...
March 30, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29600871/treatment-of-a-gingival-injury-from-a-cosmetic-laser-burn-a-case-report
#4
Maha A Bahammam
Gingival depigmentation is a periodontal plastic surgery procedure for the removal of pigmented gingiva. A gingival depigmentation procedure can be accomplished with the use of a laser; however, as described in this case report, laser burns can be associated with such a procedure, and if one occurs it must be subsequently managed. In this case, the patient presented with a large elliptical ulceration at the right maxillary premolar region. The underlying alveolar bone was exposed and the surrounding gingival margins were inflamed...
April 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29587852/repair-of-bone-defects-in-rat-radii-with-a-composite-of-allogeneic-adipose-derived-stem-cells-and-heterogeneous-deproteinized-bone
#5
Jia Liu, Peng Zhou, Yu Long, Chunxia Huang, Danna Chen
BACKGROUND: In the bone tissue engineering domain, seed cells, scaffold and cell-scaffold composites are three focuses. In this study, the feasibility of using allogeneic adipose-derived stem cells(ADSCs) combined with heterogeneous deproteinized bone (HDB) to repair segmental radial defects was investigated by observing the repair of the defect area. METHODS: ADSCs were cultured in vitro, purified, antigen-detected and osteogenic differentiation potency-measured; then, the ADSCs of the third generation were seeded into HDB to prepare an ADSCs-HDB composite partly with osteogenesis induced cells...
March 27, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29582585/low-level-laser-therapy-as-an-adjunct-to-connective-tissue-graft-procedure-in-the-treatment-of-gingival-recession-defects-a-systematic-review-and-meta-analysis
#6
REVIEW
Zohaib Akram, Fahim Vohra, Fawad Javed
OBJECTIVE: The aim of this study was to systematically evaluate the effectiveness of low level laser therapy (LLLT) as an adjunct to connective tissue graft (CTG) procedure for the treatment of gingival recession (GR). MATERIALS AND METHODS: The addressed PICO question was; "In patients with Miller Class I or II recession defects (Population), what is the effect of LLLT as adjunct to CTG (Intervention) in comparison to CTG alone (Comparison) on gingival recession depth (Outcome)" Electronic databases were searched up to December 2017...
March 26, 2018: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/29575589/clinical-and-esthetic-outcome-with-immediate-insertion-and-provisionalization-with-or-without-connective-tissue-grafting-in-presence-of-mucogingival-recessions-a-retrospective-analysis-with-follow-up-between-1-and-8-years
#7
Robert Noelken, Maximilian Moergel, Tobias Pausch, Martin Kunkel, Wilfried Wagner
BACKGROUND: Recessions following immediate implant insertion are frequently reported in the literature. Data regarding implant installation in presence of mucogingival recessions are rare. PURPOSE: This study observes soft tissue level changes following immediate implant insertion and provisionalization of implants with or without connective tissue grafts in the anterior maxilla in patients with initial mucogingival recession within a follow-up period between one and eight years...
March 24, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29569868/what-happens-to-an-acellular-dermal-matrix-after-implantation-in-the-human-body-a-histological-and-electron-microscopic-study
#8
Martin Boháč, Ľuboš Danišovič, Ján Koller, Jana Dragúňová, Ivan Varga
Acellular matrices are used for various purposes and they have been studied extensively for their potential roles in regenerating tissues or organs. The acellular matrix generates physiological cues that mimic the native tissue microenvironment. Acellular dermal matrix (ADM) is a soft connective tissue graft generated by a decellularization process that preserves the intact extracellular skin matrix. Upon implantation, this structure serves as a scaffold for donor-side cells to facilitate subsequent incorporation and revascularization...
January 22, 2018: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/29568176/interdisciplinary-approach-to-enhance-the-esthetics-of-maxillary-anterior-region-using-soft-and-hard-tissue-ridge-augmentation-in-conjunction-with-a-fixed-partial-prosthesis
#9
Shaleen Khetarpal, Ajay Chouksey, Anand Bele, Rahul Vishnoi
Favorable esthetics is one of the most important treatment outcomes in dentistry, and to achieve this, interdisciplinary approaches are often required. Ridge deficiencies can be corrected for both, soft- and hard-tissue discrepancies. To overcome such defects, not only a variety of prosthetic options are at our disposal but also several periodontal plastic surgical techniques are available as well. Various techniques have been described and revised, over the year to correct ridge defects. For enhancing soft-tissue contours in the anterior region, the subepithelial connective tissue graft is the treatment of choice...
January 2018: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29567025/endovascular-thoracic-aortic-repair-in-confirmed-or-suspected-genetically-triggered-thoracic-aortic-dissection
#10
Sherene Shalhub, Kim A Eagle, Federico M Asch, Scott A LeMaire, Dianna M Milewicz
OBJECTIVE: Endovascular repair in patients with connective tissues disorders is not recommended because of concern for repair failure. The aim of this study was to investigate thoracic endovascular aortic repair (TEVAR) outcomes in patients with confirmed or suspected syndromic and nonsyndromic genetically triggered thoracic aortic dissection. METHODS: We analyzed data for patients with descending thoracic aorta (DTA) dissection treated with TEVAR from the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)...
March 19, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29564612/superior-capsular-reconstruction-of-the-shoulder-the-abc-arthroscopic-biceps-chillemi-technique
#11
Claudio Chillemi, Matteo Mantovani, Antonio Gigante
Superior capsular reconstruction (SCR) demonstrated its efficacy as a treatment option available in patients affected with irreparable posterosuperior rotator cuff tears without any signs of arthritis. Originally, the fascia lata autograft was fixed medially to the glenoid (with two or more anchors) and laterally to the greater tuberosity (with a compression double-row technique using four anchors or three transosseous tunnels). Additionally, side-to-side sutures were used to anteriorly and posteriorly connect the graft to the native residual rotator cuff tissue...
March 21, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29556248/growth-of-triple-negative-and-progesterone-positive-breast-cancer-causes-oxidative-stress-and-down-regulates-neuroprotective-transcription-factor-npas4-and-npas4-regulated-genes-in-hippocampal-tissues-of-tumorgraft-mice-an-aging-connection
#12
Anna Kovalchuk, Yaroslav Ilnytskyy, Rocio Rodriguez-Juarez, Amanda Katz, David Sidransky, Bryan Kolb, Olga Kovalchuk
While the refinement of existing and the development of new chemotherapeutic regimens has significantly improved cancer treatment outcomes and patient survival, chemotherapy still causes many persistent side effects. Central nervous system (CNS) toxicity is of particular concern, as cancer patients experience significant deficits in memory, learning, cognition, and decision-making. These chemotherapy-induced cognitive changes are termed chemo brain, and manifest in more than half of cancer survivors. Moreover, recent studies have emerged suggesting that neurocognitive deficits manifest prior to cancer diagnosis and treatment, and thus may be associated with tumor presence, a phenomenon recently termed "tumor brain...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29551861/acellular-dermal-matrix-and-subepithelial-connective-tissue-grafts-for-root-coverage-a-systematic-review
#13
Sarah Ivy Gallagher, Debora Candace Matthews
Background: The aim of this systematic review was to evaluate whether patients with gingival recession would benefit from an acellular dermal matrix graft (ADMG) in ways that are comparable to the gold standard of the subepithelial connective tissue graft (SCTG). Materials and Methods: A systematic review and meta-analysis comparing ADMG to SCTG for the treatment of Miller Class I and II recession defects was conducted according to PRISMA guidelines. PubMed, Excerpta Medica Database, and Cochrane Central Register of Controlled Trials databases were searched up to March 2016 for controlled trials with minimum 6 months duration...
November 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29537650/effect-of-a-connective-tissue-graft-in-combination-with-a-single-flap-approach-in-the-regenerative-treatment-of-intraosseous-defects
#14
Leonardo Trombelli, Anna Simonelli, Luigi Minenna, Giulio Rasperini, Roberto Farina
BACKGROUND: In the attempt to limit the post-surgery increase in buccal gingival recession (bREC), effect of a connective tissue graft (CTG) when combined with a buccal single flap approach (SFA) in the regenerative treatment of intraosseous defects is evaluated. METHODS: Data related to 30 patients with an intraosseous defect treated with a buccal SFA with (SFA+CTG group; n = 15) or without (SFA group; n = 15) placement of a CTG and regenerative treatment were retrospectively derived at three clinical centers...
April 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/29536558/acute-type-a-aortic-dissection-repair-in-younger-patients
#15
Kyokun Uehara, Hitoshi Matsuda, Jiro Matsuo, Yosuke Inoue, Atsushi Omura, Yoshimasa Seike, Hiroaki Sasaki, Junjiro Kobayashi
AIM: To evaluate the surgical outcomes and midterm results of patients under 50 years old with acute type A aortic dissection (AAAD). METHODS: The study population included 51 patients who underwent AAAD repair between 2003 and 2016. Of these 51 patients, 46 (90.1%) were males and 14 (27.5%) had connective tissue disorders. Twenty-five patients (49.0%) had a body mass index >25.0 kg/m2 and two patients were pregnant. Total arch replacement was performed in 39 patients (76...
March 13, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29534133/tissue-dimensional-changes-in-single-tooth-immediate-extraction-implant-placement-in-the-esthetic-zone-a-retrospective-clinical-study
#16
Francesco Amato, Giorgio Polara, Giorgio Alfredo Spedicato
PURPOSE: The aim of this study was to evaluate the buccopalatal volumetric tissue change that occurs following flapless single-tooth immediate extraction placement in the esthetic area and to analyze the role of four different variables. MATERIALS AND METHODS: Patients in need of a single-tooth replacement in the anterior maxillary or mandibular area (premolar to premolar) were recruited for the study. Patients were treated using four different therapeutic modalities: group 1 (healing abutment), group 2 (healing abutment + bone graft), group 3 (provisional restoration), and group 4 (provisional + bone graft)...
March 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29517511/implanted-in-body-tissue-engineered-heart-valve-can-adapt-the-histological-structure-to-the-environment
#17
Yoshiaki Takewa, Hirohito Sumikura, Satoru Kishimoto, Noritsugu Naito, Kei Iizuka, Daichi Akiyama, Ryosuke Iwai, Eisuke Tatsumi, Yasuhide Nakayama
Tissue-engineered heart valves (TEHVs) are expected to be viable grafts. However, it is unknown whether they transit their histological structure after implantation. We developed a novel autologous TEHV (named stent biovalve) for transcatheter implantation, using in-body tissue engineering based on a tissue encapsulation phenomenon. In this study, a time-course histological transition of implanted biovalves was investigated in goats. Three types of stent biovalves were prepared by 2 month embedding of plastic molds mounted with metallic stents, in the subcutaneous spaces...
March 5, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29517410/optimizing-anterior-implant-esthetics-with-a-vascularized-interpositional-periosteal-connective-tissue-graft-for-ridge-augmentation-a-case-report
#18
Cimara Fortes Ferreira, Edival Barreto de Magalhães Junior, Barbara Zini
Achieving excellence in anterior rehabilitations requires close cooperation between the periodontist and the prosthodontist. Many techniques can be used to restore the lost alveolar hard and soft tissues. The more severe the peri-implant defect, the higher the challenge and lower the predictability of the procedure. The present case consists of Seibert class III with mal-aligned implants in the esthetic zone resolved with a cost-modified treatment plan to re-establish esthetics in the anterior maxilla using rotated palatal flap...
March 8, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29508553/biocompatibility-and-osteoconductivity-of-plcl-coated-and-noncoated-xenografts-an-in-vitro-and-preclinical-trial
#19
Yaniv Mayer, Ofir Ginesin, Alaa Khutaba, Eli E Machtei, Hadar Zigdon Giladi
BACKGROUND: Cells, scaffolds, and growth factors are the key components in bone tissue engineering. Scaffold composition, topography, and architecture influence the amount of regenerated bone in the implantation site. The aims of the study were to compare viability and proliferation of mesenchymal stem cells (MSCs) seeded onto two commercial xenografts: Bio-Oss (BO) and bioactive bone bovine (BB). Next, these materials were compared for histomorphometric bone formation in a socket preservation model in rats...
March 6, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29505597/a-novel-ex-vivo-huntington-s-disease-model-for-studying-gabaergic-neurons-and-cell-grafts-by-laser-microdissection
#20
E M André, N Daviaud, L Sindji, J Cayon, R Perrot, C N Montero-Menei
Organotypic brain slice cultures have been recently used to study neurodegenerative disorders such as Parkinson's disease and Huntington's disease (HD). They preserve brain three-dimensional architecture, synaptic connectivity and brain cells microenvironment. Here, we developed an innovative model of Huntington's disease from coronal rat brain slices, that include all the areas involved in the pathology. HD-like neurodegeneration was obtained in only one week, in a single step, during organotypic slice preparation, without the use of neurotoxins...
2018: PloS One
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