Luca Di Lullo, Giovanni Tripepi, Claudio Ronco, Antonio De Pascalis, Vincenzo Barbera, Antonio Granata, Domenico Russo, Biagio Raffaele Di Iorio, Ernesto Paoletti, Maura Ravera, Maria Fusaro, Antonio Bellasi
BACKGROUND: In recent years, novel anticoagulant drugs have been introduced in the clinical armamentarium and have progressively gained momentum. Although their use is increasing among CKD patients, some skepticism about their risk-benefit ratio still persists. We sought to investigate the safety and effectiveness of rivaroxaban in a cohort of moderate-to-advanced CKD patients. METHODS: This observational, retrospective, longitudinal study involved 347 consecutive CKD stage 3b-4 (according to NKF-KDOQI guidelines) patients enrolled from 8 cardiac outpatient clinics between March 2015 and October 2017...
October 2018: Journal of Nephrology