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Acute otitis media in children

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https://www.readbyqxmd.com/read/29322750/use-of-streptococcus-salivarius-k12-to-reduce-the-incidence-pharyngo-tonsillitis-and-acute-otitis-media-in-children-a-retrospective-analysis-in-not-recurrent-pediatric-subjects
#1
Francesco DI Pierro, Paolo Risso, Elena Poggi, Anna Timitilli, Sara Bolloli, Maurizio Bruno, Egidio Caneva, Riccardo Campus, Alessandro Giannattasio
BACKGROUND: Previous trials, performed in subjects affected by recurrent streptococcal pharyngo-tonsillar infection, have shown that the use for 90 days of Streptococcus salivarius K12 (K12), an oral colonizing probiotic producing lantibiotic bacteriocins, reduces the occurrence of streptococcal and viral pharyngitis and acute otitis media (AOM). The aim was to evaluate the role of K12 in reducing the incidence of streptococcal and viral pharyngo-tonsillitis and AOM when administered in two separate trimesters, from October to December and then from April to June, in pediatric subjects with non-recurrent streptococcal infection...
January 11, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/29304178/impact-of-influenza-vaccine-on-childhood-otitis-media-in-taiwan-a-population-based-study
#2
Pei-Wen Wu, Chien-Chia Huang, Wei-Chieh Chao, Chi-Chin Sun, Cheng-Hsun Chiu, Ta-Jen Lee
PURPOSE: Acute otitis media (AOM) is a common infectious disease in children and usually accompanied by a preceding viral respiratory tract infection, especially in the preschool-age population. The study aimed to evaluate impact of influenza vaccine on childhood otitis media. METHODS: This retrospective cohort study included data for 803,592 children (<10 years old) recorded in Taiwan's National Health Insurance Research Database. AOM incidence and tympanostomy tube insertion incidence in each influenza season before and after the introduction of traditional injectable trivalent influenza vaccine (TIV) were compared using the Poisson regression analysis to estimate the incidence rate ratios (IRRs) and 95% confidence intervals (CIs)...
2018: PloS One
https://www.readbyqxmd.com/read/29278616/decreased-aom-with-treatment-failure-following-introduction-of-the-ten-valent-pneumococcal-haemophilus-influenzae-protein-d-conjugate-vaccine
#3
Elias Eythorsson, Birgir Hrafnkelsson, Helga Erlendsdóttir, Sigmar Atli Gudmundsson, Karl G Kristinsson, Ásgeir Haraldsson
BACKGROUND: Acute otitis media non-responsive to antibiotics is most commonly caused by antibiotic-resistant Streptococcus pneumoniae and Haemophilus influenzae. A strategy for treating these infections with parenteral ceftriaxone was adopted at The Children's Hospital Iceland. The 10-valent pneumococcal H. influenzae Protein D-conjugate vaccine (PHiD-CV10) was introduced into the vaccination program in Iceland in 2011. The aim was to study its effect on the incidence of AOM with treatment failure...
December 22, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29273072/monitoring-adherence-to-guidelines-of-antibiotic-use-in-pediatric-pneumonia-the-marea-study
#4
Pasquale Di Pietro, Ornella Della Casa Alberighi, Michela Silvestri, Maria Angela Tosca, Anna Ruocco, Giorgio Conforti, Giovanni A Rossi, Elio Castagnola, Maria Caterina Merlano, Simona Zappettini, Salvatore Renna
BACKGROUND: Children are the most vulnerable population exposed to the use of antibiotics often incorrectly prescribed for the treatment of infections really due to viruses rather than to bacteria. We designed the MAREA study which consisted of two different studies: i) a surveillance study to monitor the safety/efficacy of the antibiotics for the treatment of pneumonia (CAP), pharyngotonsillitis and acute otitis media in children younger than 14 yrs old, living in Liguria, North-West Italy and ii) a pre-/post-interventional study to evaluate the appropriateness of antibiotic prescription for the treatment these infections...
December 22, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29260791/-the-clinical-classification-of-acute-otitis-media-with-special-reference-to-tympanometry
#5
M V Subbotina
We have developed a new clinical classification of acute otitis media (AOM) based on the previously proposed classifications of V.T. Palchun with co-workers (1997) and J. Jeger (1970) in which the letter near the stage of the pathological process roughly corresponds to the type of the tympanogram as follows: stage I (acute tubootitis): A, B, C; stage II (acute catarrhal otitis media): A, B, C; stage III (acute purulent otitis media, perforation stage); stage IV (acute purulent otitis media, post-perforation stage); stage V (resolution of otitis media): A - convalescence or recovery, B1 - exudate present in the tympanic cavity; B2 - persisting perforation; C - block of the auditory tube, O - the development of complications...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29260224/association-of-broad-vs-narrow-spectrum-antibiotics-with-treatment-failure-adverse-events-and-quality-of-life-in-children-with-acute-respiratory-tract-infections
#6
Jeffrey S Gerber, Rachael K Ross, Matthew Bryan, A Russell Localio, Julia E Szymczak, Richard Wasserman, Darlene Barkman, Folasade Odeniyi, Kathryn Conaboy, Louis Bell, Theoklis E Zaoutis, Alexander G Fiks
Importance: Acute respiratory tract infections account for the majority of antibiotic exposure in children, and broad-spectrum antibiotic prescribing for acute respiratory tract infections is increasing. It is not clear whether broad-spectrum treatment is associated with improved outcomes compared with narrow-spectrum treatment. Objective: To compare the effectiveness of broad-spectrum and narrow-spectrum antibiotic treatment for acute respiratory tract infections in children...
December 19, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29258622/nasal-colonization-and-antimicrobial-susceptibility-pattern-of-staphylococcus-aureus-among-pre-school-children-in-ethiopia
#7
Alemayehu Reta, Moges Wubie, Getnet Mekuria
BACKGROUND: Staphylococcus aureus is one of the bacterium that can asymptomatically colonize the human upper respiratory tract (i.e. nose and throat). Carriage of S. aureus, including methicillin resistant S. aureus, is common to children. The aim at this study was to determine the nasal colonization, associated factors and antimicrobial susceptibility patterns of S. aureus isolates among pre-school children in Debre Markos town. METHODS: Institutional-based cross sectional study was conducted...
December 19, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29227464/antibiotic-resistance-of-potential-otopathogens-isolated-from-nasopharyngeal-flora-of-children-with-acute-otitis-media-before-during-and-after-pneumococcal-conjugate-vaccines-implementation
#8
Alexis Rybak, Corinne Levy, Stéphane Bonacorsi, Stéphane Béchet, François Vié le Sage, Annie Elbez, Emmanuelle Varon, Robert Cohen
BACKGROUNDL: To re-evaluate antibiotic strategies for acute otitis media (AOM) in young children, we analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae (Sp), Haemophilus influenzae (Hi) and Moraxella catarrhalis (Mc) isolated from young children with AOM during a 16-year period. METHODS: This cross-sectional study analyzed from 2001 to 2016, the nasopharyngeal carriage of Sp, Hi and Mc of young children with AOM...
December 8, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29201375/children-with-lymphadenitis-associated-with-bacillus-calmette-gu%C3%A3-rin-bcg-vaccination-do-not-experience-more-infections-when-compared-with-bcg-vaccinated-children-without-lymphadenitis-a-three-years-paired-cohort-in-mexico
#9
Enrique Chacon-Cruz, Jorge Luis Arellano-Estrada, Erika Lopatynsky-Reyes, Jorge Alvelais-Palacios, Chandra Becka
Objectives: Vaccination against tuberculosis with live-attenuated Bacillus Calmette-Guérin (BCG) is widely used even though its effectiveness is controversial. BCG-lymphadenitis (BCG-LA) is its most common complication. Some studies have proposed that BCG-LA can be associated with primary immunodeficiencies (PIs). This study's aim is to see whether patients who developed BCG-LA (named as 'LA') developed more infections than BCG-vaccinated children without BCG-LA (named as 'NON-LA'). Methods: From January 2009 to April 2014, 31 LA children were seen at the outpatient clinic of the General Hospital of Tijuana, Mexico...
August 2017: Therapeutic Advances in Vaccines
https://www.readbyqxmd.com/read/29200185/early-vaccine-type-pneumococcal-acute-otitis-media-does-not-predispose-to-subsequent-otitis-when-compared-to-early-acute-otitis-media-due-to-other-bacterial-etiology
#10
Arto A Palmu, Mika Lahdenkari
BACKGROUND: Prevention of acute otitis media (AOM), and especially recurrence and biofilm formation, by pneumococcal conjugate vaccines (PCV) has been hypothesized to be due to prevention of early episodes triggering the vicious cycle. We tested the specific role of vaccine-type pneumococcal AOM in this hypothesis. METHODS: In the phase III randomized, double-blind FinOM Vaccine Trial conducted in 1995-99 children received PCV7 or hepatitis B vaccine as control at 2/4/6/12 months of age and were followed for AOM...
December 1, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29189611/appropriate-and-inappropriate-treatment-of-acute-otitis-media-in-the-pediatric-emergency-department
#11
Sarah Rothman, Jacob Pitaro, Asher Hackett, Eran Kozer, Haim Gavriel, Limor Muallem-Kalmovich, Ephraim Eviatar, Tal Marom
BACKGROUND: Over-treatment of acute otitis media (AOM) with antibiotics is common, and poses a high burden on healthcare systems. METHODS: Records of children 6-36 months of age with AOM visiting a university-affiliated pediatric emergency department (PED) between 2014-2016 were reviewed for the treatment given: watchful waiting (WW) vs. antibiotics. If antibiotics were prescribed, the type and duration were recorded. We evaluated appropriate and inappropriate treatment rates of eligible AOM cases, in respect to the local guidelines, which encourage WW in most mild-moderate cases...
November 16, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29183869/detecting-acute-otitis-media-symptom-episodes-using-a-mobile-app-cohort-study
#12
Annemarijn C Prins-van Ginkel, Marieke LA de Hoog, C Uiterwaal, Henriette A Smit, Patricia Cj Bruijning-Verhagen
BACKGROUND: Population cohort studies are useful to study infectious diseases episodes not attended by health care services, but conventional paper diaries and questionnaires to capture cases are prone to noncompliance and recall bias. Use of smart technology in this setting may improve case finding. OBJECTIVE: The objective of our study was to validate an interactive mobile app for monitoring occurrence of acute infectious diseases episodes in individuals, independent of health care seeking, using acute otitis media (AOM) symptom episodes in infants as a case study...
November 28, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29174076/characteristics-and-progression-of-hearing-loss-in-children-with-down-syndrome
#13
Kathryn L Kreicher, Forest W Weir, Shaun A Nguyen, Ted A Meyer
OBJECTIVES: To evaluate hearing impairment in children with Down syndrome, and to describe the factors that influence the severity of hearing loss or changes in hearing over time. STUDY DESIGN: Using the Audiological and Genetic Database (AudGenDB), audiograms of children with Down syndrome were analyzed retrospectively for type, severity, and laterality of hearing loss, as well as changes over time. Medical charts and imaging results were reviewed to identify factors influencing hearing loss...
November 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29147674/pediatric-otogenic-sigmoid-sinus-thrombosis-case-report-and-literature-reappraisal
#14
Andrea Scherer, Andrew Jea
The purpose of this study was to review our experience with a single case of mastoiditis associated with sigmoid sinus thrombosis and increased intracranial pressure, and to review the experience of others through prior publications. We reviewed a case of a 6-year-old boy with an acute otitis media and mastoiditis, with associated ipsilateral sigmoid sinus and contralateral distal transverse sinus thrombosis. Based on the literature and our own experience, we conclude that most children with dural sinus thrombosis from acute otitis media and mastoiditis, in the setting of increased intracranial pressure, attain a good neurological outcome with a conservative neurosurgical approach...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29113587/streptococcus-pneumoniae-burden-and-nasopharyngeal-inflammation-during-acute-otitis-media
#15
Matthew C Morris, Michael E Pichichero
Streptococcus pneumoniae (Spn) is a common respiratory pathogen and a frequent cause of acute otitis media (AOM) in children. The first step in bacterial pathogenesis of AOM is the establishment of asymptomatic colonization in the nasopharynx. We studied Spn bacterial burden in conjunction with neutrophil recruitment and inflammatory gene transcription and cytokine secretion in samples of nasal wash collected from normal and otitis-prone children during health, viral upper respiratory infection without middle ear involvement (URI) and AOM...
November 2017: Innate Immunity
https://www.readbyqxmd.com/read/29106885/outpatient-management-of-pediatric-acute-mastoiditis
#16
Ahmed Alkhateeb, Francis Morin, Haya Aziz, Mayuri Manogaran, William Guertin, Melanie Duval
OBJECTIVE: Evaluate the Montreal Children's Hospital experience with outpatient management of uncomplicated acute mastoiditis with parenteral antibiotic therapy alone and determine if it is a safe alternative to inpatient management. SUBJECTS AND METHOD: A retrospective review of pediatric patients diagnosed with acute mastoiditis at a tertiary care pediatric hospital between 2013 and 2015 was performed. Patients with syndromes, immunodeficiency, cholesteatoma, chronic otitis media, cochlear implant in the affected ear, or incidental mastoid opacity were excluded...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29106876/early-signs-and-symptoms-of-intracranial-complications-of-otitis-media-in-pediatric-and-adult-patients-a-different-presentation
#17
N A Van der Poel, E van Spronsen, D A Dietz de Loos, F A Ebbens
OBJECTIVES: The aim of this study was to review the clinical presentation and early signs and symptoms of otogenic intracranial complications (OIC) in children and adults. METHODS: retrospective chart review. The medical records of all children and adults admitted in our center with OIC during the period 2008-2017 were reviewed. Data concerning clinical presentation, treatment and outcomes were reviewed and analyzed. RESULTS: We included 47 patients with OIC: 21 children (range 1-13 years) and 26 adults (range 22-71 years)...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29102419/influence-of-pneumococcal-conjugate-vaccines-on-acute-otitis-media-in-japan
#18
Atsushi Sasaki, Masaru Kunimoto, Sachio Takeno, Takahiro Sumiya, Takashi Ishino, Hirotoshi Sugino, Katsuhiro Hirakawa
OBJECTIVE: This study investigated: (i) changes in the incidence of acute otitis media (AOM) following introduction of public funding for free inoculation with 7- and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13, respectively) and (ii) changes in the rate of myringotomies for AOM (MyfA) in children 1year following the publication of the first edition of the clinical practice guidelines for the diagnosis and management of AOM in children in Japan. METHODS: PCV7 was launched on the Japanese market in 2010 and gained public funding in 2011...
November 1, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29097032/-the-infections-of-the-ear
#19
Catherine Nowak, Lei Tanaka, Serge Bobin, Jérôme Nevoux
In front of external otitis in spite of a well-conducted treatment, especially in immunodeficient patient, it is always necessary to look for an osteomyelitis of the skull base that requires an urgent parenteral antibiotic treatment of several weeks. Acute otitis media (AOM) is the most common bacterial infection of the child. In children under 2 years with purulent AOM, antibiotic therapy with amoxicilline is systematic for a period of 8-10 days. After 2 years of age and with mild symptoms of AOM, symptomatic treatment may be justified as first-line treatment...
October 30, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29072655/-the-specific-features-of-the-clinical-course-of-acute-suppurative-otitis-media-of-viral-and-mixed-viral-bacterial-etiology-in-the-children-of-the-preschool-age
#20
E Yu Radtsig, O V Bugaichuk
The objective of the present study was to elucidate the spectrum of the pathogenic agents responsible for the development of acute suppurative otitis media in the children of the preschool age and to reveal the specific clinical features of this disease depending on its etiological factors. The study involved 138 patients (186 ears) of either sex at the age from 1 year to 84 months who presented with acute suppurative otitis media. The following methods were employed for the purpose of the study: analysis of the patients' complaints and the past medical histories, examination of the ENT organs, microbiological (bacteriological and virological) studies of secretion from the tympanic cavity, diagnostic endoscopy of the nasal cavity and nasopharynx, laboratory investigations...
2017: Vestnik Otorinolaringologii
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