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https://www.readbyqxmd.com/read/29344004/perceived-organizational-support-and-moral-distress-among-nurses
#1
Navideh Robaee, Foroozan Atashzadeh-Shoorideh, Tahereh Ashktorab, Ahmadreza Baghestani, Maasoumeh Barkhordari-Sharifabad
Background: Moral distress is prevalent in the health care environment at different levels. Nurses in all roles and positions are exposed to ethically challenging conditions. Development of supportive climates in organizations may drive nurses towards coping moral distress and other related factors. This study aimed at determining the level of perceived organizational support and moral distress among nurses and investigating the relationship between the two variables. Methods: This was a correlational-descriptive study...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29343158/placebo-effects-in-traumatic-brain-injury
#2
Ginger Polich, Mary Alexis Iaccarino, Ted J Kaptchuk, Leon Morales-Quezada, Ross Zafonte
In recent years, several randomized controlled trials evaluating pharmaceutical treatments for traumatic brain injury (TBI) have failed to demonstrate efficacy over placebo, with both active and placebo arms improving at comparable rates. These findings could be viewed in opposing ways, suggesting on the one hand failure of the tested outcome, but representing on the other, evidence of robust placebo effects in TBI. In this article, we examine several of the primary psychological processes driving placebo effects (verbal suggestion, cognitive re-framing, interpersonal interactions, conditioning, therapeutic alliance, anxiety reduction) as well as placebo neurobiology (top-down cortical regulation, reward system activation, dopaminergic and serotonergic neurotransmission)...
January 17, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29342466/deep-vein-thrombosis-a-rare-cause-of-acute-testicular-pain-case-report-literature-review
#3
Adrián Amador Robayna, Jonathan Rodríguez Talavera, Begoña Ballesta Martínez, Javier Falcón Barroso, Almudena Carrión Valencia, Nuria Orribo Morales, Melania Santacruz Pérez, Jesús Monllor Gisbert
INTRODUCTION: Thrombosis is defined as the formation of a clot in a blood vessel that obstructs the flow of blood to the peripheral tissues. The incidence of thromboembolic disease ranges from 0.7 to 1.2% within urology. CASE REPORT: A 40-year-old warehouse worker male presented to the emergency department with worsening of a month's lasting scrotal pain. Physical examination showed the presence of an enlarged and painful left testicle with no other findings. Right testicle, penis and abdominal examination showed no abnormalities whatsoever...
January 17, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29342285/serial-participation-and-the-ethics-of-phase-1-healthy-volunteer-research
#4
Rebecca L Walker, Marci D Cottingham, Jill A Fisher
Phase 1 healthy volunteer clinical trials-which financially compensate subjects in tests of drug toxicity levels and side effects-appear to place pressure on each joint of the moral framework justifying research. In this article, we review concerns about phase 1 trials as they have been framed in the bioethics literature, including undue inducement and coercion, unjust exploitation, and worries about compromised data validity. We then revisit these concerns in light of the lived experiences of serial participants who are income-dependent on phase 1 trials...
January 12, 2018: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/29340847/comparative-analysis-of-aneurysm-volume-by-different-methods-based-on-angiography-and-computed-tomography-angiography
#5
Víctor Hugo Escobar-de la Garma, Marco Zenteno, Felipe Padilla-Vázquez, Daniel San-Juan, Aurelio Cerón-Morales
Endovascular treatment and prognosis of intracranial aneurysms are based on size and volume, which demand more accurate neuroimaging techniques. Aneurysm volume calculation is important to choose endovascular treatment modalities and packing density calculation. Of all these methods, it remains unknown which one is the most accurate to calculate aneurysm volume. The objective of this study is to compare the accuracy of three angiography-based versus three tomographic-based methods which calculate aneurysm volume...
January 16, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29338965/quality-of-life-and-clinical-characterization-of-patients-with-vernal-keratoconjunctivitis-in-a-pediatric-population-in-colombia
#6
C M Gómez-Henao, C I Herrera-Morales, R Ramírez-Giraldo, R Cardona-Villa
Vernal keratoconjunctivitis is one of the most serious ocular allergies that have the potential to induce large ocular morbidity and significant visual changes affecting the quality of life of these individuals. METHODOLOGY: This study was conducted in two phases. The first phase consisted of the clinical characterization of 32 patients from the Clinical Allergology center of the I.P.S. Universitaria from July 2014 to February 2015. A retrospective analysis of medical records was performed...
January 12, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29336069/an-examination-of-the-interaction-between-morality-and-self-control-in-offending-a-study-of-differences-between-girls-and-boys
#7
Anna-Karin Ivert, Frida Andersson, Robert Svensson, Lieven J R Pauwels, Marie Torstensson Levander
BACKGROUND: There is a well-documented gender difference in offending, with evidence that boys, on average, are more involved in crime than girls. Opinions differ, however, on whether the causes of crime apply to girls and boys similarly. AIMS: Our aim is to explore crime propensity in boys and girls. Our research questions were (1) are there differences between boys and girls in moral values and self-control; (2) are these attributes similarly correlated with offending among girls and boys; and (3) is any interaction effect between morality and self-control identical for girls and boys...
January 16, 2018: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/29330304/efficient-prion-disease-transmission-through-common-environmental-materials
#8
Sandra Pritzkow, Rodrigo Morales, Adam Lyon, Luis Concha-Marambio, Akihiko Urayama, Claudio Soto
Prion diseases are a group of fatal neurodegenerative diseases associated with a protein-based infectious agent, termed prion. Compelling evidence suggests that natural transmission of prion diseases is mediated by environmental contamination with infectious prions. We hypothesized that several natural and man-made materials, commonly found in the environments of wild and captive animals, can bind prions and may act as vectors for disease transmission. To test our hypothesis, we exposed surfaces composed of various common environmental materials (i...
January 12, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29322579/the-employee-retention-triad-in-healthcare-exploring-relationships-among-organizational-justice-affective-commitment-and-turnover-intention
#9
Tyrone A Perreira, Whitney Berta, Monique Hebert
BACKGROUND: Turnover in healthcare is a serious concern, as it is contributes to the global nursing shortage and is associated with declines in quality of care, patient safety, and patient outcomes. Turnover also impacts care teams and is associated with decreased staff cohesion and morale. PURPOSE: The purpose of this study is to increase understanding of the relationships between organizational justice, affective commitment and turnover intention in healthcare...
January 10, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29316683/biological-and-proteolytic-variation-in-the-venom-of-crotalus-scutulatus-scutulatus-from-mexico
#10
Miguel Borja, Edgar Neri-Castro, Gamaliel Castañeda-Gaytán, Jason L Strickland, Christopher L Parkinson, Juan Castañeda-Gaytán, Roberto Ponce-López, Bruno Lomonte, Alejandro Olvera-Rodríguez, Alejandro Alagón, Rebeca Pérez-Morales
Rattlesnake venoms may be classified according to the presence/absence and relative abundance of the neurotoxic phospholipases A 2 s (PLA 2 s), such as Mojave toxin, and snake venom metalloproteinases (SVMPs). In Mexico, studies to determine venom variation in Mojave Rattlesnakes (Crotalus scutulatus scutulatus) are limited and little is known about the biological and proteolytic activities in this species. Tissue (34) and venom (29) samples were obtained from C. s. scutulatus from different locations within their distribution in Mexico...
January 8, 2018: Toxins
https://www.readbyqxmd.com/read/29314177/assessment-of-the-antinociceptive-and-ulcerogenic-activity-of-the-tapentadol-diclofenac-combination-in-rodents
#11
Juan R Zapata-Morales, Ángel J Alonso-Castro, Vinicio Granado-Soto, Sergio Sánchez-Enriquez, Mario A Isiordia-Espinoza
Preclinical Research & Development The objective of the present study was to evaluate the tapentadol-diclofenac combination in three dose-ratios in the mouse acetic acid-induced visceral pain and their ulcerogenic activity on the stomachal mucous. Dose-response curves were generated for tapentadol, diclofenac, and their combination in the acetic acid-induced writhing test in mice. Moreover, the stomachs of animals were surgically removal and gastrointestinal ulcerogenic action of the combination was assessed...
January 3, 2018: Drug Development Research
https://www.readbyqxmd.com/read/29310512/moxifloxacin-versus-levofloxacin-for-antibacterial-prophylaxis-in-acute-leukemia-patients
#12
Pauline Lee, Randall W Knoebel, Jennifer Pisano, Natasha N Pettit
Objective The primary endpoint of this study was to determine the incidence of febrile neutropenia among patients receiving either moxifloxacin or levofloxacin for antibacterial prophylaxis. Secondary endpoints were number of documented infections and in-hospital mortality in patients who develop febrile neutropenia. Methods A single-center retrospective cohort analysis at a large tertiary care academic medical center was conducted. This study included adult acute leukemia patients (age ≥18 years old) who received inpatient antibacterial prophylaxis (moxifloxacin or levofloxacin) from 1 July 2012 to 1 October 2014...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29306123/improving-biodegradability-of-soil-washing-effluents-using-anodic-oxidation
#13
María Belén Carboneras, Pablo Cañizares, Manuel Andrés Rodrigo, José Villaseñor, Francisco Jesus Fernandez-Morales
In this work, a combination of electrochemical and biological technologies is proposed to remove clopyralid from Soil Washing Effluents (SWE). Firstly, soil washing was carried out to extract clopyralid from soil. After that, four different anodes-Ir-MMO, Ru-MMO, pSi-BDD and Carbon Felt (CF)-were evaluated in order to increase the biodegradability of the SWE. CF was selected because was the only one able to transform the pesticide to a more biodegradable compounds without completely mineralizing it. Finally, biological oxidation tests were performed to determine the aerobic biodegradability of the SWE generated...
December 21, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29304845/testing-decision-making-competency-of-schizophrenia-participants-in-clinical-trials-a-meta-analysis-and-meta-regression
#14
Sorin Hostiuc, Mugurel Constantin Rusu, Ionut Negoi, Eduard Drima
BACKGROUND: The process of assessing the decision-making capacity of potential subjects before their inclusion in clinical trials is a legal requirement and a moral obligation, as it is essential for respecting their autonomy. This issue is especially important in psychiatry patients (such as those diagnosed with schizophrenia). The primary purpose of this article was to evaluate the degree of impairment in each dimension of decision-making capacity in schizophrenia patients compared to non-mentally-ill controls, as quantified by the (MacCAT-CR) instrument...
January 5, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29304156/engaging-in-extreme-activism-in-support-of-others-political-struggles-the-role-of-politically-motivated-fusion-with-out-groups
#15
Jonas R Kunst, Beverly Boos, Sasha Y Kimel, Milan Obaidi, Maor Shani, Lotte Thomsen
Humans are a coalitional, parochial species. Yet, extreme actions of solidarity are sometimes taken for distant or unrelated groups. What motivates people to become solidary with groups to which they do not belong originally? Here, we demonstrate that such distant solidarity can occur when the perceived treatment of an out-group clashes with one's political beliefs (e.g., for Leftists, oppressive occupation of the out-group) and that it is driven by fusion (or a feeling of oneness) with distant others with whom one does not share any common social category such as nationality, ethnicity or religion...
2018: PloS One
https://www.readbyqxmd.com/read/29300372/adaptation-and-validation-of-the-acmg-amp-variant-classification-framework-for-myh7-associated-inherited-cardiomyopathies-recommendations-by-clingen-s-inherited-cardiomyopathy-expert-panel
#16
Melissa A Kelly, Colleen Caleshu, Ana Morales, Jillian Buchan, Zena Wolf, Steven M Harrison, Stuart Cook, Mitchell W Dillon, John Garcia, Eden Haverfield, Jan D H Jongbloed, Daniela Macaya, Arjun Manrai, Kate Orland, Gabriele Richard, Katherine Spoonamore, Matthew Thomas, Kate Thomson, Lisa M Vincent, Roddy Walsh, Hugh Watkins, Nicola Whiffin, Jodie Ingles, J Peter van Tintelen, Christopher Semsarian, James S Ware, Ray Hershberger, Birgit Funke
PurposeIntegrating genomic sequencing in clinical care requires standardization of variant interpretation practices. The Clinical Genome Resource has established expert panels to adapt the American College of Medical Genetics and Genomics/Association for Molecular Pathology classification framework for specific genes and diseases. The Cardiomyopathy Expert Panel selected MYH7, a key contributor to inherited cardiomyopathies, as a pilot gene to develop a broadly applicable approach.MethodsExpert revisions were tested with 60 variants using a structured double review by pairs of clinical and diagnostic laboratory experts...
January 4, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29290081/b-type-natriuretic-peptide-and-other-risk-factors-for-predicting-postoperative-atrial-fibrillation-after-thoracic-surgery
#17
Zhenye Pu, Xiaotong Qi, Tao Xue, Zhiyong Liu, Yanhu Wu
BACKGROUND:  Postoperative atrial fibrillation (POAF) is associated with increased morality rate, prolonged hospitalization, and reduced long-term survival after surgery. Thus, prediction of POAF is important to assess surgical risk and provide prophylaxis. METHODS:  It was a prospective study of 207 consecutive patients who underwent a routine preoperative laboratory testing before thoracic surgery from October 2016 to May 2017. Comprehensive data were collected...
December 31, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29289866/validation-of-6%C3%A2-min-step-test-and-4-m-gait-speed-in-children-a-randomized-cross-over-study
#18
Gregory Reychler, Nicolas Audag, Sophie Dewulf, Natalia Morales Mestre, Gilles Caty
INTRODUCTION: Even if 6-min walking test (6MWT) is the criterion standard for functional exercise performance evaluation, new field tests are required as practical alternative. This study aims to establish the validity of the 6-min step test (6MST) and the 4-m gait speed (4MGS) in children. METHOD: It is a randomized cross-over trial. Sixty one healthy children from 6 to 12 years were recruited. 6MWT, 6MST and 4MGS were randomly performed on three consecutive days...
December 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29287839/advantages-of-early-diagnosis-of-diabetic-neuropathy-in-the-prevention-of-diabetic-foot-ulcers
#19
Irene Sanz-Corbalán, José Luis Lázaro-Martínez, Esther García-Morales, Raúl Molines-Barroso, Francisco Álvaro-Afonso, Yolanda García-Álvarez
AIMS: to evaluate the utility of the sudomotor function test (SFT) as a clinical tool in the Risk Stratification System of diabetic patients and to demonstrate the earlier detection of the risk of developing diabetic foot ulcers (DFU) compared to the standard clinical tests. METHODS: prospective follow-up study on 263 patients enrolled consecutively over 3.5 years. Diabetic patients without active DFU were classified according to the International Working Group Risk Stratification System (RSS) and categorized according to the results of the Semmes-Wenstein Monofilament (SWM) and biothesiometer measurements or the SFT...
December 26, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29286011/prevalence-of-zoonotic-and-non-zoonotic-genotypes-of-giardia-intestinalis-in-cats-a-systematic-review-and-meta-analysis
#20
Sebastián Ramírez-Ocampo, Juan David Cotte-Alzate, Ángel A Escobedo, Alfonso J Rodríguez-Morales
There are no meta-analyses specifically describing the prevalence of zoonotic and non-zoonotic genotypes of Giardia intestinalis in cats, which would be useful in defining the importance of cats as a source of zoonotic transmission. We performed a systematic review of the literature in three databases (PubMed, Scopus and SciELO) to assess the proportion of cats that were infected with specific G. intestinalis genotypes. A meta-analysis using a random effects model was performed to calculate the pooled prevalence and 95% confidence intervals (95%CI)...
December 1, 2017: Le Infezioni in Medicina
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