Jaganmay Sarkar, Shreya Dhepe, Amrita Shivalkar, Rutuja Kuhikar, Shruti More, Vijay Bhaskar Reddy Konala, Paresh Bhanushali, Amit Khanna
We developed a well-characterized human induced pluripotent stem cell (iPSC) line obtained from healthy individuals' peripheral blood mononuclear cells (PBMC). The PBMCs were primed and reprogrammed using a non-integrating sendai viral vector, and the iPSC lines demonstrated complete differentiation capacity. This line, YBLi004-A, is available and registered in the human pluripotent stem cell registry. The line's legitimacy was validated using pluripotent marker expression, in vitro differentiation into three germ layers (ectoderm, mesoderm, and endoderm), karyotyping, and STR analysis...
March 24, 2024: Stem Cell Research