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Thoracic aneurysm

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https://www.readbyqxmd.com/read/28932555/does-bioglue-contribute-to-anastomotic-pseudoaneurysm-after-thoracic-aortic-surgery
#1
Wei-Guo Ma, Bulat A Ziganshin, Chang-Fa Guo, Mohammad A Zafar, Richard S Sieller, Maryann Tranquilli, John A Elefteriades
BACKGROUND: Although bovine serum albumin-glutaraldehyde glue (BioGlue®) has been successfully used as a hemostatic adjunct in aortic surgical procedures, there are reports that it may lead to anastomotic pseudoaneurysm formation. We seek to examine if the use of BioGlue is associated with a high incidence of anastomotic pseudoaneurysm formation following surgical repair of thoracic aortic disease. METHODS: We reviewed the medical records and follow-up computed tomography (CT) scans of patients from 2001 to 2015 in whom BioGlue was used during surgical repair of thoracic aortic disease to detect postoperative anastomotic pseudoaneurysm formation...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28932545/effects-of-preemptive-cerebrospinal-fluid-drainage-on-spinal-cord-protection-during-thoracic-endovascular-aortic-repair
#2
Seungjun Song, Suk-Won Song, Tae Hoon Kim, Kwang-Hun Lee, Kyung-Jong Yoo
BACKGROUND: Spinal cord injury (SCI) is reported to occur in 3-12% of thoracic endovascular aortic repair (TEVAR) cases, but is a potentially preventable complication of TEVAR for thoracoabdominal pathologies. Although many strategies have been devised to reduce the incidence of SCI, the effectiveness of prophylactic cerebrospinal fluid drainage (CSFD) and left subclavian artery (LSA) revascularization remains controversial. METHODS: From 2012 to 2014, 162 patients underwent TEVAR at a single institution...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28925047/voxel-by-voxel-4d-flow-mri-based-assessment-of-regional-reverse-flow-in-the-aorta
#3
Xin Shen, Susanne Schnell, Alex J Barker, Kenichiro Suwa, Lingzi Tashakkor, Kelly Jarvis, James C Carr, Jeremy D Collins, Shyam Prabhakaran, Michael Markl
BACKGROUND: Complex and reverse flow in the aorta has been implicated in aneurysm development and stroke via retrograde embolization. PURPOSE: To evaluate global and regional differences between standard 2D plane-based and volumetric voxel-based quantification of regional forward/reverse flow, and reverse flow fraction (RFF) in the aorta. STUDY TYPE: Retrospective. SUBJECTS: In all, 35 subjects: 10 healthy controls (age: 57 ± 7 years, nine male), nine patients without aortic valve regurgitation (AR) (age: 63 ± 10 years, seven male), six patients with mild AR (age: 66 ± 6 years, five male), and 10 with moderate or severe AR (age: 60 ± 16 years, eight male)...
September 18, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28921013/spinal-cord-injury-as-a-complication-of-thoracic-endovascular-aneurysm-repair
#4
REVIEW
Taijiro Sueda, Shinya Takahashi
OBJECTIVE: Spinal cord ischemia (SCI) is a devastating complication of thoracic aortic aneurysm repair in the era of thoracic endovascular aneurysm repair (TEVAR). This review aims to clarify the causes of SCI during TEVAR and to propose ways that it may be prevented. METHODS AND RESULTS: We performed an extensive literature search of SCI during TEVAR. Based on the existing literature, we examined the anatomy of the anterior spinal cord artery, which supplies blood to the anterior aspect of the spinal cord, and discuss reported effective ways to prevent SCI during TEVAR, including augmentation of arterial blood pressure and drainage of cerebrospinal fluid...
September 18, 2017: Surgery Today
https://www.readbyqxmd.com/read/28920634/outcomes-analysis-of-stent-graft-repair-for-thoracic-aorta-emergencies
#5
Mourad Boufi, Florent Vernet, Bianca Dona, Olivier Hartung, Anderson D Loundou, Martine Haccoun, Marc Leone, Yves S Alimi
BACKGROUND: This study aimed to identify patient, pathology and procedure-related factors affecting perioperative and mid-term mortality of thoracic aorta emergencies. METHODS: Between 2007 and 2014, patients treated emergently with thoracic stent-graft were retrospectively reviewed. Variables analyzed were: age, renal insufficiency, shock, cardiac arrest, transfer status, pathology, debranching procedures, operation duration, vascular access and European System for Cardiac Operative Risk Evaluation (EuroSCORE)...
December 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28912006/predictors-of-late-aortic-intervention-in-patients-with-medically-treated-type-b-aortic-dissection
#6
Samuel I Schwartz, Christopher Durham, W Darrin Clouse, Virendra I Patel, R Todd Lancaster, Richard P Cambria, Mark F Conrad
BACKGROUND: Patients with medically managed type B aortic dissection (TBAD) have a high incidence of aorta-related complications over time. Whereas early thoracic endovascular aortic repair (TEVAR) to seal the entry tear can promote aortic remodeling and prevent late aneurysm formation, there are sparse data as to which patients will benefit from such therapy. The goal of this study was to identify clinical and anatomic factors that are associated with the need for subsequent aortic intervention in patients who present with uncomplicated TBAD...
September 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28910688/aortic-fibromuscular-dysplasia-complicated-by-dissection-a-case-report-and-review-of-literature
#7
Takashi Tasaki, Kazuhito Hatanaka, Mari Kirishima, Shun Ohnishi, Yuko Goto, Ikumi Kitazono, Tsubasa Hiraki, Sohsuke Yamada, Michiyo Higashi, Akihide Tanimoto
Fibromuscular dysplasia (FMD) is an idiopathic, segmental, nonatherosclerotic, non-inflammatory vascular disease, which is often complicated by the occurrence of dissection. Although it is known to occur in all arteries, aortic involvement is relatively rare. To date, 33 cases of aortic FMD have been reported in available English literature, among which only three cases have been complicated by the occurrence of dissection. We describe the case of a 40-year-old woman diagnosed with aortic FMD complicated by the occurrence of a type A aortic dissection...
August 9, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28905268/fluid-and-biomechanical-analysis-of-ascending-thoracic-aorta-aneurysm-with-concomitant-aortic-insufficiency
#8
F Condemi, S Campisi, M Viallon, T Troalen, G Xuexin, A J Barker, M Markl, P Croisille, O Trabelsi, C Cavinato, A Duprey, S Avril
We present a comprehensive and original framework for the biomechanical analysis of patients affected by ascending thoracic aorta aneurysm and aortic insufficiency. Our aim is to obtain crucial indications about the role played by deranged hemodynamics on the ATAAs risk of rupture. Computational fluid dynamics analysis was performed using patient-specific geometries and boundary conditions derived from 4D MRI. Blood flow helicity and wall shear stress descriptors were assessed. A bulge inflation test was carried out in vitro on the 4 ATAAs after surgical repair...
September 13, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28903623/endovascular-stenting-of-mid-aortic-syndrome-due-to-takayasu-arteritis
#9
Ali Dogan, Kenan Sever, Emrah Ozdemir, Denyan Mansuroglu, Nuri Kurtoglu
Introduction-patients: Takayasu arteritis may involve various parts of the aorta and its major branches. It leads to occlusive or aneurysmal disease of the vessel. It can be treated either with surgery or percutaneous intervention. We report a successful endovascular treatment of stenosis of the descending thoracic and abdominal aorta in a 19-year-old female. Methods-results-conclusions: Self-expandable nitinol stent was deployed and adequate opening of the aorta was obtained in this patient. Long-term durability of endovascular approach is a matter of debate...
September 13, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28902661/giant-thoracoabdominal-aortic-aneurysm
#10
Luca Di Marco, Domenico Attinà, Davide Pacini
: Aneurysms of the descending thoracic and thoracoabdominal aorta are life-threatening conditions. All aneurysms which have not yet had an indication for the treatment need regular follow-up to prevent rupture or dissection. We present a case of a patient with a giant aneurysm of the thoracoabdominal aorta who was denied both surgery and endovascular treatment.
September 11, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28901506/whole-exome-sequencing-identifies-fbn1-mutations-in-two-patients-with-early%C3%A2-onset-type-b-aortic-dissection
#11
Qian Han, Wenwen Zhang, Changjian Liu, Min Zhou, Feng Ran, Long Yi, Xitai Sun, Zhao Liu
The etiology of thoracic aortic aneurysm and dissection (TAAD) is complex and heterogeneous. Emerging evidence has demonstrated that genetic causes may be a consideration in early‑onset TAAD. Owing to overlapping clinical phenotypes and the genetic heterogeneity of TAAD, it is challenging for clinicians to make a molecular diagnosis of TAAD, particularly in those who present with non‑specific syndromic features. In order to identify the causative mutation in two young patients with acute type B aortic dissection without syndromic features, whole exome sequencing (WES) was performed in the present study...
August 31, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28898997/angiotensin-ii-infusion-into-apoe-mice-a-model-for-aortic-dissection-rather-than-abdominal-aortic-aneurysm
#12
Bram Trachet, Lydia Aslanidou, Alessandra Piersigilli, Rodrigo A Fraga-Silva, Jessica Sordet-Dessimoz, Pablo Villanueva-Perez, Marco F M Stampanoni, Nikolaos Stergiopulos, Patrick Segers
Aims: Angiotensin II-infused ApoE-/- mice are a popular mouse model for preclinical aneurysm research. Here, we provide insight in the often-reported but seldom-explained variability in shape of dissecting aneurysms in these mice. Methods and results: N = 45 excised aortas were scanned ex vivo with phase-contrast X-ray tomographic microscopy. Micro-ruptures were detected near the ostium of celiac and mesenteric arteries in 8/11 mice that were sacrificed after 3 days of angiotensin II-infusion...
August 1, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28893704/late-complication-after-thoracic-endovascular-aortic-repair-what-is-a-role-of-an-open-surgical-conversion
#13
Lazar Davidovic, Milos Sladojevic, Igor Koncar, Miroslav Markovic, Tulga Ulus, Nikola Ilic, Marko Dragas, Vladimir Cvetic, Zoran Rancic
BACKGROUND: We would like to evaluate causes of Thoracic Endovascular Aortic Repair (TEVAR) failure and conversion to open surgery (COS) in high volume vascular center for open surgery, with low volume TEVAR procedures. METHODS: A total of 8 patients (6 males, mean aged 55.14 years) underwent COS after TEVAR. The indications for conversion to open surgery, intraoperative strategy, as well as early postoperative and mid follow-up results were analyzed. RESULTS: The indications for COS were persistent proximal type I endoleak with progressive aneurysm enlargement in two patients, endoleak type III in one patient, progressive aneurysm enlargement with no endoleak in one patient, stent graft migration in two patients, secondary aorto-esophageal fistula in one patient, secondary aorto-esophageal and aorto-bronchial fistula in one patient, as well as distal progression of the aneurysmal disease in 2 patient...
September 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28893088/double-locus-lymphoplasmacytic-aortitis
#14
Szabolcs Miskolczi, Mary N Sheppard, Gábor Bogáts, Laszlo Göbölös
Thoracic aortic aneurysm is an indication for major cardiovascular operative procedures. The etiology is usually hypertension and/or atherosclerotic disease; reaching a certain diameter often results in acute aortic syndrome. Immunoglobulin G4-related aortitis, characterized by lymphoplasmacytic vascular tunica media induration without well-defined underlying infectious or autoimmune systemic causes, is uncommon. Histological similarity to immunoglobulin G4 disease in other organs suggests that this aortitis might be a manifestation of systemic pathology...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28890066/ascending-aorta-endovascular-repair-of-a-symptomatic-penetrating-atherosclerotic-ulcer-with-a-custom-made-endo-graft
#15
Theodoros Kratimenos, Nikolaos G Baikoussis, Dimitrios Tomais, Michalis Argiriou
BACKGROUND: Thoracic endovascular aortic repair (TEVAR) has become lately the procedure of choice in the treatment of most pathologies of descending thoracic aorta. Aortic arch aneurysms also came to be treated by TEVAR with various hybrid techniques or custom made scalloped/fenestrated stent-grafts. Zone 0; ascending TEVAR is more challenging than TEVAR of the descending thoracic aorta or aortic arch because of the more complex pathology, hemodynamics, and anatomy. Ascending TEVAR can be a lifesaving treatment in selected high surgical risk patients...
September 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887263/changes-in-geometry-and-cardiac-deformation-of-the-thoracic-aorta-after-thoracic-endovascular-aortic-repair-tevar
#16
Kelsey Hirotsu, Ga-Young Suh, Jason T Lee, Michael D Dake, Dominik Fleischmann, Christopher P Cheng
BACKGROUND: TEVAR has dramatically expanded treatment options for patients with thoracic aortic pathology. The interaction between endografts and the dynamic anatomy of the thoracic aorta is not well characterized for repetitive physiologic stressors and subsequent issues related to long-term durability. Through 3D modeling we sought to quantify cardiac-induced aortic deformation before and after TEVAR to assess the impact of endografts on dynamic aortic anatomy. METHODS: Eight patients with acute (n = 4) or chronic (n = 3) Type B dissections, or chronic arch aneurysm (n = 1), underwent TEVAR with a single (n = 5) or multiple (n = 3) Gore C-TAG(s)...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887261/stenting-of-subclavian-artery-true-and-false-aneurysms-a-systematic-review
#17
REVIEW
Anastasios Maskanakis, Nikolaos Patelis, Demetrios Moris, Diamantis I Tsilimigras, Dimitrios Schizas, Maria Diakomi, Chris Bakoyiannis, Sotirios Georgopoulos, Chris Klonaris, Theodoros Liakakos
BACKGROUND: Aneurysms of the subclavian artery are usually the result of trauma, atherosclerosis or thoracic outlet syndrome. Until the 90s, open surgical repair was considered the only therapeutic choice, exhibiting high complication rates. Since the first report of endovascular repair of subclavian aneurysms in 1991, promising results have been published. OBJECTIVES: To summarize all available data on SA true and false aneurysm stenting in order to reach conclusions regarding morbidity, mortality and other procedure-related characteristics...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28886442/four-new-cases-of-pediatric-thoracic-aortic-aneurysm-taa-with-review-of-the-molecular-genetic-basis-utilizing-the-newly-published-consensus-nomenclature
#18
Shriprasad Deshpande, Adina Alazraki, Nasim Khoshnam, Diana Kantarovich, Pooya Hoseinzadeh, Camden Hebson, Ajay Bhatia, Lauren Schaffer, Elana Maccou, Bahig M Shehata
The majority of thoracic aortic aneurysms (TAA) in the pediatric population are due to post repair etiology (iatrogenic). Although rare, underlying inheritable disease and congenital cardiac anomalies represent the most common non-iatrogenic cause of TAA among patients in this age group (1-21 years of age). Herein, we present a case series of 9aortic aneurysms with varying underlying etiology. We discuss the molecular genetic basis of these syndromes in conjunction with the radiological findings and histological description utilizing the newly published consensus criteria article...
July 27, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28884233/in-vivo-strain-analysis-of-dilated-ascending-thoracic-aorta-by-ecg-gated-ct-angiographic-imaging
#19
Salvatore Pasta, Valentina Agnese, Marzio Di Giuseppe, Giovanni Gentile, Giuseppe M Raffa, Diego Bellavia, Michele Pilato
Accurate assessment of aortic extensibility is a requisite first step for elucidating the pathophysiology of an ascending thoracic aortic aneurysm (ATAA). This study aimed to develop a framework for the in vivo evaluation of the full-field distribution of the aortic wall strain by imaging analysis of electrocardiographic- (ECG) gated thoracic data of 34 patients with ATAA. Seven healthy controls (i.e., non-aneurysmal aorta) from patients who underwent ECG-gated CT angiography for coronary artery diseases were included for comparison...
September 7, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28883797/genetic-bases-of-bicuspid-aortic-valve-the-contribution-of-traditional-and-high-throughput-sequencing-approaches-on-research-and-diagnosis
#20
REVIEW
Betti Giusti, Elena Sticchi, Rosina De Cario, Alberto Magi, Stefano Nistri, Guglielmina Pepe
Bicuspid aortic valve (BAV) is a common (0.5-2.0% of general population) congenital heart defect with increased prevalence of aortic dilatation and dissection. BAV has an autosomal dominant inheritance with reduced penetrance and variable expressivity. BAV has been described as an isolated trait or associated with syndromic conditions [e.g., Marfan Marfan syndrome or Loeys-Dietz syndrome (MFS, LDS)]. Identification of a syndromic condition in a BAV patient is clinically relevant to personalize aortic surgery indication...
2017: Frontiers in Physiology
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