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https://www.readbyqxmd.com/read/28643219/triple-antithrombotic-therapy-in-atrial-fibrillation-patients-undergoing-pci-a-fading-role
#1
Dimitrios Alexopoulos, Panagiotis Vlachakis, John Lekakis
Triple antithrombotic therapy (TAT), consisting of aspirin, a P2Y12 receptor antagonist and oral anticoagulant (OAC) medication has been considered as an 'unavoidable' strategy for a 1-12 months for atrial fibrillation (AF) patients post acute coronary syndrome or percutaneous coronary angioplasty with stenting. However, TAT has rather poorly been adopted in real life practice, mainly because of an accompanying increased bleeding potential and lack of definitive results of randomized clinical trials. Several registries, meta-analyses and small randomized trials have so far provided the base of guidelines recommendations...
June 22, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28641848/the-use-of-embolic-protection-devices-is-associated-with-a-lower-stroke-and-death-rate-after-carotid-stenting
#2
Christoph Knappich, Andreas Kuehnl, Pavlos Tsantilas, Sofie Schmid, Thorben Breitkreuz, Michael Kallmayer, Alexander Zimmermann, Hans-Henning Eckstein
OBJECTIVES: The aim of this study was to analyze the association between intraprocedural and periprocedural variables and in-hospital stroke or death rate after carotid artery stenting. BACKGROUND: In Germany, all open surgical and endovascular procedures on the extracranial carotid artery must be documented in a statutory nationwide quality assurance database. METHODS: A total of 13,086 carotid artery stenting procedures for asymptomatic (63...
June 26, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28640320/molecular-signature-of-coronary-stent-thrombosis-oxidative-stress-and-innate-immunity-cells
#3
Judit Cubedo, Ana Blasco, Teresa Padro, Ilaria Ramaiola, Oriol Juan-Babot, Javier Goicolea, José Antonio Fernández-Díaz, Juan Francisco Oteo, Lina Badimon
The clinical impact of in-stent thrombosis is high because it is associated with high mortality and 20 % of the patients suffer a recurrent event within the two following years. The aim of this study was to characterise the morphologic and proteomic profile of in-stent thrombi (IST) in comparison to thrombi developed on native coronary arteries (CT) to identify a differential molecular signature. The study included 45 patients with ST-elevation-myocardial-infarction (STEMI) treated by primary-percutaneous-intervention and thrombus aspiration: 21 had IST and 24 had CT...
June 22, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28636774/reducing-the-risk-of-post-ercp-pancreatitis
#4
REVIEW
B Joseph Elmunzer
Pancreatitis is the most common and potentially devastating complication of endoscopic retrograde cholangiopancreatography (ERCP), resulting in significant morbidity, occasional mortality, and increased healthcare expenditures. Accordingly, the prevention of post-ERCP pancreatitis (PEP) remains a major clinical and research priority. Strategies to reduce the incidence of PEP include thoughtful patient selection, appropriate risk-stratification, sound procedural technique, prophylactic pancreatic stent placement, and pharmacoprevention...
June 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28636091/biodegradable-stents-in-the-treatment-of-benign-biliary-strictures-does-one-size-fit-all
#5
Aydin Seref Koksal, Ahmet Tarik Eminler, Erkan Parlak
We read the article entitled 'Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report on clinical use in patients' by Siiki et al with great interest (1). The authors successfully treated two patients with benign biliary strictures, possibly due to choledocholithiasis, with endoscopic insertion of polydioxanone biodegradable biliary stents. They reported that the treatment was uneventful and the stents were completely dissolved between 3 and 6 months without leaving a sequela in the bile ducts...
June 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28623378/carotid-stenting-in-neuroradiology-a%C3%A2-short-journey-from-the-past-to-current-debates
#6
REVIEW
Joachim Berkefeld, Marlies Wagner, Richard du Mesnil
After a period of stagnation due to negative results of randomized trials for patients with symptomatic stenosis, the relevance of carotid artery stenting (CAS) is increasing again. CAS has become an important and evidence-based part of interventional stroke treatment. Our ability to manage acute recanalization of carotid occlusions and other niche indications properly led some skeptical neurologists to trust in carotid intervention for elective cases as well. The evolution of CAS from initial euphoria to more realistic views under consideration of trial results and guidelines is reviewed...
June 16, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28622426/experimental-study-on-the-friction-effect-of-plastic-stent-for-biliary-stone-fragmentation-with-video
#7
Chang-Il Kwon, Gwangil Kim, Seok Jeong, Sung Hoon Choi, Kwang Hyun Ko, Don Haeng Lee, Joo Young Cho, Sung Pyo Hong
OBJECTIVES: In patients with irretrievable or intractable bile duct stone, temporary insertion of plastic stent (PS) followed by further ERCP or surgery has been recommended as a "bridge" therapy. However, the exact mechanism of stone fragmentation has not been discovered. The aim of this study was to evaluate whether PS shape can facilitate stone fragmentation. METHODS: Using a new in vitro bile flow phantom model, we compared the friction effect among the three different PS groups (straight PS group; double pigtail-shaped PS group, and screw-shaped PS group) and the control group...
June 16, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28621639/outcome-of-the-double-j-stent-placement-in-pediatric-kidney-transplant-a-single-center-experience
#8
Hakan Sözen, Onur Özen, Kibriya Fidan, Oğuz Söylemezoğlu, Aydın Dalgıç
OBJECTIVES: Double J stent placement at kidney transplant may reduce stenosis or leakage complication rates. However, placement may also increase risk for early urinary tract infection (ie, < 3 mo after transplant). In children, the usefulness of double J stent placement is not well defined. MATERIALS AND METHODS: We analyzed retrospective data from children who received transplants at the Gazi University Transplantation Center and Pediatric Nephrology (Ankara, Turkey) for outcomes related to double J stents...
June 16, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28621638/urologic-complications-after-renal-transplant-a-single-center-experience
#9
Hakan Sözen, Metin Onaran, Onur Özen, Aydın Dalgıç
OBJECTIVES: Urologic complications after kidney transplant are associated with significant morbidity, mortality, and prolonged hospital stay. An intervention or second surgical procedure is frequently required. Here, we report urologic complications in adult kidney recipients. MATERIALS AND METHODS: Since 2006, 171 adult kidney transplant procedures have been performed at the Gazi University Transplantation Center (Ankara, Turkey). Among these patients, there were 65 adult female (38%) and 106 adult male (62%) recipients...
June 16, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28606906/a-randomised-comparison-of-conventional-versus-intentional-strategy-in-patients-with-high-risk-prediction-of-side-branch-occlusion-in-coronary-bifurcation-intervention-rationale-and-design-of-the-cit-resolve-trial
#10
Dong Zhang, Dong Yin, Chenxi Song, Chengang Zhu, Ajay J Kirtane, Bo Xu, Kefei Dou
INTRODUCTION: The intentional strategy (aggressive side branch (SB) protection strategy: elective two-stent strategy or jailed balloon technique) is thought to be associated with lower SB occlusion rate than conventional strategy (provisional two-stent strategy or jailed wire technique). However, most previous studies showed comparable outcomes between the two strategies, probably due to no risk classification of SB occlusion when enrolling patients. There is still no randomised trial compared the intentional and conventional strategy when treating bifurcation lesions with high risk of SB occlusion...
June 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28603588/transcervical-access-reversal-of-flow-and-mesh-covered-stents-new-options-in-the-armamentarium-of-carotid-artery-stenting
#11
REVIEW
Kosmas I Paraskevas, Frank J Veith
In the last 25 years, the very existence of carotid artery stenting (CAS) has been threatened on a number of occasions. The initial disappointing results that even lead to the discontinuation of an early randomized controlled trial have improved considerably with time. Novel devices, advanced stent and equipment technology, alternative types of access and several types of filters/emboli protecting devices have been reported to reduce stroke/death rates during/after CAS and improve CAS outcomes. The present review will provide a description of the various technology advances in the field that aim to reduce stroke and death rates associated with CAS...
May 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28603515/factors-influencing-decision-making-for-carotid-endarterectomy-versus-stenting-in-the-very-elderly
#12
REVIEW
Sung Hyuk Heo, Cheryl D Bushnell
As the population ages worldwide, the number of elderly patients with carotid stenosis is also increasing. There have been many large clinical trials comparing carotid endarterectomy (CAE) versus stenting, but the inclusion criteria (i.e., symptomatic or asymptomatic), stenting methods (i.e., protection device), and primary end point (i.e., the definition of myocardial infarction and follow-up period) were different between trials. Therefore, the interpretation of those results is difficult and requires attention...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28602632/brachial-ankle-pulse-wave-velocity-as-a-predictor-of-silent-cerebral-embolism-after-carotid-artery-stenting
#13
Tomoaki Murakami, Hajime Nakamura, Takeo Nishida, Tomohiko Ozaki, Katsunori Asai, Tomoki Kidani, Yoshinori Kadono, Manabu Sakaguchi, Toshiki Yoshimine, Haruhiko Kishima
BACKGROUND: In neuroendovascular therapy, the effect of arterial stiffness on postprocedural cerebral thromboembolism is unknown. In this observational study, we examined the relationship between cerebral thromboembolism after carotid artery stenting and arterial stiffness. METHODS: From April 2015 to February 2017, we enrolled consecutive patients undergoing scheduled carotid artery stenting in our institution. In all patients, preprocedural brachial-ankle pulse wave velocity was used to assess arterial stiffness, whereas the number of new cerebral ischemic lesions on diffusion-weighted magnetic resonance imaging was assessed after treatment...
June 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28596038/predictors-of-30-day-postoperative-major-adverse-clinical-events-after-carotid-artery-stenting-an-analysis-of-the-procedure-targeted-american-college-of-surgeons-national-surgical-quality-improvement-program
#14
Kyla M Bennett, John R Hoch, John E Scarborough
BACKGROUND: Information about carotid artery stenting (CAS) is largely derived from clinical trials, consensus statements, and outcomes comparisons between CAS and carotid endarterectomy. Given these limitations, the goal of this study was to identify risk factors for adverse outcomes after CAS among hospitals participating in the CAS-targeted American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP). METHODS: Our study sample consisted of patients from the 2012 to 2015 CAS-targeted ACS NSQIP data set...
June 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28595342/letter-commentary-carotid-artery-angioplasty-and-stenting-without-distal-embolic-protection-devices
#15
Mandy J Binning, Erol Veznedaroglu
No abstract text is available yet for this article.
June 8, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28594797/-single-centre-experience-with-implantation-of-the-e-vita-open-plus-hybrid-stent-graft
#16
B N Kozlov, D S Panfilov, V V Saushkin, M S Kuznetsov, G G Nasrashvili, A V Andriianova, V M Shipulin
Hybrid technologies appear to have been gaining ground in surgery of the thoracic aorta. The present study was aimed at assessing the immediate clinical outcomes of surgical treatment of diseases of the thoracic aorta by means of the 'E-vita open plus' hybrid stent graft. The 'E-vita open plus' hybrid stent graft was implanted to 18 patients. All operations were carried out in the conditions of moderate hypothermia. The brain was protected by unilateral cerebral perfusion through the brachiocephalic trunk. The duration of artificial circulation averagely amounted to 265...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28580611/isolated-pulmonary-regurgitation-causes-decreased-right-ventricular-longitudinal-function-and-compensatory-increased-septal%C3%A2-pumping-in-a-porcine-model
#17
Sascha Kopic, Sigurdur S Stephensen, Einar Heiberg, Håkan Arheden, Philipp Bonhoeffer, Mads Ersbøll, Niels Vejlstrup, Lars Søndergaard, Marcus Carlsson
AIM: Longitudinal ventricular contraction is a parameter of cardiac performance with predictive power. Right ventricular longitudinal function is impaired in patients with free pulmonary regurgitation (PR) following corrective surgery for Tetralogy of Fallot (TOF). It remains unclear whether this is a consequence of the surgical repair, or whether it is inherent to PR. The aim of this study was to assess the relationship between longitudinal, lateral and septal pumping in a porcine model of isolated PR...
June 5, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28574040/-use-of-a-filtering-protective-device-during-angioplasty-and-stenting-of-the-brachiocephalic-trunk
#18
V N Tsygankov, A M Frantsevich
The authors carried out a pilot study aimed at assessing the possibility and efficacy of using filtering systems for protection of cerebral arteries from distal embolism during angioplasty and stenting of the brachiocephalic trunk. A total of five patients presenting with lesions of the brachiocephalic trunk underwent 5 roentgenoendovascular interventions with the use of the filtering protective device Spider FX. Angiographic and clinical success was achieved in 100% of cases. Particles of debris were obtained from the protective device in all cases...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28571187/study-of-short-and-intermediate-term-clinical-outcomes-of-patients-with-protected-and-unprotected-lmca-stenting
#19
Pooja M Vyas, Jayesh S Prajapati, Sibasis S Sahoo, Iva Vipul Patel, Jagjeet K Deshmukh, Chirag Patel, Roopesh Singhal
INTRODUCTION: Significant unprotected Left Main Coronary Artery (LMCA) disease is detected in 5%-7% of cases undergoing Coronary Angiography (CAG). Present guidelines have revealed the significance of anatomical location in left main artery stenosis and syntax scores for determination of Major Adverse Cardiac Events (MACE). Debate still persists over the best treatment regarding outcomes of Coronary Artery Bypass Grafting (CABG) and LMCA stenting for patients with LMCA disease. AIM: Aim of the study was to evaluate short and intermediate term clinical outcomes of Percutaneous Coronary Intervention (PCI) in LMCA disease in respect to mortality, Cerebrovascular Accidents (CVA), reinfarction, stent restenosis and need for repeat target lesion revascularization...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28567361/unexpected-evolution-of-a-non-stenotic-lesion-in-the-left-main-coronary-artery-of-a-patient-with-non-st-segment-elevation-myocardial-infarction
#20
Alexandru Florin Ispas, Lionel Mangin, Alexandru Paziuc, Loic Belle
A 72-year-old man was referred to our catheterization laboratory 48 hours after a non-ST-segment elevation myocardial infarction. His medical history included coronary artery disease (CAD) (percutaneous coronary intervention of the right coronary artery and chronic total occlusion of the circumflex artery), atrial fibrillation (AF), and chronic kidney disease. An electrocardiogram showed a pre-existent left bundle-branch block and the patient's maximum cardiac troponin concentration was 8.64 µg/L (upper limit of normal: 0...
June 2017: Cardiovascular Diagnosis and Therapy
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