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Delayed ejaculation

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https://www.readbyqxmd.com/read/29785530/azoospermia-and-embryo-morphokinetics-testicular-sperm-derived-embryos-exhibit-delays-in-early-cell-cycle-events-and-increased-arrest-prior-to-compaction
#1
Nina Desai, Pavinder Gill, Nicholas N Tadros, Jeffrey M Goldberg, Edmund Sabanegh, Tommaso Falcone
PURPOSE: Sperm play an essential role in embryonic genome activation and embryonic progression to blastocyst. In the present work, we focus on development of embryos created as a result of ICSI with testicular or epididymal sperm from azoospermic males and compare this to outcomes from normospermic males. The objective of this study was to determine if sperm origin influences clinical outcomes, the kinetics of embryo development, or the incidence of cleavage anomalies and multinucleation...
May 21, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29755571/plasma-oxytocin-level-and-sexual-dysfunction-in-depressed-women-treated-by-either-fluoxetine-or-citalopram-a-pilot-clinical-trial
#2
Mohammad Abbasinazari, Mona Heidari-Kord, Azadeh Mazaheri-Meybodi, Azadeh Eshraghi, Nima Bayati
Sexual dysfunction is a common cause of selective serotonin reuptake inhibitor (SSRI) withdrawal. Various studies indicate that decreased oxytocin is involved as a mechanism of delayed ejaculation induced by SSRIs. The aim of the present pilot study was to evaluate and compare sexual dysfunction and oxytocin levels in women being treated with either fluoxetine or citalopram. Thirty-nine women with the diagnosis of major depressive disorder were enrolled in the study. A baseline blood sample was collected and each participant was given either fluoxetine 20 mg/d or citalopram 20 mg/d...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29704917/testosterone-and-sexual-function-in-men
#3
REVIEW
Giulia Rastrelli, Giovanni Corona, Mario Maggi
Testosterone (T) is deeply involved in every step of the male sexual response. However, the occurrence of sexual disorders cannot be automatically related to a decline in T levels. In fact, this relationship is complicated by organic, relational and psychological factors, which can independently impair sexual function. For example, it is recognized that erectile dysfunction (ED) can result from vascular damage as well as from low levels of T. T therapy (TTh) can improve sexual function but meta-analyses show that it improves erectile function only in men with ED and overt hypogonadism...
June 2018: Maturitas
https://www.readbyqxmd.com/read/29523489/male-sexual-quality-of-life-is-maintained-satisfactorily-throughout-life-in-the-amazon-rainforest
#4
Thiago Teixeira, Maira Nazima, Jorge Hallak
INTRODUCTION: The Amazon Rainforest is a cradle of biodiversity, where different ethnic groups have specific sexual habits. AIMS: To define the average sexual quality of life of Amazonian men 18 to 69 years old, evaluate the influence of aging on their sexual function, and calculate the prevalence of premature ejaculation, delayed ejaculation, and hypoactive sexual desire disorder. METHODS: A cross-sectional quantitative probability sample study was performed with a demographically representative population (N = 385), with data collected privately at participants' houses, including men who had been sexually active for a minimum of 6 months...
June 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29493183/sexual-complications-of-penile-frature-in-men-who-have-sex-with-men
#5
Rodrigo Barros, Gabriel Lacerda, Alex Schul, Paulo Ornellas, Leandro Koifman, Luciano A Favorito
OBJECTIVES: Evaluate the demographic data, etiology, operative findings and results of surgical treatment of penile fracture (PF) in men who have sex with men(MSM) with emphasis on sexual complications. MATERIALS AND METHODS: We studied 216 patients underwent surgical correction of PF at our hospital. Patients self-identified as MSM were followed for at least 6 months. Demographic data, presentation, operative findings, International Index of Erection Function - 5 (IIEF-5) and the Premature Ejaculation Diagnostic Tool...
March 1, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29463441/perineal-ultrasound-a-review-in-the-context-of-ejaculatory-dysfunction
#6
REVIEW
Connor M Forbes, Ryan Flannigan, Darius A Paduch
BACKGROUND: Ejaculation consists of the emission of semen from seminal vesicles and prostate, followed by expulsion. Ejaculatory dysfunction may take several forms including premature ejaculation, delayed or anejaculation, retrograde ejaculation, and painful ejaculation. Ejaculation is what we can see whereas orgasm is what we feel. The presence of ejaculate does not indicate the ability to experience orgasm. Hence, for the purpose of this work we consider orgasm and ejaculation as 2 separate neurobiological phenomena...
February 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29453817/endocrine-and-psychological-aspects-of-sexual-dysfunction-in-klinefelter-patients
#7
A Ferlin, R Selice, S Angelini, M Di Grazia, N Caretta, F Cavalieri, A Di Mambro, C Foresta
Klinefelter syndrome is a frequent cause of hypogonadism, but despite hundreds of publications on different aspects of Klinefelter syndrome, only a few studies dealt with sexual dysfunction. In particular, testosterone is critical for various aspects of sexual response, but its role on sexuality in Klinefelter syndrome patients is debatable and no studies have evaluated the efficacy of testosterone treatment on sexual dysfunction in these subjects. Furthermore, the impact of psychological and relational aspects on sexual function of Klinefelter syndrome subjects is poorly defined...
February 17, 2018: Andrology
https://www.readbyqxmd.com/read/29441202/pulse-wave-doppler-ultrasound-of-testicular-arteries-and-their-relationship-with-semen-characteristics-in-healthy-bulls
#8
Alessia Gloria, Augusto Carluccio, Laura Wegher, Domenico Robbe, Claudio Valorz, Alberto Contri
Background: Semen evaluation is used to estimate the testicular function. In bulls, the spermatozoa present in the ejaculate are the result of a process that begun more than 2 mo earlier, bequeathing a delayed depiction of the actual function of the testis. Since testis vascularization might be critical for the gonad function, selected pulse wave Doppler ultrasound parameters were assessed in this study, for instance the peak systolic velocity, the end diastolic velocity and the resistive index of the testicular artery along the spermatic cord, the marginal portion of the testicular artery and the intratesticular branches of the testicular artery both in healthy adult and young bulls...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29432875/new-tools-to-measure-ejaculatory-latency-arousal-to-ejaculation-time-interval-and-erection-to-ejaculation-time-interval-a-pilot-study
#9
Gajanan S Bhat, Anuradha Shastry
OBJECTIVE: The present study aimed to evaluate the proposed novel tools, namely, arousal to ejaculation time interval (AETI) and erection to ejaculation time interval (EETI), and to measure ejaculatory latency during different types of sexual encounters in a pilot study. MATERIALS AND METHODS: The study period was from September 2016 to December 2016. After obtaining informed consent and institutional review board approval, the medical practitioners without any comorbidity and who volunteered to participate were asked to report their self-assessed AETI and EETI during a sexual activity...
February 9, 2018: Urology
https://www.readbyqxmd.com/read/29299903/delayed-ejaculation-pathophysiology-diagnosis-and-treatment
#10
REVIEW
Ibrahim A Abdel-Hamid, Omar I Ali
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29284824/clozapine-induced-delayed-ejaculation
#11
Soumitra Das, Adesh Kumar Agrawal
No abstract text is available yet for this article.
November 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29031313/routes-to-diagnosis-for-men-with-prostate-cancer-men-s-cultural-beliefs-about-how-changes-to-their-bodies-and-symptoms-influence-help-seeking-actions-a-narrative-review-of-the-literature
#12
REVIEW
Michelle King-Okoye, Anne Arber, Sara Faithfull
PURPOSE: To examine the findings of existing studies in relation to men's cultural beliefs about changes to their bodies relevant to prostate cancer and how these affect interpretation of bodily changes and help-seeking actions. METHOD: We undertook a narrative review of studies conducted from 2004 to 2017 in 6 databases that highlighted men's beliefs and help-seeking actions for bodily changes suggestive of prostate cancer. RESULTS: Eighteen (18) studies reflecting men from various ethnicities and nationalities were included...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28904397/study-of-the-link-between-dopamine-transporter-gene-polymorphisms-and-response-to-paroxetin-and-escitalopram-in-patients-with-lifelong-premature-ejaculation
#13
T K Eltonsi, T M Tawfik, L A Rashed, S F GamalEl Din, M A Mahmoud
We evaluated the role of dopamine (DA) transporter gene polymorphism in lifelong premature ejaculation (LPE) and its role in determining the response to paroxetine and escitalopram. Eighty consecutive patients and controls were recruited. Sixty of them suffered from LPE. They were divided into two equal groups. One group received paroxetine 20 mg daily for 3 months and the other one received ecistalopram 20 mg daily for 3 months. Their wives were instructed to measure the intra-vaginal ejaculation latency time using stopwatch...
November 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28807505/delayed-ejaculation-and-associated-complaints-relationship-to-ejaculation-times-and-serum-testosterone-levels
#14
RANDOMIZED CONTROLLED TRIAL
Abraham Morgentaler, Paula Polzer, Stanley Althof, Alexander Bolyakov, Craig Donatucci, Xiao Ni, Ankur B Patel, Shehzad Basaria
BACKGROUND: Although delayed ejaculation (DE) is typically characterized as a persistently longer than anticipated or desired time to ejaculation (or orgasm) during sexual activity, a timing-based definition of DE and its association with serum testosterone has not been established in a large cohort. AIM: To examine in an observational study estimated intravaginal ejaculatory latency time (IELT) and masturbatory ejaculation latency time (MELT) in men self-reporting DE, assess the association of IELT and MELT with serum testosterone levels, and determine whether correlation with demographic and sexual parameters exist...
September 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28679197/total-phallic-reconstruction-after-penile-amputation-for-donkey-bite-case-report-and-review-of-the-literature
#15
REVIEW
Francesco De Luca, Giulio Garaffa, Angela Maurizi, Emy Manzi, Carlo De Dominicis, David Ralph
There are very few reported cases of traumatic amputation of the male genitalia due to animal bite. The management involves thorough washout of the wounds, debridement, antibiotic prophylaxis, tetanus and rabies immunization followed by immediate reconstruction or primary wound closure with delayed reconstruction, when immediate reconstruction is not feasible. When immediate reconstruction is not feasible, long-term good functional and cosmetic results are still possible in the majority of cases by performing total phallic reconstruction...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28630352/structural-complexity-and-molecular-heterogeneity-of-a-butterfly-ejaculate-reflect-a-complex-history-of-selection
#16
Camille Meslin, Tamara S Cherwin, Melissa S Plakke, Jason Hill, Brandon S Small, Breanna J Goetz, Christopher W Wheat, Nathan I Morehouse, Nathan L Clark
Male ejaculates are often structurally complex, and this complexity is likely to influence key reproductive interactions between males and females. However, despite its potential evolutionary significance, the molecular underpinnings of ejaculate structural complexity have received little empirical attention. To address this knowledge gap, we sought to understand the biochemical and functional properties of the structurally complex ejaculates of Pieris rapae butterflies. Males in this species produce large ejaculates called spermatophores composed of an outer envelope, an inner matrix, and a bolus of sperm...
July 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28540176/the-effect-of-8-oh-dpat-and-dapoxetine-on-gene-expression-in-the-brain-of-male-rats-during-ejaculation
#17
Xijun Qin, Xiaojun Ma, Dongping Tu, Zuliang Luo, Jie Huang, Changming Mo
The 5-HT1A receptor agonist 8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT) promotes ejaculation of male rats, whereas dapoxetine delays this process. However, the gene expression profile of the brain at ejaculation following administrationof these two compounds has not been fully elucidated. In the present study, a transcriptomic BodyMap was generated by conducting mRNA-Seq on brain samples of male Sprague-Dawley rats. The study included four groups: pre-copulatory control (CK) group, ejaculation (EJ) group, 0...
May 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28501545/betamethasone-causes-intergenerational-reproductive-impairment-in-male-rats
#18
Cibele Dos Santos Borges, Taina Louise Pacheco, Katiussia Pinho da Silva, Fábio Henrique Fernandes, Mary Gregory, André Sampaio Pupo, Daisy Maria F Salvadori, Daniel G Cyr, Wilma De G Kempinas
Prenatal betamethasone (BM) exposure in rats negatively impacts sperm quality and male fertility. Studies have shown that BM can cause multi-generational effects on the pituitary-adrenal-axis of rats. The objective of this study was to assess the reproductive development and fertility of male rats (F2) whose fathers (F1) were exposed to BM (0.1mg/kg) on gestational days 12, 13, 18 and 19. In F2 rats, there was a significant reduction in body weights of the BM-treated group at PND 1 as well as delayed onset of puberty, and decreases in FSH levels, Leydig cell volume, sperm number and motility, seminal vesicle contractility and ejaculated volume...
August 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28474611/patient-reported-ejaculatory-function-and-satisfaction-in-men-with-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#19
Min Chul Cho, Jung Kwon Kim, Sang Hoon Song, Sung Yong Cho, Sang Wook Lee, Soo Woong Kim, Jae-Seung Paick
This study aimed to investigate perceived ejaculatory function/satisfaction before treatment for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) and to identify associations between specific categories of ejaculatory dysfunctions (EjDs) and LUTS. A total of 1574 treatment-naïve men with LUTS/BPH were included in this study. All patients underwent routine evaluation for LUTS/BPH including the International Index of Erectile Function and a 5-item questionnaire developed to assess ejaculatory volume/force/pain/satisfaction/latency time...
January 2018: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28465683/chronic-administration-of-tadalafil-improves-the-symptoms-of-patients-with-amicrobic-magi-an-open-study
#20
Sandro La Vignera, Rosita A Condorelli, Laura M Mongioi, Aldo E Calogero
Aim of this study was to evaluate the effects of pharmacological treatment with Tadalafil 5 mg daily on symptoms and quality of sperm parameters in selected patients with amicrobic MAGI (male accessory gland inflammation). 120 patients with amicrobic MAGI (mean age 27.0 ± 6.0 years) with mild-moderate ED (erectile dysfunction) according to IIEF-5 (International Index of Erectile Function 5 Items) scores underwent pharmacological treatment with Tadalafil 5 mg daily for six months. Before and after treatment these patients were evaluated through IIEF-5, semen analysis (according to WHO Criteria, 2010), SI-MAGI (Structured Interview about Male Accessory Gland Inflammation), and ultrasound evaluation...
2017: International Journal of Endocrinology
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