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Delayed ejaculation

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https://www.readbyqxmd.com/read/29453817/endocrine-and-psychological-aspects-of-sexual-dysfunction-in-klinefelter-patients
#1
A Ferlin, R Selice, S Angelini, M Di Grazia, N Caretta, F Cavalieri, A Di Mambro, C Foresta
Klinefelter syndrome is a frequent cause of hypogonadism, but despite hundreds of publications on different aspects of Klinefelter syndrome, only a few studies dealt with sexual dysfunction. In particular, testosterone is critical for various aspects of sexual response, but its role on sexuality in Klinefelter syndrome patients is debatable and no studies have evaluated the efficacy of testosterone treatment on sexual dysfunction in these subjects. Furthermore, the impact of psychological and relational aspects on sexual function of Klinefelter syndrome subjects is poorly defined...
February 17, 2018: Andrology
https://www.readbyqxmd.com/read/29441202/pulse-wave-doppler-ultrasound-of-testicular-arteries-and-their-relationship-with-semen-characteristics-in-healthy-bulls
#2
Alessia Gloria, Augusto Carluccio, Laura Wegher, Domenico Robbe, Claudio Valorz, Alberto Contri
Background: Semen evaluation is used to estimate the testicular function. In bulls, the spermatozoa present in the ejaculate are the result of a process that begun more than 2 mo earlier, bequeathing a delayed depiction of the actual function of the testis. Since testis vascularization might be critical for the gonad function, selected pulse wave Doppler ultrasound parameters were assessed in this study, for instance the peak systolic velocity, the end diastolic velocity and the resistive index of the testicular artery along the spermatic cord, the marginal portion of the testicular artery and the intratesticular branches of the testicular artery both in healthy adult and young bulls...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29432875/title-of-the-manuscript-new-tools-to-measure-ejaculatory-latency-arousal-to-ejaculation-time-interval-aeti-and-erection-to-ejaculation-time-interval-eeti-a-pilot-study
#3
Gajanan S Bhat, S Anuradha
OBJECTIVE: To evaluate the proposed novel tools, namely, Arousal to Ejaculation Time Interval (AETI) and Erection to Ejaculation Time Interval (EETI), to measure ejaculatory latency during different types of sexual encounters, in a pilot study. METHODS: The study period was from September 2016 to December 2016. After obtaining informed consent and institutional review board approval, the medical practitioners without any co-morbidity, who volunteered to participate, were asked to report the self assessed time taken to ejaculate following sexual arousal (AETI) and also following a sustained erection (EETI) during a sexual activity...
February 9, 2018: Urology
https://www.readbyqxmd.com/read/29299903/delayed-ejaculation-pathophysiology-diagnosis-and-treatment
#4
REVIEW
Ibrahim A Abdel-Hamid, Omar I Ali
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29284824/clozapine-induced-delayed-ejaculation
#5
Soumitra Das, Adesh Kumar Agrawal
No abstract text is available yet for this article.
November 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29031313/routes-to-diagnosis-for-men-with-prostate-cancer-men-s-cultural-beliefs-about-how-changes-to-their-bodies-and-symptoms-influence-help-seeking-actions-a-narrative-review-of-the-literature
#6
REVIEW
Michelle King-Okoye, Anne Arber, Sara Faithfull
PURPOSE: To examine the findings of existing studies in relation to men's cultural beliefs about changes to their bodies relevant to prostate cancer and how these affect interpretation of bodily changes and help-seeking actions. METHOD: We undertook a narrative review of studies conducted from 2004 to 2017 in 6 databases that highlighted men's beliefs and help-seeking actions for bodily changes suggestive of prostate cancer. RESULTS: Eighteen (18) studies reflecting men from various ethnicities and nationalities were included...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28904397/study-of-the-link-between-dopamine-transporter-gene-polymorphisms-and-response-to-paroxetin-and-escitalopram-in-patients-with-lifelong-premature-ejaculation
#7
T K Eltonsi, T M Tawfik, L A Rashed, S F GamalEl Din, M A Mahmoud
We evaluated the role of dopamine (DA) transporter gene polymorphism in lifelong premature ejaculation (LPE) and its role in determining the response to paroxetine and escitalopram. Eighty consecutive patients and controls were recruited. Sixty of them suffered from LPE. They were divided into two equal groups. One group received paroxetine 20 mg daily for 3 months and the other one received ecistalopram 20 mg daily for 3 months. Their wives were instructed to measure the intra-vaginal ejaculation latency time using stopwatch...
November 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28807505/delayed-ejaculation-and-associated-complaints-relationship-to-ejaculation-times-and-serum-testosterone-levels
#8
Abraham Morgentaler, Paula Polzer, Stanley Althof, Alexander Bolyakov, Craig Donatucci, Xiao Ni, Ankur B Patel, Shehzad Basaria
BACKGROUND: Although delayed ejaculation (DE) is typically characterized as a persistently longer than anticipated or desired time to ejaculation (or orgasm) during sexual activity, a timing-based definition of DE and its association with serum testosterone has not been established in a large cohort. AIM: To examine in an observational study estimated intravaginal ejaculatory latency time (IELT) and masturbatory ejaculation latency time (MELT) in men self-reporting DE, assess the association of IELT and MELT with serum testosterone levels, and determine whether correlation with demographic and sexual parameters exist...
September 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28679197/total-phallic-reconstruction-after-penile-amputation-for-donkey-bite-case-report-and-review-of-the-literature
#9
Francesco De Luca, Giulio Garaffa, Angela Maurizi, Emy Manzi, Carlo De Dominicis, David Ralph
There are very few reported cases of traumatic amputation of the male genitalia due to animal bite. The management involves thorough washout of the wounds, debridement, antibiotic prophylaxis, tetanus and rabies immunization followed by immediate reconstruction or primary wound closure with delayed reconstruction, when immediate reconstruction is not feasible. When immediate reconstruction is not feasible, long-term good functional and cosmetic results are still possible in the majority of cases by performing total phallic reconstruction...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28630352/structural-complexity-and-molecular-heterogeneity-of-a-butterfly-ejaculate-reflect-a-complex-history-of-selection
#10
Camille Meslin, Tamara S Cherwin, Melissa S Plakke, Brandon S Small, Breanna J Goetz, Nathan I Morehouse, Nathan L Clark
Male ejaculates are often structurally complex, and this complexity is likely to influence key reproductive interactions between males and females. However, despite its potential evolutionary significance, the molecular underpinnings of ejaculate structural complexity have received little empirical attention. To address this knowledge gap, we sought to understand the biochemical and functional properties of the structurally complex ejaculates of Pieris rapae butterflies. Males in this species produce large ejaculates called spermatophores composed of an outer envelope, an inner matrix, and a bolus of sperm...
July 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28540176/the-effect-of-8-oh-dpat-and-dapoxetine-on-gene-expression-in-the-brain-of-male-rats-during-ejaculation
#11
Xijun Qin, Xiaojun Ma, Dongping Tu, Zuliang Luo, Jie Huang, Changming Mo
The 5-HT1A receptor agonist 8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT) promotes ejaculation of male rats, whereas dapoxetine delays this process. However, the gene expression profile of the brain at ejaculation following administrationof these two compounds has not been fully elucidated. In the present study, a transcriptomic BodyMap was generated by conducting mRNA-Seq on brain samples of male Sprague-Dawley rats. The study included four groups: pre-copulatory control (CK) group, ejaculation (EJ) group, 0...
May 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28501545/betamethasone-causes-intergenerational-reproductive-impairment-in-male-rats
#12
Cibele Dos Santos Borges, Taina Louise Pacheco, Katiussia Pinho da Silva, Fábio Henrique Fernandes, Mary Gregory, André Sampaio Pupo, Daisy Maria F Salvadori, Daniel G Cyr, Wilma De G Kempinas
Prenatal betamethasone (BM) exposure in rats negatively impacts sperm quality and male fertility. Studies have shown that BM can cause multi-generational effects on the pituitary-adrenal-axis of rats. The objective of this study was to assess the reproductive development and fertility of male rats (F2) whose fathers (F1) were exposed to BM (0.1mg/kg) on gestational days 12, 13, 18 and 19. In F2 rats, there was a significant reduction in body weights of the BM-treated group at PND 1 as well as delayed onset of puberty, and decreases in FSH levels, Leydig cell volume, sperm number and motility, seminal vesicle contractility and ejaculated volume...
May 10, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28474611/patient-reported-ejaculatory-function-and-satisfaction-in-men-with-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#13
Min Chul Cho, Jung Kwon Kim, Sang Hoon Song, Sung Yong Cho, Sang Wook Lee, Soo Woong Kim, Jae-Seung Paick
This study aimed to investigate perceived ejaculatory function/satisfaction before treatment for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) and to identify associations between specific categories of ejaculatory dysfunctions (EjDs) and LUTS. A total of 1574 treatment-naïve men with LUTS/BPH were included in this study. All patients underwent routine evaluation for LUTS/BPH including the International Index of Erectile Function and a 5-item questionnaire developed to assess ejaculatory volume/force/pain/satisfaction/latency time...
May 2, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28465683/chronic-administration-of-tadalafil-improves-the-symptoms-of-patients-with-amicrobic-magi-an-open-study
#14
Sandro La Vignera, Rosita A Condorelli, Laura M Mongioi, Aldo E Calogero
Aim of this study was to evaluate the effects of pharmacological treatment with Tadalafil 5 mg daily on symptoms and quality of sperm parameters in selected patients with amicrobic MAGI (male accessory gland inflammation). 120 patients with amicrobic MAGI (mean age 27.0 ± 6.0 years) with mild-moderate ED (erectile dysfunction) according to IIEF-5 (International Index of Erectile Function 5 Items) scores underwent pharmacological treatment with Tadalafil 5 mg daily for six months. Before and after treatment these patients were evaluated through IIEF-5, semen analysis (according to WHO Criteria, 2010), SI-MAGI (Structured Interview about Male Accessory Gland Inflammation), and ultrasound evaluation...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28408390/lidocaine-prilocaine-spray-for-premature-ejaculation
#15
(no author information available yet)
Although premature ejaculation is the most common ejaculation problem, it is poorly understood and currently has no standard definition.(1) Typically, it involves reduced time to ejaculation, inability to control or delay ejaculation and associated distress.(1-5) Treatments that have been assessed include psychosexual counselling, antidepressants (e.g. selective serotonin reuptake inhibitors), phosphodiesterase type-5 inhibitors, tramadol and topical anaesthetic agents (e.g. lidocaine/prilocaine cream). A new formulation (cutaneous spray) of lidocaine/prilocaine (Fortacin-Plethora Solutions Ltd...
April 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28341756/distress-disease-desire-perspectives-on-the-medicalisation-of-premature-ejaculation
#16
Ylva Söderfeldt, Adam Droppe, Tim Ohnhäuser
The discovery that certain selective serotonin reuptake inhibitors delay ejaculation and the later development and approval of dapoxetine as an on-demand treatment option has led to a dramatic increase in medical interest in premature ejaculation. This paper analyses the diagnostic criteria and the discussion within the medical community about suitable treatments against the backdrop of theories of science, sex and gender. Our conclusion is that the diagnosis itself and the suggested treatments contribute to normative models of sexual conduct and therefore reinforce the norms that cause patients' distress over ejaculating 'too soon'...
March 23, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28261848/impact-of-physical-activity-on-patient-self-reported-outcomes-of-lifelong-premature-ejaculation-patients-results-of-a-prospective-randomised-sham-controlled-trial
#17
M F Kilinc, Y Aydogmus, Y Yildiz, O G Doluoglu
Previous studies have investigated whether physical activity increases serotonin hormone levels. Serotonin receptor dysfunction is one of the frequently accused factors of premature ejaculation (PE). Nevertheless, no studies up to date have demonstrated that the association between physical activity and premature ejaculation. We aimed to investigate the relationship between physical activity and PE and determine whether moderate physical activity might delay ejaculation time or be an alternative treatment for PE...
March 6, 2017: Andrologia
https://www.readbyqxmd.com/read/28159430/-jamaican-stone-a-potentially-lethal-remedy-for-delaying-ejaculation
#18
Belén Díaz-Antón, Guillermo Alonso-Deniz, Jose Luis Perez-Vela, Javier Molina-Martín de Nicolás, Belen Rubio-Alonso, Alfonso Jurado-Román, Ana Miguel-Gutierrez, Roberto Martin-Asenjo
Poisoning by ingestion of 'Jamaican Stone', a kind of cardioactive steroid, is extremely rare. However, mortality is very high. For this reason, when it occurs, an early and accurate diagnosis represents a critical challenge for clinicians. We present an unusual case of electrical storm caused by this substance.
February 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28124112/is-there-room-for-behavioral-and-modifiable-health-related-targets-in-the-lower-urinary-tract-symptoms-scenario
#19
Osamu Ikari, Brunno C F Sanches, João Carlos Cardoso Alonso, Fabiano A Simões, Ronald F Rejowski, Walker Wendel Laranja, Leonardo O Reis
PURPOSE: To better understand potential modifiable risk factors guiding preventive interventions against lower urinary tract symptoms (LUTS). METHODS: A prospective cross-sectional study, including healthy men aged 40-70 years under routine urological evaluation, measured the strength of association between the International Prostate Symptom Score (IPSS) and socio-demographic, lifestyle, and health-related factors using logistic and linear regression adjusted for confounding factors...
September 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28041925/complementary-and-alternative-medicine-for-management-of-premature-ejaculation-a-systematic-review
#20
REVIEW
Katy Cooper, Marrissa Martyn-St James, Eva Kaltenthaler, Kath Dickinson, Anna Cantrell, Shijie Ren, Kevan Wylie, Leila Frodsham, Catherine Hood
INTRODUCTION: Premature ejaculation (PE) is defined as ejaculation within 1 minute (lifelong PE) or 3 minutes (acquired PE), inability to delay ejaculation, and negative personal consequences. Management includes behavioral and pharmacologic approaches. AIM: To systematically review effectiveness, safety, and robustness of evidence for complementary and alternative medicine in managing PE. METHODS: Nine databases including Medline were searched through September 2015...
March 2017: Sexual Medicine
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