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acute otitis media

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https://www.readbyqxmd.com/read/28924860/facial-nerve-palsy-secondary-to-epstein-barr-virus-infection-of-the-middle-ear-in-pediatric-population-may-be-more-common-than-we-think
#1
Katarina Vogelnik, Aleš Matos
BACKGROUND: Facial nerve palsy is a rare complication of acute otitis media (AOM). The general understanding is that this complication has a bacterial cause although bacteria can be isolated from the middle ear only in approximately two-thirds of cases of AOM. Detection of viral agents from specimens obtained during myringotomy in patients with AOM suggests a possible role of viruses in the etiology of this disease. CASE PRESENTATIONS: We studied 5 otherwise healthy 17- to 27-month-old children who were referred to the Department of Otorhinolaryngology and Cervicofacial Surgery from December 2012 to January 2016 because of AOM and ipsilateral facial nerve palsy...
September 18, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28922054/economic-burden-of-pneumococcal-infections-in-children-under-5%C3%A2-years-of-age
#2
Mehmet Ceyhan, Yasemin Ozsurekci, Kubra Aykac, Basak Hacibedel, Egemen Ozbilgili
The present study aimed to determine the cost of childhood pneumococcal infections under 5 years of age and to provide further data for future health economy studies. Electronic medical records of children diagnosed with meningitis caused by S. pneumoniae and all-cause pneumonia, and acute otitis media (AOM) between January 2013-April 2014 were retrospectively evaluated. Direct costs for the treatments of hospitalized patients (pneumonia and pneumococcal meningitis) including costs of healthcare services consisted of costs of hospital bed, examination, laboratory analyses, scanning methods, consultation, vascular access procedures, and infusion and intravenous treatments...
September 18, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28918655/what-not-to-do-in-acute-otitis-media-the-top-five-recommendations-proposed-by-the-italian-society-of-preventive-and-social-pediatrics
#3
Elena Chiappini, Barbara Bortone, Mattia Doria, Massimo Landi, Giuseppe Di Mauro, Paola Marchisio
With the aim to reduce inappropriate procedures and antibiotic therapy in the management of acute otitis media (AOM) in children, the Italian Society of Preventive and Social Pediatrics (SIPPS) proposed a top five list of recommendations for clinical practice. Areas covered: AOM is one of the most frequent reasons for antibiotic prescription in pediatric age. The over-estimation of AOM is associated with inappropriate treatment, increased costs, adverse events and spread of antibiotic resistance. Thus, the most recent guidelines provided stringent diagnostic criteria and considered the 'watchful waiting' approach, limiting the immediate antibiotic therapy to a well-characterized subgroup of children...
September 19, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28914492/bacterial-etiology-of-recalcitrant-acute-otitis-media-in-sixty-two-children-high-risk-of-pathogen-colonization-after-treatment
#4
Izabela Korona-Glowniak, Elzbieta Mazur, Piotr Zychowski, Grazyna Niedzielska, Maria Koziol-Montewka, Anna Malm
Acute otitis media (AOM), common childhood infection that is one of leading cause of antibiotic prescriptions for children, is diagnosed at least once in approximately 80% of preschool children and 30-40% of them have recurrent episodes. Antibiotic treatment of AOM is usually empiric, without isolation of otopathogens from middle ear fluid and their antibiotic susceptibility testing. Due to the improper antibiotic use, the infection can persist in some cases, termed AOM treatment failure. This article is protected by copyright...
September 15, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28904032/antibiotic-therapy-for-children-with-acute-otitis-media
#5
Teeranai Sakulchit, Ran D Goldman
Question Acute otitis media is one of the most common infections in childhood. Routine prescription of antibiotics has led to adverse events and bacterial resistance to antibiotics. I have heard that "watchful waiting" is a good strategy to reduce this potential problem in children older than 6 months of age. Should I apply this strategy in my clinical practice? Answer Watchful waiting can be applied in selected children with nonsevere acute otitis media by withholding antibiotics and observing the child for clinical improvement...
September 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28894551/montelukast-versus-inhaled-mometasone-for-treatment-of-otitis-media-with-effusion-in-children-a-randomized-controlled-trial
#6
Mohammad Bagher Rahmati, Fatemeh Safdarian, Babak Shiroui, Shahram Zare, Naser Sadeghi
BACKGROUND: Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate in this issue. OBJECTIVE: To compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28893369/virulence-determinants-of-moraxella-catarrhalis-distribution-and-considerations-for-vaccine-development
#7
Luke V Blakeway, Aimee Tan, Ian R A Peak, Kate L Seib
Moraxella catarrhalis is a human-restricted opportunistic bacterial pathogen of the respiratory mucosa. It frequently colonizes the nasopharynx asymptomatically, but is also an important causative agent of otitis media (OM) in children, and plays a significant role in acute exacerbations of chronic obstructive pulmonary disease (COPD) in adults. As the current treatment options for M. catarrhalis infection in OM and exacerbations of COPD are often ineffective, the development of an efficacious vaccine is warranted...
September 12, 2017: Microbiology
https://www.readbyqxmd.com/read/28892455/modeling-specific-antibody-responses-to-natural-immunization-to-predict-a-correlate-of-protection-against-infection-before-commencing-a-clinical-vaccine-trial
#8
Anthony Almudevar, Michael E Pichichero
i) Background: Clinical trials of vaccines for children to prevent acute otitis media (AOM) infections caused by the bacteria Streptococcus pneumonia (Spn) are in Phase I. The objective of this study was to use serum antibody measurements to pneumococcal purified protein candidate antigens that occurred after natural "immunization" to predict a correlate of protection response needed following an injectable vaccine against AOM in children. METHODS: 590 nasal and serum samples were collected from 129 healthy children at 6, 9, 12, 15, 18, 24 and 30-36 months of age and when the child developed AOM...
September 11, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28881007/delayed-antibiotic-prescriptions-for-respiratory-infections
#9
REVIEW
Geoffrey Kp Spurling, Chris B Del Mar, Liz Dooley, Ruth Foxlee, Rebecca Farley
BACKGROUND: Concerns exist regarding antibiotic prescribing for respiratory tract infections (RTIs) owing to adverse reactions, cost, and antibacterial resistance. One proposed strategy to reduce antibiotic prescribing is to provide prescriptions, but to advise delay in antibiotic use with the expectation that symptoms will resolve first. This is an update of a Cochrane Review originally published in 2007, and updated in 2010 and 2013. OBJECTIVES: To evaluate the effects on clinical outcomes, antibiotic use, antibiotic resistance, and patient satisfaction of advising a delayed prescription of antibiotics in respiratory tract infections...
September 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28879826/management-of-paediatric-acute-mastoiditis-systematic-review
#10
R Loh, M Phua, C-K L Shaw
BACKGROUND: Acute mastoiditis remains the commonest intratemporal complication of otitis media in the paediatric population. There has been a lack of consensus regarding the diagnosis and management of acute mastoiditis, resulting in considerable disparity in conservative and surgical management. OBJECTIVES: To review the current literature, proposing recommendations for the management of paediatric acute mastoiditis and appraising the treatment outcomes. METHOD: A systematic review was conducted using PubMed, Web of Science and Cochrane Library databases...
September 7, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28865502/-validation-of-the-otitis-media-6-questionnaire-for-european-portuguese
#11
Ana Rita Lameiras, Deodato Silva, Assunção O'Neill, Pedro Escada
INTRODUCTION: Otitis media is one of the most prevalent childhood diseases. The impact of otitis media on quality of life of Portuguese children is unknown, because of the unavailability of a tool validated in European Portuguese to assess this consequence of otitis media. The Otitis Media-6 questionnaire (Otitis Media-6) is the most frequently used tool to assess health-related quality of life in children with otitis media. This study aims to create a version in the Portuguese language and culturally adapted to Portugal of the otitis media-6 questionnaire...
May 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28864559/cerebellar-abscesses-infective-endocarditis-and-bacteraemia-due-to-a-rare-pathogen-streptococcus-constellatus
#12
Rafael García Carretero
Intracranial infections may result from contiguity, such as mastoiditis or acute otitis media, or from haematogenous dissemination from an infectious source. Streptococcus constellatus, a coccus from the normal genital, oral and gastrointestinal flora, has a tendency to form abscesses, but not to cause infective endocarditis (IE). Also, S. constellatus is an extremely rare causative agent of brain abscess. We report the case of a woman with a colorectal tumour who presented with IE and cerebellar abscesses due to a S...
September 1, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28859019/age-specific-antibiotic-prescribing-and-adherence-to-guidelines-in-pediatric-patients-in-primary-care
#13
Verica Ivanovska, Karin Hek, Aukje K Mantel-Teeuwisse, Hubert G M Leufkens, Liset van Dijk
BACKGROUND: Most antibiotics in children are used to treat viral and self-limiting conditions. This study aims to compare physicians' adherence to guidelines on antibiotic prescribing in fever and in ear and respiratory infections to children in different age groups in the Netherlands. METHODS: Data were used from the NIVEL Primary Care Database. For all pediatric episodes of fever, acute otitis media (AOM), streptococcal pharyngitis (strep throat), sinusitis, acute tonsillitis, acute bronchitis/bronchiolitis and pneumonia in 2012, we determined whether national guidelines were followed in regard to whether an antibiotic was prescribed, and the type of antibiotic...
August 28, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28852326/cost-effectiveness-analysis-of-a-universal-mass-vaccination-program-with-a-phid-cv-2-1-schedule-in-malaysia
#14
Xiao Jun Wang, Ashwini Saha, Xu-Hao Zhang
BACKGROUND: Currently, two pediatric pneumococcal conjugate vaccines are available in the private market of Malaysia-13-valent pneumococcal conjugate vaccine (PCV13) and pneumococcal polysaccharide and non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV). This study aimed to evaluate the cost-effectiveness of a universal mass vaccination program with a PHiD-CV 2+1 schedule versus no vaccination or with a PCV13 2+1 schedule in Malaysia. METHODS: A published Markov cohort model was adapted to evaluate the epidemiological and economic consequences of programs with no vaccination, a PHiD-CV 2+1 schedule or a PCV13 2+1 schedule over a 10-year time horizon...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28851343/teaching-the-pediatric-ear-exam-and-diagnosis-of-acute-otitis-media-a-teaching-and-assessment-model-in-three-groups
#15
Caroline R Paul, Craig L Gjerde, Gwen McIntosh, Lori S Weber
BACKGROUND: The serious consequences of inaccurate diagnosis of acute otitis media have led to a call for greater education to develop proficient pediatric otoscopy skills. Despite the clinical and educational needs, peer-reviewed standardized curricula with validated assessment instruments remain limited. This study evaluated a pediatric otoscopy curriculum incorporated into the Pediatric medical student clerkship with use of outcome measures that included assessment of skills with real patients...
August 29, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28802367/impact-of-pneumococcal-conjugate-vaccines-on-otitis-media-a-review-of-measurement-and-interpretation-challenges
#16
REVIEW
Ivo Vojtek, Marcus Nordgren, Bernard Hoet
Acute otitis media (AOM) is among the most frequent childhood diseases and is caused by various bacterial and viral etiological agents. In this article, we provide an overview of published studies assessing the impact of higher-valent pneumococcal conjugate vaccines (PCVs) on AOM. In some instances, reports of PCV impact on complications of AOM have been included. While randomized controlled trials (RCTs) allow for the most precise assessment of vaccine efficacy against AOM, observational studies provide answers to questions regarding the public health value of these vaccines in real-life settings...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28796849/neutrophil-extracellular-traps-and-fibrin-in-otitis-media-analysis-of-human-and-chinchilla-temporal-bones
#17
Patricia A Schachern, Geeyoun Kwon, David E Briles, Patricia Ferrieri, Steven Juhn, Sebahattin Cureoglu, Michael M Paparella, Vladimir Tsuprun
Background: Bacterial resistance in acute otitis can result in bacterial persistence and biofilm formation, triggering chronic and recurrent infections. Objective: To investigate the middle ear inflammatory response to bacterial infection in human and chinchilla temporal bones. Design, Setting, and Participants: Six chinchillas underwent intrabullar inoculations with 0.5 mL of 106 colony-forming units (CFUs) of Streptococcus pneumoniae, serotype 2...
August 10, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28790141/prognostic-factors-for-treatment-failure-in-acute-otitis-media
#18
RANDOMIZED CONTROLLED TRIAL
Paula A Tähtinen, Miia K Laine, Aino Ruohola
BACKGROUND AND OBJECTIVES: Antimicrobial treatment is effective in the management of acute otitis media (AOM), but approximately half of the children may recover without antimicrobial agents. By identifying patients who may not require antimicrobial treatment for the management of AOM, the use of antimicrobial agents could be substantially reduced. Our aim was to identify subgroups of children with AOM who would benefit most from antimicrobial treatment and children who could be suitable for initial observation...
September 2017: Pediatrics
https://www.readbyqxmd.com/read/28764189/comparison-of-efficacy-and-safety-of-cefpodoxime-and-amoxicillin-clavulanate-potassium-in-paediatric-acute-otitis-media-in-children-below-two-years-a-prospective-longitudinal-study
#19
Arijit Ghosh, Sayan Chatterjee
INTRODUCTION: Acute Otitis Media (AOM) is one of the frequently diagnosed diseases in children below two years. Amoxicillin-clavulanate potassium is the first line drug in treatment of Paediatric AOM (PAOM). Cefpodoxime has good antimicrobial activity against various types of microorganisms that include causative microorganisms of PAOM. AIM: To compare the efficacy and safety of cefpodoxime and amoxicillin-clavulanate potassium for the treatment of PAOM in children below two years...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763425/frequency-of-acute-otitis-media-in-children-under-24-months-of-age-before-and-after-the-introduction-of-the-10-valent-pneumococcal-conjugate-vaccine-into-the-national-immunization-program-in-chile
#20
Andrés Rosenblut, Macarena Rosenblut, Karen García, Ximena Maul
BACKGROUND: Streptococcus pneumoniae is the leading cause of acute otitis media (AOM). Pneumococcal non-typable Haemophilus influenzae Protein D Conjugate Vaccine (PCV-10) was introduced to the Chilean national immunization program (NIP) in 2011. The aim of this study was to estimate the frequency of AOM in children < 24 months of age attending the Emergency Department (ED) of Hospital Sótero del Río (HSR) 4 years before and 4 years after the introduction of PCV-10 in the Chilean NIP...
July 31, 2017: Pediatric Infectious Disease Journal
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