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https://www.readbyqxmd.com/read/29245182/an-efficient-parallel-simulation-of-unsteady-blood-flows-in-patient-specific-pulmonary-artery
#1
Fande Kong, Vitaly Kheyfets, Ender Finol, Xiao-Chuan Cai
Simulation of blood flows in the pulmonary artery provides some insight into certain diseases by examining the relationship between some continuum metrics, e.g. the wall shear stress acting on the vascular endothelium, which responds to flow-induced mechanical forces by releasing vasodilators/constrictors. In [?kheyfets2015patient], V. Kheyfets studies numerically a patient-specific pulmonary circulation to show that decreasing wall shear stress is correlated with increasing pulmonary vascular impedance. In this paper, we develop a scalable parallel algorithm based on domain decomposition methods to investigate an unsteady model with patient specific pulsatile waveforms as the inlet boundary condition...
December 15, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29235420/a-self-care-problem-solving-and-mindfulness-intervention-for-informal-caregivers-of-people-with-motor-neurone-disease-a-pilot-study
#2
Anna Ugalde, Susan Mathers, Nicole Hennessy Anderson, Peter Hudson, Liliana Orellana, Cathy Gluyas
BACKGROUND: Informal caregivers of people with motor neurone disease (MND) take on an extensive role. Caregivers are at increased risk of experiencing psychological distress and burden, yet, there is a lack of intervention programmes to support them. AIM: The aim of this study was to investigate the feasibility and acceptability of a therapeutic group intervention promoting self-care, problem-solving and mindfulness to informal caregivers of people with MND. DESIGN: Pilot study that utilised a one-arm pre- and post-design...
November 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29229436/a-longitudinal-analysis-of-allostatic-load-among-a-multi-ethnic-sample-of-midlife-women-findings-from-the-study-of-women-s-health-across-the-nation
#3
Laura Chyu, Dawn M Upchurch
OBJECTIVES: We examined longitudinal patterns and sociodemographic correlates of allostatic load (AL), a measure of cumulative biological risk and aging, in a sample of midlife women consisting of non-Hispanic White, African American, Chinese, and Japanese women. METHODS: Longitudinal cohort data from the Study of Women's Health Across the Nation were used to examine AL patterns in midlife women ages 42-53 (n = 1,932). AL measures were created using 10 biomarkers representing cardiovascular, inflammatory, neuroendocrine, and metabolic system functioning...
December 8, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29226634/post-intervention-sustainability-of-a-brief-psycho-educational-support-group-intervention-for-family-caregivers-of-cancer-patients
#4
Joyce Y S Tan, Kevin F Y Lam, Haikel A Lim, Shi Min Chua, Ee Heok Kua, Konstadina Griva, Rathi Mahendran
INTRODUCTION: Family caregivers of cancer patients experience many negative effects due to the heavy responsibility involved. Although various psychosocial interventions have been found to improve caregivers' quality of life (QOL), the sustainability of the benefits of these interventions over time has been less consistently investigated and hence less clearly established. Extending previous research on the immediate post-intervention effects, this study aims to examine the trajectories of change in caregivers QOL over an 8-week follow-up period...
December 11, 2017: Asia-Pacific Psychiatry: Official Journal of the Pacific Rim College of Psychiatrists
https://www.readbyqxmd.com/read/29225908/an-unusual-presentation-of-tyrosine-hydroxylase-deficiency
#5
Linn E Katus, Steven J Frucht
Background: Dopa-responsive dystonia (DRD) has largely been associated with autosomal dominant mutations in the GCH1 gene leading to GTP cyclohydrolase 1 deficiency. More recently, a deficiency in tyrosine hydroxylase (TH) has been recognized to cause DRD. This is a rare disorder resulting from genetic mutations in the TH gene on chromosome 11. The phenotype ranges from DRD with complete resolution on levodopa to infantile parkinsonism and encephalopathy only partially responsive to levodopa...
2017: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/29218965/moral-courage-in-undergraduate-nursing-students-a-literature-review
#6
Laurie Bickhoff, Peter M Sinclair, Tracy Levett-Jones
Aim: The aim of this review was to explore factors which facilitate or inhibit undergraduate nursing students’ willingness to demonstrate moral courage when confronted by poor patient care. Methods: Included papers were those that met the criteria of being qualitative research that explored undergraduate nursing students’ depictions of situations where moral courage was or was not demonstrated during clinical placements, with a particular focus on situations that impacted or had the potential to impact the quality of patient care...
2017: Collegian: Journal of the Royal College of Nursing, Australia
https://www.readbyqxmd.com/read/29214946/psychosomatic-and-psychosocial-questions-regarding-bariatric-surgery-what-do-we-know-or-what-do-we-think-we-know
#7
Stephan Herpertz, Henrik Kessler, Sebastian Jongen
SUBJECT: In view of the epidemic increase in severe obesity and the ineffectiveness of conservative weight-loss interventions, bariatric surgery delivers compelling results for patients with class II (BMI ≥ 35 kg/m²) and class III obesity (BMI ≥ 40 kg/m²), not only in reducing weight over the long term, but also in reducing obesity-related somatic comorbidity and improving psychosocial functioning and quality of life. Investigations into the psychosocial aspects of obesity surgery have proliferated over the last 15 years, providing a huge amount of essential research data...
December 2017: Zeitschrift Für Psychosomatische Medizin und Psychotherapie
https://www.readbyqxmd.com/read/29214137/speak-up-increasing-conversational-volume-in-a-child-with-autism-spectrum-disorder
#8
Leigh Edgerton, Byron Wine
Deficits in social interactions are a hallmark of autism spectrum disorder. This study examined one relatively uncommon aspect of social interactions that has not received much attention from the literature: appropriate conversational volume. Conversational speech volume was measured using a commercially available application, and a package intervention was developed that consisted of feedback from the voice measuring application, signaling from a wrist bracelet, and differential reinforcement. The intervention was evaluated in an ABAB design and speaking at conversational volume was significantly increased when the intervention was in place and in probe conditions...
December 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/29212511/comparing-the-chinese-versions-of-two-knee-specific-questionnaires-ikdc-and-koos-reliability-validity-and-responsiveness
#9
Chien-Chih Huang, Wen-Shiang Chen, Mei-Wun Tsai, Wendy Tzyy-Jiuan Wang
BACKGROUND: The International Knee Documentation Committee Subjective Knee Form (IKDC) and the Knee Injury and Osteoarthritis Outcome Score (KOOS) are knee-specific questionnaires that have been widely used and translated into numerous languages. However, the differences in the psychometric properties between the Chinese IKDC and KOOS remain unclear. The purpose of this study was to conduct a cross-cultural adaptation of the Chinese IKDC and Chinese KOOS and to compare the psychometric properties of these two measures in patients with various knee injuries from the acute stage up to 12 weeks after receiving treatment...
December 6, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29197905/physician-advocacy-in-western-medicine-a-21st-century-challenge
#10
Philip Bagshaw, Pauline Barnett
Physician advocacy occurs when doctors speak up for the health and healthcare of patients and communities. Historically, this was strong in some Western countries with doctors finding that it enhanced their authority, prestige and power. But it weakened in the 20th century when the biomedical model of heath triumphed and medicine became a dominant profession. In the second part of the 20th century, this dominance was threatened by political, technological and socioeconomic forces. These weakened medicine's state support, brought it under managerial control and undermined the social contract on which trust between doctors and the community was based...
December 1, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29196587/perceptions-of-family-members-nurses-and-physicians-on-involving-patients-families-in-delirium-prevention
#11
Pamela L Smithburger, Amanda S Korenoski, Sandra L Kane-Gill, Sheila A Alexander
BACKGROUND: Delirium occurs in up to 80% of patients admitted to an intensive care unit. Nonpharmacologic delirium-prevention strategies, which are commonly used by the bedside nurse, have reduced the incidence and duration of delirium in patients in the intensive care unit. With increasing demands on the nurse, strategies such as including the patient's family in delirium prevention activities should be investigated. OBJECTIVE To determine opinions and willingness of health care providers to involve patients' families in nonpharmacologic delirium-prevention activities in the intensive care unit, and of patients' families to be involved...
December 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/29190103/tunneling-reaction-kinetics-for-the-hydrogen-abstraction-reaction-h-h2s-%C3%A2-h2-hs-in-the-interstellar-medium
#12
Thanja Lamberts, Johannes Kästner
The hydrogen abstraction reaction between H and H2S, yielding HS and H2 as products, has been studied within the framework of interstellar surface chemistry. High-temperature rate constants up to 2000 K are calculated in the gas phase and are in agreement with previously reported values. Subsequently low-temperature rate constants down to 55 K are presented for the first time that are of interest to astrochemistry, i.e., covering both bimolecular and unimolecular reaction mechanisms. For this, a so-called implicit surface model is used...
November 30, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29189435/investigating-physicians-views-on-soft-signals-in-the-context-of-their-peers-performance
#13
Myra van den Goor, Milou Silkens, Maas Jan Heineman, Kiki Lombarts
BACKGROUND: Physicians are responsible for delivering high quality of care. In cases of underperformance, hindsight knowledge indicates forewarning being potentially available in terms of concerns, signs, or signals. It is not known how the physicians involved perceive such signals. PURPOSE: To openly explore how physicians perceive soft signals and react on them. METHODS: In-depth interviews with 12 hospital-based physicians from various specialties and institutions following the interpretative phenomenological analysis approach...
November 14, 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/29189255/shut-up-and-let-the-women-speak
#14
Mark Darby
An NP remembers sage advice from a Dominican priest.
December 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/29188346/-diagnosis-treatment-and-follow-up-of-testicular-cancer
#15
Susanne Krege
BACKGROUND: Testicular cancer is a disease of young adult men, and it is curable in most cases. Even in advanced disease, cure rates reach 80 % nowadays. This was achieved by consistently performing studies concerning the different stages of disease. TREATMENT AND FOLLOW-UP CARE: The concept of treatment is interdisciplinary. After removal of the affected testis, histology and stage determine further therapy, which can be active surveillance, polychemotherapy, radiotherapy, surgery, or a combination of these...
November 29, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29186417/examining-influences-on-speaking-up-among-critical-care-healthcare-providers-in-the-united-arab-emirates
#16
Hanan H Edrees, Mohd Nasir Mohd Ismail, Bernadette Kelly, Christine A Goeschel, Sean M Berenholtz, Peter J Pronovost, Ali Abdul Kareem Al Obaidli, Sallie J Weaver
Objective: Assess perceived barriers to speaking up and to provide recommendations for reducing barriers to reporting adverse events and near misses. Design, setting, participants, intervention: A six-item survey was administered to critical care providers in 19 Intensive Care Units in Abu Dhabi as part of an organizational safety and quality improvement effort. Main outcome measures: Questions elicited perspectives about influences on reporting, perceived barriers and recommendations for conveying patient safety as an organizational priority...
November 23, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29176419/the-role-of-checklists-and-human-factors-for-improved-patient-safety-in-plastic-surgery
#17
Claude Oppikofer, David Schwappach
LEARNING OBJECTIVES: After studying the article, participants should be able to: 1. Describe the role of human factors and nontechnical skills for patient safety and recognize the need for customization of surgical checklists. 2. Apply encouragement to speaking up and understand the importance of patient involvement for patient safety. 3. Recognize the potential for improvement regarding patient safety in their own environment and take a leading role in the patient safety process. 4. Assess their own safety status and develop measures to avoid unnecessary distraction in the operating room...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29176109/routine-screening-for-pregnancy-intention-to-address-unmet-reproductive-health-needs-in-two-urban-federally-qualified-health-centers
#18
Elizabeth Kvach, Jane Lose, Hayley Marcus, Lucy Loomis
OBJECTIVE: The goal of this project was to increase rates of screening for pregnancy intention in primary care. METHODS: Two urban federally qualified health centers with diverse patient populations undertook a quality improvement project to increase rates of routine screening for pregnancy intention among pre-menopausal non-pregnant women ages 12-45 without history of sterilization. Responses were recorded in the electronic medical record (EMR). RESULTS: Screening rates of eligible women increased from 0% to 68...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/29174320/-prerequisite-for-hematopoietic-cellular-therapy-programs-to-set-up-chimeric-antigen-receptor-t-cell-therapy-car-t-cells-guidelines-from-the-french-speaking-society-of-bone-marrow-transplantation-and-cellular-therapy-sfgm-tc
#19
Ibrahim Yakoub-Agha, Christophe Ferrand, Yves Chalandon, Caroline Ballot, Cristina Castilla Llorente, Marina Deschamps, Jordan Gauthier, Myriam Labalette, Jérôme Larghero, Camille Maheux, Anne-Sophie Moreau, Pauline Varlet, Marie-Odile Pétillon, Marine Pinturaud, Marie Thérèse Rubio, Christian Chabannon
CAR T-cells are autologous or allogeneic human lymphocytes that are genetically engineered to express a chimeric antigen receptor targeting an antigen expressed on tumor cells such as CD19. CAR T-cells represent a new class of medicinal products, and belong to the broad category of Advanced Therapy Medicinal Products (ATMPs), as defined by EC Regulation 2007-1394. Specifically, they are categorized as gene therapy medicinal products. Although CAR T-cells are cellular therapies, the organization for manufacturing and delivery is far different from the one used to deliver hematopoietic cell grafts, for different reasons including their classification as medicinal products...
November 23, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/29171285/a-human-right-to-literacy-education-implications-for-serving-syrian-refugee-children
#20
Mary Claire Wofford, Sana Tibi
Forty percent of Syrian refugees are younger than 12, and many have not attended school for up to five years, disadvantaging them academically, emotionally, and psychosocially. Article 19 of the Universal Declaration of Human Rights dictates "the right to freedom of opinion and expression…and to seek, receive and impart information and ideas…)". Resettled refugee children face the challenge of integration into majority-English school systems with limited ability to express themselves or linguistic means to access education...
November 24, 2017: International Journal of Speech-language Pathology
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