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Schizophrenia games

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https://www.readbyqxmd.com/read/28924869/the-educational-potential-of-youtube
#1
Haley T Godwin, Murtaza Khan, Peter Yellowlees
OBJECTIVE: The objective of this paper was to examine the educational potential and effectiveness of a 3 min video clip of a simulation of schizophrenia published online at YouTube. METHOD: Researchers examined the 267 public comments published on the video-sharing website YouTube over 8 years by viewers of a schizophrenia simulation video titled "virtual hallucinations" made in the Second Life game platform. Comments were independently categorized into six groupings, then cooperatively finalized, and qualitatively analyzed...
September 18, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28895568/response-to-targeted-cognitive-training-correlates-with-change-in-thalamic-volume-in-a-randomized-trial-for-early-schizophrenia
#2
Ian S Ramsay, Susanna Fryer, Alison Boos, Brian J Roach, Melissa Fisher, Rachel Loewy, Sophia Vinogradov, Daniel H Mathalon
Reduced thalamic volume is consistently observed in schizophrenia, and correlates with cognitive impairment. Targeted cognitive training (TCT) of auditory processing in schizophrenia drives improvements in cognition that are believed to result from functional neuroplasticity in prefrontal and auditory cortices. In this study, we sought to determine whether response to TCT is also associated with structural neuroplastic changes in thalamic volume in patients with early schizophrenia (ESZ). Additionally, we examined baseline clinical, cognitive, and neural characteristics predictive of a positive response to TCT...
September 12, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28878702/stigma-stop-a-serious-game-against-the-stigma-toward-mental-health-in-educational-settings
#3
Adolfo J Cangas, Noelia Navarro, José M A Parra, Juan J Ojeda, Diego Cangas, Jose A Piedra, Jose Gallego
This paper presents the results from the application of a serious game called Stigma-Stop among a group of high school students with the aim of reducing the stigma toward mental illnesses. The video game features characters with various mental disorders (schizophrenia, depression, bipolar disorder, and panic disorder with agoraphobia) and provides information about these problems. Additionally, the game asks players about whether they have ever felt the same as the characters, if they believe the characters are psychologically well, and if they think they could help these individuals...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28845238/trait-aspects-of-auditory-mismatch-negativity-predict-response-to-auditory-training-in-individuals-with-early-illness-schizophrenia
#4
Bruno Biagianti, Brian J Roach, Melissa Fisher, Rachel Loewy, Judith M Ford, Sophia Vinogradov, Daniel H Mathalon
BACKGROUND: Individuals with schizophrenia have heterogeneous impairments of the auditory processing system that likely mediate differences in the cognitive gains induced by auditory training (AT). Mismatch negativity (MMN) is an event-related potential component reflecting auditory echoic memory, and its amplitude reduction in schizophrenia has been linked to cognitive deficits. Therefore, MMN may predict response to AT and identify individuals with schizophrenia who have the most to gain from AT...
2017: Neuropsychiatric Electrophysiology
https://www.readbyqxmd.com/read/28696479/a-web-based-game-for-teaching-facial-expressions-to-schizophrenic-patients
#5
Kemal Hakan Gülkesen, Filiz Isleyen, Buket Cinemre, Mehmet Kemal Samur, Semiha Sen Kaya, Nese Zayim
BACKGROUND: Recognizing facial expressions is an important social skill. In some psychological disorders such as schizophrenia, loss of this skill may complicate the patient's daily life. Prior research has shown that information technology may help to develop facial expression recognition skills through educational software and games. OBJECTIVES: To examine if a computer game designed for teaching facial expressions would improve facial expression recognition skills of patients with schizophrenia...
July 12, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28662466/informationally-administered-reward-enhances-intrinsic-motivation-in-schizophrenia
#6
Hyeon-Seung Lee, Seon-Kyeong Jang, Ga-Young Lee, Seon-Cheol Park, Alice Medalia, Kee-Hong Choi
Even when individuals with schizophrenia have an intact ability to enjoy rewarding moments, the means to assist them to translate rewarding experiences into goal-directed behaviors is unclear. The present study sought to determine whether informationally administered rewards enhance intrinsic motivation to foster goal-directed behaviors in individuals with schizophrenia (SZ) and healthy controls (HCs). Eighty-four participants (SZ=43, HCs=41) were randomly assigned to conditions involving either a performance-contingent reward with an informationally administered reward or a task-contingent reward with no feedback...
June 17, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28581530/mental-and-behavioural-disorders-in-the-icd-11-concepts-methodologies-and-current-status
#7
REVIEW
Wolfgang Gaebel, Jürgen Zielasek, Geoffrey M Reed
This review provides an overview of the concepts, methods and current status of the development of the Eleventh Revision of the Mental and Behavioural Disorders chapter of the International Classification of Diseases and Related Health Problems (ICD-11) by the World Health Organization (WHO). Given the global use of the current version (ICD-10) for a wide range of applications in clinical practice and health statistics, a major aim of the development process for ICD-11 has been to increase the utility of the classification system...
April 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28578921/impaired-social-cognition-in-schizophrenia-during-the-ultimatum-game-an-eeg-study
#8
Sibylle K Horat, Grégoire Favre, Anne Prévot, Joseph Ventura, François R Herrmann, Isabelle Gothuey, Marco C G Merlo, Pascal Missonnier
BACKGROUND: Schizophrenia has a core feature of cognitive dysfunctions. Since these deficits are predictive for patients' functional outcome, understanding their origin is of great importance to improve their daily lives. A specific component of the deficit involves social decision-making, which can be studied using the Ultimatum Game (UG). In this task, a "proposer" proposes a share of money to a "responder", who can either accept or reject this offer. If the responder accepts the proposal, both win money...
June 1, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28560254/unravelling-socio-motor-biomarkers-in-schizophrenia
#9
Piotr Słowiński, Francesco Alderisio, Chao Zhai, Yuan Shen, Peter Tino, Catherine Bortolon, Delphine Capdevielle, Laura Cohen, Mahdi Khoramshahi, Aude Billard, Robin Salesse, Mathieu Gueugnon, Ludovic Marin, Benoit G Bardy, Mario di Bernardo, Stephane Raffard, Krasimira Tsaneva-Atanasova
We present novel, low-cost and non-invasive potential diagnostic biomarkers of schizophrenia. They are based on the 'mirror-game', a coordination task in which two partners are asked to mimic each other's hand movements. In particular, we use the patient's solo movement, recorded in the absence of a partner, and motion recorded during interaction with an artificial agent, a computer avatar or a humanoid robot. In order to discriminate between the patients and controls, we employ statistical learning techniques, which we apply to nonverbal synchrony and neuromotor features derived from the participants' movement data...
2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/28476141/theory-of-mind-deficits-partly-mediate-impaired-social-decision-making-in-schizophrenia
#10
Liuqing Yang, Peifu Li, Haiying Mao, Huiling Wang, Chang Shu, Vibeke Bliksted, Yuan Zhou
BACKGROUND: Using paradigms from game theory, researchers have reported abnormal decision-making in social context in patients with schizophrenia. However, less is known about the underpinnings of the impairment. This study aimed to test whether theory of mind (ToM) deficits and/or neurocognitive dysfunctions mediate impaired social decision-making in patients with schizophrenia. METHODS: We compared thirty-five patients with schizophrenia to thirty-eight matched healthy controls with regard to social decision-making using the mini Ultimatum Game (mini UG), a paradigm from game theory...
May 5, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28036406/winner-s-curse-correction-and-variable-thresholding-improve-performance-of-polygenic-risk-modeling-based-on-genome-wide-association-study-summary-level-data
#11
Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja T Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra Silverman, Montserrat Garcia-Closas, Chao Agnes Hsiung, Jonine D Figueroa, Victoria K Cortessis, Núria Malats, Margaret R Karagas, Paolo Vineis, I-Shou Chang, Dongxin Lin, Baosen Zhou, Adeline Seow, Keitaro Matsuo, Yun-Chul Hong, Neil E Caporaso, Brian Wolpin, Eric Jacobs, Gloria M Petersen, Alison P Klein, Donghui Li, Harvey Risch, Alan R Sanders, Li Hsu, Robert E Schoen, Hermann Brenner, Rachael Stolzenberg-Solomon, Pablo Gejman, Qing Lan, Nathaniel Rothman, Laufey T Amundadottir, Maria Teresa Landi, Douglas F Levinson, Stephen J Chanock, Nilanjan Chatterjee
Recent heritability analyses have indicated that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex diseases based on polygenic risk score (PRS), a simple modelling technique that can be implemented using summary-level data from the discovery samples. We herein propose modifications to improve the performance of PRS. We introduce threshold-dependent winner's-curse adjustments for marginal association coefficients that are used to weight the single-nucleotide polymorphisms (SNPs) in PRS...
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27837574/there-is-no-safe-threshold-for-lead-exposure-%C3%AE-literature-review
#12
REVIEW
Th Vorvolakos, S Arseniou, M Samakouri
Lead was one of the most dangerous environmental toxic substances for a long time in western countries, and this is still the case for many places on earth today. Its neurotoxic potential is highly significant but its secure blood level concentration remains unknown. The aim of this study was to approach the above issue from the perspective of social psychiatry. A systematic search was made of Dialog and Datastar interfaces for data regarding the neuropsychiatric complications of direct or chronic exposure to lead, and a review of the relevant literature was conducted using the databases Medline, Embase, CAB Global Health and Cochrane...
July 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/27568887/risky-decision-making-under-risk-in-schizophrenia-a-deliberate-choice
#13
Anya Pedersen, Robert Göder, Samuel Tomczyk, Patricia Ohrmann
BACKGROUND AND OBJECTIVES: Patients with schizophrenia reveal impaired decision-making strategies causing social, financial and health care problems. The extent to which deficits in decision-making reflect intentional risky choices in schizophrenia is still under debate. Based on previous studies we expected patients with schizophrenia to reveal a riskier performance on the GDT and to make more disadvantageous decisions on the IGT. METHODS: In the present study, we investigated 38 patients with schizophrenia and 38 matched healthy control subjects with two competing paradigms regarding feedback: (1) The Game of Dice Task (GDT), in which the probabilities of winning or losing are stable and explicitly disclosed to the subject, to assess decision-making under risk and (2) the Iowa Gambling Task (IGT), which requires subjects to infer the probabilities of winning or losing from feedback, to investigate decision-making under ambiguity...
August 7, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27445739/does-a-combination-of-virtual-reality-neuromodulation-and-neuroimaging-provide-a-comprehensive-platform-for-neurorehabilitation-a-narrative-review-of-the-literature
#14
REVIEW
Wei-Peng Teo, Makii Muthalib, Sami Yamin, Ashlee M Hendy, Kelly Bramstedt, Eleftheria Kotsopoulos, Stephane Perrey, Hasan Ayaz
In the last decade, virtual reality (VR) training has been used extensively in video games and military training to provide a sense of realism and environmental interaction to its users. More recently, VR training has been explored as a possible adjunct therapy for people with motor and mental health dysfunctions. The concept underlying VR therapy as a treatment for motor and cognitive dysfunction is to improve neuroplasticity of the brain by engaging users in multisensory training. In this review, we discuss the theoretical framework underlying the use of VR as a therapeutic intervention for neurorehabilitation and provide evidence for its use in treating motor and mental disorders such as cerebral palsy, Parkinson's disease, stroke, schizophrenia, anxiety disorders, and other related clinical areas...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27262087/patients-with-schizophrenia-are-less-prone-to-interpret-virtual-others-empathetic-questioning-as-helpful
#15
Zina Berrada-Baby, Ali Oker, Matthieu Courgeon, Mathieu Urbach, Nadine Bazin, Michel-Ange Amorim, Jean-Claude Martin, Christine Passerieux, Paul Roux, Eric Brunet-Gouet
Individuals with schizophrenia are impaired in their neurocognition and present cognitive biases. These impairments may lead to a deficit in recognizing helping intentions of others. To investigate recognition of help, we designed a card-guessing game (Virtual Help Recognition Paradigm) involving two successive virtual agents asking questions to the participant at different moments of the game. These questions were either empathetic (i.e. on the subject's feelings) or non-empathetic (i.e. on technical aspects of the game)...
August 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27187170/autism-and-psychosis-expressions-diametrically-modulate-the-right-temporoparietal-junction
#16
Ahmad M Abu-Akel, Ian A Apperly, Stephen J Wood, Peter C Hansen
The mentalizing network is atypically activated in autism and schizophrenia spectrum disorders. While these disorders are considered diagnostically independent, expressions of both can co-occur in the same individual. We examined the concurrent effect of autism traits and psychosis proneness on the activity of the mentalizing network in 24 neurotypical adults while performing a social competitive game. Activations were observed in the paracingulate cortex and the right temporoparietal junction (rTPJ). Autism traits and psychosis proneness did not modulate activity within the paracingulate or the dorsal component of the rTPJ...
October 2017: Social Neuroscience
https://www.readbyqxmd.com/read/27148093/a-serious-game-to-improve-cognitive-functions-in-schizophrenia-a-pilot-study
#17
Isabelle Amado, Lindsay Brénugat-Herné, Eric Orriols, Colombe Desombre, Maxine Dos Santos, Zelda Prost, Marie-Odile Krebs, Pascale Piolino
Cognitive deficits in schizophrenia impair everyday functioning and instrumental daily living activities. These disabilities can be partly responsible for chronicity and institutionalization. We present here a virtual reality (VR) tool in which patients with schizophrenia performed a virtual game in an imaginary town during a 3-month program. In a pilot study, seven patients with schizophrenia (DSM-5), institutionalized for many years, attended weekly 1-h-and-a-half sessions organized by two clinicians. During the first sessions, they listed together the difficulties they experienced in everyday organization and planning...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27105939/effectiveness-of-social-media-interventions-for-people-with-schizophrenia-a-systematic-review-and-meta-analysis
#18
REVIEW
Maritta Välimäki, Christina Athanasopoulou, Mari Lahti, Clive E Adams
BACKGROUND: Recent studies have shown that people with serious mental disorders spend time online for the purposes of disclosure, information gathering, or gaming. However, coherent information on the effects of social media on treatment for people with schizophrenia is still lacking. OBJECTIVE: Our aim was to determine the effects of social media interventions for supporting mental health and well-being among people with schizophrenia. METHODS: A systematic review and meta-analysis were undertaken to determine the effects of social media interventions for supporting mental health and well-being among people with schizophrenia...
April 22, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27105181/the-groundskeeper-gaming-platform-as-a-diagnostic-tool-for-attention-deficit-hyperactivity-disorder-sensitivity-specificity-and-relation-to-other-measures
#19
Stephen V Faraone, Jeffrey H Newcorn, Kevin M Antshel, Lenard Adler, Kurt Roots, Monika Heller
OBJECTIVE: The purpose of this study was to assess the relative accuracies of the Conners' Brief Rating Scale, Parent Version, the Conners' Continuous Performance Test II (CPT II), and a novel interactive game called "Groundskeeper" to discriminate child psychiatric patients with and without attention-deficit/hyperactivity disorder (ADHD). METHODS: We administered the three assessments to 113 clinically referred ADHD and non-ADHD patients who had been diagnosed with the Kiddie-Schedule of Affective Disorders and Schizophrenia- Present and Lifetime (K-SADS-PL), Version 19...
October 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/27090742/counter-striking-psychosis-commercial-video-games-as-potential-treatment-in-schizophrenia-a-systematic-review-of-neuroimaging-studies
#20
REVIEW
Claudia Suenderhauf, Anna Walter, Claudia Lenz, Undine E Lang, Stefan Borgwardt
Schizophrenia is a severe, chronic, and strongly disabling neuropsychiatric disorder, characterized by cognitive decline, positive and negative symptoms. Positive symptoms respond well to antipsychotic medication and psycho-social interventions, in contrast to negative symptoms and neurocognitive impairments. Cognitive deficits have been linked to a poorer outcome and hence specific cognitive remediation therapies have been proposed. Their effectiveness is nowadays approved and neurobiological correlates have been reconfirmed by brain imaging studies...
September 2016: Neuroscience and Biobehavioral Reviews
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