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post-ERCP pancreatitis

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https://www.readbyqxmd.com/read/29156495/multicenter-study-of-endoscopic-preoperative-biliary-drainage-for-malignant-hilar-biliary-obstruction-e-pod-hilar-study
#1
Yousuke Nakai, Ryuichi Yamamoto, Masato Matsuyama, Yuji Sakai, Yukiko Takayama, Jun Ushio, Yukiko Ito, Katsuya Kitamura, Shomei Ryozawa, Tsunao Imamura, Kouhei Tsuchida, Jo Hayama, Takao Itoi, Yoshiaki Kawaguchi, Yu Yoshida, Kazuya Sugimori, Kenji Shimura, Masafumi Mizuide, Tomohisa Iwai, Ko Nishikawa, Hiroshi Yagioka, Masatsugu Nagahama, Nobuo Toda, Tomotaka Saito, Ichiro Yasuda, Kenji Hirano, Osamu Togawa, Kenji Nakamura, Iruru Maetani, Naoki Sasahira, Hiroyuki Isayama
BACKGROUND AND AIM: Endoscopic nasobiliary drainage (ENBD) is often recommended in preoperative biliary drainage (PBD) for hilar malignant biliary obstruction (MBO) but endoscopic biliary stent (EBS) is also used in the clinical practice. We conducted this large scale multicenter study to compare ENBD and EBS in this setting. METHODS: A total of 374 cases undergoing PBD including 281 ENBD and 76 EBS for hilar MBO in 29 centers were retrospectively studied. RESULTS: Extrahepatic cholangiocarcinoma (ECC) accounted for 69...
November 20, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29154236/risk-factors-of-pancreatitis-after-endoscopic-sphincterotomy-review-of-literature-and-practical-remarks-based-on-approximately-10-000-ercps
#2
Andrzej Jamry
Post-endoscopic pancreatitis (PEP) is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). Depending on the presence of risk factors, PEP can occur in 4,1% to about 43% of patients. According to the European Society of Gastrointestinal Endoscopy (ESGE) guidelines, only three to patient-associated risk factors have been identified: suspected sphincter of Oddi dysfunction (SOD) (OR 4.09), female gender (OR 2.23), and previous pancreatitis (OR 2.46). Another three procedure-associated factors include cannulation attempt duration > 10 minutes (OR 1...
October 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/29124124/preliminary-experience-with-pancreatic-sphincterotomy-as-treatment-for-intraductal-papillary-mucinous-neoplasm-associated-recurrent-pancreatitis
#3
Laura Bernardoni, Stefano Francesco Crinò, Giorgia De Conti, Maria Cristina Conti Bellocchi, Nicolò De Pretis, Antonio Amodio, Luca Frulloni, Armando Gabbrielli
Background and study aims:  Pancreatic intraductal papillary mucinous neoplasms (IPMN) are cystic tumors of the pancreas characterized by a malignant potential. IPMN have been associated with recurrent pancreatitis (RP). Obstruction of the main pancreatic duct by thick mucus has been postulated to be the cause of pancreatitis. In a few isolated reports, pancreatic sphincterotomy (PS) has been reported to reduce the frequency of pancreatitis. The aim of this study was to assess the efficacy of PS in patients with IPMN-associated RP...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29117728/different-pattern-of-risk-factors-for-post-ercp-pancreatitis-in-patients-with-biliary-stricture
#4
Liang Zheng, Xiangping Wang, Qin Tao, Shuhui Liang, Biaoluo Wang, Hui Luo, Rongchun Zhang, Liyue Zheng, Shengye Yang, Jie Chen, Yanglin Pan, Xuegang Guo
OBJECTIVE: To identify possible risk factors associated with post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in biliary stricture (BS), common bile duct stone (CBDS) and unselected patients. MATERIALS AND METHODS: Consecutive ERCP patients with native papilla from January 2010 to December 2014 in Xijing Hospital were eligible. Patient-related and procedure-related parameters were collected retrospectively. The primary outcome was PEP...
November 9, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29096689/rectally-administered-indomethacin-to-prevent-post-eswl-pancreatitis-ripep-study-protocol-for-a-randomized-controlled-trial
#5
Yang-Yang Qian, Hui Chen, Xin-Ying Tang, Xi Jiang, Wei Qian, Wen-Bin Zou, Lei Xin, Bo Li, Yan-Fen Qi, Liang-Hao Hu, Duo-Wu Zou, Zhen-Dong Jin, Dong Wang, Yi-Qi Du, Luo-Wei Wang, Feng Liu, Zhao-Shen Li, Zhuan Liao
BACKGROUND: Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is the first-line therapy for large pancreatic duct stones. Although it is a highly effective and safe procedure for the fragmentation of pancreatic stones, it is still not complication-free. Just like endoscopic retrograde cholangiopancreatography (ERCP), pancreatitis is the most common complication. To date, nonsteroidal anti-inflammatory drugs (NSAIDs) have proven to be the only effective prophylactic medication for post-ERCP pancreatitis and the European, American and Japanese Society for Gastrointestinal Endoscopy guidelines have recommended prophylactic rectally administered indomethacin for all patients undergoing ERCP...
November 2, 2017: Trials
https://www.readbyqxmd.com/read/29093587/-efficacy-and-complications-of-double-guidewire-technique-in-biliary-tract-cannulation
#6
Edson Guzmán-Calderón, Augusto Vera, Ramiro Díaz, Edgar Alva, Ronald Arcana
OBJECTIVE: To determine the efficacy and safety of double guidewire technique in patients with difficult biliary cannulation during ERCP. MATERIALS AND METHODS: We conducted a retrospective cohort study of all ERCPs performed between January 2015 and July 2016. DGT was performed in patients for whom biliary cannulation was difficult and guidewire insertion into the pancreatic duct (PD) was inadvertently achieved while attempting the standard WGC technique. RESULTS: 24 patients were enrolled with ERCP and DGT; 17 were female (70...
July 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29093393/retroperitoneal-perforation-caused-by-migration-of-a-pancreatic-spontaneous-dislodgement-stent-into-periampullary-diverticula
#7
Masatake Nishiwaki, Chiemi Mizuno, Kota Yano, Hirohisa Oya, Ichiro Amano, Junko Matsumoto, Izumi Tanaka, Naoki Sawai, Masayuki Mizuno, Toshihide Shima, Yoshiharu Miyamoto, Takeshi Okanoue
An 85-year-old woman underwent endoscopic retrograde cholangiopancreatography (ERCP) for obstructive jaundice. Selective bile duct cannulation was unsuccessful because of periampullary diverticula (PAD). A pancreatic spontaneous dislodgement stent (PSDS) (5F diameter, 3 cm, straight type) was inserted to prevent post-ERCP pancreatitis. Three days after ERCP, she complained of abdominal pain, and computed tomography revealed retroperitoneal perforation because of PSDS migration to the PAD. If the papillary orifice is observed at the diverticular rim or in the diverticula, a pigtailed PSDS on the duodenal side or flanged stent on the pancreatic ductal side should be inserted in order to prevent this rare adverse event...
November 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29090241/multicenter-retrospective-and-comparative-study-of-5-minute-versus-15-second-endoscopic-papillary-balloon-dilation-for-removal-of-bile-duct-stones
#8
Ryunosuke Hakuta, Tsuyoshi Hamada, Yousuke Nakai, Hiroyuki Isayama, Hirofumi Kogure, Suguru Mizuno, Takahara Naminatsu, Hiroshi Yagioka, Osamu Togawa, Saburo Matsubara, Yukiko Ito, Natsuyo Yamamoto, Takeshi Tsujino, Kazuhiko Koike
BACKGROUND AND STUDY AIMS:  Endoscopic papillary balloon dilation (EPBD) is a method of bile duct stone removal that has a better long-term outcome but a high risk of post-ERCP pancreatitis (PEP). Recent studies have suggested that 5-minute EPBD can reduce the incidence of PEP. This study aimed to examine the safety and effectiveness of longer duration EPBD compared with shorter duration EPBD (5 minutes vs. 15 seconds after disappearance of the waist of a dilation catheter). PATIENTS AND METHODS:  Patients without a history of endoscopic sphincterotomy or EPBD who underwent EPBD to remove bile duct stones were selected retrospectively from five centers...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29062479/murine-genotype-impacts-pancreatitis-severity-and-systemic-inflammation-an-experimental-study
#9
Gabriel J Seifert, Karoline C Sander, Sabine Richter, Uwe A Wittel
BACKGROUND: Little is known regarding the impact of host response in acute pancreatitis. Here, we induce murine necrotizing pancreatitis in 9 different mouse strains. MATERIALS AND METHODS: We examined 9 different mouse strains: Balb/CB4J, C3H/HEJ, NOD/SHILT, A/J, AKR/J, C57BI/6J, DBA/2J, FVB/NJ, 129S1/SvlmJ. 10 animals per strain were randomly allotted to two groups. Sterile necrotizing pancreatitis was induced by injection of taurocholate into the common bile duct...
December 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29047328/the-modified-pancreatic-stent-system-for-prevention-of-post-ercp-pancreatitis-a-case-control-study
#10
Cheng Zhang, Yu-Long Yang, Yue-Feng Ma, Hong-Wei Zhang, Jing-Yi Li, Mei-Ju Lin, Li-Jun Shi, Chun-Chun Qi
BACKGROUND: Prophylactic pancreatic stents after endoscopic retrograde cholangiopancreatography (ERCP) can help prevent post-ERCP pancreatitis. However most of the pancreatic stents need to be removed by another ERCP. The aim of this observational study was to investigate the feasibility and effectiveness of the modified pancreatic stent system for prevention of post-ERCP pancreatitis. METHODS: From November 2013 to November 2015, a total of 230 patients who had prophylactic pancreatic stent placed for prevention of post-ERCP pancreatitis at a single institution were identified and stratified...
October 18, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29043861/nasobiliary-drainage-can-reduce-the-incidence-of-post-ercp-pancreatitis-after-papillary-large-balloon-dilation-plus-endoscopic-biliary-sphincterotomy-a-randomized-controlled-trial
#11
Qiang Huang, Feng Shao, Chen Wang, Wei Qi, Lu Jun Qiu, Zheng Liu
BACKGROUND AND AIMS: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis can be reduced following endoscopic papillary balloon dilation with the placement of an endoscopic nasobiliary drainage (ENBD) catheter. The aim of this study was to determine whether the placement of an ENBD reduces the risk of post-ERCP pancreatitis following endoscopic papillary large balloon dilation together with endoscopic biliary sphincterotomy. METHODS: A total of 160 patients with bile duct stones were randomly assigned (1:1) to an ENBD group or no-ENBD group...
October 18, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29032692/a-post-endoscopic-retrograde-cholangiopancreatography-subcapsular-hepatic-hematoma
#12
Rocío Soler Humanes, Miguel Ángel Suárez Muñoz, Blanca García García
Nowadays endoscopic retrograde cholangiopancreatography (ERCP) is a minimally invasive technique with a complication rate around 2.5% in expert hands, being the most frequent: acute pancreatitis, cholangitis, hemorrhage and perforation. An exceptional complication is subcapsular hepatic hematoma, first published in the literature in 2000, with few cases reported. Regarding the case published by Del Moral Martínez et al (Hepatic Hematoma after ERCP: presentation of two new cases. Rev Esp Enferm Dig 2017, Vol...
November 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29020689/transpancreatic-precut-papillotomy-versus-double-guidewire-technique-in-difficult-biliary-cannulation-prospective-randomized-study
#13
Harutoshi Sugiyama, Toshio Tsuyuguchi, Yuji Sakai, Rintaro Mikata, Shin Yasui, Yuto Watanabe, Dai Sakamoto, Masato Nakamura, Takao Nishikawa
Background and study aims Difficult biliary cannulation and unintentional pancreatic duct cannulation are thought to be important contributors to pancreatitis occurring after endoscopic retrograde cholangiopancreatography. Our aim was to compare and evaluate the rates of success and complications of transpancreatic precut papillotomy (TPPP) and the double-guidewire technique (DGT), both with prophylactic pancreatic stenting. Patients and methods From April 2011 to March 2014, patients with difficult biliary cannulation, in whom we planned to first position a guidewire in the pancreatic duct, were enrolled, and 68 patients were prospectively randomly allocated to two groups (TPPP 34, DGT 34)...
October 11, 2017: Endoscopy
https://www.readbyqxmd.com/read/28966682/prophylactic-ulinastatin-administration-for-preventing-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis-a-meta-analysis
#14
Kun Zhu, Jian-Ping Wang, Jin-Gen Su
The objective of the present study was to perform a meta-analysis of all available studies on the effect of prophylactic ulinastatin administration on preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). The PubMed, Web of Knowledge and Chinese National Knowledge Infrastructure databases were searched to identify all relevant studies published in English or Chinese prior to April 2016. Cochrane Review Manager was used to calculate the pooled risk ratio (RR) and 95% confidence interval (CI) to determine the effect of prophylactic ulinastatin on PEP, post-ERCP hyperamylasemia (PEHA) and post-ERCP abdominal pain...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28964747/safety-and-efficacy-of-early-feeding-based-on-clinical-assessment%C3%A2-at-4-hours-after-ercp-a-prospective-randomized%C3%A2-controlled-trial
#15
Chan Hyuk Park, Jang Han Jung, Bomi Hyun, Hye Ji Kan, Jin Lee, Sea Hyub Kae, Hyun Joo Jang, Dong Hee Koh, Min Ho Choi, Moon Jae Chung, Seungmin Bang, Se Woo Park
BACKGROUND AND AIMS: The optimal timing of refeeding after ERCP is unknown. Some practices keep the patient fasting for 24 hours after ERCP, whereas others resume feeding earlier. We aimed to evaluate the risk of post-ERCP pancreatitis (PEP) in patients who initiate early feeding, based on their clinical assessment, including serum amylase testing performed at 4 hours after ERCP. METHODS: Patients who were scheduled for ERCP were recruited. Patients without abdominal pain and tenderness and a serum amylase level within 1...
September 28, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28960034/prediction-of-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis-using-4-hour-post-endoscopic-retrograde-cholangiopancreatography-serum-amylase-and-lipase-levels
#16
Yeon Kyung Lee, Min Jae Yang, Soon Sun Kim, Choong Kyun Noh, Hyo Jung Cho, Sun Gyo Lim, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim
Early post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) prediction may allow safe same-day outpatients discharge after ERCP and earlier proper management. This study aimed to assess the usefulness of the 4-hour post-ERCP serum amylase and lipase levels for PEP early prediction and to investigate predictive cut-off values for 4-hour post-ERCP serum amylase and lipase levels for safe discharge and urgent initiation of resuscitation. The data of 516 consecutive patients with native papilla who underwent ERCP between January 2013 and August 2014 were retrospectively reviewed...
November 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28937025/the-efficacy-and-safety-of-the-left-lateral-position-for-endoscopic-retrograde-cholangiopancreatography
#17
Tae Young Park, Sang Hyeon Choi, Young Joo Yang, Suk Pyo Shin, Chang Seok Bang, Ki Tae Suk, Gwang Ho Baik, Dong Joon Kim
BACKGROUND/AIM: Endoscopic retrograde cholangiopancreatography (ERCP) is typically performed in prone position. In cases of difficulty in prone position, ERCP can be performed in left lateral position. We aimed to evaluate the efficacy and safety of left lateral position for ERCP compared with those of prone position. PATIENTS AND METHODS: Between August 2015 and March 2016, a total of 62 patients with native papilla who underwent ERCP were randomly assigned to undergo the procedure in left lateral position (n = 31) or prone position (n = 31)...
September 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28916891/a-prospective-randomized-study-of-loop-tip-versus-straight-tip-guidewire-in-wire-guided-biliary-cannulation
#18
Jae Chul Hwang, Byung Moo Yoo, Min Jae Yang, Yeon Kyung Lee, Ju Young Lee, Kihyun Lim, Choong-Kyun Noh, Hyo Jung Cho, Soon Sun Kim, Jin Hong Kim
BACKGROUND: Wire-guided cannulation has been widely accepted as a useful technique for achieving selective biliary access because it has significantly increased the success rate of biliary cannulation compared with conventional contrast-assisted cannulation. Unlike conventional guidewires with a straight tip, a loop-tip guidewire (LGW) has a closed distal loop that may facilitate less traumatic access through the epithelial folds of the intra-duodenal biliary segments. The aim of this study was to compare the performance of a LGW with a straight-tip guidewire (SGW) in achieving successful selective biliary cannulation...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28898571/risk-factors-of-post-ercp-pancreatitis-in-biliary-type-sphincter-of-oddi-dysfunction-in-japanese-patients
#19
Hiroyuki Miyatani, Satohiro Matsumoto, Hirosato Mashima
OBJECTIVES: Suspected sphincter of Oddi dysfunction (SOD) is a well-known risk factor for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). The indication of ERCP for suspected SOD patients was very low in Japan compared to other countries. Therefore, the risk of PEP may be different in Japanese SOD patients. The objective of this study was to evaluate the risk of PEP in suspected biliary type SOD in Japan. METHODS: From December 1996 to January 2017, 72 patients were suspected to have biliary type SOD by questionnaire, liver function tests, hepatobiliary scintigraphy, abdominal ultrasonography, upper gastrointestinal endoscopy, endoscopic ultrasonography, and magnetic resonance cholangiopancreatography...
September 12, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28866457/randomized-trial-of-cholangioscopy-guided-laser-lithotripsy%C3%A2-versus-conventional-therapy-for-large-bile-duct%C3%A2-stones-with-videos
#20
James Buxbaum, Ara Sahakian, Christopher Ko, Preeth Jayaram, Christianne Lane, Chung Yao Yu, Ravi Kankotia, Loren Laine
BACKGROUND AND AIMS: Bile duct stones >1 cm have a decreased incidence of successful endoscopic extraction and often require lithotripsy. Although previous guidelines suggested mechanical lithotripsy for large common bile duct stones, current guidelines suggest cholangioscopy-guided lithotripsy as an adjunct with or without balloon dilation or mechanical lithotripsy. However, no randomized trials have assessed the usefulness of this practice. METHODS: Patients with bile duct stones >1 cm in diameter were randomized in a 2:1 ratio to cholangioscopy-guided laser lithotripsy versus conventional therapy only...
September 1, 2017: Gastrointestinal Endoscopy
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