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https://www.readbyqxmd.com/read/29151273/post-treatment-with-methylene-blue-is-effective-against-delayed-encephalopathy-after-acute-carbon-monoxide-poisoning
#1
Ningjun Zhao, Pengchong Liang, Xiaoying Zhuo, Chenglei Su, Xuemei Zong, Bingnan Guo, Han Dong, Xianliang Yan, Shuqun Hu, Quanguang Zhang, Xu Tie
Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) is the most severe and clinically intractable complication that occurs following acute carbon monoxide poisoning. Unfortunately, the mechanism of DEACMP is still vague. Growing evidence indicates that delayed cerebral damage following CO poisoning is related to oxidative stress, abnormal neuro-inflammation, apoptosis and immune-mediated injury. Our recent report indicated that methylene blue (MB) may be a promising therapeutic agent in the prevention of neuronal cell death and cognitive deficits following transient global cerebral ischaemia (GCI)...
November 19, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29151232/early-promising-outcome-following-arthroscopic-implantation-of-the-subacromial-balloon-spacer-for-treating-massive-rotator-cuff-tear
#2
R S M Piekaar, I C E Bouman, P M van Kampen, F van Eijk, P E Huijsmans
BACKGROUND: Massive rotator cuff tear (RCT) can result in disability and severe pain. When conservative treatment fails, surgical treatment should be considered, as various surgical options can provide relatively satisfactory results. However, choosing an optimal treatment remains controversial. A relatively new treatment for irreparable RCT is the arthroscopic implantation of a biodegradable balloon spacer into the subacromial space. Here, we examined whether placement of this balloon spacer reduces pain and improves functional outcome in patients with an irreparable RCT...
November 18, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29151228/previously-implanted-intra-peritoneal-mesh-increases-morbidity-during-re-laparoscopy-a-retrospective-case-matched-cohort-study
#3
A Sharma, P Chowbey, N S Kantharia, M Baijal, V Soni, R Khullar
PURPOSE: Laparoscopic ventral hernia repair (LVHR) with intra-peritoneal mesh placement is standard surgical treatment of abdominal wall hernias. During laparoscopic re-intervention, we examined adhesions that develop after previous intra-peritoneal mesh placement and ascertained morbidity and risk of adverse events. METHODS: This is a retrospective, case-matched comparison of three patient groups-previous intra-peritoneal mesh (Group A), previous abdominal surgery (Group B) and no previous abdominal surgery (Group C)...
November 18, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29151182/electrical-cardioversion-of-patients-with-implanted-pacemaker-or-cardioverter-defibrillator-results-of-a-survey-of-german-centers-and-systematic-review-of-the-literature
#4
J Lüker, A Sultan, T Plenge, J van den Bruck, C-H Heeger, S Meyer, K Mischke, R R Tilz, D Vollmann, G Nölker, B Schäffer, S Willems, D Steven
AIMS: A relevant number of patients presenting for electrical cardioversion carry a pacemaker (PM) or ICD. Case reports suggest a potential hazard of external cardioversion/defibrillation. The incidence of shock related device complications is unknown. No guidelines or recommendations by international medical societies for a cardioversion protocol of cardiovascular implantable electronic device (CIED) patients exist. We conducted a nationwide survey to gather real-world clinical data on the current clinical approach towards these patients during electrical cardioversion and to estimate the incidence of shock-related complications...
November 18, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29151166/t2-weighted-images-are-superior-to-other-mr-image-types-for-the-determination-of-diffuse-intrinsic-pontine-glioma-intratumoral-heterogeneity
#5
Stephen Harward, S Harrison Farber, Michael Malinzak, Oren Becher, Eric M Thompson
PURPOSE: Diffuse intrinsic pontine glioma (DIPG) remains the main cause of death in children with brain tumors. Given the inefficacy of numerous peripherally delivered agents to treat DIPG, convection enhanced delivery (CED) of therapeutic agents is a promising treatment modality. The purpose of this study was to determine which MR imaging type provides the best discrimination of intratumoral heterogeneity to guide future stereotactic implantation of CED catheters into the most cellular tumor regions...
November 18, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29151130/layered-pegda-hydrogel-for-islet-of-langerhans-encapsulation-and-improvement-of-vascularization
#6
Giulia Marchioli, Lisa Zellner, Catarina Oliveira, Marten Engelse, Eelco de Koning, Joao Mano, Karperien, Aart van Apeldoorn, Lorenzo Moroni
Islets of Langerhans need to maintain their round morphology and to be fast revascularized after transplantation to preserve functional insulin secretion in response to glucose stimulation. For this purpose, a non-cell-adhesive environment is preferable for their embedding. Conversely, nutrient and oxygen supply to islets is guaranteed by capillary ingrowth within the construct and this can only be achieved in a matrix that provides adhesion cues for cells. In this study, two different approaches are explored, which are both based on a layered architecture, in order to combine these two opposite requirements...
November 18, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29151032/elevated-baseline-serum-fibrinogen-effect-on-2-year-major-adverse-cardiovascular-events-following-percutaneous-coronary-intervention
#7
Lawrence Ang, Omid Behnamfar, Samhita Palakodeti, Felice Lin, Ali Pourdjabbar, Mitul P Patel, Ryan R Reeves, Ehtisham Mahmud
BACKGROUND: Elevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown. METHODS AND RESULTS: Baseline demographics and 2-year MACE were recorded among subjects undergoing nonemergent percutaneous coronary intervention. A total of 332 subjects (66.6±19.5 years, 69.9% male, 25.3% acute coronary syndrome) were enrolled. Two-year MACE (periprocedural myocardial infarction 9...
November 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29150957/randomized-controlled-clinical-two-center-study-using-xenogeneic-block-grafts-loaded-with-recombinant-human-bone-morphogenetic-protein-2-or-autogenous-bone-blocks-for-lateral-ridge-augmentation
#8
Daniel S Thoma, Michael Payer, Norbert Jakse, Stefan P Bienz, Jürg Hüsler, Patrick R Schmidlin, Ui-Won Jung, Christoph H F Hämmerle, Ronald E Jung
OBJECTIVES: to test whether or not the use of a xenogeneic block loaded with recombinant human bone morphogenetic protein-2 (rhBMP-2) results in different bone quantity and quality compared to an autogenous bone block. MATERIALS AND METHODS: 24 patients with insufficient bone volume for implant placement were randomly assigned to two treatment modalities: a xenogeneic bone block loaded with rhBMP-2 (test) or an autogenous bone block (control). The horizontal ridge width was evaluated prior to augmentation, after augmentation and at 4 months...
November 18, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29150670/ultrahigh-field-mr-imaging-of-a-subconjunctival-anti-glaucoma-drug-delivery-system-in-a-rabbit-model
#9
Franziska Kopp, Thomas Eickner, Stefan Polei, Karen Falke, Martin Witt, Niels Grabow, Oliver Stachs, Rudolf F Guthoff, Tobias Lindner
Local drug delivery systems (DDS) have become a favourable approach for the treatment of numerous diseases. Biomedical imaging techniques such as ultrahigh field magnetic resonance imaging (UHF-MRI) offer unique insight into DDS biodegradation in vivo. We describe the establishment of a 7 Tesla MRI routine for longitudinal in vivo examinations of a subconjunctival DDS for the treatment of glaucoma in a rabbit model. In initial in vitro examinations the T2-relaxation times of the polymeric DDS components were assessed...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150639/in-vitro-maturation-and-in-vivo-integration-and-function-of-an-engineered-cell-seeded-disc-like-angle-ply-structure-daps-for-total-disc-arthroplasty
#10
J T Martin, S E Gullbrand, D H Kim, K Ikuta, C G Pfeifer, B G Ashinsky, L J Smith, D M Elliott, H E Smith, R L Mauck
Total disc replacement with an engineered substitute is a promising avenue for treating advanced intervertebral disc disease. Toward this goal, we developed cell-seeded disc-like angle ply structures (DAPS) and showed through in vitro studies that these constructs mature to match native disc composition, structure, and function with long-term culture. We then evaluated DAPS performance in an in vivo rat model of total disc replacement; over 5 weeks in vivo, DAPS maintained their structure, prevented intervertebral bony fusion, and matched native disc mechanical function at physiologic loads in situ...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150533/disparity-between-indications-for-and-utilization-of-implantable-cardioverter-defibrillators-in-asian-patients-with-heart-failure
#11
Yvonne May Fen Chia, Tiew-Hwa Katherine Teng, Eugene S J Tan, Wan Ting Tay, A Mark Richards, Calvin Woon Loong Chin, Wataru Shimizu, Sang Weon Park, Chung-Lieh Hung, Lieng H Ling, Tachapong Ngarmukos, Razali Omar, Bambang B Siswanto, Calambur Narasimhan, Eugene B Reyes, Cheuk-Man Yu, Inder Anand, Michael R MacDonald, Jonathan Yap, Shu Zhang, Eric A Finkelstein, Carolyn S P Lam
BACKGROUND: Implantable cardioverter defibrillators (ICDs) are lifesaving devices for patients with heart failure (HF) and reduced ejection fraction. However, utilization and determinants of ICD insertion in Asia are poorly defined. We determined the utilization, associations of ICD uptake, patient-perceived barriers to device therapy and, impact of ICDs on mortality in Asian patients with HF. METHODS AND RESULTS: Using the prospective ASIAN-HF (Asian Sudden Cardiac Death in Heart Failure) registry, 5276 patients with symptomatic HF and reduced ejection fraction (HFrEF) from 11 Asian regions and across 3 income regions (high: Hong Kong, Japan, Korea, Singapore, and Taiwan; middle: China, Malaysia, and Thailand; and low: India, Indonesia, and Philippines) were studied...
November 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29150521/telephone-counselling-for-subdermal-implants-and-intrauterine-contraceptives
#12
Caitlin D Gorman, Joanne Dennis, Jennifer A Heathcote
No abstract text is available yet for this article.
November 17, 2017: Journal of Family Planning and Reproductive Health Care
https://www.readbyqxmd.com/read/29150326/concomitant-mitral-valve-procedures-in-patients-undergoing-implantation-of-continuous-flow-left-ventricular-assist-devices-an-intermacs-database-analysis
#13
Jason O Robertson, David C Naftel, Susan L Myers, Ryan J Tedford, Susan M Joseph, James K Kirklin, Scott C Silvestry
BACKGROUND: Management of existing mitral valve (MV) disease in patients undergoing left ventricular assist device (LVAD) implantation remains controversial. METHODS: Among continuous-flow LVAD patients with moderate to severe mitral regurgitation entered into the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database between April 2008 and March 2014 (n = 4,930), outcomes were compared between patients who underwent MV repair (MVr, n = 252), MV replacement (MVR, n = 11) and no MV procedure (no MVP, n = 4,667)...
October 10, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29150321/a-description-of-the-sequence-of-long-term-behavior-of-autogenous-boneblock-in-maxillary-sinus-augmentation-in-sheep-additional-morphologic-and-histomorphometric-evidence
#14
Sebastian Pohl, Robert Haas, Stefan Tangl, Christian Schuh, Georg Mailath-Pokorny, Veronika Pohl
OBJECTIVE: To document the behavior of autogenous bone block in sinus lift and surgical consequences. STUDY DESIGN: Twelve sinus lifts with autogenous hip bone blocks and simultaneous insertion of two implants in 6 adult female sheep. Polychrome sequential labelling and histologic and histomorphometric evaluation after 6, 16, and 26 weeks. RESULTS: Augmentation material in the apical third was almost fully resorbed after 26 weeks (P = ...
September 21, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29150150/biocompatible-hollow-polymeric-particles-produced-by-a-mild-solvent-and-template-free-strategy
#15
Eustolia Rodríguez-Velázquez, Pablo Taboada, Manuel Alatorre-Meda
Macroscopic hollow polymeric particles are attractive materials for various applications such as surgery, food industry, agriculture, etc. However, protocols reporting their synthesis have hitherto made use of organic solvents and/or sacrificial templates, compromising the encapsulation of different bioactive compounds and the process yield. Here, millimeter-size, hollow polymeric particles were synthesized, for the first time, in a solvent- and template free manner onto superhydrophobic surfaces (SHS). The particles were produced upon assembly and double superficial crosslinking of liquid droplets of DNA and methacrylamide chitosan aqueous solutions (CH:MA), leading to liquid-core particles with a hardened hydrogel shell...
November 14, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29150131/a-3d-printed-guide-for-lateral-approach-sinus-grafting-a-dental-technique
#16
Brian J Goodacre, Rajesh S Swamidass, Jaime Lozada, Aladdin Al-Ardah, Erik Sahl
Lateral approach sinus grafting has become a routine and predictable surgical method of augmenting the pneumatized sinus for implant placement. Outlining the lateral window access can be a challenging task for the clinician to envision and execute. Improper extension and access to the maxillary sinus can prevent proper placement of graft materials and lead to complications. The purpose of this report was to demonstrate a technique that will allow the precise planning of the lateral approach using radiographic information and 3-dimensional (3D) software to 3D-print a surgical guide...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29150129/diagnostic-accuracy-of-4-intraoral-radiographic-techniques-for-misfit-detection-at-the-implant-abutment-joint
#17
Pollyana Darós, Vinícius Cavalcanti Carneiro, Amanda Pasolini Siqueira, Sergio Lins de-Azevedo-Vaz
STATEMENT OF PROBLEM: A misfit or gap at the implant-abutment joint (IAJ) requires detection as it may compromise the health of the peri-implant tissue. However, which radiographic technique provides the most orthogonal relationship between the central beam and the implant/image receptor is unclear. PURPOSE: The purpose of this in vitro study was to evaluate the diagnostic accuracy of 4 intraoral radiographic techniques on misfit detection at the IAJ. MATERIAL AND METHODS: Twenty implants were placed in polyamide jaws, and customized dental implant abutments with a metal collar were installed...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29150019/definitive-abutments-probably-result-in-minimal-decrease-in-bone-loss-and-buccal-gingival-recession-compared-with-traditional-implants
#18
Romina Brignardello-Petersen
No abstract text is available yet for this article.
November 11, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29149978/perioperative-prophylaxis-for-total-artificial-heart-transplantation
#19
H E Chambers, P Pelish, F Qiu, D F Florescu
BACKGROUND: Practice variation regarding perioperative antimicrobial prophylaxis in total artificial heart transplantations (TAH-t) across institutions is unknown. The aim of our survey was to assess the current practices for prevention of infection in TAH-t recipients among different programs. METHODS: An electronic survey was sent to programs that implant Syncardia TAH (Syncardia Systems, Tuscon, Ariz, USA). Proportions were analyzed for categorical variables; means and SDs were analyzed for continuous variables...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149972/right-extended-split-liver-transplantation-compared-with-whole-liver-transplantation-lessons-learned-at-a-single-center-in-latin-america-results-from-a-match-case-control-study
#20
S E Gambaro, P Romero, N Pedraza, L Moulin, S Yantorno, D Ramisch, C Rumbo, P Barros-Schelotto, V Descalzi, G E Gondolesi
BACKGROUND: Despite the progressively increasing gap between patients waiting for liver transplant under the Model for End-stage Liver Disease MELD system and the availability of deceased donor organs, the use of right extended split liver grafts (RESLG) has not been accepted by all centers. In this study, we compared the results obtained using RESLG vs a group of matched whole liver graft (WLG) recipients at a single center in Latin America. METHODS: A single-center retrospective review performed between August 2009 and December 2015...
November 2017: Transplantation Proceedings
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