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https://www.readbyqxmd.com/read/29034563/heart-failure-study-of-multipoint-pacing-effects-on-ventriculoarterial-coupling-rationale-and-design-of-the-humvee-trial
#1
Christina Chrysohoou, Polychronis Dilaveris, Christos-Konstantinos Antoniou, Ioannis Skiadas, Konstantinos Konstantinou, Konstantinos Gatzoulis, Ioannis Kallikazaros, Dimitrios Tousoulis
Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. The aim of this study is to compare the effects of MPP against those of standard biventricular pacing (BVP) on (i) ventriculoarterial coupling (VAC) and energy efficiency of the failing heart, (ii) diastolic function, (iii) quality of life, and (iv) NT-proBNP levels and glomerular filtration rate (GFR) during a follow-up of 13 months...
October 15, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29034039/histological-reactions-and-the-in-vivo-patency-rates-of-small-silk-vascular-grafts-in-a-canine-model
#2
Makoto Haga, Satoshi Yamamoto, Hiroyuki Okamoto, Katsuyuki Hoshina, Tetsuro Asakura, Toshiaki Watanabe
Objective: To evaluate in vivo patency rates of silk fibroin (SF) vascular grafts and resulting histological reactions in a canine model. Methods: To generate 3.5-mm inner diameter vessels, a combination of plaited silk fibers were wound with cocoon filaments and subsequently coated with an SF solution. The resulting SF grafts (n=35) were implanted into the carotid arteries of male beagles (age, 1-2 years; body weight: 9.0-10.5 kg). Expanded polytetrafluoroethylene (4-mm inner diameter, ePTFE) grafts (n=5) were used as controls...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033509/predictors-of-impaired-reperfusion-after-percutaneous-coronary-intervention-in-patients-with-in-hospital-acute-stent-thrombosis-a-retrospective-analyses-of-5-years-of-data
#3
Burak Açar, Orhan Maden, Kevser Gülcihan Balci, Sefa Ünal, Mustafa Mücahit Balci, Esra İpek Gücük, Meryem Kara, Hatice Selcuk, Mehmet Timur Selcuk
BACKGROUND: Acute stent thrombosis (STh) is a rare complication of percutaneous coronary intervention (PCI) and is associated with a high-risk of reperfusion failure. However, data focusing on risk factors of reperfusion failure in patients undergoing repeat PCI for treatment of STh remains inadequate. METHODS: A total of 8815 patients who underwent PCI with stent implantation from January 2009 to December 2013 were retrospectively reviewed. Among those cases, patients that presented with acute STh and underwent a repeat PCI for acute STh were identified...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033157/midterm-survivorship-after-revision-total-hip-arthroplasty-with-a-custom-triflange-acetabular-component
#4
Brian P Gladnick, Keith A Fehring, Susan M Odum, Michael J Christie, David K DeBoer, Thomas K Fehring
BACKGROUND: Custom triflange acetabular components are being increasingly used for the reconstruction of Paprosky type IIIB acetabular defects. However, midterm survivorship data are lacking. METHODS: We queried the prospective registries at 2 high-volume revision centers for patients who had undergone revision total hip arthroplasty using a custom triflange component between 2000 and 2011. We identified 73 patients with minimum 5-year follow-up. These patients' records were reviewed to determine incidence of revision or reoperation, clinical performance, and radiographic stability...
September 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29032860/biomechanical-comparison-of-two-different-locking-plates-for-open-wedge-high-tibial-osteotomy
#5
Nienke van Egmond, Dennis Janssen, Gerjon Hannink, Nico Verdonschot, Albert van Kampen
BACKGROUND: The purpose of this study was to compare the mechanical stability of a relatively thin locking plate (FlexitSystem implant) with a relatively firm locking plate (TomoFix implant), both used for opening wedge high tibial osteotomy. METHODS: Seven fresh frozen paired human cadaveric tibiae were used. The opening wedge high tibial osteotomies in the left tibiae were fixated with the FlexitSystem implant and in the right tibiae with the TomoFix implant. The tibiae were CT-scanned to determine the bone mineral density...
October 9, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29032854/intrasinusal-locking-technique-a-novel-use-of-the-ring-block-technique-at-sinus-perforations-for-simultaneous-implant-placement
#6
A Sindel, M M Özarslan, Ö Özalp
Ten patients who underwent sinus lift surgery with simultaneous implant placement using the intrasinusal locking technique were evaluated retrospectively. All patients were scheduled for sinus floor elevation procedures with simultaneous implant placement. Schneiderian membrane perforation occurred during the lifting procedure, and conventional methods failed to repair the perforation. Therefore, an autogenous bone ring was placed at the base of the maxillary sinus and was locked to the alveolar crest with a dental implant...
October 9, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29032583/third-generation-ventricular-assist-device-mid-term-outcomes-of-the-heartware-hvad-in-pediatric-patients
#7
Mustafa Pac, Sinan Sabit Kocabeyoglu, Umit Kervan, Dogan Emre Sert, Serhat Koca, Ibrahim Ece, Feyza Aysenur Pac
The HeartWare HVAD is a small, third generation continuous flow pump that is intracorporeally placed for support of a failing ventricle in adult patients. This device is small in size when compared to other left ventricular assist devices and can therefore be used in smaller sized pediatric patients. We present our initial experience using the HVAD as a bridge to heart transplantation in the pediatric population. We performed a retrospective, single center, nonrandomized review of 17 pediatric patients who underwent HVAD implantation between June 2013 and March 2016...
October 15, 2017: Artificial Organs
https://www.readbyqxmd.com/read/29032313/influence-of-platform-diameter-in-the-reliability-and-failure-mode-of-extra-short-dental-implants
#8
Dimorvan Bordin, Edmara T P Bergamo, Estevam A Bonfante, Vinicius P Fardin, Paulo G Coelho
PURPOSE: To evaluate the influence of implant diameter in the reliability and failure mode of extra-short dental implants. MATERIALS AND METHODS: Sixty-three extra-short implants (5mm-length) were allocated into three groups according to platform diameter: Ø4.0-mm, Ø5.0-mm, and Ø6.0-mm (21 per group). Identical abutments were torqued to the implants and standardized crowns cemented. Three samples of each group were subjected to single-load to failure (SLF) to allow the design of the step-stress profiles, and the remaining 18 were subjected to step-stress accelerated life-testing (SSALT) in water...
September 21, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29031929/permanent-his-bundle-pacing-as-an-alternative-to-biventricular-pacing-for-cardiac-resynchronization-therapy-a-multi-center-experience
#9
Parikshit S Sharma, Gopi Dandamudi, Bengt Herweg, David Wilson, Rajeev Singh, Angela Naperkowski, Jayanthi N Koneru, Kenneth A Ellenbogen, Pugazhendhi Vijayaraman
INTRODUCTION: Cardiac resynchronization therapy (CRT) using biventricular pacing (BVP) is effective in patients with heart failure, bundle branch block (BBB) or right ventricular pacing. Permanent His bundle pacing (HBP) has been reported as an alternative option for CRT. OBJECTIVE: The aim of the study was to assess the feasibility and outcomes of HBP in CRT eligible or failed patients. METHODS: HBP was attempted as a rescue strategy in patients with failed LV lead or non-response to BVP (Group I); or as a primary strategy in patients with AV block, BBB, or high ventricular pacing burden as an alternative to BVP (Group II) in patients with indications for CRT...
October 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29030656/-pyoderma-gangraenosum-after-implantation-of-a-shoulder-endoprothesis
#10
M A Domej, L Pauzenberger, P R Heuberer, W Anderl
Pyoderma gangrenosum is an inflammatory, ulcerative, neutrophilic dermatosis that is clinically characterized by rapidly evolving, painful, necrotic skin lesions. It is typically associated with chronic systemic inflammatory or neoplastic diseases, but may also occur secondary to cutaneous injury or surgery (pathergy). Post-surgical pyoderma gangrenosum typically develops around surgical sites within the immediate postoperative period, mimicking early wound infection. However, common treatment strategies including antibiotics and debridement fail to improve or even worsen symptoms...
October 13, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/29030653/lateral-unicompartmental-knee-replacement-a-systematic-review-of-reasons-for-failure
#11
REVIEW
Lukas Ernstbrunner, Mohamed A Imam, Octavian Andronic, Tabea Perz, Karl Wieser, Sandro F Fucentese
PURPOSE: Currently, individual studies lack the power to successively illustrate different failure modes; therefore, we undertook a systematic review to examine lateral unicompartmental knee replacement (lat UKR) failure modes. Furthermore, we compared early with midterm and late failures and fixed-bearing with mobile-bearing implants. METHODS: A search using the databases of PubMed, EMBASE, Cochrane, and annual registries was performed to search for failed lat UKRs...
October 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29030302/mesenchymal-stem-cell-therapy-for-retro-corneal-membrane-a-clinical-challenge-in-full-thickness-transplantation-of-biosynthetic-corneal-equivalents
#12
Vijayalakshmi Rajendran, Magdalena Netuková, May Griffith, John V Forrester, Lucia Kuffová
Artificial corneas (keratoprostheses) and biosynthetic collagen-based corneal equivalents are surgical implants designed to ease the global burden of corneal blindness. However, keratoprostheses in many cases fail due to development of fibrous retro-corneal membranes (RCM). Fibrous membranes which develop in the anterior chamber after prosthesis implantation do so on a matrix of fibrin. This study investigated fibrin deposition and RCM formation after full-thickness collagen-based hydrogel implants and compared them with syngeneic and allogeneic corneal grafts in mice...
October 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29029105/comparative-performance-of-transcatheter-aortic-valve-in-valve-implantation-versus-conventional-surgical-redo-aortic-valve-replacement-in-patients-with-degenerated-aortic-valve-bioprostheses-systematic-review-and-meta-analysis
#13
Miroslaw Gozdek, Giuseppe Maria Raffa, Piotr Suwalski, Michalina Kolodziejczak, Lech Anisimowicz, Jacek Kubica, Eliano Pio Navarese, Mariusz Kowalewski
The objective of this report was to directly compare, by means of a systematic review and meta-analysis, redo surgical aortic valve replacement (re-sAVR) with valve-in-valve transcatheter aortic valve implantation (ViV TAVI) for patients with failed degenerated aortic bioprostheses. Multiple databases were screened for all available reports comparing ViV TAVI with re-sAVR in patients with failing degenerated aortic bioprostheses. The primary outcome was all-cause mortality determined from the longest available survival data...
September 8, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029054/prostaglandin-endoperoxide-synthase-1-ptgs1-mediates-the-timing-of-parturition-in-mice-despite-unhindered-uterine-contractility
#14
Jennifer L Herington, Christine O'Brien, Michael F Robuck, Wei Lei, Naoko Brown, J Chris Slaughter, Bibhash C Paria, Anita Mahadevan-Jansen, Jeff Reese
Cyclooxygenase (COX)-derived prostaglandins stimulate uterine contractions and prepare the cervix for parturition. Prior reports suggest Cox-1 (Ptgs1) knockout (KO) mice exhibit delayed parturition due to impaired luteolysis, yet the mechanism for late-onset delivery remains unclear. Here, we examined key factors for normal onset of parturition to determine whether any could account for the delayed parturition phenotype. Pregnant Cox-1KO mice did not display altered timing of embryo implantation or post-implantation growth...
September 29, 2017: Endocrinology
https://www.readbyqxmd.com/read/29028694/individualized-biventricular-epicardial-augmentation-technology-in-a-drug-induced-porcine-failing-heart-model
#15
Lasse Jagschies, Marc Hirschvogel, Jose Matallo, Andreas Maier, Karin Mild, Horst Brunner, Rabea Hinkel, Michael W Gee, Peter Radermacher, Stephen M Wildhirt, Sebastian Hafner
For treatment of advanced heart failure, current strategies include cardiac transplantation or blood-contacting pump technology associated with complications, including stroke and bleeding. This study investigated an individualized biventricular epicardial augmentation technology in a drug-induced porcine failing heart model. A total of 11 pigs were used, for the assessment of hemodynamics and cardiac function under various conditions of support pressures and support durations (n = 4), to assess device positioning and function by in vivo computer tomographic imaging (n = 3) and to investigate a minimally invasive implantation on the beating heart (n = 4)...
October 12, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29026048/spinal-cord-stimulation-for-chronic-non-cancer-pain-a-review-of-current-evidence-and-practice
#16
S Sc Wong, C W Chan, C W Cheung
Spinal cord stimulation provides analgesia through electrical stimulation of the dorsal column of the spinal cord via electrode leads placed into the epidural space. In traditional tonic stimulation, a painful sensation is replaced with paraesthesia. Spinal cord stimulation is effective in reducing neuropathic pain, enhancing function, and improving quality of life in different chronic pain conditions. Currently, there is most evidence to support its use for failed back surgery syndrome when multidisciplinary conventional management is unsuccessful...
October 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29023617/socket-shield-technique-for-implant-placement-in-the-esthetic-zone-a-case-report
#17
Matthias Petsch, Benedikt Spies, Ralf-Joachim Kohal
Improvements in implant design, placement protocols, and sequences for reconstruction in the anterior region have enabled clinicians to provide their patients with esthetically acceptable results. Yet from a clinical standpoint, the predictable preservation of the peri-implant soft tissue remains challenging and tissue grafting is often necessary to compensate for ridge contour changes in postextraction sites. In animal and clinical studies, the socket shield technique has shown its potential to prevent resorption of buccal tissues...
November 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29023305/insights-into-the-therapeutic-effect-of-responsive-neurostimulation-assessed-with-scalp-eeg-recording-a-case-report
#18
Maria Jose Bruzzone, Naoum Issa, Sandra Rose, Peter Warnke, Vernon L Towle, James X Tao, Shasha Wu
The responsive neurostimulation system (RNS) is the first closed-loop neurostimulator approved as an adjunctive treatment for adults with medically refractory focal epilepsy from no more than two seizure foci. In addition to its therapeutic effect, it provides chronic intracranial EEG recordings, with limited storage capacity. Long-term monitoring with scalp EEG recordings can provide additional information regarding seizure patterns, the efficacy of RNS stimulation in aborting individual seizures, and the net effect of RNS on seizure control...
October 10, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29020413/incidence-predictors-and-clinical-outcomes-of-coronary-obstruction-following-transcatheter-aortic-valve-replacement-for-degenerative-bioprosthetic-surgical-valves-insights-from-the-vivid-registry
#19
Henrique B Ribeiro, Josep Rodés-Cabau, Philipp Blanke, Jonathon Leipsic, Jong Kwan Park, Vinayak Bapat, Raj Makkar, Matheus Simonato, Marco Barbanti, Joachim Schofer, Sabine Bleiziffer, Azeem Latib, David Hildick-Smith, Patrizia Presbitero, Stephan Windecker, Massimo Napodano, Alfredo G Cerillo, Mohamed Abdel-Wahab, Didier Tchetche, Claudia Fiorina, Jan-Malte Sinning, Mauricio G Cohen, Mayra E Guerrero, Brian Whisenant, Fabian Nietlispach, José Honório Palma, Luis Nombela-Franco, Arend de Weger, Malek Kass, Fabio Sandoli de Brito, Pedro A Lemos, Ran Kornowski, John Webb, Danny Dvir
Aims: There are limited data on coronary obstruction following transcatheter valve-in-valve (ViV) implantation inside failed aortic bioprostheses. The objectives of this study were to determine the incidence, predictors, and clinical outcomes of coronary obstruction in transcatheter ViV procedures. Methods and results: A total of 1612 aortic procedures from the Valve-in-Valve International Data (VIVID) Registry were evaluated. Data were subject to centralized blinded corelab computed tomography (CT) analysis in a subset of patients...
August 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29019882/koebner-phenomenon-induced-by-failed-revisional-orthopedic-surgery-but-remitted-with-bone-union-a-case-report
#20
Yiing-Feng Hwang, Nai-Yuan Wu, Pei-Yuan Lee
RATIONALE: Trauma or surgical incision might cause Koebner phenomenon (KP) in patients with cutaneous diseases, but seldom studies reported KP induced by repeated orthopedic surgery. PATIENT CONCERNS: The 22-year-old man did not have any prior histories of cutaneous diseases. Two months after the revision surgery for nonunion of the left femoral shaft fracture, KP was noted by psoriasis presented at the surgical scar, left thigh, scalp, and trunk. Phototherapy and topical treatments were prescribed but the effect was limited...
October 2017: Medicine (Baltimore)
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