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Shafay Raheel, Izzat Shbeeb, Cynthia S Crowson, Eric L Matteson
OBJECTIVE: To determine time trends in the incidence and survival of polymyalgia rheumatica (PMR) over a 15 year period in Olmsted County, Minnesota, USA and to examine trends in incidence of PMR in the population by comparing this time period to a previous incidence cohort from the same population base. METHODS: All cases of incident PMR among Olmsted County, Minnesota residents in 2000-2014 were identified to extend the previous 1970-1999 cohort. Detailed review of all individual medical records was performed...
October 21, 2016: Arthritis Care & Research
Kurt K Hubbard, Diane Blyler
Research involving working memory has indicated that stress and anxiety compete for attentional resources when a person engages in attention-dependent cognitive processing. The purpose of this study was to investigate the impact of perceived stress and state anxiety on working memory and academic performance among health science students and to explore whether the reduction of stress and anxiety was achieved through progressive muscle relaxation (PMR) training. A convenience sample of 128 graduate students participated in this study...
November 2016: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
Eugen Widmeier, Weizhen Tan, Merlin Airik, Friedhelm Hildebrandt
INTRODUCTION: Steroid-resistant nephrotic syndrome (SRNS) inevitably progresses to end-stage kidney disease, requiring dialysis or transplantation for survival. However, treatment modalities and drug discovery remain limited. Mutations in over 30 genes have been discovered as monogenic causes of SRNS. Most of these genes are predominantly expressed in the glomerular epithelial cell, the podocyte, placing it at the center of the pathogenesis of SRNS. Podocyte migration rate (PMR) represents a relevant intermediate phenotype of disease in monogenic causes of SRNS...
October 19, 2016: American Journal of Physiology. Renal Physiology
J Gonzalo N Irisarri, Justin D Derner, Lauren M Porensky, David J Augustine, Justin L Reeves, Kevin E Mueller
Grazing intensity elicits changes in the composition of plant functional groups in both shortgrass steppe (SGS) and northern mixed-grass prairie (NMP) in North America. How these grazing intensity-induced changes control aboveground net primary production (ANPP) responses to precipitation remains a central open question, especially in light of predicted climate changes. Here, we evaluated effects of four levels (none, light, moderate, and heavy) of long-term (>30 yr) grazing intensity in SGS and NMP on: (1) ANPP; (2) precipitation-use efficiency (PUE, ANPP : precipitation); and (3) precipitation marginal response (PMR; slope of a linear regression model between ANPP and precipitation)...
July 2016: Ecological Applications: a Publication of the Ecological Society of America
Bruno Luciano Carneiro Alves de Oliveira, Ronir Raggio Luiz
OBJECTIVE: The skin color/race and urbanity are structural determinants of health. The relationship between these variables produces structure of social stratification that defines inequalities in the experiences of life and death. Thus, this study describes the characteristics of the mortality indicators by skin color/race according level of urbanity and aggregation to the metropolitan region (MR) of 5565 cities in Brazil, controlling for gender and age. DESIGN: Descriptive study which included the calculation of measures relating to 1,050,546 deaths in the year survey of 2010 by skin color/race White, Black, and Brown according to both sexes, for five age groups and three levels of urbanity of cities in Brazil that were aggregated or not to the MR in the year of study...
October 17, 2016: Ethnicity & Health
Giovanna Restuccia, Luigi Boiardi, Alberto Cavazza, Mariagrazia Catanoso, Pierluigi Macchioni, Francesco Muratore, Alessandra Soriano, Luca Cimino, Raffaella Aldigeri, Filippo Crescentini, Nicolò Pipitone, Carlo Salvarani
OBJECTIVE: To evaluate the frequency of long-term remission after glucocorticoids (GCs) suspension in an Italian cohort of patients with biopsy-proven GCA and to identify factors that may predict long-term remission. METHODS: We evaluated 131 patients with biopsy-proven transmural GCA diagnosed and followed up at the Rheumatology Unit of Reggio Emilia Hospital (Italy) for whom sufficient information was available from the time of diagnosis until at least 18 months of follow-up...
October 11, 2016: Journal of Autoimmunity
Andrew Scarsbrook, Sriram Vaidyanathan, Fahmid Chowdhury, Sarah Swift, Rachel Cooper, Chirag Patel
OBJECTIVES: To evaluate the utility of a standardized qualitative scoring system for treatment response assessment at 18F-FDG PET-CT in patients undergoing chemoradiotherapy for locally advanced cervical carcinoma and correlate this with subsequent patient outcome. METHODS: Ninety-six consecutive patients with locally advanced cervical carcinoma treated with radical chemoradiotherapy (CRT) in a single centre between 2011 and 2014 underwent 18F-FDG PET-CT approximately 3 months post-treatment...
October 14, 2016: European Journal of Nuclear Medicine and Molecular Imaging
Berivan Bitik, Rıdvan Mercan, Abdurrahman Tufan, Engin Tezcan, Hamit Küçük, Mustafa İlhan, Mehmet Akif Öztürk, Seminur Haznedaroğlu, Berna Göker
OBJECTIVE: In the case of high erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels, the diagnosis of the underlying disease can be challenging especially in serologically unrevealing patients who have nonspecific clinical findings. We aimed to investigate the final distribution of definitive diagnoses in patients who initially presented with nonspecific clinical findings and sustained elevations in serum ESR/CRP levels. MATERIAL AND METHODS: The medical records of patients hospitalized in a rheumatology clinic between January 2010 and January 2011 were retrospectively analyzed...
December 2015: Eur J Rheumatol
Otilia V Vieira
Disruption of the cell plasma membrane can occur due to mechanical damage, pore forming toxins, etc. Resealing or plasma membrane repair (PMR) is the emergency response required for cell survival. It is triggered by Ca(2+) entering through the disruption, causing organelles such as lysosomes located underneath the plasma membrane to fuse rapidly with the adjacent plasma membrane. We have recently identified some of the molecular traffic machinery that is involved in this vital process. Specifically, we showed that 2 members of the Rab family of small GTPases, Rab3a and Rab10, are essential for lysosome exocytosis and PMR in cells challenged with a bacterial toxin, streptolysin-O (SLO)...
September 29, 2016: Small GTPases
Emna Toulgui, Sonia Jemni, Samia Frioui, Nadia Lazreg, Sahbi Mtaouaa, Fayçal Khachnaoui
OBJECTIVE: Tuberculous spondylitis, or Pott's disease, is a public health problem in Tunisia, where it occurs as an endemic disease. It is the most common and most severe articular bone tuberculosis. It is responsible for a major handicap because of its location and its destructive nature. This work aims to assess the contribution of rehabilitation for patients with Pott's disease. MATERIAL/PATIENTS AND METHODS: A retrospective study that included 29 patients with Pott's disease and hospitalized in PMR Service...
September 2016: Annals of Physical and Rehabilitation Medicine
Shenhao Dai, Marie Jaeger, Pierre Simon Jouk, Dominic Pérennou, Klaus Dieterich
OBJECTIVE: Arthrogryposis multiplex congenita (AMC) is a clinical diagnosis characterized by the presence of at least two joint contractures at birth. Causes of AMC are numerous involving CNS, neuromuscular system, connective and bone tissue. This study is the first to describe disability patterns of a cohort of adults with AMC. MATERIALS/PATIENTS AND METHODS: Thirty-nine patients (age 33.8±11.5 years; 23 females) underwent between 2010 and 2016 a 4 day evaluation in the PMR ward during the multidisciplinary consultations for AMC at the Reference Centre of Congenital Anomalies in Grenoble: 25 with amyoplasia, 8 with distal arthrogryposis (DA), and 6 with other atypical diseases...
September 2016: Annals of Physical and Rehabilitation Medicine
Sana Salah, Mariem Rekik, Soumaya Boudokhane, Houda Migaou, Anis Jellad, Zohra Ben Salah Frih
OBJECTIVE: To assess the prevalence of sleep disorders (SD) in ischemic stroke (IS) patients followed in physical medicine and rehabilitation (PMR) and to compare this prevalence to that found in a control population. MATERIAL/PATIENTS AND METHODS: A cross-sectional study was conducted over a period of 8 months. We enrolled IS patients and case controls matched for age and sex and who met the inclusion criteria. The data studied were epidemiological and clinical...
September 2016: Annals of Physical and Rehabilitation Medicine
Marie Orentin, Victorine Quintaine, Alain Yelnik, Marylène Jousse, Leila Tlili, Anna Bernard, Maryse Guillemette
OBJECTIVE: Music therapy enhances awareness of sound perception and musical sensorial experience often highly impaired following a stroke, confirmed by music's neurosciences. The study aims to verify its reception and utility in a Physical Medicine and Rehabilitation (PMR) service with professional team and patients. MATERIAL/PATIENTS AND METHODS: Eleven hospitalized patients were included after stoke (without regular instrumental practice, speech disorder, severe hearing loss nor psychiatric history)...
September 2016: Annals of Physical and Rehabilitation Medicine
Jean-Pascal Devailly, Laurence Josse
OBJECTIVE: Care programs in MPR formalize, for homogeneous profile of patients the steps of a multidisciplinary approach based on the rehabilitation potential and focused on improving functional status. The aim is to build a custom clinical pathway for patients with stroke followed in Physical Medicine and Rehabilitation Day Hospital by connecting each step systematically formalized a traceability tool in the information system in view a fair payment of a care program. MATERIAL/PATIENTS AND METHODS: Our outpatient hospital PMR team has built a clinical pathway according the method of the High Authority of Health, supported by MPR criteria defined by FEDMER and texts regulating the activity of French post-acute care (SSR)...
September 2016: Annals of Physical and Rehabilitation Medicine
Benjamin Bertheas, Candice Bertheas, André Thévenon
OBJECTIVE: The general practitioner (GP) has a major role in the direction of chronic low back pain (LBCP). The purpose of the study is to determine the criteria that lead the Nord Pas de Calais GP guide the CLBP patient to the Physical Medicine and Rehabilitation of the Lille University Hospital. MATERIALS/PATIENTS AND METHODS: This is a descriptive study by questionnaire sent to 300 North G. Calais drawn. The criteria were analyzed uni- and bi-varied and CART(®) algorithm was developed from R(®) software...
September 2016: Annals of Physical and Rehabilitation Medicine
Johann Beaudreuil, Jean Marie Coudreuse, Christelle N Guyen, Philippe Deat, Aurore Chabaud, Bruno Pereira, Alain Lorenzo, Frédéric Sailhan, François Rannou, Emmanuel Coudeyre
OBJECTIVE: To develop an algorithm to help orthosis prescription for knee osteoarthritis patients. MATERIAL/PATIENTS AND METHODS: Systematic review of the literature using a qualitative analysis on Pubmed databases, Cochrane Library and Pedro from 1966 to 2015, using the keywords "knee osteoarthritis", "orthosis" with recommendations and highest quality trials. Development of a preliminary version of the algorithm using data from the literature and taking into account experience of different health professionals involved in the management of osteoarthritis patients...
September 2016: Annals of Physical and Rehabilitation Medicine
Amélie Bremare, Nicolas Girardon, Mélanie Margot
Within the framework of cooperation between the physical medicine and rehabilitation (PMR) department and psychiatry department in our establishment with care and education, we have created in 2006 a unit with both somatic and psychic care, allowing management of preadolescents and adolescents suffering from complex somatoform disorder with pain in full-time hospitalization. They have chronic pain associated with motor exclusion of a limb, which have for consequence a participation restriction on scholar and extra-scholar activities with a larger impact than it should be...
September 2016: Annals of Physical and Rehabilitation Medicine
Samira Lahrabli, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Spasticity of the upper limb is a disabling symptom in patients with vascular hemiplegia, both functionally and orthopedic evolution of these patients. Many treatments exist for spasticity, and botulinum toxin may be an attractive therapeutic alternative, to fight against the often deleterious spasticity. MATERIAL/PATIENTS AND METHODS: We report a retrospective work of 10 spastic patients treated with ultrasound-guided injection of botulinum toxin into the MPR Casablanca service...
September 2016: Annals of Physical and Rehabilitation Medicine
Soumaya Boudokhane, Amine Kalai, Aymen Haj Salah, Houda Migaou, Sana Salah, Anis Jellad, Mourad Gahbiche, Zohra Ben Salah Frih
OBJECTIVE: The aim of our study was to determine the demographic characteristics and the pathway of severe traumatic brain injury (STBI) victims in the Tunisian population. MATERIAL/PATIENTS AND METHODS: Our study included 26 patients victims of STBI hospitalized in intensive care unit, among 450 traumatic head injuries admitted to the Teaching Hospital of Fattouma Bourguiba in Monastir during the year 2014. The studied parameters were: demographic characteristics of the population, circumstances of the accident, transport modalities to the hospital, assessments of the injury types, duration of coma, length of hospitalization in the Intensive Care Unit (ICU) and finally the discharge mode after the ICU stay (transfer to neurosurgery ward, to rehabilitation unit, or home discharged)...
September 2016: Annals of Physical and Rehabilitation Medicine
Sameh Ghroubi, Samar Alila, Islem Feki, Mohamed Habib Elleuch
OBJECTIVE: The aim of this study was to assess the quality of life (QoL) of traumatic brain injury (TBI) patients and to explore its predictive factors. MATERIAL/PATIENTS AND METHODS: This is a descriptive and analytical cross-sectional study, including 27 TBI patients followed in the physical medicine and rehabilitation department (PMR). The collected data were: age, educational level, marital status, initial Glosgow score and intensive care unit length of stay...
September 2016: Annals of Physical and Rehabilitation Medicine
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