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https://www.readbyqxmd.com/read/29676871/-management-of-renal-cell-carcinoma-associated-with-an-extensive-inferior-vena-cava-tumor-thrombus
#1
C Battisti, F Sohngen, J P Lavigne, R Andrianne
Each main kind of cancer has rather typical or atypical clinical presentations, depending upon several factors related to histopathology or staging. The diagnosis of renal cell carcinoma associated with an extensive inferior vena cava tumor thrombus usually implies prognostic, workup, and surgical management issues. The incidental discovery of this rare clinical entity presented as deep vein thrombosis is narrated, with some therapeutic elements, including an example of alternative surgical treatment. The importance of preoperative assessment - particularly local regarding operability, is emphasized as well...
April 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29662744/postoperative-complications-associated-with-rhbmp2-use-in-posterior-posterolateral-lumbar-fusion
#2
Nabil Esmail, Zorica Buser, Jeremiah R Cohen, Darrel S Brodke, Hans-Joerg Meisel, Jong-Beom Park, Jim A Youssef, Jeffrey C Wang, S Tim Yoon
Study Design: Retrospective database review. Objective: Posterior/posterolateral lumbar fusion (PLF) is an effective treatment for a variety of spinal disorders; however, variations in surgical technique have different complication profiles. The aim of our study was to quantify the frequency of various complications in patients undergoing PLF with and without human recombinant bone morphogenetic protein 2 (rhBMP2). Methods: We queried the orthopedic subset of the Medicare database (PearlDiver) between 2005 and 2011 for patients undergoing PLF procedures with and without rhBMP2...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29661440/renopancreatic-transplantation-evaluation-of-15-years-in-131-patients
#3
C G Marmanillo, C Langaro, J E Nicoluzzi, R T Belila, M Macri, R Zamprogna, M Luvizotto, M Takahashi
BACKGROUND: The most common multiple-organ transplant is the simultaneous pancreas-kidney transplantation (SPK). It is usually offered to patients who have insulin-dependent diabetes mellitus and those with diabetic nephropathy and renal failure that has already been established. In this study we present the results of 15 years of SPK in a transplant hospital center in Paraná, Brazil, and evaluated survival, immunosuppression, and transplant-related problems. METHODS: This study was a retrospective analysis of 131 SPK transplants performed at the Angelina Caron Hospital between January 2001 and December 2015...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661433/better-selection-criteria-with-prognostic-factors-for-liver-transplantation
#4
L S Nacif, R S Pinheiro, V Rocha-Santos, V M Barbosa, A P de Moura Dias, R B Martino, R A Macedo, L Ducatti, L Haddad, F Galvão, W Andraus, L Carneiro D' Albuquerque
BACKGROUND: Liver transplantation has evolved significantly in recent years, with each advancement part of the effort toward increasing patient and graft survival as well as quality of life. The objective of this study was to evaluate the prognostic factors and selection criteria for liver transplantation. METHODS: Our study was a statistical analysis, logistic regression, and survival evaluation of a total of 80 liver transplants that were performed between June 1, 2016 and September 24, 2016...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661346/drug-eluting-stents-versus-bare-metal-stents-in-patients-with-end-stage-renal-disease
#5
Yushu Wang, Sui Zhu, Peijuan Gao, Yucheng Chen, Qing Zhang
BACKGROUND: The clinical outcomes of drug-eluting stents versus bare-metal stents in end-stage renal disease patients remains controversial. METHODS: A comprehensive literature search of Pubmed, Embase and Cochrane Library from January 2000 until November 2016 was conducted to identify relevant articles. We pooled the odds ratios (OR) from individual studies and conducted heterogeneity, quality assessment and publication bias analyses. RESULTS: A total of 18 studies with 44,194 patients were identified...
April 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29659362/-recurrent-atypical-hemolytic-uremic-syndrome-after-renal-transplantation-treatment-with-eculizumab
#6
Ana B Latzke, Pehuén Fernández, Carlos Chiurchiu, Daniela Sarmantano, Javier De Arteaga, Walter Douthat, Jorge De la Fuente
Atypical hemolytic uremic syndrome (aHUS) is a rare entity. It is characterized by a thrombotic microangiopathy (nonimmune hemolytic anemia, thrombocytopenia, and acute renal failure), with a typical histopathology of thickening of capillary and arteriolar walls and an obstructive thrombosis of the vascular lumen. The syndrome is produced by a genetic or acquired deregulation of the alternative pathway of the complement system, with high rates of end stage renal disease, post-transplant recurrence, and high mortality...
2018: Medicina
https://www.readbyqxmd.com/read/29657196/atypical-hemolytic-uremic-syndrome-a-monocentric-adult-tunisian-study-and-review-of-literature
#7
R Kherder-Elfekih, M Hajji, L Ben Fatma, H Jebali, I Mami, W Smaoui, M Krid, L Rais, S Beji, K Zouaghi, M Sellami-Kallel
Atypical hemolytic uremic syndrome (aHUS) is characterized by microvascular thrombosis resulting in thrombocytopenia, hemolytic anemia, and multiorgan dysfunction. It is associated with genetic or acquired disorders of regulatory components of the complement system. For our study, we collected data from 16 patients diagnosed with aHUS between January 2010 and January 2014. The mean age was 33.6 years. The female-to-male ratio was 3. The median follow-up duration was 27 ± 3.5 months. The most common clinical presentation was hypertension...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29655462/obesity-thrombotic-risk-and-inflammation-in-cancer
#8
Benjamín Rubio-Jurado, Luz-Ma-Adriana Balderas-Peña, Eduardo E García-Luna, María G Zavala-Cerna, Carlos Riebeling-Navarro, Pedro A Reyes, Arnulfo H Nava-Zavala
Neoplasms exhibits a high incidence and mortality rates due to their complex and commonly overlapping clinical, biochemical, and morphologic profiles influenced by acquired or inherited molecular abnormalities, cell of origin, and level of differentiation. Obesity appears related to ~20% of cancers including endometrial, esophageal, colorectal, postmenopausal breast, prostate, and renal. Several factors other than obesity, i.e., insulin, insulin-like growth factor, sexual hormones, and adipokines may play a potential role in neoplasia...
2018: Advances in Clinical Chemistry
https://www.readbyqxmd.com/read/29645355/the-european-experience-on-robot-assisted-kidney-transplantation-minimum-of-one-year-follow-up
#9
Angelo Territo, Lluis Gausa, Antonio Alcaraz, Mireia Musquera, Nicolas Doumerc, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Selcuk Sahin, Volkan Tuǧcu, Giuseppe Basile, Alberto Breda
OBJECTIVES: To evaluate functional results, graft survival, and late complications in patients who underwent robot-assisted kidney transplantation (RAKT), with a minimum follow-up of one year. In addition: to analyze the correlation between surgical data and functional results at a minimum 1-year follow-up and the correlation between renal function in the immediate postoperative period and after one year. MATERIALS AND METHODS: A common prospective recruitment database of RAKT was created by the European Robotic Urological Section (ERUS) RAKT working group, including eight different European centers...
April 12, 2018: BJU International
https://www.readbyqxmd.com/read/29644836/elevated-extracellular-nucleosomes-and-their-relevance-to-inflammation-in-stage-5-chronic-kidney-disease
#10
Trung Phan, Ryan McMillan, Leonidas Skiadopoulos, Amanda Walborn, Debra Hoppensteadt, Jawed Fareed, Vinod Bansal
BACKGROUND: Chronic kidney disease is a disorder characterized by a pro-inflammatory state that is associated with increased morbidity and mortality. Endogenous damage- associated molecular patterns, including nucleosomes, may contribute to this persistent inflammation. The aim of this study was to profile and evaluate the clinical significance of circulating nucleosomes in patients with Stage 5 chronic kidney disease (CKD5) on hemodialysis (HD). METHODS: Under institutional review board approval, plasma samples were collected from 90 CKD5-HD patients (45 male and 45 female) prior to hemodialysis...
April 11, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29628300/long-term-outcomes-of-selective-renal-artery-embolization-for-renal-arteriovenous-fistulae-with-dilated-venous-sac
#11
Yasushi Kimura, Keigo Osuga, Yusuke Ono, Tetsuro Nakazawa, Hiroki Higashihara, Noriyuki Tomiyama
PURPOSE: To retrospectively evaluate the role of selective renal artery embolization for renal arteriovenous fistulae (AVFs) with dilated venous sac. MATERIALS AND METHODS: Between 2002 and 2015, 14 patients (7 men and 7 women; mean age, 60 years) with a single renal AVF with dilated venous sac underwent selective renal artery embolization. Three patients presented with gross hematuria, 4 presented with occult blood in urine, and 1 presented with chronic heart failure...
April 6, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29623408/-thromboembolism-prophylaxis-in-old-age
#12
Gabriele Röhrig, Gerald Kolb
Anticoagulation in geriatric patients is challenging regarding the risk of bleeding complications and thromboembolic problems. Age, comorbidities, such as renal insufficiency and polymedication have a vital impact on bleeding and thromboembolic risks; however, age is not an exclusion criterion for withholding anticoagulation. Age is the main risk factor for deep vein thrombosis and atrial fibrillation becomes more relevant with aging. Older patients with atrial fibrillation have a particularly high risk of having a stroke...
April 2018: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/29622761/simultaneous-pancreas-kidney-transplantation-in-a-patient-with-heparin-induced-thrombocytopenia-on-dabigatran-therapy
#13
Agnieszka Jóźwik, Wojciech Lisik, Jarosław Czerwiński, Maciej Kosieradzki
BACKGROUND New oral anticoagulants like direct thrombin inhibitors are an attractive alternative to vitamin K antagonists as anticoagulation therapy and can be used in heparin-induced thrombocytopenia. They are convenient in low-risk surgery, as there is no need for bridging with heparins. Patients who need urgent major surgery are at similar risk as on warfarin therapy, which, however, is much higher than in elective procedures. Due to their elimination profiles, these drugs are generally contraindicated in patients with severe renal insufficiency...
April 6, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29622068/-renal-venous-thrombosis-as-a-complication-of-nephrotic-syndrome
#14
Nata Kermanian, Kaj Aage Hansen
Venous thromboembolism is a very common complication of nephrotic syndrome (NS). This case report concerns a 19-year-old male, who had known NS and was admitted two times in a short period, first presenting with recurrent symptoms of NS and later with an acute abdomen, which was diagnosed as renal venous thrombosis (RVT) and pulmonary thromboembolism. The patient was treated with prednisolone and therapeutic doses of dalteparin and warfarin. Venous thrombosis, particularly RVT and pulmonary thromboembolism, should be considered in patients with NS...
April 2, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29619261/septic-pulmonary-emboli-and-renal-abscess-caused-by-staphylococcus-aureus-in-an-hiv-infected-patient
#15
Isaí Medina-Piñón, Alan Ledif Reyes-Mondragón, Michel Fernando Martínez-Reséndez, Adrián Camacho-Ortiz
Staphylococcus aureus is a common cause of bacteremia in the general population and can lead to serious metastatic infection particularly in immunocompromised persons. However, prompt diagnosis and management can result in favorable outcomes. In the following case report, the clinical course of an HIV-infected man is presented; he developed bloodstream infection (BSI) and associated complications: septic pulmonary embolism, right renal abscess, and ipsilateral renal vein thrombosis. Methicillin-resistant Staphylococcus aureus (MRSA) was identified as the cause of sepsis and successfully treated with surgery and antimicrobials...
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29618581/causes-and-predictors-of-30-day-readmission-in-patients-with-acute-myocardial-infarction-and-cardiogenic-shock
#16
Mahek Shah, Shantanu Patil, Brijesh Patel, Manyoo Agarwal, Carlos D Davila, Lohit Garg, Sahil Agrawal, Navin K Kapur, Ulrich P Jorde
BACKGROUND: Acute myocardial infarction (AMI) occurs as a result of irreversible damage to cardiac myocytes secondary to lack of blood supply. Cardiogenic shock complicating AMI has significant associated morbidity and mortality, and data on postdischarge outcomes are limited. METHODS AND RESULTS: We derived the study cohort of patients with AMI and cardiogenic shock from the 2013 to 2014 Healthcare Cost and Utilization Project National Readmission Database. Incidence, predictors, and causes of 30-day readmissions were analyzed...
April 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29618162/renal-impairment-recurrent-venous-thromboembolism-and-bleeding-in-cancer-patients-with-acute-venous-thromboembolism-analysis-of-the-catch-study
#17
Rupert Bauersachs, Agnes Y Y Lee, Pieter W Kamphuisen, Guy Meyer, Mette S Janas, Mikala F Jarner, Alok A Khorana
OBJECTIVE:  This article assesses the impact of renal impairment (RI) on the efficacy and safety of anticoagulation in patients with cancer-associated thrombosis from the Comparison of Acute Treatments in Cancer Hemostasis (CATCH) study (NCT01130025). MATERIALS AND METHODS:  Renal function was assessed using the Modification of Diet in Renal Disease equation in patients with cancer-associated thrombosis who received either tinzaparin (175 IU/kg) once daily or warfarin for 6 months, in an open-label, randomized, multi-centre trial with blinded adjudication of outcomes...
April 4, 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29607737/dual-antiplatelet-therapy-after-percutaneous-left-atrial-appendage-occlusion-single-center-experience-with-the-amplatzer-cardiac-plug
#18
Philippe B Bertrand, Melanie Habran, Karlijn Kenis, Julie Lecomte, Linde Moonen, Didier Stroobants, Edouard Benit
BACKGROUND: Percutaneous left atrial appendage occlusion (LAAO) is an alternative to anticoagulation in atrial fibrillation patients at high bleeding risk. Dual antiplatelet therapy (DAPT) is generally recommended in the months following the procedure to prevent thrombotic complications. The aim of this study was to evaluate the safety and efficacy of DAPT after LAAO in a single-centre population of high bleeding risk patients. METHODS: All patients who received DAPT after LAAO using the Amplatzer Cardiac Plug at Jessa Hospital (Hasselt, BE) between February 2011 and October 2016 were included...
April 1, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29607314/glucagon-like-peptide-1-mediates-the-protective-effect-of-the-dipeptidyl-peptidase-iv-inhibitor-on-renal-fibrosis-via-reducing-the-phenotypic-conversion-of-renal-microvascular-cells-in-monocrotaline-treated-rats
#19
Jian Xu, Jingjing Wang, Yusheng Cheng, Xiang Li, Mengyu He, Jiali Zhu, Honghao Han, Guihong Wei, Hui Kong, Weiping Xie, Hong Wang, Xiangrong Zuo
Chronic kidney diseases are characterized by renal fibrosis with excessive matrix deposition, leading to a progressive loss of functional renal parenchyma and, eventually, renal failure. Renal microcirculation lesions, including the phenotypic conversion of vascular cells, contribute to renal fibrosis. Here, renal microcirculation lesions were established with monocrotaline (MCT, 60 mg/kg). Sitagliptin (40 mg/kg/d), a classical dipeptidyl peptidase-4 (DPP-4) inhibitor, attenuated the renal microcirculation lesions by inhibiting glomerular tuft hypertrophy, glomerular mesangial expansion, and microvascular thrombosis...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29606262/-identifying-the-specific-causes-of-kidney-allograft-loss-a-population-based-study
#20
Charlotte Lohéac, Olivier Aubert, Alexandre Loupy, Christophe Legendre
INTRODUCTION: Results of kidney transplantation have been improving but long-term allograft survival remains disappointing. The objective of the present study was to identify the specific causes of renal allograft loss, to assess their incidence and long-term outcomes. METHODS: A total of 4783 patients from four French centres, transplanted between January 2004 and January 2014 were prospectively included. A total of 9959 kidney biopsies (protocol and for cause) performed between January 2004 and March 2015 were included...
April 2018: Néphrologie & Thérapeutique
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