keyword
MENU ▼
Read by QxMD icon Read
search

Gamma knife radiation

keyword
https://www.readbyqxmd.com/read/28725514/gamma-knife-stereotactic-radiosurgery-for-grade-2-meningiomas
#1
Tamer Refaat, Michelle Gentile, Sean Sachdev, Prarthana Dalal, Anish Butala, Stanley Gutiontov, Irene Helenowksi, Plato Lee, Vythialinga Sathiaseelan, Orin Bloch, James Chandler, John A Kalapurakal
Purpose  This study aims to report long-term clinical outcomes after Gamma Knife radiosurgery (GKRS) for intracranial grade 2 meningiomas. Methods  In this Institutional Review Board approved study, we reviewed records of all patients with grade 2 meningiomas treated with GKRS between 1998 and 2014. Results  A total of 97 postoperative histopathologically confirmed grade 2 meningiomas in 75 patients were treated and are included in this study. After a mean follow-up of 41 months, 28 meningiomas had local recurrence (29...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28690660/a-case-of-breast-cancer-brain-metastasis-with-a-16-year-time-interval-without-evidence-of-cancer-recurrence
#2
Shoko Merrit Yamada, Yusuke Tomita, Soichiro Shibui, Takashi Kurokawa, Yasuhisa Baba
The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemotherapy for uterine and breast cancer 24 years prior and 16 years prior, respectively. Although she had not received any anticancer treatment for 10 years, no recurrences were identified using whole body scans...
June 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28681759/dose-fractionated-gamma-knife-radiosurgery-for-large-arteriovenous-malformations-on-daily-or-alternate-day-schedule-outside-the-linear-quadratic-model-proof-of-concept-and-early-results-a-substitute-to-volume-fractionation
#3
Kanchan Kumar Mukherjee, Narendra Kumar, Manjul Tripathi, Arun S Oinam, Chirag K Ahuja, Sivashanmugam Dhandapani, Rakesh Kapoor, Sushmita Ghoshal, Rupinder Kaur, Sandeep Bhatt
BACKGROUND: To evaluate the feasibility, safety and efficacy of dose fractionated gamma knife radiosurgery (DFGKRS) on a daily schedule beyond the linear quadratic (LQ) model, for large volume arteriovenous malformations (AVMs). MATERIAL AND METHODS: Between 2012-16, 14 patients of large AVMs (median volume 26.5 cc) unsuitable for surgery or embolization were treated in 2-3 of DFGKRS sessions. The Leksell G frame was kept in situ during the whole procedure. 86% (n = 12) patients had radiologic evidence of bleed, and 43% (n = 6) had presented with a history of seizures...
July 2017: Neurology India
https://www.readbyqxmd.com/read/28665251/stereotactic-radiosurgery-for-medically-refractory-multiple-sclerosis-related-tremor
#4
Sudesh S Raju, Ajay Niranjan, Edward A Monaco, John C Flickinger, L Dade Lunsford
OBJECTIVE Multiple sclerosis (MS) is a neurodegenerative disease that can lead to severe intention tremor in some patients. In several case reports, conventional radiotherapy has been reported to possibly exacerbate MS. Radiosurgery dramatically limits normal tissue irradiation to potentially avoid such a problem. Gamma Knife thalamotomy (GKT) has been established as a minimally invasive technique that is effective in treating essential tremor and Parkinson's disease-related tremor. The goal in this study was to analyze the outcomes of GKT in patients suffering from medically refractory MS-related tremor...
June 30, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28660317/ischemic-stroke-after-radiation-therapy-for-pituitary-adenomas-a-systematic-review
#5
REVIEW
A van Westrhenen, I S Muskens, J J C Verhoeff, T R S Smith, M L D Broekman
Radiation therapy is widely used for the treatment of residual and recurrent pituitary adenomas and proved to effectively control tumor growth. However, it is suggested that this treatment might result in an increased risk of ischemic stroke. This review aims to evaluate the radiotherapy-related risk of stroke in pituitary adenoma patients. PubMed and Embase databases were systematically searched for current literature on ischemic stroke risk after radiotherapy in pituitary adenoma, in accordance with the PRISMA statement...
June 28, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28645182/stereotactic-radiosurgery-for-brainstem-arteriovenous-malformations-a-multicenter-study
#6
Or Cohen-Inbar, Robert M Starke, Cheng-Chia Lee, Hideyuki Kano, Paul Huang, Douglas Kondziolka, Inga S Grills, Danilo Silva, Mohmoud Abbassy, Symeon Missios, Gene H Barnett, L Dade Lunsford, Jason P Sheehan
BACKGROUND: The management of brainstem arteriovenous malformations (bAVMs) is a formidable challenge. bAVMs harbor higher morbidity and mortality compared to other locations. OBJECTIVE: To review the outcomes following stereotactic radiosurgery (SRS) of bAVMs in a multicenter study. METHODS: Six medical centers contributed data from 205 patients through the International Gamma Knife Research Foundation. Median age was 32 yr (6-81). Median nidus volume was 1...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28619837/differentiation-between-treatment-induced-necrosis-and-recurrent-tumors-in-patients-with-metastatic-brain-tumors-comparison-among-11-c-methionine-pet-fdg-pet-mr-permeability-imaging-and-mri-adc-preliminary-results
#7
N Tomura, M Kokubun, T Saginoya, Y Mizuno, Y Kikuchi
BACKGROUND AND PURPOSE: In patients with metastatic brain tumors after gamma knife radiosurgery, the superiority of PET using (11)C-methionine for differentiating radiation necrosis and recurrent tumors has been accepted. To evaluate the feasibility of MR permea- bility imaging, it was compared with PET using (11)C-methionine, FDG-PET, and DWI for differentiating radiation necrosis from recurrent tumors. MATERIALS AND METHODS: The study analyzed 18 lesions from 15 patients with metastatic brain tumors who underwent gamma knife radiosurgery...
June 15, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28607829/adaptive-hypofractionated-gamma-knife-radiosurgery-in-the-acute-management-of-large-thymic-carcinoma-brain-metastases
#8
Georges Sinclair, Heather Martin, Michael Fagerlund, Amir Samadi, Hamza Benmakhlouf, Ernest Doodo
BACKGROUND: Brain metastases often lead to serious neurological impairment and life threatening states. Their acute management remains complex, particularly in the case of rare malignancies with aggressive evolution. In large single lesions, open surgery followed by radiation to the surgical cavity is widely regarded as the best approach; yet in many cases, microsurgery is not feasible due to the lesion's critical location and/or the number of brain metastases present. We report the effects of adaptive hypofractionated gamma knife radiosurgery in the acute management of critically located thymic carcinoma metastases...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28588789/curative-effect-of-stereotactic-body-radiotherapy-for-unresectable-massive-primary-liver-cancer
#9
Ya-Zheng Dang, Xin Li, Shi-Gao Huang, Wan-Ling Lu, Guodong Wang, Dongxian Zhang, Qian-Yun Wang
The aim of this study was to evaluate the curative effect of gamma knife stereotactic body radiotherapy (SBRT) for unresectable massive primary liver cancer. A total of 69 patients with unresectable massive (>10 cm) primary liver cancer who were treated by SBRT at the Department of Radiation Oncology of the 323 Hospital of People's Liberation Army (Xi'an, China) between October, 2006 and October, 2010, were analyzed. According to the Union for International Cancer Control TNM staging guidelines, the patients were graded as stage T1 (n=8), T2 (n=12), T3 (n=21) and T4 (n=28)...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28560050/gamma-knife-radiosurgery-for-the-treatment-of-uveal-melanoma-and-uveal-metastases
#10
Margaret M Reynolds, Andrea L Arnett, Ian F Parney, Ravi Kumar, Nadia N Laack, Patrick R Maloney, Timothy F Kozelsky, Yolanda I Garces, Robert L Foote, Jose S Pulido
BACKGROUND: This study retrospectively analyzed outcomes for patients undergoing gamma knife radiosurgery (GKR) for uveal melanoma (UM) and intraocular metastases. METHODS: Patients who underwent GKR for UM or intraocular metastases between 1/1/1990 and 6/1/2015 at Mayo Clinic, Rochester, MN, USA, were retrospectively analyzed. RESULTS: Eleven patients (11 eyes) had UM while seven patients (7 eyes) had intraocular metastases. Patients with UM were followed for a median of 19...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28553615/a-single-institution-analysis-of-126-patients-treated-with-stereotactic-radiosurgery-for-brain-metastases
#11
Kevin B Harris, Melanie R Corbett, Henry Mascarenhas, Kenneth Stuart Lee, Hyder Arastu, Clinton Leinweber, Andrew W Ju
BACKGROUND: The objective of this study was to report our institutional experience with Gamma Knife(®) Radiosurgery (GKRS) in the treatment of patients with brain metastases. METHODS: Retrospectively collected demographic and clinical data on 126 patients with intracranial metastases were reviewed. The patients in our study underwent GKRS at Vidant Medical Center between 2009 and 2014. Kaplan-Meier curves were used to compare survival based on clinical characteristics for univariate analysis, and a Cox proportional hazards model was used for multivariate analysis...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28537768/hypopituitarism-after-gamma-knife-radiosurgery-for-pituitary-adenoma
#12
Karin Zibar Tomšić, Tina Dušek, Ivana Kraljević, Zdravko Heinrich, Mirsala Solak, Ana Vučinović, David Ozretić, Sergej Mihailović Marasanov, Hrvoje Hršak, Darko Kaštelan
PURPOSE: The aim of the study was to investigate the incidence of and risk factors for hypopituitarism after gamma knife radiosurgery (GKRS) for pituitary adenoma. MATERIALS AND METHODS: We conducted a retrospective analysis of the pituitary function of 90 patients who underwent GKRS for pituitary adenoma at the University Hospital Centre Zagreb between 2003 and 2014. Twenty seven of them met the inclusion criteria and the others were excluded from the study due to pituitary insufficiency which was present before GKRS...
May 24, 2017: Endocrine Research
https://www.readbyqxmd.com/read/28536967/optimization-of-diagnostic-performance-for-differentiation-of-recurrence-from-radiation-necrosis-in-patients-with-metastatic-brain-tumors-using-tumor-volume-corrected-11-c-methionine-uptake
#13
Tae-Young Jung, In-Young Kim, Sa-Hoe Lim, Ki Seong Park, Dong-Yeon Kim, Shin Jung, Kyung-Sub Moon, Woo-Youl Jang, Sae-Ryung Kang, Sang-Geon Cho, Jung-Joon Min, Hee-Seung Bom, Seong Young Kwon
BACKGROUND: Tumor to normal tissue ratio (T/N ratio) on (11)C-methionine ((11)C-MET) positron emission tomography/computed tomography (PET/CT) is affected by variable factors. We investigated whether T/N ratio cutoff values corrected according to metabolic tumor volume (MTV) could improve the diagnostic performance of (11)C-MET PET/CT for diagnosis of recurrence in patients with metastatic brain tumor. Forty-eight patients with metastatic brain tumors underwent (11)C-MET PET/CT for differential diagnosis between recurrence and radiation necrosis after gamma knife radiosurgery (GKR)...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28527605/analysis-of-gafchromic-ebt3-film-calibration-irradiated-with-gamma-rays-from-different-systems-gamma-knife-and-cobalt-60-unit
#14
Monsen Najafi, Ghazale Geraily, Alireza Shirazi, Mahbod Esfahani, Javad Teimouri
In recent years, Gafchromic films are used as an advanced instrument for dosimetry systems. The EBT3 films are a new generation of Gafchromic films. Our main interest is to compare the response of the EBT3 films exposed to gamma rays provided by the Theratron 780C as a conventional radiotherapy system and the Leksell Gamma Knife as a stereotactic radiotherapy system (SRS). Both systems use Cobalt-60 sources, thus using the same energy. However, other factors such as source-to-axis distance, number of sources, dose rate, direction of irradiation, shape of phantom, the field shape of radiation, and different scatter contribution may influence the calibration curve...
May 17, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28514899/clinical-positioning-accuracy-for-multisession-stereotactic-radiotherapy-with-the-gamma-knife-perfexion
#15
Wade P Smith, Lori A Young, Mark H Phillips, Michael Cheung, Lia M Halasz, Jason K Rockhill
Multisession stereotactic radiation therapy is increasingly being seen as a preferred option for intracranial diseases in close proximity to critical structures and for larger target volumes. The objective of this study is to investigate the reproducibility of the Extend system from Elekta. A retrospective review was conducted for all patients treated with multisession Gamma Knife between July 2010 and June 2015, including both malignant and benign lesions. Eighty-four patients were treated in this 5-year span...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28513854/verification-of-dose-profiles-generated-by-the-convolution-algorithm-of-the-gamma-knife-%C3%A2-radiosurgery-planning-system
#16
Hyun-Tai Chung, Jeong-Hoon Park, Kook Jin Chun
PURPOSE: A convolution algorithm that takes into account electron-density inhomogeneity was recently introduced to calculate dose distributions for the Gamma Knife (GK) Perfexion(™) treatment planning program. The accuracies of the dose distributions computed using the convolution method were assessed using an anthropomorphic phantom and film dosimetry. METHODS: Absorbed-dose distributions inside a phantom (CIRS Radiosurgery Head Phantom, Model 605) were calculated using the convolution method of the GK treatment-planning software (Leksell Gamma Plan(®) version 10...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28503363/focused-ultrasound-for-essential-tremor-review-of-the-evidence-and-discussion-of-current-hurdles
#17
REVIEW
Mohammad Rohani, Alfonso Fasano
BACKGROUND: While there is no breakthrough progress in the medical treatment of essential tremor (ET), in the past decades several remarkable achievements happened in the surgical field, such as radiofrequency thalamotomy, thalamic deep brain stimulation, and gamma knife thalamotomy. The most recent advance in this area is magnetic resonance-guided focused ultrasound (MRgFUS). METHODS: The purpose of this review is to discuss the new developments and trials of MRgFUS in the treatment of ET and other tremor disorders...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28465265/stereotactic-radiosurgery-for-dural-carotid-cavernous-sinus-fistulas
#18
Seong-Hyun Park, Ki-Su Park, Dong-Hun Kang, Jeong-Hyun Hwang, Sung-Kyoo Hwang
OBJECTIVE: We reviewed our 7-year experience to assess the efficacy of stereotactic radiosurgery (SRS) for dural carotid cavernous fistulas (DCCFs). We analyzed the clinical outcome, complications and angiographic results. METHODS: We performed a retrospective analysis of 18 consecutive patients with DCCF treated by SRS alone using Gamma Knife between 2009 and 2015. Median target volume was 2.6 cm(3) (range, 0.6-11.6 cm(3)) and median radiation dose to the target was 17 Gy (range, 14-19 Gy)...
April 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28431024/radiosurgery-for-unruptured-brain-arteriovenous-malformations-an-international-multicenter-retrospective-cohort-study
#19
Dale Ding, Robert M Starke, Hideyuki Kano, John Y K Lee, David Mathieu, John Pierce, Paul Huang, Symeon Missios, Caleb Feliciano, Rafael Rodriguez-Mercado, Luis Almodovar, Inga S Grills, Danilo Silva, Mahmoud Abbassy, Douglas Kondziolka, Gene H Barnett, L Dade Lunsford, Jason P Sheehan
BACKGROUND: The role of intervention in the management of unruptured brain arteriovenous malformations (AVM) is controversial. OBJECTIVE: To analyze in a multicenter, retrospective cohort study, the outcomes following radiosurgery for unruptured AVMs and determine predictive factors. METHODS: We evaluated and pooled AVM radiosurgery data from 8 institutions participating in the International Gamma Knife Research Foundation. Patients with unruptured AVMs and ≥12 mo of follow-up were included in the study cohort...
June 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28425047/can-anti-vascular-endothelial-growth-factor-antibody-reverse-radiation-necrosis-a-preclinical-investigation
#20
Chong Duan, Carlos J Perez-Torres, Liya Yuan, John A Engelbach, Scott C Beeman, Christina I Tsien, Keith M Rich, Robert E Schmidt, Joseph J H Ackerman, Joel R Garbow
Anti-vascular endothelial growth factor (anti-VEGF) antibodies are a promising new treatment for late time-to-onset radiation-induced necrosis (RN). We sought to evaluate and validate the response to anti-VEGF antibody in a mouse model of RN. Mice were irradiated with the Leksell Gamma Knife Perfexion™ and then treated with anti-VEGF antibody, beginning at post-irradiation (PIR) week 8. RN progression was monitored via anatomic and diffusion MRI from weeks 4-12 PIR. Standard histology, using haematoxylin and eosin (H&E), and immunohistochemistry staining were used to validate the response to treatment...
April 19, 2017: Journal of Neuro-oncology
keyword
keyword
45011
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"