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https://www.readbyqxmd.com/read/28339986/the-national-association-of-social-workers-code-of-ethics-and-cultural-competence-what-does-anne-fadiman-s-the-spirit-catches-you-and-you-fall-down-teach-us-today
#1
Haylee Hebenstreit
This article discusses limitations in the National Association of Social Workers (NASW) Code of Ethics conceptualization of "cultural competence." It uses the case example presented in Anne Fadiman's classic (2012) work, The Spirit Catches You and You Fall Down: A Hmong Child, Her American Doctors, and the Collision of Two Cultures, to explore the conventional markers of cultural competence, as taught in contemporary graduate-level social work education curricula, and their implications for socially just practice...
March 4, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28338893/site-directed-mutant-libraries-for-isolating-minimal-mutations-yielding-functional-changes
#2
Dong Hee Chung, Sarah C Potter, Ammon C Tanomrat, Krishnakumar M Ravikumar, Michael D Toney
Powerful, facile new ways to create libraries of site-directed mutants are demonstrated. These include: (1) one-pot-PCR, (2) multi-pot-PCR, and (3) split-mix-PCR. One-pot-PCR uses mutant oligonucleotides to generate megaprimers in situ, and it was used to randomly incorporate 28 mutations in a gabT gene in a single reaction. In more difficult cases, multi-pot-PCR can be employed: mutant megaprimers are synthesized individually, then combined in a single mutagenesis PCR. This method was used to incorporate 14 out of 15 mutations in a pabB gene...
March 9, 2017: Protein Engineering, Design & Selection: PEDS
https://www.readbyqxmd.com/read/28332585/topology-optimisation-of-wideband-coaxial-to-waveguide-transitions
#3
Emadeldeen Hassan, Daniel Noreland, Eddie Wadbro, Martin Berggren
To maximize the matching between a coaxial cable and rectangular waveguides, we present a computational topology optimisation approach that decides for each point in a given domain whether to hold a good conductor or a good dielectric. The conductivity is determined by a gradient-based optimisation method that relies on finite-difference time-domain solutions to the 3D Maxwell's equations. Unlike previously reported results in the literature for this kind of problems, our design algorithm can efficiently handle tens of thousands of design variables that can allow novel conceptual waveguide designs...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28332404/conceptual-design-and-implantation-of-an-external-fixator-with-improved-mobility-for-knee-rehabilitation
#4
Gianluca Gatti
A hinged external fixator is used to allow early knee rehabilitation in case of injury or trauma, as an alternative approach to immobilization. It is mainly adopted for the treatment of dislocations, which involve tearing of the ligaments, and it basically consists of two links connected to each other by a revolute joint. Each link is fixed to the femur and tibia via pin fixation, and the revolute joint is approximately aligned to the knee flexion-extension (FE) axis. The advantage in its implantation is to protect ligament reconstruction, while allowing for an aggressive rehabilitation...
March 23, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28331596/credit-of-ecological-interactions-a-new-conceptual-framework-to-support-conservation-in-a-defaunated-world
#5
Luísa Genes, Bruno Cid, Fernando A S Fernandez, Alexandra S Pires
As defaunation spreads through the world, there is an urgent need for restoring ecological interactions, thus assuring ecosystem processes. Here, we define the new concept of credit of ecological interactions, as the number of interactions that can be restored in a focal area by species colonization or reintroduction. We also define rewiring time, as the time span until all the links that build the credit of ecological interactions of a focal area have become functional again. We expect that the credit will be gradually cashed following refaunation in rates that are proportional to (1) the abundance of the reintroduced species (that is expected to increase in time since release), (2) the abundance of the local species that interact with them, and (3) the traits of reintroduced species...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28330453/a-systematic-review-of-primary-care-models-for-non-communicable-disease-interventions-in-sub-saharan-africa
#6
Jennifer Kane, Megan Landes, Christopher Carroll, Amy Nolen, Sumeet Sodhi
BACKGROUND: Chronic diseases, primarily cardiovascular disease, respiratory disease, diabetes and cancer, are the leading cause of death and disability worldwide. In sub-Saharan Africa (SSA), where communicable disease prevalence still outweighs that of non-communicable disease (NCDs), rates of NCDs are rapidly rising and evidence for primary healthcare approaches for these emerging NCDs is needed. METHODS: A systematic review and evidence synthesis of primary care approaches for chronic disease in SSA...
March 23, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28329800/characterizing-readiness-for-advance-care-planning-from-the-perspective-of-residents-families-and-clinicians-an-interpretive-descriptive-study-in-supportive-living
#7
Marta Shaw, Jennifer Hewson, David B Hogan, Shelley Raffin Bouchal, Jessica Simon
Background and Objectives: Advance care planning (ACP) involves reflection on health care preferences and communication of the person's wishes in case of future incapacity. ACP is particularly pertinent in supportive living (SL) as residents are at high risk of cognitive decline and changes in health status, but the readiness of residents, families, and health care practitioners to engage in ACP discussions is not known. The purpose of this study was to explore the readiness among these stakeholders and the factors that influence the degree of readiness...
February 18, 2017: Gerontologist
https://www.readbyqxmd.com/read/28329431/an-analytical-method-for-groundwater-inflow-into-a-drained-circular-tunnel
#8
Kai Su, Yafeng Zhou, Hegao Wu, Changzheng Shi, Li Zhou
Groundwater inflow estimation is essential for the design and construction of tunnel and the assessment of the environmental impacts. Analytical solutions used in current engineering practice do not adequately account for the effect of the excavation-induced drawdown, which leads to significant change in pore water pressure distribution and reductions of the water level beyond tunnel. Based on the numerical analysis results, this article proposes semianalytical method to predict the height of lowered water level and groundwater tunnel inflow...
March 22, 2017: Ground Water
https://www.readbyqxmd.com/read/28328546/temporal-patterns-and-drug-resistance-in-csf-viral-escape-among-art-experienced-hiv-1-infected-adults
#9
Shibani S Mukerji, Vikas Misra, David Lorenz, Anna M Cervantes-Arslanian, Jennifer Lyons, Spyridon Chalkias, Alysse Wurcel, Deirdre Burke, Nagagopal Venna, Susan Morgello, Igor J Koralnik, Dana Gabuzda
BACKGROUND: Cerebrospinal fluid (CSF) viral escape is an increasingly recognized clinical event among HIV-1-infected adults. We analyzed longitudinal data and drug-resistance mutations to characterize profiles of HIV-1-infected patients on antiretroviral therapy with discordant CSF and plasma HIV-1 RNA levels. METHODS: Forty-one cases of CSF escape defined as detectable CSF HIV-1 RNA when plasma levels were undetectable, or HIV-1 RNA >0.5-log higher in CSF than plasma, were identified from Boston Hospitals and National NeuroAIDS Tissue Consortium (NNTC) from 2005-2016...
March 21, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28326032/a-dynamic-circuit-hypothesis-for-the-pathogenesis-of-blepharospasm
#10
David A Peterson, Terrence J Sejnowski
Blepharospasm (sometimes called "benign essential blepharospasm," BEB) is one of the most common focal dystonias. It involves involuntary eyelid spasms, eye closure, and increased blinking. Despite the success of botulinum toxin injections and, in some cases, pharmacologic or surgical interventions, BEB treatments are not completely efficacious and only symptomatic. We could develop principled strategies for preventing and reversing the disease if we knew the pathogenesis of primary BEB. The objective of this study was to develop a conceptual framework and dynamic circuit hypothesis for the pathogenesis of BEB...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28321873/disintegration-of-the-self-and-the-regeneration-of-psychic-skin-in-the-treatment-of-traumatized-refugees
#11
Monica Luci
This paper presents a tentative understanding of the characteristics of the extreme traumas, elsewhere called 'complex PTSD', that some refugees and asylum-seekers bring into therapy. It suggests that these kinds of traumas suffered during adulthood may involve a disintegration of the self and a loss of 'psychic skin'. This conceptualization is derived from the treatment of a refugee who survived multiple extreme traumas and with whom efforts were made in therapy to identify a complex methodology making use of supplementary therapeutic tools in addition to individual psychotherapy...
April 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28314191/robust-detection-and-segmentation-of-cell-nuclei-in-biomedical-images-based-on-a-computational-topology-framework
#12
Rodrigo Rojas-Moraleda, Wei Xiong, Niels Halama, Katja Breitkopf-Heinlein, Steven Dooley, Luis Salinas, Dieter W Heermann, Nektarios A Valous
The segmentation of cell nuclei is an important step towards the automated analysis of histological images. The presence of a large number of nuclei in whole-slide images necessitates methods that are computationally tractable in addition to being effective. In this work, a method is developed for the robust segmentation of cell nuclei in histological images based on the principles of persistent homology. More specifically, an abstract simplicial homology approach for image segmentation is established. Essentially, the approach deals with the persistence of disconnected sets in the image, thus identifying salient regions that express patterns of persistence...
March 6, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28314131/indicators-role-how-do-they-influence-strategic-environmental-assessment-and-sustainable-planning-the-chinese-experience
#13
Jingjing Gao, Per Christensen, Lone Kørnøv
As an information carrier and communication medium, indicators provide useful decision-making assistance in setting process goals and effectively reaching the goals. The main focus of this article is to investigate indicators' role in influencing planning through Strategic Environmental Assessment (SEA) especially related to Chinese experiences. From the perspective of planning and decision-making theory, the influence on planning is studied as influence of planning structure and influence of planning actors...
March 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28306628/pediatric-spinal-cord-injury-without-radiographic-abnormality-in-the-era-of-advanced-imaging
#14
Caitlin A Farrell, Megan Hannon, Lois K Lee
PURPOSE OF REVIEW: The current review describes the current evidence on pediatric spinal cord injury without radiographic abnormality (SCIWORA) with attention to the definition, epidemiology, and clinical presentation of the condition, as well as common MRI findings, management strategies, and outcomes. RECENT FINDINGS: Recent literature demonstrates that with more widespread MRI use, our understanding of SCIWORA has improved. The new literature, although still limited, provides a more granular conceptualization of patterns of injury as well as potential prognostic stratification of patients based on MRI findings...
March 16, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28300946/kraepelin-s-views-on-obsessive-neurosis-a-comparison-with-dsm-5-criteria-for-obsessive-compulsive-disorder
#15
Holger Steinberg, Dirk Carius, Leonardo F Fontenelle
Emil Kraepelin (1856-1926) is considered one of the founders of modern psychiatric nosology. However, his conceptualization of obsessive-compulsive phenomena is relatively understudied. In this article, we compare and contrast excerpts from the eighth edition (1909-1915) of Kraepelin's Textbook of Clinical Psychiatry focusing on what Kraepelin called "obsessive neurosis" and related "original pathological conditions" with the current DSM-5 criteria for obsessive-compulsive disorder (OCD). Consistently with DSM-5 OCD, Kraepelin described obsessive neurosis as characterized by obsessive ideas, compulsive acts, or both together...
March 13, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28296182/endothelial-progenitors-a-consensus-statement-on-nomenclature
#16
EDITORIAL
Reinhold J Medina, Chad L Barber, Florence Sabatier, Francoise Dignat-George, Juan M Melero-Martin, Kiarash Khosrotehrani, Osamu Ohneda, Anna M Randi, Jerry K Y Chan, Teruhide Yamaguchi, Victor W M Van Hinsbergh, Mervin C Yoder, Alan W Stitt
Endothelial progenitor cell (EPC) nomenclature remains ambiguous and there is a general lack of concordance in the stem cell field with many distinct cell subtypes continually grouped under the term "EPC." It would be highly advantageous to agree standards to confirm an endothelial progenitor phenotype and this should include detailed immunophenotyping, potency assays, and clear separation from hematopoietic angiogenic cells which are not endothelial progenitors. In this review, we seek to discourage the indiscriminate use of "EPCs," and instead propose precise terminology based on defining cellular phenotype and function...
March 10, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28294522/a-quantitative-screening-level-approach-to-incorporate-chemical-exposure-and-risk-safety-into-alternative-assessment-evaluations
#17
Scott M Arnold, Bill Greggs, Katy O Goyak, Bryce D Landenberger, Ann M Mason, Brett Howard, Rosemary Zaleski, Brett Howard, Rosemary T Zaleski
As the general public and retailers ask for disclosure of chemical ingredients in the marketplace, a number of hazard screening tools were developed to evaluate the so called "greenness" of individual chemical ingredients and/or formulations. The majority of these tools focus only on hazard, often using chemical lists, ignoring the other part of the risk equation: exposure. Using a hazard-only focus can result in regrettable substitutions, changing one chemical ingredient for another that turns out to be more hazardous or shifts the toxicity burden to others...
March 10, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28292594/the-management-of-boys-under-3-months-of-age-with-an-inguinal-hernia-and-ipsilateral-palpable-undescended-testis
#18
Naomi J Wright, Joseph R Davidson, Christina Major, Natalie Durkin, Yew-Wei Tan, Matthew Jobson, Niyi Ade-Ajayi, Nigel J Hall, Nordeen Bouhadiba
AIMS: The optimal management for boys under 3 months of age with an indirect inguinal hernia (IIH) and ipsilateral palpable undescended testis (IPUDT) is unknown. We aimed to: 1) determine the current practice for managing these boys across the UK, and 2) compare outcomes of different treatment strategies. METHODOLOGY: We undertook two studies. Firstly, we completed a National Survey of all surgeons on the British Association of Paediatric Surgeons email list in 2014...
March 6, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28290273/from-the-ebm-pyramid-to-the-greek-temple-a-new-conceptual-approach-to-guidelines-as-implementation-tools-in-mental-health
#19
L Salvador-Carulla, S Lukersmith, W Sullivan
Guideline methods to develop recommendations dedicate most effort around organising discovery and corroboration knowledge following the evidence-based medicine (EBM) framework. Guidelines typically use a single dimension of information, and generally discard contextual evidence and formal expert knowledge and consumer's experiences in the process. In recognition of the limitations of guidelines in complex cases, complex interventions and systems research, there has been significant effort to develop new tools, guides, resources and structures to use alongside EBM methods of guideline development...
April 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28289251/the-evolution-of-transmission-mode
#20
REVIEW
Janis Antonovics, Anthony J Wilson, Mark R Forbes, Heidi C Hauffe, Eva R Kallio, Helen C Leggett, Ben Longdon, Beth Okamura, Steven M Sait, Joanne P Webster
This article reviews research on the evolutionary mechanisms leading to different transmission modes. Such modes are often under genetic control of the host or the pathogen, and often in conflict with each other via trade-offs. Transmission modes may vary among pathogen strains and among host populations. Evolutionary changes in transmission mode have been inferred through experimental and phylogenetic studies, including changes in transmission associated with host shifts and with evolution of the unusually complex life cycles of many parasites...
May 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
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