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https://www.readbyqxmd.com/read/28545206/the-performance-of-an-efficient-dairy-system-using-a-combination-of-nitrogen-leaching-mitigation-strategies-in-a-variable-climate
#1
P C Beukes, A J Romera, P Gregorini, K A Macdonald, C B Glassey, M A Shepherd
An efficient dairy system, that implemented a combination of nitrogen (N) leaching mitigation strategies including lower N fertilizer input, standing cows off pasture for part of the day in autumn and winter (stand-off), and importing limited amounts of low protein supplements was evaluated over four consecutive years of a farmlet study. This efficient system consistently demonstrated a lower measured annual N leaching of 40 to 50% compared with a baseline system representing current practice with no mitigations...
May 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28543882/risk-factors-for-burnout-among-caregivers-working-in-nursing-homes
#2
Nadia Kandelman, Thierry Mazars, Antonin Levy
AIMS AND OBJECTIVES: Our objectives were a) to assess the level of burnout in nursing home caregivers within a unique healthcare network in France and b) to evaluate potential risk factors in this population. BACKGROUND: Burnout syndrome occurs frequently among nursing home caregivers, and has strong detrimental effects on the quality of health care for residents. DESIGN: We used an observational survey to study burnout in nursing home caregivers...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28543414/closed-financial-loops-when-they-happen-in-government-they-re-called-corruption-in-medicine-they-re-just-a-footnote
#3
Kevin De Jesus-Morales, Vinay Prasad
Many physicians are involved in relationships that create tension between a physician's duty to work in her patients' best interest at all times and her financial arrangement with a third party, most often a pharmaceutical manufacturer, whose primary goal is maximizing sales or profit. Despite the prevalence of this threat, in the United States and globally, the most common reaction to conflicts of interest in medicine is timid acceptance. There are few calls for conflicts of interest to be banned, and, to our knowledge, no one calls for conflicted practitioners to be reprimanded...
May 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28539932/genotype-dependent-interaction-of-lentil-lines-with-ascochyta-lentis
#4
Ehsan Sari, Vijai Bhadauria, Albert Vandenberg, Sabine Banniza
Ascochyta blight of lentil is a prevalent disease in many lentil producing regions and can cause major yield and grain quality losses. The most environmentally acceptable and economically profitable method of control is to develop varieties with high levels of durable resistance. Genetic studies to date suggest that ascochyta blight resistance genes (R-gene) in lentil lines CDC Robin, ILL 7537, 964a-46, and ILL 1704 are non-allelic. To understand how different R-genes manifest resistance in these genotypes and an accession of Lens ervoides, L-01-827A, with high level of resistance to ascochyta blight, cellular and molecular defense responses were compared after inoculation with the causal pathogen Ascochyta lentis...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28539107/a-feasibility-study-of-municipal-solid-waste-incineration-fly-ash-utilisation-in-estonia
#5
Hakan Berber, Ruedi Frey, Viktoria Voronova, Arina Koroljova
The purpose of this paper is to discuss the alternative environmental management options for the utilisation of municipal solid waste (MSW) incineration fly ash (FA), which is generated at Iru Power Plant where MSW is incinerated in Estonia. To determine sustainable and economically feasible environmental management options for MSW incineration FA in Estonia, CO2 sequestration with a further carbonation process was examined. A partial Cost & Benefit Analysis has been conducted to compare the carbonation process to the current situation...
May 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28536450/sustainability-is-possible-despite-greed-exploring-the-nexus-between-profitability-and-sustainability-in-common-pool-resource-systems
#6
Friedrich Burkhard von der Osten, Michael Kirley, Tim Miller
The sustainable use of common pool resources has become a significant global challenge. It is now widely accepted that specific mechanisms such as community-based management strategies, institutional responses such as resource privatization, information availability and emergent social norms can be used to constrain individual 'harvesting' to socially optimal levels. However, there is a paucity of research focused specifically on aligning profitability and sustainability goals. In this paper, an integrated mathematical model of a common pool resource game is developed to explore the nexus between the underlying costs and benefits of harvesting decisions and the sustainable level of a shared, dynamic resource...
May 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536135/fair-pricing-or-pricing-for-profit
#7
Barbara Sibbald
No abstract text is available yet for this article.
May 23, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28535753/anxiety-and-depression-symptoms-and-alcohol-use-among-adolescents-%C3%A2-a-cross-sectional-study-of-norwegian-secondary-school-students
#8
Espen Lund Johannessen, Helle Wessel Andersson, Johan Håkon Bjørngaard, Kristine Pape
BACKGROUND: We investigated the associations between symptoms of anxiety and depression and alcohol drinking behavior among adolescents, by focusing on the importance of symptom load, as well as gender differences. METHODS: Data was derived from a cross-sectional school based survey among adolescents in upper secondary schools in Norway. Among other variables adolescents reported on symptoms of anxiety and depression, time of onset and extent of alcohol use. The sample consisted of 6238 adolescents aged 16-18 years...
May 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28533760/the-role-of-prosocialness-and-trust-in-the-consumption-of-water-as-a-limited-resource
#9
Esther Cuadrado, Carmen Tabernero, Rocío García, Bárbara Luque, Jan Seibert
This research analyzes the role of prosocialness and trust in the use of water as a limited resource under situations of competition or cooperation. For this purpose, 107 participants played the role of farmers and made decisions about irrigating their fields in the web-based multiplayer game Irrigania. Before the simulation exercise, participants' prosocialness and trust levels were evaluated and they were randomly assigned to an experimental condition (competition or cooperation). Repeated measures analysis, using the 10 fields and the experimental conditions as factors, showed that, in the cooperation condition, farmers and their villages used a less selfish strategy to cultivate their fields, which produced greater benefits...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28533059/graft-versus-host-disease-of-the-gut-a-histologic-activity-grading-system-and-validation
#10
David Myerson, Gideon Steinbach, Ted A Gooley, Howard M Shulman
The pathologic interpretation of gut biopsies in hematopoietic cell transplant recipients to assess graft-versus-disease (GVHD) is well accepted and supplements clinical and endoscopic findings. However, the histologic activity grading of GVHD is controversial, with attempts to predict prognosis or response to treatment largely unsuccessful. GVHD is being diagnosed earlier in its course, raising the possibility that the pathologic grading system can be profitably modified. We have developed a histologic activity grading system designed to replace the commonly used modified-Lerner grading systems...
May 19, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28531772/diet-induced-weight-loss-and-markers-of-endothelial-dysfunction-and-inflammation-in-treated-patients-with-type-2-diabetes
#11
K A Berk, T P Oudshoorn, A J M Verhoeven, M T Mulder, A J M Roks, W A Dik, R Timman, E J G Sijbrands
BACKGROUND & AIMS: Overweight and obesity increase cardiovascular mortality in patients with type 2 diabetes (T2D). In a recent trial, however, diet-induced weight loss did not reduce the cardiovascular risk of patients with T2D, possibly due to the parallel intensive medical treatment. We investigated the effect of diet-induced weight loss on cardiovascular risk factors in overweight and obese patients with T2D, and whether this effect was influenced by the use of statins, ACE inhibitors, metformin and duration of T2D...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28529703/prima-facie-reasons-to-question-enclosed-intellectual-property-regimes-and-favor-open-source-regimes-for-germplasm
#12
Madeleine-Thérèse Halpert, M Jahi Chappell
In principle, intellectual property protections (IPPs) promote and protect important but costly investment in research and development. However, the empirical reality of IPPs has often gone without critical evaluation, and the potential of alternative approaches to lend equal or greater support for useful innovation is rarely considered. In this paper, we review the mounting evidence that the global intellectual property regime (IPR) for germplasm has been neither necessary nor sufficient to generate socially beneficial improvements in crop plants and maintain agrobiodiversity...
2017: F1000Research
https://www.readbyqxmd.com/read/28529099/the-value-of-comparative-research-in-major-day-surgery
#13
Alba Llop-Gironés, Montse Vergara-Duarte, Josep Anton Sánchez, Gemma Tarafa, Joan Benach
OBJECTIVE: To measure time trends in major day surgery rates according to hospital ownership and other hospital characteristics among the providers of the public healthcare network of Catalonia, Spain. METHOD: Data from the Statistics of Health Establishments providing Inpatient Care. A generalized linear mixed model with Gaussian response and random intercept and random slopes. RESULTS: The greatest growth in the rate of major day surgery was observed among private for-profit hospitals: 42...
May 19, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28527794/farmers-preferences-for-automatic-lameness-detection-systems-in-dairy-cattle
#14
T Van De Gucht, W Saeys, A Van Nuffel, L Pluym, K Piccart, L Lauwers, J Vangeyte, S Van Weyenberg
As lameness is a major health problem in dairy herds, a lot of attention goes to the development of automated lameness-detection systems. Few systems have made it to the market, as most are currently still in development. To get these systems ready for practice, developers need to define which system characteristics are important for the farmers as end users. In this study, farmers' preferences for the different characteristics of proposed lameness-detection systems were investigated. In addition, the influence of sociodemographic and farm characteristics on farmers' preferences was assessed...
May 17, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28527671/inferences-about-moral-character-moderate-the-impact-of-consequences-on-blame-and-praise
#15
Jenifer Z Siegel, Molly J Crockett, Raymond J Dolan
Moral psychology research has highlighted several factors critical for evaluating the morality of another's choice, including the detection of norm-violating outcomes, the extent to which an agent caused an outcome, and the extent to which the agent intended good or bad consequences, as inferred from observing their decisions. However, person-centered accounts of moral judgment suggest that a motivation to infer the moral character of others can itself impact on an evaluation of their choices. Building on this person-centered account, we examine whether inferences about agents' moral character shape the sensitivity of moral judgments to the consequences of agents' choices, and agents' role in the causation of those consequences...
May 17, 2017: Cognition
https://www.readbyqxmd.com/read/28526075/testing-times-trends-in-availability-price-and-market-share-of-malaria-diagnostics-in-the-public-and-private-healthcare-sector-across-eight-sub-saharan-african-countries-from-2009-to-2015
#16
Kara Hanson, Catherine Goodman
BACKGROUND: The World Health Organization guidelines have recommended that all cases of suspected malaria should receive a confirmatory test with microscopy or a malaria rapid diagnostic test (RDT), however evidence from sub-Saharan Africa (SSA) illustrates that only one-third of children under five with a recent fever received a test. The aim of this study was to evaluate availability, price and market share of microscopy and RDT from 2009/11 to 2014/15 in 8 SSA countries, to better understand barriers to improving access to malaria confirmatory testing in the public and private health sectors...
May 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28523823/cost-benefit-analysis-of-controlling-the-spotted-wing-drosophila-drosophila-suzukii-matsumura-spread-and-infestation-of-soft-fruits-in-trentino-northern-italy
#17
Emanuele Del Fava, Claudio Ioriatti, Alessia Melegaro
BACKGROUND: We assessed the economic impact of the invasive pest Drosophila suzukii (Matsumura) on the soft fruit industry (strawberries, raspberries, blackberries, and blueberries) in Trentino, Northern Italy, using cost-benefit analysis. A conventional integrated pest management (IPM) based on insecticide, mass trapping and cultural measures is compared to an upgraded IPM strategy based on exclusion netting. Costs and benefits associated with the change between the two are estimated in order to evaluate the most profitable strategy from the societal point of view...
May 19, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28523115/discovery-of-fevipiprant-nvp-qaw039-a-potent-and-selective-dp2-receptor-antagonist-for-treatment-of-asthma
#18
David A Sandham, Lucy Barker, Lyndon Brown, Zarin Brown, David Budd, Steven J Charlton, Devnandan Chatterjee, Brian Cox, Gerald Dubois, Nicholas Duggan, Edward Hall, Julia Hatto, Janet Maas, Jodie Manini, Rachael Profit, Darren Riddy, Catherine Ritchie, Bindi Sohal, Duncan Shaw, Rowan Stringer, David A Sykes, Matthew Thomas, Katharine L Turner, Simon J Watson, Ryan West, Elisabeth Willard, Gareth Williams, Jennifer Willis
Further optimization of an initial DP2 receptor antagonist clinical candidate NVP-QAV680 led to the discovery of a follow-up molecule 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (compound 11, NVP-QAW039, fevipiprant), which exhibits improved potency on human eosinophils and Th2 cells, together with a longer receptor residence time, and is currently in clinical trials for severe asthma.
May 11, 2017: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28521336/chemical-ecology-of-antibiotic-production-by-actinomycetes
#19
Anne van der Meij, Sarah F Worsley, Matthew I Hutchings, Gilles P van Wezel
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural products relevant for agriculture, biotechnology and medicine, including the majority of the antibiotics we use in the clinic. Rather than as free-living bacteria, many actinomycetes have evolved to live in symbiosis with among others plants, fungi, insects and sponges. As a common theme, these organisms profit from the natural products and enzymes produced by the actinomycetes, for example, for protection against pathogenic microbes, for growth promotion or for the degradation of complex natural polymers such as lignocellulose...
May 1, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28518283/branched-chain-amino-acids-for-people-with-hepatic-encephalopathy
#20
REVIEW
Lise Lotte Gluud, Gitte Dam, Iñigo Les, Giulio Marchesini, Mette Borre, Niels Kristian Aagaard, Hendrik Vilstrup
BACKGROUND: Hepatic encephalopathy is a brain dysfunction with neurological and psychiatric changes associated with liver insufficiency or portal-systemic shunting. The severity ranges from minor symptoms to coma. A Cochrane systematic review including 11 randomised clinical trials on branched-chain amino acids (BCAA) versus control interventions has evaluated if BCAA may benefit people with hepatic encephalopathy. OBJECTIVES: To evaluate the beneficial and harmful effects of BCAA versus any control intervention for people with hepatic encephalopathy...
May 18, 2017: Cochrane Database of Systematic Reviews
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