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Ghadi Mohammed Al Hashan, Nagah Mohamed Abo El-Fetoh, Iman Ali Nasser, Atheer Raja Alyami, Albatool Saleh Hassan Almagbool, Taghreed Ahmad Eidih Hatuwh, Fatimah Hamad Saleh Alyami, Maram Hamad Al Yami, Manar Hamad Alqahtani, Nouf Mubarak Ali Almardhamah, Tahani Mohammed Alanazi, Wafaa Mohamed Bakr Ali, Ahad Mesfer Halzaa, Ayah Abdullah Alshehri
Background: With more than 500,000 new cases annually, human brucellosis is the commonest zoonotic disease worldwide. In some endemic countries, its prevalence is more than 10 per 100,000 population. Objective: The aim of this study was to determine the magnitude of the problem and the clinical features, laboratory findings, treatment given and complications seen in children with brucellosis in Najran City, Kingdom of Saudi Arabia. Methods: This is a case-series study by analysis of data of children known or diagnosed to have brucellosis for the last 4 years in Najran City...
December 2017: Electronic Physician
Ali H El-Far, Babatunji Emmanuel Oyinloye, Masood Sepehrimanesh, Mahmoud A Gab Allah, Ibrahim Abu Reidah, Hazem M Shaheen, Iman Razeghian-Jahromi, Abd El-Wahab A Alsenosy, Ahmed E Noreldin, Soad K Al Jaouni, Shaker A Mousa
Phoenix dactylifera is a useful traditional medicinal plant, mainly the fruit is used, which is the edible part of the plant (Ajwa date). It is now considered to be a valuable source of natural medicinal products against various diseases. Phytochemical investigations have shown that the fruit contains anthocyanins, phenolics, sterols, carotenoids, and flavonoids. The fruits are a rich source of carbohydrates, vitamins, and proteins. P. dactylifera is considered as a complete diet because it also contains different fatty acids, amino acids, proteins, and steroidal substances...
March 19, 2018: Current Drug Discovery Technologies
Iman Khaoudy, Lionel Rebibo, Jean-Marc Regimbeau
No abstract text is available yet for this article.
April 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Kaoutar Laslami, Sara Dhoum, Amine El Harchi, Iman Benkiran
Objectives: The aim of the study is to define the relationship between the apical preparation diameter and the apical sealing ability to highlight the importance of the preservation of the diameter and the original position of the apical foramen. Materials and Methods: 50 extracted maxillary incisors were randomly allocated into three groups of 15 teeth each (n = 15) according to the apical preparation size: Group 1: finishing file F1 corresponding to size 20 reached the working length (ProTaper Universal system Dentsply®); Group 2: prepared up to size 30 corresponding to finishing file F30; Group 3: prepared up to size 50 corresponding to finishing file F5...
2018: International Journal of Dentistry
Lyle W Murray, Iman Satti, Jodi Meyerowitz, Matthew Jones, Christian B Willberg, James E Ussher, Dominique Goedhals, Jacob Hurst, Rodney E Phillips, Helen McShane, Cloete van Vuuren, John Frater
Background: Human immunodeficiency virus (HIV)-infected individuals have a higher risk of developing active tuberculosis (TB) than HIV-uninfected individuals, but the mechanisms underpinning this are unclear. We hypothesized that depletion of specific components of Mycobacterium tuberculosis (Mtb)-specific CD4+ and CD8+ T-cell responses contributed to this increased risk. Methods: Mtb-specific T-cell responses in 147 HIV-infected and 44 HIV-uninfected control subjects in a TB-endemic setting in Bloemfontein, South Africa, were evaluated...
March 13, 2018: Journal of Infectious Diseases
Francesca Mossa, Daniela Bebbere, Antonello Ledda, Giovanni P Burrai, Imane Chebli, Elisabetta Antuofermo, Sergio Ledda, Antonello Cannas, Francesco Fancello, Alberto S Atzori
Maternal nutrition during critical gestation periods impacts on offspring in later life; effects of high-starch maternal diet on testicular development in lambs were addressed. Dairy ewes were fed diets providing either 27% (Starch, S) or 11% (Fiber, F) of starch from mating to lambing (∼147 days; S147, F147) or for the last 75 days of gestation (S75, F75). Testes of single male lambs were measured and then sampled for histological and gene expression analyses at selected ages. Testicular dimensions and weight were similar among groups, but the total area of seminiferous tubules increased with age and tended to be higher (P = 0...
March 15, 2018: Molecular Reproduction and Development
Deborah J Bird, William J Murphy, Lester Fox-Rosales, Iman Hamid, Robert A Eagle, Blaire Van Valkenburgh
The evolution of mammalian olfaction is manifested in a remarkable diversity of gene repertoires, neuroanatomy and skull morphology across living species. Olfactory receptor genes (ORGs), which initiate the conversion of odorant molecules into odour perceptions and help an animal resolve the olfactory world, range in number from a mere handful to several thousand genes across species. Within the snout, each of these ORGs is exclusively expressed by a discrete population of olfactory sensory neurons (OSNs), suggesting that newly evolved ORGs may be coupled with new OSN populations in the nasal epithelium...
March 14, 2018: Proceedings. Biological Sciences
James L Kingsley, Jeffrey P Bibeau, S Iman Mousavi, Cem Unsal, Zhilu Chen, Xinming Huang, Luis Vidali, Erkan Tüzel
Fluorescence recovery after photobleaching (FRAP) is an important tool used by cell biologists to study the diffusion and binding kinetics of vesicles, proteins, and other molecules in the cytoplasm, nucleus, or cell membrane. Although many FRAP models have been developed over the past decades, the influence of the complex boundaries of 3D cellular geometries on the recovery curves, in conjunction with regions of interest and optical effects (imaging, photobleaching, photoswitching, and scanning), has not been well studied...
March 13, 2018: Biophysical Journal
Emma Hofstra, Iman Elfeddali, Marjan Bakker, Jacobus J de Jong, Chijs van Nieuwenhuizen, Christina M van der Feltz-Cornelis
Background: Time trends are one of the most studied phenomena in suicide research; however, evidence for time trends in the Dutch population remains understudied. Insight into time trends can contribute to the development of effective suicide prevention strategies. Methods: Time trends in national daily and monthly data of 33,224 suicide events that occurred in the Netherlands from 1995 to 2015 were examined, as well as the influence of age, gender, and province, in a longitudinal population-based design with Poisson regression analyses and Bayesian change point analyses...
2018: Frontiers in Psychiatry
H Abdella, M K Shaker, Iman Fawzy Montasser, M Sobhi, H Aly, A Sayed, S Saleh, A El Dorry
BACKGROUND/AIM: Portal vein tumor thrombosis (PVTT) is a common complication in hepatocellular carcinoma (HCC) and it was considered a relative contraindication for transarterial chemoembolization (TACE) by many centers. This study aimed to assess the outcomes after TACE in patients with branch PVT regarding Child classification, radiological response, and 1-year survival. METHODS: Thirty HCC patients (24 male, 6 females) Child A cirrhotics with branch PVT underwent TACE...
March 13, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Morteza Modarresi Asem, Iman Sheikh Oveisi, Mona Janbozorgi
Retinal blood vessels indicate some serious health ramifications, such as cardiovascular disease and stroke. Thanks to modern imaging technology, high-resolution images provide detailed information to help analyze retinal vascular features before symptoms associated with such conditions fully develop. Additionally, these retinal images can be used by ophthalmologists to facilitate diagnosis and the procedures of eye surgery. A fuzzy noise reduction algorithm was employed to enhance color images corrupted by Gaussian noise...
July 2018: Journal of Medical Imaging
Bassant Meligy, Dalia Kadry, Iman H Draz, Huda Marzouk, Nevine R El Baroudy, Amira Sayed El Rifay
INTRODUCTION: Acute encephalitis syndrome (AES) is a considerable public health problem. AIM: This study was designed to describe the aetiology, demographic features, clinical picture, short-term outcome and risk factors of mortality of children with viral encephalitis in Egyptian children. METHODS: PCR detection of viruses in the CSF of pediatric patients admitted to the pediatric unit or ICU Cairo University Pediatric hospital presenting with encephalitis syndrome...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
Mahdi Abastabar, Abdullah M S Al-Hatmi, Mohammad Vafaei Moghaddam, G Sybren de Hoog, Iman Haghani, Seyed Reza Aghili, Tahereh Shokohi, Mohammad Taghi Hedayati, Roshanak Daie Ghazvini, Reza Kachuei, Ali Rezaei-Matehkolaei, Koichi Makimura, Jacques F Meis, Hamid Badali
A collection of clinical (n=47) and environmental (n=79) Fusarium isolates were tested against 10 antifungal drugs, including two novel imidazoles. Luliconazole and lanoconazole demonstrated very low GM MIC values of 0.005 μg/ml and 0.013 μg/ml, respectively, in comparison with 0.51 μg/ml for micafungin, 0.85 μg/ml for efinaconazole, 1.12 μg/ml for natamycin, 1.18 μg/ml for anidulafungin, 1.31 μg/ml for voriconazole, 1.35 μg/ml for caspofungin, 1.9 μg/ml for amphotericin B and 4.08 μg/ml for itraconazole...
March 12, 2018: Antimicrobial Agents and Chemotherapy
Iman I Salama, Samia M Sami, Zeinab N Said, Somaia I Salama, Thanaa M Rabah, Ghada A Abdel-Latif, Dalia M Elmosalami, Rehan M Saleh, Aida M Abdel Mohsin, Ammal M Metwally, Amal I Hassanin, Hanaa M Emam, Samia A Hemida, Safaa M Elserougy, Fatma A Shaaban, Walaa A Fouad, Amira Mohsen, Manal H El-Sayed
OBJECTIVE: To evaluate early and long term anamnestic response to a booster dose of HBV vaccine among non-seroprotected children. SUBJECTS AND METHOD: A national community based project was carried out on 3600 children aged 9 months to 16 years, fully vaccinated during infancy. They were recruited from 6 governorates representing Egypt. It revealed that 1535 children (42.8%) had non sero-protective anti-HBs (<10 IU/L) and were HBsAg or anti-HBc negative. A challenging dose of 10 μg of mono-valent Euvax HBV vaccine was given to 1121/1535 children...
March 9, 2018: Vaccine
Amal Bennani, Nassira Karich, Imane Kamaoui, Meryem Chraibi, Sanaa Abbaoui
BACKGROUND: Schwannomas are uncommon tumors of the external auditory canal. In the English literature, very few cases of schwannomas originating in the external auditory canal were reported and none of them showed chondroid metaplasia. We report the first case of schwannoma with chondroid metaplasia in this location. CASE PRESENTATION: In this report, we described a 22-year-old white man who presented with an external auditory slow growing mass. A computed tomography scan of the temporal bone demonstrated a well-circumscribed, soft tissue mass narrowing most of the external auditory canal...
March 13, 2018: Journal of Medical Case Reports
Imane Laraba, Abdelaziz Keddad, Houda Boureghda, Nora Abdallah, Martha M Vaughan, Robert H Proctor, Mark Busman, Kerry O'Donnell
A novel crown rot pathogen of wheat discovered during pathogen surveys in Algeria in 2014 and 2015 is formally described as Fusarium algeriense. Multilocus molecular phylogenetic data resolved the eight isolates of this pathogen as a genealogically exclusive species lineage in the F. burgessii species complex. The previously described species of this complex, F. burgessii and F. beomiforme, produce abundant chlamydospores in culture, and their optimal temperature for growth is 30 C. In comparison, F. algeriense did not produce chlamydospores under the conditions tested and its optimal temperature for growth is 25 C...
February 13, 2018: Mycologia
Sunwook Kim, Maury A Nussbaum, Mohammad Iman Mokhlespour Esfahani, Mohammad Mehdi Alemi, Saad Alabdulkarim, Ehsan Rashedi
Use of exoskeletal vests (designed to support overhead work) can be an effective intervention approach for tasks involving arm elevation, yet little is known on the potential beneficial impacts of their use on physical demands and task performance. This laboratory study (n = 12) evaluated the effects of a prototype exoskeletal vest during simulated repetitive overhead drilling and light assembly tasks. Anticipated or expected benefits were assessed, in terms of perceived discomfort, shoulder muscle activity, and task performance...
March 7, 2018: Applied Ergonomics
Sunwook Kim, Maury A Nussbaum, Mohammad Iman Mokhlespour Esfahani, Mohammad Mehdi Alemi, Bochen Jia, Ehsan Rashedi
Adopting a new technology (exoskeletal vest designed to support overhead work) in the workplace can be challenging since the technology may pose unexpected safety and health consequences. A prototype exoskeletal vest was evaluated for potential unexpected consequences with a set of evaluation tests for: usability (especially, donning & doffing), shoulder range of motion (ROM), postural control, slip & trip risks, and spine loading during overhead work simulations. Donning/doffing the vest was easily done by a wearer alone...
March 7, 2018: Applied Ergonomics
Imane Benabdelaziz, Santiago Gómez-Ruiz, Mohammed Benkhaled, Sandra Carralero, Patricia Schenker, Andrea Salm, Jürg Gertsch, Hamada Haba
From acetonic extract of the whole plant Euphorbia pterococca Brot. (Euphorbiaceae), four new cycloartane-type ester triterpenes named cycloartenyl-2'E,4'E-decadienoate (1), cycloartenyl-2'E,4'Z-decadienoate (2), 24-methylenecycloartanyl-2'E,4'Z-tetradecadienoate (3), and 24-oxo-29-norcycloartanyl-2'E,4'Z-hexadecadienoate (4) were obtained along with nine known tetracyclic triterpenes (5-13). Their structures were established mainly by extensive use of spectroscopic techniques, including 1D (1 H and13 C) and 2D homo- and heteronuclear NMR experiments (COSY, HSQC, HMBC and NOESY), and mass spectrometry (HRESIMS), and by comparison with data reported in the literature...
March 7, 2018: Fitoterapia
Stephanie A Harris, Andrew White, Lisa Stockdale, Rachel Tanner, Laura Sibley, Charlotte Sarfas, Joel Meyer, Jonathan Peter, Matthew K O'Shea, Zita-Rose Manjaly Thomas, Ali Hamidi, Iman Satti, Mike J Dennis, Helen McShane, Sally Sharpe
The lack of validated immunological correlates of protection makes tuberculosis vaccine development difficult and expensive. Using intradermal bacille Calmette-Guréin (BCG) as a surrogate for aerosol Mycobacterium tuberculosis (M.tb) in a controlled human infection model could facilitate vaccine development, but such a model requires preclinical validation. Non-human primates (NHPs) may provide the best model in which to do this. Cynomolgus and rhesus macaques were infected with BCG by intradermal injection...
January 2018: Tuberculosis
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