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Electroconvulsive ECT schizophrenia

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https://www.readbyqxmd.com/read/27824784/use-of-expert-consultation-in-a-complex-case-of-neuroleptic-malignant-syndrome-requiring-electroconvulsive-therapy
#1
Justine Wittenauer Welsh, A Umair Janjua, Steven J Garlow, Laurie McCormick, Mustafa M Husain, Daniel F Maixner, Richard D Weiner, Adriana P Hermida
Our team at Emory University Hospital contacted experts at the National Network of Depression Centers (NNDC) for clinical guidance concerning a patient with schizophrenia hospitalized in the intensive care unit with a complex case of prolonged delirium secondary to neuroleptic malignant syndrome (NMS). Through the NNDC, leading psychiatrists across the United States with expertise in electroconvulsive therapy (ECT) provided us with treatment strategies based on experience in our area of concern. This report describes our use of ECT to treat severe NMS in this patient with schizophrenia, utilizing the recommendations made by the NNDC's ECT experts concerning electrode position, number and frequency of treatments, and selection of anesthetic induction agents...
November 2016: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/27753759/electroconvulsive-therapy-in-schizophrenia-in-china-a-national-survey
#2
Qian Li, Yun-Ai Su, Yu-Tao Xiang, Liang Shu, Xin Yu, Gabor S Ungvari, Stephen J Seiner, Helen F K Chiu, Yu-Ping Ning, Gao-Hua Wang, Ke-Rang Zhang, Tao Li, Li-Zhong Sun, Jian-Guo Shi, Xian-Sheng Chen, Qi-Yi Mei, Ke-Qing Li, Tian-Mei Si
OBJECTIVE: Little is known about electroconvulsive therapy (ECT) use in the treatment of schizophrenia in China. This study examined the frequency of ECT use, its trend between 2006 and 2012, and its independent demographic and clinical correlates in a nationwide survey in China. METHODS: A total of 5162 inpatients in 45 Chinese psychiatric hospitals/centers were interviewed (2696 in 2006 and 2466 in 2012). Patients' sociodemographic and clinical characteristics were recorded using a standardized protocol and data collection procedure...
October 7, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27723522/electroconvulsive-therapy-and-its-relationships-with-clinical-characteristics-and-quality-of-life-in-chinese-psychiatric-patients
#3
Feng-Rong An, Ling Zhang, Qing-E Zhang, Gabor S Ungvari, Chee H Ng, Helen F K Chiu, Ping-Ping Wu, Xin Jin, Lu Li, Grace K I Lok, Yu-Tao Xiang
Little is known about the pattern of electroconvulsive therapy (ECT) use in the clinical population in China. This study examined the percentage of ECT use and its association with clinical characteristics and quality of life (QOL) in a psychiatric center in China that caters for a population of 20 million. A total sample of 1364 inpatients was consecutively recruited for the study. Demographic and clinical data including the use of ECT were collected. Psychopathology, activity of daily living and QOL were measured using standardized instruments...
September 28, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27663585/the-change-in-facial-emotion-recognition-ability-in-inpatients-with-treatment-resistant-schizophrenia-after-electroconvulsive-therapy
#4
Mihriban Dalkıran, Akif Tasdemir, Tamer Salihoglu, Murat Emul, Alaattin Duran, Mufit Ugur, Ruhi Yavuz
People with schizophrenia have impairments in emotion recognition along with other social cognitive deficits. In the current study, we aimed to investigate the immediate benefits of ECT on facial emotion recognition ability. Thirty-two treatment resistant patients with schizophrenia who have been indicated for ECT enrolled in the study. Facial emotion stimuli were a set of 56 photographs that depicted seven basic emotions: sadness, anger, happiness, disgust, surprise, fear, and neutral faces. The average age of the participants was 33...
September 23, 2016: Psychiatric Quarterly
https://www.readbyqxmd.com/read/27590010/electroconvulsive-shock-attenuated-microgliosis-and-astrogliosis-in-the-hippocampus-and-ameliorated-schizophrenia-like-behavior-of-gunn-rat
#5
Erlyn Limoa, Sadayuki Hashioka, Tsuyoshi Miyaoka, Keiko Tsuchie, Ryosuke Arauchi, Ilhamuddin A Azis, Rei Wake, Maiko Hayashida, Tomoko Araki, Motohide Furuya, Kristian Liaury, Andi J Tanra, Jun Horiguchi
BACKGROUND: Although electroconvulsive therapy (ECT) is regarded as one of the efficient treatments for intractable psychiatric disorders, the mechanism of therapeutic action remains unclear. Recently, many studies indicate that ECT affects the immune-related cells, such as microglia, astrocytes, and lymphocytes. Moreover, microglial activation and astrocytic activation have been implicated in the postmortem brains of schizophrenia patients. We previously demonstrated that Gunn rats showed schizophrenia-like behavior and microglial activation in their brains...
2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27428480/electroconvulsive-therapy-and-all-cause-mortality-in-texas-1998-2013
#6
Nora M Dennis, Paul A Dennis, Alan Shafer, Richard D Weiner, Mustafa M Husain
INTRODUCTION: Electroconvulsive therapy (ECT) remains an effective treatment for major depressive disorder. Since 1995, Texas has maintained an ECT database including patient diagnoses and outcomes, and reporting any deaths within 14 days of receiving an ECT treatment, encompassing a total of 166,711 ECT treatments administered in Texas over the previously unreported period of 1998 to 2013. METHODS: Descriptive analysis summarized information on deaths reported during the 16-year period-cause of death, type of treatment (index or maintenance) and patient demographics...
July 16, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27428477/adjunctive-electroconvulsive-therapy-for-schizophrenia-a-meta-analysis-of-randomized-rater-masked-controlled-trials-retracted
#7
Wei Zheng, Yu-Tao Xiang, Yi-Lang Tang, Ying-Qiang Xiang, Xian-Bin Li, Xiao-Lan Cao, Tong Guo, Zheng-Rong Liu, Helen F K Chiu, Gabor S Ungvari, Jose de Leon
OBJECTIVE: The aim of the study was to examine published randomized controlled trials (RCTs) for the efficacy and safety of adjunctive electroconvulsive therapy (ECT) when combined with antipsychotics (APs) versus AP therapy for schizophrenia and related disorders during the acute phase. METHODS: Two evaluators independently selected studies, extracted data, and conducted quality assessment and data synthesis. Standardized and weighted mean differences (SMD/WMD), risk ratio (RR) ±95% confidence intervals (CIs), number needed to treat (NNT), and number needed to harm (NNH) were calculated...
August 3, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27424873/rocuronium-sugammadex-for-electroconvulsive-therapy-management-in-neuroleptic-malignant-syndrome-a-case-report
#8
P Casas Reza, M Gestal Vázquez, Á Outeiro Rosato, S López Álvarez, P Diéguez García
Neuroleptics are a group of drugs widely used in the treatment of psychotic symptoms. Among their adverse effects is the ability to trigger a neuroleptic malignant syndrome (NMS). The diagnosis of NMS is determined by exclusion, and its initial therapeutic management should be the withdrawal of neuroleptics, the administration of benzodiazepines, and electroconvulsive therapy (ECT). ECT is an effective treatment in these patients, and in those cases with a poor response to treatment with antipsychotic drugs...
July 14, 2016: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/27424799/structural-network-changes-in-patients-with-major-depression-and-schizophrenia-treated-with-electroconvulsive-therapy
#9
Robert Christian Wolf, Henrike Maria Nolte, Dusan Hirjak, Stefan Hofer, Ulrich Seidl, Malte Sebastian Depping, Bram Stieltjes, Klaus Maier-Hein, Fabio Sambataro, Philipp Arthur Thomann
Electroconvulsive therapy (ECT) is one of the most effective treatments in severe and treatment-resistant major depressive disorder (MDD). In schizophrenia (SZ), ECT is frequently considered in drug-resistant cases, as an augmentation of antipsychotic treatment or in cases when rapid symptom relief is indicated. Accumulating neuroimaging evidence suggests modulation of medial temporal lobe and prefrontal cortical regions in MDD by ECT. In SZ, ECT-effects on brain structure have not been systematically investigated so far...
September 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27384628/-clinical-characteristics-of-patients-treated-with-electroconvulsive-therapy-in-a-public-hospital-in-peru
#10
Carla Cortez-Vergara, Lizardo Cruzado, Ira Galia Rojas-Rojas, Miguel Sánchez-Fernández, Guillermo Ladd-Huarachi
With the purpose of describe the profile of use of electroconvulsive therapy (ECT) on hospitalized patients at "Honorio Delgado - Hideyo Noguchi" National Institute of Mental Health in Lima, Peru, the medical records of patients receiving ECT between 2001 and 2011 were reviewed. The main findings were: four hundred and nineteen ECT courses were applied to 372 patients, with a total of 5439 applications the most common diagnosis was paranoid schizophrenia (70.7%), the most common indication was resistance to treatment (80...
March 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/27356089/electroconvulsive-therapy-in-a-patient-with-chronic-catatonia-clinical-outcomes-and-cerebral-18-f-fludeoxyglucose-positron-emission-tomography-findings
#11
Giorgio Pigato, Beatrice Roiter, Diego Cecchin, Silvia Morbelli, Elena Tenconi, Alessandra Minelli, Marco Bortolomasi
Catatonia is a psychomotor syndrome that can be associated with both psychiatric diseases (mainly mood disorders, but also psychotic disorders) and medical conditions. Lorazepam (6-21 mg/day, occasionally up to 30 md/day) is the first choice treatment and electroconvulsive therapy (ECT) is the second line, regardless of the underlying clinical condition. There are some evidences also for effectiveness of other medications. Patients treated acutely usually show rapid and full therapeutic response but even longstanding catatonia can improve...
December 2016: Journal of ECT
https://www.readbyqxmd.com/read/27322602/efficacy-and-safety-of-combining-clozapine-with-electrical-or-magnetic-brain-stimulation-in-treatment-refractory-schizophrenia
#12
Shyam Sundar Arumugham, Jagadisha Thirthalli, Chittaranjan Andrade
INTRODUCTION: A substantial proportion (40-70%) of patients with treatment-resistant schizophrenia experience persistent symptoms despite an adequate clozapine trial. Brain stimulation techniques (BST) such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), and transcranial direct current stimulation (tDCS) have shown promise in medication-refractory schizophrenia. However, their co-administration with clozapine raises some safety concerns. AREAS COVERED: We conducted a systematic literature search through Pubmed and cross-references for relevant publications evaluating the safety and efficacy of combining BST with clozapine...
September 2016: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/27311104/increased-serum-brain-derived-neurotrophic-factor-levels-following-electroconvulsive-therapy-or-antipsychotic-treatment-in-patients-with-schizophrenia
#13
J Li, F Ye, W Xiao, X Tang, W Sha, X Zhang, J Wang
BACKGROUND: Many schizophrenia patients experience residual symptoms even after treatment. Electroconvulsive therapy (ECT) is often used in medication-resistant schizophrenia patients when pharmacologic interventions have failed; however, the mechanism of action is unclear. Brain-derived neurotrophic factor (BDNF) levels are reduced in drug-naive, first-episode schizophrenia and are increased by antipsychotic treatment. We tested the hypothesis that ECT increases serum BDNF levels by measuring BDNF concentrations in schizophrenia patients before and after they received ECT...
August 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/27259074/common-use-of-electroconvulsive-therapy-for-chinese-adolescent-psychiatric-patients
#14
Qing-E Zhang, Zhi-Min Wang, Sha Sha, Chee H Ng, Stephen J Seiner, Charles A Welch, Grace K I Lok, Ines H I Chow, Fei Wang, Lu Li, Yu-Tao Xiang
PURPOSE: Little is known about the use of electroconvulsive therapy (ECT) for adolescent psychiatric patients in China. This study examined the frequency of ECT and the demographic and clinical correlates of adolescent psychiatric patients hospitalized in a tertiary psychiatric hospital in China. METHODS: This was a retrospective chart review of 954 inpatients aged between 13 and 17 years treated over a period of 8 years (2007-2013). Sociodemographic and clinical data were collected from the electronic chart management system for discharged patients...
December 2016: Journal of ECT
https://www.readbyqxmd.com/read/27255726/catatonia
#15
Sebastian Walther, Werner Strik
One of the most exciting psychiatric conditions is the bizarre psychomotor syndrome called catatonia, which may present with a large number of different motor signs and even vegetative instability. Catatonia is potentially life threatening. The use of benzodiazepines and electroconvulsive therapy (ECT) has been efficient in the majority of patients. The rich clinical literature of the past has attempted to capture the nature of catatonia. But the lack of diagnostic clarity and operationalization has hampered research on catatonia for a long time...
August 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27227402/electroconvulsive-therapy-alone-for-schizophrenia-a-meta-analysis-of-randomized-single-blind-controlled-trials-retracted
#16
Wei Zheng, Ying-Qiang Xiang, Gabor S Ungvari, Chee H Ng, Helen F K Chiu, Zheng-Rong Liu, Xiao-Lan Cao, Tong Guo, Harry H X Wang, Stephen J Seiner, Yu-Tao Xiang
PURPOSE: Electroconvulsive therapy (ECT) is a common treatment in practice for schizophrenia in most developing countries. This is a meta-analysis of the efficacy and safety of ECT alone versus antipsychotic (AP) monotherapy for schizophrenia using randomized, single-blind, controlled trial (RCT) data. METHODS: Two assessors independently extracted data. Standardized and weighted mean difference (SMD/WMD), odds ratios (ORs) ± 95% confidence intervals (CIs), and number needed to harm (NNH) were calculated by Review Manager Version 5...
August 3, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27143894/medication-management-during-electroconvulsant-therapy
#17
Monica Zolezzi
Electroconvulsive therapy (ECT) has demonstrated to be highly effective and safe, even life saving for many psychiatric disorders such as major depression, bipolar disorder and schizophrenia. Most patients who require ECT are also on concurrent pharmacotherapy. As such, the objective of this article is to provide a review of the most recent literature focusing on the medications used during an ECT procedure and on the effects of concurrent psychiatric and non-psychiatric medications on the effectiveness and safety of ECT...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27052067/premedication-effect-of-dexmedetomidine-and-alfentanil-on-seizure-time-recovery-duration-and-hemodynamic-responses-in-electroconvulsive-therapy
#18
Esmail Moshiri, Hesameddin Modir, Niknam Bagheri, Abolfazl Mohammadbeigi, Hamidreza Jamilian, Babak Eshrati
INTRODUCTION: Electroconvulsive therapy (ECT) is an effective treatment for many mental disorders, especially severe and persistent depression, bipolar disorder, and schizophrenia. The aim of this study is to compare the effect of dexmedetomidine and alfentanil on agitation, satisfaction, seizure duration, and patients hemodynamic after ECT. MATERIALS AND METHODS: In a three phase crossover randomized clinical trial, 75 patients aged between 18 and 50 years and candidate for ECT were enrolled and assigned into three groups (25 patients in each group)...
April 2016: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/26983067/thinking-about-electroconvulsive-therapy-the-opinions-of-parents-of-adolescents-with-schizophrenia-spectrum-disorders
#19
Itziar Flamarique, Inmaculada Baeza, Elena de la Serna, Alexandre Pons, Miguel Bernardo, Josefina Castro-Fornieles
OBJECTIVE: To assess the experience with, knowledge of, and attitudes toward electroconvulsive therapy (ECT) among parents of adolescents with schizophrenia spectrum disorders (SSD) who have received ECT. METHODS: A self-administered questionnaire was used to assess the experience with, knowledge of, and attitudes toward ECT in a sample of parents of adolescents diagnosed with SSD. Parents of adolescents treated with ECT before the age of 18 years (ECT group; n = 19) were compared with a randomly selected group of parents of adolescents treated only with antipsychotics (No ECT group; n = 20)...
March 16, 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/26912606/altered-serum-levels-of-matrix-metalloproteinase-2-9-in-response-to-electroconvulsive-therapy-for-mood-disorders
#20
Chiyo Shibasaki, Minoru Takebayashi, Kei Itagaki, Hiromi Abe, Naoto Kajitani, Mami Okada-Tsuchioka, Shigeto Yamawaki
BACKGROUND: Inflammatory processes could underlie mood disorders. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMP) are inflammation-related molecules. The current study sought an association between mood disorders and systemic levels of MMPs and TIMPs. METHODS: Serum was obtained from patients with mood disorders (n=21) and patients with schizophrenia (n=13) scheduled to undergo electroconvulsive therapy. Serum was also obtained from healthy controls (n=40)...
September 2016: International Journal of Neuropsychopharmacology
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