keyword
MENU ▼
Read by QxMD icon Read
search

Lom

keyword
https://www.readbyqxmd.com/read/29146936/hypomethylation-of-hoxa4-promoter-is-common-in-silver-russell-syndrome-and-growth-restriction-and-associates-with-stature-in-healthy-children
#1
Mari Muurinen, Katariina Hannula-Jouppi, Lovisa E Reinius, Cilla Söderhäll, Simon Kebede Merid, Anna Bergström, Erik Melén, Göran Pershagen, Marita Lipsanen-Nyman, Dario Greco, Juha Kere
Silver-Russell syndrome (SRS) is a growth retardation syndrome in which loss of methylation on chromosome 11p15 (11p15 LOM) and maternal uniparental disomy for chromosome 7 [UPD(7)mat] explain 20-60% and 10% of the syndrome, respectively. To search for a molecular cause for the remaining SRS cases, and to find a possible common epigenetic change, we studied DNA methylation pattern of more than 450 000 CpG sites in 44 SRS patients. Common to all three SRS subgroups, we found a hypomethylated region at the promoter region of HOXA4 in 55% of the patients...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29126635/on-road-and-laboratory-emissions-of-no-no2-nh3-n2o-and-ch4-from-late-model-eu-light-utility-vehicles-comparison-of-diesel-and-cng
#2
Michal Vojtíšek-Lom, Vít Beránek, Vojtěch Klír, Petr Jindra, Martin Pechout, Tomáš Voříšek
Exhaust emissions of eight Euro 6 light duty vehicles - two station wagons and six vans - half powered by diesel fuel and half by compressed natural gas (CNG) were examined using both chassis dynamometer and on-road testing. A portable on-board FTIR analyzer was used to measure concentrations of reactive nitrogen compounds - NO, NO2 and ammonia, of CO, formaldehyde, acetaldehyde and greenhouse gases CO2, methane and N2O. Exhaust flow was inferred from engine control unit data. Total emissions per cycle were compared and found to be in good agreement with laboratory measurements of NOX, CO and CO2 during dynamometer tests...
November 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29089112/growth-and-physiological-features-of-chaetomorpha-linum-m%C3%A3-ller-k%C3%A3-tz-in-high-density-mats
#3
Carlo Sorce, Marco Persiano Leporatti, Mauro Lenzi
Seasonal changes of high density Chaetomorpha linum mats were studied in an eutrophic coastal lagoon. We measured biomass and specific growth rate and analyzed water quality, sediment labile organic matter (LOM), photosynthetic efficiency and pigments in two areas: one subjected to sediment resuspension and algal mass shuffling through specific boats and the other left undisturbed. Low disturbance enhanced algal survival under critical summer conditions, by reducing LOM and promoting growth through thalli fragmentation...
October 28, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29053487/effect-of-experimental-conditions-in-the-accommodation-response-in-myopia
#4
Carles Otero, Mikel Aldaba, Fuensanta A Vera-Diaz, Jaume Pujol
SIGNIFICANCE: The accommodative response is more affected by the type of refractive error than the method of stimulation, field of view (FOV), or stimulus depth. PURPOSE: This study aims to analyze the effect of stimulation method, stimulus depth, and FOV on the accommodation response (AR) for emmetropes (EMM), late-onset myopes (LOM), and early-onset myopes (EOM). METHODS: Monocular AR was measured in 26 young observers (n = 9 EMM, n = 8 LOM, n = 9 EOM) under 60 different viewing conditions that were the result of permuting the following factors: (1) stimulation method (free space or Badal lens viewing), (2) stimulus depth (flat or volumetric), (3) FOV (2...
October 19, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29048074/effective-method-for-fast-and-detailed-analysis-of-holographic-patterns-over-a-large-area
#5
Li Yang, Max Karlsson
An effective method is proposed that enables one to simultaneously analyze details of numerous holographic grating patterns over a large area. Unlike the conventional approaches relying on sophisticated lighting and optical systems and dark environment, only a flatbed scanner is needed. Thanks to the "rotate-scan" measurement strategy, details of the holographic grating patterns can be obtained, e.g., spatial distribution of the grating patterns, interval and orientation of the grating grooves within each grating pattern, and defects of the holographic patterns...
September 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/28988341/randomized-phase-ii-trial-comparing-axitinib-with-the-combination-of-axitinib-and-lomustine-in-patients-with-recurrent-glioblastoma
#6
J Duerinck, S Du Four, F Bouttens, C Andre, V Verschaeve, F Van Fraeyenhove, C Chaskis, N D'Haene, M Le Mercier, A Rogiers, A Michotte, I Salmon, B Neyns
Axitinib is a small molecule tyrosine kinase inhibitor with high affinity and specificity for the family of vascular endothelial growth factor receptors. It has previously demonstrated anti-tumor activity in a small cohort of patients with recurrent glioblastoma (rGB). We conducted a non-comparative randomized phase II clinical trial investigating axitinib monotherapy versus axitinib plus lomustine (LOM) in patients with rGB. Primary endpoint was 6 month progression-free survival (6mPFS). Patients who progressed on axitinib-monotherapy were allowed to cross-over...
October 7, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28950994/the-clinical-significance-of-perivalvular-pannus-in-prosthetic-mitral-valves-can-cardiac-ct-be-helpful
#7
Suyon Chang, Young Joo Suh, Kyunghwa Han, Jin Young Kim, Young Jin Kim, Byung-Chul Chang, Byoung Wook Choi
BACKGROUND: The clinical significance of pannus in the prosthetic mitral valve (MV) is not well documented. OBJECTIVES: To investigate the clinical significance of pannus on cardiac computed tomography (CT) in patients with a prosthetic MV. METHODS: A total of 130 patients with previous MV replacement who underwent cardiac CT were retrospectively included in this study. The presence of pannus, paravalvular leak (PVL) around the prosthetic MV and limitation of motion (LOM) of the MV were analyzed using CT...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28806920/specific-ion-channels-contribute-to-key-elements-of-pathology-during-secondary-degeneration-following-neurotrauma
#8
Ryan L O'Hare Doig, Wissam Chiha, Marcus K Giacci, Nathanael J Yates, Carole A Bartlett, Nicole M Smith, Stuart I Hodgetts, Alan R Harvey, Melinda Fitzgerald
BACKGROUND: Following partial injury to the central nervous system, cells beyond the initial injury site undergo secondary degeneration, exacerbating loss of neurons, compact myelin and function. Changes in Ca(2+) flux are associated with metabolic and structural changes, but it is not yet clear how flux through specific ion channels contributes to the various pathologies. Here, partial optic nerve transection in adult female rats was used to model secondary degeneration. Treatment with combinations of three ion channel inhibitors was used as a tool to investigate which elements of oxidative and structural damage related to long term functional outcomes...
August 14, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28793296/older-age-at-multiple-sclerosis-onset-is-an-independent-factor-of-poor-prognosis-a-population-based-cohort-study
#9
Francis Guillemin, Cédric Baumann, Jonathan Epstein, Philippe Kerschen, Teresa Garot, Guillaume Mathey, Marc Debouverie
BACKGROUND: Late-onset multiple sclerosis (LOMS) frequently features a primary progressive (PP) course, strongly predicting severe disability. In this population-based cohort, we estimated the prognostic role of age at multiple sclerosis (MS) onset, independent of PP course, on disability progression. METHODS: The association of age at disease onset (adult, <50 years [AOMS], vs. late, ≥50 years [LOMS]) and time to Expanded Disability Status Scale (EDSS) score 4 and 6 was estimated by Cox regression modelling...
August 10, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28775205/therapy-related-hematological-malignancies-after-peptide-receptor-radionuclide-therapy-with-177-lu-dota-octreotate-incidence-course-predicting-factors-in-patients-with-gep-nets
#10
Hendrik Bergsma, Kirsten van Lom, Mark Konijnenberg, Boen Kam, Jaap Teunissen, Wouter de Herder, Eric Krenning, Dik Kwekkeboom
Peptide Receptor Radionuclide Therapy (PRRT) may induce long-term toxicity to the bone marrow (BM). The aim of this study was to analyze persistent dysfunction of the hematopoietic system after PRRT with (177)Lu-DOTATATE in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Methods: The incidence and course of persistent hematological dysfunction (PHD) was analyzed in 274 (=GEP-NET) out of 367 patients with somatostatin receptor-positive tumors. PHD was defined as diagnosis of Myelodysplastic Syndrome (MDS), Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Myelodysplastic/Myeloproliferative neoplasms (MDS/MPN) or otherwise unexplained cytopenia (for more than 6 months)...
August 3, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28765764/focal-ablation-for-atrial-tachycardia-from-the-double-exit-of-the-marshall-bundle-inducing-atrial-fibrillation
#11
Jung Yeon Chin, Jong Woo Kim, Ki-Woon Kang
Atrial fibrillation (AF) from the ligament/vein of Marshall (LOM/VOM) has previously been described. We report the case of a 23-year-old woman with an antiarrhythmic drug-resistant AF induced by two distinct atrial tachycardias (ATs). Focal ablation of these ATs from the double-exit of the Marshall bundle using a three-dimensional map eliminated AF triggering, even though pulmonary vein electrical isolation is the cornerstone for paroxysmal AF. Such mechanisms are important as triggering factors to plan ablation for paroxysmal AF...
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28765086/spectrum-of-atrial-arrhythmias-using-the-ligament-of-marshall-in-patients-with-atrial-fibrillation
#12
Aman Chugh, Hitinder S Gurm, Kavita Krishnasamy, Mohammed Saeed, Watchara Lohawijarn, Kyle Hornsby, Ryan Cunnane, Hamid Ghanbari, Rakesh Latchamsetty, Thomas Crawford, Krit Jongnarangsin, Frank Bogun, Hakan Oral, Fred Morady
BACKGROUND: The role of the ligament of Marshall (LOM) in patients with atrial fibrillation (AF) has not been well defined. OBJECTIVE: The purpose of this study was to describe the role of the LOM in patients with AF and related arrhythmias. METHODS: Fifty-six patients (mean age 63 ± 11 years; persistent AF in 48 [86%]; ejection fraction 0.49 ± 0.13; left atrial diameter 4.7 ± 0.6 cm) with LOM-mediated arrhythmias were included. RESULTS: A LOM-pulmonary vein (PV) connection was present in 18 patients (32%) and was eliminated with radiofrequency (RF) ablation at the left lateral ridge or crux (n = 12), at the mitral annulus (n = 3), or with alcohol/ethanol (EtOH) ablation of the vein of Marshall (VOM; n = 3)...
July 29, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28761796/the-salivary-gland-salivation-stimulating-peptide-from-locusta-migratoria-lom-sg-sasp-is-not-a-typical-neuropeptide
#13
Jan A Veenstra
The salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been identified and been shown to code for a precursor consisting of a signal peptide, several copies of the peptide separated by Lys-Arg doublets and a few other peptides. These data are consistent with it being a neuropeptide. However, antiserum raised to this peptide labels the acini of the salivary glands while RT-PCR only gives positive results in the salivary gland, but not in any ganglion of the central nervous system...
2017: PeerJ
https://www.readbyqxmd.com/read/28756658/polymers-for-3d-printing-and-customized-additive-manufacturing
#14
Samuel Clark Ligon, Robert Liska, Jürgen Stampfl, Matthias Gurr, Rolf Mülhaupt
Additive manufacturing (AM) alias 3D printing translates computer-aided design (CAD) virtual 3D models into physical objects. By digital slicing of CAD, 3D scan, or tomography data, AM builds objects layer by layer without the need for molds or machining. AM enables decentralized fabrication of customized objects on demand by exploiting digital information storage and retrieval via the Internet. The ongoing transition from rapid prototyping to rapid manufacturing prompts new challenges for mechanical engineers and materials scientists alike...
August 9, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28746432/late-onset-multiple-sclerosis-concerns-in-aging-patients
#15
Claudia Beatriz de Campos Lotti, Acary Souza Bulle Oliveira, Denis Bernardi Bichuetti, Isac de Castro, Enedina Maria Lobato Oliveira
Late onset multiple sclerosis (LOMS) is when the first symptom starts after 50 years of age, representing 4.5% of multiple sclerosis (MS) patients. This study describes the clinical characteristics of patients with LOMS followed at a specialized MS center in São Paulo. Data was obtained from medical records of 742 patients with MS. The LOMS frequency was 4.18%, median age at onset was 54 years and the predominant disease course was primary progressive (64.3%). The patients reached the disability landmarks of EDSS grades 3...
July 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28725184/sevoflurane-induces-coherent-slow-delta-oscillations-in-rats
#16
Jennifer A Guidera, Norman E Taylor, Justin T Lee, Ksenia Y Vlasov, JunZhu Pei, Emily P Stephen, J Patrick Mayo, Emery N Brown, Ken Solt
Although general anesthetics are routinely administered to surgical patients to induce loss of consciousness, the mechanisms underlying anesthetic-induced unconsciousness are not fully understood. In rats, we characterized changes in the extradural EEG and intracranial local field potentials (LFPs) within the prefrontal cortex (PFC), parietal cortex (PC), and central thalamus (CT) in response to progressively higher doses of the inhaled anesthetic sevoflurane. During induction with a low dose of sevoflurane, beta/low gamma (12-40 Hz) power increased in the frontal EEG and PFC, PC and CT LFPs, and PFC-CT and PFC-PFC LFP beta/low gamma coherence increased...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/28685297/hemodynamic-effects-of-lipid-based-oxygen-microbubbles-via-rapid-intravenous-injection-in-rodents
#17
Katherine J Black, Andrew T Lock, Lindsay M Thomson, Alexis R Cole, Xiaoqi Tang, Brian D Polizzotti, John N Kheir
PURPOSE: Low oxygen levels, or hypoxemia, is a common cause of morbidity and mortality in critically ill patients. Hypoxemia is typically addressed by increasing the fraction of inspired oxygen, the use of mechanical ventilation, or more invasive measures. Recently, the injection of oxygen gas directly into the bloodstream by packaging it within lipid-based oxygen microbubbles (LOMs) has been explored. The purpose of this work is to examine the acute hemodynamic effects of intravenous injections of LOMs...
October 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28682329/unesco-geopark-stop-ruining-turkey-s-geological-heritage
#18
A M Celal Şengör, Nalan Lom
No abstract text is available yet for this article.
July 5, 2017: Nature
https://www.readbyqxmd.com/read/28666470/the-effects-of-chronic-and-acute-physical-activity-on-working-memory-performance-in-healthy-participants-a-systematic-review-with-meta-analysis-of-randomized-controlled-trials
#19
Azeem Rathore, Barbara Lom
BACKGROUND: Understanding how physical activity (PA) influences cognitive function in populations with cognitive impairments, such as dementia, is an increasingly studied topic yielding numerous published systematic reviews. In contrast, however, there appears to be less interest in examining associations between PA and cognition in cognitively healthy individuals. Therefore, the objective of this review was to evaluate and synthesize randomized controlled trial (RCT) studies that investigated the effects of both chronic and acute PA on working memory performance (WMP) in physically and cognitively healthy individuals...
June 30, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28639168/sensitivity-of-chaos-measures-in-detecting-stress-in-the-focusing-control-mechanism-of-the-short-sighted-eye
#20
Karen M Hampson, Matthew P Cufflin, Edward A H Mallen
When fixating on a stationary object, the power of the eye's lens fluctuates. Studies have suggested that changes in these so-called microfluctuations in accommodation may be a factor in the onset and progression of short-sightedness. Like many physiological signals, the fluctuations in the power of the lens exhibit chaotic behaviour. A breakdown or reduction in chaos in physiological systems indicates stress to the system or pathology. The purpose of this study was to determine whether the chaos in fluctuations of the power of the lens changes with refractive error, i...
August 2017: Bulletin of Mathematical Biology
keyword
keyword
44943
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"