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primary tracheal tumor

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https://www.readbyqxmd.com/read/29627048/pathology-of-primary-tracheobronchial-malignancies-other-than-adenoid-cystic-carcinomas
#1
REVIEW
Darroch Moores, Paresh Mane
Most primary tracheal tumors are malignant. Malignancy of larynx and bronchi are much more likely than trachea. Tracheal tumors are most likely due to direct extension for surrounding tumors. Squamous cell carcinoma and adenoid cystic carcinoma make up about two-thirds of adult primary tracheal tumors. Because of their predominantly local growth pattern, malignant salivary gland-type tumors show a better outcome than other histologic types.
May 2018: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/29575399/unique-application-of-awake-tracheoscopy-and-endobronchial-ultrasound-in-the-management-of-tracheal-mucoepidermoid-carcinoma
#2
Saad Rehman, Harold N Lovvorn, Otis B Rickman, Christopher T Wootten, Sivakumar Chinnadurai
BACKGROUND: Mucoepidermoid carcinoma of the trachea is a rare pediatric malignancy that presents unique challenges in diagnosis, operative management, and surveillance. METHODS AND RESULTS: We present a 17-year-old girl with primary tracheal mucoepidermoid carcinoma presenting in acute respiratory distress due to near-total occlusion of the tracheal airway. An algorithmic approach to preoperative planning was developed to evaluate and remove the tumor endoscopically without compromising oxygenation...
March 25, 2018: Head & Neck
https://www.readbyqxmd.com/read/29504982/extramedullary-plasmacytoma-of-the-trachea-a-case-report-and-review-of-the-literature
#3
Xi Zhang, Lei Su, Yu-Ge Ran, Shuai Qie, Xin Zhang, Chan Liu, Hong-Yun Shi
RATIONALE: Extramedullary plasmacytomas (EMPs) are rare solitary soft tissue tumors characterized by monoclonal proliferation of plasma cells. Most lesions occur in the head and neck, but primary tracheal lesions are very rare. PATIENT CONCERNS: In this report, we describe a case of tracheal EMP discovered in a 48-year-old man who presented with a history of progressive dyspnea. DIAGNOSES: Computed tomography (CT) revealed a well-defined nodular mass in the posterior wall of trachea without signs of invasion of the tracheal walls...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29501297/tracheal-paraganglioma-presenting-as-stridor-in-a-pediatric-patient-case-report-and-literature-review
#4
Amy L Dimachkieh, Allison Dobbie, Damon R Olson, Mark A Lovell, Jeremy D Prager
OBJECTIVE: To review tracheal paragangliomas and describe the clinical presentation, radiologic findings, operative management, and histologic findings of a pediatric patient who presented with stridor refractory to traditional asthma therapy. METHODS: Chart review of an 8-year-old male who presented to a tertiary care pediatric hospital and literature review of tracheal paragangliomas. RESULTS: We present the case of an 8-year-old male who presented with new-onset of wheezing and dyspnea on exertion...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29486180/primary-salivary-type-lung-cancers-in-the-national-cancer-database
#5
Benjamin J Resio, Alexander S Chiu, Jessica Hoag, Andrew P Dhanasopon, Justin D Blasberg, Daniel J Boffa
BACKGROUND: Primary Salivary Type Lung Cancers (PSTLC) such as Adenoid Cystic Carcinoma (ACC) and Mucoepidermoid Carcinoma (MEC) are uncommon primary lung tumors that given their rarity, remain incompletely understood. This study aimed to characterize the management and outcomes associated with these less common pulmonary malignancies. METHODS: Patients in the National Cancer Database (NCDB) diagnosed with primary lung and bronchial (not tracheal) MEC and ACC between 2004-2014 were identified...
February 24, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29202770/a-10-year-clinical-outcome-of-radiotherapy-as-an-adjuvant-or-definitive-treatment-for-primary-tracheal-adenoid-cystic-carcinoma
#6
Hyoung Uk Je, Si Yeol Song, Dong Kwan Kim, Yong-Hee Kim, Seong-Yun Jeong, Geum Mun Back, Wonsik Choi, Su Ssan Kim, Seung-Il Park, Eun Kyung Choi
BACKGROUND: To evaluate the role of radiotherapy (RT) as an adjuvant or definitive treatment in primary tracheal adenoid cystic carcinoma (ACC) for local tumor control and survival. METHODS: A retrospective chart review was performed in 22 patients treated with adjuvant or definitive RT for primary tracheal ACC at a single center between November 1994 and December 2008. RESULTS: Thirteen and 9 patients received adjuvant and definitive RT, respectively...
December 4, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29183345/primary-tracheal-schwannoma-a-review-of-a-rare-entity-current-understanding-of-management-and-followup
#7
Shadi Hamouri, Nathan M Novotny
BACKGROUND: Neurogenic tumors of the tracheobronchial tree are extremely rare and include neurofibroma and schwannoma. We report a case of primary recurrent tracheal schwannoma causing obstructive airway symptoms. CASE PRESENTATION: A 60-year-old man presented with obstructive airway symptoms due to recurrent tracheal schwannoma. Due the recurrence, size of the tumor and low surgical risk, the patient was treated with tracheal resection. CONCLUSION: Primary endotracheal neurogenic tumors are extremely rare, but one should consider them in the differential diagnosis of persistent upper airway symptoms...
November 28, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29124061/diagnostics-of-thyroid-malignancy-and-indications-for-surgery-in-the-elderly-and-younger-counterparts-comparison-of-3-749-patients
#8
Krzysztof Kaliszewski, Dorota Diakowska, Marta Strutyńska-Karpińska, Beata Wojtczak, Michał Aporowicz, Zdzisław Forkasiewicz, Waldemar Balcerzak, Tadeusz Łukieńczuk, Paweł Domosławski
Background: It seems valuable for clinicians to know if diagnostics of thyroid malignancy (TM) and indications for surgery in the elderly patients differ from these in younger counterparts. Materials and Methods: Retrospective analysis of the medical records of 3,749 patients surgically treated for thyroid tumor. Data of patients with histopathology confirmed TM ( n = 309) were studied. Results: The rate of cytological prediction to malignancy was more than three times higher in elderly women...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29067926/rare-tracheal-tumor-solitary-plasmacytoma
#9
R Stevic, M Ercegovac, J Stojšić, N Čolić
Primary tracheal tumors are rare and trachea is an exceedingly rare site of extramedullary plasmacytoma (EMP). We report a case of solitary tracheal plasmacytoma causing symptoms of airway obstruction in a 59-year-old man. Flow/volume loop indicated the fixed central airway obstruction. Computerized tomography and bronchoscopy demonstrated a sessile tumor on posterior tracheal wall obstructing 80% of the lumen. Partial tracheal resection with T-T anastomosis was performed. Pathologic analysis of resected mass revealed EMP...
October 23, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28969727/manual-trans-tracheal-high-frequency-positive-pressure-ventilation-for-left-main-bronchus-and-carinal-mass-surgical-resection-in-a-child
#10
Mohammad Irfan Akhtar, Faisal Junejo, Hamid Iqil Naqvi, Mohammad Hamid
Inflammatory myofibroblastic tumor (IMT), also called pseudo-tumor, is a very rare condition and accounts for less than 1% of primary lung tumor. It is most common benign tumor of lung in children. This case is reported with the objective of highlighting the role of manual trans-tracheal high frequency positive pressure ventilation (HFPPV) in facilitating surgical resection with maintenance of adequate oxygenation and a little compromised ventilation. A9-year boy, weighing 21 kg, was diagnosed as a case of IMTof left main bronchus on biopsy and was successfully treated by surgical excision through left thoracotomy...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28927948/survival-trends-in-patients-with-tracheal-carcinoma-from-1973-to-2011
#11
Surbhi Agrawal, Christopher Jackson, Karel-Bart Celie, Chetan Dodhia, Daphne Monie, Jose Monzon, Theodor Kaufman, Nicholas J Hellenthal
PURPOSE: The prognosis for primary tracheal cancer is dismal. We investigated whether there has been improvement in survival in tracheal cancer patients and how treatment modality affected overall and cancer-specific survival. MATERIALS AND METHODS: Using the Surveillance, Epidemiology, and End Results database, 1144 patients with tracheal cancer were identified between 1973 and 2011. Patients were stratified by age group, gender, race, tumor histology, and treatment modality...
August 26, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28910916/-primary-tracheal-malignant-glomus-tumor-with-lung-metastasis-diagnosed-by-pathological-analysis-a-case-report-and-literature-review
#12
B Huang, F G Chen, J Zhuang, W C Zheng, W Y Zhu, Q C Zhang, S H Wang, C M Guo, C M Xie
Objective: To study the clinical manifestations, pathological features, diagnosis, differential diagnosis, treatment and prognosis of primary tracheobronchial or pulmonary malignant glomus tumor (MGT). Methods: A case of primary tracheal MGT with lung metastasis diagnosed by pathological analysis admitted to Affiliated Shantou Hospital of Sun Yat-sen University in May. 2015 was analyzed, and the related literatures were reviewed. We searched databases including PubMed, Embase, Ovid, Cochrane, Wanfang and Chinese National Knowledge infrastructure (CNKI), using the keyword "tracheal or bronchial or pulmonary malignant glomus tumor" from Jan...
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28874619/surgical-management-of-primary-and-recurrent-carcinoma-showing-thymous-like-elements-castle
#13
Federico Attene, Ilia Patrizia Pisano, Carlo Pala, Antonio Marrosu, Corrado Bozzo, Fabrizio Scognamillo
INTRODUCTION: Carcinoma showing thymous-like elements (CASTLE) is a rare tumor with only a few cases described in the scientific literature. The aim of the present review is to analyze the data available on the therapeutic options employed in CASTLE tumors and to outline the best surgical management to adopt. MATERIALS AND METHODS: English-language articles published from 1985 through November 2016, and related to CASTLE cases were retrieved using the Pubmed database and specific key-words...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28853613/lung-endothelial-microrna-1-regulates-tumor-growth-and-angiogenesis
#14
Asawari Korde, Lei Jin, Jian-Ge Zhang, Anuradha Ramaswamy, Buqu Hu, Saeed Kolahian, Brenda Juan Guardela, Jose Herazo-Maya, Jill M Siegfried, Laura Stabile, Margaret A Pisani, Roy S Herbst, Naftali Kaminski, Jack A Elias, Jonathan T Puchalski, Shervin S Takyar
RATIONALE: Vascular endothelial growth factor down-regulates microRNA-1 (miR-1) in the lung endothelium, and endothelial cells play a critical role in tumor progression and angiogenesis. OBJECTIVES: To examine the clinical significance of miR-1 in non-small cell lung cancer (NSCLC) and its specific role in tumor endothelium. METHODS: miR-1 levels were measured by Taqman assay. Endothelial cells were isolated by magnetic sorting. We used vascular endothelial cadherin promoter to create a vascular-specific miR-1 lentiviral vector and an inducible transgenic mouse...
December 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28767607/primary-clear-cell-carcinoma-of-the-trachea-a-care-compliant-case-report
#15
Min Li, Wenye Zhu, Rana Sami Ullah Khan, Ummair Saeed, Shaoqing Shi, Zhuang Luo
RATIONALE: Primary clear cell carcinoma of the lung is a rare condition, and presentation as an endotracheal lesion is even more unusual. In this report, we present a patient with clear cell carcinoma occurring in the trachea, which obstructed the tracheal lumen and lead to the respiratory distress. PATIENT CONCERNS: A 60-year old female patient was admitted due to a 6-month history of dyspnea with worsening symptoms for 1 month. Chest CT scan revealed a smooth nodular shadow with homogeneous density on the wall of upper trachea...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28695809/diagnosis-and-clinical-analysis-of-primary-thyroid-lymphoma
#16
Yong Xie, Wenjing Liu, Yuewu Liu, Wenze Wang, Mengyi Wang, Hongfeng Liu, Xiaoyi Li, Weisheng Gao
Objective To summarize our experiences in the diagnosis and prognosis of different subtypes of primary thyroid lymphoma (PTL). Methods The clinical data of 27 PTL patients who were treated in our hospital from January 1998 to December 2014 were retrospectively analyzed. The pathological types of these patients included B cell lymphoma unclassifiable (BCLU) (n=5),mucosa-associated lymphiod tissue lymphoma (MALT) (n=9),diffuse large B cell lymphoma (DLBCL) (n=12),and T cell lymphoma (n=1). Results Of all these 27 cases,the most common clinical symptom was painless swelling of the neck (n=21,77...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28665067/the-different-clinical-aspects-of-pediatric-primary-airway-tumors-in-the-larynx-trachea-and-bronchi
#17
Hyun Ju Cho, Jisun Yoon, Eun Lee, Yoon Se Lee, Sang Yoon Kim, Jong Lyel Roh, Dong Kwan Kim, Se Hoon Choi, Seung Il Park, Yong Hee Kim, Kyung Nam Koh, Ho Joon Im, Jong Jin Seo, Soo Jong Hong, Jinho Yu
Primary airway tumors are rare in children and no literature reviewed their characteristics each location. We evaluate the clinical characteristics and outcomes of Korean children with primary airway tumors, from the larynx to bronchi. A retrospective chart review of children with primary tumors of the larynx, trachea, and bronchi at Asan Medical Center from January 2000 to July 2016 was conducted. Nineteen children were diagnosed with primary airway tumors of the larynx (47.4%), trachea (10.5%), and bronchi (42...
August 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28458792/tracheal-glomus-tumor-a-case-report-and-review-of-the-literature
#18
Ollin Venegas, Andrew Newton, Norge Vergara, Sunil Singhal, Jarrod D Predina
Glomus tumors are rare neoplasms that typically occur within the dermis or subcutis of the subungual space. Primary glomus tumors of the thorax are exceedingly uncommon, thus standard-of-care management is lacking. In this report we describe the management of a patient presenting with a symptomatic glomus tumor of the posterior trachea, and provide a comprehensive review including all documented tracheal glomus tumor reports.
March 24, 2017: Rare Tumors
https://www.readbyqxmd.com/read/28449512/primary-tracheal-schwannoma-treated-by-surgical-resection-a-case-report
#19
Ding-Pei Han, Jie Xiang, Zhi-Qiu Ye, Dan-Nong He, Xiao-Chun Fei, Chao-Fu Wang, Jia-Ming Che, Jun-Biao Hang, He-Cheng Li
The rarity and non-specific symptoms of benign primary tracheal tumors always leaded to misdiagnosis and delayed treatment, and also undefined the optimal treatment. In this case, a 45-year-old woman had a history of progressive shortness of breath and dry cough for several years, CT scan revealed an intra-luminal tracheal mass invaded the left side of tracheal wall. After being located by bronchoscope preoperatively, the tumor was removed by surgical resection. The tumor was 1.5 cm in diameter with intact capsule...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28407313/prognosis-of-primary-tracheal-tumor-a-population-based-analysis
#20
Jiaxi He, Jianfei Shen, Jun Huang, Chenyang Dai, Wenhua Liang, Minhua Ye, Min Kong, Baofu Chen, Chengchu Zhu, Jianxing He
BACKGROUND: To elucidate the survival outcomes of tracheal tumors and to propose the potential stage of tracheal tumors. METHOD: All cases of primary tracheal malignant tumors were extracted from the Surveillance, Epidemiology, and End Results database (SEER) during 1973-2013. The overall survival was calculated using Kaplan-Meier method. Cox regression was utilized to identify the prognostic factors. RESULT: A total of 287 cases were finally included...
June 2017: Journal of Surgical Oncology
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