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primary tracheal tumor

G L Serbanescu, R M Anghel
Background: Endobronchial and endotracheal metastases from extra-pulmonary solid tumors are rare. Patients and methods: We reported the case of a patient diagnosed with endobronchial and endotracheal metastases from rectal adenocarcinoma. Case report: Patient P.G., 62 years old, was diagnosed with a rectal tumor in 2011, for which, a surgical intervention was performed (pT3 pN2a M0, stage IIIB). Afterwards, she underwent adjuvant chemotherapy and concomitant radiochemotherapy. In September 2013, the chest CT showed 2 nodules for which, an incomplete surgical resection was done and which were histopathologically diagnosed as metastases from rectal cancer...
January 2017: Journal of Medicine and Life
Jin Soo Andy Song, S Mark Taylor, Jonathan Trites, Matthew H Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon, Robert D Hart
BACKGROUND: Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8-3.8% for papillary and 6-20% for follicular variants of well-differentiated thyroid cancers (WDTCs). In rare instances, tumor-to-tumor metastasis between two true primary neoplasms can occurs. This medical phenomenon has previously occurred as a clear cell renal cell carcinoma (CCRCC) spreading to a WDTC...
March 1, 2017: Journal of Otolaryngology—Head & Neck Surgery
Maria Manuel Costa, Sandra Belo, João Capela-Costa, Jennifer Costa, Davide Carvalho
Thyroid metastases are rare in clinical practice. We describe the case of an 85-year-old woman who was referred to our department due to a multinodular goiter with compressive symptoms and subclinical hyperthyroidism. The patient was also undergoing evaluation for a polyp in her left nasal cavity, which was then diagnosed as a malignant melanoma of the nasal mucosa. A thoracoabdominal magnetic resonance imaging obtained for cancer staging revealed a > 50% tracheal obstruction caused by the goiter. The patient underwent simultaneous total thyroidectomy and melanoma excision...
February 16, 2017: Archives of Endocrinology and Metabolism
Patricio Varela, Luca Pio, Elisa Brandigi, Irene Paraboschi, Nazhia Khen-Dunlop, Erik Hervieux, Cecile Muller, Girolamo Mattioli, Sabine Sarnacki, Michele Torre
Although primary tracheobronchial tumors are extremely rare in children, recurrent respiratory symptoms resistant to conventional therapy require further investigations to exclude possible malignant obstructive causes. As the matter of fact, early diagnosis may allow minimally invasive surgeries, improving the standard of living and the globally survival rate. The aim of this article is to provide an overview of diagnosis and management of tracheobronchial tumors in the early age, since only few reports are reported in the worldwide literature...
December 2016: Journal of Thoracic Disease
Chien-Heng Lin, Yu-Hua Chao, Kang-Hsi Wu, Wei-Ching Lin
BACKGROUND: Asthma is a very common disease, but primary tracheal tumors are extremely rare in children. Wheezing is not pathognomonic, but is the typical presentation of asthma and could also be found in patients with tracheal tumors. CLINICAL FINDINGS: This report describes a 12-year-old boy with a previous history of frequent asthma attacks and experienced responses to antiasthma treatment. He was admitted to the hospital due to persistent wheezing and progressive dyspnea...
November 2016: Medicine (Baltimore)
Eri Hagiwara, Yasuhiro Gon, Kentaro Hayashi, Mai Takahashi, Yuko Iida, Hisato Hiranuma, Yoshiko Nakagawa, Tsukasa Hataoka, Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Noriaki Takahashi, Shu Hashimoto
The case subject was a 58-year-old woman who presented to our hospital with a chief complaint of respiratory discomfort. Wheezing could be heard in both lungs; treatment was initiated with inhaled steroids for suspected bronchial asthma. However, 1 week later, the respiratory discomfort had not improved and the wheezing sound had progressed to the neck area. Upper airway obstruction was suspected; therefore, chest computed tomography (CT) was performed, revealing tracheal stenosis caused by a tumor in the upper airway...
August 2016: Journal of Thoracic Disease
Jeong-Hwa Kwon, Se Jin Jang, Joon Seon Song, Seung-Ho Choi, Kyung-Ja Cho
Primary tracheal adenocarcinomas are rare. Here, we report on the liquid-based sputum cytology of a bicomponent mucin-producing tracheal adenocarcinoma with histologic and immunohistochemical comparison. A 72-year-old man presented with dyspnea. Computed tomography revealed a lobulated mass in the mid-trachea. Sputum cytology showed clusters of atypical cuboidal cells that have pleomorphic and hyperchromatic nuclei and intracytoplasmic mucin. There were additional bland-looking components of regular clusters of cuboidal epithelial cells...
December 2016: Diagnostic Cytopathology
Juan P Gurria, David M De Acosta, Niloufar Hafezi, Eman B Yousif, Ehab AlAmeer, Richard C Anderson
BACKGROUND: Primary malignant tracheal tumors are rare, accounting for approximately 0.2 % of respiratory tract tumors yearly, with squamous cell carcinomas and adenoid cystic carcinomas accounting for two-thirds of these cases. Sarcomatoid carcinomas are a group of poorly differentiated non-small cell lung carcinomas containing a component of sarcoma or sarcoma-like (spindle and/or giant cell) differentiation, categorized into five morphologic subgroups. Spindle cell sarcomatoid carcinoma is a rare variant of sarcomatoid carcinomas, consisting of only spindle-shaped tumor cells...
August 5, 2016: Journal of Cardiothoracic Surgery
Marco Andolfi, Maurizio Vaccarili, Roberto Crisci, Francesco Puma
BACKGROUND: Primary malignant tracheal tumors account for only 0.2 % of all malignancies of the respiratory tract. Tracheal chondrosarcoma is a rare condition and only 17 cases have been described in the literature from 1965 to date. Herein we report the very unusual case of a patient with a tracheal chondrosarcoma, electively treated by curative surgery despite the virtually complete obstruction of the airway. CASE PRESENTATION: We present the case of a 79-year old Caucasian man with long-lasting wheezing misdiagnosed as asthma and affected by a tracheal chondrosarcoma almost completely obstructing the airway...
July 11, 2016: Journal of Cardiothoracic Surgery
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
Patricio Varela, Luca Pio, Michele Torre
Primary tracheobronchial tumors are rare lesions that can be benign or malignant, with different location along the airway tree. Symptoms may include wheezing, chronic pneumonia, asthma, chest pain, recurrent cough, atelectasis, haemoptysis, and weight loss. Due to the heterogeneity of symptoms, diagnosis can be difficult and the airway involvement can lead progressively to a bronchial or tracheal obstruction. Due to the rarity of primary tracheobronchial tumors in children, there are not any oncological guidelines on pre-operative work-up, treatment, and follow-up...
June 2016: Seminars in Pediatric Surgery
Tomoo Yuba, Yoshinori Yamashita, Hiroaki Harada, Norifumi Tsubokawa, Hideki Nagata, Taiichi Takasaki, Shigeaki Kurita, Kiyoshi Fujii
We report a case of tracheal resection and primary anastomosis for adenoid cystic carcinoma using an extracorporeal membrane oxygenation (ECMO). A 45-year-old female was referred to our hospital because of a tracheal tumor that occupied most of the tracheal lumen. In case of airway obstruction by the tracheal tumor during anesthesia and operation, we decided to use ECMO before induction of general anesthesia. Under secure respiratory control using ECMO, tracheal resection and primary anastomosis was performed...
June 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Soo Yoon Moon, Hee Su Park, Ji Young Woo, Jae Kyun Choi, HaeMi Oh, Kyung Up Kim, Young Soo Rho, Eun-Jae Chung, SeongJin Cho, Yousang Ko, So Young Park, Eun-Kyung Mo, Yong Bum Park
A 48-year-old woman was referred to our clinic because she had been experiencing hemoptysis for 1 month. Chest computed tomography revealed a small portion of a thyroid mass was penetrating the trachea. Bronchoscopy revealed a blood vessel covered mass located in her trachea. The presence of a malignant tumor was confirmed by a biopsy. The patient was referred to the otolaryngology department for tumor resection and a pathological evaluation identified the thyroid angiosarcoma with tracheal invasion. Angiosarcomas have a poor prognosis, but the patient has not experienced any recurrence two years after surgery...
2016: Internal Medicine
Seijiro Sato, Akihiko Kitahara, Terumoto Koike, Takehisa Hashimoto, Riuko Ohashi, Noriko Motoi, Masanori Tsuchida
INTRODUCTION: Parathyroid adenomas are the most common cause of primary hyperparathyroidism. However, cases of parathyroid adenomas greater than 4cm with osteitis fibrosa cystica are extremely rare. Herein, we report a case of resection of a large ectopic mediastinal parathyroid adenoma. CASE PRESENTATIONS: A 46-year-old female with chief complaints of bone pain and gait disturbance was referred to our hospital. Physical examination revealed many mobile teeth in her oral cavity, distortion of the vertebral body, and bowlegs...
2016: International Journal of Surgery Case Reports
Divya Gupta, Ishwar Singh, Pirabu Sakthivel
Primary tumors of the trachea, which may be benign or malignant, account for fewer than 0.1 % of tumors. Adenoid cystic carcinoma is the second most common tracheal tumor. It poses a diagnostic and therapeutic challenge because of its slow growth and tendency for local recurrence and late metastasis. We present a case of adenoid cystic carcinoma of trachea which was misdiagnosed and mistreated as asthma initially because of its inherent indolent progression. It is important to be acquainted with this condition to prevent delay in diagnosis and provide timely treatment...
March 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
Si-Yun Wang, Shu-Xia Wang, Ji-Qin Liao, Gang Chen
PURPOSE: Primary malignant tracheal tumors are rare, and their clinical presentation often resembles other diseases of the respiratory system. This study summarized F-FDG PET/CT and CE-CT findings on histologically confirmed primary malignant tracheal tumors in 13 patients. MATERIALS AND METHODS: We retrospectively reviewed the F-FDG PET/CT and CE-CT findings of 13 patients with histologically confirmed primary tumors who had undergone PET/CT and CE-CT in the same session...
August 2016: Clinical Nuclear Medicine
Satoshi Ideno, Atsushi Shinto, Taku Matsuoka, Noriko Miyazawa, Shinichi Yamamoto
Tracheoinnominate artery fistula (TIF) is a relatively rare life-threating complication of long-term tracheostomy. Two patients with TIF were successfully resuscitated by extracorporeal membrane oxygenation (ECMO) support along with advanced cardiovascular life support. The first patient was a 16-year-old boy undergoing long-term tracheostomy because of cerebral palsy, and the other patient was a previously healthy 11-year-old girl who had undergone primary tracheal tumor resection. In both cases, the onset of TIF was sudden, and the patients were immediately transferred to the operating room for emergency thoracotomy under ongoing cardiopulmonary resuscitation...
February 2016: Masui. the Japanese Journal of Anesthesiology
Wan-Ting Hung, Hsao-Hsun Hsu, Ming-Hui Hung, Pei-Yin Hsieh, Ya-Jung Cheng, Jin-Shing Chen
BACKGROUND: Sporadic case reports have shown that wedge resection and lobectomy can be performed via nonintubated video-assisted thoracoscopic surgery (VATS) with a single incision. We report the feasibility and safety of nonintubated uniportal VATS for resection of various lung lesions. METHODS: From January 2014 to June 2015, we retrospectively reviewed the records of 116 consecutive patients who underwent nonintubated uniportal VATS for diagnosis or treatment of lung lesions...
March 2016: Journal of Thoracic Disease
E V Levchenko, S M Ergnyan, V A Shutov, A S Barchuk
AIM: To evaluate results of circular resection and carina reconstruction in patients with bronchial cancer. MATERIAL AND METHODS: Study included 82 patients with bronchial malignant tumors operated for the period from 1998 to 2014. Mean age was 56±1.1 years (range 24-75). There were 75 men and 7 women. Squamous cell carcinoma, adenocarcinoma, dimorphic cancer, carcinoid, adenocystic cancer, small cell cancer and clear cell renal cancer were observed in 66, 9, 1, 3, 1, 1 and 1 patients respectively...
2016: Khirurgiia
Yining He, Zhiwen Xie, Jinglong Dai, Yanjie Cao, Jinlian Hou, Yansheng Zheng, Tianchao Wei, Meilan Mo, Ping Wei
Avian infectious bronchitis virus (IBV) is a Gammacoronavirus in the family Coronaviridae and causes highly contagious respiratory disease in chickens. Innate immunity plays significant roles in host defense against IBV. Here, we explored the interaction between IBV and the host innate immune system. Severe histopathological lesions were observed in the tracheal mucosa at 3-5 days post inoculation (dpi) and in the kidney at 8 dpi, with heavy viral loads at 1-11 and 1-28 dpi, respectively. The expression of mRNAs encoding Toll-like receptor (TLR) 3 and TLR7 were upregulated at 3-8 dpi, and that of TIR-domain-containing adapter-inducing interferon (IFN) β (TRIF) was upregulated at 21 dpi in the trachea and kidney...
February 2016: Virologica Sinica
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