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Vertical bone augmentation

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https://www.readbyqxmd.com/read/29346436/bone-marrow-concentrate-promotes-bone-regeneration-with-a-suboptimal-dose-of-rhbmp-2
#1
Kazuhiro Egashira, Yoshinori Sumita, Weijian Zhong, Takashi I, Seigo Ohba, Kazuhiro Nagai, Izumi Asahina
Bone marrow concentrate (BMC), which is enriched in mononuclear cells (MNCs) and platelets, has recently attracted the attention of clinicians as a new optional means for bone engineering. We previously reported that the osteoinductive effect of bone morphogenetic protein-2 (BMP-2) could be enhanced synergistically by co-transplantation of peripheral blood (PB)-derived platelet-rich plasma (PRP). This study aims to investigate whether BMC can effectively promote bone formation induced by low-dose BMP-2, thereby reducing the undesirable side-effects of BMP-2, compared to PRP...
2018: PloS One
https://www.readbyqxmd.com/read/29340348/peri-implant-tissues-and-patient-satisfaction-after-treatment-of-vertically-augmented-atrophic-posterior-mandibles-with-intraoral-onlay-block-bone-grafts-a-retrospective-3-year-case-series-follow-up-study
#2
Amparo Aloy-Prósper, David Peñarrocha-Oltra, Maria Peñarrocha-Diago, Federico Hernández-Alfaro, Miguel Peñarrocha-Diago
PURPOSE: To evaluate the peri-implant soft and hard tissues of dental implants placed in vertically regenerated posterior mandibles with intraoral onlay block bone grafts and patient satisfaction at 3-year follow-up. MATERIALS AND METHODS: A retrospective study of patients with dental implants placed in posterior mandibular sites vertically augmented with intraoral onlay block bone grafts was carried out between 2005 and 2009 at the University of Valencia. The outcomes assessed at the 3-year follow-up visit were the peri-implant soft tissues (Plaque Index and Bleeding Index, probing depth, keratinized mucosa width, and recession), implant survival and success rates, marginal bone loss, and patient satisfaction...
January 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29336105/senescence-chips-for-ultrahigh-throughput-isolation-and-removal-of-senescent-cells
#3
Yuchao Chen, Pan Mao, Antoine M Snijders, Daojing Wang
Cellular senescence plays an important role in organismal aging and age-related diseases. However, it is challenging to isolate low numbers of senescent cells from small volumes of biofluids for downstream analysis. Furthermore, there is no technology that could selectively remove senescent cells in a high-throughput manner. In this work, we developed a novel microfluidic chip platform, termed senescence chip, for ultrahigh-throughput isolation and removal of senescent cells. The core component of our senescence chip is a slanted and tunable 3D micropillar array with a variety of shutters in the vertical direction for rapid cell sieving, taking advantage of the characteristic cell size increase during cellular senescence...
January 16, 2018: Aging Cell
https://www.readbyqxmd.com/read/29316231/osteogenic-cellular-activity-around-onlaid-octacalcium-phosphate-gelatin-composite-onto-rat-calvaria
#4
Ryosuke Iwama, Takahisa Anada, Yukari Shiwaku, Kaori Tsuchiya, Tetsu Takahashi, Osamu Suzuki
The activity and the distribution of osteogenic cells around octacalcium phosphate (OCP) granules combined with gelatin matrix (OCP/Gel) onlaid on rat calvaria were analyzed histomorphometrically and immunohistochemically during vertical bone augmentation under mechanical or non-mechanical environment until 8 weeks. OCP/Gel disk was placed in subperiosteal pocket on the calvaria with or without polytetrafluoroethylene (PTFE) support. The latter is a non-mechanical stress model to alleviate the mechanical stress from the subcutaneous tissues...
January 9, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29314144/bone-augmentation-followed-by-implant-surgery-in-the-edentulous-mandible-a-systematic-review
#5
REVIEW
R J de Groot, M A E M Oomens, T Forouzanfar, E A J M Schulten
INTRODUCTION: Long-standing loss of natural teeth in the mandible can lead to severe jaw atrophy and even mandibular fracture. There is no consensus on the best preprosthetic surgical treatment to reconstruct the atrophic edentulous mandible. The purpose of this review is to provide an overview of the existing literature and to give an evidence-based recommendation for bone grafting and future research. MATERIALS AND METHODS: This systematic review was conducted according to the PRISMA statement...
January 4, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29303418/prosthetically-cad-cam-guided-bone-augmentation-of-atrophic-jaws-using-customized-titanium-mesh-preliminary-results-of-an-open-prospective-study
#6
Leonardo Ciocca, Giuseppe Lizio, Paolo Baldissara, Alessandro Sambuco, Roberto Scotti, Giuseppe Corinadesi
This study evaluated the outcomes of CAD-CAM customized titanium mesh used for prosthetically guided bone augmentation related to the occlusion driven implant position; to the vertical bone volume gain of mandible and maxilla; and to complications, like mesh exposure.. Nine patients scheduled for bone augmentation of atrophic sites were treated with custom titanium mesh and particulate bone grafts with autologous bone and anorganic bovine bone in a 1:1 ratio prior to implant surgery. The bone volume needed to augment was virtually projected based on implants position, width and length, and the mesh design was programmed for the necessary retaining screws...
January 5, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29283207/hard-tissue-volume-stability-of-guided-bone-regeneration-during-the-healing-stage-in-the-anterior-maxilla-a-clinical-and-radiographic-study
#7
Xi Jiang, Yu Zhang, Ping Di, Ye Lin
BACKGROUND: Guided bone regeneration (GBR) is currently the most widely used technique to reconstruct localized peri-implant bone defects. OBJECTIVES: To evaluate hard tissue volume stability during the healing stage of GBR with particulate bone graft and resorbable collagen membrane. MATERIALS AND METHODS: Twenty-eight patients who were missing a single maxillary incisor and required implant placement combined with GBR were randomly assigned to 2 groups: submerged (n = 14) and transmucosal (n = 14) healing groups...
December 28, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29278372/influence-of-chromium-cobalt-molybdenum-alloy-astm-f75-on-bone-ingrowth-in-an-experimental-animal-model
#8
Jésica Zuchuat, Marcelo Berli, Ysaí Maldonado, Oscar Decco
Cr-Co-Mo (ASTM F75) alloy has been used in the medical environment, but its use as a rigid barrier membrane for supporting bone augmentation therapies has not been extensively investigated. In the present study, Cr-Co-Mo membranes of different heights were placed in New Zealand white, male rabbit tibiae to assess the quality and volume of new bone formation, without the use of additional factors. Animals were euthanized at 20, 30, 40, and 60 days. Bone formation was observed in all of the cases, although the tibiae implanted with the standard membranes reached an augmentation of bone volume that agreed with the density values over the timecourse...
December 26, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29274310/is-bone-morphogenetic-protein-2-as-effective-as-alveolar-distraction-osteogenesis-for-vertical-bone-regeneration
#9
Jose M Reuss, Joan Pi-Anfruns, Peter K Moy
PURPOSE: The aim of this study was to assess the clinical effectiveness of alveolar distraction osteogenesis (ADO) versus recombinant human bone morphogenetic protein-2 (rh-BMP-2) for vertical ridge augmentation. Few data have been published on vertical bone regeneration using rh-BMP-2. MATERIALS AND METHODS: The authors implemented a retrospective cohort study and enrolled a sample composed of patients with deficient alveolar vertical bone height. The primary predictor variable was vertical augmentation with BMP-2 and a titanium mesh or ADO...
November 29, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29250831/injectable-simvastatin-gel-for-minimally-invasive-periosteal-distraction-in-vitro-and-in-vivo-studies-in-rat
#10
Jia Hao, Joshua Chou, Shinji Kuroda, Makoto Otsuka, Shohei Kasugai, Niklaus P Lang
OBJECTIVES: To evaluate whether the subperiosteal injection of simvastatin (SIM) with a novel in situ gel-forming system, SrHA/Alg (strontium hydroxyapatite/alginate), can stimulate vertical bone augmentation in a rat calvarial model. MATERIAL AND METHODS: The SrHA/Alg solution was synthesized and combined with different doses of SIM (0.01, 0.02, 0.1, and 0.2 mg) to form the following groups: (1) SrHA/Alg only, (2) SrHA/Alg/0.01, (3) SrHA/Alg/0.02, (4) SrHA/Alg/0...
December 18, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29240202/effectiveness-of-two-different-lingual-flap-advancing-techniques-for-vertical-bone-augmentation-in-the-posterior-mandible-a-comparative-split-mouth-cadaver-study
#11
Istvan Urban, Hannes Traxler, Miguel Romero-Bustillos, Sandor Farkasdi, Barry Bartee, Gabor Baksa, Gustavo Avila-Ortiz
Vertical ridge augmentation in the posterior mandible is a technique-sensitive procedure that requires adequate anatomical knowledge and precise surgical skills to minimize the risk of complications. One of the most important but also challenging aspects of the surgical technique is proper flap management to allow for passive flap closure and reduce the chances of postoperative complications affecting deep anatomical spaces. This article presents a detailed description of a novel lingual flap advancement technique and its validation via a split-mouth, comparative study using a cadaver model...
January 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29235158/single-staged-implant-placement-using-bone-ring-technique-with-and-without-membrane-placement-an-experimental-study-in-the-beagle-dog
#12
Maiko Haga-Tsujimura, Ken Nakahara, Eizaburo Kobayashi, Kensuke Igarashi, Benoit Schaller, Nikola Saulacic
AIM: To evaluate the impact of a collagen membrane on bone remodeling and osseointegration of implants placed simultaneously with a bone ring technique. MATERIAL AND METHODS: Standardized, vertical alveolar bone defects in the mandibles of six dogs were created. Tapered dental implants designed for two-stage subcrestal placement were inserted simultaneously with a bone ring technique. On one side of the mandible, the augmented sites were covered with a collagenous membrane...
December 12, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29231263/a-prospective-controlled-trial-comparing-xenograft-autogenous-bone-and-collagen-stabilized-xenograft-for-maxillary-sinus-augmentation-complications-patient-reported-outcomes-and-volumetric-analysis
#13
Jamil Alayan, Saso Ivanovski
OBJECTIVE: Compare maxillary sinus augmentation (MSA) using two different materials-anorganic bovine bone mineral (ABBM) + autogenous bone (AB) (control group) vs. collagen-stabilized ABBM (test group) in terms of complications, patient-reported outcome measures (PROMs) and volumetric analysis. MATERIALS AND METHODS: Sixty patients underwent sinus augmentation (30 control + 30 test group). Intra- and postoperative complications were recorded. PROMs measured the impact of grafting on daily activities, pain and morbidity...
December 12, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29208786/evaluation-of-short-and-regular-implants-after-prosthesis-placement-in-the-mandible-a-nonrandomized-controlled-clinical-trial
#14
Rafael S de Molon, Frederico S Lages, Carolina P Rivera, Ana P de Souza Faloni, Rogerio Margonar, Thallita P Queiroz
AIM: The aim of this nonrandomized controlled preliminary clinical trial was to compare treatment using short and conventional implants in the posterior region of the mandible after prosthesis installation by means of clinical, resonance frequency, and radiographic analyses. MATERIALS AND METHODS: A total of 10 patients with 40 dental implants already installed were included in this study. Four implants were installed for each subject, in which the length of the implants (short and conventional) was distributed according to the reminiscent alveolar bone in the left and right side of the mandible...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29194937/age-related-new-bone-formation-following-the-use-of-cancellous-bone-block-allografts-for-reconstruction-of-atrophic-alveolar-ridges
#15
Joseph Nissan, Roni Kolerman, Liat Chaushu, Marilena Vered, Sarit Naishlos, Gavriel Chaushu
BACKGROUND: An age-related decrease in the number of osteogenic progenitor cells may compromise bone augmentation. PURPOSE: Histomorphometrical assessment of age-related new bone formation, following atrophic alveolar ridge reconstruction, using cancellous bone-block allografts. MATERIAL AND METHODS: Ninety-three consecutive patients (58 females and 35 males) were referred for implant-supported restoration of 122 severe atrophic alveolar ridges...
December 1, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29174105/clinical-outcomes-of-dental-implants-after-use-of-tenting-for-bony-augmentation-a-systematic-review
#16
REVIEW
F Pourdanesh, M Esmaeelinejad, F Aghdashi
The reconstruction of severely atrophic ridges is often challenging and complicated. We searched the Medline, Embase, and Cochrane databases for articles up to October 2015 that reported the success of all types of tenting for bony regeneration. We extracted data on the size and site of the defect, the number of patients, vertical and horizontal augmentation, survival of dental implants, and complications. Thirteen studies were included, which yielded data on 423 patients with 1111 dental implants. Follow-up periods were more than five years, severely resorbed mandibles were augmented vertically by up to 10mm, and the survival rate of the implants was over 97%...
December 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29142655/maxillary-sinus-floor-augmentation-a-review-of-selected-treatment-modalities
#17
REVIEW
Thomas Starch-Jensen, Janek Dalsgaard Jensen
Objectives: The objective of the present study is to present the current best evidence for enhancement of the vertical alveolar bone height and oral rehabilitation of the atrophic posterior maxilla with dental implants and propose some evidence-based treatment guidelines. Material and Methods: A comprehensive review of the English literature including MEDLINE (PubMed), Embase and Cochrane Library search was conducted assessing the final implant treatment outcome after oral rehabilitation of the atrophic posterior maxilla with dental implants...
July 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29135351/human-studies-of-vertical-and-horizontal-alveolar-ridge-augmentation-comparing-different-types-of-bone-graft-materials-a-systematic-review
#18
Suraj Chavda, Liran Levin
Alveolar ridge augmentation can be completed with various types of bone augmentation materials (autogenous, allograft, xenograft & alloplast). Currently autogenous bone is labelled as the "gold standard" due to faster healing times and integration between native and foreign bone. No systematic review has currently determined whether there is a difference of implant success between various bone augmentation materials. The purpose of this paper was to systematically review comparative human studies of vertical and horizontal alveolar ridge augmentation comparing different types of bone graft materials (autogenous, allograft, xenograft & alloplast)...
November 14, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29120889/bone-resorption-during-submerged-healing-after-guided-bone-regeneration-a-prospective-case-series
#19
Yong Hur, Yumi Ogata, Douglas W Kim, Charles M Pham, Tae-Ho Yoon, Hirokazu Ogata
OBJECTIVE: The aim of this study was to evaluate bone resorption quantitatively during the healing period subsequent to ridge augmentation. MATERIALS AND METHODS: Sixteen patients requiring vertical ridge augmentation before implant placement were recruited in the study. The study used an allograft and nonresorbable membrane. A custom acrylic stent was used to measure changes in bone volume. Augmented bone was compared with remaining bone 6 months after guided bone regeneration (α = 0...
December 2017: Implant Dentistry
https://www.readbyqxmd.com/read/29073362/effectiveness-of-contour-augmentation-with-guided-bone-regeneration-10-year-results
#20
V Chappuis, L Rahman, R Buser, S F M Janner, U C Belser, D Buser
In aesthetic sites, the integrity of the facial bone wall dimension in the anterior maxilla is jeopardized by physiologic and structural changes postextraction. An effective regenerative protocol is key to reestablish and maintain the hard and soft tissue dimensions over time. The present prospective case series study examined the effectiveness of early implant placement with simultaneous contour augmentation through guided bone regeneration with a 2-layer composite graft in postextraction single-tooth sites over an observation period of 10 y among 20 patients...
October 1, 2017: Journal of Dental Research
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