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https://www.readbyqxmd.com/read/28324215/surgical-treatment-of-osteoporotic-thoraco-lumbar-compressive-fractures-the-use-of-pedicle-screw-with-augmentation-pmma
#1
Massimo Girardo, P Cinnella, G Gargiulo, P Viglierchio, A Rava, S Aleotti
INTRODUCTION: The osteoporosis prevalence in population is age related. The aim of this single-center observational study was evaluate the middle- to long-term performance of cement (PMMA) augmented fenestrated pedicle screws in elderly patients with thoraco-lumbar compressive fractures by osteoporosis. MATERIALS AND METHODS: From 2011 to 2015 we treated 52 patients (20 males and 32 females) suffering from somatic osteoporotic fractures (T10-L2). The average age was 73...
March 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28324104/vasoprotective-activities-of-the-adrenomedullin-ramp2-system-in-endothelial-cells
#2
Xian Xian, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Megumu Tanaka, Teruhide Koyama, Hisaka Kawate, Lei Yang, Tian Liu, Akira Imai, Liuyu Zhai, Kazutaka Hirabayashi, Kun Dai, Keiya Tanimura, Teng Liu, Nanqi Cui, Kyoko Igarashi, Akihiro Yamauchi, Takayuki Shindo
Neointimal hyperplasia is the primary lesion underlying atherosclerosis and restenosis after coronary intervention. We previously described the essential angiogenic function of the adrenomedullin (AM)-receptor activity-modifying protein 2 (RAMP2) system. In the present study, we assessed the vasoprotective actions of the endogenous AM-RAMP2 system using a wire-induced vascular injury model. We found that neointima formation and vascular smooth muscle cell proliferation were enhanced in RAMP2+/- male mice. The injured vessels from RAMP2+/- mice showed greater macrophage infiltration, inflammatory cytokine expression and oxidative stress than vessels from wild-type mice, and less re-endothelialization...
January 27, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323708/fenestrated-screws-augmented-with-pmma-increase-the-pullout-strength-of-sacral-pedicle-screws
#3
Matthew Colman, Jonathan Pond, Kent Bachus, Brandon D Lawrence, William R Spiker, Darrel S Brodke
STUDY DESIGN: Biomechanics. OBJECTIVE: The objective of this study was to compare the fixation in osteoporotic specimens of a bicortical sacral pedicle screw to the following constructs: a unicortical solid screw augmented with polymethylmethacrylate (PMMA) (TRACT), a unicortical fenestrated screw augmented with PMMA (FEN), and a bicortical screw/sacral alar screw combination (PED/ALA). SUMMARY OF BACKGROUND DATA: Rigid posterior sacral fixation of osteoporotic spines is problematic due to poor bone quality...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323702/effect-of-an-outer-sleeve-on-an-inflatable-balloon-tamp-in-terms-of-height-restoration-under-simulated-physiological-load
#4
Walter C Peppelman, William Beutler, Michael Gordon, Suresh R Chintakunta, Damien O'Halloran, Brandon Bucklen
STUDY DESIGN: An in vitro biomechanical study. OBJECTIVE: The aim of this study was to determine the effect of an optional sleeve on height restoration and compare it with the fracture reduction achieved by a commercially available inflatable bone tamp under simulated physiological load (110 N). SUMMARY OF BACKGROUND DATA: Loss of reduction after bone tamp deflation before cement injection still remains a concern. The optional sleeve surrounds the bone tamp to help maintain height during the kyphoplasty procedure while filling the created cavity with bone cement on the contralateral side...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28318949/wing-augmentation-reduces-femoral-head-cutting-out-of-dynamic-hip-screw
#5
Chih-Yu Chen, Shu-Wei Huang, Jui-Sheng Sun, Shin-Yiing Lin, Chih-Sheng Yu, Hsu-Pin Pan, Ping-Hung Lin, Fan-Chun Hsieh, Yang-Hwei Tsuang, Feng-Huei Lin, Rong-Sen Yang, Cheng-Kung Cheng
The dynamic hip screw (DHS) is commonly used in the treatment of femoral intertrochanteric fracture with high satisfactory results. However, post-operative failure does occur and result in poor prognosis. The most common failure is femoral head varus collapse, followed by lag screw cut-out through the femoral head. In this study, a novel-designed DHS with two supplemental horizontal blades was used to improve the fixation stability. In this study, nine convention DHS and 9 Orthopaedic Device Research Center (ODRC) DHSs were tested in this study...
March 17, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28301385/histological-and-histomorphometrical-determination-of-the-biogradation-of-%C3%AE-tricalcium-phosphate-granules-in-maxillary-sinus-floor-augmentation-a-prospective-observational-study
#6
Tsuneji Okada, Toru Kanai, Noriko Tachikawa, Motohiro Munakata, Shohei Kasugai
INTRODUCTION: We have recently used highly pure β-TCP (beta-tricalcium phosphate) as the bone grafting material to avoid highly invasive autogenous bone grafting. We evaluated the osseoconduction potential of highly pure β-TCP in sinus augmentation surgery treatment. MATERIALS AND METHODS: The study group comprised 13 patients who underwent maxillary sinus floor augmentation with β-TCP alone. Seven patients underwent sinus augmentation and implant placement simultaneously...
April 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28299254/volumetric-analysis-of-bone-substitute-material-performance-within-the-human-sinus-cavity-of-former-head-and-neck-cancer-patients-a-prospective-randomized-clinical-trial
#7
Jonas Lorenz, Kathrin Eichler, Mike Barbeck, Henriette Lerner, Stefan Stübinger, Catherine Seipel, Thomas J Vogl, Adorján F Kovács, Shahram Ghanaati, Robert A Sader
BACKGROUND: In numerous animal and human studies, it could be detected that in bone augmentation procedures, material's physicochemical characteristics can influence the cellular inflammatory pattern and therefore the integration in the host tissue. Histological, histomorphometrical, and clinical analyses of the integration of the biomaterial in the surrounding tissue are well established methodologies; however, they do not make a statement on volume and density changes of the augmented biomaterial...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28299252/secondary-closure-of-alveolar-cleft-with-resorbable-collagen-membrane-and-a-combination-of-intraoral-autogenous-bone-graft-and-deproteinized-anorganic-bovine-bone
#8
Lobna Abdel Aziz Aly, Nelly Hammouda
OBJECTS: Secondary alveolar bone grafting is a method that enables an excellent oral rehabilitation of the patients having alveolar cleft. The aim of this work is to report the closure of the alveolar cleft with the use of harvested autogenous bone graft combined with deproteinized anorganic bovine bone (Bio-Oss) under local anesthesia. SETTINGS AND SAMPLE POPULATION: Nine patients with age range, 8-11 years were consulted for their unilateral alveolar cleft. MATERIALS AND METHODS: A combination of symphyseal bone and deproteinized bovine bone mineral (DBBM) was placed into the alveolar cleft defect...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28298833/minimally-invasive-maxillary-sinus-elevation-using-balloon-system-a-case-series
#9
Radha Bharathi Dhandapani, Shivakumar Baskaran, Kurumathur Vasudevan Arun, Thirunelveli Saravanan Subbu Kumar
The posterior maxillary segment frequently exhibits insufficient bone mass to support dental implants. Sinus floor augmentation enables implant placement in the posterior maxilla. This case series included ten sites, in which sinus floor elevation was done using sinus lift balloon system followed by augmentation utilizing irradiated cancellous bone allograft. Postoperative radiographic assessment of vertical bone gain was done at 3 and 6 months follow-up period. The mean initial and final bone height were 6...
July 2016: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/28298832/reconstruction-of-interdental-papilla-using-autogenous-bone-and-connective-tissue-grafts
#10
Santhanakrishnan Muthukumar, Pooja Ajit, Shiyamali Sundararajan, Suresh Ranga Rao
Previous studies have reported the management of Class I and II papillary defects, but knowledge on Class III defects, estimated to have a poor periodontal prognosis, remains minimal. In this case report, a Class III papillary defect reconstruction was attempted mainly since the patient reported with difficulty in phonetics. In Stage I, autogenous bone graft from the maxillary tuberosity and subepithelial connective tissue graft was augmented to decrease the distance between the interdental bone crest and contact point, simultaneously achieving a switch in the periodontal biotype...
July 2016: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/28298052/allograft-augmentation-of-hamstring-autograft-for-younger-patients-undergoing-anterior-cruciate-ligament-reconstruction
#11
Cale A Jacobs, Jeremy M Burnham, Eric Makhni, Chaitu S Malempati, Eric Swart, Darren L Johnson
BACKGROUND: Younger patients and those with smaller hamstring autograft diameters have been shown to be at significantly greater risk of graft failure after anterior cruciate ligament (ACL) reconstruction. To date, there is no information in the literature about the clinical success and/or cost-effectiveness of increasing graft diameter by augmenting with semitendinosus allograft tissue for younger patients. HYPOTHESIS: Hybrid hamstring grafts are a cost-effective treatment option because of a reduced rate of graft failure...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296552/enhanced-socs3-in-osteoarthiritis-may-limit-both-proliferation-and-inflammation
#12
T Gui, B S He, Q Gan, C Yang
Osteoarthritis (OA) is a degenerative joint disease that is characterized by localized inflammatory and secondary proliferative changes. Suppressor of cytokine signaling 3 (SOCS3) is elevated during OA development. We investigated the effects of this protein on human chondrocyte survival in OA and the inflammatory response together with the mechanisms of these effects. Small interfering RNA (siRNA) was used to knock down the expression of SOCS3 in interleukin(IL)-1β-induced primary human osteoarthritic chondrocytes...
2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/28295901/high-aldehyde-dehydrogenase-activity-identifies-a-subset-of-human-mesenchymal-stromal-cells-with-vascular-regenerative-potential
#13
Stephen E Sherman, Miljan Kuljanin, Tyler T Cooper, David M Putman, Gilles A Lajoie, David A Hess
During culture expansion, multipotent mesenchymal stromal cells (MSC) differentially express aldehyde dehydrogenase (ALDH), an intracellular detoxification enzyme that protects long-lived cells against oxidative stress. Thus, MSC selection based on ALDH-activity may be used to reduce heterogeneity and distinguish MSC subsets with improved regenerative potency. After expansion of human bone marrow-derived MSC, cell progeny were purified based on low versus high ALDH-activity by fluorescence activated cell sorting, and each subset was compared for multipotent stromal and pro-vascular regenerative functions...
March 15, 2017: Stem Cells
https://www.readbyqxmd.com/read/28294200/four-year-post-loading-results-of-full-arch-rehabilitation-with-immediate-placement-and-immediate-loading-implants-a-retrospective-controlled-study
#14
Alain Simonpieri, Roberta Gasparro, Giuseppe Pantaleo, Jolanda Mignogna, Francesco Riccitiello, Gilberto Sammartino
OBJECTIVES: The aim of this study was to evaluate implant survival rate and to measure peri-implant bone changes in fullarch rehabilitations with immediate placement and immediate loading implants with platform switching and Morse taper connection, in addition to platelet-rich fibrin (PRF) and buccal bone augmentation, after 4 years of follow-up. METHOD AND MATERIALS: In this retrospective controlled study, patients who had been fully rehabilitated with immediate placement and immediate loading implants were evaluated 4 years post-loading...
March 14, 2017: Quintessence International
https://www.readbyqxmd.com/read/28293752/acoustic-emission-signatures-during-failure-of-vertebra-and-long-bone
#15
Brian D Goodwin, Frank A Pintar, Narayan Yoganandan
Clinical classification of an injury has traditionally involved medical imaging, patient history, and physical examination. The pathogenesis or process of injury has been viewed as a crucial component to estimating fracture stability and direct treatment. However, injury classification systems generally exclude pathogenesis and injury mechanisms because these components are often difficult to elucidate. Furthermore, the development of bone damage relative to the mechanical response is difficult to quantify, which limits the ability to define injury and develop injury criteria...
March 14, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28291858/alveolar-ridge-dimension-6-months-after-implant-placement-with-simultaneous-hard-tissue-augmentation
#16
Siegfried Martin Heckmann, Barbara Mörtlbauer, Dominik Rieder, Manfred Wichmann, Tim Krafft, Antonios Moralis
PURPOSE: When failing front teeth are replaced by implants, vestibular bone deficiencies frequently require augmentation, even though the amount of missing alveolar volume may vary. The objective of this study was to analyze the horizontal alveolar ridge dimension after implant placement and simultaneous augmentation, and to compare it to the condition at the contralateral natural site. MATERIALS AND METHODS: Forty-eight patients with a failing maxillary incisor received an immediate or early implant (Straumann Bone Level), according to a randomized study protocol...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291857/effect-of-maxillary-sinus-membrane-perforation-on-implant-survival-rate-a-retrospective-study
#17
Carlos Eduardo de Almeida Ferreira, Carolina Borges Martinelli, Arthur Belém Novaes, Túlio Bonna Pignaton, Camila Coser Guignone, Adriana Luísa Gonçalves de Almeida, Eduardo Saba-Chujfi
PURPOSE: The aim of this retrospective study was to evaluate implant survival rates (ISRs) for implants placed in grafted sinuses where a membrane perforation occurred during augmentation using exclusively anorganic bovine bone (ABB) by means of clinical and radiographic examinations. Histologic information of five biopsy specimens taken from large membrane perforations is also presented. MATERIALS AND METHODS: Consecutive patients who underwent sinus augmentation procedures at a private practice Dental Institute between 2004 and 2013 were collected from a computer database...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291856/histologic-evaluation-of-sinus-grafting-materials-after-peri-implantitis-induced-failure-a-case-series
#18
Antonio Scarano, Anastasia Kelekis Cholakis, Adriano Piattelli
PURPOSE: This human case series presents the clinical and histologic results of five cases of peri-implantitis with subsequent sinus graft infections. Complications may follow maxillary sinus augmentation procedures. It is possible to have an inflammatory reaction, movement of the implant inside the sinus, formation of an insufficient quantity of osseous tissue, and the production of an oroantral fistula. Complications following maxillary subantral augmentation procedures are relatively rare; however, the risks and benefits of any surgery must be carefully evaluated at the onset...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291849/vertical-ridge-augmentation-in-the-atrophic-mandible-a-systematic-review-and-meta-analysis
#19
Basel Elnayef, Alberto Monje, Jordi Gargallo-Albiol, Pablo Galindo-Moreno, Hom-Lay Wang, Federico Hernández-Alfaro
PURPOSE: To systematically appraise the effectiveness/reliability of vertical ridge augmentation (VRA) in the atrophic mandible. Articles that addressed any one of the following four areas were included in this study: amount of VRA, implant survival (ISR) and success rates (SSR) in the area of newly regenerated bone, complication rate during the bone augmentation procedure, and bone resorption. MATERIALS AND METHODS: An electronic literature search was conducted by two independent reviewers in several databases, including MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cochrane Oral Health Group Trials Register databases for articles reporting VRA in the atrophic mandible via distraction osteogenesis (DO), inlay block grafting (IBG), onlay block grafting (OBG), and guided bone regeneration (GBR)...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291409/association-between-bicortical-screw-fixation-at-upper-instrumented-vertebra-and-risk-for-upper-instrumented-vertebra-fracture
#20
Young-Seop Park, Seung-Jae Hyun, Ho Yong Choi, Ki-Jeong Kim, Tae-Ahn Jahng
OBJECTIVE The aim of this study was to investigate the risk of upper instrumented vertebra (UIV) fractures associated with UIV screw fixation (unicortical vs bicortical) and polymethylmethacrylate (PMMA) augmentation after adult spinal deformity surgery. METHODS A single-center, single-surgeon consecutive series of adult patients who underwent lumbar fusion for ≥ 4 levels (that is, the lower instrumented vertebra at the sacrum or pelvis and the UIV of the thoracolumbar spine [T9-L2]) were retrospectively reviewed...
March 3, 2017: Journal of Neurosurgery. Spine
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