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https://www.readbyqxmd.com/read/28930778/radioprotection-with-amifostine-enhances-bone-strength-and-regeneration-and-bony-union-in-a-rat-model-of-mandibular-distraction-osteogenesis
#1
Catherine N Tchanque-Fossuo, Alexis Donneys, Sagar S Deshpande, Deniz Sarhaddi, Noah S Nelson, Laura A Monson, Sara E Dahle, Steve A Goldstein, Steven R Buchman
BACKGROUND: Using distraction osteogenesis (DO) to regenerate robust endogenous bone could greatly enhance postoncologic reconstruction of head and neck cancer. However, radiation (XRT) corrosive effects still preclude DO's immense potential. We posit that adjunctive pretreatment with the radioprotectant amifostine (AMF) can optimize wound healing and allow for successful DO with quantifiable enhancements in bony union and strength despite previous surgical bed irradiation. METHODS: Two groups of murine left hemimandibles were exposed to a human equivalent radiation dosage fractionated over 5 daily doses of 7 Gy...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28929203/effects-of-toothpastes-on-white-spot-lesions-around-orthodontic-brackets-using-quantitative-light-induced-fluorescence-qlf-an-in-vitro-study
#2
Gokcenur Gokce, Selcuk Savas, Ebru Kucukyilmaz, Ilknur Veli
AIM: The aim of this study was to investigate the effects of toothpastes with different contents on the remineralization of white spot lesions around orthodontic brackets by quantitative light-induced fluorescence (QLF). MATERIALS AND METHODS: A total of 45 freshly extracted human mandibular first molars were selected. Artificial caries lesions were created on enamel surfaces using an acidified gel system for 7 days. Initial relative fluorescence loss was calculated as the pretreatment (baseline) fluorescence value by QLF device...
September 19, 2017: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/28927954/systematic-three-dimensional-analysis-of-wafer-based-maxillary-repositioning-procedures-in-orthognathic-surgery
#3
Timo Dreiseidler, Max-Philipp Lentzen, Matthias Zirk, Ali-Farid Safi, Joachim E Zoeller, Matthias Kreppel
PURPOSE: Little is known about the three-dimensional (3D) transfer accuracy in maxillary repositioning procedures based on conventionally manufactured dental-mounted wafers. The purpose of the present study was a systematic 3D analysis for wafer-based maxillary positioning in orthognathic surgery. MATERIALS AND METHODS: A total of 92 patients underwent Le Fort I in addition to mandibular bilateral sagittal split osteotomies (BSSO). Alignment of the pre- and postsurgical CBCT data sets allowed measuring maxillary position changes in axial, sagittal and transversal directions...
August 31, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28912722/repeated-mandibular-extension-in-rat-a-procedure-to-modulate-the-cerebral-arteriolar-tone
#4
Dominga Lapi, Maurizio Varanini, Antonio Colantuoni, Cristina Del Seppia, Sergio Ghione, Enza Fommei, Rossana Scuri
Previous data have shown both in the rat and in the human that a single mandibular extension lasting 10 min induces a significant important and prolonged reduction in blood pressure and heart rate, affecting also rat pial microcirculation by the release of endothelial factors. In the present work, we assessed whether repeated mandibular extension could further prolong these effects. We performed two mandibular extensions, the second mandibular extension being applied 10 min after the first one. The second mandibular extension produced a reduction in blood pressure and heart rate for at least 240 min...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28910382/refining-experimental-dental-implant-testing-in-the-g%C3%A3-ttingen-minipig-using-3d-computed-tomography-a-morphometric-study-of-the-mandibular-canal
#5
Giuliano M Corte, Johanna Plendl, Hana Hünigen, Kenneth C Richardson, Ole Gemeinhardt, Stefan M Niehues
This study reports morphometric and age-related data of the mandibular canal and the alveolar ridge of the Göttingen Minipig to avoid complications during in vivo testing of endosseus dental implants and to compare these data with the human anatomy. Using 3D computed tomography, six parameters of the mandibular canal as well as the alveolar bone height and the alveolar ridge width were measured in Göttingen Minipigs aged 12, 17 and 21 months. Our null hypothesis assumes that the age and the body mass have an influence on the parameters measured...
2017: PloS One
https://www.readbyqxmd.com/read/28893644/high-bone-mass-due-to-novel-lrp5-and-amer1-mutations
#6
Alice Costantini, Päivi Kekäläinen, Riikka E Mäkitie, Outi Mäkitie
WNT signaling is a key regulator of bone metabolism and its increased or decreased activity leads to skeletal disorders. Here we describe two patients with high bone mass (HBM) caused by novel mutations in two different WNT pathway components. The first patient is a 53-year-old male with HBM. He was diagnosed at adult age based on significantly increased bone mineral density (BMD). He has undergone several surgeries due to excessive bone in ear canals, bilateral jaw exostoses and mandibular tori. Radiographs show severe cortical thickening of cranial and long bones...
September 8, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28891594/effect-of-telescopic-distal-extension-removable-partial-dentures-on-oral-health-related-quality-of-life-and-maximum-bite-force-a-preliminary-cross-over-study
#7
Moustafa Abdou Elsyad, Aisha Zakaria Mostafa
OBJECTIVES: This cross over study aimed to evaluate the effect of telescopic distal extension removable partial dentures on oral health related quality of life and maximum bite force MATERIALS AND METHODS: Twenty patients with complete maxillary edentulism and partially edentulous mandibles with anterior teeth only remaining were selected for this cross over study. All patients received complete maxillary dentures and mandibular partial removable dental prosthesis (PRDP, control). After 3 months of adaptation, PRDP was replaced with conventional telescopic partial dentures (TPD) or telescopic partial dentures with cantilevered extensions (TCPD) in a quasi-random method...
September 11, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28891406/clinical-practice-guideline-evaluation-of-the-neck-mass-in-adults
#8
Melissa A Pynnonen, M Boyd Gillespie, Benjamin Roman, Richard M Rosenfeld, David E Tunkel, Laura Bontempo, Itzhak Brook, Davoren Ann Chick, Maria Colandrea, Sandra A Finestone, Jason C Fowler, Christopher C Griffith, Zeb Henson, Corinna Levine, Vikas Mehta, Andrew Salama, Joseph Scharpf, Deborah R Shatzkes, Wendy B Stern, Jay S Youngerman, Maureen D Corrigan
Objective Neck masses are common in adults, but often the underlying etiology is not easily identifiable. While infections cause most of the neck masses in children, most persistent neck masses in adults are neoplasms. Malignant neoplasms far exceed any other etiology of adult neck mass. Importantly, an asymptomatic neck mass may be the initial or only clinically apparent manifestation of head and neck cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, or salivary gland cancer. Evidence suggests that a neck mass in the adult patient should be considered malignant until proven otherwise...
September 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28888409/maxillofacial-prosthetic-treatment-factors-affecting-oral-health-related-quality-of-life-after-surgery-for-patients-with%C3%A2-oral-cancer
#9
Miki Hagio, Ken Ishizaki, Masahiro Ryu, Takeshi Nomura, Nobuo Takano, Kaoru Sakurai
STATEMENT OF PROBLEM: After oral cancer surgery, tissue defects can cause deformity and limited mobility, complicating many essential functions. For patients with mandibular, tongue, and oral floor defects, evidence regarding the effects of maxillofacial prosthetics on their oral health-related quality of life (OHRQoL) is lacking. Therefore, maxillofacial prosthetic reconstruction has been implemented with no clear treatment goals. PURPOSE: The purpose of this study was to identify factors affecting the improvement of OHRQoL by using maxillofacial prosthetic treatment after surgery to repair maxillary, mandibular, tongue, and oral floor defects...
September 6, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28883677/comparison-of-results-of-measurement-of-dimensions-of-the-placed-dental-implants-on-cone-beam-computed-tomography-with-dimensions-of-the-producers-of-the-implants
#10
Merisa Repesa, Amela Sofic, Selma Jakupovic, Selma Tosum, Lejla Kazazic, Almir Dervisevic
INTRODUCTION: One of the most frequently used method for scanning patients with indication for dental implantation in dentistry is cone beam computed tomography. Implantation, CBCT imaging and implant programme are inevitable when planning a successful replacement of lost teeth. CBCT offers exact information about available bone and its density, adjacent tooth roots, the place of mandibular canal and maxillary sinus and adjacent anatomical structure. AIM: The goal of this study is to estimate accuracy of measurements on CBCT images ofpatients who have implants of different producers and determine if there is any statistically significant correlation between four test groups regardless of the alloy of which implants are made...
June 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28882499/secondary-surgical-management-of-osteoradionecrosis-using-three-dimensional-isodose-curve-visualization-a-report-of-three-cases
#11
J Kraeima, R J H M Steenbakkers, F K L Spijkervet, J L N Roodenburg, M J H Witjes
Osteoradionecrosis is defined as bone death secondary to radiotherapy. There is a relationship between the radiation dose received and the occurrence of osteoradionecrosis of the jaws, with the risk increasing above a dose of 60Gy. In cases of class III mandibular osteoradionecrosis, a segmental resection can be indicated. Current practice is to completely remove the affected bone up to the point where the bone looks healthy and is bleeding. Exact resection planning and the use of guided surgery based on imaging of the bone changes have not been reported so far...
September 4, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28879337/hemodynamic-changes-and-pain-perception-related-anxiety-after-experiencing-an-impacted-tooth-removal-clinical-practice-outcome
#12
Somchart Raocharernporn, Kiatanant Boonsiriseth, Manop Khanijou, Natthamet Wongsirichat
BACKGROUND: Dental fear is usually associated with hemodynamic changes. Fear of pain during the surgical removal of a lower impacted third molar might cause patients anxiety, thereby leading to avoidance of any future dental therapy. This study aimed to determine the effect of experiencing a surgical impacted-tooth removal on the pain perception-related anxiety and hemodynamic status. METHODS: Twenty-seven healthy patients aged 15-30 years (mean age, 24 years), for whom surgical removal of bilateral lower third molars was advised, were included...
June 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/28875566/structure-and-development-of-the-subesophageal-zone-of-the-drosophila-brain-ii-sensory-compartments
#13
Sarah Kendroud, Ali Asgar Bohra, Philipp A Kuert, Bao Nguyen, Oriane Guillermin, Simon G Sprecher, Heinrich Reichert, Krishnaswamy VijayRaghavan, Volker Hartenstein
The subesophageal zone (SEZ) of the Drosophila brain processes mechanosensory and gustatory sensory input from sensilla located on the head, mouth cavity and trunk. Motor output from the SEZ directly controls the movements involved in feeding behavior. In an accompanying paper (Hartenstein et al., 2017) we analyzed the systems of fiber tracts and secondary lineages to establish reliable criteria for defining boundaries between the four neuromeres of the SEZ, as well as discrete longitudinal neuropil domains within each SEZ neuromere...
September 6, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28875137/risk-factor-analysis-of-additional-administration-of-sedative-agent-and-patient-dissatisfaction-in-intravenous-conscious-sedation-using-midazolam-for-third-molar-extraction
#14
Dong-Whan Shin, Jin-Yong Cho, Yoon-Sic Han, Hye-Young Sim, Hee-Sun Kim, Da-Un Jung, Ho Lee
OBJECTIVES: The primary purpose of this study was to investigate the factors related with additional administration of sedative agent during intravenous conscious sedation (IVS) using midazolam (MDZ). The secondary purpose was to analyze the factors affecting patient satisfaction. MATERIALS AND METHODS: Clinical data for 124 patients who had undergone surgical extraction of mandibular third molar under IVS using MDZ were retrospectively investigated in this case-control study...
August 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28872507/protection-of-the-temporomandibular-joint-during-syndromic-mandibular-distraction-with-a-novel-condylar-offloading-device
#15
Sagar T Mehta, Neal Moores, Duane Yamashiro, Faizi Siddiqi, Barbu Gociman
Mandibular distraction for severe micrognathia in syndromic patients often leads to temporomandibular joint (TMJ) ankylosis, which requires further interventions to regain joint motion. The increased incidence of postdistraction ankylosis is likely related to increased prevalence of preoperative joint pathology in syndromic micrognathic patients. Previous studies have demonstrated that offloading the pressure on the condyle during the distraction process can prevent such TMJ pathology. In this article, the authors describe a successful new method for offloading the condyle to prevent postdistraction ankylosis using an external TMJ offloading device...
September 1, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28871830/comparison-of-panoramic-radiography-and-cone-beam-ct-in-the-assessment-of-juxta-apical-radiolucency
#16
Eduarda Hl Nascimento, Anne Cc Oenning, Hugo Gaêta-Araujo, Francisco Haiter-Neto, Bernardo B Freire, Deborah Q Freitas
OBJECTIVES: To compare the performance of panoramic radiography (PAN) and cone beam computed tomography (CBCT) in the detection of juxta-apical radiolucency (JAR), as well as to investigate, in CBCT images, if there are factors associated with the detection of JAR on PAN. METHODS: Two oral radiologists assessed the presence of JAR in PAN and CBCT images of 175 individuals (308 mandibular third molars). The cortical plates involvement and the JAR size and location were assessed on CBCT to evaluate if these factors were related to JAR detection on PAN...
September 5, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28867462/use-of-cone-beam-computed-tomography-to-assess-significant-imaging-findings-related-to-mandibular-third-molar-impaction
#17
Louise Hauge Matzen, Lars Schropp, Rubens Spin-Neto, Ann Wenzel
OBJECTIVE: The aim of the study was to identify risk factors for pathoses related to mandibular third molars observed in cone beam computed tomography. STUDY DESIGN: Cone beam computed tomography volumes of 410 mandibular third molars were assessed by 3 observers, according to the angulation and position of the third molar in relation to the second molar. In addition, pathoses (marginal bone loss, resorption of the second molar, increased follicular space and lingual bone perforation) were assessed...
August 2, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28866360/quantitative-assessment-of-mandibular-canal-compression-assessed-by-cone-beam-computed-tomography
#18
Fatima M Jadu, Daniah Alhazmi, Fatma F Badr, Ahmed M Jan
OBJECTIVE: The aim of this study was to objectively quantify the topographic relation of the mandibular canals, impacted third molars, and cortical plates using cone beam computed tomography (CBCT). STUDY DESIGN: A retrospective chart review was conducted using the database of a university-based imaging service. Two calibrated reviewers examined the CBCT images of 100 cases scheduled for mandibular third molar removal. They characterized the position and condition of the mandibular canal and measured its dimensions at 3 different points relative to the third molars...
August 2, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28866048/subcutaneous-lipoatrophy-and-skin-depigmentation-secondary-to-tmj-intra-articular-corticosteroid-injection
#19
Nicolás Patricio Skármeta, Fernando Ariel Hormazábal, Juan Alvarado, Ana Maria Rodriguez
Chronic orofacial pain is a complex multidimensional experience that produces disability and impairment of normal mandibular function. Overall estimations of chronic orofacial pain prevalence are 7 to 11% of the general population. Temporomandibular disorders (TMDs) are one of the most prevalent chronic orofacial pain conditions, with temporomandibular joint (TMJ) arthralgia accounted for 30.1% of TMD patients. Interventional procedures are often used in pain and palliative medicine to achieve reasonable and cost-effective pain relief...
August 5, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28865818/single-vs-2-implants-on-peri-implant-marginal-bone-level-and-implant-failures-in-mandibular-implant-overdentures-a-systematic-review-with-meta-analysis
#20
REVIEW
Dina Mohamed Ahmed Elawady, Amal Fathy Kaddah, Mohamed Talaat Khalifa
BACKGROUND: As a consensus, the 2-implant supported overdentures (ODs) are considered as the first choice of treatment for the edentulous mandible. In the same context, there is increased evidence supporting the use of single-implant OD. The aim of any design is to preserve the remaining structures and allow the longevity of the treatment. OBJECTIVES: To evaluate the impact of single implant vs 2 implants on the peri-implant marginal bone loss (MBL) and number of implant failures in mandibular implant overdentures...
September 2017: Journal of Evidence-based Dental Practice
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