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https://www.readbyqxmd.com/read/28087282/short-term-perioperative-teriparatide-therapy-for-the-prevention-of-medication-related-osteonecrosis-of-the-jaw-a-randomized-controlled-preclinical-study-in-rats
#1
Mohammad Zandi, Arash Dehghan, Amirhossein Mohammadi-Mofrad, Payam Amini, Farshid Vahdatinia
OBJECTIVE: Dentoalveolar procedures in patients receiving bisphosphonates and other antiresorptive agents are associated with an increased risk of medication-related osteonecrosis of the jaw (MRONJ). The aim of present study was to evaluate the effects of perioperative teriparatide (TPD) therapy in prevention of MRONJ. SUBJECTS AND METHODS: Two protocols of TPD therapy were studied. For protocol A, 25 TPD-treated (AT) and 25 control (AC) rats received 5 weekly injection of 0...
December 19, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28078129/osteonecrosis-of-the-jaw-associated-with-ziv-aflibercept
#2
Hani Mawardi, Peter Enzinger, Nadine McCleary, Reshma Manon, Alessandro Villa, Nathaniel Treister, Sook-Bin Woo
Medication-related osteonecrosis of the jaw (MRONJ) has been associated with medications that include bisphosphonates (BPs), denosumab, bevacizumab and sunitinib. Ziv-aflibercept is a recombinant human vascular endothelial growth factor (VEGF) receptor which has been used to treat patients with various advanced solid tumors. We report three patients without a history of the use of medications known to cause MRONJ presenting with jaw osteonecrosis typical for MRONJ following therapy with ziv-aflibercept. All patients had metastatic gastrointestinal cancer treated with ziv-aflibercept and were evaluated for MRONJ because of exposed bone in the oral cavity...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28076458/risk-of-developing-palatally-displaced-canines-in-patients-with-early-detectable-dental-anomalies-a-retrospective-cohort-study
#3
Daniela Gamba Garib, Melissa Lancia, Renata Mayumi Kato, Thais Marchini Oliveira, Lucimara Teixeira das Neves
Objective: To estimate the risk of PDC occurrence in children with dental anomalies identified early during mixed dentition. Material and Methods: The sample comprised 730 longitudinal orthodontic records from children (448 females and 282 males) with an initial mean age of 8.3 years (SD=1.36). The dental anomaly group (DA) included 263 records of patients with at least one dental anomaly identified in the initial or middle mixed dentition. The non-dental anomaly group (NDA) was composed of 467 records of patients with no dental anomalies...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28073624/european-college-of-orthodontics-commission-of-affiliation-and-titularisation
#4
Alexis Moreau
: Date of birth: 2/8/1982; sex: male. A. PRETREATMENT RECORDS: 25 years; 7/3/2008. DIAGNOSIS: Very severe Class III malocclusion in adult dentition in hyperdivergent facial pattern; Sagittal dimension: skeletal and dental Class II, severe alveolar retrusion of the mandibular incisors, negative overjet (-11mm); transverse dimension: Class III-related bilateral crossbite with no transverse maxillary deficiency; vertical dimension: incisor overbite, increased height of the lower facial third; Teeth missing prior to treatment: 16-26...
January 7, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28068264/locator-retention-does-variation-in-number-and-configuration-matter
#5
Monica J Cayouette, Logan Barnes, Karen McPherson, Gregory J Wright
This pilot study was designed to collect initial data on overdenture attachment retention in varying configurations of attachment location in an implant-retained mandibular overdenture. A clear acrylic model of a mandible with 6 numbered implants and Locator resilient abutments was used to simulate implant placement in a patient. A clear acrylic denture was fabricated with 6 Locator housings to match the implants in the model. Attachments were tested in 4 different configurations: 2 implants, 2 and 5 (T25); 4 implants, 2-5 (T2345); 4 implants, 1, 3, 4, and 6 (T1346); and 6 implants, 1-6 (T1-6)...
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28065707/craniofacial-characteristics-in-the-sagittal-dimension-a-cephalometric-study-in-lebanese-young-adults
#6
Antoine Daraze, Myriam Delatte, Sami Bou Saba, Zeina Majzoub
OBJECTIVES: The purpose of this study was to assess the sagittal cephalometric characteristics of young adult Lebanese individuals and assess gender-related differences. MATERIALS AND METHODS: Conventional lateral cephalograms were obtained from 117 subjects. Eight linear/angular measurements combining sagittal parameters selected form McNamara and Steiner analyses were recorded. Paired t-test was applied to evaluate differences between genders and skeletal classes...
January 5, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28065645/mandibular-reconstruction-with-vascularised-bone-flaps-a-systematic-review-over-25-years
#7
REVIEW
J S Brown, D Lowe, A Kanatas, A Schache
To explore the techniques for mandibular reconstruction with composite free flaps and their outcomes, we systematically reviewed reports published between 1990 and 2015. A total of 9499 mandibular defects were reconstructed with 6178 fibular, 1380 iliac crest, 1127 composite radial, 709 scapular, 63 serratus anterior and rib, 32 metatarsal, and 10 lateral arm flaps including humerus. The failure rate was higher for the iliac crest (6.2%, 66/1059) than for fibular, radial, and scapular flaps combined (3.4%, 202/6018) (p<0...
January 5, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28061356/clinical-differences-in-autofluorescence-between-viable-and-nonvital-bone-a-case-report-with-histopathologic-evaluation-performed-on-medication-related-osteonecrosis-of-the-jaws
#8
Ilaria Giovannacci, Marco Meleti, Domenico Corradi, Paolo Vescovi
Medication-related osteonecrosis of the jaws (MRONJ) is an adverse side effect of several drug therapies, including bisphosphonates (BPs). Osteonecrosis of the jaw specifically related to BP therapy is usually referred to using the acronym BRONJ. However, no consensus has yet been reached regarding the most appropriate management of BRONJ. The greatest success rates have been recorded with surgical removal of necrotic bone. In particular, erbium:yttrium-aluminum-garnet (Er:YAG) laser-assisted surgery has shown significantly better results than conventional surgical approaches...
December 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28056959/morphological-densitometric-and-mechanical-properties-of-mandible-in-5-month-old-polish-merino-sheep
#9
Anna Szabelska, Marcin R Tatara, Witold Krupski
BACKGROUND: Among bones building the axial and appendicular skeleton, the mandible is characterized by unique morphological and functional traits. The aim of the study was to evaluate morphological, densitometric and mechanical properties of mandible in 5-month-old Polish Merino sheep. Using quantitative computed tomography, volumetric bone mineral density (vBMD) and calcium hydroxyapatite density of the cortical bone (CbCa-HA), mean vBMD (MvBMD) and total bone volume were determined...
January 5, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28050992/dautrey-s-procedure-revisited-in-management-of-recurrent-mandibular-dislocation
#10
Joanna Baptist, Mohan Baliga
Mandibular dislocation occurs when the condylar head glides out of the glenoid fossa with the condyle positioned in such a way that its posterior articulating surface lying ahead of the articular eminence. Recurrent mandibular dislocation is relatively uncommon. Patient is extremely distressed and goes through a lot of discomfort. Varied etiologies have been cited in the literature, such as keeping the mouth wide open for long periods of time during dental procedures, yawning, laughing, traumatic injuries to the mandible, psychiatric disturbances, and certain drugs...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28050985/patients-awareness-toward-implant-supported-prosthesis-an-observational-study
#11
C Mahendra Raju, Sumanth Gunupati, Madisetty Mahesh Babu, C Sameer Kumar Reddy, Sukrutha Biradavolu, M Saravanan
INTRODUCTION: Implant-supported prosthesis has high predictability and success and improves quality of life. This study aims at assessing awareness among the patients regarding implant-supported prosthesis. MATERIALS AND METHODS: A cross-sectional study was conducted among 391 study participants. A structured questionnaire was distributed to assess implant-related awareness among the study participants. The questionnaires were analyzed for the responses. RESULTS: Among the 391 respondents, 37...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28050063/a-radiographic-study-of-external-apical-root-resorption-in-patients-treated-with-single-phase-fixed-orthodontic-therapy
#12
S S Agarwal, S S Chopra, Prasanna Kumar, B Jayan, K Nehra, Mohit Sharma
BACKGROUND: External apical root resorption (EARR) is one of the most common iatrogenic consequences of orthodontic tooth movement. Many factors like gender, duration, orthodontic force and duration of orthodontic treatment have been implicated to cause EARR. METHODS: Pre- and post-treatment OPGs of 60 orthodontic patients (30 males and 30 females) who had undergone treatment with a single phase of fixed orthodontic therapy were randomly selected from institutional archives...
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28045346/utility-of-fusion-volumetric-images-from-computed-tomography-and-magnetic-resonance-imaging-for-localizing-the-mandibular-canal
#13
Chutamas Deepho, Hiroshi Watanabe, Shinya Kotaki, Junichiro Sakamoto, Yasunori Sumi, Tohru Kurabayashi
OBJECTIVES: The purpose of this study is to investigate whether computed tomography/magnetic resonance imaging (CT/MRI) fusion volumetric images can improve the detectability of the mandibular canal (MC) compared to CT alone. METHODS: Images of 31 lesions within or close to the mandible using both multi-slice CT (MSCT) and MRI were gathered from our imaging archives. All lesions underwent MSCT and three dimensional volumetric interpolated breath-hold examination (3D-VIBE) MRI...
January 3, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28043745/the-efficacy-of-hyperbaric-oxygen-therapy-related-to-the-clinical-stage-of-osteoradionecrosis-of-the-mandible
#14
F J Dieleman, T T T Phan, F J A van den Hoogen, J H A M Kaanders, M A W Merkx
This study aimed to evaluate the success of hyperbaric oxygen therapy (HBOT) and surgery in the treatment of mandibular osteoradionecrosis (ORN) in relation to the extent of the ORN. Twenty-seven patients with ORN were identified from a total of 509 patients with a history of primary oral or base of the tongue cancer; these patients had been treated with radiation therapy with curative intent between 1992 and 2006, with a radiation dose to the mandible of ≥50Gy. The ORN was staged according to the classification of Notani et al...
December 30, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28042265/comparative-evaluation-of-platelet-rich-fibrin-versus-beta-tri-calcium-phosphate-in-the-treatment-of-grade-ii-mandibular-furcation-defects-using-cone-beam-computed-tomography
#15
Zeba Rahman Siddiqui, Rajesh Jhingran, Vivek Kumar Bains, Ruchi Srivastava, Rohit Madan, Iram Rizvi
OBJECTIVE: The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus β-tri-calcium phosphate (β-TCP) in the treatment of Grade II mandibular furcation defects. MATERIALS AND METHODS: Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (n = 15), to OFD with β-TCP Group II (n = 15), and to OFD alone Group III (n = 15) were analyzed for clinical parameters (probing pocket depth [PPD], vertical clinical attachment level [VCAL], horizontal clinical attachment level [HCAL], gingival recession, relative vertical height of furcation [r-VHF], and relative horizontal depth of furcation [r-HDF]) and radiographical parameters (horizontal depth of furcation [H-DOF], vertical height of furcation [V-HOF]) using cone-beam computed tomography (CBCT) at 6 months interval...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28041843/predictive-value-of-panoramic-radiography-for-injury-of-inferior-alveolar-nerve-after-mandibular-third-molar-surgery
#16
Naichuan Su, Arjen van Wijk, Erwin Berkhout, Gerard Sanderink, Jan De Lange, Hang Wang, Geert J M G van der Heijden
PURPOSE: The purpose of the present systematic review was to assess the added value of panoramic radiography in predicting postoperative injury of the inferior alveolar nerve (IAN) in the decision-making before mandibular third molar (MM3) surgery. MATERIALS AND METHODS: MEDLINE and EMBASE were searched electronically to identify the diagnostic accuracy of studies that had assessed the predictive value of 7 panoramic radiographic signs, including root-related signs (darkening of the root, deflection of the root, narrowing of the root, and dark and bifid apex of the root) and canal-related signs (interruption of the white line of the canal, diversion of the canal, and narrowing of the canal) for IAN injury after MM3 surgery...
December 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28039546/the-relationship-between-lateral-displacement-of-the-mandible-and-scoliosis
#17
Azusa Nakashima, Hiroyuki Nakano, Tomohiro Yamada, Kazuya Inoue, Goro Sugiyama, Wataru Kumamaru, Yasumichi Nakajima, Tomoki Sumida, Takeshi Yokoyama, Katsuaki Mishiama, Yoshihide Mori
OBJECTIVES: Idiopathic scoliosis is an orthopaedic disease of childhood, with onset and progress occurring until adolescence. Here, the relationship between lateral displacement of the mandible and scoliosis was analysed quantitatively. METHODS: Seventy-nine non-syndromic Japanese patients (18 men, 61 women), who were diagnosed with jaw deformities and underwent surgical orthognathic treatment at Kyushu University Hospital from January 2011 to August 2014, were enrolled...
December 30, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28039008/risk-factors-for-severe-complications-of-operative-mandibular-fractures
#18
Brian J Christensen, Donald E Mercante, John P Neary, Brett J King
PURPOSE: The purpose of the present study was to identify the risk factors for major complications developing during the operative treatment of mandibular fractures. PATIENTS AND METHODS: We conducted a retrospective medical record review of patients who had undergone open reduction, internal fixation of mandibular fractures from August 1, 2012 to December 31, 2014 at a large, urban teaching hospital and level 1 trauma center. The outcome variable of interest was major complications, defined as the occurrence of any one of the following events: hospital readmission, return to the operating room, and a prolonged, unexpected postoperative stay...
December 11, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28034533/audiological-features-in-congenital-bony-atresia-of-external-auditory-canal-with-temporal-mandibular-joint-retroposition
#19
Ran Ren, Shouqin Zhao, Danni Wang, Lin Yang, Zhonglin Liu, Ying Li, Chenyi Wei
OBJECTIVES: To facilitate the diagnosis, treatment and surgical options for congenital bony atresia of external auditory canal (EAC) with temporal-mandibular joint (TMJ) retroposition by analyzing its audiological features and the morphology of temporal bone on CT scan. MATERIALS AND METHODS: Two cohorts of patients with congenital EAC bony atresia with (n=23) or without (n=21) TMJ retroposition were recruited from September 2012 to July 2014 at Beijing Tongren Hospital, Capital Medical University...
October 3, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28033685/clinical-anatomy-and-surgical-significance-of-the-lingual-foramina-and-their-canals
#20
REVIEW
Puhan He, Mindy K Truong, Nimer Adeeb, R Shane Tubbs, Joe Iwanaga
The lingual foramina and canals can be categorized as medial or lateral based on their relation to the midline of the mandible. Investigation of the mandibular lingual region is often done with gross anatomical dissections of cadavers, 2D panoramic radiographic imaging, CT and cone beam CT (CBCT). While gross studies are the most reliable at qualifying canal contents and course, CBCT proved to be superior to other radiographic techniques for visualizing lingual foramina and canals. The submental and sublingual arteries, and their branches are found in the lingual vascular canals...
December 29, 2016: Clinical Anatomy
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