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Underactive bladder

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https://www.readbyqxmd.com/read/27847918/does-uroflowmetry-parameter-facilitate-discrimination-between-detrusor-underactivity-and-bladder-outlet-obstruction
#1
Kwon Soo Lee, Phil Hyun Song, Young Hwii Ko
PURPOSE: Though urodynamic study (UDS) is the current established standard to distinguish between detrusor underactivity (DU) and bladder outlet obstruction (BOO), concerns of patient discomfort and potential complications of catheterization deters its use. We inspected clinical variables to discriminate between DU and BOO in uroflowmetry, which can be more easily performed in clinical practice. MATERIALS AND METHODS: Total 240 men who both underwent UDS and uroflowmetry were reviewed...
November 2016: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/27798943/effects-of-distigmine-on-electrical-field-stimulation-induced-contraction-of-mouse-urinary-bladder-smooth-muscles
#2
Keisuke Obara, Yurina Kobayashi, Daisuke Chino, Yoshio Tanaka
Distigmine bromide (distigmine), a reversible carbamate cholinesterase inhibitor, is used in Japan for treating detrusor underactivity, myasthenia gravis, and glaucoma. Although there is clinical evidence about the effectiveness of distigmine in the treatment of detrusor underactivity, mechanisms by which distigmine restores impaired urinary bladder smooth muscle (UBSM) contractility have not been fully investigated. The aims of this study were to investigate the potentiating effects of distigmine on UBSM contractions in response to parasympathetic nerve stimulation induced by electrical field stimulation (EFS) in mice...
November 1, 2016: Pharmacology
https://www.readbyqxmd.com/read/27751474/re-unravelling-detrusor-underactivity-development-of-a-bladder-outlet-resistance-bladder-contractility-nomogram-for-adult-male-patients-with-lower-urinary-tract-symptoms
#3
https://www.readbyqxmd.com/read/27751468/re-factors-impacting-bladder-underactivity-and-clinical-implications
#4
Alan J Wein
No abstract text is available yet for this article.
November 2016: Journal of Urology
https://www.readbyqxmd.com/read/27751467/re-detrusor-underactivity-and-the-underactive-bladder-symptoms-function-cause-what-do-we-mean-ici-rs-think-tank-2014
#5
Alan J Wein
No abstract text is available yet for this article.
November 2016: Journal of Urology
https://www.readbyqxmd.com/read/27687821/systematic-review-of-the-performance-of-noninvasive-tests-in-diagnosing-bladder-outlet-obstruction-in-men-with-lower-urinary-tract-symptoms
#6
Sachin Malde, Arjun K Nambiar, Roland Umbach, Thomas B Lam, Thorsten Bach, Alexander Bachmann, Marcus J Drake, Mauro Gacci, Christian Gratzke, Stephan Madersbacher, Charalampos Mamoulakis, Kari A O Tikkinen, Stavros Gravas
CONTEXT: Several noninvasive tests have been developed for diagnosing bladder outlet obstruction (BOO) in men to avoid the burden and morbidity associated with invasive urodynamics. The diagnostic accuracy of these tests, however, remains uncertain. OBJECTIVE: To systematically review available evidence regarding the diagnostic accuracy of noninvasive tests in diagnosing BOO in men with lower urinary tract symptoms (LUTS) using a pressure-flow study as the reference standard...
September 26, 2016: European Urology
https://www.readbyqxmd.com/read/27547465/the-challenges-in-the-diagnosis-of-detrusor-underactivity-in-clinical-practice-a-mini-review
#7
REVIEW
Ahmed Ahmed, Bilal Farhan, Simone Vernez, Gamal M Ghoniem
OBJECTIVE: To review the current definitions, terminology, epidemiology and aetiology of detrusor underactivity (DU), with specific attention to the diagnostic criteria in use. In addition, we address the relation and the overlap between DU and bladder outlet obstruction (BOO). In this mini-review, we hope to help identify DU patients and facilitate structured clinical evaluation and research. METHODS: We searched the English literature using ScienceDirect and PubMed for relevant articles...
September 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27473156/a-cross-sectional-study-in-the-usa-of-the-epidemiology-and-quality-of-life-of-underactive-bladder-symptoms
#8
Kassem Faraj, Florence Doo, Judy Boura, Andrew Vereecke, Michael B Chancellor
PURPOSE: To assess the prevalence, awareness, and quality of life (QOL) impact of symptoms suggestive of underactive bladder (UAB) in the USA. METHODS: A thirteen-item paper survey was mailed to 25,000 individuals 60 years or older living in the USA. It aimed to collect information relating to demographics, familiarity with UAB, patient urinary symptoms, and QOL concerns. RESULTS: Nine hundred and seventy-seven survey participants were stratified into four groups based on the number of UAB symptoms (straining, retention, and difficulty emptying) present: zero, one, two, and three...
November 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27460338/phenotyping-women-with-detrusor-underactivity-by-presumed-etiology-is-it-plausible
#9
Elizabeth T Brown, Joshua A Cohn, Melissa R Kaufman, Roger R Dmochowski, William S Reynolds
AIMS: Underactive bladder (UAB) is a symptom complex with poorly characterized causation. The aim of this study was to determine if clinical and UDS parameters differed between categories of presumed detrusor underactivity (DU) etiologies. METHODS: A retrospective review was performed at a single institution from 2011 to 2015 to identify patients with symptoms of UAB. Patients were excluded if they were male, had anti-incontinence, or pelvic organ prolapse (POP) surgery within 1 year, or the UDS did not demonstrate DU as defined within...
July 26, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27450935/long-term-efficacy-of-holmium-laser-enucleation-of-the-prostate-in-patients-with-detrusor-underactivity-or-acontractility
#10
Derek J Lomas, Amy E Krambeck
OBJECTIVE: To evaluate long-term outcomes for men with benign prostatic obstruction (BPO) and concurrent detrusor underactivity (DUA) or acontractility following holmium laser enucleation of the prostate (HoLEP). METHODS: A retrospective chart review was performed on all patients with BPO and urodynamic evidence of DUA or acontractility secondary to a nonneurogenic etiology that underwent HoLEP at our institution over a 4-year period. Patients were included if they had at least 24 months of follow-up...
July 19, 2016: Urology
https://www.readbyqxmd.com/read/27447991/ultrasound-detrusor-wall-thickness-measurement-in-combination-with-bladder-capacity-can-safely-detect-detrusor-underactivity-in-adult-men
#11
Kevin L J Rademakers, Gommert A van Koeveringe, Matthias Oelke
PURPOSE: Detrusor underactivity (DU) has lately gained increasing interest because this bladder condition is an important cause of post-void residual urine and lower urinary tract symptoms (LUTS) in adult men. Until now, DU can only be diagnosed by pressure-flow measurement. Therefore, the aim of this study was to search for noninvasive tests which can safely predict DU in adult men. METHODS: Unselected, treatment-naïve male patients aged ≥40 years with uncomplicated, non-neurogenic LUTS were prospectively evaluated...
July 22, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27444952/the-potential-role-of-unregulated-autonomous-bladder-micromotions-in-urinary-storage-and-voiding-dysfunction-overactive-bladder-and-detrusor-underactivity
#12
Marcus J Drake, Anthony Kanai, Dominika A Bijos, Youko Ikeda, Irina Zabbarova, Bahareh Vahabi, Christopher H Fry
The isolated bladder shows autonomous micromotions, which increase with bladder distension, generate sensory nerve activity, and are altered in models of urinary dysfunction. Intravesical pressure resulting from autonomous activity putatively reflects three key variables; the extent of micromotion initiation, distances over which micromotions propagate, and overall bladder tone. In vivo, these variables are subordinate to the efferent drive of the central nervous system. In the micturition cycle storage phase, efferent inhibition keeps autonomous activity generally at a low level, where it may signal 'state of fullness', whilst maintaining compliance...
July 22, 2016: BJU International
https://www.readbyqxmd.com/read/27437534/progressive-changes-in-detrusor-function-and-micturition-patterns-with-chroinc-bladder-ischemia
#13
Zuohui Zhao, Roya Azad, Jing-Hua Yang, Mike B Siroky, Kazem M Azadzoi
PURPOSE: Lower urinary tract symptoms (LUTS) are bothersome constellation of voiding symptoms in men and women as they age. Multiple factors and comorbidities are attributed to this problem but underlying mechanisms of nonobstructive nonneurogenic detrusor overactivity, detrusor underactivity and LUTS remain largely unknown. Our goal was to characterize detrusor function and voiding patterns in relation to muscarinic receptors expression, nerve fiber density, and neural ultrastructure in chronic bladder ischemia...
July 2016: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/27436428/urothelial-barrier-deficits-suburothelial-inflammation-and-altered-sensory-protein-expression-in-detrusor-underactivity
#14
Yuan-Hong Jiang, Hann-Chorng Kuo
PURPOSE: The pathophysiology of detrusor underactivity remains unclear and impaired bladder afferent function is considered one of the important etiologies. We investigated urothelial barrier deficits, suburothelial inflammation and sensory proteins expressed in the bladder mucosa of patients with detrusor underactivity. MATERIALS AND METHODS: Bladder mucosa biopsies were performed in 34 patients with videourodynamic proven detrusor underactivity as the study group and in 10 women with stress urinary incontinence as controls...
July 17, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27366877/role-of-bladder-dysfunction-in-men-with-lower-urinary-tract-symptoms-refractory-to-alpha-blocker-therapy-a-video-urodynamic-analysis
#15
Yuan-Hong Jiang, Chun-Hou Liao, Hann-Chorng Kuo
OBJECTIVES: Lower urinary tract symptoms (LUTS) in men result from a complex interplay of pathophysiology, including bladder and bladder outlet dysfunction. This study retrospectively analyzed bladder dysfunction in men with LUTS based on the results of video-urodynamic studies (VUDS). METHODS: Male patients (aged ≥40 years), with LUTS and an International Prostate Symptom Score of 8 or more, who were refractory to alpha-blocker treatment were retrospectively recruited and evaluated with VUDS and total prostate volume (TPV)...
July 1, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27302797/re-the-overactive-bladder-progression-to-underactive-bladder-hypothesis
#16
Alan J Wein
No abstract text is available yet for this article.
April 2016: Journal of Urology
https://www.readbyqxmd.com/read/27222131/a-ventral-root-avulsion-injury-model-for-neurogenic-underactive-bladder-studies
#17
REVIEW
Huiyi H Chang, Leif A Havton
Detrusor underactivity (DU) is defined as a contraction of reduced strength and/or duration during bladder emptying and results in incomplete and prolonged bladder emptying. The clinical diagnosis of DU is challenging when present alone or in association with other bladder conditions such as detrusor overactivity, urinary retention, detrusor hyperactivity with impaired contractility, aging, and neurological injuries. Several etiologies may be responsible for DU or the development of an underactive bladder (UAB), but the pathobiology of DU or UAB is not well understood...
November 2016: Experimental Neurology
https://www.readbyqxmd.com/read/27191085/re-the-underactive-bladder-a-new-clinical-concept
#18
Alan J Wein
No abstract text is available yet for this article.
June 2016: Journal of Urology
https://www.readbyqxmd.com/read/27175342/meningitis-retention-syndrome-a-case-report
#19
Gen Ishii, Kenichi Hata, Soichiro Aoki, Masayasu Suzuki, Takahiro Kimura, Shin Egawa
We report a case of meningitis-retention syndrome followed by urodynamic tests. A 48-year-old man was admitted to the hospital for an undiagnosed fever with headache and urinary retention. Aseptic meningitis was suspected according to cerebrospinal fluid analyses, and urodynamic test showed an underactive detrusor, leading to inadequate contraction of the bladder on voiding in spite of a normal sensation during bladder filling. Clean intermittent self-catheterization was required temporarily, but normal urinary voiding without the need for medication was restored in 2 weeks after discharge from the hospital, when urodynamic tests showed normal contractility of the bladder during voiding...
May 2016: Urology Case Reports
https://www.readbyqxmd.com/read/27134738/recent-advances-in-the-understanding-of-male-lower-urinary-tract-symptoms-luts
#20
REVIEW
Arman A Kahokehr, Peter J Gilling
In this review, we have looked at three important areas in understanding male lower urinary tract symptoms. These are improvement in terminology, detrusor underactivity, and nocturia. Benign prostatic hyperplasia leading to bladder outlet obstruction has been covered in a previous review.
2016: F1000Research
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