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JOURNAL ARTICLE
Joseph M Serino, E Bailey Terhune, Robert A Burnett, John D D Higgins, Joshua J Jacobs, Craig J Della Valle, Denis Nam
OBJECTIVES: The ideal timing for patients undergoing bilateral total knee arthroplasty (TKA) remains unknown. The purpose of this study was to compare 90-day outcomes between unilateral, simultaneous bilateral, and staged bilateral TKA. METHODS: The PearlDiver database was used to retrospectively identify 231,119 patients undergoing primary TKA during 2015-2020, of which 67,956 (29.4%) were bilateral. Bilateral TKA patients were divided into cohorts of simultaneous bilateral TKA and staged bilateral TKA at 1-14 days, 15-30 days, 31-90 days, and 91-365 days...
2024: Archives of Bone and Joint Surgery
#22
JOURNAL ARTICLE
Mohit D Gupta, Vishal Batra, Subrat Muduli, Girish Mp, Shekhar Kunal, Ankit Bansal, Ankur Gautam, Rajeev Kumar Malhotra, Dixit Goyal, Arman Qamar, Jamal Yusuf
BACKGROUND: Despite significant progress in primary prevention, rates of myocardial infarction (MI) in South Asian population is alarmingly high. OBJECTIVES: We sought to compare risk factor profiles and outcomes between individuals with ST-Segment Elevation Myocardial Infarction (STEMI) in young (<50 years) and old (≥50 years) age groups. METHODS: North India STEMI Registry (NORIN-STEMI) is a prospective observational registry of patients hospitalised with STEMI...
April 2, 2024: Indian Heart Journal
#23
JOURNAL ARTICLE
Risk Factors for Unexpected Admission Following Lumbar Spine Laminectomy: A National Database Study.
John M Tarazi, Petros Koutsogiannis, Emma K Humphrey, Nabil Z Khan, Michael Katsigiorgis, Gus Katsigiorgis, Randy M Cohn
Introduction Laminectomy is one of the most common orthopedic spine surgeries performed in the United States. Compared to other spine operations such as fusions, laminectomies in isolation are of lower morbidity. However, complications may arise that result in readmission to an inpatient healthcare facility. The purpose of this study is to identify the demographics and risk factors associated with unplanned 30-day readmission following a laminectomy. Methods The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried for patients who underwent a laminectomy procedure from 2015 to 2019 using CPT code 63030...
March 2024: Curēus
#24
JOURNAL ARTICLE
Navneet Agarwal, Mohammed Nadeem Shaikh, Anisha Banu, Paridhi Ahuja
BACKGROUND: Tobacco is consumed mainly as smoking or smokeless tobacco [SLT]. "Smokeless tobacco" (SLT) term is used for the consumption of tobacco mixed with other constituents in form of chewing, spitting and dipping. Consumers of smokeless tobacco chew the products and spit out the juice that builds up in oral cavity which leads to various malignant and pre malignant lesions of oral cavity. METHODS: Descriptive observational study was conducted in the city of Jodhpur through department of ENT, Head & Neck Surgery, Dr...
April 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
#25
JOURNAL ARTICLE
Boonsub Sakboonyarat, Jaturon Poovieng, Ram Rangsin
BACKGROUND: Left ventricular hypertrophy (LVH) strongly predicts cardiovascular diseases (CVD) and death. One-fourth of Thai adults suffer from hypertension. Nevertheless, the information on LVH among Thai patients with hypertension is not well characterized. We aimed to identify the prevalence and factors associated with electrocardiographic LVH (ECG-LVH) among patients with hypertension in Thailand. METHODS: The present study obtained the dataset from the Thailand Diabetes Mellitus/Hypertension study, which included hypertension patients aged 20 years and older receiving continuous care at outpatient clinics in hospitals nationwide in 2011-2015 and 2018...
April 1, 2024: Clinical Hypertension
#26
JOURNAL ARTICLE
Giorgio Colangelo, Marc Ribo, Estefanía Montiel, Didier Dominguez, Marta Olivé-Gadea, Marian Muchada, Álvaro Garcia-Tornel, Manuel Requena, Jorge Pagola, Jesús Juega, David Rodriguez-Luna, Noelia Rodriguez-Villatoro, Federica Rizzo, Belén Taborda, Carlos A Molina, Marta Rubiera
BACKGROUND: Predicting stroke recurrence for individual patients is difficult, but individualized prediction may improve stroke survivors' engagement in self-care. We developed PRERISK: a statistical and machine learning classifier to predict individual risk of stroke recurrence. METHODS: We analyzed clinical and socioeconomic data from a prospectively collected public health care-based data set of 41 975 patients admitted with stroke diagnosis in 88 public health centers over 6 years (2014-2020) in Catalonia-Spain...
March 28, 2024: Stroke; a Journal of Cerebral Circulation
#27
JOURNAL ARTICLE
Anne-Laure Hamel, Léo Delbos, Pierre-André Natella, Thomas Radulesco, Mihaela Alexandru, Emmanuel Bartaire, Sophie Bartier, Gonda Benoite, Emilie Bequignon, Laurent Castillo, Florence Canouï-Poitrine, Florent Carsuzaa, Alain Corré, André Coste, Vincent Couloigner, Clémentine Daveau, Paul De Boissieu, Guillaume De Bonnecaze, Ludovic De Gabory, Christian Debry, Simon Deraedt, Xavier Dufour, Wissame El Bakkouri, Laurent Gilain, Stéphane Hans, Charlotte Hautefort, Ruben Hermann, Roger Jankowski, Candice La Croix, Jean-Baptiste Lecanu, Olivier Malard, Justin Michel, Yann Nguyen, Jerome Nevoux, Jean-François Papon, Vincent Patron, Marine Prigent, Virginie Pruliere-Escabasse, Marion Renaud, Cécile Rumeau, Dominique Salmon, Nicolas Saroul, Elie Serrano, Christine Nhung Tran Khai, Stéphane Tringali, Eric Truy, Clair Vandersteen, Benjamin Verillaud, Raphaël Veil, Maxime Fieux
BACKGROUND: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient's medical management (outpa-tient care, standard hospital admission, and ICU admission). METHODS: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing...
February 22, 2024: Life
#28
REVIEW
Ludovico Lucenti, Gianluca Testa, Alessia Caldaci, Fabio Sammartino, Calogero Cicio, Martina Ilardo, Marco Sapienza, Vito Pavone
Periprosthetic joint infection (PJI) poses a challenging complication for many patients undergoing arthroplasty, and the literature identifies numerous risk factors. A comprehensive understanding of the primary risk and protective factors for PJI is valuable for surgeons. This article aims to compile and summarize the key risk factors for PJI documented in the literature. Some risk factors are related to the nutritional status of patients, with obesity, weight loss, hypovitaminosis, and malnutrition being frequently reported...
March 15, 2024: Healthcare (Basel, Switzerland)
#29
REVIEW
Atefeh Afsar, Li Zhang
Mitochondria are the powerhouse of the cell. Mitochondria serve as the major source of oxidative stress. Impaired mitochondria produce less adenosine triphosphate (ATP) but generate more reactive oxygen species (ROS), which could be a major factor in the oxidative imbalance observed in Alzheimer's disease (AD). Well-balanced mitochondrial respiration is important for the proper functioning of cells and human health. Indeed, recent research has shown that elevated mitochondrial respiration underlies the development and therapy resistance of many types of cancer, whereas diminished mitochondrial respiration is linked to the pathogenesis of AD...
March 14, 2024: Biology
#30
JOURNAL ARTICLE
John Robins, Irem Patel, Ann McNeill, John Moxham, Arran Woodhouse, Gareth Absalom, Buljana Shehu, Geraldine Bruce, Amy Dewar, Alanna Molloy, Stephanie Duckworth Porras, Michael Waring, Andrew Stock, Debbie Robson
BACKGROUND: The National Health Service in England aims to implement tobacco dependency treatment services in all hospitals by 2024. We aimed to assess the uptake of a new service, adapted from the Ottawa Model of Smoking Cessation, and its impact on 6-month quit rates and readmission or death at 1-year follow-up. METHODS: We conducted a pragmatic service evaluation of a tobacco dependency service implemented among 2067 patients who smoked who were admitted to 2 acute hospitals in London, England, over a 12-month period from July 2020...
March 25, 2024: BMC Medicine
#31
JOURNAL ARTICLE
William R Lorenz, Alexis M Holland, Brittany S Mead, Gregory T Scarola, Vedra A Augenstein, B Todd Heniford
An analysis of ACS-NSQIP open ventral hernia repair (OVHR) data (2017-2019) was performed. Respiratory failure (RF) occurred in 643 patients (1%) and not in 63,213 (99%) (nRF). Respiratory failure patients were older (63.7 vs 57 years, P < .001) and more comorbid: insulin-dependent diabetes (14.7% vs 5.8%, P < .001), COPD (19.4% vs 5.2%, P < .001), BMI (36.0 vs 32.8, P < .001), and current tobacco use (24.9% vs 17.6%, P < .001). Respiratory failure patients had greater ASA scores (ASA 3: 63...
March 24, 2024: American Surgeon
#32
JOURNAL ARTICLE
Noé Carème Manfouo Fouotsa, Ruth Ndjaboue, Gerard Ngueta
OBJECTIVES: Among US adults aged 20 + years in the USA with previously diagnosed type 2 diabetes mellitus (T2DM), we aimed to estimate the prevalence of early-onset T2DM (onset at age < 50.5 years) and to test associations between early-onset T2DM and race/ethnicity, and other hypothesized predictors. METHODS: We pooled data from the annual National Health and Nutrition Examination Surveys (NHANES) over the years 2001 through 2018...
March 21, 2024: Journal of Racial and Ethnic Health Disparities
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JOURNAL ARTICLE
Rishav Sinha, Dhairya Nanavaty, Arij Azhar, Pradeep Devarakonda, Sohrab Singh, Rupa Garikipati, Ankushi Sanghvi, Suganya Manoharan, Gaurav Parhar, Kiran Zaman, Cesar Ayala-Rodriguez, Viswanath Vasudevan, Sarath Reddy, Louis Gerolemou
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a relatively rare disease with increasing incidence trends. Cardiovascular disease is a significant complication in IPF patients due to the role of common proatherogenic immune mediators. The prevalence of coronary artery disease (CAD) in IPF and the association between these distinct pathologies with overlapping pathophysiology remain less studied. RESEARCH QUESTION: We hypothesised that IPF is an independent risk factor for CAD...
March 20, 2024: BMJ Open Respiratory Research
#34
JOURNAL ARTICLE
Xiaoya Huang, Qiang Ye, Zhenguo Zhu, Yanyan Chen, Niange Xia, Rongrong Chen, Wujun Geng, Zusen Ye
The rate of early neurological deterioration (END) differs in different subtypes of ischaemic stroke. Previous studies showed PLCL2 gene is a novel susceptibility locus for the occurrence of atherosclerosis and thrombotic events. The objective of this research is to examine the efficacy that PLCL2 may have on the risk of END in large artery atherosclerotic (LAA) stroke. Tagged single nucleotide polymorphisms (SNPs) were identified by a strategy of fine-mapping. The genotyping of the selected SNPs was performed by SNPscan...
March 16, 2024: Brain Research
#35
JOURNAL ARTICLE
Tyler Roberts, Varun Sambhariya, Colin Ly, Alison Ho, William F Pientka Ii
Background: We aim to evaluate the impact of advanced age and sex on postoperative complications and radiographic outcomes after open reduction with internal fixation of distal radius fractures (DRF). Methods: We conducted a retrospective chart review, including all patients who underwent open reduction with internal fixation of a DRF between 2012 and 2018 at a single level 1 trauma centre. We recorded patient age, sex, fracture classification (Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association [AO/OTA]), time from injury to surgical date, surgical duration, diabetes status, tobacco use, illicit drug use, history of osteoporosis, use of adjuvants, fixation type, postoperative radiographic restoration of normal parameters and early complications including loss of reduction within 30 days postoperatively...
March 15, 2024: Journal of Hand Surgery Asian-Pacific Volume
#36
JOURNAL ARTICLE
Intra-Operative Pedal Pressure Changes Offers Another Quantitative Assessment For Revascularization.
Michael Rouse, Qingwen Kawaji, Darshan Randhawa, Jason Chin, Raghuveer Vallabhaneni, Jason Crowner
INTRODUCTION: Lower extremity angiography is one of the most prevalent vascular procedures performed, generally via the contralateral common femoral artery. The use of retrograde pedal artery access to perform angiography has long been reserved as a "bail-out" technique to help cross chronic total occlusions that were not amenable from an antegrade approach. Recently, there has been reports and discussion involving increased utilization of pedal access for primary revascularization. The purpose of this study is to describe the outcomes of pedal access as a primary approach and to propose a novel evaluation of distal perfusion changes associated with interventions using direct pressure measurements...
March 14, 2024: Annals of Vascular Surgery
#37
JOURNAL ARTICLE
E Sornay-Rendu, F Duboeuf, R D Chapurlat
Most postmenopausal women who sustain fragility fracture (Fx) have their areal bone mineral density (aBMD) above the osteoporosis threshold. A sizeable proportion of them have normal aBMD. The aim of this study was to prospectively investigate the association of fragility Fx with bone microarchitecture (MA) assessed by high resolution peripheral computed tomography (HR-pQCT) in postmenopausal women without low BMD. At the 14th annual follow-up of the OFELY study, we have measured bone MA at the distal radius and tibia with HR-pQCT in addition to areal BMD with DXA, in 586 postmenopausal women...
March 14, 2024: Bone
#38
JOURNAL ARTICLE
Haoran Zhou, Tianshu Li, Jie Li, Dongdong Zheng, Jie Yang, Xin Zhuang
BACKGROUND: There is growing evidence that antioxidant-rich diets may prevent hyperlipidemia. However, the relationship between the Composite Dietary Antioxidant Index (CDAI) and hyperlipidemia is unclear. The CDAI is a composite score reflecting the antioxidant content of an individual's diet, and this study aimed to investigate the relationship between CDAI and hyperlipidemia. METHODS: The study used the 2003-2018 National Health and Nutrition Examination Survey (NHANES) database for cross-sectional analyses and included 27,626 participants aged 20 years and older...
2024: Frontiers in Nutrition
#39
JOURNAL ARTICLE
Joseph Grech, Ian James Norman, Roberta Sammut
BACKGROUND: The literature indicates that individuals with diabetes do not easily adopt smoking cessation interventions. Given that the success of such interventions depends on patient involvement and attitudes, assessing intervention acceptability, including patient satisfaction and perceived usefulness, is crucial before implementing a smoking cessation intervention. This paper reports the preliminary validation of the satisfaction and perceived usefulness questionnaires for evaluating smoking cessation interventions among individuals with diabetes...
June 2024: Public health in practice
#40
JOURNAL ARTICLE
Courtney Kay Pfeuti, Annetta Madsen, Elizabeth Habermann, Amy Glasgow, John A Occhino
IMPORTANCE: Racial and ethnic disparities exist in urogynecologic surgery; however, literature identifying specific disparities after sling operations for stress incontinence are limited. OBJECTIVE: The objective of this study was to evaluate racial and ethnic disparities in surgical complications within 30 days of midurethral sling operations. STUDY DESIGN: This retrospective cohort study identified women who underwent an isolated midurethral sling operation between 2014 and 2021 using the American College of Surgeons National Surgical Quality Improvement Program database...
March 1, 2024: Urogynecology (Phila)
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