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https://www.readbyqxmd.com/read/28098043/-the-effects-of-smoking-on-health-growth-of-knowledge-reveals-even-grimmer-picture
#1
J P Mackenbach, R A M Damhuis, J V Been
- In this article we give a short overview of new insights into the effects of smoking on health, both on smokers themselves and on those who are exposed to other people's tobacco smoke.- The number of diseases and conditions that are known to be caused by active smoking has now risen to over thirty.- The risk of premature death is not, as previously thought, twice as high in smokers as in non-smokers, but actually three times as high.- Passive smoking too has been shown to have a whole range of negative effects on health...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28095732/an-online-survey-of-tobacco-smoking-cessation-associated-with-naturalistic-psychedelic-use
#2
Matthew W Johnson, Albert Garcia-Romeu, Patrick S Johnson, Roland R Griffiths
Data suggest psychedelics such as psilocybin and lysergic acid diethylamide (LSD) may hold therapeutic potential in the treatment of addictions, including tobacco dependence. This retrospective cross-sectional anonymous online survey characterized 358 individuals (52 females) who reported having quit or reduced smoking after ingesting a psychedelic in a non-laboratory setting ⩾1 year ago. On average, participants smoked 14 cigarettes/day for 8 years, and had five previous quit attempts before their psychedelic experience...
January 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28095281/nurses-attitudes-toward-intervening-with-smokers-their-knowledge-opinion-and-e-learning-impact
#3
Eva Králíková, Vladislava Felbrová, Stanislava Kulovaná, Kateřina Malá, Iveta Nohavová, Eva Roubíčková, Alexandra Pánková, Stella A Bialous, Marjorie J Wells, Jenny Brook, Linda Sarna
BACKGROUND: Numbering about 90,000, nurses represent the largest group of health care providers in the Czech Republic. Therefore, nurses can make a significant impact in the treatment of tobacco dependence, particularly in applying brief interventions to smokers. METHODS: During 2014, 279 nurses from the Czech Republic participated in an e-learning education programme consisting of two Webcasts with additional web-based resources about smoking cessation in relation to health and treatment options in daily clinical practice, particularly regarding brief intervention methods...
December 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28092943/context-matters-contribution-of-specific-dna-adducts-to-the-genotoxic-properties-of-the-tobacco-specific-nitrosamine-nnk
#4
Lisa A Peterson
The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a potent pulmonary carcinogen in laboratory animals. It is classified as a Group 1 human carcinogen by the International Agency for Cancer Research. NNK is bioactivated upon cytochrome P450 catalyzed hydroxylation of the carbon atoms adjacent to the nitrosamino group to both methylating and pyridyloxobutylating agents. Both pathways generate a spectrum of DNA damage that contributes to the overall mutagenic and toxic properties of this compound...
January 17, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28088742/patterns-of-drug-use-and-hiv-infection-among-adults-in-a-nationally-representative-sample
#5
Stephanie Shiau, Stephen M Arpadi, Michael T Yin, Silvia S Martins
BACKGROUND: Little is known about drug use patterns among people living with HIV in comparison to an uninfected group in the general population. The aim of this study was to investigate the association between legal and illegal drug use and HIV infection in a nationally representative sample of adults in the United States. METHODS: Public use data files (2005-2014) from the National Survey on Drug Use and Health (NSDUH) were used. Respondents were asked whether a medical professional had ever told them that they had HIV/AIDS...
January 7, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28077940/physician-tobacco-screening-and-advice-to-quit-among-u-s-adolescents-national-survey-on-drug-use-and-health-2013
#6
Lauren Collins, Sabrina L Smiley, Rakiya A Moore, Amanda L Graham, Andrea C Villanti
BACKGROUND: Initiating tobacco use in adolescence increases the risk of nicotine dependence and continued smoking. Physician screening for tobacco use increases the odds of physicians intervening with patients who smoke; However, without appropriate follow-through by the physician, screening for tobacco use is not enough to significantly increase cessation rates. Given the critical phase of development adolescence poses in tobacco use and evidence that physician intervention improves adult cessation efforts, we sought to examine physician tobacco use screening and advice to quit among adolescents (12-17 years)...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28077504/influence-of-history-of-cannabis-smoking-in-selected-donors-on-the-outcomes-of-lung-transplantation
#7
Prashant N Mohite, Mohamed Zeriouh, Diana G Sáez, Aron-Frederik Popov, Anton Sabashnikov, Bartlomiej Zych, Ashok Padukone, Levente Fazekas, Olga Ananiadou, Fabio De Robertis, Simona Soresi, Anna Reed, Martin Carby, André R Simon
OBJECTIVES: Cannabis is the most commonly abused illicit drug and the smokers are at the risk of lung infections, bullous emphysema and lung cancer. However, no evidence about the outcomes of lung transplantation (LTx) utilizing the lungs from such donors is available in the literature. METHODS: We retrospectively analysed lung 'organ offers' and LTx at our centre between January 2007 and November 2013. The outcomes of LTx utilizing lungs from donors with a history of cannabis smoking were compared with the outcomes of those with no such history using unadjusted model as well as propensity score matching...
January 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28077163/the-efficacy-of-varenicline-in-achieving-abstinence-among-waterpipe-tobacco-smokers-study-protocol-for-a-randomized-controlled-trial
#8
Raana Zahid, Omara Dogar, Sonia Mansoor, Amina Khan, Mona Kanaan, Mohammed Jawad, Jasjit S Ahluwalia, Kamran Siddiqi
BACKGROUND: Waterpipe tobacco smoking has increased among youth across the globe including in the US, and it continues as a common and traditional form of smoking tobacco in Pakistan. A range of behavioral and pharmacological therapies are available to support people in quitting cigarette smoking; however, little evidence exists for the efficacy of these therapies in achieving abstinence among waterpipe tobacco smokers. The objective of this study is to assess the efficacy of varenicline when added to behavioral support for waterpipe tobacco smoking cessation, by measuring biochemically validated continuous abstinence in waterpipe tobacco smokers...
January 11, 2017: Trials
https://www.readbyqxmd.com/read/28070179/prevalence-and-factors-that-influence-smokeless-tobacco-use-among-adults-in-pastoralist-communities-of-borena-zone-ethiopia-mixed-method-study
#9
Edao Sinba Etu, Desta Hiko Gemeda, Mamusha Aman Hussen
BACKGROUND: Deaths due to tobacco consumption are on the rise, from 5.4 million in 2005 to 6.4 million in 2015 and 8.3 million in 2030 of which more than 80% will be in developing countries. Smokeless tobacco use is a significant health risk and cause of disease. Over 300 million people use smokeless tobacco worldwide. More than 250 million adult smokeless tobacco users are in low- and middle-income countries, the total burden of smokeless tobacco use is likely to be substantial. In Ethiopia, nationally representative data on the smokeless tobacco use is not available...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28069549/snps-within-chrna5-a3-b4-and-cyp2a6-b6-are-associated-with-smoking-dependence-but-not-with-tobacco-dependence-treatment-outcomes-in-the-czech-population
#10
J A Hubacek, A Pankova, L Stepankova, K Zvolska, V Adamkova, V Lanska, E Kralikova
PURPOSE: Tobacco/nicotine dependence has a significant heritable component. Genome-wide association studies have associated the single nucleotide polymorphisms (SNPs) rs578776, rs16969968, rs6474412, rs3733829 and rs4105144 with nicotine dependence in Western European populations. We examined whether these SNPs influence nicotine dependence and successful treatment of tobacco dependence in the Czech middle-European population. MATERIALS AND METHODS: Variants were analysed by PCR-RFLP or by TaqMan assay in 807 adult heavy tobacco-dependent smokers - patients of the Centre for Treatment of Tobacco Dependence (Prague) as well as 1,362 self-reported non-smokers...
January 6, 2017: Gene
https://www.readbyqxmd.com/read/28064202/trends-in-and-characteristics-of-marijuana-and-menthol-cigarette-use-among-current-cigarette-smokers-2005-2014
#11
Gillian L Schauer, Erica N Peters, Zachary Rosenberry, Hyoshin Kim
BACKGROUND: Given increasing co-marijuana and tobacco use in the U.S., this study aimed to explore the overlap between menthol cigarette use (MCU) and marijuana. METHODS: Data came from past month U.S. cigarette smokers 12 years and older responding to the National Survey on Drug Use and Health between 2005 and 2014 (N= 51,500). Prevalence, demographics and substance use characteristics from 2013-14 were assessed across four groups, based on past month marijuana and tobacco use: cigarette smokers with marijuana and MCU, with marijuana but no MCU, with no marijuana but MCU, and with use of neither...
January 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28064178/linking-photosynthesis-and-leaf-n-allocation-under-future-elevated-co2-and-climate-warming-in-eucalyptus-globulus
#12
Robert E Sharwood, Kristine Y Crous, Spencer M Whitney, David S Ellsworth, Oula Ghannoum
Leaf-level photosynthetic processes and their environmental dependencies are critical for estimating CO2 uptake from the atmosphere. These estimates use biochemical-based models of photosynthesis that require accurate Rubisco kinetics. We investigated the effects of canopy position, elevated atmospheric CO2 [eC; ambient CO2 (aC)+240 ppm] and elevated air temperature (eT; ambient temperature (aT)+3 °C) on Rubisco content and activity together with the relationship between leaf N and V cmax (maximal Rubisco carboxylation rate) of 7 m tall, soil-grown Eucalyptus globulus trees...
January 7, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28053190/phobf1-a-petunia-ocs-element-binding-factor-plays-an-important-role-in-antiviral-rna-silencing
#13
Daoyang Sun, Shaohua Li, Lixin Niu, Michael S Reid, Yanlong Zhang, Cai-Zhong Jiang
Virus-induced gene silencing (VIGS) is a common reverse genetics strategy for characterizing the function of genes in plants. The detailed mechanism governing RNA silencing efficiency triggered by viruses is largely unclear. Here, we reveal that a petunia (Petunia hybrida) ocs element binding factor, PhOBF1, one of the basic leucine zipper (bZIP) transcription factors, was up-regulated by Tobacco rattle virus (TRV) infection. Simultaneous silencing of PhOBF1 and a reporter gene, phytoene desaturase (PDS) or chalcone synthase (CHS), by TRV-based VIGS led to a failure of the development of leaf photobleaching or the white-corollas phenotype...
January 4, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28050337/race-ethnicity-and-intention-to-quit-cigarette-smoking
#14
Julia N Soulakova, Jinyu Li, Lisa J Crockett
The study examined racial/ethnic differences in smokers' intentions to quit smoking within the next 6 months. The sample included 20,693 current non-occasional smokers in the U.S. who responded to the 2010-2011 Tobacco Use Supplement to the Current Population Survey. The rates of intention to quit within 1 month were significantly higher for non-Hispanic (NH) Black (21%; OR = 1.44, CI = 1.24-1.67) and Hispanic (21%; OR = 1.42, CI = 1.20-1.68) than for the NH Whites (NHW, 15%). The rates of intention to quit within 6 months were significantly higher for NH Blacks (46%; OR = 1...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28042597/the-effect-of-comparatively-framed-versus-similarity-framed-e-cigarette-and-snus-print-ads-on-young-adults-ad-and-product-perceptions
#15
Smita C Banerjee, Kathryn Greene, Yuelin Li, Jamie S Ostroff
OBJECTIVES: This study examined the effects of comparative-framing [C-F; ads highlighting differences between the advertised product and conventional cigarettes and/or smokeless tobacco products] versus similarity-framing (S-F; ads highlighting congruence with conventional cigarettes and/or smokeless tobacco products) in e-cigarette and snus ads on young adult smokers' and non-smokers' ad- and product-related perceptions. METHODS: One thousand fifty one (1,051) young adults (18-24 years; 76% women; 50% smokers) from existing consumer panels were recruited in a within-subjects quasi-experiment...
July 2016: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/28039401/smoking-correlates-with-increased-cytoskeletal-protein-related-coding-region-mutations-in-the-lung-and-head-and-neck-datasets-of-the-cancer-genome-atlas
#16
John M Yavorski, George Blanck
Cancer from smoking tobacco is considered dependent on mutagens, but significant molecular aspects of smoking-specific, cancer development remain unknown. We defined sets of coding regions for oncoproteins, tumor suppressor proteins, and cytoskeletal-related proteins that were compared between nonsmokers and smokers, for mutation occurrences, in the lung adenocarcinoma (LUAD), head and neck squamous carcinoma (HNSC), bladder carcinoma (BLCA), and pancreatic adenocarcinoma ( PAAD) datasets from the cancer genome atlas (TCGA)...
December 2016: Physiological Reports
https://www.readbyqxmd.com/read/28034999/perceptions-of-snus-among-us-adult-smokers-given-free-product
#17
Ellen Meier, Jessica L Burris, Amy Wahlquist, Elizabeth Garrett-Mayer, Kevin M Gray, Anthony J Alberg, K Michael Cummings, Matthew J Carpenter
INTRODUCTION: Snus uptake is nominal among US smokers. This longitudinal study examines a) perceptions of snus among US smokers given free snus for six weeks and b) a method for assessment of an alternative tobacco product at the population level. METHODS: Adult smokers (n=543; 69.2% female; Mage=49.3 years), uninterested in quitting, received free snus for ad libitum use. Based on their snus use during a 6-week sampling period, participants included: 1) never users (18...
December 29, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28029133/cinnamaldehyde-ameliorates-cadmium-inhibited-root-elongation-in-tobacco-seedlings-via-decreasing-endogenous-hydrogen-sulfide-production
#18
Xie-Feng Ye, Yanfeng Xue, Tianxiao Ling, Yong Wang, Xiao-Na Yu, Changxin Cheng, Guosheng Feng, Liangbin Hu, Zhiqi Shi, Jian Chen
Cinnamaldehyde (CA) is natural plant-derived compound that has been highly appreciated for its medicinal properties. However, little information is known about the regulation of plant intrinsic physiology by CA. To address these gaps, physiological, histochemical, and biochemical approaches were applied to investigate CA-facilitated cadmium (Cd) tolerance in the roots of tobacco (Nicotiana tabacum) seedlings. Treatment with CdCl₂ at 20 μM for 72 h resulted in the significant decrease in root elongation by 40...
December 24, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28025590/nicotinic-acetylcholine-receptors-as-targets-for-tobacco-cessation-therapeutics-cutting-edge-methodologies-to-understand-receptor-assembly-and-trafficking
#19
Ashley M Fox-Loe, Linda P Dwoskin, Christopher I Richards
Tobacco dependence is a chronic relapsing disorder and nicotine, the primary alkaloid in tobacco, acts at nicotinic receptors to stimulate dopamine release in brain, which is responsible for the reinforcing properties of nicotine, leading to addiction. Although the majority of tobacco users express the desire to quit, only a small percentage of those attempting to quit are successful using the currently available pharmacotherapies. Nicotine upregulates the number of specific nicotinic receptors on the neuronal cell surface...
2016: Neuromethods
https://www.readbyqxmd.com/read/28025588/exporting-an-inherently-harmful-product-the-marketing-of-virginia-slims-cigarettes-in-the-united-states-japan-and-korea
#20
Timothy Dewhirst, Wonkyong B Lee, Geoffrey T Fong, Pamela M Ling
Ethical issues surrounding the marketing and trade of controversial products such as tobacco require a better understanding. Virginia Slims, an exclusively women's cigarette brand first launched in 1968 in the USA, was introduced during the mid 1980s to major Asian markets, such as Japan and Korea, dominated by male smokers. By reviewing internal corporate documents, made public from litigation, we examine the marketing strategies used by Philip Morris as they entered new markets such as Japan and Korea and consider the extent that the company attempted to appeal to women in markets where comparatively few women were smokers...
November 2016: Journal of Business Ethics: JBE
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