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https://www.readbyqxmd.com/read/28820734/characteristics-reasons-behavior-and-knowledge-towards-waterpipe-smoking-in-saudi-arabia
#1
Elluru Venkatesh, Mohammad Yousef Al Jemal, Abdullah Saleh Al Samani
Background The present scenario shows that waterpipe smoking, one of tobacco smoking methods, the practice off which dates back at least 400 year is appealing to the youth. Waterpipe tobacco smoking is frequently linked with nations of the Eastern Mediterranean Region (EMR) comprising Egypt, Kuwait, Lebanon and Syria. The present study shows the socio-demographic characteristics, behavior and knowledge of youth towards waterpipe smoking. Recognizing these features may help emphasize intervention methods. Methods A self-administered questionnaire was used to collect the data about waterpipe smoking comprising sociodemographic, behavior, reasons and knowledge from 230 university students...
August 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28818753/benzoylsalicylic-acid-derivatives-as-defense-activators-in-tobacco-and-arabidopsis
#2
Samuel Kamatham, Reddanna Pallu, Anil Kumar Pasupulati, Surya Satyanarayana Singh, Padmaja Gudipalli
Systemic acquired resistance (SAR) is a long lasting inducible whole plant immunity often induced by either pathogens or chemical elicitors. Salicylic acid (SA) is a known SAR signal against a broad spectrum of pathogens in plants. In a recent study, we have reported that benzoylsalicylic acid (BzSA) is a SAR inducer in tobacco and Arabidopsis plants. Here, we have synthesized BzSA derivatives using SA and benzoyl chlorides of various moieties as substrates. The chemical structures of BzSA derivatives were elucidated using Infrared spectroscopy (IR), Nuclear magnetic spectroscopy (NMR) and High-resolution mass spectrometer (HRMS) analysis...
August 14, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28818685/ethyl-carbamate-induces-cell-death-through-its-effects-on-multiple-metabolic-pathways
#3
Huichang Liu, Bo Cui, Yi Xu, Chaoyang Hu, Ying Liu, Guorun Qu, Dawei Li, Yongning Wu, Dabing Zhang, Sheng Quan, Jianxin Shi
Ethyl carbamate (EC), a multisite carcinogenic chemical causing tumors in various animal species, is probably carcinogenic to humans. However, information about the possible carcinogenic and toxicological effects of EC in humans is quite limited. Because EC is found in many dietary foods (such as fermented foods) and tobacco and its products, and exposure of humans to EC often occurs inevitably, its toxicological effects in humans need to be studied. This study was conducted to understand the metabolomic and transcriptomic changes in human hepatocellular carcinoma cells (HepG2) exposed to 100 mM EC for short term (4 h) and long term (12 h) period, respectively...
August 14, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28818418/case-finding-for-persistent-airway-obstruction-in-farmers-a-questionnaire-with-optimal-diagnosis-criteria
#4
Alicia Guillien, Thibaud E Soumagne, Marc Puyraveau, Patrick Berger, Stéphanie L Guillot, Fabrice Rannou, Stéphane Jouneau, Frédéric J Mauny, Jean-Jacques Laplante, Jean-Charles Dalphin, Bruno Degano
INTRODUCTION: Appropriate identification of subjects who are candidates for spirometry through case-finding questionnaires may help solve the problem of chronic obstructive pulmonary disease misdiagnosis. The performance of case-finding questionnaires depends at least partially on the characteristics of the population used for their development. The use of an accurate threshold for the forced expiratory volume in 1 second / forced vital capacity ratio to define persistent airway obstruction is also vital in ascertaining chronic obstructive pulmonary disease...
August 14, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28818082/comparing-chronic-condition-rates-using-icd-9-and-icd-10-in-va-patients-fy2014-2016
#5
Jean Yoon, Adam Chow
BACKGROUND: Management of patients with chronic conditions relies on accurate measurement. It is unknown how transition to the ICD-10 coding system affected reporting of chronic condition rates over time. We measured chronic condition rates 2 years before and 1 year after the transition to ICD-10 to examine changes in prevalence rates and potential measurement issues in the Veterans Affairs (VA) health care system. METHODS: We developed definitions for 34 chronic conditions using ICD-9 and ICD-10 codes and compared the prevalence rates of these conditions from FY2014 to 2016 in a 20% random sample (1...
August 17, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28817334/community-health-worker-support-for-disadvantaged-patients-with-multiple-chronic-diseases-a-randomized-clinical-trial
#6
Shreya Kangovi, Nandita Mitra, David Grande, Hairong Huo, Robyn A Smith, Judith A Long
OBJECTIVES: To determine whether a community health worker (CHW) intervention improved outcomes in a low-income population with multiple chronic conditions. METHODS: We conducted a single-blind, randomized clinical trial in Philadelphia, Pennsylvania (2013-2014). Participants (n = 302) were high-poverty neighborhood residents, uninsured or publicly insured, and diagnosed with 2 or more chronic diseases (diabetes, obesity, tobacco dependence, hypertension). All patients set a disease-management goal...
August 17, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28814803/the-bhlh-transcription-factor-cgbhlh001-is-a-potential-interaction-partner-of-cdpk-in-halophyte-chenopodium-glaucum
#7
Juan Wang, Gang Cheng, Cui Wang, Zhuanzhuan He, Xinxin Lan, Shiyue Zhang, Haiyan Lan
Plants have evolved different abilities to adapt to the ever-fluctuating environments for sessility. Calcium-dependent protein kinase (CDPK) is believed to play a pivotal role in abiotic stress signaling. So far, study on the specific substrates that CDPK recognized in response to adversity is limited. In the present study, we revealed a potential interaction between CDPK and a bHLH transcription factor under salt stress in Chenopodium glaucum. First, we identified a CgCDPK, which was up-regulated under salt and drought stress; then by Y2H screening, CgCDPK was detected to be involved in interaction with a bHLH TF (named as CgbHLH001), which also positively respond to salt and drought stress...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810158/a-typology-of-vaping-identifying-differing-beliefs-motivations-for-use-identity-and-political-interest-amongst-e-cigarette-users
#8
Hannah Farrimond
BACKGROUND: The aim of this study was to identify and differentiate socially shared accounts of e-cigarette use (vaping) using Q-methodology, combining factor analysis with qualitative comments. METHODS: Seventy statements on e-cigarettes, drawn from media, academic and online discussions, were sorted by participants along a continuum of agreement/disagreement, commenting on strongly ranked items. Each participant thus created their own 'account' of their vaping...
August 12, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28806908/changing-the-default-for-tobacco-cessation-treatment-in-an-inpatient-setting-study-protocol-of-a-randomized-controlled-trial
#9
Babalola Faseru, Edward F Ellerbeck, Delwyn Catley, Byron J Gajewski, Taneisha S Scheuermann, Theresa I Shireman, Laura M Mussulman, Niaman Nazir, Terry Bush, Kimber P Richter
BACKGROUND: Most health care providers do not treat tobacco dependence routinely. This may in part be due to the treatment "default." Current treatment guidelines recommend that providers (1) ask patients if they are willing to quit and (2) provide cessation-focused medications and counseling only to smokers who state that they are willing to quit. The default is that patients have to "opt in" to receive cessation assistance: providers ask smokers if they are willing to quit, and only offer medications and cessation support to those who say "yes...
August 14, 2017: Trials
https://www.readbyqxmd.com/read/28806372/exploring-rural-disparities-in-medical-diagnoses-among-veterans-with-transgender-related-diagnoses-utilizing-veterans-health-administration-care
#10
Leigh A Bukowski, John Blosnich, Jillian C Shipherd, Michael R Kauth, George R Brown, Adam J Gordon
OBJECTIVES: Research shows transgender individuals experience pronounced health disparities compared with their nontransgender peers. Yet, there remains insufficient research about health differences within transgender populations. This study seeks to fill this gap by exploring how current urban/rural status is associated with lifetime diagnosis of mood disorder, alcohol dependence disorder, illicit drug abuse disorder, tobacco use, posttraumatic stress disorder, human immunodeficiency virus, and suicidal ideation or attempt among veterans with transgender-related diagnoses...
September 2017: Medical Care
https://www.readbyqxmd.com/read/28803919/therapy-related-clonal-hematopoiesis-in-patients-with-non-hematologic-cancers-is-common-and-associated-with-adverse-clinical-outcomes
#11
Catherine C Coombs, Ahmet Zehir, Sean M Devlin, Ashwin Kishtagari, Aijazuddin Syed, Philip Jonsson, David M Hyman, David B Solit, Mark E Robson, José Baselga, Maria E Arcila, Marc Ladanyi, Martin S Tallman, Ross L Levine, Michael F Berger
Clonal hematopoiesis (CH), as evidenced by recurrent somatic mutations in leukemia-associated genes, commonly occurs among aging human hematopoietic stem cells. We analyzed deep-coverage, targeted, next-generation sequencing (NGS) data of paired tumor and blood samples from 8,810 individuals to assess the frequency and clinical relevance of CH in patients with non-hematologic malignancies. We identified CH in 25% of cancer patients, with 4.5% harboring presumptive leukemia driver mutations (CH-PD). CH was associated with increased age, prior radiation therapy, and tobacco use...
August 9, 2017: Cell Stem Cell
https://www.readbyqxmd.com/read/28802872/smoking-and-binge-drinking-among-adolescents-ontario-canada-does-the-school-neighbourhood-matter
#12
Kristian Larsen, Teresa To, Hyacinth M Irving, Angela Boak, Hayley A Hamilton, Robert E Mann, Robert Schwartz, Guy E J Faulkner
This study examines whether access to alcohol and tobacco around the school relates to higher or lower odds of cigarette smoking and binge-drinking among Ontario high school students. The 2013 Ontario Student Drug Use and Health Survey provides data on self-reported smoking and drinking, individual covariates and subjective socio-economic status for 6142 students (grades 9-12) in Ontario, Canada. Locations of schools were geocoded and 1.6km network buffers defined the school neighbourhoods. Multi-level logistic regression examines individual and school neighbourhood factors with smoking and binge drinking as the dependent variable...
August 10, 2017: Health & Place
https://www.readbyqxmd.com/read/28801362/trends-in-cigarette-consumption-and-time-to-first-cigarette-on-awakening-from-2002-to-2015-in-the-usa-new-insights-into-the-ongoing-tobacco-epidemic
#13
Renee D Goodwin, Melanie M Wall, Misato Gbedemah, Mei-Chen Hu, Andrea H Weinberger, Sandro Galea, Michael J Zvolensky, Elizabeth Hangley, Deborah S Hasin
OBJECTIVE: The current study estimates trends in the number of cigarettes smoked per day (CPD) and percentage of smokers having their first CPD within 30 min of waking (time to first cigarette (TTFC)<30 min) among smokers from 2002 to 2015 in the USA overall, and adjusting for demographics. Trends in TTFC<30 min were also estimated by varying levels of cigarette consumption. METHODS: Data were drawn from the National Household Survey on Drug Use, an annual nationally representative cross-sectional study of the US population aged 12 and older (n=54 079-58 397 per year)...
August 10, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28799890/country-wide-distance-training-for-delivery-of-screening-and-brief-intervention-for-problematic-substance-use-a-pilot-evaluation-of-participant-experiences-and-patient-outcomes
#14
Ana Paula Leal Carneiro, Maria Lucia Oliveira Souza-Formigoni
BACKGROUND: In this study, we evaluated if the 120-hour distance-learning (DL) course SUPERA (an acronym in Portuguese meaning: System for detection of excessive use or dependence on psychoactive substances: brief Intervention, social reinsertion and follow-up) was an effective way to train health professionals and social workers to apply screening and brief intervention (SBI) for patients with substance use disorders. METHODS: In the first phase, 2,420 health professionals or social workers, who had completed the course, answered an online survey about their use of the SBI...
August 11, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28796297/transfer-of-tomato-immune-receptor-ve1-confers-ave1-dependent-verticillium-resistance-in-tobacco-and-cotton
#15
Yin Song, Linlin Liu, Yidong Wang, Dirk-Jan Valkenburg, Xianlong Zhang, Longfu Zhu, Bart P H J Thomma
Verticillium wilts caused by soil-borne fungal species of the Verticillium genus are economically important plant diseases that affect a wide range of host plants, and are notoriously difficult to combat. Perception of pathogen(-induced) ligands by plant immune receptors is a key component of plant innate immunity. In tomato, race-specific resistance to Verticillium wilt is governed by the cell surface-localized immune receptor Ve1 through recognition of the effector protein Ave1 that is secreted by race 1 strains of Verticillium spp...
August 10, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28795376/arabidopsis-prk6-interacts-specifically-with-atropgef8-12-and-induces-depolarized-growth-of-pollen-tubes-when-overexpressed
#16
Yuexuan Yu, Jiali Song, Xiaohui Tian, Haiwen Zhang, Legong Li, Huifen Zhu
The pollen receptor kinases (PRK) are critical regulators of pollen tube growth. The Arabidopsis genome encodes eight PRK genes, of which six are highly expressed in pollen tubes. The potential functions of AtPRK1 through AtPRK5, but not of AtPRK6, in pollen growth were analyzed in tobacco. Herein, AtPRK6 was cloned, and its function was identified. AtPRK6 was expressed specifically in pollen tubes. A yeast two-hybrid screen of AtPRK6 against 14 Arabidopsis Rop guanine nucleotide exchange factors (RopGEFs) showed that AtPRK6 interacted with AtRopGEF8 and AtRopGEF12...
August 8, 2017: Science China. Life Sciences
https://www.readbyqxmd.com/read/28792283/reasons-for-marijuana-and-tobacco-co-use-among-young-adults-a-mixed-methods-scale-development-study
#17
Carla J Berg, Jackelyn Payne, Lisa Henriksen, Patricia Cavazos-Rehg, Betelihem Getachew, Gillian L Schauer, Regine Haardörfer
BACKGROUND: Marijuana-tobacco co-use has increased recently, particularly in young adults. OBJECTIVES: We conducted a mixed-methods study to: (1) examine reasons for co-use; and (2) develop a scale assessing reasons for co-use among participants in a longitudinal cohort study of 3,418 students aged 18-25 from 7 Georgia colleges and universities. METHODS: Phone-based semi-structured interviews were conducted in Summer 2015 among 46 current (past 30-day, n = 26) or lifetime (n = 20) marijuana users...
August 9, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28783309/programming-self-assembly-of-tobacco-mosaic-virus-coat-proteins-at-pickering-emulsion-interfaces-for-nanorod-constructed-capsules
#18
Zhaocheng Wang, Sijia Gao, Xiangxiang Liu, Ye Tian, Man Wu, Zhongwei Niu
Pickering emulsion constructions on nanorods with high aspect ratio are a great challenge because of the geometry restrictions. On the basis of the theory that the stability of Pickering emulsion is highly dependent on the size and amphiphilicity of the nanoparticle at fluid interfaces, we report a novel strategy to fabricate long-time stable Pickering emulsion consisting of tobacco mosaic virus (TMV)-like nanorods through the programming self-assembly of TMV coat protein (TMVCP). The first step is the self-assembly of amphiphilic TMVCP at Pickering emulsion interfaces, and the second step is the in situ interfacial self-assembly of TMVCP into nanorods with increased particle size...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28777692/marijuana-use-and-driving-under-the-influence-among-young-adults-a-socioecological-perspective-on-risk-factors
#19
Carla J Berg, Carmen N Daniel, Milkie Vu, Jingjing Li, Kathleen Martin, Lana Le
BACKGROUND: Given increases in marijuana use and driving under the influence (DUI), it is critical to identify those at risk in order to inform intervention efforts. OBJECTIVES: We used a socioecological framework to examine correlates of level of marijuana use and DUI in the past month among young adult marijuana users. METHODS: We recruited 1567 participants aged 18-34 years via Facebook ads targeting tobacco and marijuana users in August 2014 to complete an online survey assessing marijuana use and DUI, as well as related multilevel factors...
August 4, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28777044/ectopic-expression-of-xylella-fastidiosa-rpff-conferring-production-of-diffusible-signal-factor-in-transgenic-tobacco-and-citrus-alters-pathogen-behavior-and-reduces-disease-severity
#20
Raquel Caserta, Reinaldo Rodrigues Souza-Neto, Marco Aurelio Takita, Steven Lindow, Alessandra De Souza
The pathogenicity of Xylella fastidiosa is associated with its ability to colonize the xylem of host plants. Expression of genes contributing to xylem colonization are suppressed, while those necessary for insect vector acquisition are increased, with increasing concentrations of diffusible signal factor (DSF) whose production is dependent on RpfF. We previously demonstrated that transgenic citrus plants ectopically expressing rpfF from a citrus strain of X. fastidiosa subsp. pauca exhibited less susceptibility to Xanthomonas citri subsp...
August 4, 2017: Molecular Plant-microbe Interactions: MPMI
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