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J Li, X J Guo, X L Ding, B M Lyu, J Xiao, Q L Sun, D S Li, W F Zhang, J C Zhou, C P Li, R C Yang
Objective: To assess the feasibility of HEAD-US scale in the clinical application of hemophilic arthropathy (HA) and propose an optimized ultrasound scoring system. Methods: From July 2015 to August 2017, 1 035 joints ultrasonographic examinations were performed in 91 patients. Melchiorre, HEAD-US (Hemophilic Early Arthropathy Detection with UltraSound) and HEAD-US-C (HEAD-US in China) scale scores were used respectively to analyze the results. The correlations between three ultrasound scales and Hemophilia Joint Health Scores (HJHS) were evaluated...
February 14, 2018: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
Y L Cao, W Li
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) which represented a new two-steps liver resection procedures has been considered a revolutionary innovation for liver surgery technique in recent 10 years, it was first discovered by Professor Lang in Germany in 2007.The first step of the classic surgical procedures for portal vein ligation and liver parenchyma, until the future liver remnant (FLR) increased to a sufficient remnant then resect the right three-leaf liver.With the development of ALPPS, the method of hepatic parenchyma separation and isolation materials have been modified, which improves the safety of operation...
April 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Alma Kairlapovna Ryskaliyeva, Murat Ergalievich Baltabayev, Aigul Moldakhmetovna Zhubatova
The thermodynamic properties of carbamide and its alkyl substituted were studied insufficiently. In this article, the enthalpies of combustion of ΔсН of some amides, anilides and amidic acids have been determined experimentally; their standard enthalpies of formation have been calculated. Linear dependences between the average atomic enthalpy of combustion of ΔcH amides and their basicity constants in acidic aqueous solutions of pKBH + have been established; a correlation that relates the enthalpies of combustion of amides and the corresponding amidic acids has been found...
March 2018: Acta Chimica Slovenica
Jéssica Rauane Teixeira Martins, Bruna Gabrielly Pereira Alexandre, Valéria Conceição de Oliveira, Selma Maria da Fonseca Viegas
OBJECTIVE: To understand, from the perspective of the professional, the Permanent Education (PE) in the vaccination room in its real context. METHOD: Multiple holistic-qualitative case studies, based on Maffesoli's Interpretive Sociology with 56 participants from four microregions of the Western Extended Region of Minas Gerais State. RESULTS: They present PE as infrequent and insufficient. They denote that the practical-theoretical experience with vaccine contributes to the work; the search for knowledge, starting from the professional itself; and the professional training fails to perform in the vaccination room...
2018: Revista Brasileira de Enfermagem
J L de Deus, A L A Dagostin, W A Varanda
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited by a calcium-induced calcium release mechanism. On the other hand, nitric oxide (NO) is reported to have an inhibitory role in testosterone production. Based on these observations, we investigated the interaction between the purinergic and nitrergic systems in Leydig cells of adult mice...
March 15, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Jianhua Tang, Yuqing Zhen, Ling Yu, Cui Lv, Juan Zheng, Hui Liang
OBJECTIVE: To investigate the neuropsychological characteristics and changes in CRP, S100B, MBP, HSP-7, and NSE in serum. METHOD: Sixty-six (66) patients treated in our hospital as CCCI group were chosen for our study, and 90 patients with depression were selected as the depression group. The patients in both groups were examined with CT perfusion, depression, anxiety and cognition evaluation. Their serum CRP, S100B, MBP, HSP-70 and NSE levels were detected. Neuropsychological and serum markers characteristics were compared...
January 2018: Revista da Associação Médica Brasileira
Claudia Cooper, Louise Marston, Julie Barber, Deborah Livingston, Penny Rapaport, Paul Higgs, Gill Livingston
BACKGROUND: There are widespread concerns about abuse of care home residents. We report, in the largest care home survey, prevalence of staff anonymously-reported, perpetrated/witnessed abusive behaviours towards care home residents over 3 months. We also report positive care behaviours. METHODS: 1544 staff in 92 English care home units completed the revised Modified Conflict Tactics Scale and Maslach Burnout Inventory. OUTCOMES: Most staff reported positive care behaviours, but specific person-centred activities were sometimes infrequent...
2018: PloS One
Fleur P Paling, Karina Olsen, Kristin Ohneberg, Martin Wolkewitz, Vance G Fowler, Mark J DiNubile, Hasan S Jafri, Frangiscos Sifakis, Marc J M Bonten, Stephan J Harbarth, Jan A J W Kluytmans
BACKGROUND: Identifying patients undergoing cardiothoracic surgery at high risk of Staphylococcus aureus surgical site infection (SSI) is a prerequisite for implementing effective preventive interventions. The objective of this study was to develop a risk prediction model for S. aureus SSI or bacteremia after cardiothoracic surgery based on pre-operative variables. MATERIALS/METHODS: Data from the Merck Phase IIb/III S. aureus vaccine (V710-P003) clinical trial were analyzed...
2018: PloS One
Staffan Morén, Per Åke Lindestad, Mats Holmström, Maria Mani
OBJECTIVES: The aim of the current study was to assess voice quality among adults treated for unilateral cleft lip and palate (UCLP), after one- or two-stage palate closure, and compare it to a noncleft control group. STUDY DESIGN: Cross-sectional study of patients with UCLP with long-term follow-up and noncleft controls. PARTICIPANTS: Patients with UCLP born between 1960 and 1987, treated at Uppsala University Hospital, Sweden, were examined (n = 73) at a mean of 35 years after primary surgery...
January 1, 2018: Cleft Palate-craniofacial Journal
Loïck Locatelli, Alain Golay
Psychotropic drugs can induce weight gain and a metabolic syndrome, reducing the quality of life and the life expectancy of patients. Weight gain is also responsible for poor adherence to treatment and therefore relapses of mental illness. This weight gain and the metabolic syndrome are insufficiently treated for obese patients with mental disorders. Recommendations exist.
March 21, 2018: Revue Médicale Suisse
Bastien Gregoire, Géraldine Pina-Jomir, Alexandre Bani-Sadr, Caroline Moreau-Triby, Marc Janier, Christian Scheiber
PURPOSE: The aim of this study was to determine the minimum acquisition time without decreasing lesion detectability of bone SPECT using a whole-body cadmium-zinc-telluride camera. METHODS: Patients referred for bone SPECT were retrospectively included. SPECT of 30 patients were reframed from native data (16 s/projection) to produce 10-, 5-, and 3-s/projection data sets. A "critical" acquisition time/projection was defined as that below which the SPECT quality becomes insufficient for interpretation, as determined by 3 reviewers using a 4-point scale (0 = quality insufficient for interpretation, 1 = average, 2 = good, 3 = excellent)...
March 20, 2018: Clinical Nuclear Medicine
Zhen-Zhen Li, Ya-Liang Huang, Hong-Jun Song, You-Juan Wang, Yan Huang
BACKGROUND: Solitary pulmonary nodules (SPNs) are common imaging findings. Many studies have indicated that F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG-PET/CT) is an accurate test for distinguishing benign and malignant SPNs. The aim of this study was to investigate the value of F-FDG-PET/CT in the diagnosis of malignant SPNs. METHODS: We systematically searched the PubMed and Embase databases up to March 2017, and published data on sensitivity, specificity, and other measures of diagnostic accuracy of F-FDG-PET/CT in the diagnosis of malignant SPNs were meta-analyzed...
March 2018: Medicine (Baltimore)
Jorge Valencia, Pablo Ryan, Alejandro Alvaro-Meca, Jesus Troya, Jorge Gutierrez, Guillermo Cuevas, Santiago Moreno
OBJECTIVES: Current harm reduction strategies will probably remain insufficient to eliminate HIV transmission among drug users. We aimed to estimate the HIV seroconversion rate among drug users followed at a Harm Reduction Unit (HRU) to evaluate the potential use of PrEP as a prevention tool. DESIGN AND METHODS: A cohort of drug users have been followed at a HRU in Madrid between 2013 and 2016. Individuals who were HIV-negative at baseline and who had at least one re-test for HIV infection were eligible...
March 20, 2018: AIDS
Emmanuel Marret, Raphael Cinotti, Laurence Berard, Vincent Piriou, Jacques Jobard, Benoit Barrucand, Dragos Radu, Samir Jaber, Francis Bonnet
BACKGROUND: Thoracic surgery for lung resection is associated with a high incidence of postoperative pulmonary complications. Controlled ventilation with a large tidal volume has been documented to be a risk factor for postoperative respiratory complications after major abdominal surgery, whereas the use of low tidal volumes and positive end-expiratory pressure (PEEP) has a protective effect. OBJECTIVE: To evaluate the effects of ventilation with low tidal volume and PEEP on major complications after thoracic surgery...
March 19, 2018: European Journal of Anaesthesiology
Marc Sorigue, Elisa Orna, Juan-Manuel Sancho
Lenalidomide has been associated with an increased risk of venous thromboembolism (VTE) in multiple myeloma. It is unclear whether patients with non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL) are also at such risk. We conducted a systematic review of the incidence of VTE in prospective trials of lenalidomide-treated patients with NHL or CLL. Sixty-eight unique reports were assessed for inclusion. For grade ≥3 VTE, 98 events were reported in 3043 patients (60 studies) (crude incidence: 3...
March 21, 2018: Leukemia & Lymphoma
Rebecca Simon, Sharon W Lahiri
OBJECTIVE: To identify provider recommendations and barriers in obesity management in a multicenter academic health system with extensive weight-loss management resources. METHODS: A 26-question online survey was sent to attending physicians, trainees, and advanced practice providers in primary care specialties (internal medicine, family medicine, women's health) and endocrinology. RESULTS: The survey response rate was 26% (111/430). Of respondents, 50% were internal medicine, 24% family medicine, 16% women's health, and 9% endocrinology...
March 21, 2018: Endocrine Practice
Yuan Yue, Lone Hymøller, Søren Krogh Jensen, Charlotte Lauridsen
The objective of this study was to investigate the possible beneficial effect of vitamin D repletion on certain immune parameters of vitamin D insufficient dairy cows. Twenty dairy cows in late lactation were treated daily with vitamin D in five different ways: sunlight exposure (SUN), D2 supplementation combined with sunlight exposure (D2SUN), D2 supplementation (D2), D3 supplementation (D3), and D2 and D3 supplementation combined (D2D3). The cows had very low vitamin D levels at d 0 because of the vitamin D deprivation before the study...
March 21, 2018: Archives of Animal Nutrition
Lamia El Badawi
In a 2012 opinion, the common consultative committee of ethics of the INRA and the CIRAD commented on the known and potential applications of nanotechnologies in agriculture and food domains. He recommends the adoption of sufficient measures of evaluation and risk assessment and management for the time being still insufficient. He also recommends for the researchers to be the main interlocutor not only of the sanitary and environmental public authorities but also of the citizens who do not perceive the practical interest of these technologies...
October 13, 2017: Journal International de Bioéthique et D'éthique des Sciences
Yu S Vinnik, R A Pakhomova, L V Kochetova, E A Voronova, V V Kozlov, A K Kirichenko
AIM: To develop predictive model for hepatic insufficiency in obstructive jaundice. MATERIAL AND METHODS: Obstructive jaundice was modeled by the author's method on 48 mini pigs, while morpho-functional features of erythrocytes were studied by using of INTEGRA Aura atomic force microscope (NT-MDT, Zelenograd, Russia). Histological specimens were stained with hematoxylin and eosin. Discriminant analysis was used to create predictive model for hepatic insufficiency...
2018: Khirurgiia
M Somers, C Peleman, K Van Malderen, W Verlinden, S Francque, H De Schepper
BACKGROUND: The treatment of fecal incontinence (FI) depends upon the dominant pathophysiology: impaired sphincter contractility or overflow due to pelvic floor dyssynergia and insufficient rectal emptying. In this study, we aimed to define the manometric and anorectal ultrasound characteristics in FI patients with and without constipation. METHODS: We did a retrospective study of 365 anal manometries, performed between October 2012 and July 2015, in patients with FI...
October 2017: Acta Gastro-enterologica Belgica
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