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Cord M Brundage, Rebecca A Packer, Matthew D Jones
OBJECTIVE: To describe the magnetic resonance (MR) image appearance of 5 hemostatic agents placed in the brain, and to review their clinical application. STUDY DESIGN: Descriptive ex vivo and in vivo study. ANIMALS: Canine cadavers (n=4), client-owned dogs (n=4). METHODS: Heads from 4 canine cadavers were used, each with 5 hemostatic agents placed in specific locations in the brain. Hemostatic agents were used in their native form in 2 cadaveric brains, and in 2 others the materials were saturated with fresh whole blood prior to placement to mimic application in a field of active hemorrhage...
September 23, 2016: Veterinary Surgery: VS
Sung Hyun Kim, Hye Sung Yoon, Chang Hoon In, Kyung Sik Kim
BACKGROUNDS/AIMS: This study evaluated the hemostatic effects of a novel oxidized regenerated cellulose, SurgiGuard®, during liver surgery, using a reproducible and clinically relevant animal model. METHODS: Fifteen mini-pigs underwent left partial hepatectomy. They were randomized to treatment of the resected surface with SurgiGuard® (Group C [test], n=5), Surgicel® (Group B [reference], n=5), or nothing (Group A [control], n=5). Blood loss was measured 5, 7 and 9 min after resection...
August 2016: Korean Journal of Hepato-biliary-pancreatic Surgery
Cole B Hirschfeld, Theodore H Schwartz, Bhupesh Parashar, A Gabriella Wernicke
PURPOSE: Seed migration after interstitial prostate brachytherapy has been well documented in the literature. However, there have been no detailed reports of seed migration after permanent interstitial brachytherapy to treat cerebral malignancies. In this article, the authors report a rare case of seed migration after adjuvant cesium-131 ((131)Cs) brachytherapy was used to treat a large paraventricular brain metastasis. METHODS AND MATERIALS: The patient was a 63-year-old man with a 5...
September 2016: Brachytherapy
Yasmin Abu-Ghanem, Zohar Dotan, Issac Kaver, Dorit E Zilberman, Jacob Ramon
Hemostatic agents(HAs) have gained increasing popularity as interventions to improve perioperative haemostasis and diminish the need for allogeneic red cell transfusion(PBT) despite a paucity of data supporting the practice. The aim of the current study is to examine the efficacy of HAs in reducing the rate of hemorrhagic complications during partial nephrectomy(PN). Data on 657 patients, who underwent elective PN between 2004-2013, were analyzed. The impact of HAs and SURGICEL was evaluated by comparing four sequential groups of patients: Group1 = Sutures alone, Group2 = sutures and HA, Group3 = sutures and SURGICEL, Group4 = both HA and SURGICEL...
2016: Scientific Reports
Huseyin Karasu, Işil Güzel
OBJECTIVES: We designed this study to evaluate the effect of TachoComb and to compare it with SurgiWrap, Surgicel, and Lyodura in an experimental rat model for epidural fibrosis (EF). METHODS: This prospective and experimental rat model study was performed at Dicle University, School of Medicine, Department of Neurosurgery, in Diyarbakir, Turkey, between January 2005 and June 2005, using 50 Sprague Dawley rats (30 female and 20 male) with a mean weight of 290 g...
March 30, 2016: Ideggyógyászati Szemle
Luigi Cormio, Gennaro Cormio, Giuseppe Di Fino, Carmen Scavone, Francesca Sanguedolce, Vera Loizzi, Giuseppe Carrieri
Surgicel(®) is an absorbable sterile mesh composed of oxidized cellulose that is used to control intraoperative capillary or venous bleeding, due to its capacity to bind hemoglobin, thus allowing the formation of an artificial clot. In the present study, a large granuloma mimicking ovarian cancer, which developed following placement of a Surgicel(®) sponge during a combined pubovaginal sling procedure and cystocele repair, is reported. The aim of the present case report is to emphasize the fact that hemostatic measures should be removed following their use, and to alert surgeons to the risk of using and leaving in situ oxidized cellulose...
August 2016: Oncology Letters
Ali Alper Bayram, Ahmet Erdem Kilavuz, Gediz Murat Serin
Structural deficiencies of the nasal dorsum are most commonly of congenital, traumatic, or iatrogenic etiology. Various grafts, including autografts, homografts, and synthetic materials, have been used to this end and are described in the literature.Autologous septal cartilage is the most commonly used graft material when limited augmentation rhinoplasty is planned. However, it is difficult to retain sufficient cartilage to allow of such augmentation in instances where most of the septal cartilage has been used...
October 2016: Journal of Craniofacial Surgery
Jinghao Chen, Guangqian Lan, Keying Li, Shibei Liu, Kun Yu, Jiawei Liu, Hua Tang, Fangying Dai, Dayang Wu
In this study, we attempted to modify cotton gauze by partial carboxymethylation by varying the reaction time and concentration of monochloroacetic acid and sodium hydroxide. For each experiment, the relative value of the degree of substitution (DS) of the modified cotton gauze was evaluated and the whole blood clotting time (WBCT) and water absorption property were compared with cotton gauze and Surgicel. This revealed that, following an initial decrease, WBCT gradually increased. Using rabbit ear artery and liver haemorrhage models, the performance of the optimal modified gauze was compared to that of Surgicel and unmodified cotton gauze...
September 2016: Journal of the Mechanical Behavior of Biomedical Materials
Jingyun Liu, Wandong Hong, Wenzhi Wu, Haizhen Ni, Mengtao Zhou
Delayed absorption of oxidized cellulose (Surgicel; Johnson & Johnson, New Brunswick, NJ) may mimic a pseudoabscess or a recurrent mass on sonography after tumor surgery. Here we present 3 cases of thyroidectomy in which Surgicel was still apparent on sonography after 26 to 47 months of follow-up. We show sonographic findings and discuss the utility of sonography for diagnosis of delayed absorption of Surgicel in post-thyroidectomy patients.
June 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Francisco Sepulveda, Alfredo Aliaga, Daniela Fleck, Mario Fernandez, Alejandro Mercado, Roberto Vilches, Francisco Moya, Rodrigo Ledezma, Diego Reyes, Fernando Marchant
INTRODUCTION: The role of hemostatic agents as an adjunct for closure of the nephrostomy tract in tubeless percutaneous surgery (tubeless percutaneous nephrolithotomy [tPNL]) has been previously evaluated, observing a potential benefit in terms of reduced bleeding and urinary leakage. We assessed the rate of postoperative complications after the use of hemostatic agents for sealing the nephrostomy tract in patients undergoing tPNL at our institution. SUBJECTS AND METHODS: We performed a retrospective analysis of 52 consecutive patients undergoing tPNL at our center between January 2010 and December 2013...
April 2016: Urology Annals
Jeffrey W Chadwick, Karel terBrugge, David K Lam
PURPOSE: This report describes a case of a 32-year-old woman who had been diagnosed with a facial arteriovenous malformation during childhood. Because this patient possessed a major risk of perioperative hemorrhage, the use of several local hemostatic measures was thoroughly explored before routine exodontia. MATERIALS AND METHODS: Selective embolization of the right superior thyroid artery was performed intraoperatively and a novel hemostatic technique using a combination of a packing of Gelfoam wrapped in Surgicel was placed within the extraction sites and sealed with SwiftSet...
August 2016: Journal of Oral and Maxillofacial Surgery
G Ziade, A L Hamdan, M T Homsi, I Kazan, U Hadi
BACKGROUND: Spontaneous onset transethmoidal meningocele is a rare entity among the adult population. METHODS: A retrospective chart review was performed and cases of adults diagnosed with spontaneous transethmoidal meningoceles from November 2000 till February 2014 were reported. Data collected included demographics, clinical presentation, diagnostic modalities, and results. Intraoperative findings, the type of surgical reconstruction performed, and the percentage of recurrence, if present, were also reported...
2016: TheScientificWorldJournal
Wei Zhang, Yan Wang, Xianxian Sui, Yulin Sun, Daohai Chen
PURPOSE: To detect whether chitin and sepia ink sponge (CS) can promote wound healing and elevate impact of CS on phagocytosis ability of macrophages. METHODS: Forty-eight rats were assigned to four groups: Normal group (Normal), negative control group (Con), chitin and sepia ink sponge group (CS) and positive control Surgicel Gauze(r) group (SG). Deep second-degree burn model was created in rats. Wound area was recorded by digital imaging and determined using Image J software...
February 2016: Acta Cirúrgica Brasileira
Idiris Altun
OBJECTIVE: To evaluate and compare the histopathologic effects of various hemostatic agents used in spinal surgery on an experimental laminectomy model in rats. METHODS: There were 110 rats randomly allocated into 11 groups, including sham, control, AnkaferdBlood Stopper (herbal hemostatic), SeraSeal (agar and bovine factor proteins), FLOSEAL (gelatin granules and thrombin), SURGIFLO (gelatin paste), HELITENE (absorbable collagen), Beriplast (fibrin sealant containing fibrinogen, factor XIII, and thrombin), TISSEEL (fibrin sealant), BLOODCARE (hemostatic powder), and SURGICEL (oxidized cellulose polymer) groups...
June 2016: World Neurosurgery
O Onur Erol
BACKGROUND: All grafts present the potential problem of late visibility, distortion, and (occasionally) absorption. To overcome these problems and obtain a smoother surface, in 1989, the author initiated the use of finely diced cartilage wrapped in Surgicel. It is well known that the resolution of edema at the end of 1 year postoperatively is approximately 90 to 95 percent. Complete resolution continues until the end of 4 years postoperatively. However, it is important to understand what occurs beyond 4 years, and how the nose changes as the face ages...
February 2016: Plastic and Reconstructive Surgery
John S Fisher, Ricardo Gonzalez, Philippe E Spiess
We present a case of an 87-year-old female who was evaluated for an 8.5 cm left sided renal mass concerning for malignancy. The patient was transiently thrombocytopenic over the previous 4 months with platelet counts ranging from 50,000 to 125,000 plt/mcL and experienced diffuse hemorrhage during radical nephrectomy with failure to achieve mechanical hemostasis or fulguration. Following Surgicel (Ethicon; Somerville, New Jersey) application, we applied Tisseel (Baxter; Deerfield, IL) to the nephrectomy bed with complete hemostasis of bleeding foci...
January 2016: Urology Case Reports
Yuri Genyk, Tomoaki Kato, James J Pomposelli, J Kelly Wright, Linda S Sher, Vilhelm Tetens, William C Chapman
BACKGROUND: Local hemostatic agents are important for the control of bleeding during liver resection when standard surgical techniques are insufficient. STUDY DESIGN: This was a multicenter, randomized, open-label study to compare fibrin sealant patch (FSP; TachoSil; Takeda Pharma A/S) with oxidized regenerated cellulose gauze (ORCG; Surgicel Original; Ethicon) for the secondary treatment of local bleeding after hepatic resection in adult and pediatric patients...
March 2016: Journal of the American College of Surgeons
Feng Zhang, Michael J Bonidie, Stephen M Ventrelli, Alessandro Furlan
Oxidized regenerated cellulose (Ethicon Surgicel) is often used during surgery to achieve hemostasis. The appearance of Surgicel on postoperative computed tomography (CT) may be mistaken for abscess. Meanwhile, the literature regarding its ultrasound appearance remains scant. We report the CT and sonographic appearances of Surgicel in the right ovary of a 21-year-old woman presenting to the emergency department with pelvic pain 7 days after ovarian cystectomy. The patient was discharged home with only supportive measures, and follow-up ultrasound obtained 26 days later demonstrated resolution of the sonographic abnormality...
December 2015: Radiology case reports
Derek Martyn, Lisa M Meckley, Gavin Miyasato, Sangtaeck Lim, Jerome B Riebman, Richard Kocharian, Jillian G Scaife, Yajing Rao, Mitra Corral
BACKGROUND: Adjunctive hemostats are used to assist with the control of intraoperative bleeding. The most common types are flowables, gelatins, thrombins, and oxidized regenerated celluloses (ORCs). In the US, Surgicel(®) products are the only US Food and Drug Administration-approved ORCs. OBJECTIVE: To compare the outcomes of health care resource utilization (HRU) and costs associated with using ORCs compared to other adjunctive hemostats (OAHs are defined as flowables, gelatins, and topical thrombins) for surgical procedures in the US inpatient setting...
2015: ClinicoEconomics and Outcomes Research: CEOR
Kreg Howk, Jason Fortier, Robert Poston
BACKGROUND: Achieving hemostasis during surgery is a common challenge across surgical specialties and procedures, including cardiovascular and peripheral vascular procedures. Although several hemostatic agents are available, they all become less effective as bleeding becomes more vigorous. Veriset™ hemostatic patch is a topical hemostatic agent that has been approved for use on solid organs and in soft tissue. The primary aim of these studies was to assess the safety of Veriset hemostatic patch during cardiovascular and peripheral vascular procedures...
February 2016: Annals of Vascular Surgery
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