keyword
https://read.qxmd.com/read/37789790/a-single-centre-report-of-acute-pyelonephritis-in-a-patient-after-kidney-transplantation-analyses-of-risk-factors
#21
JOURNAL ARTICLE
Igor Gala, Tatiana Baltesova, Stefan Hulik, Rastislav Kalanin, David Adandedjan, Jana Katuchova, Luboslav Bena
BACKGROUND: Urinary tract infections (UTI) are the most common infectious complications after kidney transplantation (KTx) with highest incidence in the first three months of transplantation. UTI in transplant recipients increase morbidity and mortality, risk of graft failure and incidence of acute rejection episodes. According to published data, urinary tract infections significantly affect graft survival. The aim of our study was to identify possible risk factors for the development of UTI...
2023: Bratislavské Lekárske Listy
https://read.qxmd.com/read/37742321/association-between-mycophenolate-mofetil-use-and-subsequent-infections-among-hospitalized-patients-with-systemic-lupus-erythematosus-a-nested-case-control-study
#22
JOURNAL ARTICLE
Qingqing Guo, Xueyi Zhang, Siqin Sun, Xiaojun Tang, Wei Shen, Jun Liang, Genhong Yao, Linyu Geng, Shuai Ding, Hongwei Chen, Hong Wang, Bingzhu Hua, Huayong Zhang, Dandan Wang, Xuebing Feng, Lingyun Sun, Ziyi Jin
INTRODUCTION: The association between mycophenolate mofetil (MMF) and infection in patients with systemic lupus erythematosus (SLE) has not been clarified. This study evaluated the degree and factors in effect of MMF use on infection in patients with SLE. METHODS: A hospitalized-based observational study was conducted to collect medical records on patients with SLE during 2010-2021. A nested case-control study was performed among 3339 patients with SLE, including 1577 cases and 1762 controls by whether they developed any type of infection...
December 2023: Rheumatology and Therapy
https://read.qxmd.com/read/37737333/a-case-of-emphysematous-pyelonephritis-in-an-older-man-with-poorly-controlled-type-2-diabetes-mellitus
#23
JOURNAL ARTICLE
Mayuka Nishikawara, Makoto Harada, Daiki Yamazaki, Tetsuji Kakegawa, Koji Hashimoto, Yuji Kamijo
Emphysematous pyelonephritis (EPN) is a necrotizing bacterial infection characterized by gas retention and a poor prognosis. We present the case of a 75-year-old man who was diagnosed early with EPN and received multidisciplinary treatment. He had poorly controlled type 2 diabetes mellitus (DM) and chronic kidney disease (CKD), and was treated with oral hypoglycemic drugs, including a sodium-glucose co-transporter-2 inhibitor. He experienced the onset of back pain in the midsection of his back, tenderness in the costovertebral angle, and a high fever (> 39 °C), accompanied by tachycardia, hypotension, and tachypnea...
September 22, 2023: CEN Case Reports
https://read.qxmd.com/read/37705388/outcomes-of-asymptomatic-histologic-pyelonephritis-of-kidney-transplant
#24
JOURNAL ARTICLE
Pooja Budhiraja, Richard Butterfield, Juan Gea-Banacloche, Sundararaman Swaminathan, Maxwell L Smith, Hassan A Khamash, Hay Me Me, Lavanya Kodali, Girish K Mour, Sumi Nair, Suman Misra, Raymond L Heilman
BACKGROUND: Urinary Tract Infections are the most common post-transplant infection and can have varied presentations. This study aimed to describe the outcomes of kidney transplant recipients with asymptomatic histologic pyelonephritis on allograft biopsy. Histologic Pyelonephritis was defined as neutrophil cast or neutrophilic tubulitis, interstitial infiltrates with predominant neutrophils, and no evidence of rejection or glomerulonephritis on biopsy. METHODS: The study included 123 kidney transplant recipients, of whom 95 underwent protocol biopsies, and 28 had biopsies for elevated creatinine within the first 2 years of a kidney transplant...
September 13, 2023: Clinical Transplantation
https://read.qxmd.com/read/37676477/concurrent-emphysematous-cystitis-and-emphysematous-pyelonephritis-in-a-patient-with-extrarenal-pelvis
#25
JOURNAL ARTICLE
Elham Barahimi, Ayoub Basham, Ebrahim Evazi, Mehdi Hassaniazad, Behnoush Heidari, Mostafa Mazaheri
We report co-occurrence of emphysematous cystitis and emphysematous pyelonephritis (EC/EPN) in a 64-year-old female with poor-controlled diabetes mellitus (DM) that presented with flank pain, fever, and hematuria that turned out to have a bilateral extrarenal pelvis. On examination, she was feverish, and the costovertebral angle was tender. By considering herhemoglobin A1C, her DM was out of control. Inflammatory markers elevated. Renal function tests were impaired. Urine culture was positive for extended-spectrum beta-lactamase Escherichia coli...
September 7, 2023: CEN Case Reports
https://read.qxmd.com/read/37675415/urinary-tract-infection-in-diabetics-hospitalized-in-befelatanana-hospital-antananarivo-epidemiological-clinical-biological-profiles-and-risk-factors-for-multidrug-resistant-bacterial-infection
#26
Rija Eric Raherison, Sitraka Angelo Raharinavalona, Thierry Razanamparany, Theo Njakasoa Randrianotahiana, Tsikinirina Valisoa Randrianomanana, Miora Maeva Arielle Andrianiaina, Andrianirina Dave Patrick Rakotomalala, Radonirina Lazasoa Andrianasolo
KEY CLINICAL MESSAGE: The main type of urinary tract infection in hospitalized diabetics in Antananarivo is acute pyelonephritis; Escherichia coli is the most isolated uropathogen; imipenem, amikacin, fosfomycin and ceftriaxone are the major antibiotics for which Escherichia coli retain good sensitivity; Type 2 diabetes is predictive factor for infection by multidrug resistant bacteria. ABSTRACT: This study aimed to describe the epidemiological-clinical profiles of diabetics hospitalized for bacterial urinary tract infections in the Endocrinology Department of Befelatanana Hospital, to identify the main bacteria responsible, their antibiotic sensitivity profile and the factors associated with multidrug-resistant bacterial infection...
September 2023: Clinical Case Reports
https://read.qxmd.com/read/37667766/endogenous-endophthalmitis-secondary-to-perirenal-abscess
#27
Nemecio Lizana, Diego Parrao, Matías Larrañaga, Juan P Figueroa-Vercellino, Karen Pozo, Juan Cristóbal Bravo
INTRODUCTION: Endogenous Endophthalmitis is a rare ocular infection but with poor visual prognosis for most patients. Its most frequent etiology is Klebsiella spp., associated with hepatic abscesses and less frequently with perirenal abscesses. CASE PRESENTATION: We present a 61-year-old woman with a history of poorly controlled diabetes mellitus 2 that consulted several times for acute pyelonephritis with torpid evolution, associated with endogenous endophthalmitis in her right eye that required evisceration...
September 2023: IJU case reports
https://read.qxmd.com/read/37667725/xanthogranulomatous-pyelonephritis-with-extension-to-the-liver-a-case-report
#28
Saad Bkiri, Fayçal Abbad, Mohammed Ghadouane
Xanthogranulomatous pyelonephritis (XGP) is an uncommon condition representing 1% of all renal infections. XGP due to complicated pyelonephritis associated with hepatic abscess is an extremely rare complication and has rarely been reported in the literature. We report a rare case of a 54-year-old female with a history of diabetes and recurrent urinary tract infections (UTI) who presented with acute right flank pain and fever which had been ongoing for four days. CT scan showed multiple bilateral obstructive nephrolithiasis associated with a liver abscess...
August 2023: Curēus
https://read.qxmd.com/read/37605691/successful-treatment-of-bilateral-renal-mucormycosis-with-isavuconazole-a-case-report
#29
Yaseen Najjar, Shirley Botros, Emily Acker, Ananthakrishnan Ramani, Kelly Beers
Isolated renal mucormycosis (IRM) is a rare disease with high mortality, more commonly seen in immunocompromised patients. Management has traditionally included antifungal drugs with or without nephrectomy. We present the case of a 34-year-old female with a past medical history of type 1 diabetes mellitus and intravenous heroin use who presented with fever, flank pain, hematuria, and vomiting. She was found to have an oliguric acute kidney injury (AKI) with a serum creatinine (Cr) of 2.5 mg/dL. CT showed bilateral emphysematous pyelonephritis and ureteral cultures grew Rhizopus species...
July 2023: Curēus
https://read.qxmd.com/read/37575407/a-patient-with-generalized-weakness-a-case-report
#30
JOURNAL ARTICLE
Darby Graham, Manparbodh Kaur, John Costumbrado, Sassan Ghassemzadeh
UNLABELLED: Emphysematous pyelonephritis (EPN) is a rare and life-threatening sequalae of a urinary tract infection marked by a gas-producing necrotizing infection of the renal parenchyma requiring prompt treatment. It has been found to be correlated with uncontrolled diabetes mellitus and is more common in females due to their increased susceptibility to urinary tract infections. Early recognition and treatment of EPN are essential to improve the patient's prognosis and prevent further complications...
July 2023: Journal of education & teaching in emergency medicine
https://read.qxmd.com/read/37556105/comparison-of-prognosis-of-five-scoring-systems-in-emphysematous-pyelonephritis-patients-requiring-intensive-care
#31
JOURNAL ARTICLE
Mokhtar Bibi, Kays Chaker, Yassine Ouanes, Ramla Baccouch, Mohamed Anouar Madani, Houssem Mediouni, Boutheina Mosbahi, Kheireddine Mourad Dali, Moez Rahoui, Yassine Nouira
INTRODUCTION: Our study aimed to evaluate the performance of Quick Sepsis-related Organ Failure Assessment (qSOFA), Modified Early Warning Score (MEWS), National Early Warning Score (NEWS), Systemic Inflammatory Response Syndrome (SIRS), and Global Research in the Emphysematous Pyelonephritis group (GREMP) in predicting the need of admission in intensive care units (ICU) for emphysematous pyelonephritis (EPN) patient. PATIENTS AND METHODS: In this retrospective study, we reviewed 70 patients admitted to our department from January 2008 to October 2022...
August 9, 2023: International Urology and Nephrology
https://read.qxmd.com/read/37539405/escherichia-coli-meningitis-in-a-patient-with-urinary-tract-infection-a-case-report
#32
Aglisa Memia, Xheni Deda, Andrea Broka, Mariana Kawalet, Judith Berger
This article discusses a case of Escherichia coli (E. coli) meningitis resulting in altered mental status in a patient with multiple pre-existing comorbidities. The case highlights the underestimated risk of community-acquired gram-negative meningitis in adults, which can have a high mortality rate, particularly in elderly patients with sepsis and urinary tract infections. Diagnosis of E. coli meningitis was confirmed by analyzing cerebrospinal fluid obtained through the lumbar puncture and blood cultures. Treatment involved prompt administration of antibiotics and supportive care...
July 2023: Curēus
https://read.qxmd.com/read/37520756/emphysematous-kidney-related-to-the-use-of-empagliflozin-in-a-diabetic-woman
#33
Pablo Echeverria, Julia Saa, Luis D Paz Y Miño
BACKGROUND/OBJECTIVE: Sodium-glucose cotransporter-2 (SGLT2) inhibitors are part of the treatment for hyperglycemia in patients with diabetes. These drugs have shown important benefits including cardiovascular and renal protection among people with diabetes. CASE REPORT: We report a case of a 60-year-old woman with diabetes who presented to the emergency department complaining of left flank pain radiating to the groin. The patient was on multiple antidiabetic medications, including a recently added empagliflozin, considering the difficulty in controlling hyperglycemia...
2023: AACE Clinical Case Reports
https://read.qxmd.com/read/37505282/sglt2i-and-glp-1-ra-therapy-in-type-1-diabetes-and-reno-vascular-outcomes-a-real-world-study
#34
JOURNAL ARTICLE
Matthew Anson, Sizheng S Zhao, Philip Austin, Gema H Ibarburu, Rayaz A Malik, Uazman Alam
AIMS/HYPOTHESIS: Insulin is the primary treatment for type 1 diabetes. However, alternative glucose-lowering therapies are used adjunctively, but importantly are off-label in type 1 diabetes. Little work has previously been undertaken to evaluate safety with long-term efficacy and cardio-renal benefits of such therapies. We sought to investigate the real-world impact of sodium-glucose cotransporter 2 inhibitor (SGLT2i) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy in individuals with type 1 diabetes in relation to effect on blood glucose levels, adverse events and cardio-renal outcomes...
October 2023: Diabetologia
https://read.qxmd.com/read/37451619/severe-disseminated-infection-by-hypermucoviscous-klebsiella-pneumoniae-successfully-treated-by-intensive-therapy-with-continuous-hemodiafiltration-using-an69st-a-case-report-and-review-of-the-literature
#35
Kazuhiro Tada, Ryoko Shibata, Tsubasa Nakamura, Yoshihiro Kawaguchi, Yuki Nakano, Hidehiro Ishii, Kazuya Ura, Hiroyoshi Yamada, Shinichi Maekawa, Kenji Ito, Kosuke Masutani
Klebsiella pneumoniae (Kpn) is one of the most common gram-negative bacilli causing lung, urinary tract, and biliary tract infections. However, as a distinct entity from classic Kpn, hypervirulent Kpn causing liver abscess, endophthalmitis, and lung abscess with poor prognoses has been reported mainly in East and Southeast Asia since the mid-1980s. Although the definition of hypervirulent Kpn is unclear, the hypermucoviscosity of Kpn is considered an important feature of hypervirulence. We present a case of emphysematous pyelonephritis accompanied by septic shock and acute kidney injury caused by hypermucoviscous Kpn infection that was successfully treated by intensive treatment...
July 12, 2023: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/37427162/emphysematous-pyelonephritis-complicated-by-septic-shock-treated-with-antibiotic-therapy-alone-a-case-report
#36
JOURNAL ARTICLE
Manal Merbouh, Ghizlane El Aidouni, Houssam Bkiyar, Brahim Housni
UNLABELLED: Emphysematous pyelonephritis (EPN) is a rare and serious complication of urinary tract infections that mainly occurs in diabetic patients. It results in the development of aerobic gas-forming bacteria1. Diagnosis is based mainly on a computed tomography scanner. Therapeutic management is based on the patient's clinical condition and radiological classification. CASE PRESENTATION: We present a case of a 64-year-old female patient with type 2 diabetes under insulin and hypertension under amlodipine, who was admitted to the intensive care unit for a state of septic shock on EPN...
July 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/37401705/-features-of-nephrotransplant-blood-flow-during-kidney-transplant
#37
JOURNAL ARTICLE
S S Dunaevskaya, A A Kosik, M F Kuchkarov, E V Repina, I S Popov
INTRODUCTION: Kidney transplantation, which provides a high quality of life for patients with terminal chronic renal failure worldwide, is recognized as one of the main achievements of modern medicine. Graft dysfunction is an urgent problem, the one-year survival rate of renal transplants is from 93% (from cadaveric donors) to 97% (from living donors), the five-year survival rate is on average 95%. The aim of the study consisted in determining the features of renal graft blood flow in the early post-transplantation period...
May 2023: Urologii︠a︡
https://read.qxmd.com/read/37389405/emphysematous-pyelonephritis-after-urinary-diversion-by-percutaneous-nephrostomy-in-patient-with-advanced-cervical-cancer-a-case-report
#38
Jeferson Rodrigo Zanon, Henrique Durante, Leandro de Medeiros Nóbrega, Guilherme Accorsi, Priscila Grecca Pedrão, Ricardo Dos Reis
Emphysematous pyelonephritis is a severe kidney infection that is common in women and patients with diabetes mellitus, but rare in cancer patients. A 64-year-old patient with advanced uterine cervical cancer developed emphysematous pyelonephritis after urine diversion by percutaneous nephrostomy of the left kidney, which is a possible approach to this infection. Antibiotic therapy was started to achieve clinical improvement and preserve renal function, and radical nephrectomy was not an option due to the functional exclusion of the contralateral kidney...
2023: SAGE Open Medical Case Reports
https://read.qxmd.com/read/37342743/deceased-donor-kidney-transplantation-outcomes-at-a-sri-lankan-center-a-comprehensive-single-center-analysis
#39
JOURNAL ARTICLE
Mohamed Mujahith Salahudeen Buhary Ahamed, Mohamed Nazar Abdul Latiff
Background Chronic kidney disease (CKD) causes significant morbidity and mortality in patients and incurs a huge burden on healthcare expenses globally. Renal replacement therapy becomes imperative when patients reach end-stage renal disease. Kidney transplant is the best modality of choice for the majority of patients, and deceased donor kidney transplantation is the major contributor in the majority of countries. We present an outcome study in Sri Lanka for deceased donor kidney transplantation. Methodology This is an observational study conducted at the Nephrology Unit 1 at the National Hospital of Sri Lanka, Colombo, in patients who had undergone deceased donor kidney transplantation from July 2018 to mid-2020...
May 2023: Curēus
https://read.qxmd.com/read/37304982/a-rare-case-of-air-cysto-uretero-pyelogram-due-to-emphysematous-cystitis
#40
Shakti Swarup Sarangi, Deepak Prakash Bhirud, Shiv Charan Navriya, Arjun Singh Sandhu
Emphysematous infection of the urinary tract is a hazardous condition and is life-threatening if not managed quickly. We report an 82-year-old woman with uncontrolled diabetes mellitus and urethral stricture who presented with emphysematous cystitis with the gas reaching up to the pelvicalyceal system on the left side (emphysematous pyelonephritis) and appearing in X-ray as air pyelogram. The patient was managed with drainage and intravenous antibiotics and she recovered.
2023: Indian Journal of Urology: IJU: Journal of the Urological Society of India
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