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https://www.readbyqxmd.com/read/27891373/retrospective-comparison-of-clinical-characteristics-and-in-hospital-outcomes-among-diabetic-and-non-diabetic-adults-with-acute-pyelonephritis
#1
Shailesh C Trivedi, Sanjeev R Phatak, Renu S Trivedi
INTRODUCTION: Acute Pyelonephritis (APN) is a common infection in community. Diabetes Mellitus (DM) may have different effect on clinical characteristics and outcomes of APN compared to non-diabetic individuals. AIM: To compare clinical characteristics and assess outcomes of APN patients with and without DM. MATERIALS AND METHODS: A retrospective analysis of 122 patients with DM (n=61) and without DM (n=61) was conducted at a single, private, urban set-up from Gujarat, India...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27876693/a-case-of-septic-shock-due-to-serratia-marcescens-pyelonephritis-and-bacteremia-in-a-patient-receiving-empagliflozin
#2
Wesley D Kufel, Ali Scrimenti, Jeffrey M Steele
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been associated with serious urinary tract infections (UTIs) including pyelonephritis and urosepsis. The Food and Drug Administration (FDA) issued a label change to include this warning in December 2015 due to a small number of cases (n = 19) reported to the FDA Adverse Event Reporting System. Details of these cases are limited and none involved empagliflozin. To date, there has been no published literature comprehensively describing serious UTIs attributed to empagliflozin...
November 21, 2016: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27821396/morphine-induced-hearing-loss
#3
Leire Leache, Irene Aquerreta, Libe Moraza, Ana Ortega
PURPOSE: A case of severe bilateral sensorineural hearing loss associated with oral morphine is reported. SUMMARY: A 52-year-old Spanish man was admitted to the intensive care unit with a Glasgow Coma Scale score of 3, a fever, and sudden hearing loss with tinnitus in both ears. His medical history included type 2 diabetes mellitus, depression, sleep disorder, and hypertension. The patient also had pyelonephritis in 2011 and pulmonary embolism in 2014, requiring the placement of an inferior vena cava filter and chronic anticoagulation...
November 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27798778/hospitalizations-for-chronic-conditions-among-indigenous-australians-after-medication-copayment-reductions-the-closing-the-gap-copayment-incentive
#4
Amal N Trivedi, Ross Bailie, Jodie Bailie, Alex Brown, Margaret Kelaher
BACKGROUND: To close health disparities between Indigenous and non-Indigenous Australians, the Australian government in 2010 reduced medication copayments for Indigenous Australians living with, or at risk of, a chronic disease. Patients were registered for this incentive by their general practitioner. OBJECTIVE: To assess rates of hospitalizations for chronic conditions among Indigenous Australians before and after copayment reductions. DESIGN: Observational time-trend study of hospitalizations for chronic conditions sensitive to medication adherence...
October 31, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27747456/biphasic-decline-in-renal-function-after-radical-cystectomy-with-urinary-diversion
#5
Katsuhiro Makino, Tohru Nakagawa, Atsushi Kanatani, Taketo Kawai, Satoru Taguchi, Masafumi Otsuka, Akihiko Matsumoto, Hideyo Miyazaki, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yukio Homma
BACKGROUND: We evaluated short- and long-term renal function in patients after radical cystectomy with urinary diversion and identified risk factors for the deterioration of renal function. METHODS: This retrospective study comprised 91 patients who underwent radical cystectomy and urinary diversion for bladder cancer and survived ≥3 years after surgery. The estimated glomerular filtration rate (eGFR) was calculated, and longitudinal changes of eGFR were assessed...
October 17, 2016: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27688864/development-of-epidural-and-paraspinal-abscesses-after-insufficient-evaluation-and-treatment-of-acute-pyelonephritis-caused-by-staphylococcus-aureus
#6
Mi Jeoung Kim, Hyang Mo Koo, Woo Joo Lee, Jin Hwan Choi, Mi Nyong Choi, Sang Young Park, Woo Jung Kim, Seung Yeon Son
Diagnoses of pyelonephritis caused by Staphylococcus aureus should be accompanied by investigations of concomitant bladder obstruction and metastatic infections, especially to the spine or heart. Complicated pyelonephritis due to S. aureus requires more than 2 weeks of antibiotics, which is the typically recommended treatment duration for pyelonephritis. We describe a patient who was diagnosed with complicated epidural and paraspinal abscesses after insufficient evaluation and treatment of acute pyelonephritis due to S...
September 2016: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/27637417/concurrent-emphysematous-pyelonephritis-cystitis-and-iliopsoas-abscess-from-discitis-in-a-diabetic-woman
#7
Sung-Yuan Hu, Bor-Jen Lee, Che-An Tsai, Ming-Shun Hsieh
No abstract text is available yet for this article.
September 13, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27624108/-emphysematous-pyelonephritis-with-cardio-pulmonary-arrest-a-case-report
#8
Gaku Yamamichi, Koichi Tsutahara, Sohei Kuribayashi, Masataka Kawamura, Kosuke Nakano, Nozomu Kishimoto, Go Tanigawa, Asako Matsushima, Satoshi Fujimi, Tetsuya Takao, Seiji Yamaguchi
A 40-year-old woman withuntreated type II diabetes mellitus was discovered withcardiopulmonary arrest in her room. On admission, she had ventricular fibrillation. After cardiopulmonary resuscitation, her own pulse restarted. The plasma glucose was 722 mg/dl and venous PH was 6.704. Abdominal computed tomography revealed gas within the parenchyma of the left kidney. We diagnosed her with emphysematous pyelonephritis and conducted emergency nephrectomy. Urinary and blood cultures were positive for Escherichia coli...
August 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27590778/-candiduria-what-now-therapy-of-urinary-tract-infections-with-candida
#9
H Hof
BACKGROUND: Yeasts are found in urine specimens relatively often, especially in the elderly and patients under treatment with broad spectrum antibiotics, i. e. especially in intensive care unit (ICU) patients. In some cases, the number of pathogens is very high, i. e. >10(5)/ml. The clinical relevance of detecting Candida in urine is difficult to assess. In the German S3 guidelines it is apodictically stated that an ascending infection of the urinary tract by yeasts does not occur but this may undoubtedly happen in certain instances in patients at risk, for example in the elderly, in diabetic persons and in the case of foreign bodies in the urinary tract...
September 2, 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27561019/-prognostic-factors-of-morbimortality-in-patients-with-emphysematous-pyelonephritis
#10
León Octavio Torres-Mercado, Miguel Ángel García-Padilla, Eduardo Serrano-Brambila, Efraín Maldonado-Alcaraz, Virgilio Augusto López-Sámano, Guillermo Montoya-Martínez, Jorge Moreno-Palacios
BACKGROUND: Emphysematous pyelonephritis (EPN) is a severe infection of the urinary tract, caused by gas accumulation within the collecting system, the renal parenchyma, and/or the perirenal tissue. The cause of this infection is not known at all; however, it has been suggested that it is produced by the glucose fermentation provoked by enterobacteriaceae or anaerobic organisms. Our objective was to evaluate the predictors of morbidity and mortality in patients diagnosed with EPN. METHODS: It was carried out a historical cohort study of patients diagnosed with EPN in our hospital from March 2005 to December 2014...
2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27458566/skin-disorders-in-peritoneal-dialysis-patients-an-underdiagnosed-subject
#11
Meltem Gursu, Sami Uzun, Derya Topcuoğlu, Leyli Kadriye Koc, Lamiye Yucel, Abdullah Sumnu, Egemen Cebeci, Oktay Ozkan, Ahmet Behlul, Leyla Koc, Savas Ozturk, Rumeyza Kazancioglu
AIM: To examine all skin changes in peritoneal dialysis (PD) patients followed up in our unit. METHODS: Patients on PD program for at least three months without any known chronic skin disease were included in the study. Patients with already diagnosed skin disease, those who have systemic diseases that may cause skin lesions, patients with malignancies and those who did not give informed consent were excluded from the study. All patients were examined by the same predetermined dermatologist with all findings recorded...
July 6, 2016: World Journal of Nephrology
https://www.readbyqxmd.com/read/27393153/pre-and-postoperative-predictors-of-infection-related-complications-in-patients-undergoing-percutaneous-nephrolithotomy
#12
Marcelino Rivera, Boyd Viers, Patrick Cockerill, Deepak Agarwal, Ramila Mehta, Amy Krambeck
INTRODUCTION: We aim to describe pre- and postoperative predictors of infection-related complications in individuals undergoing percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS: Patients treated with PCNL from 2009 to 2013 were reviewed. Patients with positive urine or stone cultures received extended antimicrobial treatment. All others received 7 days of empirical therapy preoperatively and postoperatively. Pre- and postoperative predictors of infectious complication were identified...
September 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27366713/emphysematous-pyelonephritis-a-10-year-experience-with-26-cases
#13
Raiz Ahmad Misgar, Idrees Mubarik, Arshad Iqbal Wani, Mir Iftikhar Bashir, Mahroosa Ramzan, Bashir Ahmad Laway
BACKGROUND: Emphysematous pyelonephritis (EPN) is a necrotizing infection which results in gas within the renal parenchyma, collecting system, or perinephric tissue. A majority of cases occur in patients with diabetes mellitus (DM). In EPN, early aggressive medical treatment may avoid nephrectomy. AIMS: The aim of this study was to analyze the characteristics of patients with EPN with respect to patient demographics, clinical presentation, diagnostic investigations, microbiological findings, treatment modality and outcome, and the influence of prognostic factors on the outcome...
July 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27330732/retrograde-pyelonephritis-and-lumbar-spondylitis-as-a-result-of-salmonella-typhi-in-a-type%C3%A2-2-diabetes-patient-with-neurogenic-bladder
#14
Tatsuya Fukuda, Ryotaro Bouchi, Isao Minami, Norihiko Ohara, Yujiro Nakano, Rie Nishitani, Masanori Murakami, Takato Takeuchi, Momoko Akihisa, Masamichi Fujita, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto, Yoshihiro Ogawa
We present a case of a 62-year-old diabetic woman with acute pyelonephritis and spondylitis caused by Salmonella typhi. She was admitted to Tokyo Medical Dental University Hospital, Tokyo, Japan, because of unconsciousness and was diagnosed with sepsis by retrograde pyelonephritis as a result of Salmonella typhi. Antibiotics treatment was immediately started; however, she subsequently developed lumbar spondylitis, and long-term conservative treatment with antibiotics and a fixing device were required. This is the first report of a diabetic patient who developed retrograde urinary tract infection with Salmonella typhi, followed by sepsis and spondylitis...
May 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27237301/clinical-value-of-pathologic-examination-of-non-neoplastic-kidney-in-patients-with-upper-urinary-tract-malignancies
#15
Jee Wan Wee, Hye Ran Kang, Soon Hyo Kwon, Jin Seok Jeon, Dong Cheol Han, So-Young Jin, Won Jae Yang, Hyunjin Noh
BACKGROUND/AIMS: While surgical resection remains the standard of care in the treatment of upper urinary tract malignancies, nephrectomy is a risk factor for the development of chronic kidney disease (CKD). The aim of this study was to determine whether histologic evaluation of non-neoplastic kidney could enable early identification of unrecognized kidney disease and could be of prognostic value in predicting postoperative renal outcomes. METHODS: We retrospectively analyzed 51 patients with upper urinary tract malignancies who received uninephrectomy or uninephroureterectomy...
July 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27135957/the-role-of-nicotinamide-phosphoribosyltransferase-in-pregnancy-a-review
#16
Blake Porter, Shilpa Babbar, Shui Qing Ye, Dev Maulik
Nicotinamide phosphoribosyltransferase (NAMPT) was first reported in 1994 and has been explored in various human disease processes. However, until recently, very little has been done to define the role of NAMPT in pregnancy. NAMPT is a 52 kDa protein that has diverse functions in the human body, acting as a growth factor, cytokine, an enzyme, and an insulinomimetic agent. Initial studies examined NAMPT expression in fetal membranes and its effects on the amnion. Later research in nonpregnant studies showed an insulinomimetic effect, and attention focused on its role in gestational diabetes...
December 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27133886/-a-case-of-primary-renal-malignant-lymphoma-initially-managed-as-severe-pyelonephritis-in-a-patient-undergoing-hemodialysis
#17
Yuji Fujizuka, Tomomi Suzuki, Koichi Suzuki, Yutaka Kubota, Yasushige Matsuo
A 75-year-old male undergoing hemodialysis because of diabetic nephropathy was referred to our hospital complaining of high fever and swelling of the left kidney. Our initial clinical diagnosis was severe pyelonephritis. He was initially treated with intravenous antibiotics and his clinical symptoms subsequently improved but only temporarily. The high fever soon recurred, accompanied by progressive thrombocytopenia. His general condition deteriorated despite conservative treatment. He then underwent nephrectomy of the left kidney...
March 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27104571/the-paradigm-shift-to-non-treatment-of-asymptomatic-bacteriuria
#18
Lindsay E Nicolle
Asymptomatic bacteriuria, also called asymptomatic urinary infection, is a common finding in healthy women, and in women and men with abnormalities of the genitourinary tract. The characterization and introduction of the quantitative urine culture in the 1950s first allowed the reliable recognition of asymptomatic bacteriuria. The observations that a substantial proportion of patients with chronic pyelonephritis at autopsy had no history of symptomatic urinary infection, and the high frequency of pyelonephritis observed in pregnant women with untreated asymptomatic bacteriuria, supported a conclusion that asymptomatic bacteriuria was harmful...
2016: Pathogens
https://www.readbyqxmd.com/read/27060943/influence-of-incipient-dementia-on-hospitalization-for-primary-care-sensitive-conditions-a-population-based-cohort-study
#19
Clément Pimouguet, Debora Rizzuto, Johan Fastbom, Mårten Lagergren, Laura Fratiglioni, Weili Xu
BACKGROUND: Studies have reported that moderate/severe stages of dementia are linked to increased hospitalization rates, but little is known about the influence of incipient dementia on hospitalizations for primary care sensitive conditions (PCSCs). OBJECTIVE: To examine the associations between incipient dementia and hospitalization outcomes, including all-cause and PCSC hospitalization. METHODS: A total of 2,268 dementia-free participants in the Swedish National study on Aging and Care-Kungsholmen were interviewed and clinically examined at baseline...
March 8, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/26916045/-urosepsis-in-geriatric-patients
#20
H J Heppner, F Yapan, A Wiedemann
Due to the demographic shift, increasing numbers of geriatric patients are admitted to acute care hospitals of all levels of care. This means that special challenges must be met in the medical care and management of these patients.Immunosenescence and multimorbidity make elderly patients vulnerable to infectious diseases. Urinary tract infections range from "simple" cystitis to pyelonephritis and urosepsis and, at 25%, are the second most common form of infection in geriatric patients. It is often difficult to make a diagnosis because typical symptoms do not always occur...
February 2016: Aktuelle Urologie
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